Lorraine J. Gudas - Publications

Affiliations: 
Neuroscience Weill Cornell Medical College, New York, NY, United States 
Area:
Cell Biology, Molecular Biology, Genetics, Biochemistry

206 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Lothion-Roy J, Haigh DB, Harris AE, Metzler VM, Alsaleem M, Toss MS, Kariri Y, Ntekim A, Robinson BD, Khani F, Gudas LJ, Allegrucci C, James VH, Madhusudan S, Mather M, et al. Clinical and molecular significance of the RNA mA methyltransferase complex in prostate cancer. Frontiers in Genetics. 13: 1096071. PMID 36733939 DOI: 10.3389/fgene.2022.1096071  0.302
2020 Marta M, Zhang T, Scognamiglio T, Gudas LJ. Mutations in long-lived epithelial stem cells and their clonal progeny in pre-malignant lesions and in oral squamous cell carcinoma. Carcinogenesis. PMID 32115621 DOI: 10.1093/Carcin/Bgaa019  0.386
2020 Kalish JM, Tang XH, Scognamiglio T, Zhang T, Gudas LJ. Doxycycline-induced exogenous Bmi-1 expression enhances tumor formation in a murine model of oral squamous cell carcinoma. Cancer Biology & Therapy. 1-12. PMID 32037955 DOI: 10.1080/15384047.2020.1720485  0.409
2019 van der Mijn JC, Fu L, Khani F, Zhang T, Molina AM, Barbieri CE, Chen Q, Gross SS, Gudas LJ, Nanus DM. Combined Metabolomics and Genome-Wide Transcriptomics Analyses Show Multiple HIF1α-Induced Changes in Lipid Metabolism in Early Stage Clear Cell Renal Cell Carcinoma. Translational Oncology. 13: 177-185. PMID 31865180 DOI: 10.1016/J.Tranon.2019.10.015  0.331
2019 Serio RN, Gudas LJ. Modification of stem cell states by alcohol and acetaldehyde. Chemico-Biological Interactions. 316: 108919. PMID 31846616 DOI: 10.1016/J.Cbi.2019.108919  0.44
2019 Orfali N, Shan-Krauer D, O'Donovan TR, Mongan NP, Gudas LJ, Cahill MR, Tschan MP, McKenna SL. Inhibition of UBE2L6 attenuates ISGylation and impedes ATRA-induced differentiation of leukemic cells. Molecular Oncology. PMID 31820845 DOI: 10.1002/1878-0261.12614  0.486
2019 Orfali N, O'Donovan TR, Cahill MR, Benjamin D, Nanus DM, McKenna SL, Gudas LJ, Mongan NP. All-trans retinoic acid (ATRA) induced TFEB expression is required for myeloid differentiation in acute promyelocytic leukemia (APL). European Journal of Haematology. PMID 31811682 DOI: 10.1111/Ejh.13367  0.393
2019 Orfali N, Jeyapalan JN, Woodcock CL, O'Donovan TR, Benjamin D, Cahill M, McKenna S, Gudas LJ, Mongan NP. Lentiviral-Mediated shRNA Approaches: Applications in Cellular Differentiation and Autophagy. Methods in Molecular Biology (Clifton, N.J.). 2019: 33-49. PMID 31359387 DOI: 10.1007/978-1-4939-9585-1_3  0.419
2019 Serio RN, Lu C, Gross SS, Gudas LJ. Different effects of knockouts in ALDH2 and ACSS2 on embryonic stem cell differentiation. Alcoholism, Clinical and Experimental Research. PMID 31283017 DOI: 10.1111/Acer.14146  0.405
2019 Osei-Sarfo K, Gudas LJ. Retinoids induce antagonism between FOXO3A and FOXM1 transcription factors in human oral squamous cell carcinoma (OSCC) cells. Plos One. 14: e0215234. PMID 30978209 DOI: 10.1371/Journal.Pone.0215234  0.485
2019 Serio RN, Laursen KB, Urvalek AM, Gross SS, Gudas LJ. Ethanol promotes differentiation of embryonic stem cells through retinoic acid receptor-γ. The Journal of Biological Chemistry. PMID 30737277 DOI: 10.1074/Jbc.Ra118.007153  0.501
2019 Melis M, Zhang T, Scognamiglio T, Gudas LJ. Abstract 4665: Lineage-tracing technology to understand the molecular events in a mouse model of tongue squamous cell carcinoma (SCC) carcinogenesis Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-4665  0.315
2018 Quintero CM, Laursen KB, Mongan NP, Luo M, Gudas LJ. CARM1 (PRMT4) Acts as a Transcriptional Coactivator during Retinoic Acid-Induced Embryonic Stem Cell Differentiation. Journal of Molecular Biology. PMID 30153436 DOI: 10.1016/J.Jmb.2018.08.014  0.458
2018 Laursen KB, Gudas LJ. Combinatorial knockout of RARα, RARβ, and RARγ completely abrogates transcriptional responses to retinoic acid in murine embryonic stem cells. The Journal of Biological Chemistry. PMID 29848550 DOI: 10.1074/Jbc.Ra118.001951  0.471
2016 Simandi Z, Horvath A, Wright LC, Cuaranta-Monroy I, De Luca I, Karolyi K, Sauer S, Deleuze JF, Gudas LJ, Cowley SM, Nagy L. OCT4 Acts as an Integrator of Pluripotency and Signal-Induced Differentiation. Molecular Cell. PMID 27499297 DOI: 10.1016/J.Molcel.2016.06.039  0.429
2016 Trasino SE, Tang XH, Jessurun J, Gudas LJ. A retinoic acid receptor β2 agonist reduces hepatic stellate cell activation in nonalcoholic fatty liver disease. Journal of Molecular Medicine (Berlin, Germany). PMID 27271256 DOI: 10.1007/S00109-016-1434-Z  0.322
2016 Minton DR, Fu L, Mongan NP, Shevchuk MM, Nanus DM, Gudas LJ. Role of NADH Dehydrogenase (Ubiquinone) 1 alpha subcomplex 4-like 2 in clear cell renal cell carcinoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 26783287 DOI: 10.1158/1078-0432.Ccr-15-1511  0.343
2016 Nanus DM, Gudas LJ. The Tale of Two Hypoxia-Inducible Factors in Renal Cell Carcinoma. European Urology. 69: 658-9. PMID 26431912 DOI: 10.1016/J.Eururo.2015.09.020  0.373
2015 Nilsson EM, Laursen KB, Whitchurch J, McWilliam A, Ødum N, Persson JL, Heery DM, Gudas LJ, Mongan NP. MIR137 is an androgen regulated repressor of an extended network of transcriptional coregulators. Oncotarget. PMID 26461474 DOI: 10.18632/Oncotarget.5958  0.313
2015 Tang XH, Urvalek AM, Osei-Sarfo K, Zhang T, Scognamiglio T, Gudas LJ. Gene expression profiling signatures for the diagnosis and prevention of oral cavity carcinogenesis-genome-wide analysis using RNA-seq technology. Oncotarget. PMID 26110572 DOI: 10.18632/Oncotarget.4420  0.385
2015 Orfali N, O'Donovan TR, Nyhan MJ, Britschgi A, Tschan MP, Cahill MR, Mongan NP, Gudas LJ, McKenna SL. Induction of autophagy is a key component of all-trans-retinoic acid-induced differentiation in leukemia cells and a potential target for pharmacologic modulation. Experimental Hematology. PMID 25986473 DOI: 10.1016/J.Exphem.2015.04.012  0.432
2015 Minton DR, Fu L, Chen Q, Robinson BD, Gross SS, Nanus DM, Gudas LJ. Analyses of the transcriptome and metabolome demonstrate that HIF1α mediates altered tumor metabolism in clear cell renal cell carcinoma. Plos One. 10: e0120649. PMID 25830305 DOI: 10.1371/Journal.Pone.0120649  0.379
2015 Fu L, Minton DR, Zhang T, Nanus DM, Gudas LJ. Genome-Wide Profiling of TRACK Kidneys Shows Similarity to the Human ccRCC Transcriptome. Molecular Cancer Research : McR. 13: 870-8. PMID 25715653 DOI: 10.1158/1541-7786.Mcr-14-0423  0.381
2015 Osei-Sarfo K, Urvalek AM, Tang XH, Scognamiglio T, Gudas LJ. Initiation of esophageal squamous cell carcinoma (ESCC) in a murine 4-nitroquinoline-1-oxide and alcohol carcinogenesis model. Oncotarget. 6: 6040-52. PMID 25714027 DOI: 10.18632/Oncotarget.3339  0.33
2015 Laursen KB, Kashyap V, Scandura J, Gudas LJ. An alternative retinoic acid-responsive Stra6 promoter regulated in response to retinol deficiency. The Journal of Biological Chemistry. 290: 4356-66. PMID 25544292 DOI: 10.1074/Jbc.M114.613968  0.449
