Year |
Citation |
Score |
2019 |
Ryan KM, Boyle NT, Harkin A, Connor TJ. Dexamethasone attenuates inflammatory-mediated suppression of β-adrenoceptor expression in rat primary mixed glia. Journal of Neuroimmunology. 338: 577082. PMID 31707103 DOI: 10.1016/J.Jneuroim.2019.577082 |
0.371 |
|
2019 |
Duda W, Curzytek K, Kubera M, Connor TJ, Fagan EM, Basta-Kaim A, Trojan E, Papp M, Gruca P, Budziszewska B, Leśkiewicz M, Maes M, Lasoń W. Interaction of the immune-inflammatory and the kynurenine pathways in rats resistant to antidepressant treatment in model of depression. International Immunopharmacology. 73: 527-538. PMID 31176083 DOI: 10.1016/j.intimp.2019.05.039 |
0.407 |
|
2018 |
Yssel JD, O'Neill E, Nolan YM, Connor TJ, Harkin A. Treatment with the noradrenaline re-uptake inhibitor atomoxetine alone and in combination with the α2-adrenoceptor antagonist idazoxan attenuates loss of dopamine and associated motor deficits in the LPS inflammatory rat model of Parkinson's disease. Brain, Behavior, and Immunity. PMID 29339319 DOI: 10.1016/J.Bbi.2018.01.004 |
0.37 |
|
2018 |
Griffin ÉW, Yssel JD, O'Neill E, Ryan KJ, Boyle N, Harper P, Harkin A, Connor T. The β2-adrenoceptor agonist clenbuterol reduces the neuroinflammatory response, neutrophil infiltration and apoptosis following intra-striatal IL-1β administration to rats. Immunopharmacology and Immunotoxicology. 1-8. PMID 29303018 DOI: 10.1080/08923973.2017.1418882 |
0.37 |
|
2017 |
O'Farrell K, Fagan E, Connor TJ, Harkin A. Inhibition of the kynurenine pathway protects against reactive microglial-associated reductions in the complexity of primary cortical neurons. European Journal of Pharmacology. PMID 28688912 DOI: 10.1016/J.Ejphar.2017.07.008 |
0.319 |
|
2016 |
O'Neill E, Kwok B, Day JS, Connor TJ, Harkin A. Amitriptyline protects against TNF-α-induced atrophy and reduction in synaptic markers via a Trk-dependent mechanism. Pharmacology Research & Perspectives. 4: e00195. PMID 27069625 DOI: 10.1002/Prp2.195 |
0.313 |
|
2016 |
Ryan KM, Griffin ÉW, Ryan KJ, Tanveer R, Vanattou-Saifoudine N, McNamee EN, Fallon E, Heffernan S, Harkin A, Connor TJ. Clenbuterol activates the central IL-1 system via the β2-adrenoceptor without provoking inflammatory response related behaviours in rats. Brain, Behavior, and Immunity. PMID 26928198 DOI: 10.1016/J.Bbi.2016.02.023 |
0.418 |
|
2016 |
Hughes MM, Connor TJ, Harkin A. Stress-related immune markers in depression: implications for treatment. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). PMID 26775294 DOI: 10.1093/Ijnp/Pyw001 |
0.339 |
|
2014 |
Gigliucci V, Gormley S, Gibney S, Rouine J, Kerskens C, Connor TJ, Harkin A. Characterisation of the antidepressant properties of nitric oxide synthase inhibitors in the olfactory bulbectomised rat model of depression. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 24: 1349-61. PMID 24931298 DOI: 10.1016/J.Euroneuro.2014.05.003 |
0.328 |
|
2014 |
Gibney SM, Fagan EM, Waldron AM, O'Byrne J, Connor TJ, Harkin A. Inhibition of stress-induced hepatic tryptophan 2,3-dioxygenase exhibits antidepressant activity in an animal model of depressive behaviour. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 17: 917-28. PMID 24472498 DOI: 10.1017/S1461145713001673 |
