Michael Platten - Publications

Affiliations: 
Hertie-Institute for Clinical Brain Research Eberhard Karls Universität Tübingen, Tübingen, Baden-Württemberg, Germany 

111 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Hunger J, Schregel K, Boztepe B, Agardy DA, Turco V, Karimian-Jazi K, Weidenfeld I, Streibel Y, Fischer M, Sturm V, Santarella-Mellwig R, Kilian M, Jähne K, Sahm K, Wick W, ... ... Platten M, et al. nanoparticle-based T cell imaging can predict therapy response towards adoptive T cell therapy in experimental glioma. Theranostics. 13: 5170-5182. PMID 37908732 DOI: 10.7150/thno.87248  0.671
2023 Grassl N, Poschke I, Lindner K, Bunse L, Mildenberger I, Boschert T, Jähne K, Green EW, Hülsmeyer I, Jünger S, Kessler T, Suwala AK, Eisele P, Breckwoldt MO, Vajkoczy P, ... ... Platten M, et al. A H3K27M-targeted vaccine in adults with diffuse midline glioma. Nature Medicine. 29: 2586-2592. PMID 37735561 DOI: 10.1038/s41591-023-02555-6  0.675
2023 Schregel K, Heinz L, Hunger J, Pan C, Bode J, Fischer M, Sturm V, Venkataramani V, Karimian-Jazi K, Agardy DA, Streibel Y, Zerelles R, Wick W, Heiland S, Bunse T, ... ... Platten M, et al. A cellular ground truth to develop MRI signatures in glioma models by correlative light sheet microscopy and atlas-based co-registration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 37429718 DOI: 10.1523/JNEUROSCI.1470-22.2023  0.696
2023 Turco V, Pfleiderer K, Hunger J, Horvat NK, Karimian-Jazi K, Schregel K, Fischer M, Brugnara G, Jähne K, Sturm V, Streibel Y, Nguyen D, Altamura S, Agardy DA, Soni SS, ... ... Platten M, et al. T cell-independent eradication of experimental glioma by intravenous TLR7/8-agonist-loaded nanoparticles. Nature Communications. 14: 771. PMID 36774352 DOI: 10.1038/s41467-023-36321-6  0.723
2022 Miller JJ, Gonzalez Castro LN, McBrayer S, Weller M, Cloughesy T, Portnow J, Andronesi O, Barnholtz-Sloan JS, Baumert BG, Berger MS, Bi WL, Bindra R, Cahill DP, Chang SM, Costello JF, ... ... Platten M, et al. Isocitrate dehydrogenase (IDH) mutant gliomas: A Society for Neuro-Oncology (SNO) consensus review on diagnosis, management, and future directions. Neuro-Oncology. PMID 36239925 DOI: 10.1093/neuonc/noac207  0.447
2022 Reinhardt A, Pfister K, Schrimpf D, Stichel D, Sahm F, Reuss DE, Capper D, Wefers AK, Ebrahimi A, Sill M, Felsberg J, Reifenberger G, Becker A, Prinz M, Staszewski O, ... ... Platten M, et al. Anaplastic ganglioglioma - a diagnosis comprising several distinct tumour types. Neuropathology and Applied Neurobiology. e12847. PMID 35977725 DOI: 10.1111/nan.12847  0.397
2021 Kilian M, Friedrich M, Sanghvi K, Green E, Pusch S, Kawauchi D, Löwer M, Sonner JK, Krämer C, Zaman J, Jung S, Breckwoldt MO, Willimksy G, Eichmüller SB, von Deimling A, ... ... Platten M, et al. T cell receptor therapy targeting mutant capicua transcriptional repressor in experimental gliomas. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 34782365 DOI: 10.1158/1078-0432.CCR-21-1881  0.681
2021 Blobner J, Kilian M, Tan CL, Aslan K, Sanghvi K, Meyer J, Fischer M, Jähne K, Breckwoldt MO, Sahm F, von Deimling A, Bendszus M, Wick W, Platten M, Green E, et al. Comparative evaluation of T-cell receptors in experimental glioma-draining lymph nodes. Neuro-Oncology Advances. 3: vdab147. PMID 34738084 DOI: 10.1093/noajnl/vdab147  0.681
2021 Platten M, Bunse L, Wick A, Bunse T, Le Cornet L, Harting I, Sahm F, Sanghvi K, Tan CL, Poschke I, Green E, Justesen S, Behrens GA, Breckwoldt MO, Freitag A, et al. A vaccine targeting mutant IDH1 in newly diagnosed glioma. Nature. PMID 33762734 DOI: 10.1038/s41586-021-03363-z  0.675
2021 Koelsche C, Schrimpf D, Stichel D, Sill M, Sahm F, Reuss DE, Blattner M, Worst B, Heilig CE, Beck K, Horak P, Kreutzfeldt S, Paff E, Stark S, Johann P, ... ... Platten M, et al. Sarcoma classification by DNA methylation profiling. Nature Communications. 12: 498. PMID 33479225 DOI: 10.1038/s41467-020-20603-4  0.366
2020 Hahn A, Bode J, Alexander A, Karimian-Jazi K, Schregel K, Schwarz D, Sommerkamp AC, Krüwel T, Abdollahi A, Wick W, Platten M, Bendszus M, Tews B, Kurz FT, Breckwoldt MO. Large-scale characterization of the microvascular geometry in development and disease by tissue clearing and quantitative ultramicroscopy. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X20961854. PMID 33043767 DOI: 10.1177/0271678X20961854  0.658
2020 Kickingereder P, Brugnara G, Hansen MB, Nowosielski M, Pflüger I, Schell M, Isensee F, Foltyn M, Neuberger U, Kessler T, Sahm F, Wick A, Heiland S, Weller M, Platten M, et al. Noninvasive Characterization of Tumor Angiogenesis and Oxygenation in Bevacizumab-treated Recurrent Glioblastoma by Using Dynamic Susceptibility MRI: Secondary Analysis of the European Organization for Research and Treatment of Cancer 26101 Trial. Radiology. 200978. PMID 32720870 DOI: 10.1148/Radiol.2020200978  0.374
