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John F. Cryan - Publications

Affiliations: 
University College Cork, Cork, County Cork, Ireland 
Area:
Depression, anxiety, drug dependence, stress related disorders, GABAB, behaviour, mGluR
Website:
http://publish.ucc.ie/researchprofiles/C019/jcryan/home

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Year Citation  Score
2019 Gururajan A, van de Wouw M, Boehme M, Becker T, O'Connor R, Bastiaanssen TFS, Moloney GM, Lyte JM, Paula Ventura Silva A, Merckx B, Dinan TG, Cryan JF. Resilience to Chronic Stress Is Associated with Specific Neurobiological, Neuroendocrine and Immune Responses. Brain, Behavior, and Immunity. PMID 31059807 DOI: 10.1016/j.bbi.2019.05.004  1
2019 Chruścicka B, Wallace Fitzsimons SE, Borroto-Escuela DO, Druelle C, Stamou P, Nally K, Dinan TG, Cryan JF, Fuxe K, Schellekens H. Attenuation of Oxytocin and Serotonin 2A Receptor Signalling through Novel Heteroreceptor Formation. Acs Chemical Neuroscience. PMID 31038917 DOI: 10.1021/acschemneuro.8b00665  1
2019 Cryan JF, Dinan TG. Talking about a microbiome revolution. Nature Microbiology. 4: 552-553. PMID 30899109 DOI: 10.1038/s41564-019-0422-9  1
2019 Fülling C, Dinan TG, Cryan JF. Gut Microbe to Brain Signaling: What Happens in Vagus…. Neuron. 101: 998-1002. PMID 30897366 DOI: 10.1016/j.neuron.2019.02.008  1
2019 Clarke G, Sandhu KV, Griffin BT, Dinan TG, Cryan JF, Hyland NP. Gut Reactions: Breaking Down Xenobiotic-Microbiome Interactions. Pharmacological Reviews. 71: 198-224. PMID 30890566 DOI: 10.1124/pr.118.015768  1
2019 Cryan JF, Boehme M, Dinan TG. Is the fountain of youth in the gut microbiome? The Journal of Physiology. PMID 30875099 DOI: 10.1113/JP277784  1
2019 Butler MI, Sandhu K, Cryan JF, Dinan TG. From isoniazid to psychobiotics: the gut microbiome as a new antidepressant target. British Journal of Hospital Medicine (London, England : 2005). 80: 139-145. PMID 30860919 DOI: 10.12968/hmed.2019.80.3.139  1
2019 Cussotto S, Clarke G, Dinan TG, Cryan JF. Psychotropics and the Microbiome: a Chamber of Secrets…. Psychopharmacology. PMID 30806744 DOI: 10.1007/s00213-019-5185-8  1
2019 Butler MI, Cryan JF, Dinan TG. Man and the Microbiome: A New Theory of Everything? Annual Review of Clinical Psychology. PMID 30786244 DOI: 10.1146/annurev-clinpsy-050718-095432  1
2019 Dinan TG, Cryan JF. Gut microbes and depression: Still waiting for Godot. Brain, Behavior, and Immunity. PMID 30771453 DOI: 10.1016/j.bbi.2019.02.007  1
2019 Moloney GM, van Oeffelen WEPA, Ryan FJ, van de Wouw M, Cowan C, Claesson MJ, Schellekens H, Dinan TG, Cryan JF. Differential Gene Expression in the Mesocorticolimbic System of Innately High- and Low-Impulsive Rats. Behavioural Brain Research. PMID 30738103 DOI: 10.1016/j.bbr.2019.01.022  1
2019 Ramos Costa AP, Levone BR, Gururajan A, Moloney G, Hoeller AA, Lino-de-Oliveira C, Dinan TG, O'Leary OF, Monteiro de Lima TC, Cryan JF. Enduring effects of muscarinic receptor activation on adult hippocampal neurogenesis, microRNA expression and behaviour. Behavioural Brain Research. 362: 188-198. PMID 30650342 DOI: 10.1016/j.bbr.2018.12.043  1
2018 O'Leary JD, Hoban AE, Murphy A, O'Leary OF, Cryan JF, Nolan YM. Differential effects of adolescent and adult-initiated exercise on cognition and hippocampal neurogenesis. Hippocampus. PMID 30844139 DOI: 10.1002/hipo.23032  1
2018 Balta JY, Cryan JF, O'Mahony SM. The Antimicrobial Capacity of Embalming Solutions: A Comparative Study. Journal of Applied Microbiology. PMID 30597684 DOI: 10.1111/jam.14191  1
2018 Wallace Fitzsimons SE, Chruścicka B, Druelle C, Stamou P, Nally K, Dinan TG, Cryan JF, Schellekens H. A ghrelin receptor and oxytocin receptor heterocomplex impairs oxytocin mediated signalling. Neuropharmacology. PMID 30582955 DOI: 10.1016/j.neuropharm.2018.12.022  1
2018 Dinan TG, Stanton C, Long-Smith C, Kennedy P, Cryan JF, Cowan CSM, Cenit MC, van der Kamp JW, Sanz Y. Feeding melancholic microbes: MyNewGut recommendations on diet and mood. Clinical Nutrition (Edinburgh, Scotland). PMID 30497694 DOI: 10.1016/j.clnu.2018.11.010  1
2018 Kozareva DA, Foley T, Moloney GM, Cryan JF, Nolan YM. TLX knockdown in the dorsal dentate gyrus of juvenile rats differentially affects adolescent and adult behaviour. Behavioural Brain Research. PMID 30481511 DOI: 10.1016/j.bbr.2018.11.034  1
2018 Hyland NP, Cryan JF. When pharmacology meets the microbiome: new targets for therapeutics? British Journal of Pharmacology. 175: 4401-4403. PMID 30478976 DOI: 10.1111/bph.14502  1
2018 Balta JY, Twomey M, Moloney F, Duggan O, Murphy KP, O'Connor OJ, Cronin M, Cryan JF, Maher MM, O'Mahony SM. A comparison of embalming fluids on the structures and properties of tissue in human cadavers. Anatomia, Histologia, Embryologia. PMID 30450564 DOI: 10.1111/ahe.12412  1
2018 Lucking EF, O'Connor KM, Strain CR, Fouhy F, Bastiaanssen TFS, Burns DP, Golubeva AV, Stanton C, Clarke G, Cryan JF, O'Halloran KD. Chronic intermittent hypoxia disrupts cardiorespiratory homeostasis and gut microbiota composition in adult male guinea-pigs. Ebiomedicine. PMID 30446434 DOI: 10.1016/j.ebiom.2018.11.010  0.88
2018 Dinan TG, Cryan JF. Schizophrenia and the Microbiome: Time to Focus on the Impact of Antipsychotic Treatment on the Gut Microbiota. The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry. 1-7. PMID 30394174 DOI: 10.1080/15622975.2018.1540793  1
2018 Lone M, Vagg T, Theocharopoulos A, Cryan JF, Mckenna JP, Downer EJ, Toulouse A. Development and Assessment of a Three-Dimensional Tooth Morphology Quiz for Dental Students. Anatomical Sciences Education. PMID 30378278 DOI: 10.1002/ase.1815  0.48
2018 Cryan JF, Dinan TG. Decoding the role of the microbiome on amygdala function and social behaviour. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 30341410 DOI: 10.1038/s41386-018-0233-3  1
