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Blas Frangione, MD, Universidad de Buenos Aires Escuela de Medicina, PhD - Publications

Affiliations: 
Pathology and Psychiatry New York University, New York, NY, United States 
Area:
http://www.researchprofiles.collexis.com/jad/expert.asp?u_id=22
Website:
http://pathology.med.nyu.edu/people/faculty/frangione-blas
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Year Citation  Score
2019 Franklin EC, Pras M, Levin M, Frangione B. The partial amino acid sequence of the major low molecular weight component of two human amyloid fibrils. Febs Letters. 22: 121-123. PMID 11946577 DOI: 10.1016/0014-5793(72)80235-7  0.35
2015 Tarasoff-Conway JM, Carare RO, Osorio RS, Glodzik L, Butler T, Fieremans E, Axel L, Rusinek H, Nicholson C, Zlokovic BV, Frangione B, Blennow K, Ménard J, Zetterberg H, Wisniewski T, et al. Clearance systems in the brain-implications for Alzheimer disease. Nature Reviews. Neurology. PMID 26195256 DOI: 10.1038/Nrneurol.2015.119  0.429
2013 Halliday MR, Pomara N, Sagare AP, Mack WJ, Frangione B, Zlokovic BV. Relationship between cyclophilin a levels and matrix metalloproteinase 9 activity in cerebrospinal fluid of cognitively normal apolipoprotein e4 carriers and blood-brain barrier breakdown. Jama Neurology. 70: 1198-200. PMID 24030206 DOI: 10.1001/Jamaneurol.2013.3841  0.316
2010 Tomidokoro Y, Tamaoka A, Holton JL, Lashley T, Frangione B, Revesz T, Rostagno A, Ghiso J. PYROGLUTAMATE FORMATION AT THE N-TERMINI OF ABRI MOLECULES IN FAMILIAL BRITISH DEMENTIA IS NOT RESTRICTED TO THE CENTRAL NERVOUS SYSTEM. Hirosaki Igaku = Hirosaki Medical Journal. 61: S262-S269. PMID 21037969  0.316
2010 Ghiso J, Tomidokoro Y, Revesz T, Frangione B, Rostagno A. CEREBRAL AMYLOID ANGIOPATHY AND ALZHEIMER'S DISEASE. Hirosaki Igaku = Hirosaki Medical Journal. 61: S111-S124. PMID 21037967  0.328
2010 Tomidokoro Y, Rostagno A, Neubert TA, Lu Y, Rebeck GW, Frangione B, Greenberg SM, Ghiso J. Iowa variant of familial Alzheimer's disease: accumulation of posttranslationally modified AbetaD23N in parenchymal and cerebrovascular amyloid deposits. The American Journal of Pathology. 176: 1841-54. PMID 20228223 DOI: 10.2353/Ajpath.2010.090636  0.474
2010 Osorio RS, Agüera-Ortiz L, de Leon MJ, Glodzik L, Ayappa I, Hussain A, Frangione B. P4-004: Abeta42 Cerebrospinal Fluid Decrease in Normal Adults With Sleep Complaints: A New Risk Factor for Alzheimer's Disease? Alzheimer's & Dementia. 6: e21-e22. DOI: 10.1016/J.Jalz.2010.08.065  0.308
2009 Boutajangout A, Goni F, Knudsen E, Schreiber F, Asuni A, Quartermain D, Frangione B, Chabalgoity A, Wisniewski T, Sigurdsson EM. Diminished amyloid-beta burden in Tg2576 mice following a prophylactic oral immunization with a salmonella-based amyloid-beta derivative vaccine. Journal of Alzheimer's Disease : Jad. 18: 961-72. PMID 19749432 DOI: 10.3233/Jad-2009-1204  0.38
2009 Revesz T, Holton JL, Lashley T, Plant G, Frangione B, Rostagno A, Ghiso J. Genetics and molecular pathogenesis of sporadic and hereditary cerebral amyloid angiopathies. Acta Neuropathologica. 118: 115-30. PMID 19225789 DOI: 10.1007/S00401-009-0501-8  0.445
2009 Trouche SG, Asuni A, Rouland S, Wisniewski T, Frangione B, Verdier JM, Sigurdsson EM, Mestre-Francés N. Antibody response and plasma Abeta1-40 levels in young Microcebus murinus primates immunized with Abeta1-42 and its derivatives. Vaccine. 27: 957-64. PMID 19114076 DOI: 10.1016/J.Vaccine.2008.12.012  0.374
2009 Boutajangout A, Frangione B, Wisniewski T, Brion J, Sigurdsson EM. P4-049: Influence of presenilin mutation on tau pathology in a novel Alzheimer's disease mouse model Alzheimer's & Dementia. 5: P445-P446. DOI: 10.1016/J.Jalz.2009.04.919  0.365
2008 Lashley T, Revesz T, Plant G, Bandopadhyay R, Lees AJ, Frangione B, Wood NW, de Silva R, Ghiso J, Rostagno A, Holton JL. Expression of BRI2 mRNA and protein in normal human brain and familial British dementia: its relevance to the pathogenesis of disease. Neuropathology and Applied Neurobiology. 34: 492-505. PMID 18282158 DOI: 10.1111/J.1365-2990.2008.00935.X  0.36
2008 Trouche SG, Asuni A, Boutajangout A, Frangione B, Wisniewski T, Rouland S, Verdier J, Sigurdsson EM, Mestre-Frances N. P1-021: Neuropathological evaluation of the nonhuman primate microcebus murinus immunized with K6Aβ1-30, an Aβ derivative peptide Alzheimer's & Dementia. 4: T211-T211. DOI: 10.1016/J.Jalz.2008.05.606  0.328
2008 Boutajangout A, Frangione B, Brion J, Wisniewski T, Sigurdsson EM. O4-01-05: Presenilin 1 mutation promotes Tau phosphorylation and aggregation in a novel Alzheimer's disease mouse model Alzheimer's & Dementia. 4: T185-T185. DOI: 10.1016/J.Jalz.2008.05.504  0.372
2007 Westermark P, Benson MD, Buxbaum JN, Cohen AS, Frangione B, Ikeda S, Masters CL, Merlini G, Saraiva MJ, Sipe JD. A primer of amyloid nomenclature. Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis. 14: 179-83. PMID 17701465 DOI: 10.1080/13506120701460923  0.402
2007 Zanusso G, Polo A, Farinazzo A, Nonno R, Cardone F, Di Bari M, Ferrari S, Principe S, Gelati M, Fasoli E, Fiorini M, Prelli F, Frangione B, Tridente G, Bentivoglio M, et al. Novel prion protein conformation and glycotype in Creutzfeldt-Jakob disease. Archives of Neurology. 64: 595-9. PMID 17420324 DOI: 10.1001/Archneur.64.4.595  0.4
2007 Rostagno A, Lashley T, Ng D, Meyerson J, Braendgaard H, Plant G, Bojsen-Møller M, Holton J, Frangione B, Revesz T, Ghiso J. Preferential association of serum amyloid P component with fibrillar deposits in familial British and Danish dementias: similarities with Alzheimer's disease. Journal of the Neurological Sciences. 257: 88-96. PMID 17374542 DOI: 10.1016/J.Jns.2007.01.050  0.487
2006 Asuni AA, Boutajangout A, Scholtzova H, Knudsen E, Li YS, Quartermain D, Frangione B, Wisniewski T, Sigurdsson EM. Vaccination of Alzheimer's model mice with Abeta derivative in alum adjuvant reduces Abeta burden without microhemorrhages. The European Journal of Neuroscience. 24: 2530-42. PMID 17100841 DOI: 10.1111/J.1460-9568.2006.05149.X  0.41
2006 Leal MC, Dorfman VB, Gamba AF, Frangione B, Wisniewski T, Castaño EM, Sigurdsson EM, Morelli L. Plaque-associated overexpression of insulin-degrading enzyme in the cerebral cortex of aged transgenic tg2576 mice with Alzheimer pathology. Journal of Neuropathology and Experimental Neurology. 65: 976-87. PMID 17021402 DOI: 10.1097/01.Jnen.0000235853.70092.Ba  0.432
2006 Lashley T, Holton JL, Verbeek MM, Rostagno A, Bojsen-Møller M, David G, van Horssen J, Braendgaard H, Plant G, Frangione B, Ghiso J, Revesz T. Molecular chaperons, amyloid and preamyloid lesions in the BRI2 gene-related dementias: a morphological study. Neuropathology and Applied Neurobiology. 32: 492-504. PMID 16972883 DOI: 10.1111/J.1365-2990.2006.00747.X  0.441
2006 Levy E, Prelli F, Frangione B. Studies on the first described Alzheimer's disease amyloid beta mutant, the Dutch variant. Journal of Alzheimer's Disease : Jad. 9: 329-39. PMID 16914871 DOI: 10.3233/Jad-2006-9S337  0.494
2006 Ghiso J, Rostagno A, Tomidokoro Y, Lashley T, Bojsen-Møller M, Braendgaard H, Plant G, Holton J, Lal R, Revesz T, Frangione B. Genetic alterations of the BRI2 gene: familial British and Danish dementias. Brain Pathology (Zurich, Switzerland). 16: 71-9. PMID 16612984 DOI: 10.1111/J.1750-3639.2006.Tb00563.X  0.359
2006 Trouche S, Asuni A, Wisniewski T, Frangione B, Sigurdsson E, Verdier J, Mestre-Frances N. P4-290: Immunization with Aβ derivatives in Microcebus murinus : A primate lemurian model of Alzheimer's disease Alzheimer's & Dementia. 2: S602-S602. DOI: 10.1016/J.Jalz.2006.05.2029  0.354
2006 Ghiso JA, Quist A, Doudevski I, Lin H, Azimova R, Ng D, Frangione B, Kagan B, Lal R. P4-083 : Amyloid ion channels: A common structural link for protein-misfolding disease pathogenesis? Alzheimers & Dementia. 2. DOI: 10.1016/J.Jalz.2006.05.1821  0.345
2006 Cam JA, Meyerson JL, Ng D, Frangione B, Ghiso J, Rostagno A. P4-060: Oligomeric assemblies of the Aβ Dutch mutant induce the formation of nucleosomes in primary human cerebral endothelial cells Alzheimer's & Dementia. 2: S531-S531. DOI: 10.1016/J.Jalz.2006.05.1798  0.314
2006 Ghiso JA, Tomidokoro Y, Lashley T, Holton J, Revesz T, Rostagno A, Frangione B. P3-354: Post-translational modifications in Aβ and non-Aβ cerebral amyloidosis Alzheimer's & Dementia. 2: S479-S479. DOI: 10.1016/J.Jalz.2006.05.1624  0.369
2006 Tsachaki M, Fotinopoulou A, Vlavaki M, Poulopoulos A, Rostagno A, Frangione B, Ghiso J, Efthimiopoulos S. O2-03-06: BRI2 modulates amyloid precursor protein processing and inhibits aβ generation Alzheimer's & Dementia. 2: S36-S36. DOI: 10.1016/J.Jalz.2006.05.125  0.365
2005 Rábano A, Jiménez-Huete A, Acevedo B, Calero M, Ghiso J, Valdés I, Gavilondo J, Frangione B, Méndez E. Diversity of senile plaques in Alzheimer's disease as revealed by a new monoclonal antibody that recognizes an internal sequence of the Abeta peptide. Current Alzheimer Research. 2: 409-17. PMID 16248846 DOI: 10.2174/156720505774330500  0.455
2005 Tomidokoro Y, Lashley T, Rostagno A, Neubert TA, Bojsen-Møller M, Braendgaard H, Plant G, Holton J, Frangione B, Révész T, Ghiso J. Familial Danish dementia: co-existence of Danish and Alzheimer amyloid subunits (ADan AND A{beta}) in the absence of compact plaques. The Journal of Biological Chemistry. 280: 36883-94. PMID 16091362 DOI: 10.1074/Jbc.M504038200  0.446
2005 Westermark P, Benson MD, Buxbaum JN, Cohen AS, Frangione B, Ikeda S, Masters CL, Merlini G, Saraiva MJ, Sipe JD. Amyloid: toward terminology clarification. Report from the Nomenclature Committee of the International Society of Amyloidosis. Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis. 12: 1-4. PMID 16076605 DOI: 10.1080/13506120500032196  0.438
