Rajiv Ratan - Publications

Affiliations: 
Neurology Weill Cornell Medical College, New York, NY, United States 
Area:
neurodegeneration

140 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Alim I, Caulfield JT, Chen Y, Swarup V, Geschwind DH, Ivanova E, Seravalli J, Ai Y, Sansing LH, Ste Marie EJ, Hondal RJ, Mukherjee S, Cave JW, Sagdullaev BT, Karuppagounder SS, ... Ratan RR, et al. Selenium Drives a Transcriptional Adaptive Program to Block Ferroptosis and Treat Stroke. Cell. PMID 31056284 DOI: 10.1016/j.cell.2019.03.032  0.4
2016 Karuppagounder SS, Alim I, Khim SJ, Bourassa MW, Sleiman SF, John R, Thinnes CC, Yeh TL, Demetriades M, Neitemeier S, Cruz D, Gazaryan I, Killilea DW, Morgenstern L, Xi G, ... ... Ratan RR, et al. Therapeutic targeting of oxygen-sensing prolyl hydroxylases abrogates ATF4-dependent neuronal death and improves outcomes after brain hemorrhage in several rodent models. Science Translational Medicine. 8: 328ra29. PMID 26936506 DOI: 10.1126/scitranslmed.aac6008  0.56
2016 Bourassa MW, Alim I, Bultman SJ, Ratan RR. Butyrate, Neuroepigenetics and the Gut Microbiome: Can a High Fiber Diet Improve Brain Health? Neuroscience Letters. PMID 26868600 DOI: 10.1016/j.neulet.2016.02.009  0.56
2015 Karuppagounder SS, Kumar A, Shao DS, Zille M, Bourassa MW, Caulfield JT, Alim I, Ratan RR. Metabolism and epigenetics in the nervous system: Creating cellular fitness and resistance to neuronal death in neurological conditions via modulation of oxygen-, iron-, and 2-oxoglutarate-dependent dioxygenases. Brain Research. PMID 26232572 DOI: 10.1016/j.brainres.2015.07.030  0.4
2015 Olson DE, Sleiman SF, Bourassa MW, Wagner FF, Gale JP, Zhang YL, Ratan RR, Holson EB. Hydroxamate-based histone deacetylase inhibitors can protect neurons from oxidative stress via a histone deacetylase-independent catalase-like mechanism. Chemistry & Biology. 22: 439-45. PMID 25892200 DOI: 10.1016/j.chembiol.2015.03.014  0.56
2015 Aleyasin H, Karuppagounder SS, Kumar A, Sleiman S, Basso M, Ma T, Siddiq A, Chinta SJ, Brochier C, Langley B, Haskew-Layton R, Bane SL, Riggins GJ, Gazaryan I, Starkov AA, ... ... Ratan RR, et al. Antihelminthic benzimidazoles are novel HIF activators that prevent oxidative neuronal death via binding to tubulin. Antioxidants & Redox Signaling. 22: 121-34. PMID 24766300 DOI: 10.1089/ars.2013.5595  0.56
2015 Sleiman SF, Olson DE, Bourassa MW, Karuppagounder SS, Zhang YL, Gale J, Wagner FF, Basso M, Coppola G, Pinto JT, Holson EB, Ratan RR. Correction: Sleiman et al., hydroxamic acid-based histone deacetylase (HDAC) inhibitors can mediate neuroprotection independent of hdac inhibition Journal of Neuroscience. 35: 438. DOI: 10.1523/JNEUROSCI.4746-14.2015  0.56
2015 Karuppagounder SS, Kumar A, Shao DS, Zille M, Bourassa MW, Caulfield JT, Alim I, Ratan RR. Metabolism and epigenetics in the nervous system: Creating cellular fitness and resistance to neuronal death in neurological conditions via modulation of oxygen-, iron-, and 2-oxoglutarate-dependent dioxygenases Brain Research. DOI: 10.1016/j.brainres.2015.07.030  0.56
2014 Alim I, Haskew-Layton RE, Aleyasin H, Guo H, Ratan RR. Spatial, temporal, and quantitative manipulation of intracellular hydrogen peroxide in cultured cells. Methods in Enzymology. 547: 251-73. PMID 25416362 DOI: 10.1016/B978-0-12-801415-8.00014-X  0.56
2014 Guo H, Aleyasin H, Dickinson BC, Haskew-Layton RE, Ratan RR. Recent advances in hydrogen peroxide imaging for biological applications. Cell & Bioscience. 4: 64. PMID 25400906 DOI: 10.1186/2045-3701-4-64  0.56
2014 Sleiman SF, Olson DE, Bourassa MW, Karuppagounder SS, Zhang YL, Gale J, Wagner FF, Basso M, Coppola G, Pinto JT, Holson EB, Ratan RR. Hydroxamic acid-based histone deacetylase (HDAC) inhibitors can mediate neuroprotection independent of HDAC inhibition. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 14328-37. PMID 25339746 DOI: 10.1523/JNEUROSCI.1010-14.2014  0.56
2014 Ma TC, Barco A, Ratan RR, Willis DE. cAMP-responsive element-binding protein (CREB) and cAMP co-regulate activator protein 1 (AP1)-dependent regeneration-associated gene expression and neurite growth. The Journal of Biological Chemistry. 289: 32914-25. PMID 25296755 DOI: 10.1074/jbc.M114.582460  0.56
2014 Prusevich P, Kalin JH, Ming SA, Basso M, Givens J, Li X, Hu J, Taylor MS, Cieniewicz AM, Hsiao PY, Huang R, Roberson H, Adejola N, Avery LB, Casero RA, ... ... Ratan RR, et al. A selective phenelzine analogue inhibitor of histone demethylase LSD1. Acs Chemical Biology. 9: 1284-93. PMID 24707965 DOI: 10.1021/cb500018s  0.56
2014 Bourassa MW, Ratan RR. The interplay between microRNAs and histone deacetylases in neurological diseases. Neurochemistry International. 77: 33-9. PMID 24681158 DOI: 10.1016/j.neuint.2014.03.012  0.56
2014 Kumar A, Vaish M, Ratan RR. Transcriptional dysregulation in Huntington's disease: a failure of adaptive transcriptional homeostasis. Drug Discovery Today. 19: 956-62. PMID 24662036 DOI: 10.1016/j.drudis.2014.03.016  0.56
2014 Qin L, Jing D, Parauda S, Carmel J, Ratan RR, Lee FS, Cho S. An adaptive role for BDNF Val66Met polymorphism in motor recovery in chronic stroke. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 2493-502. PMID 24523540 DOI: 10.1523/JNEUROSCI.4140-13.2014  0.56