2018 Howick K, Wallace-Fitzsimons SE, Kandil D, Chruścicka B, Calis M, Murphy E, Murray BA, Fernandez A, Barry KM, Kelly PM, Ryan AM, Cryan JF, Griffin BT, Schellekens H. A Dairy-Derived Ghrelinergic Hydrolysate Modulates Food Intake In Vivo. International Journal of Molecular Sciences. 19. PMID 30223587 DOI: 10.3390/ijms19092780  0.8
2018 Hueston CM, O'Leary JD, Hoban AE, Kozareva DA, Pawley LC, O'Leary OF, Cryan JF, Nolan YM. Chronic interleukin-1β in the dorsal hippocampus impairs behavioural pattern separation. Brain, Behavior, and Immunity. PMID 30217534 DOI: 10.1016/j.bbi.2018.09.015  1
2018 O'Connor RM, McCafferty CP, Bravo JA, Singewald N, Holmes A, Cryan JF. Increased amygdalar metabotropic glutamate receptor 7 mRNA in a genetic mouse model of impaired fear extinction. Psychopharmacology. PMID 30215216 DOI: 10.1007/s00213-018-5031-4  0.96
2018 Scriven M, Dinan TG, Cryan JF, Wall M. Neuropsychiatric Disorders: Influence of Gut Microbe to Brain Signalling. Diseases (Basel, Switzerland). 6. PMID 30200574 DOI: 10.3390/diseases6030078  1
2018 Jadhav KS, Peterson VL, Halfon O, Ahern G, Fouhy F, Stanton C, Dinan TG, Cryan JF, Boutrel B. Gut microbiome correlates with altered striatal dopamine receptor expression in a model of compulsive alcohol seeking. Neuropharmacology. PMID 30172845 DOI: 10.1016/j.neuropharm.2018.08.026  1
2018 Cussotto S, Strain CR, Fouhy F, Strain RG, Peterson VL, Clarke G, Stanton C, Dinan TG, Cryan JF. Differential effects of psychotropic drugs on microbiome composition and gastrointestinal function. Psychopharmacology. PMID 30155748 DOI: 10.1007/s00213-018-5006-5  1
2018 Bastiaanssen TFS, Cowan CSM, Claesson MJ, Dinan TG, Cryan JF. Making Sense of… the Microbiome in Psychiatry. The International Journal of Neuropsychopharmacology. PMID 30099552 DOI: 10.1093/ijnp/pyy067  1
2018 van de Wouw M, Boehme M, Lyte JM, Wiley N, Strain C, O'Sullivan O, Clarke G, Stanton C, Dinan TG, Cryan JF. Short-chain fatty acids: microbial metabolites that alleviate stress-induced brain-gut axis alterations. The Journal of Physiology. PMID 30066368 DOI: 10.1113/JP276431  1
2018 Codagnone MG, Spichak S, O'Mahony SM, O'Leary OF, Clarke G, Stanton C, Dinan TG, Cryan JF. Programming Bugs: Microbiota and the Developmental Origins of Brain Health and Disease. Biological Psychiatry. PMID 30064690 DOI: 10.1016/j.biopsych.2018.06.014  1
2018 Ramirez VT, van Oeffelen WEPA, Torres-Fuentes C, Chruścicka B, Druelle C, Golubeva AV, van de Wouw M, Dinan TG, Cryan JF, Schellekens H. Differential functional selectivity and downstream signaling bias of ghrelin receptor antagonists and inverse agonists. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201800655R. PMID 30020830 DOI: 10.1096/fj.201800655R  1
2018 Sarkar A, Harty S, Lehto SM, Moeller AH, Dinan TG, Dunbar RIM, Cryan JF, Burnet PWJ. The Microbiome in Psychology and Cognitive Neuroscience. Trends in Cognitive Sciences. PMID 29907531 DOI: 10.1016/j.tics.2018.04.006  1
2018 Cryan JF, Clarke G, Dinan TG, Schellekens H. A Microbial Drugstore for Motility. Cell Host & Microbe. 23: 691-692. PMID 29902430 DOI: 10.1016/j.chom.2018.05.020  1
2018 Stilling RM, Moloney GM, Ryan FJ, Hoban AE, Bastiaanssen T, Shanahan F, Clarke G, Claesson MJ, Dinan TG, Cryan JF. Social interaction-induced activation of RNA splicing in the amygdala of microbiome-deficient mice. Elife. 7. PMID 29809134 DOI: 10.7554/eLife.33070  1
2018 O'Leary JD, Hoban AE, Cryan JF, O'Leary OF, Nolan YM. Differential effects of adolescent and adult-initiated voluntary exercise on context and cued fear conditioning. Neuropharmacology. PMID 29793890 DOI: 10.1016/j.neuropharm.2018.05.007  1
2018 Jacobson LH, Vlachou S, Slattery DA, Li X, Cryan JF. The Gamma-Aminobutyric Acid B Receptor in Depression and Reward. Biological Psychiatry. 83: 963-976. PMID 29759132 DOI: 10.1016/j.biopsych.2018.02.006  1
2018 Cussotto S, Sandhu KV, Dinan TG, Cryan JF. The Neuroendocrinology of the Microbiota-Gut-Brain Axis: A Behavioural Perspective. Frontiers in Neuroendocrinology. PMID 29753796 DOI: 10.1016/j.yfrne.2018.04.002  1
2018 Moloney F, Twomey M, Fama D, Balta JY, James K, Kavanagh RG, Moore N, Murphy MJ, O'Mahony SM, Maher MM, Cryan JF, O'Connor OJ. Determination of a suitable low-dose abdominopelvic CT protocol using model-based iterative reconstruction through cadaveric study. Journal of Medical Imaging and Radiation Oncology. PMID 29656596 DOI: 10.1111/1754-9485.12733  1
2018 O'Leary JD, O'Leary OF, Cryan JF, Nolan YM. A low-cost touchscreen operant chamber using a Raspberry Pi™. Behavior Research Methods. PMID 29520633 DOI: 10.3758/s13428-018-1030-y  1
2018 Léime CSÓ, Hoban AE, Hueston CM, Stilling R, Moloney G, Cryan JF, Nolan YM. The orphan nuclear receptor TLX regulates hippocampal transcriptome changes induced by IL-1β. Brain, Behavior, and Immunity. PMID 29518529 DOI: 10.1016/j.bbi.2018.03.006  1
2018 O'Halloran F, Bruen C, McGrath B, Schellekens H, Murray B, Cryan JF, Kelly AL, McSweeney PLH, Giblin L. A casein hydrolysate increases GLP-1 secretion and reduces food intake. Food Chemistry. 252: 303-310. PMID 29478546 DOI: 10.1016/j.foodchem.2018.01.107  0.8
2018 Morais LH, Felice D, Golubeva AV, Moloney G, Dinan TG, Cryan JF. Strain differences in the susceptibility to the gut-brain axis and neurobehavioural alterations induced by maternal immune activation in mice. Behavioural Pharmacology. PMID 29462110 DOI: 10.1097/FBP.0000000000000374  1
2018 O'Leary OF, Ogbonnaya ES, Felice D, Levone BR, C Conroy L, Fitzgerald P, Bravo JA, Forsythe P, Bienenstock J, Dinan TG, Cryan JF. The vagus nerve modulates BDNF expression and neurogenesis in the hippocampus. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. PMID 29426666 DOI: 10.1016/j.euroneuro.2017.12.004  1
2018 Gite S, Ross RP, Kirke D, Guihéneuf F, Aussant J, Stengel DB, Dinan TG, Cryan JF, Stanton C. Nutraceuticals to promote neuronal plasticity in response to corticosterone-induced stress in human neuroblastoma cells. Nutritional Neuroscience. 1-18. PMID 29378496 DOI: 10.1080/1028415X.2017.1418728  1
