| Year |
Citation |
Score |
| 2020 |
Clement A, Wiborg O, Asuni AA. Steps Towards Developing Effective Treatments for Neuropsychiatric Disturbances in Alzheimer's Disease: Insights From Preclinical Models, Clinical Data, and Future Directions. Frontiers in Aging Neuroscience. 12: 56. PMID 32210790 DOI: 10.3389/Fnagi.2020.00056 |
0.38 |
|
| 2019 |
Bastrup J, Kastaniegaard K, Asuni AA, Volbracht C, Stensballe A. Proteomic and Unbiased Post-Translational Modification Profiling of Amyloid Plaques and Surrounding Tissue in a Transgenic Mouse Model of Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 31771055 DOI: 10.3233/Jad-190652 |
0.425 |
|
| 2019 |
Pitera AP, Asuni AA, O'Connor V, Deinhardt K. Pathogenic tau does not drive activation of the unfolded protein response. The Journal of Biological Chemistry. PMID 31053641 DOI: 10.1074/Jbc.Ra119.008263 |
0.621 |
|
| 2019 |
Pankiewicz JE, Asuni AA, Reich C, Baquero-Buitrago J, Sadowski MJ. P2-056: TARGETING APP TRANSLATION FOR ALZHEIMER'S DISEASE THERAPY Alzheimer's & Dementia. 15: P592-P593. DOI: 10.1016/J.Jalz.2019.06.2463 |
0.339 |
|
| 2018 |
Rosenqvist N, Asuni AA, Andersson CR, Christensen S, Daechsel JA, Egebjerg J, Falsig J, Helboe L, Jul P, Kartberg F, Pedersen LØ, Sigurdsson EM, Sotty F, Skjødt K, Stavenhagen JB, et al. Highly specific and selective anti-pS396-tau antibody C10.2 targets seeding-competent tau. Alzheimer's & Dementia (New York, N. Y.). 4: 521-534. PMID 30386817 DOI: 10.1016/J.Trci.2018.09.005 |
0.403 |
|
| 2018 |
Sumner IL, Edwards RA, Asuni AA, Teeling JL. Antibody Engineering for Optimized Immunotherapy in Alzheimer's Disease. Frontiers in Neuroscience. 12: 254. PMID 29740272 DOI: 10.3389/Fnins.2018.00254 |
0.405 |
|
| 2017 |
Clement A, Mitchelmore C, Andersson DR, Asuni AA. Cerebrospinal fluid neurofilament light chain as a biomarker of neurodegeneration in the Tg4510 and MitoPark mouse models. Neuroscience. 354: 101-109. PMID 28461218 DOI: 10.1016/J.Neuroscience.2017.04.030 |
0.327 |
|
| 2017 |
Pankiewicz JE, Asuni AA, Baquero-Buitrago J, Sadowski MJ. [P2-060]: CHARACTERIZATION OF A SMALL-MOLECULE APP TRANSLATION INHIBITOR FOR ALZHEIMER's DISEASE PREVENTION AND THERAPY Alzheimer's & Dementia. 13: P627-P628. DOI: 10.1016/J.Jalz.2017.06.709 |
0.328 |
|
| 2016 |
Clement A, Mitchelmore C, Andersson D, Asuni AA. P2-103: Altered Expression Levels of Neurofilaments in Brain and CSF in TG4510 and Mitopark MICE Alzheimer's & Dementia. 12: P651-P651. DOI: 10.1016/J.Jalz.2016.06.1309 |
0.302 |
|
| 2015 |
Asuni AA, Guridi M, Sanchez S, Sadowski MJ. Antioxidant peroxiredoxin 6 protein rescues toxicity due to oxidative stress and cellular hypoxia in vitro, and attenuates prion-related pathology in vivo. Neurochemistry International. 90: 152-65. PMID 26265052 DOI: 10.1016/J.Neuint.2015.08.006 |
0.37 |
|
| 2015 |
Amin J, Paquet C, Baker A, Asuni AA, Love S, Holmes C, Hugon J, Nicoll JA, Boche D. Effect of amyloid-β (Aβ) immunization on hyperphosphorylated tau: a potential role for glycogen synthase kinase (GSK)-3β. Neuropathology and Applied Neurobiology. 41: 445-57. PMID 25486988 DOI: 10.1111/Nan.12205 |