2013 Brand D, Ratan RR. Epigenetics and the environment: in search of the "toleroasome" vital to execution of ischemic preconditioning. Translational Stroke Research. 4: 56-62. PMID 24323190 DOI: 10.1007/s12975-012-0235-0  0.56
2013 Basso M, Sleiman S, Ratan RR. Looking above but not beyond the genome for therapeutics in neurology and psychiatry: epigenetic proteins and RNAs find a new focus. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 10: 551-5. PMID 24092616 DOI: 10.1007/s13311-013-0225-2  0.56
2013 Elder J, Cortes M, Rykman A, Hill J, Karuppagounder S, Edwards D, Ratan RR. The epigenetics of stroke recovery and rehabilitation: from polycomb to histone deacetylases. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 10: 808-16. PMID 24092615 DOI: 10.1007/s13311-013-0224-3  0.56
2013 Guo H, Aleyasin H, Howard SS, Dickinson BC, Lin VS, Haskew-Layton RE, Xu C, Chen Y, Ratan RR. Two-photon fluorescence imaging of intracellular hydrogen peroxide with chemoselective fluorescent probes. Journal of Biomedical Optics. 18: 106002. PMID 24084856 DOI: 10.1117/1.JBO.18.10.106002  0.56
2013 Brochier C, Dennis G, Rivieccio MA, McLaughlin K, Coppola G, Ratan RR, Langley B. Specific acetylation of p53 by HDAC inhibition prevents DNA damage-induced apoptosis in neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 8621-32. PMID 23678107 DOI: 10.1523/JNEUROSCI.5214-12.2013  0.56
2013 Basso M, Ratan RR. Transglutaminase is a therapeutic target for oxidative stress, excitotoxicity and stroke: a new epigenetic kid on the CNS block. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 33: 809-18. PMID 23571278 DOI: 10.1038/jcbfm.2013.53  0.56
2013 Ferguson AR, Irvine KA, Gensel JC, Nielson JL, Lin A, Ly J, Segal MR, Ratan RR, Bresnahan JC, Beattie MS. Derivation of multivariate syndromic outcome metrics for consistent testing across multiple models of cervical spinal cord injury in rats. Plos One. 8: e59712. PMID 23544088 DOI: 10.1371/journal.pone.0059712  0.56
2013 Karuppagounder SS, Basso M, Sleiman SF, Ma TC, Speer RE, Smirnova NA, Gazaryan IG, Ratan RR. In vitro ischemia suppresses hypoxic induction of hypoxia-inducible factor-1α by inhibition of synthesis and not enhanced degradation. Journal of Neuroscience Research. 91: 1066-75. PMID 23456821 DOI: 10.1002/jnr.23204  0.56
2013 Lee J, Hwang YJ, Shin JY, Lee WC, Wie J, Kim KY, Lee MY, Hwang D, Ratan RR, Pae AN, Kowall NW, So I, Kim JI, Ryu H. Epigenetic regulation of cholinergic receptor M1 (CHRM1) by histone H3K9me3 impairs Ca(2+) signaling in Huntington's disease. Acta Neuropathologica. 125: 727-39. PMID 23455440 DOI: 10.1007/s00401-013-1103-z  0.56
2013 Speer RE, Karuppagounder SS, Basso M, Sleiman SF, Kumar A, Brand D, Smirnova N, Gazaryan I, Khim SJ, Ratan RR. Hypoxia-inducible factor prolyl hydroxylases as targets for neuroprotection by "antioxidant" metal chelators: From ferroptosis to stroke. Free Radical Biology & Medicine. 62: 26-36. PMID 23376032 DOI: 10.1016/j.freeradbiomed.2013.01.026  0.56
2013 Haskew-Layton RE, Payappilly JB, Xu H, Bennett SA, Ratan RR. 15-Deoxy-Δ12,14-prostaglandin J2 (15d-PGJ2) protects neurons from oxidative death via an Nrf2 astrocyte-specific mechanism independent of PPARγ. Journal of Neurochemistry. 124: 536-47. PMID 23199167 DOI: 10.1111/jnc.12107  0.56
2013 Yigitkanli K, Pekcec A, Karatas H, Pallast S, Mandeville E, Joshi N, Smirnova N, Gazaryan I, Ratan RR, Witztum JL, Montaner J, Holman TR, Lo EH, van Leyen K. Inhibition of 12/15-lipoxygenase as therapeutic strategy to treat stroke. Annals of Neurology. 73: 129-35. PMID 23192915 DOI: 10.1002/ana.23734  0.56
2013 Ma TC, Langley B, Ko B, Wei N, Gazaryan IG, Zareen N, Yamashiro DJ, Willis DE, Ratan RR. A screen for inducers of p21(waf1/cip1) identifies HIF prolyl hydroxylase inhibitors as neuroprotective agents with antitumor properties. Neurobiology of Disease. 49: 13-21. PMID 22944173 DOI: 10.1016/j.nbd.2012.08.016  0.56
2013 Kaidery NA, Banerjee R, Yang L, Smirnova NA, Hushpulian DM, Liby KT, Williams CR, Yamamoto M, Kensler TW, Ratan RR, Sporn MB, Beal MF, Gazaryan IG, Thomas B. Targeting Nrf2-mediated gene transcription by extremely potent synthetic triterpenoids attenuate dopaminergic neurotoxicity in the MPTP mouse model of Parkinson's disease. Antioxidants & Redox Signaling. 18: 139-57. PMID 22746536 DOI: 10.1089/ars.2011.4491  0.56
2013 Chen Y, Guo H, Gong W, Qin L, Aleyasin H, Ratan RR, Cho S, Chen J, Xie S. Recent advances in two-photon imaging: Technology developments and biomedical applications Chinese Optics Letters. 11. DOI: 10.3788/COL201311.011703  0.56
2012 Smirnova NA, Hushpulian DM, Speer RE, Gaisina IN, Ratan RR, Gazaryan IG. Catalytic mechanism and substrate specificity of HIF prolyl hydroxylases. Biochemistry. BiokhimiiÍ¡A. 77: 1108-19. PMID 23157291 DOI: 10.1134/S0006297912100033  0.56
2012 Mahishi LH, Hart RP, Lynch DR, Ratan RR. miR-886-3p levels are elevated in Friedreich ataxia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 9369-73. PMID 22764244 DOI: 10.1523/JNEUROSCI.0059-12.2012  0.56