2018 Donovan MD, Abduljalil K, Cryan JF, Boylan GB, Griffin BT. Application of a Physiologically-Based Pharmacokinetic Model for the Prediction of Bumetanide Plasma and Brain Concentrations in the Neonate. Biopharmaceutics & Drug Disposition. PMID 29319897 DOI: 10.1002/bdd.2119  0.72
2018 Dinan TG, Cryan JF, Stanton C. Gut Microbes and Brain Development Have Black Box Connectivity. Biological Psychiatry. 83: 97-99. PMID 29223221 DOI: 10.1016/j.biopsych.2017.11.005  1
2017 Bambury A, Sandhu K, Cryan JF, Dinan TG. Finding the needle in the haystack: systematic identification of psychobiotics. British Journal of Pharmacology. PMID 29243233 DOI: 10.1111/bph.14127  1
2017 Howick K, Alam R, Chruscicka B, Kandil D, Fitzpatrick D, Ryan AM, Cryan JF, Schellekens H, Griffin BT. Sustained-release multiparticulates for oral delivery of a novel peptidic ghrelin agonist: Formulation design and in vitro characterization. International Journal of Pharmaceutics. 536: 63-72. PMID 29175643 DOI: 10.1016/j.ijpharm.2017.11.051  0.8
2017 Robertson RC, Seira Oriach C, Murphy K, Moloney GM, Cryan JF, Dinan TG, Ross RP, Stanton C. Deficiency of essential dietary n-3 PUFA disrupts the caecal microbiome and metabolome in mice. The British Journal of Nutrition. 118: 959-970. PMID 29173237 DOI: 10.1017/S0007114517002999  1
2017 McVey Neufeld KA, O'Mahony SM, Hoban AE, Waworuntu RV, Berg BM, Dinan TG, Cryan JF. Neurobehavioural effects of Lactobacillus rhamnosus GG alone and in combination with prebiotics polydextrose and galactooligosaccharide in male rats exposed to early-life stress. Nutritional Neuroscience. 1-10. PMID 29173065 DOI: 10.1080/1028415X.2017.1397875  1
2017 Cowan CSM, Hoban AE, Ventura-Silva AP, Dinan TG, Clarke G, Cryan JF. Gutsy Moves: The Amygdala as a Critical Node in Microbiota to Brain Signaling. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. PMID 29148060 DOI: 10.1002/bies.201700172  1
2017 Lach G, Schellekens H, Dinan TG, Cryan JF. Anxiety, Depression, and the Microbiome: A Role for Gut Peptides. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. PMID 29134359 DOI: 10.1007/s13311-017-0585-0  1
2017 Doherty FD, O'Mahony SM, Peterson VL, O'Sullivan O, Crispie F, Cotter PD, Wigmore P, King MV, Cryan JF, Fone KCF. Post-Weaning Social Isolation of Rats Leads to Long-term Disruption of the Gut Microbiota-Immune-Brain Axis. Brain, Behavior, and Immunity. PMID 29104061 DOI: 10.1016/j.bbi.2017.10.024  1
2017 Ryan PM, Patterson E, Kent RM, Stack H, O'Connor PM, Murphy K, Peterson VL, Mandal R, Wishart DS, Dinan TG, Cryan JF, Seeley RJ, Stanton C, Ross RP. Recombinant Incretin-Secreting Microbe Improves Metabolic Dysfunction in High-Fat Diet Fed Rodents. Scientific Reports. 7: 13523. PMID 29051554 DOI: 10.1038/s41598-017-14010-x  1
2017 Kozareva DA, O'Leary OF, Cryan JF, Nolan YM. Deletion of Tlx and social isolation impairs exercise-induced neurogenesis in the adolescent hippocampus. Hippocampus. PMID 28972669 DOI: 10.1002/hipo.22805  1
2017 Ó'Léime CS, Kozareva DA, Hoban AE, Long-Smith CM, Cryan JF, Nolan YM. TLX is an intrinsic regulator of the negative effects of IL-1β on proliferating hippocampal neural progenitor cells. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 28970252 DOI: 10.1096/fj.201700495R  1
2017 Kelly JR, Minuto C, Cryan JF, Clarke G, Dinan TG. Cross Talk: The Microbiota and Neurodevelopmental Disorders. Frontiers in Neuroscience. 11: 490. PMID 28966571 DOI: 10.3389/fnins.2017.00490  1
2017 Golubeva AV, Joyce SA, Moloney G, Burokas A, Sherwin E, Arboleya S, Flynn I, Khochanskiy D, Moya-Pérez A, Peterson V, Rea K, Murphy K, Makarova O, Buravkov S, Hyland NP, ... ... Cryan JF, et al. Microbiota-related Changes in Bile Acid & Tryptophan Metabolism are Associated with Gastrointestinal Dysfunction in a Mouse Model of Autism. Ebiomedicine. PMID 28965876 DOI: 10.1016/j.ebiom.2017.09.020  1
2017 Hueston CM, Cryan JF, Nolan YM. Adolescent Social Isolation Stress Unmasks the Combined Effects of: Adolescent Exercise and Adult Inflammation on Hippocampal Neurogenesis and Behaviour. Neuroscience. PMID 28939260 DOI: 10.1016/j.neuroscience.2017.09.020  1
2017 Torres-Fuentes C, Schellekens H, Dinan TG, Cryan JF. The microbiota-gut-brain axis in obesity. The Lancet. Gastroenterology & Hepatology. PMID 28844808 DOI: 10.1016/S2468-1253(17)30147-4  1
2017 Kozareva DA, Hueston CM, Ó'Léime CS, Crotty S, Dockery P, Cryan JF, Nolan YM. Absence of the neurogenesis-dependent nuclear receptor TLX induces inflammation in the hippocampus. Journal of Neuroimmunology. PMID 28844503 DOI: 10.1016/j.jneuroim.2017.08.008  1
2017 Hoban AE, Stilling RM, M Moloney G, Moloney RD, Shanahan F, Dinan TG, Cryan JF, Clarke G. Microbial regulation of microRNA expression in the amygdala and prefrontal cortex. Microbiome. 5: 102. PMID 28838324 DOI: 10.1186/s40168-017-0321-3  1
2017 Dinan TG, Cryan JF. Brain-gut-microbiota axis and mental health. Psychosomatic Medicine. PMID 28806201 DOI: 10.1097/PSY.0000000000000519  1
2017 Allen AP, Dinan TG, Clarke G, Cryan JF. A psychology of the human brain-gut-microbiome axis. Social and Personality Psychology Compass. 11: e12309. PMID 28804508 DOI: 10.1111/spc3.12309  1
2017 Sherwin E, Dinan TG, Cryan JF. Recent developments in understanding the role of the gut microbiota in brain health and disease. Annals of the New York Academy of Sciences. PMID 28768369 DOI: 10.1111/nyas.13416  1
2017 O'Léime CS, Cryan JF, Nolan YM. Nuclear deterrents: Intrinsic regulators of IL-1β-induced effects on hippocampal neurogenesis. Brain, Behavior, and Immunity. PMID 28751020 DOI: 10.1016/j.bbi.2017.07.153  1
2017 Rea K, Dinan TG, Cryan JF. The Brain-Gut Axis Contributes to Neuroprogression in Stress-Related Disorders. Modern Trends in Pharmacopsychiatry. 31: 152-161. PMID 28738330 DOI: 10.1159/000470813  1