0.384 |
|
2014 |
Day JS, O'Neill E, Cawley C, Aretz NK, Kilroy D, Gibney SM, Harkin A, Connor TJ. Noradrenaline acting on astrocytic β₂-adrenoceptors induces neurite outgrowth in primary cortical neurons. Neuropharmacology. 77: 234-48. PMID 24126345 DOI: 10.1016/J.Neuropharm.2013.09.027 |
0.308 |
|
2014 |
Duda W, Curzytek K, Kubera M, Fagan E, Connor TJ. P.1.002 Alterations of the kynurenine pathway in rat chronic mild stress model European Neuropsychopharmacology. 24. DOI: 10.1016/S0924-977X(14)70005-7 |
0.307 |
|
2014 |
O'Neill E, Day J, Connor T, Harkin A. Noradrenaline-mediated protection against TNF-alpha-induced neuronal atrophy Journal of Neuroimmunology. 275: 167. DOI: 10.1016/J.Jneuroim.2014.08.448 |
0.329 |
|
2013 |
Pertl MM, Hevey D, Boyle NT, Hughes MM, Collier S, O'Dwyer AM, Harkin A, Kennedy MJ, Connor TJ. C-reactive protein predicts fatigue independently of depression in breast cancer patients prior to chemotherapy. Brain, Behavior, and Immunity. 34: 108-19. PMID 23928287 DOI: 10.1016/J.Bbi.2013.07.177 |
0.351 |
|
2013 |
Ryan KJ, Griffin É, Yssel JD, Ryan KM, McNamee EN, Harkin A, Connor TJ. Stimulation of central β2-adrenoceptors suppresses NFκB activity in rat brain: a role for IκB. Neurochemistry International. 63: 368-78. PMID 23896303 DOI: 10.1016/J.Neuint.2013.07.006 |
0.335 |
|
2013 |
Kelly RJ, Minogue AM, Lyons A, Jones RS, Browne TC, Costello DA, Denieffe S, O'Sullivan C, Connor TJ, Lynch MA. Glial Activation in AβPP/PS1 Mice is Associated with Infiltration of IFNγ-Producing Cells. Journal of Alzheimer's Disease : Jad. PMID 23780663 DOI: 10.3233/JAD-130539 |
0.307 |
|
2013 |
Downer EJ, Jones RS, McDonald CL, Greco E, Brennan S, Connor TJ, Robertson IH, Lynch MA. Identifying early inflammatory changes in monocyte-derived macrophages from a population with IQ-discrepant episodic memory. Plos One. 8: e63194. PMID 23671673 DOI: 10.1371/journal.pone.0063194 |
0.344 |
|
2013 |
Gibney SM, McGuinness B, Prendergast C, Harkin A, Connor TJ. Poly I:C-induced activation of the immune response is accompanied by depression and anxiety-like behaviours, kynurenine pathway activation and reduced BDNF expression. Brain, Behavior, and Immunity. 28: 170-81. PMID 23201589 DOI: 10.1016/J.Bbi.2012.11.010 |
0.383 |
|
2013 |
Hughes M, Carballedo A, McLoughlin D, Frodl T, Connor T. 111. Childhood trauma and depression are associated with a dysregulated inflammatory profile Brain, Behavior, and Immunity. 32: e32. DOI: 10.1016/J.Bbi.2013.07.123 |
0.357 |
|
2013 |
Fagan EM, Gibney SM, Connor TJ. 96. Anti-depressants and kynurenine pathway inhibition: A therapeutic strategy for neuroprotection in vitro? Brain Behavior and Immunity. 32. DOI: 10.1016/J.Bbi.2013.07.108 |
0.38 |
|
2013 |
Fagan EM, Dempsey C, Tallon E, Connor TJ. 81. IFN-alpha and IL-6 reduce glucocorticoid sensitivity in murine microglia: A role for FKBP5? Brain Behavior and Immunity. 32. DOI: 10.1016/J.Bbi.2013.07.093 |
0.398 |
|
2012 |
Browne CA, O'Brien FE, Connor TJ, Dinan TG, Cryan JF. Differential lipopolysaccharide-induced immune alterations in the hippocampus of two mouse strains: effects of stress. Neuroscience. 225: 237-48. PMID 22917616 DOI: 10.1016/j.neuroscience.2012.08.031 |
0.593 |
|
2012 |