2012 Chen Y, Wang JJ, Li J, Hosoya KI, Ratan R, Townes T, Zhang SX. Activating transcription factor 4 mediates hyperglycaemia-induced endothelial inflammation and retinal vascular leakage through activation of STAT3 in a mouse model of type 1 diabetes. Diabetologia. 55: 2533-45. PMID 22660795 DOI: 10.1007/s00125-012-2594-1  0.56
2012 Basso M, Berlin J, Xia L, Sleiman SF, Ko B, Haskew-Layton R, Kim E, Antonyak MA, Cerione RA, Iismaa SE, Willis D, Cho S, Ratan RR. Transglutaminase inhibition protects against oxidative stress-induced neuronal death downstream of pathological ERK activation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 6561-9. PMID 22573678 DOI: 10.1523/JNEUROSCI.3353-11.2012  0.56
2012 Martin RJ, Ratan RR, Reding MJ, Olsen TS. Higher Blood Glucose within the Normal Range Is Associated with More Severe Strokes. Stroke Research and Treatment. 2012: 659610. PMID 22550616 DOI: 10.1155/2012/659610  0.56
2012 Vuppalanchi D, Merianda TT, Donnelly C, Pacheco A, Williams G, Yoo S, Ratan RR, Willis DE, Twiss JL. Lysophosphatidic acid differentially regulates axonal mRNA translation through 5'UTR elements. Molecular and Cellular Neurosciences. 50: 136-46. PMID 22522146 DOI: 10.1016/j.mcn.2012.04.001  0.56
2012 Bao Y, Qin L, Kim E, Bhosle S, Guo H, Febbraio M, Haskew-Layton RE, Ratan R, Cho S. CD36 is involved in astrocyte activation and astroglial scar formation. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 32: 1567-77. PMID 22510603 DOI: 10.1038/jcbfm.2012.52  0.56
2012 Karuppagounder SS, Ratan RR. Hypoxia-inducible factor prolyl hydroxylase inhibition: robust new target or another big bust for stroke therapeutics? Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 32: 1347-61. PMID 22415525 DOI: 10.1038/jcbfm.2012.28  0.56
2012 Zhong Y, Li J, Chen Y, Wang JJ, Ratan R, Zhang SX. Activation of endoplasmic reticulum stress by hyperglycemia is essential for Müller cell-derived inflammatory cytokine production in diabetes. Diabetes. 61: 492-504. PMID 22228718 DOI: 10.2337/db11-0315  0.56
2011 Sleiman SF, Berlin J, Basso M, Karuppagounder SS, Rohr J, Ratan RR. Histone Deacetylase Inhibitors and Mithramycin A Impact a Similar Neuroprotective Pathway at a Crossroad between Cancer and Neurodegeneration. Pharmaceuticals (Basel, Switzerland). 4: 1183-1195. PMID 22582024 DOI: 10.3390/ph4081183  0.56
2011 Ratan RR, Goldfine AM. Improving precision in therapeutics for brain recovery: throwing out the bath water and not the baby. Current Opinion in Neurology. 24: 556-7. PMID 21986683 DOI: 10.1097/WCO.0b013e32834cfc77  0.56
2011 Smirnova NA, Haskew-Layton RE, Basso M, Hushpulian DM, Payappilly JB, Speer RE, Ahn YH, Rakhman I, Cole PA, Pinto JT, Ratan RR, Gazaryan IG. Development of Neh2-luciferase reporter and its application for high throughput screening and real-time monitoring of Nrf2 activators. Chemistry & Biology. 18: 752-65. PMID 21700211 DOI: 10.1016/j.chembiol.2011.03.013  0.56
2011 Sleiman SF, Langley BC, Basso M, Berlin J, Xia L, Payappilly JB, Kharel MK, Guo H, Marsh JL, Thompson LM, Mahishi L, Ahuja P, MacLellan WR, Geschwind DH, Coppola G, ... ... Ratan RR, et al. Mithramycin is a gene-selective Sp1 inhibitor that identifies a biological intersection between cancer and neurodegeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 6858-70. PMID 21543616 DOI: 10.1523/JNEUROSCI.0710-11.2011  0.56
2011 Qin L, Kim E, Ratan R, Lee FS, Cho S. Genetic variant of BDNF (Val66Met) polymorphism attenuates stroke-induced angiogenic responses by enhancing anti-angiogenic mediator CD36 expression. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 775-83. PMID 21228186 DOI: 10.1523/JNEUROSCI.4547-10.2011  0.56
2011 Lee J, Kosaras B, Del Signore SJ, Cormier K, McKee A, Ratan RR, Kowall NW, Ryu H. Modulation of lipid peroxidation and mitochondrial function improves neuropathology in Huntington's disease mice. Acta Neuropathologica. 121: 487-98. PMID 21161248 DOI: 10.1007/s00401-010-0788-5  0.56
2011 Weller M, Stupp R, Ratan R, Goldfine A, Miller BL. Editorial introductions Current Opinion in Neurology. 24: ix-x. DOI: 10.1097/WCO.0b013e32834eb683  0.56
2011 Haskew-Layton RE, Ma TC, Ratan RR. Reply to Bell et al.: Nrf2-dependent and -independent mechanisms of astrocytic neuroprotection Proceedings of the National Academy of Sciences of the United States of America. 108: E3-E4. DOI: 10.1073/pnas.1016621108  0.56
2011 Ratan RR, Chao MV. Cell death in spinal cord injury – An evolving taxonomy with therapeutic promise Apoptosis: Physiology and Pathology. 164-175. DOI: 10.1017/CBO9780511976094.015  0.56
2011 Guo H, Aleyasin H, Howard S, Dickinson BC, Haskew-Layton R, Kobat D, Lin VS, Rivera D, Chang CJ, Ratan RR, Xu C. Two-photon imaging of intracellular hydrogen peroxide with a chemoselective fluorescence probe Optics Infobase Conference Papers 0.56
2010 Haskew-Layton RE, Payappilly JB, Smirnova NA, Ma TC, Chan KK, Murphy TH, Guo H, Langley B, Sultana R, Butterfield DA, Santagata S, Alldred MJ, Gazaryan IG, Bell GW, Ginsberg SD, ... Ratan RR, et al. Controlled enzymatic production of astrocytic hydrogen peroxide protects neurons from oxidative stress via an Nrf2-independent pathway. Proceedings of the National Academy of Sciences of the United States of America. 107: 17385-90. PMID 20855618 DOI: 10.1073/pnas.1003996107  0.56