2015 Trasino SE, Benoit YD, Gudas LJ. Vitamin A deficiency causes hyperglycemia and loss of pancreatic β-cell mass. The Journal of Biological Chemistry. 290: 1456-73. PMID 25451926 DOI: 10.1074/Jbc.M114.616763  0.333
2014 Urvalek A, Laursen KB, Gudas LJ. The roles of retinoic acid and retinoic acid receptors in inducing epigenetic changes. Sub-Cellular Biochemistry. 70: 129-49. PMID 24962884 DOI: 10.1007/978-94-017-9050-5_7  0.364
2014 Gudas LJ, Fu L, Minton DR, Mongan NP, Nanus DM. The role of HIF1α in renal cell carcinoma tumorigenesis. Journal of Molecular Medicine (Berlin, Germany). 92: 825-36. PMID 24916472 DOI: 10.1007/S00109-014-1180-Z  0.373
2014 Laursen KB, Gudas LJ. Crossing the barrier: STRA6 in epidermal differentiation. The Journal of Investigative Dermatology. 134: 1504-6. PMID 24825059 DOI: 10.1038/Jid.2014.49  0.309
2014 Urvalek AM, Gudas LJ. Retinoic acid and histone deacetylases regulate epigenetic changes in embryonic stem cells. The Journal of Biological Chemistry. 289: 19519-30. PMID 24821725 DOI: 10.1074/Jbc.M114.556555  0.466
2014 Orfali N, McKenna SL, Cahill MR, Gudas LJ, Mongan NP. Retinoid receptor signaling and autophagy in acute promyelocytic leukemia. Experimental Cell Research. 324: 1-12. PMID 24694321 DOI: 10.1016/J.Yexcr.2014.03.018  0.404
2014 Osei-Sarfo K, Gudas LJ. Retinoic acid suppresses the canonical Wnt signaling pathway in embryonic stem cells and activates the noncanonical Wnt signaling pathway. Stem Cells (Dayton, Ohio). 32: 2061-71. PMID 24648413 DOI: 10.1002/Stem.1706  0.402
2014 Marcinkiewicz KM, Gudas LJ. Altered histone mark deposition and DNA methylation at homeobox genes in human oral squamous cell carcinoma. Journal of Cellular Physiology. 229: 1405-16. PMID 24519855 DOI: 10.1002/Jcp.24577  0.769
2014 Marcinkiewicz KM, Gudas LJ. Altered epigenetic regulation of homeobox genes in human oral squamous cell carcinoma cells. Experimental Cell Research. 320: 128-43. PMID 24076275 DOI: 10.1016/J.Yexcr.2013.09.011  0.804
2014 Orfali NM, Mongan NP, Cahill MR, McKenna SL, Gudas LJ. ATRA-Induced Activation of the Autophagy Regulator Tfeb Regulates Myeloid Differentiation in Acute Promyelocytic Leukemia Blood. 124: 1057-1057. DOI: 10.1182/Blood.V124.21.1057.1057  0.452
2014 Tang X, Scognamiglio T, Gudas L. Abstract 3036: Basal stem cells contribute to squamous cell carcinomas in the oral cavity Cancer Research. 74: 3036-3036. DOI: 10.1158/1538-7445.Am2014-3036  0.42
2013 Gudas LJ. Retinoids induce stem cell differentiation via epigenetic changes. Seminars in Cell & Developmental Biology. 24: 701-5. PMID 23973942 DOI: 10.1016/J.Semcdb.2013.08.002  0.476
2013 Ricard MJ, Gudas LJ. Cytochrome p450 cyp26a1 alters spinal motor neuron subtype identity in differentiating embryonic stem cells. The Journal of Biological Chemistry. 288: 28801-13. PMID 23946489 DOI: 10.1074/Jbc.M113.474254  0.782
2013 Osei-Sarfo K, Tang XH, Urvalek AM, Scognamiglio T, Gudas LJ. The molecular features of tongue epithelium treated with the carcinogen 4-nitroquinoline-1-oxide and alcohol as a model for HNSCC. Carcinogenesis. 34: 2673-81. PMID 23784083 DOI: 10.1093/Carcin/Bgt223  0.372
2013 Pérez RJ, Benoit YD, Gudas LJ. Deletion of retinoic acid receptor β (RARβ) impairs pancreatic endocrine differentiation. Experimental Cell Research. 319: 2196-204. PMID 23756134 DOI: 10.1016/J.Yexcr.2013.05.032  0.457
2013 Laursen KB, Mongan NP, Zhuang Y, Ng MM, Benoit YD, Gudas LJ. Polycomb recruitment attenuates retinoic acid-induced transcription of the bivalent NR2F1 gene. Nucleic Acids Research. 41: 6430-43. PMID 23666625 DOI: 10.1093/Nar/Gkt367  0.452
2013 Kauffman EC, Robinson BD, Downes M, Marcinkiewicz K, Vourganti S, Scherr DS, Gudas LJ, Mongan NP. Estrogen receptor-β expression and pharmacological targeting in bladder cancer. Oncology Reports. 30: 131-8. PMID 23612777 DOI: 10.3892/Or.2013.2416  0.746
2013 Benoit YD, Witherspoon MS, Laursen KB, Guezguez A, Beauséjour M, Beaulieu JF, Lipkin SM, Gudas LJ. Pharmacological inhibition of polycomb repressive complex-2 activity induces apoptosis in human colon cancer stem cells. Experimental Cell Research. 319: 1463-70. PMID 23588203 DOI: 10.1016/J.Yexcr.2013.04.006  0.433
2013 Hedblom A, Laursen KB, Miftakhova R, Sarwar M, Anagnostaki L, Bredberg A, Mongan NP, Gudas LJ, Persson JL. CDK1 interacts with RARγ and plays an important role in treatment response of acute myeloid leukemia. Cell Cycle (Georgetown, Tex.). 12: 1251-66. PMID 23518499 DOI: 10.4161/Cc.24313  0.355
2013 Fu L, Wang G, Shevchuk MM, Nanus DM, Gudas LJ. Activation of HIF2α in kidney proximal tubule cells causes abnormal glycogen deposition but not tumorigenesis. Cancer Research. 73: 2916-25. PMID 23447580 DOI: 10.1158/0008-5472.Can-12-3983  0.377
2013 Kashyap V, Ahmad S, Nilsson EM, Helczynski L, Kenna S, Persson JL, Gudas LJ, Mongan NP. The lysine specific demethylase-1 (LSD1/KDM1A) regulates VEGF-A expression in prostate cancer. Molecular Oncology. 7: 555-66. PMID 23384557 DOI: 10.1016/J.Molonc.2013.01.003  0.371
2013 Tang XH, Scognamiglio T, Gudas LJ. Basal stem cells contribute to squamous cell carcinomas in the oral cavity. Carcinogenesis. 34: 1158-64. PMID 23358851 DOI: 10.1093/Carcin/Bgt021  0.408
2013 Kashyap V, Laursen KB, Brenet F, Viale AJ, Scandura JM, Gudas LJ. RARγ is essential for retinoic acid induced chromatin remodeling and transcriptional activation in embryonic stem cells. Journal of Cell Science. 126: 999-1008. PMID 23264745 DOI: 10.1242/Jcs.119701  0.495
2013 Benoit YD, Laursen KB, Witherspoon MS, Lipkin SM, Gudas LJ. Inhibition of PRC2 histone methyltransferase activity increases TRAIL-mediated apoptosis sensitivity in human colon cancer cells. Journal of Cellular Physiology. 228: 764-72. PMID 23001792 DOI: 10.1002/Jcp.24224  0.434
2013 Joseph C, Hendy J, Fabb SA, Baker EK, Chalk AM, Walkley CR, Gudas LJ, Wall M, Purton LE. Modeling Myelodysplastic Syndromes In Mice By Altered Hoxa1 Spliceform Expression Blood. 122: 97-97. DOI: 10.1182/Blood.V122.21.97.97  0.352
2013 Marcinkiewicz KM, Gudas LJ. Abstract A27: Altered epigenetic regulation of homeobox genes in human oral squamous cell carcinoma cells Cancer Research. 73. DOI: 10.1158/1538-7445.Cec13-A27  0.797
2012 Benoit YD, Lepage MB, Khalfaoui T, Tremblay E, Basora N, Carrier JC, Gudas LJ, Beaulieu JF. Polycomb repressive complex 2 impedes intestinal cell terminal differentiation. Journal of Cell Science. 125: 3454-63. PMID 22467857 DOI: 10.1242/Jcs.102061  0.483
2012 Marcinkiewicz K, Scotland KB, Boorjian SA, Nilsson EM, Persson JL, Abrahamsson PA, Allegrucci C, Hughes IA, Gudas LJ, Mongan NP. The androgen receptor and stem cell pathways in prostate and bladder cancers (review). International Journal of Oncology. 40: 5-12. PMID 21956088 DOI: 10.3892/Ijo.2011.1212  0.785