2017 Moloney GM, O'Leary OF, Salvo-Romero E, Desbonnet L, Shanahan F, Dinan TG, Clarke G, Cryan JF. Microbial regulation of hippocampal miRNA expression: Implications for transcription of kynurenine pathway enzymes. Behavioural Brain Research. PMID 28736331 DOI: 10.1016/j.bbr.2017.07.026  1
2017 Pizzo R, O'Leary OF, Cryan JF. Elucidation of the neural circuits activated by a GABAB receptor positive modulator: Relevance to anxiety. Neuropharmacology. PMID 28734870 DOI: 10.1016/j.neuropharm.2017.07.021  1
2017 Dinan TG, Cryan JF. Gut Feelings on Parkinson's and Depression. Cerebrum : the Dana Forum On Brain Science. 2017. PMID 28698775  1
2017 Luczynski P, Tramullas M, Viola M, Shanahan F, Clarke G, O'Mahony S, Dinan TG, Cryan JF. Microbiota regulates visceral pain in the mouse. Elife. 6. PMID 28629511 DOI: 10.7554/eLife.25887  1
2017 Javaid MA, Chakraborty S, Cryan JF, Schellekens H, Toulouse A. Understanding neurophobia: Reasons behind impaired understanding and learning of neuroanatomy in cross-disciplinary healthcare students. Anatomical Sciences Education. PMID 28628732 DOI: 10.1002/ase.1711  0.8
2017 Allen AP, Clarke G, Cryan JF, Quigley EMM, Dinan TG. Bifidobacterium infantis 35624 and other probiotics in the management of irritable bowel syndrome. Strain specificity, symptoms and mechanisms. Current Medical Research and Opinion. 1-8. PMID 28436237 DOI: 10.1080/03007995.2017.1322571  1
2017 Curran EA, Kenny LC, Dalman C, Kearney PM, Cryan JF, Dinan TG, Khashan AS. Birth by caesarean section and school performance in Swedish adolescents- a population-based study. Bmc Pregnancy and Childbirth. 17: 121. PMID 28415966 DOI: 10.1186/s12884-017-1304-x  1
2017 Moya-Pérez A, Luczynski P, Renes IB, Wang S, Borre Y, Anthony Ryan C, Knol J, Stanton C, Dinan TG, Cryan JF. Intervention strategies for cesarean section-induced alterations in the microbiota-gut-brain axis. Nutrition Reviews. PMID 28379454 DOI: 10.1093/nutrit/nuw069  1
2017 Lone M, McKenna JP, Balta JY, O'Mahony SM, Cryan JF, Downer EJ, Toulouse A. Assessment of Thiel-Embalmed Cadavers as a Teaching Tool for Oral Anatomy and Local Anesthesia. Journal of Dental Education. 81: 420-426. PMID 28365606 DOI: 10.21815/JDE.016.012  1
2017 van de Wouw M, Schellekens H, Dinan TG, Cryan JF. Microbiota-Gut-Brain Axis: Modulator of Host Metabolism and Appetite. The Journal of Nutrition. PMID 28356427 DOI: 10.3945/jn.116.240481  1
2017 Cussotto S, Cryan JF, O'Leary OF. The hippocampus and dorsal raphe nucleus are key brain areas associated with the antidepressant effects of lithium augmentation of desipramine. Neuroscience Letters. PMID 28351776 DOI: 10.1016/j.neulet.2017.03.040  1
2017 Nilaweera KN, Cabrera-Rubio R, Speakman JR, O' Connor PM, McAuliffe A, Guinane CM, Lawton E, Crispie F, Aguilera M, Stanley M, Boscaini S, Joyce S, Melgar S, Cryan JF, Cotter PD. Whey protein-effects on energy balance link the intestinal mechanisms of energy absorption with adiposity and hypothalamic neuropeptide gene expression. American Journal of Physiology. Endocrinology and Metabolism. ajpendo.00356.2016. PMID 28325732 DOI: 10.1152/ajpendo.00356.2016  0.48
2017 McCarthy T, Bruen C, O'Halloran F, Schellekens H, Kilcawley K, Cryan JF, Giblin L. Aroma compound diacetyl suppresses glucagon-like peptide-1 production and secretion in STC-1 cells. Food Chemistry. 228: 35-42. PMID 28317734 DOI: 10.1016/j.foodchem.2017.01.104  0.8
2017 Patterson E, Wall R, Lisai S, Ross RP, Dinan TG, Cryan JF, Fitzgerald GF, Banni S, Quigley EM, Shanahan F, Stanton C. Bifidobacterium breve with α-linolenic acid alters the composition, distribution and transcription factor activity associated with metabolism and absorption of fat. Scientific Reports. 7: 43300. PMID 28265110 DOI: 10.1038/srep43300  1
2017 Burokas A, Arboleya S, Moloney RD, Peterson VL, Murphy K, Clarke G, Stanton C, Dinan TG, Cryan JF. Targeting the Microbiota-Gut-Brain Axis: Prebiotics Have Anxiolytic and Antidepressant-like Effects and Reverse the Impact of Chronic Stress in Mice. Biological Psychiatry. PMID 28242013 DOI: 10.1016/j.biopsych.2016.12.031  1
2017 O'Mahony SM, Clarke G, Dinan TG, Cryan JF. Irritable Bowel Syndrome and Stress-Related Psychiatric Co-morbidities: Focus on Early Life Stress. Handbook of Experimental Pharmacology. PMID 28233180 DOI: 10.1007/164_2016_128  1
2017 Allen AP, Kennedy PJ, Dockray S, Cryan JF, Dinan TG, Clarke G. The Trier Social Stress Test: Principles and practice. Neurobiology of Stress. 6: 113-126. PMID 28229114 DOI: 10.1016/j.ynstr.2016.11.001  1
2017 Scott KA, Ida M, Peterson VL, Prenderville JA, Moloney GM, Izumo T, Murphy K, Murphy A, Ross RP, Stanton C, Dinan TG, Cryan JF. Revisiting Metchnikoff: Age-related Alterations in Microbiota-Gut-Brain Axis in the Mouse. Brain, Behavior, and Immunity. PMID 28179108 DOI: 10.1016/j.bbi.2017.02.004  1
2017 Dinan TG, Cryan JF. The Microbiome-Gut-Brain Axis in Health and Disease. Gastroenterology Clinics of North America. 46: 77-89. PMID 28164854 DOI: 10.1016/j.gtc.2016.09.007  1
2017 Peterson VL, Jury NJ, Cabrera-Rubio R, Draper LA, Crispie F, Cotter PD, Dinan TG, Holmes A, Cryan JF. Drunk Bugs: Chronic Vapour Alcohol Exposure Induces Marked Changes in the Gut Microbiome in Mice. Behavioural Brain Research. PMID 28161446 DOI: 10.1016/j.bbr.2017.01.049  1
2017 Howick K, Griffin BT, Cryan JF, Schellekens H. From Belly to Brain: Targeting the Ghrelin Receptor in Appetite and Food Intake Regulation. International Journal of Molecular Sciences. 18. PMID 28134808 DOI: 10.3390/ijms18020273  0.8
2017 Jacobson LH, Hoyer D, Fehlmann D, Bettler B, Kaupmann K, Cryan JF. Blunted 5-HT1A receptor-mediated responses and antidepressant-like behavior in mice lacking the GABAB1a but not GABAB1b subunit isoforms. Psychopharmacology. PMID 28070618 DOI: 10.1007/s00213-016-4521-5  0.96