2020 Grassl N, Bunse L, Beutel T, Klockziem M, Gass A, Platten M, Eisele P. Nivolumab for Treatment of Progressive Multifocal Leukoencephalopathy in Sézary Syndrome. European Journal of Neurology. PMID 32644207 DOI: 10.1111/Ene.14433  0.334
2020 Kudo T, Prentzell MT, Mohapatra SR, Sahm F, Zhao Z, Grummt I, Wick W, Opitz CA, Platten M, Green EW. Constitutive Expression of the Immunosuppressive Tryptophan Dioxygenase TDO2 in Glioblastoma Is Driven by the Transcription Factor C/EBPβ. Frontiers in Immunology. 11: 657. PMID 32477324 DOI: 10.3389/Fimmu.2020.00657  0.345
2020 Schell M, Pflüger I, Brugnara G, Isensee F, Neuberger U, Foltyn M, Kessler T, Sahm F, Wick A, Nowosielski M, Heiland S, Weller M, Platten M, Maier-Hein KH, von Deimling A, et al. Validation of diffusion MRI phenotypes for predicting response to bevacizumab in recurrent glioblastoma: post-hoc analysis of the EORTC-26101 trial. Neuro-Oncology. PMID 32393964 DOI: 10.1093/Neuonc/Noaa120  0.304
2020 Wen PY, Weller M, Lee EQ, Alexander BA, Barnholtz-Sloan JS, Barthel FP, Batchelor TT, Bindra RS, Chang SM, Chiocca EA, Cloughesy TF, DeGroot JF, Galanis E, Gilbert MR, Hegi ME, ... ... Platten M, et al. Glioblastoma in Adults: A Society for Neuro-Oncology (SNO) and European Society of Neuro-Oncology (EANO) Consensus Review on Current Management and Future Directions. Neuro-Oncology. PMID 32328653 DOI: 10.1093/Neuonc/Noaa106  0.337
2020 Aslan K, Turco V, Blobner J, Sonner JK, Liuzzi AR, Núñez NG, De Feo D, Kickingereder P, Fischer M, Green E, Sadik A, Friedrich M, Sanghvi K, Kilian M, Cichon F, ... ... Platten M, et al. Heterogeneity of response to immune checkpoint blockade in hypermutated experimental gliomas. Nature Communications. 11: 931. PMID 32071302 DOI: 10.1038/S41467-020-14642-0  0.705
2020 Karimian-Jazi K, Münch P, Alexander A, Fischer M, Pfleiderer K, Piechutta M, Karreman MA, Solecki GM, Berghoff AS, Friedrich M, Deumelandt K, Kurz FT, Wick W, Heiland S, Bendszus M, ... ... Platten M, et al. Monitoring innate immune cell dynamics in the glioma microenvironment by magnetic resonance imaging and multiphoton microscopy (MR-MPM). Theranostics. 10: 1873-1883. PMID 32042342 DOI: 10.7150/thno.38659  0.69
2019 Opitz CA, Somarribas Patterson LF, Mohapatra SR, Dewi DL, Sadik A, Platten M, Trump S. The therapeutic potential of targeting tryptophan catabolism in cancer. British Journal of Cancer. PMID 31819194 DOI: 10.1038/S41416-019-0664-6  0.305
2019 Reinhardt A, Stichel D, Schrimpf D, Koelsche C, Wefers AK, Ebrahimi A, Sievers P, Huang K, Casalini MB, Fernández-Klett F, Suwala A, Weller M, Gramatzki D, Felsberg J, Reifenberger G, ... ... Platten M, et al. Tumors diagnosed as cerebellar glioblastoma comprise distinct molecular entities. Acta Neuropathologica Communications. 7: 163. PMID 31661039 DOI: 10.1186/S40478-019-0801-8  0.655
2019 Shraibman B, Barnea E, Kadosh DM, Haimovich Y, Slobodin G, Rosner I, López-Larrea C, Hilf N, Kuttruff S, Song C, Britten C, Castle J, Kreiter S, Frenzel K, Tatagiba M, ... ... Platten M, et al. Withdrawal: Identification of tumor antigens among the HLA peptidomes of glioblastoma tumors and plasma. Molecular & Cellular Proteomics : McP. 18: 1270. PMID 31154440 DOI: 10.1074/Mcp.W119.001571  0.351
2019 Nowosielski M, Gorlia T, Bromberg JEC, Sahm F, Harting I, Kickingereder P, Brandes AA, Taphoorn MJB, Taal W, Domont J, Idbaih A, Campone M, Clement PM, Weller M, Fabbro M, ... ... Platten M, et al. Imaging necrosis during treatment is associated with worse survival in EORTC 26101 study. Neurology. PMID 31076534 DOI: 10.1212/Wnl.0000000000007643  0.309
2019 Schwarz D, Niederle T, Münch P, Hielscher T, Hassel JC, Schlemmer HP, Platten M, Winkler F, Wick W, Heiland S, Delorme S, Bendszus M, Bäumer P, Breckwoldt MO. Susceptibility-weighted imaging in malignant melanoma brain metastasis. Journal of Magnetic Resonance Imaging : Jmri. PMID 30793419 DOI: 10.1002/Jmri.26692  0.67
2019 Eisele P, Konstandin S, Szabo K, Ebert A, Roßmanith C, Paschke N, Kerschensteiner M, Platten M, Schoenberg SO, Schad LR, Gass A. Temporal evolution of acute multiple sclerosis lesions on serial sodium (Na) MRI. Multiple Sclerosis and Related Disorders. 29: 48-54. PMID 30669020 DOI: 10.1016/J.Msard.2019.01.027  0.607
2019 Wick W, Wick A, Platten M, Chinot OL, Van Den Bent MJ, Dhermain F, Mansour M, Podola L, Lubenau H. Oral DNA vaccination targeting VEGFR-2 combined with anti-PD-L1 avelumab in patients with progressive glioblastoma, a phase I/II study: NCT03750071. Journal of Clinical Oncology. 37: TPS2076-TPS2076. DOI: 10.1200/Jco.2019.37.15_Suppl.Tps2076  0.352