2005 Fotinopoulou A, Tsachaki M, Vlavaki M, Poulopoulos A, Rostagno A, Frangione B, Ghiso J, Efthimiopoulos S. BRI2 interacts with amyloid precursor protein (APP) and regulates amyloid beta (Abeta) production. The Journal of Biological Chemistry. 280: 30768-72. PMID 16027166 DOI: 10.1074/Jbc.C500231200  0.464
2005 Quist A, Doudevski I, Lin H, Azimova R, Ng D, Frangione B, Kagan B, Ghiso J, Lal R. Amyloid ion channels: a common structural link for protein-misfolding disease. Proceedings of the National Academy of Sciences of the United States of America. 102: 10427-32. PMID 16020533 DOI: 10.1073/Pnas.0502066102  0.412
2005 Matsuda S, Giliberto L, Matsuda Y, Davies P, McGowan E, Pickford F, Ghiso J, Frangione B, D'Adamio L. The familial dementia BRI2 gene binds the Alzheimer gene amyloid-beta precursor protein and inhibits amyloid-beta production. The Journal of Biological Chemistry. 280: 28912-6. PMID 15983050 DOI: 10.1074/Jbc.C500217200  0.386
2005 Prelli F, Pawlik M, Frangione B, Levy E. Purification of human wild-type or variant cystatin C from conditioned media of transfected cells. Methods in Molecular Biology (Clifton, N.J.). 299: 221-6. PMID 15980605 DOI: 10.1385/1-59259-874-9:221  0.353
2005 Rostagno A, Tomidokoro Y, Lashley T, Ng D, Plant G, Holton J, Frangione B, Revesz T, Ghiso J. Chromosome 13 dementias. Cellular and Molecular Life Sciences : Cmls. 62: 1814-25. PMID 15968464 DOI: 10.1007/S00018-005-5092-5  0.485
2005 Morelli L, Llovera RE, Alonso LG, Frangione B, de Prat-Gay G, Ghiso J, Castaño EM. Insulin-degrading enzyme degrades amyloid peptides associated with British and Danish familial dementia. Biochemical and Biophysical Research Communications. 332: 808-16. PMID 15913558 DOI: 10.1016/J.Bbrc.2005.05.020  0.42
2005 Wisniewski T, Frangione B. Immunological and anti-chaperone therapeutic approaches for Alzheimer disease. Brain Pathology (Zurich, Switzerland). 15: 72-7. PMID 15779239 DOI: 10.1111/J.1750-3639.2005.Tb00102.X  0.41
2005 Calero M, Rostagno A, Frangione B, Ghiso J. Clusterin and Alzheimer's disease. Sub-Cellular Biochemistry. 38: 273-98. PMID 15709484  0.349
2005 Calero M, Rostagno A, Frangione B, Ghiso J. Clusterin and Alzheimer’s Disease Sub-Cellular Biochemistry. 38: 273-298. DOI: 10.1007/0-387-23226-5_14  0.438
2004 Morelli L, Llovera RE, Mathov I, Lue LF, Frangione B, Ghiso J, Castaño EM. Insulin-degrading enzyme in brain microvessels: proteolysis of amyloid {beta} vasculotropic variants and reduced activity in cerebral amyloid angiopathy. The Journal of Biological Chemistry. 279: 56004-13. PMID 15489232 DOI: 10.1074/Jbc.M407283200  0.461
2004 Ghiso J, Shayo M, Calero M, Ng D, Tomidokoro Y, Gandy S, Rostagno A, Frangione B. Systemic catabolism of Alzheimer's Abeta40 and Abeta42. The Journal of Biological Chemistry. 279: 45897-908. PMID 15322125 DOI: 10.1074/Jbc.M407668200  0.42
2004 Sigurdsson EM, Knudsen E, Asuni A, Fitzer-Attas C, Sage D, Quartermain D, Goni F, Frangione B, Wisniewski T. An attenuated immune response is sufficient to enhance cognition in an Alzheimer's disease mouse model immunized with amyloid-beta derivatives. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 6277-82. PMID 15254082 DOI: 10.1523/Jneurosci.1344-04.2004  0.407
2004 Zanusso G, Farinazzo A, Prelli F, Fiorini M, Gelati M, Ferrari S, Righetti PG, Rizzuto N, Frangione B, Monaco S. Identification of distinct N-terminal truncated forms of prion protein in different Creutzfeldt-Jakob disease subtypes. The Journal of Biological Chemistry. 279: 38936-42. PMID 15247220 DOI: 10.1074/Jbc.M405468200  0.394
2004 Matsubara E, Sekijima Y, Tokuda T, Urakami K, Amari M, Shizuka-Ikeda M, Tomidokoro Y, Ikeda M, Kawarabayashi T, Harigaya Y, Ikeda S, Murakami T, Abe K, Otomo E, Hirai S, ... Frangione B, et al. Soluble Abeta homeostasis in AD and DS: impairment of anti-amyloidogenic protection by lipoproteins. Neurobiology of Aging. 25: 833-41. PMID 15212837 DOI: 10.1016/J.Neurobiolaging.2003.10.004  0.398
2004 Sastre M, Calero M, Pawlik M, Mathews PM, Kumar A, Danilov V, Schmidt SD, Nixon RA, Frangione B, Levy E. Binding of cystatin C to Alzheimer's amyloid beta inhibits in vitro amyloid fibril formation. Neurobiology of Aging. 25: 1033-43. PMID 15212828 DOI: 10.1016/J.Neurobiolaging.2003.11.006  0.424
2004 Choi SI, Vidal R, Frangione B, Levy E. Axonal transport of British and Danish amyloid peptides via secretory vesicles. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 18: 373-5. PMID 14656991 DOI: 10.1096/Fj.03-0730Fje  0.375
2004 Lashley T, Holton JL, Frangione B, Bandopadhyay R, Ghiso J, Rostagno A, Revesz T. P1-264 The possible origin of the amyloid peptides in the BRI2 gene-related dementias Neurobiology of Aging. 25: S171. DOI: 10.1016/S0197-4580(04)80577-3  0.379
2004 Rostagno A, Zhao Z, Ng D, Lashley T, Holton J, Frangione B, Revesz T, Ghiso J. P1-262 Familial British and Danish dementias: BRI2 gene and protein expression by human cerebral cells Neurobiology of Aging. 25. DOI: 10.1016/S0197-4580(04)80575-X  0.303
2004 Morelli L, Llovera RE, Frangione B, Ghiso J, Castaño EM. P1-177 Insulin degrading enzyme from human brain microvessels degrades amyloid β and its flemish, Dutch and Italian vasculotropic variants Neurobiology of Aging. 25: S146. DOI: 10.1016/S0197-4580(04)80490-1  0.306
2004 Tomidokoro Y, Rostagno A, Greenberg SM, Frangione B, Rebeck WG, Ghiso J. O2-03-07 Biochemical analysis of Aβ amyloid deposits in the Iowa variant of Alzheimer's disease Neurobiology of Aging. 25: S38. DOI: 10.1016/S0197-4580(04)80125-8  0.417
2004 Wisniewski T, Pankiewicz J, Scholtzova H, Fernando G, Chabalgoity JA, Ji Y, Wadghiri YZ, Gan W, Tang CY, Turnbull DH, Mathis CA, Kascsak R, Klunk WE, Carp RI, Frangione B, et al. S2-04-04 Imaging and therapeutic approaches for β-sheet structures in prion and Alzheimer's diseases Neurobiology of Aging. 25. DOI: 10.1016/S0197-4580(04)80100-3  0.318
2003 Berasain P, Carmona C, Frangione B, Cazzulo JJ, Goñi F. Specific cleavage sites on human IgG subclasses by cruzipain, the major cysteine proteinase from Trypanosoma cruzi. Molecular and Biochemical Parasitology. 130: 23-9. PMID 14550893 DOI: 10.1016/S0166-6851(03)00139-7  0.301
2003 Revesz T, Ghiso J, Lashley T, Plant G, Rostagno A, Frangione B, Holton JL. Cerebral amyloid angiopathies: a pathologic, biochemical, and genetic view. Journal of Neuropathology and Experimental Neurology. 62: 885-98. PMID 14533778 DOI: 10.1093/Jnen/62.9.885  0.461
2003 Deane R, Du Yan S, Submamaryan RK, LaRue B, Jovanovic S, Hogg E, Welch D, Manness L, Lin C, Yu J, Zhu H, Ghiso J, Frangione B, Stern A, Schmidt AM, et al. RAGE mediates amyloid-beta peptide transport across the blood-brain barrier and accumulation in brain. Nature Medicine. 9: 907-13. PMID 12808450 DOI: 10.1038/Nm890  0.396
2003 Morelli L, Llovera R, Gonzalez SA, Affranchino JL, Prelli F, Frangione B, Ghiso J, Castano EM. Differential degradation of amyloid beta genetic variants associated with hereditary dementia or stroke by insulin-degrading enzyme. The Journal of Biological Chemistry. 278: 23221-6. PMID 12695513 DOI: 10.1074/Jbc.M300276200  0.442
2003 Sigurdsson EM, Sy MS, Li R, Scholtzova H, Kascsak RJ, Kascsak R, Carp R, Meeker HC, Frangione B, Wisniewski T. Anti-prion antibodies for prophylaxis following prion exposure in mice. Neuroscience Letters. 336: 185-7. PMID 12505623 DOI: 10.1016/S0304-3940(02)01192-8  0.331
2002 Matsubara E, Shoji M, Abe K, Frangione B, Ghiso J. Vascular Amyloidosis in Neurodegenerative Conditions. Drug News & Perspectives. 15: 439-444. PMID 12677179 DOI: 10.1358/Dnp.2002.15.7.840079  0.41
2002 Mackic JB, Bading J, Ghiso J, Walker L, Wisniewski T, Frangione B, Zlokovic BV. Circulating amyloid-beta peptide crosses the blood-brain barrier in aged monkeys and contributes to Alzheimer's disease lesions. Vascular Pharmacology. 38: 303-13. PMID 12529925 DOI: 10.1016/S1537-1891(02)00198-2  0.349
2002 Sigurdsson EM, Wisniewski T, Frangione B. A safer vaccine for Alzheimer's disease? Neurobiology of Aging. 23: 1001-8. PMID 12470795 DOI: 10.1016/S0197-4580(02)00124-0  0.399
2002 Ghiso J, Frangione B. Amyloidosis and Alzheimer's disease. Advanced Drug Delivery Reviews. 54: 1539-51. PMID 12453671 DOI: 10.1016/S0169-409X(02)00149-7  0.45
2002 Westermark P, Benson MD, Buxbaum JN, Cohen AS, Frangione B, Ikeda S, Masters CL, Merlini G, Saraiva MJ, Sipe JD. Amyloid fibril protein nomenclature -- 2002. Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis. 9: 197-200. PMID 12408684  0.306
2002 Rostagno A, Revesz T, Lashley T, Tomidokoro Y, Magnotti L, Braendgaard H, Plant G, Bojsen-Møller M, Holton J, Frangione B, Ghiso J. Complement activation in chromosome 13 dementias. Similarities with Alzheimer's disease. The Journal of Biological Chemistry. 277: 49782-90. PMID 12388551 DOI: 10.1074/Jbc.M206448200  0.425
2002 Sigurdsson EM, Wisniewski T, Frangione B. Infectivity of amyloid diseases. Trends in Molecular Medicine. 8: 411-3. PMID 12223307 DOI: 10.1016/S1471-4914(02)02403-6  0.459
2002 Bading JR, Yamada S, Mackic JB, Kirkman L, Miller C, Calero M, Ghiso J, Frangione B, Zlokovic BV. Brain clearance of Alzheimer's amyloid-beta40 in the squirrel monkey: a SPECT study in a primate model of cerebral amyloid angiopathy. Journal of Drug Targeting. 10: 359-68. PMID 12164385 DOI: 10.1080/10611860290031831  0.393
2002 Revesz T, Holton JL, Lashley T, Plant G, Rostagno A, Ghiso J, Frangione B. Sporadic and familial cerebral amyloid angiopathies. Brain Pathology (Zurich, Switzerland). 12: 343-57. PMID 12146803 DOI: 10.1111/J.1750-3639.2002.Tb00449.X  0.426
2002 Sigurdsson EM, Brown DR, Daniels M, Kascsak RJ, Kascsak R, Carp R, Meeker HC, Frangione B, Wisniewski T. Immunization delays the onset of prion disease in mice. The American Journal of Pathology. 161: 13-7. PMID 12107084 DOI: 10.1016/S0002-9440(10)64151-X  0.314