Beumer W, Gibney SM, Drexhage RC, Pont-Lezica L, Doorduin J, Klein HC, Steiner J, Connor TJ, Harkin A, Versnel MA, Drexhage HA. The immune theory of psychiatric diseases: a key role for activated microglia and circulating monocytes. Journal of Leukocyte Biology. 92: 959-75. PMID 22875882 DOI: 10.1189/Jlb.0212100 |
0.328 |
|
2012 |
Frodl T, Carballedo A, Hughes MM, Saleh K, Fagan A, Skokauskas N, McLoughlin DM, Meaney J, O'Keane V, Connor TJ. Reduced expression of glucocorticoid-inducible genes GILZ and SGK-1: high IL-6 levels are associated with reduced hippocampal volumes in major depressive disorder. Translational Psychiatry. 2: e88. PMID 22832853 DOI: 10.1038/Tp.2012.14 |
0.394 |
|
2012 |
Hughes MM, Carballedo A, McLoughlin DM, Amico F, Harkin A, Frodl T, Connor TJ. Tryptophan depletion in depressed patients occurs independent of kynurenine pathway activation. Brain, Behavior, and Immunity. 26: 979-87. PMID 22683764 DOI: 10.1016/J.Bbi.2012.05.010 |
0.398 |
|
2012 |
Kerr DM, Burke NN, Ford GK, Connor TJ, Harhen B, Egan LJ, Finn DP, Roche M. Pharmacological inhibition of endocannabinoid degradation modulates the expression of inflammatory mediators in the hypothalamus following an immunological stressor. Neuroscience. 204: 53-63. PMID 21952131 DOI: 10.1016/j.neuroscience.2011.09.032 |
0.438 |
|
2011 |
Ryan KJ, Griffin EW, Connor TJ. Complementary anti-inflammatory actions of the β₂-adrenoceptor agonist clenbuterol and the glucocorticoid dexamethasone in rat brain. Journal of Neuroimmunology. 232: 209-16. PMID 21035874 DOI: 10.1016/j.jneuroim.2010.10.001 |
0.378 |
|
2011 |
Gibney S, McGuinness B, Prendergast C, Harkin A, Connor T. 149. Poly I:C-induced activation of the innate immune response is accompanied by symptoms of depression and anxiety Brain, Behavior, and Immunity. 25: S222. DOI: 10.1016/J.Bbi.2011.07.152 |
0.315 |
|
2010 |
Boyle NT, Connor TJ. Methylenedioxymethamphetamine ('Ecstasy')-induced immunosuppression: a cause for concern? British Journal of Pharmacology. 161: 17-32. PMID 20718737 DOI: 10.1111/j.1476-5381.2010.00899.x |
0.399 |
|
2010 |
Gleeson LC, Ryan KJ, Griffin EW, Connor TJ, Harkin A. The β2-adrenoceptor agonist clenbuterol elicits neuroprotective, anti-inflammatory and neurotrophic actions in the kainic acid model of excitotoxicity. Brain, Behavior, and Immunity. 24: 1354-61. PMID 20599496 DOI: 10.1016/J.Bbi.2010.06.015 |
0.41 |
|
2010 |
McNamee EN, Griffin EW, Ryan KM, Ryan KJ, Heffernan S, Harkin A, Connor TJ. Noradrenaline acting at beta-adrenoceptors induces expression of IL-1beta and its negative regulators IL-1ra and IL-1RII, and drives an overall anti-inflammatory phenotype in rat cortex. Neuropharmacology. 59: 37-48. PMID 20361987 DOI: 10.1016/J.Neuropharm.2010.03.014 |
0.404 |
|
2010 |
McNamee EN, Ryan KM, Griffin EW, González-Reyes RE, Ryan KJ, Harkin A, Connor TJ. Noradrenaline acting at central beta-adrenoceptors induces interleukin-10 and suppressor of cytokine signaling-3 expression in rat brain: implications for neurodegeneration. Brain, Behavior, and Immunity. 24: 660-71. PMID 20193756 DOI: 10.1016/J.Bbi.2010.02.005 |
0.438 |
|
2010 |
Campbell SJ, Meier U, Mardiguian S, Jiang Y, Littleton ET, Bristow A, Relton J, Connor TJ, Anthony DC. Sickness behaviour is induced by a peripheral CXC-chemokine also expressed in multiple sclerosis and EAE. Brain, Behavior, and Immunity. 24: 738-46. PMID 20138139 DOI: 10.1016/J.Bbi.2010.01.011 |