0.602 |
|
| 2015 |
Hallaq R, Volpicelli F, Cuchillo-Ibanez I, Hooper C, Mizuno K, Uwanogho D, Causevic M, Asuni A, To A, Soriano S, Giese KP, Lovestone S, Killick R. The Notch intracellular domain represses CRE-dependent transcription. Cellular Signalling. 27: 621-9. PMID 25479589 DOI: 10.1016/J.Cellsig.2014.11.034 |
0.42 |
|
| 2014 |
Asuni AA, Pankiewicz JE, Sadowski MJ. Reply: To PMID 24687915. Annals of Neurology. 76: 630-1. PMID 25154327 DOI: 10.1002/Ana.24253 |
0.333 |
|
| 2014 |
Pankiewicz JE, Guridi M, Kim J, Asuni AA, Sanchez S, Sullivan PM, Holtzman DM, Sadowski MJ. Blocking the apoE/Aβ interaction ameliorates Aβ-related pathology in APOE ε2 and ε4 targeted replacement Alzheimer model mice. Acta Neuropathologica Communications. 2: 75. PMID 24972680 DOI: 10.1186/Preaccept-1147957959132865 |
0.404 |
|
| 2014 |
Asuni AA, Guridi M, Pankiewicz JE, Sanchez S, Sadowski MJ. Modulation of amyloid precursor protein expression reduces β-amyloid deposition in a mouse model. Annals of Neurology. 75: 684-99. PMID 24687915 DOI: 10.1002/Ana.24149 |
0.403 |
|
| 2014 |
Asuni AA, Gray B, Bailey J, Skipp P, Perry VH, O'Connor V. Analysis of the hippocampal proteome in ME7 prion disease reveals a predominant astrocytic signature and highlights the brain-restricted production of clusterin in chronic neurodegeneration. The Journal of Biological Chemistry. 289: 4532-45. PMID 24366862 DOI: 10.1074/Jbc.M113.502690 |
0.669 |
|
| 2014 |
Collcutt AW, Teeling JL, Asuni AA. The impact of neuroinflammation on tau pathology in healthy aging and neurodegeneration Journal of Neuroimmunology. 275: 144. DOI: 10.1016/J.Jneuroim.2014.08.386 |
0.313 |
|
| 2013 |
Kuszczyk MA, Sanchez S, Pankiewicz J, Kim J, Duszczyk M, Guridi M, Asuni AA, Sullivan PM, Holtzman DM, Sadowski MJ. Blocking the interaction between apolipoprotein E and Aβ reduces intraneuronal accumulation of Aβ and inhibits synaptic degeneration. The American Journal of Pathology. 182: 1750-68. PMID 23499462 DOI: 10.1016/J.Ajpath.2013.01.034 |
0.408 |
|
| 2013 |
Asuni AA, Pankiewicz JE, Sadowski MJ. Differential molecular chaperone response associated with various mouse adapted scrapie strains. Neuroscience Letters. 538: 26-31. PMID 23370284 DOI: 10.1016/J.Neulet.2013.01.027 |
0.372 |
|
| 2012 |
Asuni A, Lin XK, Guridi M, Sanchez S, Almassian B, Sadowski M. An APP translation modulator ARN2966 reduces BETA-AMYLOID deposition and prevents memory deficits in ALZHEIMER'S DISEASE transgenic mice Alzheimers & Dementia. 8. DOI: 10.1016/J.Jalz.2013.08.025 |
0.379 |
|
| 2012 |
Asuni A, Ormazabal MG, Sanchez S, Sadowski M. Loss of antioxidant peroxiredoxin 6 protein exacerbates in vivo neurodegeneration in prion disease Alzheimers & Dementia. 8: 477. DOI: 10.1016/J.Jalz.2012.05.1287 |
0.365 |
|
| 2011 |
Verdier J, Mestre-Frances N, Devau G, Trouche S, Abdel-Rassoul R, Lautier C, Asuni A, Boutajangout A, Sigurdsson E. P4-476: Aging and genetics in the lemurian primate Microcebus murinus