2017 Dinan TG, Cryan JF. Gut-brain axis in 2016: Brain-gut-microbiota axis - mood, metabolism and behaviour. Nature Reviews. Gastroenterology & Hepatology. PMID 28053341 DOI: 10.1038/nrgastro.2016.200  1
2016 Rea K, O'Mahony SM, Dinan TG, Cryan JF. The Role of the Gastrointestinal Microbiota in Visceral Pain. Handbook of Experimental Pharmacology. PMID 28035535 DOI: 10.1007/164_2016_115  1
2016 Allen AP, Curran EA, Duggan Á, Cryan JF, Chorcoráin AN, Dinan TG, Molloy DW, Kearney PM, Clarke G. A systematic review of the psychobiological burden of informal caregiving for patients with dementia: Focus on cognitive and biological markers of chronic stress. Neuroscience and Biobehavioral Reviews. PMID 27986469 DOI: 10.1016/j.neubiorev.2016.12.006  1
2016 Rea K, Dinan TG, Cryan JF. The microbiome: A key regulator of stress and neuroinflammation. Neurobiology of Stress. 4: 23-33. PMID 27981187 DOI: 10.1016/j.ynstr.2016.03.001  1
2016 O' Mahony SM, Dinan TG, Cryan JF. The Gut Microbiota as a Key Regulator of Visceral Pain. Pain. PMID 27918315 DOI: 10.1097/j.pain.0000000000000779  1
2016 Kelly JR, Allen AP, Temko A, Hutch W, Kennedy PJ, Farid N, Murphy E, Boylan G, Bienenstock J, Cryan JF, Clarke G, Dinan TG. Lost in Translation? The potential psychobiotic Lactobacillus rhamnosus (JB-1) fails to modulate stress or cognitive performance in healthy male subjects. Brain, Behavior, and Immunity. PMID 27865949 DOI: 10.1016/j.bbi.2016.11.018  1
2016 Sandhu KV, Sherwin E, Schellekens H, Stanton C, Dinan TG, Cryan JF. Feeding the microbiota-gut-brain axis: diet, microbiome, and neuropsychiatry. Translational Research : the Journal of Laboratory and Clinical Medicine. PMID 27832936 DOI: 10.1016/j.trsl.2016.10.002  1
2016 O'Connor RM, Gururajan A, Dinan TG, Kenny PJ, Cryan JF. All Roads Lead to the miRNome: miRNAs Have a Central Role in the Molecular Pathophysiology of Psychiatric Disorders. Trends in Pharmacological Sciences. PMID 27832923 DOI: 10.1016/j.tips.2016.10.004  1
2016 Theis KR, Dheilly NM, Klassen JL, Brucker RM, Baines JF, Bosch TC, Cryan JF, Gilbert SF, Goodnight CJ, Lloyd EA, Sapp J, Vandenkoornhuyse P, Zilber-Rosenberg I, Rosenberg E, Bordenstein SR. Getting the Hologenome Concept Right: an Eco-Evolutionary Framework for Hosts and Their Microbiomes. Msystems. 1. PMID 27822520 DOI: 10.1128/mSystems.00028-16  0.72
2016 Cryan JF, Kenny PJ. Obituary: Athina Markou PhD (1961-2015). Neuropharmacology. PMID 27793770 DOI: 10.1016/j.neuropharm.2016.10.023  0.96
2016 Sarkar A, Lehto SM, Harty S, Dinan TG, Cryan JF, Burnet PW. Psychobiotics and the Manipulation of Bacteria-Gut-Brain Signals. Trends in Neurosciences. PMID 27793434 DOI: 10.1016/j.tins.2016.09.002  1
2016 O'Leary JD, O'Leary OF, Cryan JF, Nolan YM. Regulation of behaviour by the nuclear receptor TLX. Genes, Brain, and Behavior. PMID 27790850 DOI: 10.1111/gbb.12357  1
2016 Dinan TG, Cryan JF. Gut Instincts: microbiota as a key regulator of brain development, ageing and neurodegeneration. The Journal of Physiology. PMID 27641441 DOI: 10.1113/JP273106  1
2016 Shaban H, O'Connor R, Ovsepian SV, Dinan TG, Cryan JF, Schellekens H. Electrophysiological approaches to unravel the neurobiological basis of appetite and satiety: use of the multielectrode array as a screening strategy. Drug Discovery Today. PMID 27634341 DOI: 10.1016/j.drudis.2016.09.003  1
2016 O'Tuathaigh CM, Fumagalli F, Desbonnet L, Perez-Branguli F, Moloney G, Loftus S, O'Leary C, Petit E, Cox R, Tighe O, Clarke G, Lai D, Harvey RP, Cryan JF, Mitchell KJ, et al. Epistatic and Independent Effects on Schizophrenia-Related Phenotypes Following Co-disruption of the Risk Factors Neuregulin-1 × DISC1. Schizophrenia Bulletin. PMID 27613806 DOI: 10.1093/schbul/sbw120  1
2016 Pusceddu MM, Kelly P, Stanton C, Cryan JF, Dinan TG. N-3 Polyunsaturated Fatty Acids Through the Lifespan: Implication for Psychopathology. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). PMID 27608809 DOI: 10.1093/ijnp/pyw078  1
2016 Stilling RM, Cryan JF. Host response: A trigger for neurodegeneration? Nature Microbiology. 1: 16129. PMID 27573123 DOI: 10.1038/nmicrobiol.2016.129  1
2016 Zhdanov AV, Okkelman IA, Golubeva AV, Doerr B, Hyland NP, Melgar S, Shanahan F, Cryan JF, Papkovsky DB. Quantitative analysis of mucosal oxygenation using ex vivo imaging of healthy and inflamed mammalian colon tissue. Cellular and Molecular Life Sciences : Cmls. PMID 27510419 DOI: 10.1007/s00018-016-2323-x  1
2016 Kelly JR, Borre Y, O' Brien C, Patterson E, El Aidy S, Deane J, Kennedy PJ, Beers S, Scott K, Moloney G, Hoban AE, Scott L, Fitzgerald P, Ross P, Stanton C, ... ... Cryan JF, et al. Transferring the blues: Depression-associated gut microbiota induces neurobehavioural changes in the rat. Journal of Psychiatric Research. 82: 109-118. PMID 27491067 DOI: 10.1016/j.jpsychires.2016.07.019  1
2016 Gururajan A, Naughton ME, Scott KA, O'Connor RM, Moloney G, Clarke G, Dowling J, Walsh A, Ismail F, Shorten G, Scott L, McLoughlin DM, Cryan JF, Dinan TG. MicroRNAs as biomarkers for major depression: a role for let-7b and let-7c. Translational Psychiatry. 6: e862. PMID 27483380 DOI: 10.1038/tp.2016.131  1
2016 Sajjad J, Felice VD, Golubeva AV, Cryan JF, O'Mahony SM. Sex-dependent activity of the spinal excitatory amino acid transporter: Role of estrous cycle. Neuroscience. PMID 27471194 DOI: 10.1016/j.neuroscience.2016.07.036  1
2016 Moloney RD, Sajjad J, Foley T, Felice VD, Dinan TG, Cryan JF, O'Mahony SM. Estrous cycle influences excitatory amino acid transport and visceral pain sensitivity in the rat: effects of early-life stress. Biology of Sex Differences. 7: 33. PMID 27429736 DOI: 10.1186/s13293-016-0086-6  1
2016 Robertson RC, Oriach CS, Murphy K, Moloney GM, Cryan JF, Dinan TG, Paul Ross R, Stanton C. Omega-3 polyunsaturated fatty acids critically regulate behaviour and gut microbiota development in adolescence and adulthood. Brain, Behavior, and Immunity. PMID 27423492 DOI: 10.1016/j.bbi.2016.07.145  1