0.345 |
|
2010 |
O'Sullivan JB, Ryan KM, Harkin A, Connor TJ. Noradrenaline reuptake inhibitors inhibit expression of chemokines IP-10 and RANTES and cell adhesion molecules VCAM-1 and ICAM-1 in the CNS following a systemic inflammatory challenge. Journal of Neuroimmunology. 220: 34-42. PMID 20061033 DOI: 10.1016/J.Jneuroim.2009.12.007 |
0.364 |
|
2010 |
McNamee EN, Ryan KM, Kilroy D, Connor TJ. Noradrenaline induces IL-1ra and IL-1 type II receptor expression in primary glial cells and protects against IL-1beta-induced neurotoxicity. European Journal of Pharmacology. 626: 219-28. PMID 19818755 DOI: 10.1016/j.ejphar.2009.09.054 |
0.344 |
|
2010 |
Hughes M, Dunne R, Noone M, McLoughlin D, Connor T. Inflammatory gene expression profile in treatment resistant depression Brain, Behavior, and Immunity. 24: S62-S63. DOI: 10.1016/J.Bbi.2010.07.207 |
0.302 |
|
2010 |
Griffin EW, Ryan KJ, Connor TJ. Synergistic CNS anti-inflammatory actions of combined treatment with the beta2-adrenoceptor agonist clenbuterol and the glucocorticoid dexamethasone Brain Behavior and Immunity. 24. DOI: 10.1016/J.Bbi.2010.07.156 |
0.324 |
|
2010 |
Ryan KJ, Ryan KM, Griffin EW, McNamee EN, Harkin A, Connor TJ. A role for central IL-1beta in the suppression of locomotor activity induced the by the beta2-adrenoceptor agonist clenbuterol? Brain Behavior and Immunity. 24. DOI: 10.1016/J.Bbi.2010.07.007 |
0.332 |
|
2009 |
Curtin NM, Boyle NT, Mills KH, Connor TJ. Psychological stress suppresses innate IFN-gamma production via glucocorticoid receptor activation: reversal by the anxiolytic chlordiazepoxide. Brain, Behavior, and Immunity. 23: 535-47. PMID 19217938 DOI: 10.1016/j.bbi.2009.02.003 |
0.393 |
|
2009 |
Curtin NM, Mills KH, Connor TJ. Psychological stress increases expression of IL-10 and its homolog IL-19 via beta-adrenoceptor activation: reversal by the anxiolytic chlordiazepoxide. Brain, Behavior, and Immunity. 23: 371-9. PMID 19159673 DOI: 10.1016/j.bbi.2008.12.010 |
0.4 |
|
2009 |
O'Sullivan JB, Ryan KM, Curtin NM, Harkin A, Connor TJ. Noradrenaline reuptake inhibitors limit neuroinflammation in rat cortex following a systemic inflammatory challenge: implications for depression and neurodegeneration. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 12: 687-99. PMID 19046481 DOI: 10.1017/S146114570800967X |
0.448 |
|
2009 |
Ryan KM, Harkin A, Connor TJ. 107. A systemic LPS challenge does not alter central Beta2-adrenoceptor expression or reponsiveness Brain Behavior and Immunity. 23. DOI: 10.1016/J.Bbi.2009.06.112 |
0.311 |
|
2009 |
Kilroy D, Connor TJ. 67. The beta2-adrenoceptor agonist salmeterol inhibits thrombin-induced inflammation in primary glial cells: A role for PKA and EPAC activation by camp Brain Behavior and Immunity. 23. DOI: 10.1016/J.Bbi.2009.06.072 |
0.326 |
|
2008 |
Connor TJ. Don't stress out your immune system - just relax. Brain, Behavior, and Immunity. 22: 1128-9. PMID 18708135 DOI: 10.1016/j.bbi.2008.07.009 |
0.37 |
|
2008 |