: A useful approach for Alzheimer's disease studies Alzheimer's & Dementia. 7: e76-e76. DOI: 10.1016/J.Jalz.2011.09.169 |
0.309 |
|
| 2011 |
Asuni A, Duszczyk M, Sadowski M. Hyperglycemia increases amyloid accumulation and exacerbates cerebrovascular pathology in Alzheimer's disease model animals Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.05.1441 |
0.412 |
|
| 2011 |
Asuni A, Pankiewicz J, Kuszczyk M, Lin XK, Almassian B, Sadowski M. Pyridin-2-ylmethylamine derivatives as novel inhibitors of aβ aggregation and toxicity Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.05.1369 |
0.314 |
|
| 2011 |
Šišková Z, Perry VH, Asuni AA. Prion protein misfolding at the synapse Folding For the Synapse. 289-312. DOI: 10.1007/978-1-4419-7061-9-15 |
0.46 |
|
| 2010 |
Sisková Z, Mahad DJ, Pudney C, Campbell G, Cadogan M, Asuni A, O'Connor V, Perry VH. Morphological and functional abnormalities in mitochondria associated with synaptic degeneration in prion disease. The American Journal of Pathology. 177: 1411-21. PMID 20651247 DOI: 10.2353/Ajpath.2010.091037 |
0.64 |
|
| 2010 |
Asuni AA, Perry VH, O'Connor V. Change in tau phosphorylation associated with neurodegeneration in the ME7 model of prion disease. Biochemical Society Transactions. 38: 545-51. PMID 20298219 DOI: 10.1042/Bst0380545 |
0.685 |
|
| 2010 |
Asuni AA, Hilton K, Siskova Z, Lunnon K, Reynolds R, Perry VH, O'Connor V. Alpha-synuclein deficiency in the C57BL/6JOlaHsd strain does not modify disease progression in the ME7-model of prion disease. Neuroscience. 165: 662-74. PMID 19879926 DOI: 10.1016/J.Neuroscience.2009.10.047 |
0.644 |
|
| 2009 |
Boutajangout A, Goni F, Knudsen E, Schreiber F, Asuni A, Quartermain D, Frangione B, Chabalgoity A, Wisniewski T, Sigurdsson EM. Diminished amyloid-beta burden in Tg2576 mice following a prophylactic oral immunization with a salmonella-based amyloid-beta derivative vaccine. Journal of Alzheimer's Disease : Jad. 18: 961-72. PMID 19749432 DOI: 10.3233/Jad-2009-1204 |
0.371 |
|
| 2009 |
Trouche SG, Asuni A, Rouland S, Wisniewski T, Frangione B, Verdier JM, Sigurdsson EM, Mestre-Francés N. Antibody response and plasma Abeta1-40 levels in young Microcebus murinus primates immunized with Abeta1-42 and its derivatives. Vaccine. 27: 957-64. PMID 19114076 DOI: 10.1016/J.Vaccine.2008.12.012 |
0.328 |
|
| 2008 |
Asuni AA, Cunningham C, Vigneswaran P, Perry VH, O'Connor V. Unaltered SNARE complex formation in an in vivo model of prion disease. Brain Research. 1233: 1-7. PMID 18706894 DOI: 10.1016/J.Brainres.2008.07.083 |
0.642 |
|
| 2008 |
Asuni AA, Lidwell K, O'Connor V. Biochemical evidence for the differential association of metabotropic glutamate receptors within synaptic complexes. Neuroscience Letters. 444: 27-30. PMID 18706475 DOI: 10.1016/J.Neulet.2008.08.009 |
0.55 |
|
| 2008 |
Quraishe S, Asuni A, Boelens WC, O'Connor V, Wyttenbach A. Expression of the small heat shock protein family in the mouse CNS: differential anatomical and biochemical compartmentalization. Neuroscience. 153: 483-91. PMID 18384969 DOI: 10.1016/J.Neuroscience.2008.01.058 |