2012 Laursen KB, Wong PM, Gudas LJ. Epigenetic regulation by RARα maintains ligand-independent transcriptional activity. Nucleic Acids Research. 40: 102-15. PMID 21911359 DOI: 10.1093/Nar/Gkr637  0.457
2012 Gudas LJ. Emerging roles for retinoids in regeneration and differentiation in normal and disease states. Biochimica Et Biophysica Acta. 1821: 213-21. PMID 21855651 DOI: 10.1016/J.Bbalip.2011.08.002  0.43
2012 Orfali NM, O'Donovan T, Nyhan M, Mongan NP, Gudas LJ, Cahill MR, McKenna S. Autophagy As a Target for Differentiation Therapy in Acute Myeloid Leukemia. Blood. 120: 2464-2464. DOI: 10.1182/Blood.V120.21.2464.2464  0.427
2012 Fu L, Wang G, Shevchuk MM, Nanus DM, Gudas LJ. Abstract LB-486: Overexpression of a mutated, constitutively active HIF2α promotes the carcinogenesis of TRACK mouse Cancer Research. 72. DOI: 10.1158/1538-7445.Am2012-Lb-486  0.395
2012 Kauffman E, Robinson B, Downes M, Marcinkiewicz K, Powell L, Lee MM, Scherr D, Gudas L, Mongan N. 895 ESTROGEN RECEPTOR BETA EXPRESSION AND PHARMACOLOGIC TARGETING IN TRANSITIONAL CELL CARCINOMA OF THE BLADDER Journal of Urology. 187. DOI: 10.1016/J.Juro.2012.02.990  0.737
2011 Fu L, Wang G, Shevchuk MM, Nanus DM, Gudas LJ. Generation of a mouse model of Von Hippel-Lindau kidney disease leading to renal cancers by expression of a constitutively active mutant of HIF1α. Cancer Research. 71: 6848-56. PMID 21908555 DOI: 10.1158/0008-5472.Can-11-1745  0.379
2011 Larsson R, Mongan NP, Johansson M, Shcherbina L, Abrahamsson PA, Gudas LJ, Sterner O, Persson JL. Clinical trial update and novel therapeutic approaches for metastatic prostate cancer. Current Medicinal Chemistry. 18: 4440-53. PMID 21864277 DOI: 10.2174/092986711797287539  0.321
2011 Rezende NC, Lee MY, Monette S, Mark W, Lu A, Gudas LJ. Rex1 (Zfp42) null mice show impaired testicular function, abnormal testis morphology, and aberrant gene expression. Developmental Biology. 356: 370-82. PMID 21641340 DOI: 10.1016/J.Ydbio.2011.05.664  0.791
2011 Kauffman EC, Robinson BD, Downes MJ, Powell LG, Lee MM, Scherr DS, Gudas LJ, Mongan NP. Role of androgen receptor and associated lysine-demethylase coregulators, LSD1 and JMJD2A, in localized and advanced human bladder cancer. Molecular Carcinogenesis. 50: 931-44. PMID 21400613 DOI: 10.1002/Mc.20758  0.389
2011 Kashyap V, Gudas LJ, Brenet F, Funk P, Viale A, Scandura JM. Epigenomic reorganization of the clustered Hox genes in embryonic stem cells induced by retinoic acid. The Journal of Biological Chemistry. 286: 3250-60. PMID 21087926 DOI: 10.1074/Jbc.M110.157545  0.428
2011 Tang XH, Gudas LJ. Retinoids, retinoic acid receptors, and cancer. Annual Review of Pathology. 6: 345-64. PMID 21073338 DOI: 10.1146/Annurev-Pathol-011110-130303  0.392
2011 Reynertson KA, Charlson ME, Gudas LJ. Induction of murine embryonic stem cell differentiation by medicinal plant extracts. Experimental Cell Research. 317: 82-93. PMID 20955699 DOI: 10.1016/J.Yexcr.2010.10.010  0.42
2011 Amat R, Gudas LJ. RARγ is required for correct deposition and removal of Suz12 and H2A.Z in embryonic stem cells. Journal of Cellular Physiology. 226: 293-8. PMID 20857416 DOI: 10.1002/Jcp.22420  0.456
2011 Gudas LJ, Wagner JA. Retinoids regulate stem cell differentiation Journal of Cellular Physiology. 226: 322-330. PMID 20836077 DOI: 10.1002/Jcp.22417  0.486
2011 Nanus DM, Tagawa ST, Dutcher JP, Akhtar NH, Saran A, Mazumdar M, Milowsky MI, Gudas LJ. NCI 6896: A phase I trial of suberoylanilide hydroxamic acid (SAHA) and 13-cis retinoic acid in the treatment of patients with advanced renal cell carcinoma (RCC). Journal of Clinical Oncology. 29: 349-349. DOI: 10.1200/Jco.2011.29.7_Suppl.349  0.344
2011 Hedblom A, Laursen KB, Miftakhova RR, Sarwar M, Mongan NP, Gudas LJ, Persson JL. The Functional Link Between CDK1 and Retinoic Acid Receptor γ (RARγ) in Response to Treatment with All-Trans Retinoic Acid Blood. 118: 2485-2485. DOI: 10.1182/Blood.V118.21.2485.2485  0.426
2011 Hendy J, Fabb SA, Wall M, Gudas LJ, McArthur GA, Purton LE. Deregulated Hoxa1 Expression in Murine Bone Marrow Results in An MDS-Like Phenotype Blood. 118: 2423-2423. DOI: 10.1182/Blood.V118.21.2423.2423  0.333
2011 Fu L, Wang E, Shevchuk MM, Nanus DM, Gudas LJ. Abstract 2857: Expression of mutated, constitutively active HIF1α in the mouse kidney results in early stage clear cell renal cell carcinoma Cancer Research. 71: 2857-2857. DOI: 10.1158/1538-7445.Am2011-2857  0.431
2011 Tang X, Gudas L. Abstract 1338: MicroRNAs in a mouse model of oral carcinogenesis Cancer Research. 71: 1338-1338. DOI: 10.1158/1538-7445.Am2011-1338  0.335
2010 Wang R, Wang G, Ricard MJ, Ferris B, Strulovici-Barel Y, Salit J, Hackett NR, Gudas LJ, Crystal RG. Smoking-induced upregulation of AKR1B10 expression in the airway epithelium of healthy individuals. Chest. 138: 1402-10. PMID 20705797 DOI: 10.1378/Chest.09-2634  0.758
2010 Lee MY, Lu A, Gudas LJ. Transcriptional regulation of Rex1 (zfp42) in normal prostate epithelial cells and prostate cancer cells. Journal of Cellular Physiology. 224: 17-27. PMID 20232320 DOI: 10.1002/Jcp.22071  0.465
2010 Kashyap V, Gudas LJ. Epigenetic regulatory mechanisms distinguish retinoic acid-mediated transcriptional responses in stem cells and fibroblasts. The Journal of Biological Chemistry. 285: 14534-48. PMID 20231276 DOI: 10.1074/Jbc.M110.115345  0.461
2010 Wang G, Badylak SF, Heber-Katz E, Braunhut SJ, Gudas LJ. The effects of DNA methyltransferase inhibitors and histone deacetylase inhibitors on digit regeneration in mice. Regenerative Medicine. 5: 201-20. PMID 20210581 DOI: 10.2217/Rme.09.91  0.394
2010 David KA, Mongan NP, Smith C, Gudas LJ, Nanus DM. Phase I trial of ATRA-IV and Depakote in patients with advanced solid tumor malignancies. Cancer Biology & Therapy. 9: 678-84. PMID 20200483 DOI: 10.4161/Cbt.9.9.11436  0.361
2010 Agrawal V, Johnson SA, Reing J, Zhang L, Tottey S, Wang G, Hirschi KK, Braunhut S, Gudas LJ, Badylak SF. Epimorphic regeneration approach to tissue replacement in adult mammals. Proceedings of the National Academy of Sciences of the United States of America. 107: 3351-5. PMID 19966310 DOI: 10.1073/Pnas.0905851106  0.379
2010 Liu L, Tang XH, Scognamiglio T, Gudas LJ. Oral carcinogenesis induced by 4-nitroquinoline 1-oxide in lecithin:retinol acyltransferase gene knockout mice. The Journal of Nutritional Biochemistry. 21: 975-82. PMID 19954945 DOI: 10.1016/J.Jnutbio.2009.07.012  0.405
2009 Tang XH, Albert M, Scognamiglio T, Gudas LJ. A DNA methyltransferase inhibitor and all-trans retinoic acid reduce oral cavity carcinogenesis induced by the carcinogen 4-nitroquinoline 1-oxide. Cancer Prevention Research (Philadelphia, Pa.). 2: 1100-10. PMID 19952362 DOI: 10.1158/1940-6207.Capr-09-0136  0.386
2009 Scotland KB, Chen S, Sylvester R, Gudas LJ. Analysis of Rex1 (zfp42) function in embryonic stem cell differentiation. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 238: 1863-77. PMID 19618472 DOI: 10.1002/Dvdy.22037  0.745