2010 McConoughey SJ, Basso M, Niatsetskaya ZV, Sleiman SF, Smirnova NA, Langley BC, Mahishi L, Cooper AJ, Antonyak MA, Cerione RA, Li B, Starkov A, Chaturvedi RK, Beal MF, Coppola G, ... ... Ratan RR, et al. Inhibition of transglutaminase 2 mitigates transcriptional dysregulation in models of Huntington disease. Embo Molecular Medicine. 2: 349-70. PMID 20665636 DOI: 10.1002/emmm.201000084  0.56
2010 Ratan RR. Beyond neuroprotection to brain repair: exploring the next frontier in clinical neuroscience to expand the therapeutic window for stroke. Translational Stroke Research. 1: 71-3. PMID 20539747 DOI: 10.1007/s12975-010-0024-6  0.56
2010 Smirnova NA, Rakhman I, Moroz N, Basso M, Payappilly J, Kazakov S, Hernandez-Guzman F, Gaisina IN, Kozikowski AP, Ratan RR, Gazaryan IG. Utilization of an in vivo reporter for high throughput identification of branched small molecule regulators of hypoxic adaptation. Chemistry & Biology. 17: 380-91. PMID 20416509 DOI: 10.1016/j.chembiol.2010.03.008  0.56
2010 Akiba Y, Cave JW, Akiba N, Langley B, Ratan RR, Baker H. Histone deacetylase inhibitors de-repress tyrosine hydroxylase expression in the olfactory bulb and rostral migratory stream. Biochemical and Biophysical Research Communications. 393: 673-7. PMID 20170631 DOI: 10.1016/j.bbrc.2010.02.054  0.56
2010 Ma TC, Campana A, Lange PS, Lee HH, Banerjee K, Bryson JB, Mahishi L, Alam S, Giger RJ, Barnes S, Morris SM, Willis DE, Twiss JL, Filbin MT, Ratan RR. A large-scale chemical screen for regulators of the arginase 1 promoter identifies the soy isoflavone daidzeinas a clinically approved small molecule that can promote neuronal protection or regeneration via a cAMP-independent pathway. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 739-48. PMID 20071539 DOI: 10.1523/JNEUROSCI.5266-09.2010  0.56
2010 Gibson GE, Starkov A, Blass JP, Ratan RR, Beal MF. Cause and consequence: mitochondrial dysfunction initiates and propagates neuronal dysfunction, neuronal death and behavioral abnormalities in age-associated neurodegenerative diseases. Biochimica Et Biophysica Acta. 1802: 122-34. PMID 19715758 DOI: 10.1016/j.bbadis.2009.08.010  0.56
2010 Niatsetskaya Z, Basso M, Speer RE, McConoughey SJ, Coppola G, Ma TC, Ratan RR. HIF prolyl hydroxylase inhibitors prevent neuronal death induced by mitochondrial toxins: therapeutic implications for Huntington's disease and Alzheimer's disease. Antioxidants & Redox Signaling. 12: 435-43. PMID 19659431 DOI: 10.1089/ars.2009.2800  0.56
2010 Gazaryan IG, Ratan RR. Oxidative Damage in Neurodegeneration and Injury Encyclopedia of Neuroscience. 327-336. DOI: 10.1016/B978-008045046-9.00521-0  0.56
2009 Rivieccio MA, Brochier C, Willis DE, Walker BA, D'Annibale MA, McLaughlin K, Siddiq A, Kozikowski AP, Jaffrey SR, Twiss JL, Ratan RR, Langley B. HDAC6 is a target for protection and regeneration following injury in the nervous system. Proceedings of the National Academy of Sciences of the United States of America. 106: 19599-604. PMID 19884510 DOI: 10.1073/pnas.0907935106  0.56
2009 Ratan RR. Epigenetics and the nervous system: epiphenomenon or missing piece of the neurotherapeutic puzzle? The Lancet. Neurology. 8: 975-7. PMID 19833291 DOI: 10.1016/S1474-4422(09)70276-5  0.56
2009 Lee DW, Rajagopalan S, Siddiq A, Gwiazda R, Yang L, Beal MF, Ratan RR, Andersen JK. Inhibition of prolyl hydroxylase protects against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity: model for the potential involvement of the hypoxia-inducible factor pathway in Parkinson disease. The Journal of Biological Chemistry. 284: 29065-76. PMID 19679656 DOI: 10.1074/jbc.M109.000638  0.56
2009 Siddiq A, Aminova LR, Troy CM, Suh K, Messer Z, Semenza GL, Ratan RR. Selective inhibition of hypoxia-inducible factor (HIF) prolyl-hydroxylase 1 mediates neuroprotection against normoxic oxidative death via HIF- and CREB-independent pathways. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 8828-38. PMID 19587290 DOI: 10.1523/JNEUROSCI.1779-09.2009  0.56
2009 Sleiman SF, Basso M, Mahishi L, Kozikowski AP, Donohoe ME, Langley B, Ratan RR. Putting the 'HAT' back on survival signalling: the promises and challenges of HDAC inhibition in the treatment of neurological conditions. Expert Opinion On Investigational Drugs. 18: 573-84. PMID 19388875 DOI: 10.1517/13543780902810345  0.56
2009 McConoughey SJ, Niatsetskaya ZV, Pasternack R, Hils M, Ratan RR, Cooper AJ. A nonradioactive dot blot assay for transglutaminase activity. Analytical Biochemistry. 390: 91-3. PMID 19306836 DOI: 10.1016/j.ab.2009.03.022  0.56
2009 Ratan RR, Noble M. Novel multi-modal strategies to promote brain and spinal cord injury recovery. Stroke; a Journal of Cerebral Circulation. 40: S130-2. PMID 19064774 DOI: 10.1161/STROKEAHA.108.534933  0.56
2009 Speer RE, Ratan RR. Drug treatment for neurodegenerative disorders among the elderly: Re-engaging homeostatic programs Aging Health. 5: 133-136. DOI: 10.2217/ahe.09.11  0.56