Connor TJ, Starr N, O'Sullivan JB, Harkin A. Induction of indolamine 2,3-dioxygenase and kynurenine 3-monooxygenase in rat brain following a systemic inflammatory challenge: a role for IFN-gamma? Neuroscience Letters. 441: 29-34. PMID 18584961 DOI: 10.1016/J.Neulet.2008.06.007 |
0.395 |
|
2008 |
Browne C, O'Brien F, Connor T, Cryan J. P.2.10 Aberrant cytokine response to stress in BALB/c mice after lipopolysaccharide (LPS) challenge: relevance of tryptophan hydroxylase 2 European Neuropsychopharmacology. 18: s44-s45. DOI: 10.1016/S0924-977X(08)70051-8 |
0.557 |
|
2008 |
McNamee EN, González-Reyes RE, Harkin A, Connor TJ. 125. Pharmacological enhancement of central noradrenergic tone induces IL-10 production and signalling in rat brain: A role for β-adrenoceptor activation Brain Behavior and Immunity. 22: 40. DOI: 10.1016/J.Bbi.2008.04.127 |
0.359 |
|
2008 |
Ryan KM, McNamee EN, Connor TJ. 85. The glucocorticoid dexamethasone prevents inflammation-induced suppression of glial β2-adrencoceptor expression: Implications for multiple sclerosis Brain Behavior and Immunity. 22: 26-27. DOI: 10.1016/J.Bbi.2008.04.086 |
0.306 |
|
2008 |
Curtin N, Mills K, Connor T. 45. Chronic stress reduces glucocorticoid and α-adrenergic receptor expression, and induces an inflammatory state characterised by increased IL-12 and IFN-γ production Brain Behavior and Immunity. 22: 12-13. DOI: 10.1016/J.Bbi.2008.04.045 |
0.377 |
|
2007 |
Boyle NT, Connor TJ. MDMA ("Ecstasy") suppresses the innate IFN-gamma response in vivo: a critical role for the anti-inflammatory cytokine IL-10. European Journal of Pharmacology. 572: 228-38. PMID 17689526 DOI: 10.1016/j.ejphar.2007.07.020 |
0.399 |
|
2007 |
Curtin NM, Connor TJ, Mills KHG. P.1.40 Psychological stress increases production of IL-10 and IL-19: A role for the sympathetic neurotransmitter noradrenaline European Neuropsychopharmacology. 17. DOI: 10.1016/S0924-977X(07)70041-X |
0.333 |
|
2006 |
Horrigan LA, Kelly JP, Connor TJ. Immunomodulatory effects of caffeine: friend or foe? Pharmacology & Therapeutics. 111: 877-92. PMID 16540173 DOI: 10.1016/j.pharmthera.2006.02.002 |
0.397 |
|
2006 |
Diamond M, Kelly JP, Connor TJ. Antidepressants suppress production of the Th1 cytokine interferon-gamma, independent of monoamine transporter blockade. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 16: 481-90. PMID 16388933 DOI: 10.1016/j.euroneuro.2005.11.011 |
0.409 |
|
2006 |
O’Sullivan JB, Connor TJ. The noradrenaline re-uptake inhibitor desipramine limits pro-inflammatory cytokine production in rat cortex in vivo Brain Behavior and Immunity. 20: 53. DOI: 10.1016/J.Bbi.2006.04.100 |
0.358 |
|
2006 |
Boyle NT, Connor TJ. MDMA (“Ecstasy”) suppresses the innate IFN-g response, and inhibits MHC class II and co-stimulatory molecule expression on antigen presenting cells: A role for IL-10? Brain Behavior and Immunity. 20: 5-6. DOI: 10.1016/J.Bbi.2006.04.010 |
0.315 |
|
2005 |
Corcoran C, Connor TJ, O'Keane V, Garland MR. The effects of vagus nerve stimulation on pro- and anti-inflammatory cytokines in humans: a preliminary report. Neuroimmunomodulation. 12: 307-9. PMID 16166810 DOI: 10.1159/000087109 |
0.397 |
|
2005 |
Connor TJ, Brewer C, Kelly JP, Harkin A. Acute stress suppresses pro-inflammatory cytokines TNF-alpha and IL-1 beta independent of a catecholamine-driven increase in IL-10 production. Journal of Neuroimmunology. 159: 119-28. PMID 15652410 DOI: 10.1016/J.Jneuroim.2004.10.016 |