2009 Touma SE, Perner S, Rubin MA, Nanus DM, Gudas LJ. Retinoid metabolism and ALDH1A2 (RALDH2) expression are altered in the transgenic adenocarcinoma mouse prostate model. Biochemical Pharmacology. 78: 1127-38. PMID 19549509 DOI: 10.1016/J.Bcp.2009.06.022  0.741
2009 Liu L, Derguini F, Gudas LJ. Metabolism and regulation of gene expression by 4-oxoretinol versus all-trans retinoic acid in normal human mammary epithelial cells. Journal of Cellular Physiology. 220: 771-9. PMID 19492420 DOI: 10.1002/Jcp.21824  0.47
2009 Kashyap V, Rezende NC, Scotland KB, Shaffer SM, Persson JL, Gudas LJ, Mongan NP. Regulation of stem cell pluripotency and differentiation involves a mutual regulatory circuit of the NANOG, OCT4, and SOX2 pluripotency transcription factors with polycomb repressive complexes and stem cell microRNAs. Stem Cells and Development. 18: 1093-108. PMID 19480567 DOI: 10.1089/Scd.2009.0113  0.763
2009 Tang XH, Su D, Albert M, Scognamiglio T, Gudas LJ. Overexpression of lecithin:retinol acyltransferase in the epithelial basal layer makes mice more sensitive to oral cavity carcinogenesis induced by a carcinogen. Cancer Biology & Therapy. 8: 1212-3. PMID 19471114 DOI: 10.4161/Cbt.8.13.8630  0.348
2009 Schupp M, Lefterova MI, Janke J, Leitner K, Cristancho AG, Mullican SE, Qatanani M, Szwergold N, Steger DJ, Curtin JC, Kim RJ, Suh MJ, Suh M, Albert MR, Engeli S, ... Gudas LJ, et al. Retinol saturase promotes adipogenesis and is downregulated in obesity. Proceedings of the National Academy of Sciences of the United States of America. 106: 1105-10. PMID 19139408 DOI: 10.1073/Pnas.0812065106  0.345
2009 Fernandez CC, Gudas LJ. The truncated Hoxa1 protein interacts with Hoxa1 and Pbx1 in stem cells. Journal of Cellular Biochemistry. 106: 427-43. PMID 19115252 DOI: 10.1002/Jcb.22023  0.602
2009 Cai K, Gudas LJ. Retinoic acid receptors and GATA transcription factors activate the transcription of the human lecithin:retinol acyltransferase gene. The International Journal of Biochemistry & Cell Biology. 41: 546-53. PMID 18652909 DOI: 10.1016/J.Biocel.2008.06.007  0.485
2009 Hendy J, Fabb SA, Wall M, Simmons PJ, Gudas LJ, McArthur GA, Purton LE. The Truncated Form of Hoxa1 Regulates Proliferation and Differentiation of Hematopoietic Stem and Progenitor Cells. Blood. 114: 3654-3654. DOI: 10.1182/Blood.V114.22.3654.3654  0.403
2008 Tavares TS, Nanus D, Yang XJ, Gudas LJ. Gene microarray analysis of human renal cell carcinoma: the effects of HDAC inhibition and retinoid treatment. Cancer Biology & Therapy. 7: 1607-18. PMID 18769122 DOI: 10.4161/Cbt.7.10.6584  0.464
2008 Martinez-Ceballos E, Gudas LJ. Hoxa1 is required for the retinoic acid-induced differentiation of embryonic stem cells into neurons. Journal of Neuroscience Research. 86: 2809-19. PMID 18512762 DOI: 10.1002/Jnr.21729  0.817
2008 Liu L, Tang XH, Gudas LJ. Homeostasis of retinol in lecithin: retinol acyltransferase gene knockout mice fed a high retinol diet. Biochemical Pharmacology. 75: 2316-24. PMID 18455147 DOI: 10.1016/J.Bcp.2008.03.012  0.302
2008 Su D, Gudas LJ. Retinoic acid receptor gamma activates receptor tyrosine kinase Tie1 gene transcription through transcription factor GATA4 in F9 stem cells. Experimental Hematology. 36: 624-41. PMID 18439490 DOI: 10.1016/J.Exphem.2007.12.016  0.457
2008 Langton S, Gudas LJ. CYP26A1 knockout embryonic stem cells exhibit reduced differentiation and growth arrest in response to retinoic acid. Developmental Biology. 315: 331-54. PMID 18241852 DOI: 10.1016/J.Ydbio.2007.12.021  0.67
2008 Xu J, Sylvester R, Tighe AP, Chen S, Gudas LJ. Transcriptional activation of the suppressor of cytokine signaling-3 (SOCS-3) gene via STAT3 is increased in F9 REX1 (ZFP-42) knockout teratocarcinoma stem cells relative to wild-type cells. Journal of Molecular Biology. 377: 28-46. PMID 18237746 DOI: 10.1016/J.Jmb.2007.12.038  0.663
2008 Zhuang Y, Gudas LJ. Overexpression of COUP-TF1 in murine embryonic stem cells reduces retinoic acid-associated growth arrest and increases extraembryonic endoderm gene expression. Differentiation; Research in Biological Diversity. 76: 760-71. PMID 18177425 DOI: 10.1111/J.1432-0436.2007.00258.X  0.499
2008 Su D, Gudas LJ. Gene expression profiling elucidates a specific role for RARgamma in the retinoic acid-induced differentiation of F9 teratocarcinoma stem cells. Biochemical Pharmacology. 75: 1129-60. PMID 18164278 DOI: 10.1016/J.Bcp.2007.11.006  0.479
2008 Lane MA, Xu J, Wilen EW, Sylvester R, Derguini F, Gudas LJ. LIF removal increases CRABPI and CRABPII transcripts in embryonic stem cells cultured in retinol or 4-oxoretinol. Molecular and Cellular Endocrinology. 280: 63-74. PMID 18006143 DOI: 10.1016/J.Mce.2007.09.010  0.636
2008 Tang XH, Vivero M, Gudas LJ. Overexpression of CRABPI in suprabasal keratinocytes enhances the proliferation of epidermal basal keratinocytes in mouse skin topically treated with all-trans retinoic acid. Experimental Cell Research. 314: 38-51. PMID 17727842 DOI: 10.1016/J.Yexcr.2007.07.016  0.331
2007 Gillespie RF, Gudas LJ. Retinoic acid receptor isotype specificity in F9 teratocarcinoma stem cells results from the differential recruitment of coregulators to retinoic response elements. The Journal of Biological Chemistry. 282: 33421-34. PMID 17875646 DOI: 10.1074/Jbc.M704845200  0.765
2007 Boorjian SA, Milowsky MI, Kaplan J, Albert M, Cobham MV, Coll DM, Mongan NP, Shelton G, Petrylak D, Gudas LJ, Nanus DM. Phase 1/2 clinical trial of interferon α2b and weekly liposome-encapsulated all-trans retinoic acid in patients with advanced renal cell carcinoma Journal of Immunotherapy. 30: 655-662. PMID 17667529 DOI: 10.1097/Cji.0B013E31805449A8  0.326
2007 Gillespie RF, Gudas LJ. Retinoid regulated association of transcriptional co-regulators and the polycomb group protein SUZ12 with the retinoic acid response elements of Hoxa1, RARbeta(2), and Cyp26A1 in F9 embryonal carcinoma cells. Journal of Molecular Biology. 372: 298-316. PMID 17663992 DOI: 10.1016/J.Jmb.2007.06.079  0.753
2007 Mongan NP, Gudas LJ. Diverse actions of retinoid receptors in cancer prevention and treatment. Differentiation; Research in Biological Diversity. 75: 853-70. PMID 17634071 DOI: 10.1111/J.1432-0436.2007.00206.X  0.443
2007 Tang XH, Suh MJ, Li R, Gudas LJ. Cell proliferation inhibition and alterations in retinol esterification induced by phytanic acid and docosahexaenoic acid. Journal of Lipid Research. 48: 165-76. PMID 17068359 DOI: 10.1194/Jlr.M600419-Jlr200  0.407
2006 Sheren-Manoff M, Shin SJ, Su D, Bok D, Rando RR, Gudas LJ. Reduced lecithin:retinol acyltransferase expression in human breast cancer. International Journal of Oncology. 29: 1193-9. PMID 17016651 DOI: 10.3892/Ijo.29.5.1193  0.305