0.585 |
|
| 2008 |
Sigurdsson EM, Wadghiri YZ, Mosconi L, Blind JA, Knudsen E, Asuni A, Scholtzova H, Tsui WH, Li Y, Sadowski M, Turnbull DH, de Leon MJ, Wisniewski T. A non-toxic ligand for voxel-based MRI analysis of plaques in AD transgenic mice. Neurobiology of Aging. 29: 836-47. PMID 17291630 DOI: 10.1016/J.Neurobiolaging.2006.12.018 |
0.352 |
|
| 2007 |
Asuni AA, Boutajangout A, Quartermain D, Sigurdsson EM. Immunotherapy targeting pathological tau conformers in a tangle mouse model reduces brain pathology with associated functional improvements. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 9115-29. PMID 17715348 DOI: 10.1523/Jneurosci.2361-07.2007 |
0.415 |
|
| 2006 |
Asuni AA, Hooper C, Reynolds CH, Lovestone S, Anderton BH, Killick R. GSK3alpha exhibits beta-catenin and tau directed kinase activities that are modulated by Wnt. The European Journal of Neuroscience. 24: 3387-92. PMID 17229088 DOI: 10.1111/J.1460-9568.2006.05243.X |
0.465 |
|
| 2006 |
Asuni AA, Boutajangout A, Scholtzova H, Knudsen E, Li YS, Quartermain D, Frangione B, Wisniewski T, Sigurdsson EM. Vaccination of Alzheimer's model mice with Abeta derivative in alum adjuvant reduces Abeta burden without microhemorrhages. The European Journal of Neuroscience. 24: 2530-42. PMID 17100841 DOI: 10.1111/J.1460-9568.2006.05149.X |
0.359 |
|
| 2006 |
Bastrup J, Asuni AA, Volbracht C, Stensballe A. IC-P-175: INVESTIGATION OF THE AMYLOID PLAQUE PEPTIDOME IN A MOUSE MODEL OF ALZHEIMER'S DISEASE USING MALDI IMAGING Alzheimer's & Dementia. 14: P148-P148. DOI: 10.1016/J.Jalz.2018.06.2242 |
0.369 |
|
| 2006 |
Boutajangout A, Asuni AA, Scholtzova H, Knudsen E, Li Y, Quartermain D, Frangione B, Wisniewski T, Sigurdsson EM. P4-316: Aβ derivative vaccine does not cause brain microhemorrhages in Tg2576 mice and its effectiveness is age-dependent Alzheimer's & Dementia. 2: S609-S610. DOI: 10.1016/J.Jalz.2006.05.2057 |
0.316 |
|
| 2006 |
Trouche S, Asuni A, Wisniewski T, Frangione B, Sigurdsson E, Verdier J, Mestre-Frances N. P4-290: Immunization with Aβ derivatives in Microcebus murinus
: A primate lemurian model of Alzheimer's disease Alzheimer's & Dementia. 2: S602-S602. DOI: 10.1016/J.Jalz.2006.05.2029 |
0.383 |
|
| 2005 |
Sigurdsson E, Wadghiri Y, Knudsen E, Asuni A, Sadowski M, Turnbull D, Wisniewski T. [O1-03-05]: In vivo detection of amyloid plaques in AD transgenic mice using gadolinium labeled ligands by MRI Alzheimer's & Dementia. 1: S84-S84. DOI: 10.1016/J.Jalz.2005.06.296 |
0.332 |
|
| 2004 |
Sigurdsson EM, Knudsen E, Asuni A, Fitzer-Attas C, Sage D, Quartermain D, Goni F, Frangione B, Wisniewski T. An attenuated immune response is sufficient to enhance cognition in an Alzheimer's disease mouse model immunized with amyloid-beta derivatives. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 6277-82. PMID 15254082 DOI: 10.1523/Jneurosci.1344-04.2004 |
0.383 |
|
| 2004 |