2016 Sherwin E, Sandhu KV, Dinan TG, Cryan JF. May the Force Be With You: The Light and Dark Sides of the Microbiota-Gut-Brain Axis in Neuropsychiatry. Cns Drugs. PMID 27417321 DOI: 10.1007/s40263-016-0370-3  1
2016 Borrelli L, Aceto S, Agnisola C, De Paolo S, Dipineto L, Stilling RM, Dinan TG, Cryan JF, Menna LF, Fioretti A. Probiotic modulation of the microbiota-gut-brain axis and behaviour in zebrafish. Scientific Reports. 6: 30046. PMID 27416816 DOI: 10.1038/srep30046  1
2016 Kennedy PJ, Cryan JF, Dinan TG, Clarke G. Kynurenine pathway metabolism and the microbiota-gut-brain axis. Neuropharmacology. PMID 27392632 DOI: 10.1016/j.neuropharm.2016.07.002  1
2016 Balta JY, Cronin M, Cryan JF, O'Mahony SM. The utility of cadaver-based approaches for the teaching of human anatomy: A survey of British and Irish anatomy teachers. Anatomical Sciences Education. PMID 27352048 DOI: 10.1002/ase.1629  0.64
2016 Stilling RM, van de Wouw M, Clarke G, Stanton C, Dinan Tg TG, Cryan JF. The neuropharmacology of butyrate: The bread and butter of the microbiota-gut-brain axis? Neurochemistry International. PMID 27346602 DOI: 10.1016/j.neuint.2016.06.011  1
2016 Hyland NP, Cryan JF. Microbe-host interactions: Influence of the gut microbiota on the enteric nervous system. Developmental Biology. PMID 27343895 DOI: 10.1016/j.ydbio.2016.06.027  1
2016 Dinan TG, Cryan JF. Microbes, Immunity and Behaviour: Psychoneuroimmunology Meets the Microbiome. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 27319972 DOI: 10.1038/npp.2016.103  1
2016 Neufeld KM, Luczynski P, Oriach CS, Dinan TG, Cryan JF. What's bugging your teen?-The microbiota and adolescent mental health. Neuroscience and Biobehavioral Reviews. PMID 27287940 DOI: 10.1016/j.neubiorev.2016.06.005  1
2016 Straley ME, Van Oeffelen W, Theze S, Sullivan AM, O'Mahony SM, Cryan JF, O'Keeffe GW. Distinct alterations in motor & reward seeking behavior are dependent on the gestational age of exposure to LPS-induced maternal immune activation. Brain, Behavior, and Immunity. PMID 27266391 DOI: 10.1016/j.bbi.2016.06.002  1
2016 Luczynski P, Whelan SO, O'Sullivan C, Clarke G, Shanahan F, Dinan TG, Cryan JF. Adult microbiota-deficient mice have distinct dendritic morphological changes: differential effects in the amygdala and hippocampus. The European Journal of Neuroscience. PMID 27256072 DOI: 10.1111/ejn.13291  1
2016 McVey Neufeld KA, Luczynski P, Dinan TG, Cryan JF. Reframing the Teenage Wasteland: Adolescent Microbiota-Gut-Brain Axis. Canadian Journal of Psychiatry. Revue Canadienne De Psychiatrie. 61: 214-21. PMID 27254413 DOI: 10.1177/0706743716635536  1
2016 Cryan JF. Stress and the Microbiota-Gut-Brain Axis: An Evolving Concept in Psychiatry. Canadian Journal of Psychiatry. Revue Canadienne De Psychiatrie. 61: 201-3. PMID 27254411 DOI: 10.1177/0706743716635538  1
2016 Tramullas M, Finger BC, Dinan TG, Cryan JF. Obesity Takes Its Toll on Visceral Pain: High-Fat Diet Induces Toll-Like Receptor 4-Dependent Visceral Hypersensitivity. Plos One. 11: e0155367. PMID 27159520 DOI: 10.1371/journal.pone.0155367  1
2016 Curran EA, Khashan AS, Dalman C, Kenny LC, Cryan JF, Dinan TG, Kearney PM. Obstetric mode of delivery and attention-deficit/hyperactivity disorder: a sibling-matched study. International Journal of Epidemiology. PMID 27063604 DOI: 10.1093/ije/dyw001  1
2016 Dinan TG, Cryan JF. Mood by microbe: towards clinical translation. Genome Medicine. 8: 36. PMID 27048547 DOI: 10.1186/s13073-016-0292-1  1
2016 Hoban AE, Stilling RM, Ryan FJ, Shanahan F, Dinan TG, Claesson MJ, Clarke G, Cryan JF. Regulation of prefrontal cortex myelination by the microbiota. Translational Psychiatry. 6: e774. PMID 27045844 DOI: 10.1038/tp.2016.42  1
2016 Marques TM, Patterson E, Wall R, O'Sullivan O, Fitzgerald GF, Cotter PD, Dinan TG, Cryan JF, Ross RP, Stanton C. Influence of GABA and GABA-producing Lactobacillus brevis DPC 6108 on the development of diabetes in a streptozotocin rat model. Beneficial Microbes. 1-12. PMID 27013462 DOI: 10.3920/BM2015.0154  1
2016 Kelly JR, Clarke G, Cryan JF, Dinan TG. Brain-gut-microbiota axis: challenges for translation in psychiatry. Annals of Epidemiology. PMID 27005587 DOI: 10.1016/j.annepidem.2016.02.008  1
2016 O'Leary JD, Kozareva DA, Hueston CM, O'Leary OF, Cryan JF, Nolan YM. The nuclear receptor Tlx regulates motor, cognitive and anxiety-related behaviours during adolescence and adulthood. Behavioural Brain Research. PMID 26970576 DOI: 10.1016/j.bbr.2016.03.022  0.48
2016 Donovan MD, Griffin BT, Kharoshankaya L, Cryan JF, Boylan GB. Pharmacotherapy for Neonatal Seizures: Current Knowledge and Future Perspectives. Drugs. PMID 26943929 DOI: 10.1007/s40265-016-0554-7  1
2016 Luczynski P, McVey Neufeld KA, Seira Oriach C, Clarke G, Dinan TG, Cryan JF. Growing up in a Bubble: Using Germ-Free Animals to Assess the Influence of the Gut Microbiota on Brain and Behaviour. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). PMID 26912607 DOI: 10.1093/ijnp/pyw020  1
2016 Patterson E, Ryan PM, Cryan JF, Dinan TG, Ross RP, Fitzgerald GF, Stanton C. Gut microbiota, obesity and diabetes. Postgraduate Medical Journal. PMID 26912499 DOI: 10.1136/postgradmedj-2015-133285  0.4
2016 Gururajan A, Clarke G, Dinan TG, Cryan JF. Molecular biomarkers of depression. Neuroscience and Biobehavioral Reviews. PMID 26906761 DOI: 10.1016/j.neubiorev.2016.02.011  1
2016 Crowley T, Cryan JF, Downer EJ, O'Leary OF. Inhibiting Neuroinflammation: The Role and Therapeutic Potential of Gaba in Neuro-Immune Interactions. Brain, Behavior, and Immunity. PMID 26851553 DOI: 10.1016/j.bbi.2016.02.001  1
2016 Sherwin E, Rea K, Dinan TG, Cryan JF. A gut (microbiome) feeling about the brain. Current Opinion in Gastroenterology. PMID 26760398 DOI: 10.1097/MOG.0000000000000244  0.4