2006 Gudas LJ. Stem cells, differentiation and cancer: mentors, colleagues and academic administration. Cancer Biology & Therapy. 5: 1244-6. PMID 17012844 DOI: 10.4161/Cbt.5.9.3344  0.41
2006 Mongan NP, Martin KM, Gudas LJ. The putative human stem cell marker, Rex-1 (Zfp42): structural classification and expression in normal human epithelial and carcinoma cell cultures. Molecular Carcinogenesis. 45: 887-900. PMID 16865673 DOI: 10.1002/Mc.20186  0.46
2006 Raman JD, Mongan NP, Liu L, Tickoo SK, Nanus DM, Scherr DS, Gudas LJ. Decreased expression of the human stem cell marker, Rex-1 (zfp-42), in renal cell carcinoma. Carcinogenesis. 27: 499-507. PMID 16344273 DOI: 10.1093/Carcin/Bgi299  0.412
2006 Atieh DM, Milowsky MI, Cobham M, Kaplan J, Smith C, Gudas LJ, Nanus DM. Phase I trial of a histone deacetylase inhibitor (HDACI) and retinoid acid (RA) in patients (pts) with advanced solid tumor malignancies Journal of Clinical Oncology. 24: 13114-13114. DOI: 10.1200/Jco.2006.24.18_Suppl.13114  0.368
2006 Raman JD, Mongan NP, Tickoo SK, Boorjian SA, Scherr DS, Gudas LJ. 608: Increased Expression of the Polycomb Group Gene, EZH2, in Transitional Cell Carcinoma of the Bladder The Journal of Urology. 175: 196-197. DOI: 10.1016/S0022-5347(18)32854-4  0.378
2006 Raman JD, Mongan NP, Liu L, Tickoo SK, Nanus DM, Scherr DS, Gudas LJ. 380: Decreased Expression of the Human Stem Cell Marker, REX-1 (ZFP-42), in Renal Cell Carcinoma The Journal of Urology. 175: 124-125. DOI: 10.1016/S0022-5347(18)32636-3  0.424
2005 Raman JD, Mongan NP, Tickoo SK, Boorjian SA, Scherr DS, Gudas LJ. Increased expression of the polycomb group gene, EZH2, in transitional cell carcinoma of the bladder. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 11: 8570-6. PMID 16361539 DOI: 10.1158/1078-0432.Ccr-05-1047  0.423
2005 Touma SE, Goldberg JS, Moench P, Guo X, Tickoo SK, Gudas LJ, Nanus DM. Retinoic acid and the histone deacetylase inhibitor trichostatin a inhibit the proliferation of human renal cell carcinoma in a xenograft tumor model. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 11: 3558-66. PMID 15867260 DOI: 10.1158/1078-0432.Ccr-04-1155  0.77
2005 Mongan NP, Gudas LJ. Valproic acid, in combination with all-trans retinoic acid and 5-aza-2'-deoxycytidine, restores expression of silenced RARbeta2 in breast cancer cells. Molecular Cancer Therapeutics. 4: 477-86. PMID 15767557 DOI: 10.1158/1535-7163.Mct-04-0079  0.434
2005 Boorjian S, Scherr DS, Mongan NP, Zhuang Y, Nanus DM, Gudas LJ. Retinoid receptor mRNA expression profiles in human bladder cancer specimens. International Journal of Oncology. 26: 1041-8. PMID 15754000 DOI: 10.3892/Ijo.26.4.1041  0.393
2005 Martinez-Ceballos E, Chambon P, Gudas LJ. Differences in gene expression between wild type and Hoxa1 knockout embryonic stem cells after retinoic acid treatment or leukemia inhibitory factor (LIF) removal. The Journal of Biological Chemistry. 280: 16484-98. PMID 15722554 DOI: 10.1074/Jbc.M414397200  0.816
2005 Boorjian SA, Mongan NP, Raman JD, Nanus DM, Scherr DS, Gudas LJ. 760: Expression of TNF-Related Apoptosis Inducing Ligand (TRAIL) is Reduced in Bladder Tumor Tissue but may be Restored in Bladder Cancer Cell Lines by Treatment with Retinoic Acid Journal of Urology. 173: 206-206. DOI: 10.1016/S0022-5347(18)34929-2  0.336
2004 Boorjian S, Ugras S, Mongan NP, Gudas LJ, You X, Tickoo SK, Scherr DS. Androgen receptor expression is inversely correlated with pathologic tumor stage in bladder cancer. Urology. 64: 383-8. PMID 15302512 DOI: 10.1016/J.Urology.2004.03.025  0.332
2004 Sharif KA, Baker H, Gudas LJ. Differential regulation of laminin b1 transgene expression in the neonatal and adult mouse brain. Neuroscience. 126: 967-78. PMID 15207330 DOI: 10.1016/J.Neuroscience.2004.03.064  0.365
2004 Boorjian S, Tickoo SK, Mongan NP, Yu H, Bok D, Rando RR, Nanus DM, Scherr DS, Gudas LJ. Reduced lecithin: retinol acyltransferase expression correlates with increased pathologic tumor stage in bladder cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 3429-37. PMID 15161698 DOI: 10.1158/1078-0432.Ccr-03-0756  0.372
2004 Li R, Faria TN, Boehm M, Nabel EG, Gudas LJ. Retinoic acid causes cell growth arrest and an increase in p27 in F9 wild type but not in F9 retinoic acid receptor beta2 knockout cells. Experimental Cell Research. 294: 290-300. PMID 14980522 DOI: 10.1016/J.Yexcr.2003.11.014  0.4
2004 Tang XH, Knudsen B, Bemis D, Tickoo S, Gudas LJ. Oral cavity and esophageal carcinogenesis modeled in carcinogen-treated mice. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 301-13. PMID 14734483 DOI: 10.1158/1078-0432.Ccr-0999-3  0.308
2004 Tighe AP, Gudas LJ. Retinoic acid inhibits leukemia inhibitory factor signaling pathways in mouse embryonic stem cells. Journal of Cellular Physiology. 198: 223-9. PMID 14603524 DOI: 10.1002/Jcp.10424  0.464
2004 Fabb SA, Haines G, Dworkin S, Simmons PJ, Gudas LJ, Purton LE. Novel Roles for the Homeobox Gene, HoxA1, and Its Truncated Form, HoxA1-T, in the Regulation of Hematopoietic Stem Cell Self-Renewal. Blood. 104: 1706-1706. DOI: 10.1182/Blood.V104.11.1706.1706  0.339
2003 Costet P, Lalanne F, Gerbod-Giannone MC, Molina JR, Fu X, Lund EG, Gudas LJ, Tall AR. Retinoic acid receptor-mediated induction of ABCA1 in macrophages. Molecular and Cellular Biology. 23: 7756-66. PMID 14560020 DOI: 10.1128/Mcb.23.21.7756-7766.2003  0.321
2003 Zhuang Y, Faria TN, Chambon P, Gudas LJ. Identification and characterization of retinoic acid receptor beta2 target genes in F9 teratocarcinoma cells. Molecular Cancer Research : McR. 1: 619-30. PMID 12805409  0.353
2003 Chen AC, Yu K, Lane MA, Gudas LJ. Homozygous deletion of the CRABPI gene in AB1 embryonic stem cells results in increased CRABPII gene expression and decreased intracellular retinoic acid concentration. Archives of Biochemistry and Biophysics. 411: 159-73. PMID 12623064 DOI: 10.1016/S0003-9861(02)00732-4  0.451
2003 Mohn D, Chen SW, Dias DC, Weinstein DC, Dyer MA, Sahr K, Ducker CE, Zahradka E, Keller G, Zaret KS, Gudas LJ, Baron MH. Mouse Mix gene is activated early during differentiation of ES and F9 stem cells and induces endoderm in frog embryos. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 226: 446-59. PMID 12619131 DOI: 10.1002/Dvdy.10263  0.493
2002 Liu L, Gudas LJ. Retinoic acid induces expression of the interleukin-1beta gene in cultured normal human mammary epithelial cells and in human breast carcinoma lines. Journal of Cellular Physiology. 193: 244-52. PMID 12385002 DOI: 10.1002/Jcp.10173  0.367
2002 Thompson JR, Gudas LJ. Retinoic acid induces parietal endoderm but not primitive endoderm and visceral endoderm differentiation in F9 teratocarcinoma stem cells with a targeted deletion of the Rex-1 (Zfp-42) gene. Molecular and Cellular Endocrinology. 195: 119-33. PMID 12354678 DOI: 10.1016/S0303-7207(02)00180-6  0.464