0.431 |
|
2005 |
Connor TJ, Harkin A, Kelly JP. Methylenedioxymethamphetamine suppresses production of the proinflammatory cytokine tumor necrosis factor-alpha independent of a beta-adrenoceptor-mediated increase in interleukin-10. The Journal of Pharmacology and Experimental Therapeutics. 312: 134-43. PMID 15331655 DOI: 10.1124/Jpet.104.073023 |
0.435 |
|
2004 |
Horrigan LA, Kelly JP, Connor TJ. Caffeine suppresses TNF-alpha production via activation of the cyclic AMP/protein kinase A pathway. International Immunopharmacology. 4: 1409-17. PMID 15313438 DOI: 10.1016/j.intimp.2004.06.005 |
0.385 |
|
2004 |
Harkin A, Connor TJ, Burns MP, Kelly JP. Nitric oxide synthase inhibitors augment the effects of serotonin re-uptake inhibitors in the forced swimming test. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 14: 274-81. PMID 15163436 DOI: 10.1016/J.Euroneuro.2003.08.010 |
0.61 |
|
2004 |
Connor TJ. Methylenedioxymethamphetamine (MDMA, 'Ecstasy'): a stressor on the immune system. Immunology. 111: 357-67. PMID 15056370 DOI: 10.1111/j.0019-2805.2004.01847.x |
0.379 |
|
2003 |
Harkin A, Hynes MJ, Masterson E, Kelly JP, O'Donnell JM, Connor TJ. A toxicokinetic study of nickel-induced immunosuppression in rats. Immunopharmacology and Immunotoxicology. 25: 655-70. PMID 14686805 DOI: 10.1081/Iph-120026448 |
0.407 |
|
2003 |
Harkin A, Shanahan E, Kelly JP, Connor TJ. Methylenendioxyamphetamine produces serotonin nerve terminal loss and diminished behavioural and neurochemical responses to the antidepressant fluoxetine. The European Journal of Neuroscience. 18: 1021-7. PMID 12925028 DOI: 10.1046/J.1460-9568.2003.02802.X |
0.34 |
|
2003 |
Harkin A, Connor TJ, Walsh M, St John N, Kelly JP. Serotonergic mediation of the antidepressant-like effects of nitric oxide synthase inhibitors. Neuropharmacology. 44: 616-23. PMID 12668047 DOI: 10.1016/S0028-3908(03)00030-3 |
0.348 |
|
2002 |
Connor TJ, O'Sullivan J, Nolan Y, Kelly JP. Inhibition of constitutive nitric oxide production increases the severity of lipopolysaccharide-induced sickness behaviour: a role for TNF-alpha. Neuroimmunomodulation. 10: 367-78. PMID 12907844 DOI: 10.1159/000071478 |
0.421 |
|
2002 |
Connor TJ, Kelly JP. Fenfluramine-induced immunosuppression: an in vivo analysis. European Journal of Pharmacology. 455: 175-85. PMID 12445584 DOI: 10.1016/S0014-2999(02)02588-8 |
0.4 |
|
2002 |
Harkin A, Connor TJ, O'Donnell JM, Kelly JP. Physiological and behavioral responses to stress: what does a rat find stressful? Lab Animal. 31: 42-50. PMID 11927961 DOI: 10.1038/5000150 |
0.316 |
|
2001 |
Connor TJ, Connelly DB, Kelly JP. Methylenedioxymethamphetamine (MDMA; 'Ecstasy') suppresses antigen specific IgG2a and IFN-gamma production. Immunology Letters. 78: 67-73. PMID 11672589 DOI: 10.1016/S0165-2478(01)00231-0 |
0.335 |
|
2001 |
Harkin A, Connor TJ, Mulrooney J, Kelly JP, Leonard BE. Prior exposure to methylenedioxyamphetamine (MDA) induces serotonergic loss and changes in spontaneous exploratory and amphetamine-induced behaviors in rats. Life Sciences. 68: 1367-82. PMID 11388689 DOI: 10.1016/S0024-3205(00)01039-0 |
0.501 |
|
2001 |