2016 El Aidy S, Stilling R, Dinan TG, Cryan JF. Microbiome to Brain: Unravelling the Multidirectional Axes of Communication. Advances in Experimental Medicine and Biology. 874: 301-36. PMID 26589226 DOI: 10.1007/978-3-319-20215-0_15  1
2016 Oriach CS, Robertson RC, Stanton C, Cryan JF, Dinan TG. Food for thought: The role of nutrition in the microbiota-gut-brain axis Clinical Nutrition Experimental. 6: 25-38. DOI: 10.1016/j.yclnex.2016.01.003  1
2015 Levone BR, Cryan JF, O'Leary OF. Role of adult hippocampal neurogenesis in stress resilience. Neurobiology of Stress. 1: 147-55. PMID 27589664 DOI: 10.1016/j.ynstr.2014.11.003  1
2015 O'Brien FE, Moloney GM, Scott KA, O'Connor RM, Clarke G, Dinan TG, Griffin BT, Cryan JF. Chronic P-glycoprotein inhibition increases the brain concentration of escitalopram: potential implications for treating depression. Pharmacology Research & Perspectives. 3: e00190. PMID 27022464 DOI: 10.1002/prp2.190  1
2015 Moloney RD, Golubeva AV, O'Connor RM, Kalinichev M, Dinan TG, Cryan JF. Negative allosteric modulation of the mGlu7 receptor reduces visceral hypersensitivity in a stress-sensitive rat strain. Neurobiology of Stress. 2: 28-33. PMID 26844237 DOI: 10.1016/j.ynstr.2015.04.001  1
2015 O' Mahony SM, Stilling RM, Dinan TG, Cryan JF. The microbiome and childhood diseases: Focus on brain-gut axis. Birth Defects Research. Part C, Embryo Today : Reviews. PMID 26706413 DOI: 10.1002/bdrc.21118  1
2015 Donovan MD, Schellekens H, Boylan GB, Cryan JF, Griffin BT. In vitro bidirectional permeability studies identify pharmacokinetic limitations of NKCC1 inhibitor bumetanide. European Journal of Pharmacology. PMID 26673740 DOI: 10.1016/j.ejphar.2015.12.001  1
2015 Moloney RD, Johnson AC, O'Mahony SM, Dinan TG, Greenwood-Van Meerveld B, Cryan JF. Stress and the Microbiota-Gut-Brain Axis in Visceral Pain: Relevance to Irritable Bowel Syndrome. Cns Neuroscience & Therapeutics. PMID 26662472 DOI: 10.1111/cns.12490  1
2015 Pusceddu MM, Nolan YM, Green HF, Robertson RC, Stanton C, Kelly P, Cryan JF, Dinan TG. The Omega-3 Polyunsaturated Fatty acid Docosahexaenoic acid (DHA) reverses Corticosterone-induced Changes in Cortical neurons. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). PMID 26657646 DOI: 10.1093/ijnp/pyv130  1
2015 McManus B, Korpela R, O'Connor P, Schellekens H, Cryan JF, Cotter PD, Nilaweera KN. Compared to casein, bovine lactoferrin reduces plasma leptin and corticosterone and affects hypothalamic gene expression without altering weight gain or fat mass in high fat diet fed C57/BL6J mice. Nutrition & Metabolism. 12: 53. PMID 26649066 DOI: 10.1186/s12986-015-0049-7  1
2015 O'Neill SM, Curran EA, Dalman C, Kenny LC, Kearney PM, Clarke G, Cryan JF, Dinan TG, Khashan AS. Birth by Caesarean Section and the Risk of Adult Psychosis: A Population-Based Cohort Study. Schizophrenia Bulletin. PMID 26615187 DOI: 10.1093/schbul/sbv152  1
2015 Kelly JR, Kennedy PJ, Cryan JF, Dinan TG, Clarke G, Hyland NP. Breaking down the barriers: the gut microbiome, intestinal permeability and stress-related psychiatric disorders. Frontiers in Cellular Neuroscience. 9: 392. PMID 26528128 DOI: 10.3389/fncel.2015.00392  1
2015 Jacobson LH, Sweeney FF, Kaupmann K, O'Leary OF, Gassmann M, Bettler B, Cryan JF. Differential Roles of GABAB1 Subunit Isoforms on Locomotor Responses to Acute and Repeated Administration of Cocaine. Behavioural Brain Research. PMID 26518330 DOI: 10.1016/j.bbr.2015.10.039  1
2015 Pusceddu MM, El Aidy S, Crispie F, O'Sullivan O, Cotter P, Stanton C, Kelly P, Cryan JF, Dinan TG. Correction: N-3 Polyunsaturated Fatty Acids (PUFAs) Reverse the Impact of Early-Life Stress on the Gut Microbiota. Plos One. 10: e0142228. PMID 26517367 DOI: 10.1371/journal.pone.0142228  1
2015 Foster JA, Lyte M, Meyer E, Cryan JF. Gut microbiota and brain function: An evolving field in neuroscience. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). PMID 26438800 DOI: 10.1093/ijnp/pyv114  1
2015 Felice VD, Moloney RD, Cryan JF, Dinan TG, O'Mahony SM. Visceral Pain and Psychiatric Disorders. Modern Trends in Pharmacopsychiatry. 30: 103-19. PMID 26436661 DOI: 10.1159/000435936  1
2015 O'Mahony SM, Clarke G, Dinan TG, Cryan JF. Early-life adversity and brain development: Is the microbiome a missing piece of the puzzle? Neuroscience. PMID 26432952 DOI: 10.1016/j.neuroscience.2015.09.068  1
2015 Pusceddu MM, El Aidy S, Crispie F, O'Sullivan O, Cotter P, Stanton C, Kelly P, Cryan JF, Dinan TG. N-3 Polyunsaturated Fatty Acids (PUFAs) Reverse the Impact of Early-Life Stress on the Gut Microbiota. Plos One. 10: e0139721. PMID 26426902 DOI: 10.1371/journal.pone.0139721  1
2015 Curran EA, Cryan JF, Kenny LC, Dinan TG, Kearney PM, Khashan AS. Obstetrical Mode of Delivery and Childhood Behavior and Psychological Development in a British Cohort. Journal of Autism and Developmental Disorders. PMID 26412364 DOI: 10.1007/s10803-015-2616-1  1
2015 Moloney RD, Stilling RM, Dinan TG, Cryan JF. Early-life stress-induced visceral hypersensitivity and anxiety behavior is reversed by histone deacetylase inhibition. Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society. PMID 26403543 DOI: 10.1111/nmo.12675  1
2015 Slattery DA, Uzunov DP, Cryan JF. 11-β hydroxysteroid type 1 knockout mice display an antidepressant-like phenotype in the forced swim test. Acta Neuropsychiatrica. 1-6. PMID 26400016 DOI: 10.1017/neu.2015.50  1
2015 Moloney RD, Dinan TG, Cryan JF. Stress & the microbiota-gut-brain axis in visceral pain. Psychoneuroendocrinology. 61: 8. PMID 26383295 DOI: 10.1016/j.psyneuen.2015.07.408  1
2015 Dinan TG, Cryan JF. The impact of gut microbiota on brain and behaviour: implications for psychiatry. Current Opinion in Clinical Nutrition and Metabolic Care. 18: 552-8. PMID 26372511 DOI: 10.1097/MCO.0000000000000221  1
2015 Donovan MD, Boylan GB, Murray DM, Cryan JF, Griffin BT. Treating disorders of the neonatal central nervous system: pharmacokinetic and pharmacodynamic considerations with a focus on antiepileptics. British Journal of Clinical Pharmacology. PMID 26302437 DOI: 10.1111/bcp.12753  1