2002 Holton JL, Lashley T, Ghiso J, Braendgaard H, Vidal R, Guerin CJ, Gibb G, Hanger DP, Rostagno A, Anderton BH, Strand C, Ayling H, Plant G, Frangione B, Bojsen-Møller M, et al. Familial Danish dementia: a novel form of cerebral amyloidosis associated with deposition of both amyloid-Dan and amyloid-beta. Journal of Neuropathology and Experimental Neurology. 61: 254-67. PMID 11895040 DOI: 10.1093/Jnen/61.3.254  0.456
2002 Holton JL, Ghiso J, Lashley T, Ganguly M, Strand K, Rostagno A, Plant G, Frangione B, Revesz T. Familial British dementia (FBD): a cerebral amyloidosis with systemic amyloid deposition Neuropathology and Applied Neurobiology. 28: 148-148. DOI: 10.1046/J.1365-2990.2002.39286_2.X  0.394
2001 Wisniewski T, Sigurdsson EM, Aucouturier P, Frangione B. Conformation as therapeutic target in the prionoses and other neurodegenerative conditions. Methods in Molecular Medicine. 59: 223-36. PMID 21374507 DOI: 10.1385/1-59259-134-5:223  0.438
2001 Ghiso J, Frangione B. Cerebral amyloidosis, amyloid angiopathy, and their relationship to stroke and dementia. Journal of Alzheimer's Disease : Jad. 3: 65-73. PMID 12214074 DOI: 10.3233/Jad-2001-3110  0.399
2001 Ghiso J, Révész T, Holton J, Rostagno A, Lashley T, Houlden H, Gibb G, Anderton B, Bek T, Bojsen-Møller M, Wood N, Vidal R, Braendgaard H, Plant G, Frangione B. Chromosome 13 dementia syndromes as models of neurodegeneration. Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis. 8: 277-84. PMID 11791622 DOI: 10.3109/13506120108993826  0.376
2001 Poeggeler B, Miravalle L, Zagorski MG, Wisniewski T, Chyan YJ, Zhang Y, Shao H, Bryant-Thomas T, Vidal R, Frangione B, Ghiso J, Pappolla MA. Melatonin reverses the profibrillogenic activity of apolipoprotein E4 on the Alzheimer amyloid Abeta peptide. Biochemistry. 40: 14995-5001. PMID 11732920 DOI: 10.1021/Bi0114269  0.674
2001 Ghiso JA, Holton J, Miravalle L, Calero M, Lashley T, Vidal R, Houlden H, Wood N, Neubert TA, Rostagno A, Plant G, Revesz T, Frangione B. Systemic amyloid deposits in familial British dementia. The Journal of Biological Chemistry. 276: 43909-14. PMID 11557758 DOI: 10.1074/Jbc.M105956200  0.487
2001 Sigurdsson EM, Scholtzova H, Mehta PD, Frangione B, Wisniewski T. Immunization with a nontoxic/nonfibrillar amyloid-beta homologous peptide reduces Alzheimer's disease-associated pathology in transgenic mice. The American Journal of Pathology. 159: 439-47. PMID 11485902 DOI: 10.1016/S0002-9440(10)61715-4  0.409
2001 Calero M, Pawlik M, Soto C, Castaño EM, Sigurdsson EM, Kumar A, Gallo G, Frangione B, Levy E. Distinct properties of wild-type and the amyloidogenic human cystatin C variant of hereditary cerebral hemorrhage with amyloidosis, Icelandic type. Journal of Neurochemistry. 77: 628-37. PMID 11299325 DOI: 10.1046/J.1471-4159.2001.00256.X  0.343
2001 Vidal R, Calero M, Révész T, Plant G, Ghiso J, Frangione B. Sequence, genomic structure and tissue expression of Human BRI3, a member of the BRI gene family. Gene. 266: 95-102. PMID 11290423 DOI: 10.1016/S0378-1119(01)00374-2  0.32
2001 Holton JL, Ghiso J, Lashley T, Rostagno A, Guerin CJ, Gibb G, Houlden H, Ayling H, Martinian L, Anderton BH, Wood NW, Vidal R, Plant G, Frangione B, Revesz T. Regional distribution of amyloid-Bri deposition and its association with neurofibrillary degeneration in familial British dementia. The American Journal of Pathology. 158: 515-26. PMID 11159188 DOI: 10.1016/S0002-9440(10)63993-4  0.415
2001 Tagliavini F, Lievens PM, Tranchant C, Warter JM, Mohr M, Giaccone G, Perini F, Rossi G, Salmona M, Piccardo P, Ghetti B, Beavis RC, Bugiani O, Frangione B, Prelli F. A 7-kDa prion protein (PrP) fragment, an integral component of the PrP region required for infectivity, is the major amyloid protein in Gerstmann-Sträussler-Scheinker disease A117V. The Journal of Biological Chemistry. 276: 6009-15. PMID 11087738 DOI: 10.1074/Jbc.M007062200  0.441
2000 Ghiso J, Vidal R, Rostagno A, Miravalle L, Holton JL, Mead S, Révész T, Plant G, Frangione B. Amyloidogenesis in familial British dementia is associated with a genetic defect on chromosome 13. Annals of the New York Academy of Sciences. 920: 84-92. PMID 11193180 DOI: 10.1111/J.1749-6632.2000.Tb06908.X  0.375
2000 Vidal R, Ghiso J, Frangione B. New familial forms of cerebral amyloid and dementia. Molecular Psychiatry. 5: 575-6. PMID 11126387 DOI: 10.1038/Sj.Mp.4000797  0.358
2000 Shibata M, Yamada S, Kumar SR, Calero M, Bading J, Frangione B, Holtzman DM, Miller CA, Strickland DK, Ghiso J, Zlokovic BV. Clearance of Alzheimer's amyloid-ss(1-40) peptide from brain by LDL receptor-related protein-1 at the blood-brain barrier. The Journal of Clinical Investigation. 106: 1489-99. PMID 11120756 DOI: 10.1172/Jci10498  0.364
2000 Calero M, Rostagno A, Matsubara E, Zlokovic B, Frangione B, Ghiso J. Apolipoprotein J (clusterin) and Alzheimer's disease. Microscopy Research and Technique. 50: 305-15. PMID 10936885 DOI: 10.1002/1097-0029(20000815)50:4<305::Aid-Jemt10>3.0.Co;2-L  0.449
2000 Vidal R, Calero M, Piccardo P, Farlow MR, Unverzagt FW, Méndez E, Jiménez-Huete A, Beavis R, Gallo G, Gomez-Tortosa E, Ghiso J, Hyman BT, Frangione B, Ghetti B. Senile dementia associated with amyloid beta protein angiopathy and tau perivascular pathology but not neuritic plaques in patients homozygous for the APOE-epsilon4 allele. Acta Neuropathologica. 100: 1-12. PMID 10912914 DOI: 10.1007/S004010051186  0.496
2000 Zlokovic BV, Yamada S, Holtzman D, Ghiso J, Frangione B. Clearance of amyloid beta-peptide from brain: transport or metabolism? Nature Medicine. 6: 718. PMID 10888893 DOI: 10.1038/77397  0.37
2000 Frangione B, Vidal R, Rostagno A, Ghiso J. Familial cerebral amyloid angiopathies and dementia. Alzheimer Disease and Associated Disorders. 14: S25-30. PMID 10850727 DOI: 10.1097/00002093-200000001-00005  0.481
2000 Pappolla MA, Chyan YJ, Poeggeler B, Frangione B, Wilson G, Ghiso J, Reiter RJ. An assessment of the antioxidant and the antiamyloidogenic properties of melatonin: implications for Alzheimer's disease. Journal of Neural Transmission (Vienna, Austria : 1996). 107: 203-31. PMID 10847561 DOI: 10.1007/S007020050018  0.581
2000 Miravalle L, Tokuda T, Chiarle R, Giaccone G, Bugiani O, Tagliavini F, Frangione B, Ghiso J. Substitutions at codon 22 of Alzheimer's abeta peptide induce diverse conformational changes and apoptotic effects in human cerebral endothelial cells. The Journal of Biological Chemistry. 275: 27110-6. PMID 10821838 DOI: 10.1074/Jbc.M003154200  0.47
2000 Ghiso J, Vidal R, Rostagno A, Mead S, Révész T, Plant G, Frangione B. A newly formed amyloidogenic fragment due to a stop codon mutation causes familial British dementia. Annals of the New York Academy of Sciences. 903: 129-37. PMID 10818498 DOI: 10.1111/J.1749-6632.2000.Tb06359.X  0.356
2000 Tokuda T, Calero M, Matsubara E, Vidal R, Kumar A, Permanne B, Zlokovic B, Smith JD, Ladu MJ, Rostagno A, Frangione B, Ghiso J. Lipidation of apolipoprotein E influences its isoform-specific interaction with Alzheimer's amyloid beta peptides. The Biochemical Journal. 348: 359-65. PMID 10816430 DOI: 10.1042/0264-6021:3480359  0.436
2000 Vidal R, Revesz T, Rostagno A, Kim E, Holton JL, Bek T, Bojsen-Møller M, Braendgaard H, Plant G, Ghiso J, Frangione B. A decamer duplication in the 3' region of the BRI gene originates an amyloid peptide that is associated with dementia in a Danish kindred. Proceedings of the National Academy of Sciences of the United States of America. 97: 4920-5. PMID 10781099 DOI: 10.1073/Pnas.080076097  0.46
2000 Mead S, James-Galton M, Revesz T, Doshi RB, Harwood G, Pan EL, Ghiso J, Frangione B, Plant G. Familial British dementia with amyloid angiopathy: early clinical, neuropsychological and imaging findings. Brain : a Journal of Neurology. 123: 975-91. PMID 10775542 DOI: 10.1093/Brain/123.5.975  0.327
2000 Strazielle N, Ghersi-Egea JF, Ghiso J, Dehouck MP, Frangione B, Patlak C, Fenstermacher J, Gorevic P. In vitro evidence that beta-amyloid peptide 1-40 diffuses across the blood-brain barrier and affects its permeability. Journal of Neuropathology and Experimental Neurology. 59: 29-38. PMID 10744033 DOI: 10.1093/Jnen/59.1.29  0.429
2000 Sigurdsson EM, Permanne B, Soto C, Wisniewski T, Frangione B. In vivo reversal of amyloid-beta lesions in rat brain. Journal of Neuropathology and Experimental Neurology. 59: 11-7. PMID 10744031 DOI: 10.1093/Jnen/59.1.11  0.447
2000 Soto C, Kascsak RJ, Saborío GP, Aucouturier P, Wisniewski T, Prelli F, Kascsak R, Mendez E, Harris DA, Ironside J, Tagliavini F, Carp RI, Frangione B. Reversion of prion protein conformational changes by synthetic beta-sheet breaker peptides. Lancet. 355: 192-7. PMID 10675119 DOI: 10.1016/S0140-6736(99)11419-3  0.377
2000 Berasain P, Carmona C, Frangione B, Dalton JP, Goñi F. Fasciola hepatica: parasite-secreted proteinases degrade all human IgG subclasses: determination of the specific cleavage sites and identification of the immunoglobulin fragments produced. Experimental Parasitology. 94: 99-110. PMID 10673346 DOI: 10.1006/Expr.1999.4479  0.313
2000 Vidal RG, Calero M, Ghiso J, Frangione B. BRI amyloid precursor protein isoforms. BRI2 is mutated in familial British dementia Neurobiology of Aging. 21: 13. DOI: 10.1016/S0197-4580(00)82737-2  0.375
2000 Miravalle L, Vidal RG, Calero M, Révész T, Plant G, Frangione B, Ghiso J. N-terminal pyroglutamate enhances the fibrillogenic properties of the ABRI peptide in familial British dementia Neurobiology of Aging. 21: 84. DOI: 10.1016/S0197-4580(00)82600-7  0.313
2000 Vidal RG, Révész T, Rostagno A, Bek T, Braendgaard H, Plant G, Ghiso J, Frangione B. A decamer duplication in the BRI gene originates a de-novo amyloid peptide that causes dementia in a Danish kindred Neurobiology of Aging. 21: 58. DOI: 10.1016/S0197-4580(00)82484-7  0.387
2000 Révész T, Holton JL, Vidal RG, Rostagno A, Lashley T, Plant G, Frangione B, Ghiso J. Cerebral deposition of ABRI amyloid in familial British dementia Neurobiology of Aging. 21: 191. DOI: 10.1016/S0197-4580(00)82203-4  0.376