2002 Goldberg JS, Vargas M, Rosmarin AS, Milowsky MI, Papanicoloau N, Gudas LJ, Shelton G, Feit K, Petrylak D, Nanus DM. Phase I trial of interferon alpha2b and liposome-encapsulated all-trans retinoic acid in the treatment of patients with advanced renal cell carcinoma. Cancer. 95: 1220-7. PMID 12216088 DOI: 10.1002/Cncr.10809  0.363
2002 Sahr K, Dias DC, Sanchez R, Chen D, Chen SW, Gudas LJ, Baron MH. Structure, upstream promoter region, and functional domains of a mouse and human Mix paired-like homeobox gene. Gene. 291: 135-47. PMID 12095687 DOI: 10.1016/S0378-1119(02)00590-5  0.369
2002 Huang D, Chen SW, Gudas LJ. Analysis of two distinct retinoic acid response elements in the homeobox gene Hoxb1 in transgenic mice. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 223: 353-70. PMID 11891985 DOI: 10.1002/Dvdy.10057  0.42
2002 Cerignoli F, Guo X, Cardinali B, Rinaldi C, Casaletto J, Frati L, Screpanti I, Gudas LJ, Gulino A, Thiele CJ, Giannini G. retSDR1, a short-chain retinol dehydrogenase/reductase, is retinoic acid-inducible and frequently deleted in human neuroblastoma cell lines. Cancer Research. 62: 1196-204. PMID 11861404  0.375
2001 Sharif KA, Li C, Gudas LJ. cis-acting DNA regulatory elements, including the retinoic acid response element, are required for tissue specific laminin B1 promoter/lacZ expression in transgenic mice Mechanisms of Development. 103: 13-25. PMID 11335108 DOI: 10.1016/S0925-4773(01)00326-4  0.358
2001 Guo X, Morris PL, Gudas LJ. Follicle-stimulating hormone and leukemia inhibitory factor regulate Sertoli cell retinol metabolism Endocrinology. 142: 1024-1032. PMID 11181515 DOI: 10.1210/Endo.142.3.7996  0.336
2000 Guo X, Ruiz A, Rando RR, Bok D, Gudas LJ. Esterification of all-trans-retinol in normal human epithelial cell strains and carcinoma lines from oral cavity, skin and breast: reduced expression of lecithin:retinol acyltransferase in carcinoma lines. Carcinogenesis. 21: 1925-33. PMID 11062150 DOI: 10.1093/Carcin/21.11.1925  0.389
2000 Choi I, Gudas LJ, Katzenellenbogen BS. Regulation of keratin 19 gene expression by estrogen in human breast cancer cells and identification of the estrogen responsive gene region Molecular and Cellular Endocrinology. 164: 225-237. PMID 11026574 DOI: 10.1016/S0303-7207(00)00197-0  0.347
2000 Shen J, Wu H, Gudas LJ. Molecular cloning and analysis of a group of genes differentially expressed in cells which overexpress the Hoxa-1 homeobox gene Experimental Cell Research. 259: 274-283. PMID 10942599 DOI: 10.1006/Excr.2000.4963  0.475
2000 Means AL, Thompson JR, Gudas LJ. Transcriptional regulation of the cellular retinoic acid binding protein I gene in F9 teratocarcinoma cells Cell Growth and Differentiation. 11: 71-82. PMID 10714763  0.364
2000 Shen J, Gudas LJ. Molecular cloning of a novel retinoic acid-responsive gene, HA1R-62, which is also up-regulated in Hoxa-1-overexpressing cells Cell Growth and Differentiation. 11: 11-17. PMID 10672899  0.34
1999 Lane MA, Chen AC, Roman SD, Derguini F, Gudas LJ. Removal of LIF (leukemia inhibitory factor) results in increased vitamin A (retinol) metabolism to 4-oxoretinol in embryonic stem cells. Proceedings of the National Academy of Sciences of the United States of America. 96: 13524-9. PMID 10557354 DOI: 10.1073/Pnas.96.23.13524  0.447
1999 Faria TN, Mendelsohn C, Chambon P, Gudas LJ. The targeted disruption of both alleles of RARβ2 in F9 cells results in the loss of retinoic acid-associated growth arrest Journal of Biological Chemistry. 274: 26783-26788. PMID 10480883 DOI: 10.1074/Jbc.274.38.26783  0.454
1998 Thompson JR, Huang DY, Gudas LJ. The murine Hoxb1 3' RAIDR5 enhancer contains multiple regulatory elements. Cell Growth & Differentiation : the Molecular Biology Journal of the American Association For Cancer Research. 9: 969-81. PMID 9869297  0.31
1998 Faria TN, LaRosa GJ, Wilen E, Liao J, Gudas LJ. Characterization of genes which exhibit reduced expression during the retinoic acid-induced differentiation of F9 teratocarcinoma cells: Involvement of cyclin D3 in RA-mediated growth arrest Molecular and Cellular Endocrinology. 143: 155-166. PMID 9806360 DOI: 10.1016/S0303-7207(98)00127-0  0.439
1998 Huang D, Chen SW, Langston AW, Gudas LJ. A conserved retinoic acid responsive element in the murine Hoxb-1 gene is required for expression in the developing gut Development. 125: 3235-3246. PMID 9671595  0.315
1998 Faria TN, Rivi R, Derguini F, Pandolfi PP, Gudas LJ. 4-Oxoretinol, a metabolite of retinol in the human promyelocytic leukemia cell line NB4, induces cell growth arrest and granulocytic differentiation. Cancer Research. 58: 2007-13. PMID 9581846  0.355
1998 Ben-Shushan E, Thompson JR, Gudas LJ, Bergman Y. Rex-1, a gene encoding a transcription factor expressed in the early embryo, is regulated via Oct-3/4 and Oct-6 binding to an octamer site and a novel protein, Rox-1, binding to an adjacent site Molecular and Cellular Biology. 18: 1866-1878. PMID 9528758 DOI: 10.1128/Mcb.18.4.1866  0.436
1998 Thompson JR, Chen SW, Ho L, Langston AW, Gudas LJ. An evolutionary conserved element is essential for somite and adjacent mesenchymal expression of the Hoxa1 gene Developmental Dynamics. 211: 97-108. PMID 9438427 DOI: 10.1002/(Sici)1097-0177(199801)211:1<97::Aid-Aja9>3.0.Co;2-2  0.415
1997 Li C, Gudas LJ. Sequences 5' of the basement membrane laminin β1 chain gene (LAMB1) direct the expression of β-galactosidase during development of the mouse testis and ovary Differentiation. 62: 129-137. PMID 9447707 DOI: 10.1046/J.1432-0436.1997.6230129.X  0.362
1997 Shen J, Li C, Gudas LJ. Regulation of the laminin β1 (LAMB1), retinoic acid receptor β, and bone morphogenetic protein 2 genes in mutant F9 teratocarcinoma cell lines partially deficient in cyclic AMP-dependent protein kinase activity Cell Growth and Differentiation. 8: 1297-1304. PMID 9419418  0.33
1997 Means AL, Gudas LJ. The CRABP I gene contains two separable, redundant regulatory regions active in neural tissues in transgenic mouse embryos Developmental Dynamics. 209: 59-69. PMID 9142496 DOI: 10.1002/(Sici)1097-0177(199705)209:1<59::Aid-Aja6>3.0.Co;2-W  0.351
1997 Langston AW, Thompson JR, Gudas LJ. Retinoic acid-responsive enhancers located 3' of the Hox A and Hox B homeobox gene clusters. Functional analysis Journal of Biological Chemistry. 272: 2167-2175. PMID 8999919 DOI: 10.1074/Jbc.272.4.2167  0.407
1996 Chen AC, Gudas LJ. An analysis of retinoic acid-induced gene expression and metabolism in AB1 embryonic stem cells Journal of Biological Chemistry. 271: 14971-14980. PMID 8663043 DOI: 10.1074/Jbc.271.25.14971  0.408
1996 Achkar CC, Derguini F, Blumberg B, Langston A, Levin AA, Speck J, Evans RM, Bolado J, Nakanishi K, Buck J, Gudas LJ. 4-Oxoretinol, a new natural ligand and transactivator of the retinoic acid receptors. Proceedings of the National Academy of Sciences of the United States of America. 93: 4879-84. PMID 8643497 DOI: 10.1073/Pnas.93.10.4879  0.444