2008 Ratan RR, Siddiq A, Aminova L, Langley B, McConoughey S, Karpisheva K, Lee HH, Carmichael T, Kornblum H, Coppola G, Geschwind DH, Hoke A, Smirnova N, Rink C, Roy S, et al. Small molecule activation of adaptive gene expression: tilorone or its analogs are novel potent activators of hypoxia inducible factor-1 that provide prophylaxis against stroke and spinal cord injury. Annals of the New York Academy of Sciences. 1147: 383-94. PMID 19076458 DOI: 10.1196/annals.1427.033  0.56
2008 Gibson GE, Ratan RR, Beal MF. Mitochondria and oxidative stress in neurodegenerative disorders. Preface. Annals of the New York Academy of Sciences. 1147: xi-xii. PMID 19076425 DOI: 10.1196/annals.1427.039  0.56
2008 Aminova LR, Siddiq A, Ratan RR. Antioxidants, HIF prolyl hydroxylase inhibitors or short interfering RNAs to BNIP3 or PUMA, can prevent prodeath effects of the transcriptional activator, HIF-1alpha, in a mouse hippocampal neuronal line. Antioxidants & Redox Signaling. 10: 1989-98. PMID 18774900 DOI: 10.1089/ars.2008.2039  0.56
2008 Lange PS, Chavez JC, Pinto JT, Coppola G, Sun CW, Townes TM, Geschwind DH, Ratan RR. ATF4 is an oxidative stress-inducible, prodeath transcription factor in neurons in vitro and in vivo. The Journal of Experimental Medicine. 205: 1227-42. PMID 18458112 DOI: 10.1084/jem.20071460  0.56
2008 Kalra L, Ratan RR. Advances in stroke regenerative medicine 2007. Stroke; a Journal of Cerebral Circulation. 39: 273-5. PMID 18187673 DOI: 10.1161/STROKEAHA.107.511972  0.56
2008 Langley B, D'Annibale MA, Suh K, Ayoub I, Tolhurst A, Bastan B, Yang L, Ko B, Fisher M, Cho S, Beal MF, Ratan RR. Pulse inhibition of histone deacetylases induces complete resistance to oxidative death in cortical neurons without toxicity and reveals a role for cytoplasmic p21(waf1/cip1) in cell cycle-independent neuroprotection. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 163-76. PMID 18171934 DOI: 10.1523/JNEUROSCI.3200-07.2008  0.56
2008 Siddiq A, Aminova LR, Ratan RR. Prolyl 4-hydroxylase activity-responsive transcription factors: from hydroxylation to gene expression and neuroprotection. Frontiers in Bioscience : a Journal and Virtual Library. 13: 2875-87. PMID 17981760 DOI: 10.2741/2892  0.56
2007 Ratan RR, Siddiq A, Smirnova N, Karpisheva K, Haskew-Layton R, McConoughey S, Langley B, Estevez A, Huerta PT, Volpe B, Roy S, Sen CK, Gazaryan I, Cho S, Fink M, et al. Harnessing hypoxic adaptation to prevent, treat, and repair stroke. Journal of Molecular Medicine (Berlin, Germany). 85: 1331-8. PMID 18043901 DOI: 10.1007/s00109-007-0283-1  0.56
2007 Gensert JM, Baranova OV, Weinstein DE, Ratan RR. CD81, a cell cycle regulator, is a novel target for histone deacetylase inhibition in glioma cells. Neurobiology of Disease. 26: 671-80. PMID 17481908 DOI: 10.1016/j.nbd.2007.03.008  0.56
2007 Siddiq A, Aminova LR, Ratan RR. Hypoxia inducible factor prolyl 4-hydroxylase enzymes: center stage in the battle against hypoxia, metabolic compromise and oxidative stress. Neurochemical Research. 32: 931-46. PMID 17342411 DOI: 10.1007/s11064-006-9268-7  0.56
2007 Kalra L, Ratan R. Recent advances in stroke rehabilitation 2006. Stroke; a Journal of Cerebral Circulation. 38: 235-7. PMID 17204671 DOI: 10.1161/01.STR.0000254944.91297.a3  0.56
2007 Volpe BT, Ratan RR. Clinical and neurobiological aspects of stroke recovery Neurobiology of Disease. 241-253. DOI: 10.1016/B978-012088592-3/50025-6  0.56
2006 Lee J, Kosaras B, Aleyasin H, Han JA, Park DS, Ratan RR, Kowall NW, Ferrante RJ, Lee SW, Ryu H. Role of cyclooxygenase-2 induction by transcription factor Sp1 and Sp3 in neuronal oxidative and DNA damage response. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 2375-7. PMID 17012241 DOI: 10.1096/fj.06-5957fje  0.56
2006 Estévez AG, Sahawneh MA, Lange PS, Bae N, Egea M, Ratan RR. Arginase 1 regulation of nitric oxide production is key to survival of trophic factor-deprived motor neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 8512-6. PMID 16914676 DOI: 10.1523/JNEUROSCI.0728-06.2006  0.56
2006 Khanna S, Roy S, Maurer M, Ratan RR, Sen CK. Oxygen-sensitive reset of hypoxia-inducible factor transactivation response: prolyl hydroxylases tune the biological normoxic set point. Free Radical Biology & Medicine. 40: 2147-54. PMID 16785028 DOI: 10.1016/j.freeradbiomed.2006.02.010  0.56
2006 Drottar M, Liberman MC, Ratan RR, Roberson DW. The histone deacetylase inhibitor sodium butyrate protects against cisplatin-induced hearing loss in guinea pigs. The Laryngoscope. 116: 292-6. PMID 16467722 DOI: 10.1097/01.mlg.0000197630.85208.36  0.56
2005 Siddiq A, Ayoub IA, Chavez JC, Aminova L, Shah S, LaManna JC, Patton SM, Connor JR, Cherny RA, Volitakis I, Bush AI, Langsetmo I, Seeley T, Gunzler V, Ratan RR. Hypoxia-inducible factor prolyl 4-hydroxylase inhibition. A target for neuroprotection in the central nervous system. The Journal of Biological Chemistry. 280: 41732-43. PMID 16227210 DOI: 10.1074/jbc.M504963200  0.56