1999 Rostagno A, Vidal R, Kaplan B, Chuba J, Kumar A, Elliott JI, Frangione B, Gallo G, Ghiso J. pH-dependent fibrillogenesis of a VkappaIII Bence Jones protein. British Journal of Haematology. 107: 835-43. PMID 10606892 DOI: 10.1046/J.1365-2141.1999.01778.X  0.371
1999 Vidal R, Goñi F, Stevens F, Aucouturier P, Kumar A, Frangione B, Ghiso J, Gallo G. Somatic mutations of the L12a gene in V-kappa(1) light chain deposition disease: potential effects on aberrant protein conformation and deposition. The American Journal of Pathology. 155: 2009-17. PMID 10595931 DOI: 10.1016/S0002-9440(10)65520-4  0.374
1999 Calero M, Tokuda T, Rostagno A, Kumar A, Zlokovic B, Frangione B, Ghiso J. Functional and structural properties of lipid-associated apolipoprotein J (clusterin). The Biochemical Journal. 344: 375-83. PMID 10567218 DOI: 10.1042/Bj3440375  0.307
1999 Aucouturier P, Kascsak RJ, Frangione B, Wisniewski T. Biochemical and conformational variability of human prion strains in sporadic Creutzfeldt-Jakob disease. Neuroscience Letters. 274: 33-6. PMID 10530513 DOI: 10.1016/S0304-3940(99)00659-X  0.331
1999 Chyan YJ, Poeggeler B, Omar RA, Chain DG, Frangione B, Ghiso J, Pappolla MA. Potent neuroprotective properties against the Alzheimer beta-amyloid by an endogenous melatonin-related indole structure, indole-3-propionic acid. The Journal of Biological Chemistry. 274: 21937-42. PMID 10419516 DOI: 10.1074/Jbc.274.31.21937  0.643
1999 Vidal R, Frangione B, Rostagno A, Mead S, Révész T, Plant G, Ghiso J. A stop-codon mutation in the BRI gene associated with familial British dementia. Nature. 399: 776-81. PMID 10391242 DOI: 10.1038/21637  0.453
1999 Poduslo JF, Curran GL, Kumar A, Frangione B, Soto C. Beta-sheet breaker peptide inhibitor of Alzheimer's amyloidogenesis with increased blood-brain barrier permeability and resistance to proteolytic degradation in plasma. Journal of Neurobiology. 39: 371-82. PMID 10363910 DOI: 10.1002/(Sici)1097-4695(19990605)39:3<371::Aid-Neu4>3.0.Co;2-E  0.402
1999 Saborío GP, Soto C, Kascsak RJ, Levy E, Kascsak R, Harris DA, Frangione B. Cell-lysate conversion of prion protein into its protease-resistant isoform suggests the participation of a cellular chaperone. Biochemical and Biophysical Research Communications. 258: 470-5. PMID 10329411 DOI: 10.1006/Bbrc.1999.0660  0.31
1999 Matsubara E, Ghiso J, Frangione B, Amari M, Tomidokoro Y, Ikeda Y, Harigaya Y, Okamoto K, Shoji M. Lipoprotein-free amyloidogenic peptides in plasma are elevated in patients with sporadic Alzheimer's disease and Down's syndrome. Annals of Neurology. 45: 537-41. PMID 10211483 DOI: 10.1002/1531-8249(199904)45:4<537::Aid-Ana20>3.0.Co;2-2  0.345
1998 Wisniewski T, Aucouturier P, Soto C, Frangione B. The prionoses and other conformational disorders. Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis. 5: 212-24. PMID 9818059 DOI: 10.3109/13506129809003848  0.479
1998 Jiménez-Huete A, Lievens PM, Vidal R, Piccardo P, Ghetti B, Tagliavini F, Frangione B, Prelli F. Endogenous proteolytic cleavage of normal and disease-associated isoforms of the human prion protein in neural and non-neural tissues. The American Journal of Pathology. 153: 1561-72. PMID 9811348 DOI: 10.1016/S0002-9440(10)65744-6  0.355
1998 Crawford F, Soto C, Suo Z, Fang C, Parker T, Sawar A, Frangione B, Mullan M. Alzheimer's beta-amyloid vasoactivity: identification of a novel beta-amyloid conformational intermediate. Febs Letters. 436: 445-8. PMID 9801166 DOI: 10.1016/S0014-5793(98)01170-3  0.34
1998 Soto C, Sigurdsson EM, Morelli L, Kumar RA, Castaño EM, Frangione B. Beta-sheet breaker peptides inhibit fibrillogenesis in a rat brain model of amyloidosis: implications for Alzheimer's therapy. Nature Medicine. 4: 822-6. PMID 9662374 DOI: 10.1038/Nm0798-822  0.448
1998 Pappolla M, Bozner P, Soto C, Shao H, Robakis NK, Zagorski M, Frangione B, Ghiso J. Inhibition of Alzheimer beta-fibrillogenesis by melatonin. The Journal of Biological Chemistry. 273: 7185-8. PMID 9516407 DOI: 10.1074/Jbc.273.13.7185  0.667
1998 Mackic JB, Weiss MH, Miao W, Kirkman E, Ghiso J, Calero M, Bading J, Frangione B, Zlokovic BV. Cerebrovascular accumulation and increased blood-brain barrier permeability to circulating Alzheimer's amyloid beta peptide in aged squirrel monkey with cerebral amyloid angiopathy. Journal of Neurochemistry. 70: 210-5. PMID 9422364 DOI: 10.1046/J.1471-4159.1998.70010210.X  0.357
1997 Wisniewski T, Ghiso J, Frangione B. Biology of A beta amyloid in Alzheimer's disease. Neurobiology of Disease. 4: 313-28. PMID 9440120 DOI: 10.1006/Nbdi.1997.0147  0.398
1997 Kaplan B, Vidal R, Kumar A, Ghiso J, Frangione B, Gallo G. Amino-terminal identity of co-existent amyloid and non-amyloid immunoglobulin kappa light chain deposits. A human disease to study alterations of protein conformation. Clinical and Experimental Immunology. 110: 472-8. PMID 9409653 DOI: 10.1046/J.1365-2249.1997.4421454.X  0.345
1997 Permanne B, Perez C, Soto C, Frangione B, Wisniewski T. Detection of apolipoprotein E/dimeric soluble amyloid beta complexes in Alzheimer's disease brain supernatants. Biochemical and Biophysical Research Communications. 240: 715-20. PMID 9398632 DOI: 10.1006/Bbrc.1997.7727  0.453
1997 Wisniewski T, Dowjat WK, Permanne B, Palha J, Kumar A, Gallo G, Frangione B. Presenilin-1 is associated with Alzheimer's disease amyloid. The American Journal of Pathology. 151: 601-10. PMID 9250173  0.39
1997 Ghiso J, Calero M, Matsubara E, Governale S, Chuba J, Beavis R, Wisniewski T, Frangione B. Alzheimer's soluble amyloid beta is a normal component of human urine. Febs Letters. 408: 105-8. PMID 9180278 DOI: 10.1016/S0014-5793(97)00400-6  0.388
1997 Castaño EM, Prelli F, Morelli L, Avagnina A, Kahn A, Frangione B. Immunoglobulin lambda light chains are the precursors of ureteral localized amyloidosis: a micromethod for extraction of amyloid Amyloid. 4: 253-258. DOI: 10.3109/13506129709003836  0.426
1996 Rostagno A, Vidal R, Kumar A, Chuba J, Niederman G, Gold L, Frangione B, Ghiso J, Gallo G. Fibrillary glomerulonephritis related to serum fibrillar immunoglobulin-fibronectin complexes. American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation. 28: 676-84. PMID 9158204 DOI: 10.1016/S0272-6386(96)90248-6  0.397
1996 Lalowski M, Golabek A, Lemere CA, Selkoe DJ, Wisniewski HM, Beavis RC, Frangione B, Wisniewski T. The "nonamyloidogenic" p3 fragment (amyloid beta17-42) is a major constituent of Down's syndrome cerebellar preamyloid. The Journal of Biological Chemistry. 271: 33623-31. PMID 8969231 DOI: 10.1074/Jbc.271.52.33623  0.446
1996 Castaño EM, Prelli F, Soto C, Beavis R, Matsubara E, Shoji M, Frangione B. The length of amyloid-beta in hereditary cerebral hemorrhage with amyloidosis, Dutch type. Implications for the role of amyloid-beta 1-42 in Alzheimer's disease. The Journal of Biological Chemistry. 271: 32185-91. PMID 8943274 DOI: 10.1074/Jbc.271.50.32185  0.472
1996 Piccardo P, Seiler C, Dlouhy SR, Young K, Farlow MR, Prelli F, Frangione B, Bugiani O, Tagliavini F, Ghetti B. Proteinase-K-resistant prion protein isoforms in Gerstmann-Sträussler-Scheinker disease (Indiana kindred). Journal of Neuropathology and Experimental Neurology. 55: 1157-63. PMID 8939199 DOI: 10.1097/00005072-199611000-00007  0.376
1996 Palha JA, Moreira P, Wisniewski T, Frangione B, Saraiva MJ. Transthyretin gene in Alzheimer's disease patients. Neuroscience Letters. 204: 212-4. PMID 8938268 DOI: 10.1016/0304-3940(96)12334-X  0.454
1996 Frangione B, Castaño EM, Wisniewski T, Ghiso J, Prelli F, Vidal R. Apolipoprotein E and amyloidogenesis. Ciba Foundation Symposium. 199: 132-41; discussion 1. PMID 8915608 DOI: 10.1002/9780470514924.Ch9  0.414
1996 Soto C, Kindy MS, Baumann M, Frangione B. Inhibition of Alzheimer's amyloidosis by peptides that prevent beta-sheet conformation. Biochemical and Biophysical Research Communications. 226: 672-80. PMID 8831674 DOI: 10.1006/Bbrc.1996.1413  0.397
1996 Vidal R, Ghiso J, Wisniewski T, Frangione B. Alzheimer's presenilin 1 gene expression in platelets and megakaryocytes. Identification of a novel splice variant. Febs Letters. 393: 19-23. PMID 8804415 DOI: 10.1016/0014-5793(96)00845-9  0.349
1996 Ghersi-Egea JF, Gorevic PD, Ghiso J, Frangione B, Patlak CS, Fenstermacher JD. Fate of cerebrospinal fluid-borne amyloid beta-peptide: rapid clearance into blood and appreciable accumulation by cerebral arteries. Journal of Neurochemistry. 67: 880-3. PMID 8764620 DOI: 10.1046/J.1471-4159.1996.67020880.X  0.329
1996 Ghetti B, Piccardo P, Frangione B, Bugiani O, Giaccone G, Young K, Prelli F, Farlow MR, Dlouhy SR, Tagliavini F. Prion protein amyloidosis. Brain Pathology (Zurich, Switzerland). 6: 127-45. PMID 8737929 DOI: 10.1111/J.1750-3639.1996.Tb00796.X  0.326
1996 Perini F, Vidal R, Ghetti B, Tagliavini F, Frangione B, Prelli F. PrP27-30 is a normal soluble prion protein fragment released by human platelets. Biochemical and Biophysical Research Communications. 223: 572-7. PMID 8687437 DOI: 10.1006/Bbrc.1996.0936  0.354
1996 Matsubara E, Soto C, Governale S, Frangione B, Ghiso J. Apolipoprotein J and Alzheimer's amyloid beta solubility. The Biochemical Journal. 316: 671-9. PMID 8687416 DOI: 10.1042/Bj3160671  0.361
1996 Morelli L, Wei L, Amorim A, McDermid J, Abee CR, Frangione B, Walker LC, Levy E. Cerebrovascular amyloidosis in squirrel monkeys and rhesus monkeys: apolipoprotein E genotype. Febs Letters. 379: 132-4. PMID 8635577 DOI: 10.1016/0014-5793(95)01491-8  0.326
1996 Wisniewski T, Lalowski M, Bobik M, Russell M, Strosznajder J, Frangione B. Amyloid beta 1-42 deposits do not lead to Alzheimer's neuritic plaques in aged dogs. The Biochemical Journal. 313: 575-80. PMID 8573095 DOI: 10.1042/Bj3130575  0.401