2019 Wick W, Kessler T, Platten M, Meisner C, Bamberg M, Herrlinger U, Happold C, Weisang S, Boelting H, Steinbach J, Reifenberger G, Sahm F, von Deimling A, Wick A, Weller M. Impact of predictive impact of MGMT promoter methylation in malignant astrocytomas depends on the methylation subgroup. Journal of Clinical Oncology. 37: 2013-2013. DOI: 10.1200/Jco.2019.37.15_Suppl.2013  0.327
2019 Friedrich M, Bunse L, Bunse T, Green E, Kessler T, Pusch S, Deumelandt K, Carretero R, Deimling Av, Quintana FJ, Wick W, Platten M. Abstract PR15: The oncometabolite R-2-Hydroxyglutarate suppresses the innate immune microenvironment of IDH1-mutated gliomas via aryl hydrocarbon receptor signaling Cancer Immunology Research. 7. DOI: 10.1158/2326-6074.Cricimteatiaacr18-Pr15  0.369
2019 Deumelandt K, Blobner J, Sonner JK, Friedrich M, Green E, Breckwoldt MO, Fischer M, Meyer J, Sahm F, Schrimpf D, Deimling Av, Platten M. Abstract B075: Modeling response and resistance to immune checkpoint blockade in syngeneic mouse glioma Cancer Immunology Research. 7. DOI: 10.1158/2326-6074.Cricimteatiaacr18-B075  0.387
2019 Ulges A, Hilf N, Wick W, Platten M, Dietrich P, Frenzel K, Admon A, Burg SSHvd, Deimling Av, Straten Pt, Gouttefangeas C, Kroep JR, Martínez-Ricarte F, Okada H, Ottensmeier CH, et al. Abstract A020: Immunomonitoring for actively personalized peptide vaccines (APVACs) during immunotherapeutic treatment of glioblastoma Cancer Immunology Research. 7. DOI: 10.1158/2326-6074.Cricimteatiaacr18-A020  0.348
2019 Schmees N, Gutcher I, Roehn U, Irlbacher H, Stoeckigt D, Bader B, Kober C, Roese L, Carretero R, Oezen I, Zorn L, Platten M, Hartung IV, Kreft B, Weinmann H. Abstract 4454: Identification of BAY-218, a potent and selective small-molecule AhR inhibitor, as a new modality to counteract tumor immunosuppression Cancer Research. 79: 4454-4454. DOI: 10.1158/1538-7445.Am2019-4454  0.368
2018 Breckwoldt MO, Bode J, Sahm F, Krüwel T, Solecki G, Hahn A, Wirthschaft P, Berghoff AS, Haas M, Venkataramani V, von Deimling A, Wick W, Herold-Mende C, Heiland S, Platten M, et al. Correlated MRI and Ultramicroscopy (MR-UM) of Brain Tumors Reveals Vast Heterogeneity of Tumor Infiltration and Neoangiogenesis in Preclinical Models and Human Disease. Frontiers in Neuroscience. 12: 1004. PMID 30686972 DOI: 10.3389/Fnins.2018.01004  0.71
2018 Hoffmann A, Pfeil J, Mueller AK, Jin J, Deumelandt K, Helluy X, Wang C, Heiland S, Platten M, Chen JW, Bendszus M, Breckwoldt MO. MRI of Iron Oxide Nanoparticles and Myeloperoxidase Activity Links Inflammation to Brain Edema in Experimental Cerebral Malaria. Radiology. 181051. PMID 30615566 DOI: 10.1148/Radiol.2018181051  0.669
2018 Adam I, Dewi DL, Mooiweer J, Sadik A, Mohapatra SR, Berdel B, Keil M, Sonner JK, Thedieck K, Rose AJ, Platten M, Heiland I, Trump S, Opitz CA. Upregulation of tryptophanyl-tRNA synthethase adapts human cancer cells to nutritional stress caused by tryptophan degradation. Oncoimmunology. 7: e1486353. PMID 30524887 DOI: 10.1080/2162402X.2018.1486353  0.333
2018 Wick W, Dettmer S, Berberich A, Kessler T, Karapanagiotou-Schenkel I, Wick A, Winkler F, Pfaff E, Brors B, Debus J, Unterberg A, Bendszus M, Herold-Mende C, Eisenmenger A, von Deimling A, ... ... Platten M, et al. N2M2 (NOA20) phase I/II trial of molecularly matched targeted therapies plus radiotherapy in patients with newly diagnosed non-MGMT hypermethylated glioblastoma. Neuro-Oncology. PMID 30277538 DOI: 10.1093/Neuonc/Noy161  0.315
2018 Berberich A, Kessler T, Thomé CM, Pusch S, Hielscher T, Sahm F, Oezen I, Schmitt LM, Ciprut S, Hucke N, Rübmann P, Fischer M, Lemke D, Breckwoldt MO, von Deimling A, ... ... Platten M, et al. Targeting resistance against the MDM2 inhibitor RG7388 in glioblastoma cells by the MEK inhibitor trametinib. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 30274984 DOI: 10.1158/1078-0432.Ccr-18-1580  0.66
2018 Platten M. T cells engineered to home in on brain cancer. Nature. 561: 319-320. PMID 30224728 DOI: 10.1038/D41586-018-05883-7  0.311
2018 Friedrich M, Bunse L, Wick W, Platten M. Perspectives of immunotherapy in isocitrate dehydrogenase-mutant gliomas. Current Opinion in Oncology. PMID 30102604 DOI: 10.1097/Cco.0000000000000478  0.316
2018 Shraibman B, Barnea E, Melamed Kadosh D, Haimovich Y, Slobodin G, Rosner I, López-Larrea C, Hilf N, Kuttruff S, Song C, Britten C, Castle J, Kreiter S, Frenzel K, Tatagiba M, ... ... Platten M, et al. Identification of tumor antigens among the HLA peptidomes of Glioblastoma tumors and plasma. Molecular & Cellular Proteomics : McP. PMID 30072578 DOI: 10.1074/Mcp.Ra118.000792  0.355