2005 Lee J, Kim CH, Simon DK, Aminova LR, Andreyev AY, Kushnareva YE, Murphy AN, Lonze BE, Kim KS, Ginty DD, Ferrante RJ, Ryu H, Ratan RR. Mitochondrial cyclic AMP response element-binding protein (CREB) mediates mitochondrial gene expression and neuronal survival. The Journal of Biological Chemistry. 280: 40398-401. PMID 16207717 DOI: 10.1074/jbc.C500140200  0.56
2005 Ryu H, Lee J, Impey S, Ratan RR, Ferrante RJ. Antioxidants modulate mitochondrial PKA and increase CREB binding to D-loop DNA of the mitochondrial genome in neurons. Proceedings of the National Academy of Sciences of the United States of America. 102: 13915-20. PMID 16169904 DOI: 10.1073/pnas.0502878102  0.56
2005 Krasnikov BF, Kim SY, McConoughey SJ, Ryu H, Xu H, Stavrovskaya I, Iismaa SE, Mearns BM, Ratan RR, Blass JP, Gibson GE, Cooper AJ. Transglutaminase activity is present in highly purified nonsynaptosomal mouse brain and liver mitochondria. Biochemistry. 44: 7830-43. PMID 15909997 DOI: 10.1021/bi0500877  0.56
2005 Camelo S, Iglesias AH, Hwang D, Due B, Ryu H, Smith K, Gray SG, Imitola J, Duran G, Assaf B, Langley B, Khoury SJ, Stephanopoulos G, De Girolami U, Ratan RR, et al. Transcriptional therapy with the histone deacetylase inhibitor trichostatin A ameliorates experimental autoimmune encephalomyelitis. Journal of Neuroimmunology. 164: 10-21. PMID 15885809 DOI: 10.1016/j.jneuroim.2005.02.022  0.56
2005 Bardutzky J, Meng X, Bouley J, Duong TQ, Ratan R, Fisher M. Effects of intravenous dimethyl sulfoxide on ischemia evolution in a rat permanent occlusion model. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 25: 968-77. PMID 15744247 DOI: 10.1038/sj.jcbfm.9600095  0.56
2005 Langley B, Gensert JM, Beal MF, Ratan RR. Remodeling chromatin and stress resistance in the central nervous system: histone deacetylase inhibitors as novel and broadly effective neuroprotective agents. Current Drug Targets. Cns and Neurological Disorders. 4: 41-50. PMID 15723612 DOI: 10.2174/1568007053005091  0.56
2005 van Leyen K, Siddiq A, Ratan RR, Lo EH. Proteasome inhibition protects HT22 neuronal cells from oxidative glutamate toxicity. Journal of Neurochemistry. 92: 824-30. PMID 15686484 DOI: 10.1111/j.1471-4159.2004.02915.x  0.56
2005 Aminova LR, Chavez JC, Lee J, Ryu H, Kung A, Lamanna JC, Ratan RR. Prosurvival and prodeath effects of hypoxia-inducible factor-1alpha stabilization in a murine hippocampal cell line. The Journal of Biological Chemistry. 280: 3996-4003. PMID 15557337 DOI: 10.1074/jbc.M409223200  0.4
2005 Gardian G, Browne SE, Choi DK, Klivenyi P, Gregorio J, Kubilus JK, Ryu H, Langley B, Ratan RR, Ferrante RJ, Beal MF. Neuroprotective effects of phenylbutyrate in the N171-82Q transgenic mouse model of Huntington's disease. The Journal of Biological Chemistry. 280: 556-63. PMID 15494404 DOI: 10.1074/jbc.M410210200  0.56
2004 Ferrante RJ, Ryu H, Kubilus JK, D'Mello S, Sugars KL, Lee J, Lu P, Smith K, Browne S, Beal MF, Kristal BS, Stavrovskaya IG, Hewett S, Rubinsztein DC, Langley B, ... Ratan RR, et al. Chemotherapy for the brain: the antitumor antibiotic mithramycin prolongs survival in a mouse model of Huntington's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 10335-42. PMID 15548647 DOI: 10.1523/JNEUROSCI.2599-04.2004  0.56
2004 Ratan RR. cAMP response element binding protein family transcription factors: the Holy Grail of neurological therapeutics? Annals of Neurology. 56: 607-8. PMID 15505827 DOI: 10.1002/ana.20308  0.56
2004 Ratan RR, Siddiq A, Aminova L, Lange PS, Langley B, Ayoub I, Gensert J, Chavez J. Translation of ischemic preconditioning to the patient: prolyl hydroxylase inhibition and hypoxia inducible factor-1 as novel targets for stroke therapy. Stroke; a Journal of Cerebral Circulation. 35: 2687-9. PMID 15472113 DOI: 10.1161/01.STR.0000143216.85349.9e  0.56
2004 Lange PS, Langley B, Lu P, Ratan RR. Novel roles for arginase in cell survival, regeneration, and translation in the central nervous system. The Journal of Nutrition. 134: 2812S-2817S; discuss. PMID 15465791  0.56
2004 Langley B, Ratan RR. Oxidative stress-induced death in the nervous system: cell cycle dependent or independent? Journal of Neuroscience Research. 77: 621-9. PMID 15352208 DOI: 10.1002/jnr.20210  0.56
2004 Chin PC, Liu L, Morrison BE, Siddiq A, Ratan RR, Bottiglieri T, D'Mello SR. The c-Raf inhibitor GW5074 provides neuroprotection in vitro and in an animal model of neurodegeneration through a MEK-ERK and Akt-independent mechanism. Journal of Neurochemistry. 90: 595-608. PMID 15255937 DOI: 10.1111/j.1471-4159.2004.02530.x  0.56
2004 Selim MH, Ratan RR. The role of iron neurotoxicity in ischemic stroke. Ageing Research Reviews. 3: 345-53. PMID 15231241 DOI: 10.1016/j.arr.2004.04.001  0.56
2004 Boeshore KL, Schreiber RC, Vaccariello SA, Sachs HH, Salazar R, Lee J, Ratan RR, Leahy P, Zigmond RE. Novel changes in gene expression following axotomy of a sympathetic ganglion: a microarray analysis. Journal of Neurobiology. 59: 216-35. PMID 15085539 DOI: 10.1002/neu.10308  0.56
2003 Ferrante RJ, Kubilus JK, Lee J, Ryu H, Beesen A, Zucker B, Smith K, Kowall NW, Ratan RR, Luthi-Carter R, Hersch SM. Histone deacetylase inhibition by sodium butyrate chemotherapy ameliorates the neurodegenerative phenotype in Huntington's disease mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 9418-27. PMID 14561870  0.56