1996 Ghetti B, Piccardo P, Spillantini MG, Ichimiya Y, Porro M, Perini F, Kitamoto T, Tateishi J, Seiler C, Frangione B, Bugiani O, Giaccone G, Prelli F, Goedert M, Dlouhy SR, et al. Vascular variant of prion protein cerebral amyloidosis with tau-positive neurofibrillary tangles: the phenotype of the stop codon 145 mutation in PRNP. Proceedings of the National Academy of Sciences of the United States of America. 93: 744-8. PMID 8570627 DOI: 10.1073/Pnas.93.2.744  0.454
1996 Giaccone G, Pedrotti B, Migheli A, Verga L, Perez J, Racagni G, Smith MA, Perry G, De Gioia L, Selvaggini C, Salmona M, Ghiso J, Frangione B, Islam K, Bugiani O, et al. beta PP and Tau interaction. A possible link between amyloid and neurofibrillary tangles in Alzheimer's disease. The American Journal of Pathology. 148: 79-87. PMID 8546229  0.338
1996 Soto C, Kindy MS, Prelli F, de Beer FC, Frangione B. 581 Inhibiting amyloid formation by peptides with anti-β-sheet conformation: A novel therapeutic approach for alzheimer's disease Neurobiology of Aging. 17: S145. DOI: 10.1016/S0197-4580(96)80583-5  0.412
1996 Ghetti B, Piccardo P, Frangione B, Bugiani O, Giaccone G, Young K, Prelli F, Farlow MR, Dlouhy SR, Tagliavini F. Prion protein hereditary amyloidosis: Parenchymal and vascular Seminars in Virology. 7: 189-200. DOI: 10.1006/Smvy.1996.0024  0.442
1995 Soto C, Castaño EM, Kumar RA, Beavis RC, Frangione B. Fibrillogenesis of synthetic amyloid-beta peptides is dependent on their initial secondary structure. Neuroscience Letters. 200: 105-8. PMID 8614555 DOI: 10.1016/0304-3940(95)12089-M  0.443
1995 Levy E, Amorim A, Frangione B, Walker LC. beta-Amyloid precursor protein gene in squirrel monkeys with cerebral amyloid angiopathy. Neurobiology of Aging. 16: 805-8. PMID 8532114 DOI: 10.1016/0197-4580(95)00090-2  0.425
1995 Wisniewski T, Morelli L, Wegiel J, Levy E, Wisniewski HM, Frangione B. The influence of apolipoprotein E isotypes on Alzheimer's disease pathology in 40 cases of Down's syndrome. Annals of Neurology. 37: 136-8. PMID 7818249 DOI: 10.1002/Ana.410370128  0.31
1995 Soto C, Frangione B. Two conformational states of amyloid beta-peptide: implications for the pathogenesis of Alzheimer's disease. Neuroscience Letters. 186: 115-8. PMID 7777177 DOI: 10.1016/0304-3940(95)11299-C  0.407
1995 Ghetti B, Dlouhy SR, Giaccone G, Bugiani O, Frangione B, Farlow MR, Tagliavini F. Gerstmann-Sträussler-Scheinker disease and the Indiana kindred. Brain Pathology (Zurich, Switzerland). 5: 61-75. PMID 7767492 DOI: 10.1111/J.1750-3639.1995.Tb00578.X  0.358
1995 Ghiso J, Plant GT, Révész T, Wisniewski T, Frangione B. Familial cerebral amyloid angiopathy (British type) with nonneuritic amyloid plaque formation may be due to a novel amyloid protein. Journal of the Neurological Sciences. 129: 74-5. PMID 7751849 DOI: 10.1016/0022-510X(94)00274-R  0.453
1995 Matsubara E, Frangione B, Ghiso J. Characterization of apolipoprotein J-Alzheimer's A beta interaction. The Journal of Biological Chemistry. 270: 7563-7. PMID 7706304 DOI: 10.1074/Jbc.270.13.7563  0.439
1995 Wisniewski T, Golabek AA, Kida E, Wisniewski KE, Frangione B. Conformational mimicry in Alzheimer's disease. Role of apolipoproteins in amyloidogenesis. The American Journal of Pathology. 147: 238-44. PMID 7639323  0.345
1995 Castaño EM, Prelli F, Pras M, Frangione B. Apolipoprotein E carboxyl-terminal fragments are complexed to amyloids A and L. Implications for amyloidogenesis and Alzheimer's disease. The Journal of Biological Chemistry. 270: 17610-5. PMID 7615568 DOI: 10.1074/jbc.270.29.17610  0.381
1995 Smith MA, Siedlak SL, Richey PL, Mulvihill P, Ghiso J, Frangione B, Tagliavini F, Giaccone G, Bugiani O, Praprotnik D. Tau protein directly interacts with the amyloid beta-protein precursor: implications for Alzheimer's disease. Nature Medicine. 1: 365-9. PMID 7585068 DOI: 10.1038/Nm0495-365  0.353
1995 Castano EM, Prelli F, Wisniewski T, Golabek A, Kumar RA, Soto C, Frangione B. Fibrillogenesis in Alzheimer's disease of amyloid beta peptides and apolipoprotein E. The Biochemical Journal. 306: 599-604. PMID 7534068 DOI: 10.1042/Bj3060599  0.359
1995 Wisniewski T, Palha JA, Ghiso J, Frangione B. S182 protein in Alzheimer's disease neuritic plaques. Lancet. 346: 1366. PMID 7475795 DOI: 10.1016/S0140-6736(95)92379-9  0.384
1994 Wisniewski T, Lalowski M, Levy E, Marques MR, Frangione B. The amino acid sequence of neuritic plaque amyloid from a familial Alzheimer's disease patient. Annals of Neurology. 35: 245-6. PMID 8109908 DOI: 10.1002/Ana.410350223  0.419
1994 Ghiso J, Gardella JE, Liem L, Gorevic PD, Frangione B. Characterization of a novel processing pathway for Alzheimer's amyloid beta precursor protein. Neuroscience Letters. 171: 213-6. PMID 8084490 DOI: 10.1016/0304-3940(94)90642-4  0.331
1994 Gallo G, Wisniewski T, Choi-Miura NH, Ghiso J, Frangione B. Potential role of apolipoprotein-E in fibrillogenesis. The American Journal of Pathology. 145: 526-30. PMID 8080036  0.343
1994 Tagliavini F, Prelli F, Porro M, Rossi G, Giaccone G, Farlow MR, Dlouhy SR, Ghetti B, Bugiani O, Frangione B. Amyloid fibrils in Gerstmann-Sträussler-Scheinker disease (Indiana and Swedish kindreds) express only PrP peptides encoded by the mutant allele. Cell. 79: 695-703. PMID 7954833 DOI: 10.1016/0092-8674(94)90554-1  0.438
1994 Ghiso J, Wisniewski T, Frangione B. Unifying features of systemic and cerebral amyloidosis. Molecular Neurobiology. 8: 49-64. PMID 7916192 DOI: 10.1007/Bf02778007  0.456
1994 Ghetti B, Tagliavini F, Giaccone G, Bugiani O, Frangione B, Farlow MR, Dlouhy SR. Familial Gerstmann-Sträussler-Scheinker disease with neurofibrillary tangles. Molecular Neurobiology. 8: 41-8. PMID 7916191 DOI: 10.1007/Bf02778006  0.394
1994 Wisniewski T, Ghiso J, Frangione B. Alzheimer's disease and soluble A beta. Neurobiology of Aging. 15: 143-52. PMID 7838284 DOI: 10.1016/0197-4580(94)90105-8  0.377
1994 Koudinov A, Matsubara E, Frangione B, Ghiso J. The soluble form of Alzheimer's amyloid beta protein is complexed to high density lipoprotein 3 and very high density lipoprotein in normal human plasma. Biochemical and Biophysical Research Communications. 205: 1164-71. PMID 7802646 DOI: 10.1006/Bbrc.1994.2788  0.306
1994 Frangione B, Wisniewski T, Ghiso J. Chaperoning Alzheimer's amyloids. Neurobiology of Aging. 15: S97-9. PMID 7700474 DOI: 10.1016/0197-4580(94)90182-1  0.426
1993 Goldfarb LG, Brown P, Haltia M, Ghiso J, Frangione B, Gajdusek DC. Synthetic peptides corresponding to different mutated regions of the amyloid gene in familial Creutzfeldt-Jakob disease show enhanced in vitro formation of morphologically different amyloid fibrils. Proceedings of the National Academy of Sciences of the United States of America. 90: 4451-4. PMID 8506284 DOI: 10.1073/pnas.90.10.4451  0.331
1993 Ramabhadran TV, Gandy SE, Ghiso J, Czernik AJ, Ferris D, Bhasin R, Goldgaber D, Frangione B, Greengard P. Proteolytic processing of human amyloid beta protein precursor in insect cells. Major carboxyl-terminal fragment is identical to its human counterpart. The Journal of Biological Chemistry. 268: 2009-12. PMID 8420974  0.347
1993 Tagliavini F, Giaccone G, Bugiani O, Frangione B. Ubiquitinated neurites are associated with preamyloid and cerebral amyloid beta deposits in patients with hereditary cerebral hemorrhage with amyloidosis Dutch type. Acta Neuropathologica. 85: 267-71. PMID 8384771 DOI: 10.1007/Bf00227721  0.43
1993 Tagliavini F, Giaccone G, Prelli F, Verga L, Porro M, Trojanowski JQ, Farlow MR, Frangione B, Ghetti B, Bugiani O. A68 is a component of paired helical filaments of Gerstmann-Sträussler-Scheinker disease, Indiana kindred. Brain Research. 616: 325-9. PMID 8358624 DOI: 10.1016/0006-8993(93)90226-D  0.388
1993 Ghiso J, Matsubara E, Koudinov A, Choi-Miura NH, Tomita M, Wisniewski T, Frangione B. The cerebrospinal-fluid soluble form of Alzheimer's amyloid beta is complexed to SP-40,40 (apolipoprotein J), an inhibitor of the complement membrane-attack complex. The Biochemical Journal. 293: 27-30. PMID 8328966 DOI: 10.1042/Bj2930027  0.339
1993 Wisniewski T, Castano E, Ghiso J, Frangione B. Cerebrospinal fluid inhibits Alzheimer beta-amyloid fibril formation in vitro. Annals of Neurology. 34: 631-3. PMID 8215255 DOI: 10.1002/Ana.410340422  0.408
1993 Vidal RG, Fernandez-Madrid I, Frangione B, Levy E. Sequencing of the Alzheimer's APP gene Dutch variant (APP-D) Human Mutation. 2: 496-7. PMID 8111419 DOI: 10.1002/Humu.1380020613  0.358
1993 Bugiani O, Giaccone G, Verga L, Pollo B, Frangione B, Farlow MR, Tagliavini F, Ghetti B. Beta PP participates in PrP-amyloid plaques of Gerstmann-Sträussler-Scheinker disease, Indiana kindred. Journal of Neuropathology and Experimental Neurology. 52: 64-70. PMID 8093899 DOI: 10.1097/00005072-199301000-00008  0.414
1993 Rodrigues MM, Rajagopalan S, Jones K, Nirankari V, Wisniewski T, Frangione B, Gorevic PD. Gelsolin immunoreactivity in corneal amyloid, wound healing, and macular and granular dystrophies. American Journal of Ophthalmology. 115: 644-52. PMID 7683843 DOI: 10.1016/S0002-9394(14)71464-3  0.439
1993 Giaccone G, Verga L, Bugiani O, Frangione B, Serban D, Prusiner SB, Farlow MR, Ghetti B, Tagliavini F. Corrections: Prion Protein Preamyloid and Amyloid Deposits in Gerstmann- Straussler-Scheinker Disease, Indiana Kindred Proceedings of the National Academy of Sciences of the United States of America. 90: 362. DOI: 10.1073/Pnas.90.1.362B  0.426
1992 Wisniewski T, Frangione B. Apolipoprotein E: a pathological chaperone protein in patients with cerebral and systemic amyloid. Neuroscience Letters. 135: 235-8. PMID 1625800 DOI: 10.1016/0304-3940(92)90444-C  0.406
1992 Gardella JE, Gorgone GA, Newman P, Frangione B, Gorevic PD. Characterization of Alzheimer amyloid precursor protein transcripts in platelets and megakarocytes. Neuroscience Letters. 138: 229-32. PMID 1608533  0.309