2018 Berberich A, Hielscher T, Kickingereder P, Winkler F, Drüschler K, Riedemann L, Arzt M, Kessler T, Platten M, von Deimling A, Wick W, Sahm F, Bendszus M, Wick A. Non-measurable speckled contrast-enhancing lesions appearing during course of disease are associated with IDH mutation in high-grade astrocytoma patients. International Journal of Radiation Oncology, Biology, Physics. PMID 30071292 DOI: 10.1016/J.Ijrobp.2018.07.2004  0.343
2018 Bunse L, Pusch S, Bunse T, Sahm F, Sanghvi K, Friedrich M, Alansary D, Sonner JK, Green E, Deumelandt K, Kilian M, Neftel C, Uhlig S, Kessler T, von Landenberg A, ... ... Platten M, et al. Suppression of antitumor T cell immunity by the oncometabolite (R)-2-hydroxyglutarate. Nature Medicine. PMID 29988124 DOI: 10.1038/S41591-018-0095-6  0.736
2018 Capper D, Stichel D, Sahm F, Jones DTW, Schrimpf D, Sill M, Schmid S, Hovestadt V, Reuss DE, Koelsche C, Reinhardt A, Wefers AK, Huang K, Sievers P, Ebrahimi A, ... ... Platten M, et al. Practical implementation of DNA methylation and copy-number-based CNS tumor diagnostics: the Heidelberg experience. Acta Neuropathologica. PMID 29967940 DOI: 10.1007/S00401-018-1879-Y  0.339
2018 Shirahata M, Ono T, Stichel D, Schrimpf D, Reuss DE, Sahm F, Koelsche C, Wefers A, Reinhardt A, Huang K, Sievers P, Shimizu H, Nanjo H, Kobayashi Y, Miyake Y, ... ... Platten M, et al. Novel, improved grading system(s) for IDH-mutant astrocytic gliomas. Acta Neuropathologica. PMID 29687258 DOI: 10.1007/S00401-018-1849-4  0.563
2018 Yamauchi Y, Safi S, Blattner C, Rathinasamy A, Umansky L, Juenger S, Warth A, Eichhorn M, Muley T, Herth FJF, Dienemann H, Platten M, Beckhove P, Utikal J, Hoffmann H, et al. Circulating and Tumor Myeloid-derived Suppressor Cells in Resectable Non-small-cell Lung Cancer. American Journal of Respiratory and Critical Care Medicine. PMID 29617574 DOI: 10.1164/Rccm.201708-1707Oc  0.365
2018 Reinhardt A, Stichel D, Schrimpf D, Sahm F, Korshunov A, Reuss DE, Koelsche C, Huang K, Wefers AK, Hovestadt V, Sill M, Gramatzki D, Felsberg J, Reifenberger G, Koch A, ... ... Platten M, et al. Anaplastic astrocytoma with piloid features, a novel molecular class of IDH wildtype glioma with recurrent MAPK pathway, CDKN2A/B and ATRX alterations. Acta Neuropathologica. PMID 29564591 DOI: 10.1007/S00401-018-1837-8  0.707
2018 Platten M, Reardon DA. Concepts for Immunotherapies in Gliomas. Seminars in Neurology. 38: 62-72. PMID 29548053 DOI: 10.1055/S-0037-1620274  0.393
2018 Capper D, Jones DTW, Sill M, Hovestadt V, Schrimpf D, Sturm D, Koelsche C, Sahm F, Chavez L, Reuss DE, Kratz A, Wefers AK, Huang K, Pajtler KW, Schweizer L, ... ... Platten M, et al. DNA methylation-based classification of central nervous system tumours. Nature. PMID 29539639 DOI: 10.1038/Nature26000  0.653
2018 Schwarzbach CJ, Ebert A, Hennerici MG, Neumaier-Probst E, Platten M, Fatar M. Off-label use of IV t-PA in patients with intracranial neoplasm and cavernoma. Therapeutic Advances in Neurological Disorders. 11: 1756285617753423. PMID 29449886 DOI: 10.1177/1756285617753423  0.314
2018 Rabe JH, A Sammour D, Schulz S, Munteanu B, Ott M, Ochs K, Hohenberger P, Marx A, Platten M, Opitz CA, Ory DS, Hopf C. Fourier Transform Infrared Microscopy Enables Guidance of Automated Mass Spectrometry Imaging to Predefined Tissue Morphologies. Scientific Reports. 8: 313. PMID 29321555 DOI: 10.1038/S41598-017-18477-6  0.319
2018 Wick W, Wick A, Sahm F, Riehl D, von Deimling A, Bendszus M, Kickingereder P, Beckhove P, Schmitz-Winnenthal FH, Jungk C, Wieckowski S, Podola L, Herold-Mende C, Unterberg A, Platten M. VXM01 phase I study in patients with progressive glioblastoma: Final results. Journal of Clinical Oncology. 36: 2017-2017. DOI: 10.1200/Jco.2018.36.15_Suppl.2017  0.344
2018 Lu K, Bunse L, Sahm F, Sanghvi K, Ratliff M, Hänggi D, von Deimling A, Sahin U, Wick W, Green E, Platten M. P04.52 Spontaneous intratumoral T cell responses against glioblastoma-associated antigens Neuro-Oncology. 20: iii291-iii291. DOI: 10.1093/Neuonc/Noy139.286  0.305
2018 Zhang X, Sahm K, Sonner J, Jähne K, Breckwoldt M, Piechutta M, Häring P, Winkler F, Wick W, Platten M. P04.34 Low-dose irradiation increases recruitment and effector function of tumor-specific T cells in experimental gliomas Neuro-Oncology. 20: iii286-iii286. DOI: 10.1093/Neuonc/Noy139.268  0.363
2017 Costa da Silva M, Breckwoldt MO, Vinchi F, Correia MP, Stojanovic A, Thielmann CM, Meister M, Muley T, Warth A, Platten M, Hentze MW, Cerwenka A, Muckenthaler MU. Iron Induces Anti-tumor Activity in Tumor-Associated Macrophages. Frontiers in Immunology. 8: 1479. PMID 29167669 DOI: 10.3389/Fimmu.2017.01479  0.672