1996 Li C, Gudas LJ. Murine laminin B1 gene regulation during the retinoic acid- and dibutyryl cyclic AMP-induced differentiation of embryonic F9 teratocarcinoma stem cells Journal of Biological Chemistry. 271: 6810-6818. PMID 8636104 DOI: 10.1074/Jbc.271.12.6810  0.445
1995 Boylan JF, Lufkin T, Achkar CC, Taneja R, Chambon P, Gudas LJ. Targeted disruption of retinoic acid receptor α (RARα and RARγ results in receptor-specific alterations in retinoic acid-mediated differentiation and retinoic acid metabolism Molecular and Cellular Biology. 15: 843-851. PMID 7823950 DOI: 10.1128/Mcb.15.2.843  0.484
1995 Taneja R, Bouillet P, Boylan JF, Gaub MP, Roy B, Gudas LJ, Chambon P. Reexpression of retinoic acid receptor (RAR)γ or overexpression of RARα or RARβ in RARγ-null F9 cells reveals a partial functional redundancy between the three RAR types Proceedings of the National Academy of Sciences of the United States of America. 92: 7854-7858. PMID 7644503 DOI: 10.1073/Pnas.92.17.7854  0.494
1995 Means AL, Gudas LJ. The roles of retinoids in vertebrate development Annual Review of Biochemistry. 64: 201-233. PMID 7574480 DOI: 10.1146/Annurev.Bi.64.070195.001221  0.35
1994 Anderson R, Landry M, Reginelli A, Taylor G, Achkar C, Gudas L, Muneoka K. Conversion of anterior limb bud cells to ZPA signaling cells in vitro and in vivo. Developmental Biology. 164: 241-57. PMID 8026627 DOI: 10.1006/Dbio.1994.1195  0.365
1994 Langston AW, Gudas LJ. Retinoic acid and homeobox gene regulation Current Opinion in Genetics and Development. 4: 550-555. PMID 7950323 DOI: 10.1016/0959-437X(94)90071-A  0.374
1994 Ho L, Mercola M, Gudas LJ. Xenopus laevis cellular retinoic acid-binding protein: temporal and spatial expression pattern during early embryogenesis. Mechanisms of Development. 47: 53-64. PMID 7947321 DOI: 10.1016/0925-4773(94)90095-7  0.409
1994 Ho L, Symes K, Yordán C, Gudas LJ, Mercola M. Localization of PDGF A and PDGFR alpha mRNA in Xenopus embryos suggests signalling from neural ectoderm and pharyngeal endoderm to neural crest cells. Mechanisms of Development. 48: 165-74. PMID 7893600 DOI: 10.1016/0925-4773(94)90057-4  0.303
1994 Love JM, Gudas LJ. Vitamin A, differentiation and cancer Current Opinion in Cell Biology. 6: 825-831. PMID 7880529 DOI: 10.1016/0955-0674(94)90051-5  0.461
1993 Hosler BA, Rogers MB, Kozak CA, Gudas LJ. An octamer motif contributes to the expression of the retinoic acid-regulated zinc finger gene Rex-1 (Zfp-42) in F9 teratocarcinoma cells. Molecular and Cellular Biology. 13: 2919-28. PMID 8474450 DOI: 10.1128/Mcb.13.5.2919  0.469
1993 McCaffrery P, Posch KC, Napoli JL, Gudas L, Dräger UC. Changing patterns of the retinoic acid system in the developing retina. Developmental Biology. 158: 390-9. PMID 8393814 DOI: 10.1006/Dbio.1993.1197  0.327
1993 Boylan JF, Lohnes D, Taneja R, Chambon P, Gudas LJ. Loss of retinoic acid receptor γ function in F9 cells by gene disruption results in aberrant Hoxa-1 expression and differentiation upon retinoic acid treatment Proceedings of the National Academy of Sciences of the United States of America. 90: 9601-9605. PMID 8105479 DOI: 10.1073/Pnas.90.20.9601  0.456
1993 Pratt MAC, Langston AW, Gudas LJ, McBurney MW. Retinoic acid fails to induce expression of Hox genes in differentiation-defective murine embryonal carcinoma cells carrying a mutant gene for alpha retinoic acid receptor Differentiation. 53: 105-113. PMID 8103017 DOI: 10.1111/J.1432-0436.1993.Tb00650.X  0.502
1992 Rogers MB, Rosen V, Wozney JM, Gudas LJ. Bone morphogenetic proteins-2 and -4 are involved in the retinoic acid-induced differentiation of embryonal carcinoma cells. Molecular Biology of the Cell. 3: 189-96. PMID 1550961 DOI: 10.1091/Mbc.3.2.189  0.409
1992 Braunhut SJ, D'Amore PA, Gudas LJ. The location and expression of fibroblast growth factor (FGF) in F9 visceral and parietal embryonic cells after retinoic acid-induced differentiation Differentiation. 50: 141-152. PMID 1426701 DOI: 10.1111/J.1432-0436.1992.Tb00669.X  0.428
1992 Langston AW, Gudas LJ. Identification of a retinoic acid responsive enhancer 3′ of the murine homeobox gene Hox-1.6 Mechanisms of Development. 38: 217-227. PMID 1360810 DOI: 10.1016/0925-4773(92)90055-O  0.411
1992 Gudas LJ. Retinoids, retinoid-responsive genes, cell differentiation, and cancer Cell Growth &Amp; Differentiation : the Molecular Biology Journal of the American Association For Cancer Research. 3: 655-662. PMID 1358181  0.31
1992 Goliger JA, Gudas LJ. Mouse F9 teratocarcinoma stem cells expressing the stably transfected homeobox gene Hox 1.6 exhibit an altered morphology Gene Expression. 2: 147-160. PMID 1353003  0.398
1992 Boylan JF, Gudas LJ. The level of CRABP-I expression influences the amounts and types of all- trans-retinoic acid metabolites in F9 teratocarcinoma stem cells Journal of Biological Chemistry. 267: 21486-21491. PMID 1328234  0.343
1992 Weiler-Guettler H, Yu K, Soff G, Gudas LJ, Rosenberg RD. Thrombomodulin gene regulation by cAMP and retinoic acid in F9 embryonal carcinoma cells. Proceedings of the National Academy of Sciences of the United States of America. 89: 2155-9. PMID 1312715 DOI: 10.1073/Pnas.89.6.2155  0.448
1991 Boylan JF, Gudas LJ. Overexpression of the cellular retinoic acid binding protein-I (CRABP-I) results in a reduction in differentiation-specific gene expression in F9 teratocarcinoma cells Journal of Cell Biology. 112: 965-979. PMID 1847931 DOI: 10.1083/Jcb.112.5.965  0.475
1991 Rogers MB, Hosler BA, Gudas LJ. Specific expression of a retinoic acid-regulated, zinc-finger gene, Rex-1, in preimplantation embryos, trophoblast and spermatocytes. Development (Cambridge, England). 113: 815-24. PMID 1821852  0.398
1991 Crowel DL, Hu L, Gudas LJ, Rheinwald JG. Variable expression of retinoic acid receptor (RARβ) mRNA in human oral and epidermal keratinocytes; Relation to keratin 19 expression and keratinization potential Differentiation. 48: 199-208. PMID 1725165 DOI: 10.1111/J.1432-0436.1991.Tb00258.X  0.375
1991 Hu L, Crowe DL, Rheinwald JG, Chambon P, Gudas LJ. Abnormal Expression of Retinoic Acid Receptors and Keratin 19 by Human Oral and Epidermal Squamous Cell Carcinoma Cell Lines Cancer Research. 51: 3972-3981. PMID 1713123  0.32
1991 Sasaki AW, Doskow J, MacLeod CL, Rogers MB, Gudas LJ, Wilkinson MF. The oncofetal gene Pem encodes a homeodomain and is regulated in primordial and pre-muscle stem cells. Mechanisms of Development. 34: 155-64. PMID 1680379 DOI: 10.1016/0925-4773(91)90052-8  0.479
1991 Vasios G, Mader S, Gold JD, Leid M, Lutz Y, Gaub MP, Chambon P, Gudas L. The late retinoic acid induction of laminin B1 gene transcription involves RAR binding to the responsive element. The Embo Journal. 10: 1149-1158. DOI: 10.1002/J.1460-2075.1991.Tb08055.X  0.428