1992 Gold LI, Rostagno A, Frangione B, Passalaris T. Localization of the cleavage sites on fibronectin following digestion by urokinase. Journal of Cellular Biochemistry. 50: 441-52. PMID 1469074 DOI: 10.1002/Jcb.240500412  0.321
1992 Wisniewski T, Frangione B. Molecular biology of Alzheimer's amyloid--Dutch variant. Molecular Neurobiology. 6: 75-86. PMID 1463589 DOI: 10.1007/Bf02935567  0.465
1992 Gardella JE, Gorgone GA, Munoz PC, Ghiso J, Frangione B, Gorevic PD. Beta protein precursor expression in human platelets and a megakaryocyte cell line. Possible implications for the origin of cerebral amyloidosis in Alzheimer's disease. Laboratory Investigation; a Journal of Technical Methods and Pathology. 67: 303-13. PMID 1405489  0.308
1992 Vidal RG, Ghiso J, Gallo G, Cohen M, Gambetti PL, Frangione B. Amyloidoma of the CNS. II. Immunohistochemical and biochemical study. Neurology. 42: 2024-8. PMID 1383872 DOI: 10.1212/Wnl.42.10.2024  0.472
1992 Tagliavini F, Prelli F, Porro M, Salmona M, Bugiani O, Frangione B. A soluble form of prion protein in human cerebrospinal fluid: implications for prion-related encephalopathies. Biochemical and Biophysical Research Communications. 184: 1398-404. PMID 1375461 DOI: 10.1016/S0006-291X(05)80038-5  0.382
1992 Ghiso J, Wisniewski T, Vidal R, Rostagno A, Frangione B. Epitope map of two polyclonal antibodies that recognize amyloid lesions in patients with Alzheimer's disease. The Biochemical Journal. 282: 517-22. PMID 1372166 DOI: 10.1042/Bj2820517  0.315
1992 Giaccone G, Verga L, Bugiani O, Frangione B, Serban D, Prusiner SB, Farlow MR, Ghetti B, Tagliavini F. Prion protein preamyloid and amyloid deposits in Gerstmann-Sträussler-Scheinker disease, Indiana kindred. Proceedings of the National Academy of Sciences of the United States of America. 89: 9349-53. PMID 1357663 DOI: 10.1073/Pnas.89.19.9349  0.472
1992 Haltia M, Levy E, Meretoja J, Fernandez-Madrid I, Koivunen O, Frangione B. Gelsolin gene mutation--at codon 187--in familial amyloidosis, Finnish: DNA-diagnostic assay. American Journal of Medical Genetics. 42: 357-9. PMID 1311149 DOI: 10.1002/Ajmg.1320420321  0.368
1992 Ghiso J, Rostagno A, Gardella JE, Liem L, Gorevic PD, Frangione B. A 109-amino-acid C-terminal fragment of Alzheimer's-disease amyloid precursor protein contains a sequence, -RHDS-, that promotes cell adhesion. The Biochemical Journal. 288: 1053-9. PMID 1281980 DOI: 10.1042/Bj2881053  0.348
1992 Gardella J, Gorgone G, Frangione B, Gorevic P. In vitro autocatalytic fibrillogenesis by a recombinant Alzheimer amyloid precursor protein carboxyl-terminal construct Neurobiology of Aging. 13: S78. DOI: 10.1016/0197-4580(92)90435-Z  0.354
1991 Levy E, Frangione B. Familial Alzheimer's disease. Current Biology : Cb. 1: 312-4. PMID 15336108 DOI: 10.1016/0960-9822(91)90096-F  0.335
1991 Wisniewski T, Ghiso J, Frangione B. Peptides homologous to the amyloid protein of Alzheimer's disease containing a glutamine for glutamic acid substitution have accelerated amyloid fibril formation. Biochemical and Biophysical Research Communications. 180: 1528. PMID 1953795  0.37
1991 el Hachimi KH, Verga L, Giaccone G, Tagliavini F, Frangione B, Bugiani O, Foncin JF. Relationship between non-fibrillary amyloid precursors and cell processes in the cortical neuropil of Alzheimer patients. Neuroscience Letters. 129: 119-22. PMID 1922961 DOI: 10.1016/0304-3940(91)90734-B  0.398
1991 Tagliavini F, Giaccone G, Verga L, Ghiso J, Frangione B, Bugiani O. Alzheimer patients: preamyloid deposits are immunoreactive with antibodies to extracellular domains of the amyloid precursor protein. Neuroscience Letters. 128: 117-20. PMID 1922939 DOI: 10.1016/0304-3940(91)90773-M  0.435
1991 Wisniewski T, Haltia M, Ghiso J, Frangione B. Lewy bodies are immunoreactive with antibodies raised to gelsolin related amyloid-Finnish type. The American Journal of Pathology. 138: 1077-83. PMID 1850958  0.31
1991 Castaño EM, Wisniewski T, Frangione B. Inherited amyloids of the nervous system. Current Opinion in Neurobiology. 1: 448-54. PMID 1821690 DOI: 10.1016/0959-4388(91)90068-I  0.468
1991 Fernandez-Madrid I, Levy E, Marder K, Frangione B. Codon 618 variant of Alzheimer amyloid gene associated with inherited cerebral hemorrhage. Annals of Neurology. 30: 730-3. PMID 1763898 DOI: 10.1002/Ana.410300516  0.419
1991 Wisniewski T, Ghiso J, Frangione B. Peptides homologous to the amyloid protein of Alzheimer's disease containing a glutamine for glutamic acid substitution have accelerated amyloid fibril formation. Biochemical and Biophysical Research Communications. 179: 1247-54. PMID 1681804 DOI: 10.1016/0006-291X(91)91706-I  0.494
1991 Tagliavini F, Prelli F, Ghiso J, Bugiani O, Serban D, Prusiner SB, Farlow MR, Ghetti B, Frangione B. Amyloid protein of Gerstmann-Sträussler-Scheinker disease (Indiana kindred) is an 11 kd fragment of prion protein with an N-terminal glycine at codon 58. The Embo Journal. 10: 513-9. PMID 1672107 DOI: 10.1002/J.1460-2075.1991.Tb07977.X  0.484
1991 Haltia M, Ghiso J, Wisniewski T, Kiuru S, Miller D, Frangione B. Gelsolin variant and beta-amyloid co-occur in a case of Alzheimer's with Lewy bodies. Neurobiology of Aging. 12: 313-6. PMID 1660109 DOI: 10.1016/0197-4580(91)90007-7  0.42
1991 Gorevic PD, Munoz PC, Gorgone G, Purcell JJ, Rodrigues M, Ghiso J, Levy E, Haltia M, Frangione B. Amyloidosis due to a mutation of the gelsolin gene in an American family with lattice corneal dystrophy type II. The New England Journal of Medicine. 325: 1780-5. PMID 1658654 DOI: 10.1056/Nejm199112193252505  0.31
1990 Giaccone G, Verga L, Finazzi M, Pollo B, Tagliavini F, Frangione B, Bugiani O. Cerebral preamyloid deposits and congophilic angiopathy in aged dogs. Neuroscience Letters. 114: 178-83. PMID 2395530 DOI: 10.1016/0304-3940(90)90068-K  0.416
1990 Ghiso J, Saball E, Leoni J, Rostagno A, Frangione B. Binding of cystatin C to C4: the importance of sense-antisense peptides in their interaction. Proceedings of the National Academy of Sciences of the United States of America. 87: 1288-91. PMID 2304899 DOI: 10.1073/Pnas.87.4.1288  0.337
1990 Timmers WF, Tagliavini F, Haan J, Frangione B. Parenchymal preamyloid and amyloid deposits in the brains of patients with hereditary cerebral hemorrhage with amyloidosis--Dutch type. Neuroscience Letters. 118: 223-6. PMID 2274275 DOI: 10.1016/0304-3940(90)90632-J  0.429
1990 Prelli F, Levy E, van Duinen SG, Bots GT, Luyendijk W, Frangione B. Expression of a normal and variant Alzheimer's beta-protein gene in amyloid of hereditary cerebral hemorrhage, Dutch type: DNA and protein diagnostic assays. Biochemical and Biophysical Research Communications. 170: 301-7. PMID 2196878 DOI: 10.1016/0006-291X(90)91274-V  0.457
1990 Ghiso J, Haltia M, Prelli F, Novello J, Frangione B. Gelsolin variant (Asn-187) in familial amyloidosis, Finnish type. The Biochemical Journal. 272: 827-30. PMID 2176481 DOI: 10.1042/Bj2720827  0.307
1990 Giaccone G, Tagliavini F, Verga L, Frangione B, Farlow MR, Bugiani O, Ghetti B. Neurofibrillary tangles of the Indiana kindred of Gerstmann-Sträussler-Scheinker disease share antigenic determinants with those of Alzheimer disease. Brain Research. 530: 325-9. PMID 2176119 DOI: 10.1016/0006-8993(90)91304-Y  0.372
1990 Haltia M, Ghiso J, Prelli F, Gallo G, Kiuru S, Somer H, Palo J, Frangione B. Amyloid in familial amyloidosis, Finnish type, is antigenically and structurally related to gelsolin. The American Journal of Pathology. 136: 1223-8. PMID 2162627  0.371
1990 Haltia M, Prelli F, Ghiso J, Kiuru S, Somer H, Palo J, Frangione B. Amyloid protein in familial amyloidosis (Finnish type) is homologous to gelsolin, an actin-binding protein. Biochemical and Biophysical Research Communications. 167: 927-32. PMID 2157434 DOI: 10.1016/0006-291X(90)90612-Q  0.475
1990 Barnes JL, Goñi F, Heyermann H, Frangione B, Agnello V. Human rheumatoid factor cross-idiotypes. III. Bla monoclonal rheumatoid factor, prototype of the BLA cross-idiotype group, has distinct kappa chains related to the V kappa III subgroup and VH4 heavy chains. Arthritis and Rheumatism. 33: 1710-5. PMID 2122903 DOI: 10.1002/Art.1780331115  0.317
1990 Picken MM, Gallo GR, Pruzanski W, Frangione B. Biochemical characterization of amyloid derived from the variable region of the kappa light chain subgroup III. Arthritis and Rheumatism. 33: 880-4. PMID 2114114 DOI: 10.1002/Art.1780330616  0.425
1990 Tagliavini F, Ghiso J, Timmers WF, Giaccone G, Bugiani O, Frangione B. Coexistence of Alzheimer's amyloid precursor protein and amyloid protein in cerebral vessel walls. Laboratory Investigation; a Journal of Technical Methods and Pathology. 62: 761-7. PMID 2113597  0.356
1990 Levy E, Carman MD, Fernandez-Madrid IJ, Power MD, Lieberburg I, van Duinen SG, Bots GT, Luyendijk W, Frangione B. Mutation of the Alzheimer's disease amyloid gene in hereditary cerebral hemorrhage, Dutch type. Science (New York, N.Y.). 248: 1124-6. PMID 2111584  0.351
1990 Marangoni S, Ghiso J, Sampaio SV, Arantes EC, Giglio JR, Oliveira B, Frangione B. The complete amino acid sequence of toxin TsTX-VI isolated from the venom of the scorpion Tityus serrulatus. Journal of Protein Chemistry. 9: 595-601. PMID 2085384 DOI: 10.1007/Bf01025013  0.327
1990 Bugiani O, Giaccone G, Verga L, Pollo B, Ghetti B, Frangione B, Tagliavini F. Alzheimer patients and Down patients: abnormal presynaptic terminals are related to cerebral preamyloid deposits. Neuroscience Letters. 119: 56-9. PMID 1965862 DOI: 10.1016/0304-3940(90)90754-W  0.424
1990 Picken MM, Larrondo-Lillo M, Coria F, Gallo GR, Shelanski ML, Frangione B. Distribution of the protease inhibitor alpha 1-antichymotrypsin in cerebral and systemic amyloid. Journal of Neuropathology and Experimental Neurology. 49: 41-8. PMID 1688925 DOI: 10.1097/00005072-199001000-00005  0.457