2003 Ratan RR. Mining genome databases for therapeutic gold: SIM2 is a novel target for treatment of solid tumors. Trends in Pharmacological Sciences. 24: 508-10. PMID 14559401 DOI: 10.1016/S0165-6147(03)00228-1  0.56
2003 Khanna S, Roy S, Ryu H, Bahadduri P, Swaan PW, Ratan RR, Sen CK. Molecular basis of vitamin E action: tocotrienol modulates 12-lipoxygenase, a key mediator of glutamate-induced neurodegeneration. The Journal of Biological Chemistry. 278: 43508-15. PMID 12917400 DOI: 10.1074/jbc.M307075200  0.56
2003 Schneck MJ, Blass JP, Ratan RR. "Silent" strokes and dementia [5] (multiple letters) New England Journal of Medicine. 349: 96. PMID 12840103 DOI: 10.1056/NEJMc031035  0.56
2003 Lehnardt S, Massillon L, Follett P, Jensen FE, Ratan R, Rosenberg PA, Volpe JJ, Vartanian T. Activation of innate immunity in the CNS triggers neurodegeneration through a Toll-like receptor 4-dependent pathway. Proceedings of the National Academy of Sciences of the United States of America. 100: 8514-9. PMID 12824464 DOI: 10.1073/pnas.1432609100  0.56
2003 Ryu H, Lee J, Zaman K, Kubilis J, Ferrante RJ, Ross BD, Neve R, Ratan RR. Sp1 and Sp3 are oxidative stress-inducible, antideath transcription factors in cortical neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 3597-606. PMID 12736330  0.56
2003 Blass JP, Ratan RR. "Silent" strokes and dementia. The New England Journal of Medicine. 348: 1277-8. PMID 12660392 DOI: 10.1056/NEJMe030017  0.56
2003 Lee J, Ryu H, Ferrante RJ, Morris SM, Ratan RR. Translational control of inducible nitric oxide synthase expression by arginine can explain the arginine paradox. Proceedings of the National Academy of Sciences of the United States of America. 100: 4843-8. PMID 12655043 DOI: 10.1073/pnas.0735876100  0.56
2003 Ryu H, Lee J, Olofsson BA, Mwidau A, Dedeoglu A, Escudero M, Flemington E, Azizkhan-Clifford J, Ferrante RJ, Ratan RR, Deodoglu A. Histone deacetylase inhibitors prevent oxidative neuronal death independent of expanded polyglutamine repeats via an Sp1-dependent pathway. Proceedings of the National Academy of Sciences of the United States of America. 100: 4281-6. PMID 12640146 DOI: 10.1073/pnas.0737363100  0.56
2003 Fisher M, Ratan R. New perspectives on developing acute stroke therapy. Annals of Neurology. 53: 10-20. PMID 12509843 DOI: 10.1002/ana.10407  0.56
2002 Dedeoglu A, Kubilus JK, Jeitner TM, Matson SA, Bogdanov M, Kowall NW, Matson WR, Cooper AJ, Ratan RR, Beal MF, Hersch SM, Ferrante RJ. Therapeutic effects of cystamine in a murine model of Huntington's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 8942-50. PMID 12388601  0.56
2002 Cai D, Deng K, Mellado W, Lee J, Ratan RR, Filbin MT. Arginase I and polyamines act downstream from cyclic AMP in overcoming inhibition of axonal growth MAG and myelin in vitro. Neuron. 35: 711-9. PMID 12194870 DOI: 10.1016/S0896-6273(02)00826-7  0.56
2002 Ratan RR, Ryu H, Lee J, Mwidau A, Neve RL. In vitro model of oxidative stress in cortical neurons. Methods in Enzymology. 352: 183-90. PMID 12125346 DOI: 10.1016/S0076-6879(02)52018-8  0.56
2001 Chatterjee S, Zaman K, Ryu H, Conforto A, Ratan RR. Sequence-selective DNA binding drugs mithramycin A and chromomycin A3 are potent inhibitors of neuronal apoptosis induced by oxidative stress and DNA damage in cortical neurons. Annals of Neurology. 49: 345-54. PMID 11261509 DOI: 10.1002/ana.71  0.56
2001 Högnason T, Chatterjee S, Vartanian T, Ratan RR, Ernewein KM, Habib AA. Epidermal growth factor receptor induced apoptosis: potentiation by inhibition of Ras signaling. Febs Letters. 491: 9-15. PMID 11226409 DOI: 10.1016/S0014-5793(01)02166-4  0.56
2001 Sipos EP, Witham TF, Ratan R, Burger PC, Baraban J, Li KW, Piantadosi S, Brem H. L-buthionine sulfoximine potentiates the antitumor effect of 4-hydroperoxycyclophosphamide when administered locally in a rat glioma model. Neurosurgery. 48: 392-400. PMID 11220384  0.56
2001 Habib AA, Chatterjee S, Park SK, Ratan RR, Lefebvre S, Vartanian T. The epidermal growth factor receptor engages receptor interacting protein and nuclear factor-kappa B (NF-kappa B)-inducing kinase to activate NF-kappa B. Identification of a novel receptor-tyrosine kinase signalosome. The Journal of Biological Chemistry. 276: 8865-74. PMID 11116146 DOI: 10.1074/jbc.M008458200  0.56
2000 Sorond FA, Ratan RR. Ironing-out mechanisms of neuronal injury under hypoxic-ischemic conditions and potential role of iron chelators as neuroprotective agents. Antioxidants & Redox Signaling. 2: 421-36. PMID 11229356 DOI: 10.1089/15230860050192206  0.56
1999 Nargi JL, Ratan RR, Griffin DE. p53-independent inhibition of proliferation and p21(WAF1/Cip1)-modulated induction of cell death by the antioxidants N-acetylcysteine and vitamin E. Neoplasia (New York, N.Y.). 1: 544-56. PMID 10935502  0.56