2017 Pfaff E, Kessler T, Balasubramanian GP, Berberich A, Schrimpf D, Wick A, Debus J, Unterberg A, Bendszus M, Herold-Mende C, Capper D, Schenkel I, Eisenmenger A, Dettmer S, Brors B, ... Platten M, et al. Feasibility of real-time molecular profiling for patients with newly diagnosed glioblastoma without MGMT promoter-hypermethylation - the NCT Neuro Master Match (N2M2) pilot study. Neuro-Oncology. PMID 29165638 DOI: 10.1093/Neuonc/Nox216  0.352
2017 Wick A, Kessler T, Elia AEH, Winkler F, Batchelor TT, Platten M, Wick W. Glioblastoma in the elderly: solid conclusions built on shifting sand? Neuro-Oncology. PMID 29016815 DOI: 10.1093/Neuonc/Nox133  0.301
2017 Kessler T, Sahm F, Sadik A, Stichel D, Hertenstein A, Reifenberger G, Zacher A, Sabel M, Tabatabai G, Steinbach J, Sure U, Krex D, Grosu AL, Bewerunge-Hudler M, Jones D, ... ... Platten M, et al. Molecular differences in IDH wildtype glioblastoma according to MGMT promoter methylation. Neuro-Oncology. PMID 29016808 DOI: 10.1093/Neuonc/Nox160  0.318
2017 Ochs K, Ott M, Bunse T, Sahm F, Bunse L, Deumelandt K, Sonner JK, Keil M, von Deimling A, Wick W, Platten M. K27M-mutant histone-3 as a novel target for glioma immunotherapy. Oncoimmunology. 6: e1328340. PMID 28811969 DOI: 10.1080/2162402X.2017.1328340  0.348
2017 Eisele P, Szabo K, Alonso A, Ong M, Platten M, Schoenberg SO, Gass A. Lack of T1 hyperintensity in the dentate nucleus after 15 administrations of a macrocyclic contrast agent in multiple sclerosis. Journal of Neurology, Neurosurgery, and Psychiatry. PMID 28710325 DOI: 10.1136/Jnnp-2017-316102  0.313
2017 Jung E, Osswald M, Blaes J, Wiestler B, Sahm F, Schmenger T, Solecki G, Deumelandt K, Kurz FT, Xie R, Weil S, Heil O, Thomé C, Gömmel M, Syed M, ... ... Platten M, et al. Tweety-homologue 1 drives brain colonization of gliomas. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28607172 DOI: 10.1523/Jneurosci.3532-16.2017  0.412
2017 Weller M, Roth P, Preusser M, Wick W, Reardon DA, Platten M, Sampson JH. Vaccine-based immunotherapeutic approaches to gliomas and beyond. Nature Reviews. Neurology. PMID 28497804 DOI: 10.1038/Nrneurol.2017.64  0.33
2017 Lanz TV, Williams SK, Stojic A, Iwantscheff S, Sonner JK, Grabitz C, Becker S, Böhler LI, Mohapatra SR, Sahm F, Küblbeck G, Nakamura T, Funakoshi H, Opitz CA, Wick W, ... ... Platten M, et al. Tryptophan-2,3-Dioxygenase (TDO) deficiency is associated with subclinical neuroprotection in a mouse model of multiple sclerosis. Scientific Reports. 7: 41271. PMID 28117398 DOI: 10.1038/Srep41271  0.32
2017 Wick W, Wick A, Nowosielski M, Sahm F, Riehl D, Arzt M, von Deimling A, Bendszus M, Kickingereder P, Bonekamp D, Beckhove P, Schmitz-Winnenthal FH, Jungk C, Wieckowski S, Herold-Mende C, ... ... Platten M, et al. VXM01 phase I study in patients with resectable progression of a glioblastoma. Journal of Clinical Oncology. 35: 2061-2061. DOI: 10.1200/JCO.2017.35.15_SUPPL.2061  0.3
2017 Nowosielski M, Gorlia T, Bromberg J, Sahm F, Harting I, Kickingereder P, Brandes A, Taphoorn MJB, Taal W, Domont J, Idbaih A, Campone M, Clement P, Weller M, Fabbro M, ... ... Platten M, et al. NIMG-75. NECROSIS DURING TREATMENT IS ASSOCIATED WITH WORSE SURVIVAL IN RECURRENT GLIOBLASTOMA PATIENTS – POST HOC IMAGE ANALYSIS OF EORTC 26101 Neuro-Oncology. 19: vi159-vi159. DOI: 10.1093/Neuonc/Nox168.647  0.303
2017 Klein M, Reijneveld JC, Idbaih A, Brandes A, Taal W, Clement PM, Domont J, Campone M, Taphoorn MJB, Stupp R, Fabbro M, Rhun EL, Dubois F, Weller M, Golfinopoulos V, ... Platten M, et al. NCOG-19. NEUROCOGNITIVE OUTCOMES OF EORTC BRAIN TUMOR GROUP STUDY 26101 PHASE III TRIAL COMPARING THE COMBINATION OF LOMUSTINE AND BEVACIZUMAB WITH LOMUSTINE ALONE IN GLIOBLASTOMA PATIENTS WITH FIRST PROGRESSION Neuro-Oncology. 19: vi142-vi142. DOI: 10.1093/Neuonc/Nox168.580  0.361
2017 Sanghvi K, Green E, Bunse L, Balasubramanian GP, Hertenstein A, Bunse T, Jones D, Sahm F, Wick W, Platten M. P06.08 BRAINTuNE: Brain Tumor Neoepitope Evaluation for personalized glioma immunotherapy Neuro-Oncology. 19: iii50-iii51. DOI: 10.1093/Neuonc/Nox036.182  0.411
2016 Breckwoldt MO, Gradl J, Hähnel S, Hielscher T, Wildemann B, Diem R, Platten M, Wick W, Heiland S, Bendszus M. Increasing the sensitivity of MRI for the detection of multiple sclerosis lesions by long axial coverage of the spinal cord: a prospective study in 119 patients. Journal of Neurology. PMID 27909801 DOI: 10.1007/s00415-016-8353-3  0.625
2016 Schliesser MG, Claus R, Hielscher T, Grimm C, Weichenhan D, Blaes J, Wiestler B, Hau P, Schramm J, Sahm F, Weiß EK, Weiler M, Baer C, Schmidt-Graf F, Schackert G, ... ... Platten M, et al. Prognostic relevance of miRNA-155 methylation in anaplastic glioma. Oncotarget. PMID 27880937 DOI: 10.18632/Oncotarget.13452  0.405