1990 Gudas LJ, Grippo JF, Kim KW, Larosa GJ, Stoner CM. The regulation of the expression of genes encoding basement membrane proteins during the retinoic acid-associated differentiation of murine teratocarcinoma cells Annals of the New York Academy of Sciences. 580: 245-251. PMID 2337299 DOI: 10.1111/J.1749-6632.1990.Tb17933.X  0.417
1990 Hu L, Gudas LJ. Cyclic AMP analogs and retinoic acid influence the expression of retinoic acid receptor α, β, and γ mRNAs in F9 teratocarcinoma cells Molecular and Cellular Biology. 10: 391-396. PMID 2152965 DOI: 10.1128/Mcb.10.1.391  0.377
1990 Gudas LJ. Assays for expression of genes regulated by retinoic acid in murine teratocarcinoma cell lines Methods in Enzymology. 190: 131-140. PMID 1965001 DOI: 10.1016/0076-6879(90)90017-U  0.419
1990 Rogers MB, Watkins SC, Gudas LJ. Gene expression in visceral endoderm: a comparison of mutant and wild-type F9 embryonal carcinoma cell differentiation. The Journal of Cell Biology. 110: 1767-77. PMID 1692330 DOI: 10.1083/Jcb.110.5.1767  0.421
1989 Vasios GW, Gold JD, Petkovich M, Chambon P, Gudas LJ. A retinoic acid-responsive element is present in the 5' flanking region of the laminin B1 gene Proceedings of the National Academy of Sciences of the United States of America. 86: 9099-9103. PMID 2556699 DOI: 10.1073/Pnas.86.23.9099  0.46
1989 Wang SY, Roguska MA, Gudas LJ. Defective post-translational modification of collagen IV in a mutant F9 teratocarcinoma cell line is associated with delayed differentiation and growth arrest in response to retinoic acid Journal of Biological Chemistry. 264: 15556-15564. PMID 2549067  0.334
1989 Braunhut SJ, Gudas LJ, Kurokawa T, Sasse J, D'Amore PA. Expression of fibroblast growth factor by F9 teratocarcinoma cells as a function of differentiation Journal of Cell Biology. 108: 2467-2476. PMID 2544608 DOI: 10.1083/Jcb.108.6.2467  0.434
1989 Stoner CM, Gudas LJ. Mouse Cellular Retinoic Acid Binding Protein: Cloning, Complementary DNA Sequence, and Messenger RNA Expression during the Retinoic Acid-induced Differentiation of F9 Wild Type and RA-3-10 Mutant Teratocarcinoma Cells Cancer Research. 49: 1497-1504. PMID 2538228  0.343
1989 Hosler BA, LaRosa GJ, Grippo JF, Gudas LJ. Expression of REX-1, a gene containing zinc finger motifs, is rapidly reduced by retinoic acid in F9 teratocarcinoma cells Molecular and Cellular Biology. 9: 5623-5629. PMID 2511439 DOI: 10.1128/Mcb.9.12.5623  0.467
1988 LaRosa GJ, Gudas LJ. An early effect of retinoic acid: cloning of an mRNA (Era-1) exhibiting rapid and protein synthesis-independent induction during teratocarcinoma stem cell differentiation Proceedings of the National Academy of Sciences of the United States of America. 85: 329-333. PMID 3422432 DOI: 10.1073/Pnas.85.2.329  0.46
1988 LaRosa GJ, Gudas LJ. Early retinoic acid-induced F9 teratocarcinoma stem cell gene ERA-1: Alternate splicing creates transcripts for a homeobox-containing protein and one lacking the homeobox Molecular and Cellular Biology. 8: 3906-3917. PMID 2906112 DOI: 10.1128/Mcb.8.9.3906  0.474
1988 Wang SY, Gudas LJ. Protein synthesis inhibitors prevent the induction of laminin B1, collagen IV (α1), and other differentiation-specific mRNAs by retinoic acid in F9 teratocarcinoma cells Journal of Cellular Physiology. 136: 305-311. PMID 2842348 DOI: 10.1002/Jcp.1041360213  0.437
1987 Albert DA, Gudas LJ, Nodzenski E. Deoxyribonucleotide metabolism and cyclic AMP resistance in hydroxyurea-resistant S49 T-lymphoma cells Journal of Cellular Physiology. 130: 262-269. PMID 3029148 DOI: 10.1002/Jcp.1041300212  0.349
1986 Albert DA, Gudas LJ. Selection and characterization of mutant S49 T-lymphoma cell lines resistant to phosphonoformic acid: Evidence for inhibition of ribonucleotide reductase Journal of Cellular Physiology. 127: 281-287. PMID 2939095 DOI: 10.1002/Jcp.1041270214  0.352
1985 Roguska MA, Gudas LJ. An increase in prolyl-4-hydroxylase activity occurs during the retinoic acid-induced differentiation of mouse teratocarcinoma stem cell lines F9 and P19 Journal of Biological Chemistry. 260: 13893-13896. PMID 2997185  0.334
1985 Wang SY, LaRosa GJ, Gudas LJ. Molecular cloning of gene sequences transcriptionally regulated by retinoic acid and dibutyryl cyclic AMP in cultured mouse teratocarcinoma cells Developmental Biology. 107: 75-86. PMID 2981185 DOI: 10.1016/0012-1606(85)90377-X  0.475
1985 Gudas LJ, Roguska M, Wang SY. Defective prolyl-4-hydroxylase activity associated with defective differentiation in response to retinoic acid in a mutant F9 mouse teratocarcinoma stem cell line Annals of the New York Academy of Sciences. 445-448. DOI: 10.1111/J.1749-6632.1985.Tb51205.X  0.359
1984 Levine RA, LaRosa GJ, Gudas LJ. Isolation of cDNA clones for genes exhibiting reduced expression after differentiation of murine teratocarcinoma stem cells Molecular and Cellular Biology. 4: -2150. PMID 6095043 DOI: 10.1128/Mcb.4.10.2142  0.473
1984 Levine RA, Campisi J, Wang SY, Gudas LJ. Butyrate inhibits the retinoic acid-induced differentiation of F9 teratocarcinoma stem cells Developmental Biology. 105: 443-450. PMID 6090244 DOI: 10.1016/0012-1606(84)90301-4  0.432
1983 Wang SY, Gudas LJ. Isolation of cDNA clones specific for collagen IV and laminin from mouse teratocarcinoma cells Proceedings of the National Academy of Sciences of the United States of America. 80: 5880-5884. PMID 6310600 DOI: 10.1073/Pnas.80.19.5880  0.342
1980 Ullman B, Wormsted MA, Levinson BB, Gudas LJ, Cohen A, Clift SM, Martin DW. Abnormal regulation of purine metabolism in a cultured mouse T-cell lymphoma mutant partially deficient in adenylosuccinate synthetase. Advances in Experimental Medicine and Biology. 375-86. PMID 6158849 DOI: 10.1007/978-1-4615-9140-5_61  0.38
1979 Ullman B, Clift SM, Cohen A, Gudas LJ, Levinson BB, Wormsted MA, Martin DW. Abnormal regulation of de novo purine synthesis and purine salvage in a cultured mouse T-cell lymphoma mutant partially deficient in adenylosuccinate synthetase. Journal of Cellular Physiology. 99: 139-51. PMID 222775 DOI: 10.1002/Jcp.1040990115  0.381
1979 Ullman B, Gudas LJ, Clift SM, Martin DW. Isolation and characterization of purine-nucleoside phosphorylase-deficient T-lymphoma cells and secondary mutants with altered ribonucleotide reductase: Genetic model for immunodeficiency disease Proceedings of the National Academy of Sciences of the United States of America. 76: 1074-1078. PMID 108675 DOI: 10.1073/Pnas.76.3.1074  0.323
1978 Gudas LJ, Cohen A, Ullman B, Martin DW. Analysis of adenosine-mediated pyrimidine starvation using cultured wild-type and mutant mouse T-lymphoma cells Somatic Cell Genetics. 4: 201-219. PMID 307279 DOI: 10.1007/Bf01538985  0.311
1978 Ullman B, Gudas LJ, Cohen A, Martin DW. Deoxyadenosine metabolism and cytotoxicity in cultured mouse T lymphoma cells: a model for immunodeficiency disease Cell. 14: 365-375. PMID 208780 DOI: 10.1016/0092-8674(78)90122-8  0.373
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