Connor TJ, Dennedy MC, Harkin A, Kelly JP. Methylenedioxymethamphetamine-induced suppression of interleukin-1beta and tumour necrosis factor-alpha is not mediated by serotonin. European Journal of Pharmacology. 418: 147-52. PMID 11334877 DOI: 10.1016/S0014-2999(01)00928-1 |
0.399 |
|
2000 |
Nolan Y, Connor TJ, Kelly JP, Leonard BE. Lipopolysaccharide administration produces time-dependent and region-specific alterations in tryptophan and tyrosine hydroxylase activities in rat brain. Journal of Neural Transmission (Vienna, Austria : 1996). 107: 1393-401. PMID 11458992 DOI: 10.1007/s007020070003 |
0.523 |
|
2000 |
Connor TJ, Kelly JP, McGee M, Leonard BE. Methylenedioxymethamphetamine (MDMA; Ecstasy) suppresses IL-1beta and TNF-alpha secretion following an in vivo lipopolysaccharide challenge. Life Sciences. 67: 1601-12. PMID 10983854 DOI: 10.1016/S0024-3205(00)00743-8 |
0.539 |
|
2000 |
Kelliher P, Connor TJ, Harkin A, Sanchez C, Kelly JP, Leonard BE. Varying responses to the rat forced-swim test under diurnal and nocturnal conditions. Physiology & Behavior. 69: 531-9. PMID 10913793 DOI: 10.1016/S0031-9384(00)00213-4 |
0.492 |
|
2000 |
Connor TJ, Kelliher P, Shen Y, Harkin A, Kelly JP, Leonard BE. Effect of subchronic antidepressant treatments on behavioral, neurochemical, and endocrine changes in the forced-swim test. Pharmacology, Biochemistry, and Behavior. 65: 591-7. PMID 10764911 DOI: 10.1016/S0091-3057(99)00192-6 |
0.526 |
|
2000 |
Connor TJ, Kelly JP, Leonard BE. An assessment of the acute effects of the serotonin releasers methylenedioxymethamphetamine, methylenedioxyamphetamine and fenfluramine on immunity in rats. Immunopharmacology. 46: 223-35. PMID 10741902 DOI: 10.1016/S0162-3109(99)00180-0 |
0.556 |
|
2000 |
Connor TJ, Harkin A, Kelly JP, Leonard BE. Olfactory bulbectomy provokes a suppression of interleukin-1beta and tumour necrosis factor-alpha production in response to an in vivo challenge with lipopolysaccharide: effect of chronic desipramine treatment. Neuroimmunomodulation. 7: 27-35. PMID 10601816 DOI: 10.1159/000026417 |
0.579 |
|
2000 |
Kelly JP, Connor TJ, Nolan Y, Shen Y, Leonard BE. Differential effect of chronic antidepressant treatments on lipopolysaccharide-induced depressive-like behavioural symptoms and the pro-/anti-inflammatory cytokine balance European Neuropsychopharmacology. 10: 278-279. DOI: 10.1016/S0924-977X(00)80278-3 |
0.516 |
|
1999 |
Dredge K, Connor TJ, Kelly JP, Leonard BE. Differential effect of a single high dose of the tricyclic antidepressant imipramine on interleukin-1beta and tumor necrosis factor-alpha secretion following an in vivo lipopolysaccharide challenge in rats. International Journal of Immunopharmacology. 21: 663-73. PMID 12609461 DOI: 10.1016/S0192-0561(99)00042-9 |
0.582 |
|
1999 |
Shen Y, Connor TJ, Nolan Y, Kelly JP, Leonard BE. Differential effect of chronic antidepressant treatments on lipopolysaccharide-induced depressive-like behavioural symptoms in the rat. Life Sciences. 65: 1773-86. PMID 10576557 DOI: 10.1016/S0024-3205(99)00430-0 |
0.548 |
|
1999 |
Connor TJ, Kelliher P, Harkin A, Kelly JP, Leonard BE. Reboxetine attenuates forced swim test-induced behavioural and neurochemical alterations in the rat. European Journal of Pharmacology. 379: 125-33. PMID 10497898 DOI: 10.1016/S0014-2999(99)00492-6 |