2016 Kirschbaum K, Sonner JK, Zeller MW, Deumelandt K, Bode J, Sharma R, Krüwel T, Fischer M, Hoffmann A, Costa da Silva M, Muckenthaler MU, Wick W, Tews B, Chen JW, Heiland S, ... ... Platten M, et al. In vivo nanoparticle imaging of innate immune cells can serve as a marker of disease severity in a model of multiple sclerosis. Proceedings of the National Academy of Sciences of the United States of America. PMID 27799546 DOI: 10.1073/pnas.1609397113  0.647
2016 Wick W, Roth P, Hartmann C, Hau P, Nakamura M, Stockhammer F, Sabel MC, Wick A, Koeppen S, Ketter R, Vajkoczy P, Eyupoglu I, Kalff R, Happold C, Galldiks N, ... ... Platten M, et al. Long-term analysis of the NOA-04 randomized phase III trial of sequential radiochemotherapy of anaplastic glioma with PCV or temozolomide. Neuro-Oncology. PMID 27370396 DOI: 10.1093/Neuonc/Now133  0.381
2016 Breckwoldt MO, Bode J, Kurz FT, Hoffmann A, Ochs K, Ott M, Deumelandt K, Krüwel T, Schwarz D, Fischer M, Helluy X, Milford D, Kirschbaum K, Solecki G, Chiblak S, ... ... Platten M, et al. Correlated magnetic resonance imaging and ultramicroscopy (MR-UM) is a tool kit to assess the dynamics of glioma angiogenesis. Elife. 5. PMID 26830460 DOI: 10.7554/eLife.11712  0.686
2016 Sanghvi K, Green E, Bunse T, Bunse L, Sahm F, Omokoko T, Sahin U, Schmitt M, Wick W, Platten M. OS2.6 Identification of IDH1R132H-specific T cell receptors from a humanized mouse model and from glioma patients treated with an IDH1R132H-specific peptide vaccine Neuro-Oncology. 18: iv5-iv6. DOI: 10.1093/Neuonc/Now188.016  0.374
2016 Bunse L, Bunse T, Pusch S, Sahm F, Sanghvi K, Berghoff A, Steadman M, Niemeyer B, Wick W, Platten M. OS2.2 Paracrine impairment of antitumor T cell immunity by IDH1-mutant gliomas Neuro-Oncology. 18: iv4-iv5. DOI: 10.1093/Neuonc/Now188.012  0.337
2016 Thomé C, Blaes J, Sonner J, Deumelandt K, Osswald M, Breckwoldt M, Vajkoczy P, Winkler F, Platten M, Wick W. OS1.3 N-Myc downstream regulated gene 1 (NDRG1) influences the glioma tumor microenvironment Neuro-Oncology. 18: iv2-iv3. DOI: 10.1093/Neuonc/Now188.005  0.339
2015 Ochs K, Ott M, Rauschenbach KJ, Deumelandt K, Sahm F, Opitz CA, von Deimling A, Wick W, Platten M. Tryptophan-2,3-dioxygenase is regulated by prostaglandin E2 in malignant glioma via a positive signaling loop involving prostaglandin E receptor-4. Journal of Neurochemistry. PMID 26708701 DOI: 10.1111/Jnc.13503  0.387
2015 Wick W, Platten M, Wick A, Hertenstein A, Radbruch A, Bendszus M, Winkler F. Current status and future directions of anti-angiogenic therapy for gliomas. Neuro-Oncology. PMID 26459812 DOI: 10.1093/Neuonc/Nov180  0.349
2015 Redaelli C, Gaffarogullari EC, Brune M, Pilz C, Becker S, Sonner J, Jäschke A, Gröne HJ, Wick W, Platten M, Lanz TV. Toxicity of teriflunomide in aryl hydrocarbon receptor deficient mice. Biochemical Pharmacology. 98: 484-92. PMID 26341389 DOI: 10.1016/J.Bcp.2015.08.111  0.315
2015 Reuss DE, Kratz A, Sahm F, Capper D, Schrimpf D, Koelsche C, Hovestadt V, Bewerunge-Hudler M, Jones DT, Schittenhelm J, Mittelbronn M, Rushing E, Simon M, Westphal M, Unterberg A, ... Platten M, et al. Adult IDH wild type astrocytomas biologically and clinically resolve into other tumor entities. Acta Neuropathologica. PMID 26087904 DOI: 10.1007/S00401-015-1454-8  0.392
2015 Reuss DE, Mamatjan Y, Schrimpf D, Capper D, Hovestadt V, Kratz A, Sahm F, Koelsche C, Korshunov A, Olar A, Hartmann C, Reijneveld JC, Wesseling P, Unterberg A, Platten M, et al. IDH mutant diffuse and anaplastic astrocytomas have similar age at presentation and little difference in survival: a grading problem for WHO. Acta Neuropathologica. 129: 867-73. PMID 25962792 DOI: 10.1007/S00401-015-1438-8  0.476
2015 Herrlinger U, Platten M. [Treatment of the glioma microenvironment]. Der Nervenarzt. 86: 684, 686-8, 690-1. PMID 25962344 DOI: 10.1007/S00115-014-4225-1  0.402
2015 Platten M, Wick W. Tregs in gliomas - the jury is still out. Neuro-Oncology. 17: 769-70. PMID 25754090 DOI: 10.1093/Neuonc/Nov034  0.416
2015 Bunse L, Schumacher T, Sahm F, Pusch S, Oezen I, Rauschenbach K, Gonzalez M, Solecki G, Osswald M, Capper D, Wiestler B, Winkler F, Herold-Mende C, von Deimling A, Wick W, ... Platten M, et al. Proximity ligation assay evaluates IDH1R132H presentation in gliomas. The Journal of Clinical Investigation. 125: 593-606. PMID 25555220 DOI: 10.1172/Jci77780  0.352
2014 Wick W, Fricke H, Junge K, Kobyakov G, Martens T, Heese O, Wiestler B, Schliesser MG, von Deimling A, Pichler J, Vetlova E, Harting I, Debus J, Hartmann C, Kunz C, ... Platten M, et al. A phase II, randomized, study of weekly APG101+reirradiation versus reirradiation in progressive glioblastoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 20: 6304-13. PMID 25338498 DOI: 10.1158/1078-0432.CCR-14-0951-T  0.361