Saha AR, Hill J, Utton MA, Asuni AA, Ackerley S, Grierson AJ, Miller CC, Davies AM, Buchman VL, Anderton BH, Hanger DP. Parkinson's disease alpha-synuclein mutations exhibit defective axonal transport in cultured neurons. Journal of Cell Science. 117: 1017-24. PMID 14996933 DOI: 10.1242/Jcs.00967 |
0.327 |
|
| 2004 |
Mudher A, Shepherd D, Newman TA, Mildren P, Jukes JP, Squire A, Mears A, Drummond JA, Berg S, MacKay D, Asuni AA, Bhat R, Lovestone S. GSK-3beta inhibition reverses axonal transport defects and behavioural phenotypes in Drosophila. Molecular Psychiatry. 9: 522-30. PMID 14993907 DOI: 10.1038/Sj.Mp.4001483 |
0.525 |
|
| 2004 |
Asuni AA, Knudsen E, Frangione B, Wisniewski T, Sigurdsson EM. P4-375 Antibody mediated modulation of Aβ induced neurotoxicity in cell culture Neurobiology of Aging. 25: S581-S582. DOI: 10.1016/S0197-4580(04)81933-X |
0.309 |
|
| 2004 |
Sigurdsson EM, Wadghiri YZ, Blind JA, Knudsen E, Asuni AA, Sadowski M, Turnbull DH, Wisniewski T. O3-03-03 In vivo magnetic resonance imaging of amyloid plaques in mice with a non-toxic Aβ derivative Neurobiology of Aging. 25. DOI: 10.1016/S0197-4580(04)80193-3 |
0.311 |
|
| 2003 |
Ljungberg MC, Asuni A, Pearce J, Dayanandan R, März W, Hoffmann MM, Bertrand P, Siest G, Rupniak HT, Anderton BH, Huettinger M, Lovestone S. Apolipoprotein E (apoE) uptake and distribution in mammalian cell lines is dependent upon source of apoE and can be monitored in living cells. Neuroscience Letters. 341: 69-73. PMID 12676346 DOI: 10.1016/S0304-3940(03)00064-8 |
0.485 |
|
| 2002 |
Utton MA, Connell J, Asuni AA, van Slegtenhorst M, Hutton M, de Silva R, Lees AJ, Miller CC, Anderton BH. The slow axonal transport of the microtubule-associated protein tau and the transport rates of different isoforms and mutants in cultured neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 6394-400. PMID 12151518 DOI: 10.1523/Jneurosci.22-15-06394.2002 |
0.318 |
|
| 2002 |
Ljungberg MC, Dayanandan R, Asuni A, Rupniak TH, Anderton BH, Lovestone S. Truncated apoE forms tangle-like structures in a neuronal cell line. Neuroreport. 13: 867-70. PMID 11997703 DOI: 10.1097/00001756-200205070-00026 |
0.517 |
|
| 2001 |
Killick R, Pollard CC, Asuni AA, Mudher AK, Richardson JC, Rupniak HT, Sheppard PW, Varndell IM, Brion JP, Levey AI, Levy OA, Vestling M, Cowburn R, Lovestone S, Anderton BH. Presenilin 1 independently regulates beta-catenin stability and transcriptional activity. The Journal of Biological Chemistry. 276: 48554-61. PMID 11606587 DOI: 10.1074/Jbc.M108332200 |
0.423 |
|
| 2001 |
Mudher A, Chapman S, Richardson J, Asuni A, Gibb G, Pollard C, Killick R, Iqbal T, Raymond L, Varndell I, Sheppard P, Makoff A, Gower E, Soden PE, Lewis P, et al. Dishevelled regulates the metabolism of amyloid precursor protein via protein kinase C/mitogen-activated protein kinase and c-Jun terminal kinase. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 4987-95. PMID 11438574 DOI: 10.1523/Jneurosci.21-14-04987.2001 |
0.437 |
|
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