0.517 |
|
1999 |
Connor TJ, Song C, Leonard BE, Anisman H, Merali Z. Stressor-induced alterations in serotonergic activity in an animal model of depression. Neuroreport. 10: 523-8. PMID 10208583 DOI: 10.1097/00001756-199902250-00015 |
0.518 |
|
1999 |
Harkin A, Kelly JP, McNamara M, Connor TJ, Dredge K, Redmond A, Leonard BE. Activity and onset of action of reboxetine and effect of combination with sertraline in an animal model of depression. European Journal of Pharmacology. 364: 123-32. PMID 9932714 DOI: 10.1016/S0014-2999(98)00838-3 |
0.523 |
|
1999 |
Connor TJ, McNamara MG, Kelly JP, Leonard BE. 3,4-Methylenedioxymethamphetamine (MDMA; Ecstasy) administration produces dose-dependent neurochemical, endocrine and immune changes in the rat Human Psychopharmacology. 14: 95-104. DOI: 10.1002/(SICI)1099-1077(199903)14:2<95::AID-HUP72>3.0.CO;2-7 |
0.473 |
|
1999 |
Shen Y, Connor TJ, Kelly JP, Leonard BE. Effects of chronic dietary supplementation with ω3 and ω6 fatty acid rich oils on lipopolysaccharide-induced behavioural responses and interleukin-1β secretion in the rat Medical Science Research. 27: 291-294. |
0.389 |
|
1998 |
Connor TJ, Song C, Leonard BE, Merali Z, Anisman H. An assessment of the effects of central interleukin-1beta, -2, -6, and tumor necrosis factor-alpha administration on some behavioural, neurochemical, endocrine and immune parameters in the rat. Neuroscience. 84: 923-33. PMID 9579794 DOI: 10.1016/S0306-4522(97)00533-2 |
0.552 |
|
1998 |
Connor TJ, McNamara MG, Finn D, Currid A, O'Malley M, Redmond AM, Kelly JP, Leonard BE. Acute 3,4-methylenedioxymethamphetamine(MDMA) administration produces a rapid and sustained suppression of immune function in the rat. Immunopharmacology. 38: 253-60. PMID 9506825 DOI: 10.1016/S0162-3109(97)00084-2 |
0.519 |
|
1998 |
Connor TJ, Leonard BE. Depression, stress and immunological activation: the role of cytokines in depressive disorders. Life Sciences. 62: 583-606. PMID 9472719 DOI: 10.1016/S0024-3205(97)00990-9 |
0.52 |
|
1998 |
Connor TJ, Kelly JP, Leonard BE. Forced swim test-induced endocrine and immune changes in the rat: effect of subacute desipramine treatment. Pharmacology, Biochemistry, and Behavior. 59: 171-7. PMID 9443552 DOI: 10.1016/S0091-3057(97)00316-X |
0.544 |
|
1998 |
Kellihera P, Connor TJ, Sanchez C, Kelly JP, Leonard BE. CIRCADIAN ALTERATIONS IN THE RAT FORCED SWIM TEST Behavioural Pharmacology. 9: S49. DOI: 10.1097/00008877-199808000-00099 |
0.446 |
|
1998 |
Connor TJ, Kelliher P, Shen Y, Harkin A, Kelly JP, Leonard BE. Effect of chronic antidepressant treatment on behavioural, neurochemical and endocrine changes following forced swim test exposure European Neuropsychopharmacology. 8. DOI: 10.1016/S0924-977X(98)80288-5 |
0.463 |
|
1997 |
Connor TJ, Kelly JP, Leonard BE. Forced swim test-induced neurochemical endocrine, and immune changes in the rat. Pharmacology, Biochemistry, and Behavior. 58: 961-7. PMID 9408201 DOI: 10.1016/S0091-3057(97)00028-2 |
0.517 |
|
1997 |
Connor TJ, Kelly JP, Leonard BE. Effect of acute desipramine treatment on immunological parameters in the rat Medical Science Research. 25: 209-211. |
0.379 |
|
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