1999 Zaman K, Ryu H, Hall D, O'Donovan K, Lin KI, Miller MP, Marquis JC, Baraban JM, Semenza GL, Ratan RR. Protection from oxidative stress-induced apoptosis in cortical neuronal cultures by iron chelators is associated with enhanced DNA binding of hypoxia-inducible factor-1 and ATF-1/CREB and increased expression of glycolytic enzymes, p21(waf1/cip1), and erythropoietin. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 9821-30. PMID 10559391  0.56
1999 Lin KI, Pasinelli P, Brown RH, Hardwick JM, Ratan RR. Decreased intracellular superoxide levels activate Sindbis virus-induced apoptosis. The Journal of Biological Chemistry. 274: 13650-5. PMID 10224137 DOI: 10.1074/jbc.274.19.13650  0.56
1998 Lin KI, Baraban JM, Ratan RR. Inhibition versus induction of apoptosis by proteasome inhibitors depends on concentration. Cell Death and Differentiation. 5: 577-83. PMID 10200512 DOI: 10.1038/sj.cdd.4400384  0.56
1998 Lin KI, Chattopadhyay N, Bai M, Alvarez R, Dang CV, Baraban JM, Brown EM, Ratan RR. Elevated extracellular calcium can prevent apoptosis via the calcium-sensing receptor. Biochemical and Biophysical Research Communications. 249: 325-31. PMID 9712695 DOI: 10.1006/bbrc.1998.9124  0.56
1998 Lin KI, DiDonato JA, Hoffmann A, Hardwick JM, Ratan RR. Suppression of steady-state, but not stimulus-induced NF-kappaB activity inhibits alphavirus-induced apoptosis. The Journal of Cell Biology. 141: 1479-87. PMID 9647642 DOI: 10.1083/jcb.141.7.1479  0.56
1998 Esch F, Lin KI, Hills A, Zaman K, Baraban JM, Chatterjee S, Rubin L, Ash DE, Ratan RR. Purification of a multipotent antideath activity from bovine liver and its identification as arginase: nitric oxide-independent inhibition of neuronal apoptosis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 4083-95. PMID 9592089  0.56
1998 Habib AA, Högnason T, Ren J, Stefánsson K, Ratan RR. The epidermal growth factor receptor associates with and recruits phosphatidylinositol 3-kinase to the platelet-derived growth factor beta receptor. The Journal of Biological Chemistry. 273: 6885-91. PMID 9506992 DOI: 10.1074/jbc.273.12.6885  0.56
1997 Togashi H, Sasaki M, Frohman E, Taira E, Ratan RR, Dawson TM, Dawson VL. Neuronal (type I) nitric oxide synthase regulates nuclear factor kappaB activity and immunologic (type II) nitric oxide synthase expression. Proceedings of the National Academy of Sciences of the United States of America. 94: 2676-80. PMID 9122255 DOI: 10.1073/pnas.94.6.2676  0.56
1996 Ratan RR, Lee PJ, Baraban JM. Serum deprivation inhibits glutathione depletion-induced death in embryonic cortical neurons: evidence against oxidative stress as a final common mediator of neuronal apoptosis. Neurochemistry International. 29: 153-7. PMID 8837044 DOI: 10.1016/0197-0186(95)00115-8  0.56
1995 Lin KI, Lee SH, Narayanan R, Baraban JM, Hardwick JM, Ratan RR. Thiol agents and Bcl-2 identify an alphavirus-induced apoptotic pathway that requires activation of the transcription factor NF-kappa B. The Journal of Cell Biology. 131: 1149-61. PMID 8522579 DOI: 10.1083/jcb.131.5.1149  0.56
1995 Ratan RR, Baraban JM. Apoptotic death in an in vitro model of neuronal oxidative stress. Clinical and Experimental Pharmacology & Physiology. 22: 309-10. PMID 7671450  0.56
1994 Ratan RR, Murphy TH, Baraban JM. Macromolecular synthesis inhibitors prevent oxidative stress-induced apoptosis in embryonic cortical neurons by shunting cysteine from protein synthesis to glutathione. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 14: 4385-92. PMID 8027786  0.56
1994 Ratan RR, Murphy TH, Baraban JM. Oxidative stress induces apoptosis in embryonic cortical neurons. Journal of Neurochemistry. 62: 376-9. PMID 7903353  0.56
1989 Peterson C, Ratan R, Shelanski M, Goldman J. Changes in calcium homeostasis during aging and Alzheimer's disease. Annals of the New York Academy of Sciences. 568: 262-70. PMID 2629585 DOI: 10.1111/j.1749-6632.1989.tb12515.x  0.56
1988 Ratan RR, Maxfield FR, Shelanski ML. Long-lasting and rapid calcium changes during mitosis. The Journal of Cell Biology. 107: 993-9. PMID 3417787  0.56
1988 Peterson C, Ratan RR, Shelanski ML, Goldman JE. Altered response of fibroblasts from aged and Alzheimer donors to drugs that elevate cytosolic free calcium. Neurobiology of Aging. 9: 261-6. PMID 3398992 DOI: 10.1016/S0197-4580(88)80063-0  0.56
1986 Keith CH, Bajer AS, Ratan R, Maxfield FR, Shelanski ML. Calcium and calmodulin in the regulation of the microtubular cytoskeleton. Annals of the New York Academy of Sciences. 466: 375-91. PMID 3524372  0.56
1986 Peterson C, Ratan RR, Shelanski ML, Goldman JE. Cytosolic free calcium and cell spreading decrease in fibroblasts from aged and Alzheimer donors. Proceedings of the National Academy of Sciences of the United States of America. 83: 7999-8001. PMID 3464016  0.56
1986 Ratan RR, Shelanski ML, Maxfield FR. Transition from metaphase to anaphase is accompanied by local changes in cytoplasmic free calcium in Pt K2 kidney epithelial cells. Proceedings of the National Academy of Sciences of the United States of America. 83: 5136-40. PMID 3460085  0.56
1985 Keith CH, Ratan R, Maxfield FR, Bajer A, Shelanski ML. Local cytoplasmic calcium gradients in living mitotic cells. Nature. 316: 848-50. PMID 4033782 DOI: 10.1038/316848a0  0.56
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