1989 Levy E, Lopez-Otin C, Ghiso J, Geltner D, Frangione B. Stroke in Icelandic patients with hereditary amyloid angiopathy is related to a mutation in the cystatin C gene, an inhibitor of cysteine proteases. The Journal of Experimental Medicine. 169: 1771-8. PMID 2541223 DOI: 10.1084/Jem.169.5.1771  0.37
1989 Tagliavini F, Giaccone G, Linoli G, Frangione B, Bugiani O. Cerebral extracellular preamyloid deposits in Alzheimer's disease, Down syndrome and nondemented elderly individuals. Progress in Clinical and Biological Research. 317: 1001-5. PMID 2532368  0.383
1989 Verga L, Frangione B, Tagliavini F, Giaccone G, Migheli A, Bugiani O. Alzheimer patients and Down patients: cerebral preamyloid deposits differ ultrastructurally and histochemically from the amyloid of senile plaques. Neuroscience Letters. 105: 294-9. PMID 2531851 DOI: 10.1016/0304-3940(89)90636-8  0.451
1989 Giaccone G, Tagliavini F, Linoli G, Bouras C, Frigerio L, Frangione B, Bugiani O. Down patients: extracellular preamyloid deposits precede neuritic degeneration and senile plaques. Neuroscience Letters. 97: 232-8. PMID 2521927 DOI: 10.1016/0304-3940(89)90169-9  0.453
1989 Bugiani O, Giaccone G, Frangione B, Ghetti B, Tagliavini F. Alzheimer patients: preamyloid deposits are more widely distributed than senile plaques throughout the central nervous system. Neuroscience Letters. 103: 263-8. PMID 2478933 DOI: 10.1016/0304-3940(89)90110-9  0.448
1989 Ghiso J, Tagliavini F, Timmers WF, Frangione B. Alzheimer's disease amyloid precursor protein is present in senile plaques and cerebrospinal fluid: immunohistochemical and biochemical characterization. Biochemical and Biophysical Research Communications. 163: 430-7. PMID 2476128 DOI: 10.1016/0006-291X(89)92154-2  0.474
1988 Prelli F, Castaño E, Glenner GG, Frangione B. Differences between vascular and plaque core amyloid in Alzheimer's disease. Journal of Neurochemistry. 51: 648-51. PMID 3292706 DOI: 10.1111/J.1471-4159.1988.Tb01087.X  0.504
1988 Prelli F, Castaño EM, van Duinen SG, Bots GT, Luyendijk W, Frangione B. Different processing of Alzheimer's beta-protein precursor in the vessel wall of patients with hereditary cerebral hemorrhage with amyloidosis-Dutch type. Biochemical and Biophysical Research Communications. 151: 1150-5. PMID 3281669 DOI: 10.1016/S0006-291X(88)80486-8  0.473
1988 Tagliavini F, Giaccone G, Frangione B, Bugiani O. Preamyloid deposits in the cerebral cortex of patients with Alzheimer's disease and nondemented individuals. Neuroscience Letters. 93: 191-6. PMID 3241644 DOI: 10.1016/0304-3940(88)90080-8  0.455
1988 Luyendijk W, Bots GT, Vegter-van der Vlis M, Went LN, Frangione B. Hereditary cerebral haemorrhage caused by cortical amyloid angiopathy. Journal of the Neurological Sciences. 85: 267-80. PMID 3210024 DOI: 10.1016/0022-510X(88)90186-4  0.395
1988 Gallo G, Picken M, Frangione B, Buxbaum J. Nonamyloidotic monoclonal immunoglobulin deposits lack amyloid P component. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 1: 453-6. PMID 3146753  0.311
1988 Silverman GJ, Goldfien RD, Chen P, Mageed RA, Jefferis R, Goñi F, Frangione B, Fong S, Carson DA. Idiotypic and subgroup analysis of human monoclonal rheumatoid factors. Implications for structural and genetic basis of autoantibodies in humans. The Journal of Clinical Investigation. 82: 469-75. PMID 3136191 DOI: 10.1172/Jci113620  0.319
1988 Coria F, Prelli F, Castaño EM, Larrondo-Lillo M, Fernandez-Gonzalez J, van Duinen SG, Bots GT, Luyendijk W, Shelanski ML, Frangione B. Beta-protein deposition: a pathogenetic link between Alzheimer's disease and cerebral amyloid angiopathies. Brain Research. 463: 187-91. PMID 3058268 DOI: 10.1016/0006-8993(88)90545-8  0.475
1988 Coria F, Castaño E, Prelli F, Larrondo-Lillo M, van Duinen S, Shelanski ML, Frangione B. Isolation and characterization of amyloid P component from Alzheimer's disease and other types of cerebral amyloidosis. Laboratory Investigation; a Journal of Technical Methods and Pathology. 58: 454-8. PMID 2965774  0.341
1988 TAGLIAVINI F, GIACCONE G, LINOLI G, FRANGIONE B, BUGIANI O. PREAMYLOID DEPOSITS PRECEDE SENILE PLAQUE FORMATION IN THE DEVELOPMENT OF ALZHEIMER CHANGES IN DOWN SYNDROME Alzheimer Disease & Associated Disorders. 2: 405. DOI: 10.1097/00002093-198802040-00035  0.354
1988 Frangione B. Familial And Sporadic Cerebral Amyloid Angiopathy Alzheimer Disease & Associated Disorders. 2: 254. DOI: 10.1097/00002093-198802030-00103  0.349
1988 Frangione B. Human cerebral amyloidosis Drug Development Research. 15: 123-128. DOI: 10.1002/Ddr.430150205  0.462
1987 Jensson O, Gudmundsson G, Arnason A, Blöndal H, Petursdottir I, Thorsteinsson L, Grubb A, Löfberg H, Cohen D, Frangione B. Hereditary cystatin C (gamma-trace) amyloid angiopathy of the CNS causing cerebral hemorrhage. Acta Neurologica Scandinavica. 76: 102-14. PMID 3673496 DOI: 10.1111/j.1600-0404.1987.tb03553.x  0.333
1987 van Duinen SG, Castaño EM, Prelli F, Bots GT, Luyendijk W, Frangione B. Hereditary cerebral hemorrhage with amyloidosis in patients of Dutch origin is related to Alzheimer disease. Proceedings of the National Academy of Sciences of the United States of America. 84: 5991-4. PMID 3475718  0.377
1987 Prelli F, Pras M, Frangione B. Degradation and deposition of amyloid AA fibrils are tissue specific. Biochemistry. 26: 8251-6. PMID 3442653 DOI: 10.1021/Bi00399A035  0.413
1987 Coria F, Castaño EM, Frangione B. Brain amyloid in normal aging and cerebral amyloid angiopathy is antigenically related to Alzheimer's disease beta-protein. The American Journal of Pathology. 129: 422-8. PMID 3322021  0.393
1987 Gorevic PD, Castano EM, Sarma R, Frangione B. Ten to fourteen residue peptides of Alzheimer's disease protein are sufficient for amyloid fibril formation and its characteristic x-ray diffraction pattern. Biochemical and Biophysical Research Communications. 147: 854-62. PMID 3307786 DOI: 10.1016/0006-291X(87)91008-4  0.354
1986 Rostagno A, Frangione B, Pearlstein E, Garcia-Pardo A. Fibronectin binds to amyloid P component. Localization of the binding site to the 31,000 dalton C-terminal domain. Biochemical and Biophysical Research Communications. 140: 12-20. PMID 3778439 DOI: 10.1016/0006-291X(86)91051-X  0.32
1986 Gorevic PD, Goñi F, Pons-Estel B, Alvarez F, Peress NS, Frangione B. Isolation and partial characterization of neurofibrillary tangles and amyloid plaque core in Alzheimer's disease: immunohistological studies. Journal of Neuropathology and Experimental Neurology. 45: 647-64. PMID 3772397 DOI: 10.1097/00005072-198611000-00004  0.475
1986 Ghiso J, Pons-Estel B, Frangione B. Hereditary cerebral amyloid angiopathy: the amyloid fibrils contain a protein which is a variant of cystatin C, an inhibitor of lysosomal cysteine proteases. Biochemical and Biophysical Research Communications. 136: 548-54. PMID 3707586 DOI: 10.1016/0006-291X(86)90475-4  0.449
1986 Castaño EM, Ghiso J, Prelli F, Gorevic PD, Migheli A, Frangione B. In vitro formation of amyloid fibrils from two synthetic peptides of different lengths homologous to Alzheimer's disease beta-protein. Biochemical and Biophysical Research Communications. 141: 782-9. PMID 3541938 DOI: 10.1016/S0006-291X(86)80241-8  0.464
1986 Ghiso J, Jensson O, Frangione B. Amyloid fibrils in hereditary cerebral hemorrhage with amyloidosis of Icelandic type is a variant of gamma-trace basic protein (cystatin C). Proceedings of the National Academy of Sciences of the United States of America. 83: 2974-8. PMID 3517880 DOI: 10.1073/Pnas.83.9.2974  0.433
1985 Pras M, Itzchaki M, Prelli F, Dollberg L, Frangione B. Amyloid arthropathy: characterization of the amyloid protein. Clinical and Experimental Rheumatology. 3: 327-31. PMID 4085164  0.311
1985 Frangione B, Moloshok T, Prelli F, Solomon A. Human lambda light-chain constant region gene CMor lambda: the primary structure of lambda VI Bence Jones protein Mor. Proceedings of the National Academy of Sciences of the United States of America. 82: 3415-9. PMID 3923477 DOI: 10.1073/Pnas.82.10.3415  0.329
1985 Gorevic PD, Casey TT, Stone WJ, DiRaimondo CR, Prelli FC, Frangione B. Beta-2 microglobulin is an amyloidogenic protein in man. The Journal of Clinical Investigation. 76: 2425-9. PMID 3908488 DOI: 10.1172/JCI112257  0.305
1984 Garcia-Pardo A, Pearlstein E, Frangione B. Primary structure of human plasma fibronectin--characterization of the 6,000 dalton C-terminal fragment containing the interchain disulfide bridges. Biochemical and Biophysical Research Communications. 120: 1015-21. PMID 6732781 DOI: 10.1016/S0006-291X(84)80208-9  0.32
1983 Cohen DH, Feiner H, Jensson O, Frangione B. Amyloid fibril in hereditary cerebral hemorrhage with amyloidosis (HCHWA) is related to the gastroentero-pancreatic neuroendocrine protein, gamma trace. The Journal of Experimental Medicine. 158: 623-8. PMID 6886625 DOI: 10.1084/JEM.158.2.623  0.347
1983 Goñi F, Frangione B. Amino acid sequence of the Fv region of a human monoclonal IgM (protein WEA) with antibody activity against 3,4-pyruvylated galactose in Klebsiella polysaccharides K30 and K33. Proceedings of the National Academy of Sciences of the United States of America. 80: 4837-41. PMID 6410398 DOI: 10.1073/Pnas.80.15.4837  0.309
1983 Cohen D, Pras M, Franklin EC, Frangione B. Characterization of amyloid deposits and P component from a patient with factor X deficiency reveals proteins derived from a lambda VI light chain. The American Journal of Medicine. 74: 513-8. PMID 6402931 DOI: 10.1016/0002-9343(83)91000-8  0.415
1983 Pras M, Prelli F, Franklin EC, Frangione B. Primary structure of an amyloid prealbumin variant in familial polyneuropathy of Jewish origin. Proceedings of the National Academy of Sciences of the United States of America. 80: 539-42. PMID 6300852 DOI: 10.1073/PNAS.80.2.539  0.31