2014 Wiestler B, Capper D, Hovestadt V, Sill M, Jones DT, Hartmann C, Felsberg J, Platten M, Feiden W, Keyvani K, Pfister SM, Wiestler OD, Meyermann R, Reifenberger G, Pietsch T, et al. Assessing CpG island methylator phenotype, 1p/19q codeletion, and MGMT promoter methylation from epigenome-wide data in the biomarker cohort of the NOA-04 trial. Neuro-Oncology. 16: 1630-8. PMID 25028501 DOI: 10.1093/Neuonc/Nou138  0.387
2014 Wiestler B, Capper D, Sill M, Jones DT, Hovestadt V, Sturm D, Koelsche C, Bertoni A, Schweizer L, Korshunov A, Weiß EK, Schliesser MG, Radbruch A, Herold-Mende C, Roth P, ... ... Platten M, et al. Integrated DNA methylation and copy-number profiling identify three clinically and biologically relevant groups of anaplastic glioma. Acta Neuropathologica. 128: 561-71. PMID 25008768 DOI: 10.1007/S00401-014-1315-X  0.468
2014 Wick W, Platten M. CMV infection and glioma, a highly controversial concept struggling in the clinical arena. Neuro-Oncology. 16: 332-3. PMID 24523454 DOI: 10.1093/Neuonc/Nou002  0.378
2014 Blaes J, Weiler M, Sahm F, Hentschel B, Osswald M, Czabanka M, Thomé CM, Schliesser MG, Pusch S, Luger S, Winkler F, Radbruch A, Jugold M, Simon M, Steinbach JP, ... ... Platten M, et al. NDRG1 prognosticates the natural course of disease in WHO grade II glioma. Journal of Neuro-Oncology. 117: 25-32. PMID 24395351 DOI: 10.1007/s11060-013-1357-2  0.462
2014 Wick W, Wick A, Platten M. Challenging cytomegalovirus data in glioblastoma. Neuro-Oncology. 16: 165. PMID 24353326 DOI: 10.1093/Neuonc/Not212  0.301
2014 Wiestler B, Capper D, Hovestadt V, Sill M, Jones D, Hartmann C, Felsberg J, Platten M, Keyvani K, Pfister S, Wiestler O, Meyermann R, Reifenberger G, Pietsch T, von Deimling A, et al. Determining the glioma CpG island methylator phenotype, 1p/19q codeletion, and MGMT promoter methylation from epigenome-wide methylation data in the biomarker cohort of the NOA-04 trial. Journal of Clinical Oncology. 32: 2017-2017. DOI: 10.1200/Jco.2014.32.15_Suppl.2017  0.315
2014 Wick W, Gorlia T, Van Den Bent MJ, Vecht CJ, Steuve J, Brandes AA, Platten M, Kosch MA, Hegi ME, Lhermitte B, Golfinopoulos V, Campone M, Frenel J, Taphoorn MJ, Pesce GA, et al. Radiation therapy and concurrent plus adjuvant temsirolimus (CCI-779) versus chemoirradiation with temozolomide in newly diagnosed glioblastoma without methylation of the MGMT gene promoter. Journal of Clinical Oncology. 32: 2003-2003. DOI: 10.1200/Jco.2014.32.15_Suppl.2003  0.326
2014 Wick W, Wiestler B, Capper D, Sill M, Hovestadt V, Schliesser MG, Weiss E, Jones DTW, Roth P, Pfister SM, Korshunov A, Platten M, Reifenberger G, von Deimling A, Weller M. PROGNOSTIC AND PREDICTIVE BIOMARKER-BASED SUBGROUPS IN THE NOA-04 TRIAL Neuro-Oncology. 16: iii4-iii4. DOI: 10.1093/Neuonc/Nou206.14  0.382
2013 Koelsche C, Sahm F, Capper D, Reuss D, Sturm D, Jones DT, Kool M, Northcott PA, Wiestler B, Böhmer K, Meyer J, Mawrin C, Hartmann C, Mittelbronn M, Platten M, et al. Distribution of TERT promoter mutations in pediatric and adult tumors of the nervous system. Acta Neuropathologica. 126: 907-15. PMID 24154961 DOI: 10.1007/S00401-013-1195-5  0.449
2013 Lanz TV, Becker S, Osswald M, Bittner S, Schuhmann MK, Opitz CA, Gaikwad S, Wiestler B, Litzenburger UM, Sahm F, Ott M, Iwantscheff S, Grabitz C, Mittelbronn M, von Deimling A, ... ... Platten M, et al. Protein kinase Cβ as a therapeutic target stabilizing blood-brain barrier disruption in experimental autoimmune encephalomyelitis. Proceedings of the National Academy of Sciences of the United States of America. 110: 14735-40. PMID 23959874 DOI: 10.1073/Pnas.1302569110  0.327
2013 Wick W, Steinbach JP, Platten M, Hartmann C, Wenz F, von Deimling A, Shei P, Moreau-Donnet V, Stoffregen C, Combs SE. Enzastaurin before and concomitant with radiation therapy, followed by enzastaurin maintenance therapy, in patients with newly diagnosed glioblastoma without MGMT promoter hypermethylation. Neuro-Oncology. 15: 1405-12. PMID 23911595 DOI: 10.1093/Neuonc/Not100  0.477
2013 Platten M, Wick W, Opitz C. [Immune modulation by tryptophan metabolism: relevance for autoimmune and tumor diseases]. Deutsche Medizinische Wochenschrift (1946). 138: 1478-82. PMID 23821452 DOI: 10.1055/S-0033-1343222  0.329
2013 Wiestler B, Capper D, Holland-Letz T, Deimling Av, Pfister SM, Platten M, Weller M, Wick W. Abstract LB-80: ATRX loss refines the classification of anaplastic glioma and is a favorable prognostic marker. Cancer Research. 73. DOI: 10.1158/1538-7445.Am2013-Lb-80  0.389
2012 Platten M, Weller M, Wick W. Shaping the glioma immune microenvironment through tryptophan metabolism. Cns Oncology. 1: 99-106. PMID 25054303 DOI: 10.2217/Cns.12.6  0.396
2012 Platten M, Wick W, Van den Eynde BJ. Tryptophan catabolism in cancer: beyond IDO and tryptophan depletion. Cancer Research. 72: 5435-40. PMID 23090118 DOI: 10.1158/0008-5472.Can-12-0569  0.388
2012 Ott M, Litzenburger UM, Sahm F, Rauschenbach KJ, Tudoran R, Hartmann C, Marquez VE, von Deimling A, Wick W, Platten M. Promotion of glioblastoma cell motility by enhancer of zeste homolog 2 (EZH2) is mediated by AXL receptor kinase. Plos One. 7: e47663. PMID 23077658 DOI: 10.1371/journal.pone.0047663  0.451
2012 Platten M, Wick W. [Treatment of brain tumor patients: hyperthermia, hyperbaric oxygenation, electric fields or nanoparticles]. Der Nervenarzt. 83: 982-7. PMID 22801663 DOI: 10.1007/S00115-012-3569-7  0.35
2011 Opitz CA, Litzenburger UM, Opitz U, Sahm F, Ochs K, Lutz C, Wick W, Platten M. The indoleamine-2,3-dioxygenase (IDO) inhibitor 1-methyl-D-tryptophan upregulates IDO1 in human cancer cells. Plos One. 6: e19823. PMID 21625531 DOI: 10.1371/Journal.Pone.0019823  0.352
2011 Seidel C, Dörner N, Osswald M, Wick A, Platten M, Bendszus M, Wick W. Does age matter? - A MRI study on peritumoral edema in newly diagnosed primary glioblastoma. Bmc Cancer. 11: 127. PMID 21481277 DOI: 10.1186/1471-2407-11-127  0.376
2010 Platten M, Dörner N, Hofer S, Schäfer N, Schemmer D, Weller M, Bendszus M, Wick W, Wick A. Evaluation of distant spread in bevacizumab-treated versus control-treated patients with malignant gliomas: A matched-pair study. Journal of Clinical Oncology. 28: 2064-2064. DOI: 10.1200/Jco.2010.28.15_Suppl.2064  0.397
2009 Platten M, Youssef S, Hur EM, Ho PP, Han MH, Lanz TV, Phillips LK, Goldstein MJ, Bhat R, Raine CS, Sobel RA, Steinman L. Blocking angiotensin-converting enzyme induces potent regulatory T cells and modulates TH1- and TH17-mediated autoimmunity. Proceedings of the National Academy of Sciences of the United States of America. 106: 14948-53. PMID 19706421 DOI: 10.1073/Pnas.0903958106  0.315
2009 Combs SE, Hartmann C, Welzel J, von Deimling A, Debus J, Platten M, Wick W, Gaiser T. Influence of expression of EGFR and PTEN on outcome in patients with primary glioblastoma treated with standard radiochemotherapy and cetuximab: Interim analysis from the GERT-Protocol Journal of Clinical Oncology. 27: 2050-2050. DOI: 10.1200/Jco.2009.27.15_Suppl.2050  0.327
2009 Platten M. Tumorprogress versus therapieinduzierte Veränderungen (Pseudoprogression) bei malignen Astrozytomen Onkopipeline. 2: 16-18. DOI: 10.1007/S15035-009-0139-Y  0.367
2008 Combs SE, Schulz-Ertner D, Hartmann C, Welzel T, Timke C, Herfarth K, von Deimling A, Edler L, Platten M, Wick W, Debus J. Phase I/II study of cetuximab plus temozolomide as radiochemotherapy for primary glioblastoma (GERT)—Eudract number 2005–003911–63; NCT00311857 Journal of Clinical Oncology. 26: 2077-2077. DOI: 10.1200/Jco.2008.26.15_Suppl.2077  0.311
2007 Wick A, Felsberg J, Steinbach JP, Herrlinger U, Platten M, Blaschke B, Meyermann R, Reifenberger G, Weller M, Wick W. Efficacy and tolerability of temozolomide in an alternating weekly regimen in patients with recurrent glioma. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 25: 3357-61. PMID 17664483 DOI: 10.1200/Jco.2007.10.7722  0.338
2007 Wick W, Wick A, Schuth J, Platten M, Reifenberger G, Weller M. One week on/one week off regimen of temozolomide: Phase II trial in recurrent glioma Journal of Clinical Oncology. 25: 2032-2032. DOI: 10.1200/Jco.2007.25.18_Suppl.2032  0.334
2005 Platten M, Ho PP, Youssef S, Fontoura P, Garren H, Hur EM, Gupta R, Lee LY, Kidd BA, Robinson WH, Sobel RA, Selley ML, Steinman L. Treatment of autoimmune neuroinflammation with a synthetic tryptophan metabolite. Science (New York, N.Y.). 310: 850-5. PMID 16272121 DOI: 10.1126/Science.1117634  0.301
2000 Roth W, Wild-Bode C, Platten M, Grimmel C, Melkonyan HS, Dichgans J, Weller M. Secreted Frizzled-related proteins inhibit motility and promote growth of human malignant glioma cells. Oncogene. 19: 4210-20. PMID 10980594 DOI: 10.1038/Sj.Onc.1203783  0.355
1997 Platten M, Meyer-Puttlitz B, Blümcke I, Waha A, Wolf HK, Nöthen MM, Louis DN, Sampson JR, von Deimling A. A novel splice site associated polymorphism in the tuberous sclerosis 2 (TSC2) gene may predispose to the development of sporadic gangliogliomas. Journal of Neuropathology and Experimental Neurology. 56: 806-10. PMID 9210877 DOI: 10.1097/00005072-199756070-00007  0.519
1996 Platten M, Giordano MJ, Dirven CM, Gutmann DH, Louis DN. Up-regulation of specific NF 1 gene transcripts in sporadic pilocytic astrocytomas. The American Journal of Pathology. 149: 621-7. PMID 8702000  0.427
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