1982 Pras M, Franklin EC, Shibolet S, Frangione B. Amyloidosis associated with renal cell carcinoma of the AA type. The American Journal of Medicine. 73: 426-8. PMID 7124769 DOI: 10.1016/0002-9343(82)90747-1  0.383
1982 Alexander A, Steinmetz M, Barritault D, Frangione B, Franklin EC, Hood L, Buxbaum JN. gamma Heavy chain disease in man: cDNA sequence supports partial gene deletion model. Proceedings of the National Academy of Sciences of the United States of America. 79: 3260-4. PMID 6808505 DOI: 10.1073/Pnas.79.10.3260  0.362
1982 Solomon A, Frangione B, Franklin EC. Bence Jones proteins and light chains of immunoglobulins. Preferential association of the V lambda VI subgroup of human light chains with amyloidosis AL (lambda). The Journal of Clinical Investigation. 70: 453-60. PMID 6808027 DOI: 10.1172/Jci110635  0.349
1982 Mendez E, Grubb AO, Lopez C, Frangione B, Franklin EC. Human complex-forming glycoprotein, heterogeneous in charge: the primary structure around the cysteine residues and characterization of a disulfide bridge. Archives of Biochemistry and Biophysics. 213: 240-50. PMID 6174078 DOI: 10.1016/0003-9861(82)90458-1  0.349
1981 Schenkein I, Franklin EC, Frangione B. Proteolytic enzymes from the mouse submaxillary gland: a partial sequence and demonstration of spontaneous cleavages. Archives of Biochemistry and Biophysics. 209: 57-62. PMID 7025761 DOI: 10.1016/0003-9861(81)90256-3  0.322
1981 Frangione B, Rosenwasser E, Penefsky HS, Pullman ME. Amino acid sequence of the protein inhibitor of mitochondrial adenosine triphosphatase. Proceedings of the National Academy of Sciences of the United States of America. 78: 7403-7. PMID 6461003 DOI: 10.1073/Pnas.78.12.7403  0.325
1980 Frangione B, Rosenwasser E, Prelli F, Franklin EC. Primary structure of human gamma 3 immunoglobulin deletion mutant: gamma 3 heavy-chain disease protein Wis. Biochemistry. 19: 4304-8. PMID 6774747 DOI: 10.1021/Bi00559A024  0.364
1980 Pras M, Zaretzky J, Frangione B, Franklin EC. AA protein in a case of "primary" or "idiopathic" amyloidosis. The American Journal of Medicine. 68: 291-4. PMID 6766664 DOI: 10.1016/0002-9343(80)90369-1  0.444
1980 Kabat EA, Liao J, Bretting H, Franklin EC, Geltner D, Frangione B, Koshland ME, Shyong J, Osserman EF. Human monoclonal macroglobulins with specificity for Klebsiella K polysaccharides that contain 3,4-pyruvylated-D-galactose and 4,6-pyruvylated-D-galactose. The Journal of Experimental Medicine. 152: 979-95. PMID 6158553 DOI: 10.1084/Jem.152.4.979  0.308
1980 Pardo AG, Lamm ME, Plaut AG, Frangione B. Secretory component is convalently bound to a single sub-unit in human secretory IgA. Molecular Immunology. 16: 477-82. PMID 500111 DOI: 10.1016/0161-5890(79)90073-7  0.334
1979 Franklin EC, Kyle R, Seligmann M, Frangione B. Correlation of protein structure and immunoglobulin gene organization in the light of two new deleted heavy chain disease proteins. Molecular Immunology. 16: 919-21. PMID 118919 DOI: 10.1016/0161-5890(79)90090-7  0.347
1979 Franklin EC, Prelli F, Frangione B. Human heavy chain disease protein WIS: implications for the organization of immunoglobulin genes. Proceedings of the National Academy of Sciences of the United States of America. 76: 452-6. PMID 106391 DOI: 10.1073/Pnas.76.1.452  0.347
1979 Gorevic PD, Levo Y, Chatpar PC, Frangione B, Franklin EC. Some effects of the administration of endotoxin in mice. Specific cleavage of serum albumin by an acid protease and the generation of amyloid serum component. The Journal of Clinical Investigation. 63: 254-61. PMID 34628 DOI: 10.1172/Jci109297  0.324
1977 Schenkein I, Levy M, Franklin EC, Frangione B. Proteolytic enzymes from the mouse submaxillary gland. Specificity restricted to arginine residues. Archives of Biochemistry and Biophysics. 182: 64-70. PMID 883839 DOI: 10.1016/0003-9861(77)90283-1  0.322
1976 Frangione B, Franklin EC, Grubb A, Tejler L. The amino-terminal sequence of human protein HC. Febs Letters. 70: 239-40. PMID 992067 DOI: 10.1016/0014-5793(76)80765-X  0.313
1976 Frangione B. A new immunoglobulin variant: gamma3 heavy chain disease protein CHI. Proceedings of the National Academy of Sciences of the United States of America. 73: 1552-5. PMID 818639 DOI: 10.1073/Pnas.73.5.1552  0.346
1975 Wolfenstein-Todel C, Mihaesco E, Frangione B. Variant of a human immunoglobulin: "alpha chain disease" protein AIT. Biochemical and Biophysical Research Communications. 65: 47-53. PMID 807216 DOI: 10.1016/S0006-291X(75)80059-3  0.358
1975 Adlersberg JB, Franklin EC, Frangione B. Repetitive hinge region sequences in human IgG3: isolation of an 11,000-dalton fragment. Proceedings of the National Academy of Sciences of the United States of America. 72: 723-7. PMID 804697 DOI: 10.1073/Pnas.72.2.723  0.352
1975 Wolfenstein-Todel C, Frangione B, Franklin EC. Partial amino acid sequence of an IgA2 human immunoglobulin heavy chain. Biochimica Et Biophysica Acta. 379: 627-37. PMID 804325 DOI: 10.1016/0005-2795(75)90169-5  0.329
1974 Wolfenstein-Todel C, Prelli F, Frangione B, Franklin EC. Immunoglobulin A. Arrangement of disulfide bridges in the "hinge" region of an immunoglobulin lin A-1 human myeloma protein. Biochemistry. 12: 5195-7. PMID 4601226 DOI: 10.1021/Bi00749A028  0.305
1974 Wolfenstein-Todel C, Mihaesco E, Frangione B. "Alpha chain disease" protein def: internal deletion of a human immunoglobulin A1 heavy chain. Proceedings of the National Academy of Sciences of the United States of America. 71: 974-8. PMID 4595579 DOI: 10.1073/Pnas.71.3.974  0.335
1974 Mendez E, Prelli F, Frangione B, Franklin EC. Characterization of a disulfide bridge linking the J chain to the alpha chain of polymeric immunoglobulin A. Biochemical and Biophysical Research Communications. 55: 1291-7. PMID 4203905 DOI: 10.1016/S0006-291X(73)80034-8  0.327
1973 Mendez E, Frangione B, Franklin EC. Structure of immunoglobulin A. Amino acid sequence of cysteine-containing peptides from the J chain Biochemistry. 12: 1119-1124. PMID 4631861 DOI: 10.1021/Bi00730A016  0.366
1973 Frangione B, Lee L, Haber E, Bloch KJ. Protein Hal: partial deletion of a " " immunoglobulin gene(s) and apparent reinitiation at an internal AUG codon. Proceedings of the National Academy of Sciences of the United States of America. 70: 1073-7. PMID 4577790 DOI: 10.1073/Pnas.70.4.1073  0.367
1973 Frangione B, Wolfenstein-Todel C. Partial duplication in the "hinge" region of IgA 1 myeloma proteins. Proceedings of the National Academy of Sciences of the United States of America. 69: 3673-6. PMID 4509329 DOI: 10.1073/Pnas.69.12.3673  0.308
1973 Mendez E, Frangione B, Franklin EC. Structure of immunoglobulin A. Cysteine-containing peptides of the α chain of an immunoglobulin A1 myeloma protein Biochemistry. 12: 5186-5194. PMID 4210018 DOI: 10.1021/Bi00749A027  0.362
1972 Levin M, Franklin EC, Frangione B, Pras M. The amino acid sequence of a major nonimmunoglobulin component of some amyloid fibrils. The Journal of Clinical Investigation. 51: 2773-6. PMID 5056669 DOI: 10.1172/Jci107098  0.389
1972 Cooper SM, Franklin EC, Frangione B. Molecular defect in a gamma-2 (γ2) heavy chain Science. 176: 187-189. PMID 4111345 DOI: 10.1126/Science.176.4031.187  0.346
1971 Mihaescon E, Seligman M, Frangione B. Heavy-light chain disulphide bridge common to A1 and a genetic variant of A2 immunoglobulins. Nature: New Biology. 232: 220-1. PMID 5285756 DOI: 10.1038/Newbio232220A0  0.304
1971 Irimajiri S, Franklin EC, Frangione B. Some chemical and biological properties of the F'c fragment of human gamma-G globulins. Immunochemistry. 5: 383-97. PMID 4997109 DOI: 10.1016/0019-2791(68)90133-X  0.371
1971 Milstein C, Frangione B. Disulphide bridges of the heavy chain of human immunoglobulin G2. The Biochemical Journal. 121: 217-25. PMID 4940472  0.502
1969 Frangione B, Milstein C, Pink JR. Structural studies of immunoglobulin G. Nature. 221: 145-8. PMID 5782707  0.388
1969 Frangione B, Milstein C, Franklin EC. Chemical typing of immunoglobulins. Nature. 221: 149-51. PMID 4882223  0.39
1969 Frangione B, Milstein C. Partial deletion in the heavy chain disease protein ZUC. Nature. 224: 597-9. PMID 4186690  0.486
1968 Frangione B, Milstein C, Franklin EC. Intrachain disulphide bridges in immunoglobulin G heavy chains. The Fc fragment. The Biochemical Journal. 106: 15-21. PMID 4889360  0.477
1968 Frangione B, Milstein C. Variations in the S-S bridges of immunoglobins G: interchain disulfide bridges of gamma G3 myeloma proteins. Journal of Molecular Biology. 33: 893-906. PMID 4178186 DOI: 10.1016/0022-2836(68)90326-4  0.476
1967 Frangione B, Milstein C. Disulphide bridges of immunoglobin G-1 heavy chains. Nature. 216: 939-41. PMID 4169396  0.407
1967 Merryman C, Frangione B, Franklin EC, Benacerraf B. Peptide differences in purified mouse antibodies. Immunochemistry. 4: 31-6. PMID 4166160 DOI: 10.1016/0019-2791(67)90194-2  0.31
1967 Frangione B, Franklin EC, Fudenberg HH, Koshland ME. Structural studies of human gamma-G-myeloma proteins of different antigenic subgroups and genetic specificities. The Journal of Experimental Medicine. 124: 715-32. PMID 4162448 DOI: 10.1084/Jem.124.4.715  0.37
1967 Milstein C, Frangione B, Pink JRL. Studies on the Variability of Immunoglobulin Sequence Cold Spring Harbor Symposia On Quantitative Biology. 32: 31-36. DOI: 10.1101/SQB.1967.032.01.007  0.399
1965 Frangione B, Franklin EC. Structural Studies Of Human Immunoglobulins. Differences In The Fd Fragments Of The Heavy Chains Of G Myeloma Proteins. Journal of Experimental Medicine. 122: 1-10. PMID 14325471 DOI: 10.1084/Jem.122.1.1  0.372
1965 Frangione B, Franklin EC. Structural studies of human immunoglobulins: Differences in the primary structure of heavy chains of normal and pathologic G, A, and M immunoglobulins☆ Archives of Biochemistry and Biophysics. 111: 603-613. PMID 4159529 DOI: 10.1016/0003-9861(65)90241-9  0.31
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