2015 Crowley T, Fitzpatrick JM, Kuijper T, Cryan JF, O'Toole O, O'Leary OF, Downer EJ. Modulation of TLR3/TLR4 inflammatory signaling by the GABAB receptor agonist baclofen in glia and immune cells: relevance to therapeutic effects in multiple sclerosis. Frontiers in Cellular Neuroscience. 9: 284. PMID 26283920 DOI: 10.3389/fncel.2015.00284  1
2015 Allen AP, Naughton M, Dowling J, Walsh A, Ismail F, Shorten G, Scott L, McLoughlin DM, Cryan JF, Dinan TG, Clarke G. Serum BDNF as a peripheral biomarker of treatment-resistant depression and the rapid antidepressant response: A comparison of ketamine and ECT. Journal of Affective Disorders. 186: 306-311. PMID 26275358 DOI: 10.1016/j.jad.2015.06.033  1
2015 Desbonnet L, Clarke G, O'Sullivan O, Cotter PD, Dinan TG, Cryan JF. Re: Gut microbiota depletion from early adolescence in mice: Implications for brain and behaviour. Brain, Behavior, and Immunity. PMID 26271708 DOI: 10.1016/j.bbi.2015.07.011  1
2015 Zhdanov AV, Golubeva AV, Okkelman IA, Cryan JF, Papkovsky DB. Imaging of oxygen gradients in giant umbrella cells: an ex vivo PLIM study. American Journal of Physiology. Cell Physiology. 309: C501-9. PMID 26246428 DOI: 10.1152/ajpcell.00121.2015  1
2015 Cryan JF, Dinan TG. Gut microbiota: Microbiota and neuroimmune signalling-Metchnikoff to microglia. Nature Reviews. Gastroenterology & Hepatology. 12: 494-6. PMID 26215386 DOI: 10.1038/nrgastro.2015.127  1
2015 Sheikh AH, Barry DS, Gutierrez H, Cryan JF, O'Keeffe GW. Cadaveric anatomy in the future of medical education: What is the surgeons view? Anatomical Sciences Education. PMID 26213365 DOI: 10.1002/ase.1560  0.76
2015 McManus BL, Korpela R, Speakman JR, Cryan JF, Cotter PD, Nilaweera KN. Bovine serum albumin as the dominant form of dietary protein reduces subcutaneous fat mass, plasma leptin and plasma corticosterone in high fat-fed C57/BL6J mice. The British Journal of Nutrition. 114: 654-62. PMID 26189974 DOI: 10.1017/S0007114515002123  0.48
2015 O'Connor RM, Moloney RD, Glennon J, Vlachou S, Cryan JF. Enhancing glutamatergic transmission during adolescence reverses early-life stress-induced deficits in the rewarding effects of cocaine in rats. Neuropharmacology. 99: 168-176. PMID 26187394 DOI: 10.1016/j.neuropharm.2015.07.012  1
2015 Stilling RM, Ryan FJ, Hoban AE, Shanahan F, Clarke G, Claesson MJ, Dinan TG, Cryan JF. Microbes & neurodevelopment - Absence of microbiota during early life increases activity-related transcriptional pathways in the amygdala. Brain, Behavior, and Immunity. PMID 26184083 DOI: 10.1016/j.bbi.2015.07.009  1
2015 Malhotra M, Toulouse A, Godinho BM, Mc Carthy DJ, Cryan JF, O'Driscoll CM. RNAi therapeutics for brain cancer: current advancements in RNAi delivery strategies. Molecular Biosystems. PMID 26135606 DOI: 10.1039/c5mb00278h  1
2015 Golubeva AV, Crampton S, Desbonnet L, Edge D, O'Sullivan O, Lomasney KW, Zhdanov AV, Crispie F, Moloney RD, Borre YE, Cotter PD, Hyland NP, O'Halloran KD, Dinan TG, O'Keeffe GW, ... Cryan JF, et al. Prenatal stress-induced alterations in major physiological systems correlate with gut microbiota composition in adulthood. Psychoneuroendocrinology. 60: 58-74. PMID 26135201 DOI: 10.1016/j.psyneuen.2015.06.002  1
2015 Balta JY, Cronin M, Cryan JF, O'Mahony SM. Human preservation techniques in anatomy: A 21st century medical education perspective. Clinical Anatomy (New York, N.Y.). PMID 26118424 DOI: 10.1002/ca.22585  1
2015 Curran EA, Dalman C, Kearney PM, Kenny LC, Cryan JF, Dinan TG, Khashan AS. Association Between Obstetric Mode of Delivery and Autism Spectrum Disorder: A Population-Based Sibling Design Study. Jama Psychiatry. PMID 26107922 DOI: 10.1001/jamapsychiatry.2015.0846  1
2015 Felice D, O'Leary OF, Cryan JF, Dinan TG, Gardier AM, Sánchez C, David DJ. When ageing meets the blues: Are current antidepressants effective in depressed aged patients? Neuroscience and Biobehavioral Reviews. 55: 478-97. PMID 26054791 DOI: 10.1016/j.neubiorev.2015.06.005  1
2015 Stilling RM, Dinan TG, Cryan JF. The brain's Geppetto-microbes as puppeteers of neural function and behaviour? Journal of Neurovirology. PMID 26047662 DOI: 10.1007/s13365-015-0355-x  1
2015 Evans JC, McCarthy J, Torres-Fuentes C, Cryan JF, Ogier J, Darcy R, Watson RW, O'Driscoll CM. Cyclodextrin mediated delivery of NF-κB and SRF siRNA reduces the invasion potential of prostate cancer cells in vitro. Gene Therapy. PMID 26005860 DOI: 10.1038/gt.2015.50  0.52
2015 Looney AM, Walsh BH, Moloney G, Grenham S, Fagan A, O'Keeffe GW, Clarke G, Cryan JF, Dinan TG, Boylan GB, Murray DM. Downregulation of Umbilical Cord Blood Levels of miR-374a in Neonatal Hypoxic Ischemic Encephalopathy. The Journal of Pediatrics. PMID 26001314 DOI: 10.1016/j.jpeds.2015.04.060  1
2015 Pusceddu MM, Kelly P, Ariffin N, Cryan JF, Clarke G, Dinan TG. n-3 PUFAs have beneficial effects on anxiety and cognition in female rats: Effects of early life stress. Psychoneuroendocrinology. 58: 79-90. PMID 25965872 DOI: 10.1016/j.psyneuen.2015.04.015  1
2015 Burokas A, Moloney RD, Dinan TG, Cryan JF. Microbiota regulation of the Mammalian gut-brain axis. Advances in Applied Microbiology. 91: 1-62. PMID 25911232 DOI: 10.1016/bs.aambs.2015.02.001  1
2015 Khalaf SY, O'Neill SM, O'Keeffe LM, Henriksen TB, Kenny LC, Cryan JF, Khashan AS. The impact of obstetric mode of delivery on childhood behavior. Social Psychiatry and Psychiatric Epidemiology. PMID 25868660 DOI: 10.1007/s00127-015-1055-9  1
2015 Desbonnet L, Clarke G, Traplin A, O'Sullivan O, Crispie F, Moloney RD, Cotter PD, Dinan TG, Cryan JF. Gut microbiota depletion from early adolescence in mice: Implications for brain and behaviour. Brain, Behavior, and Immunity. 48: 165-173. PMID 25866195 DOI: 10.1016/j.bbi.2015.04.004  1
2015 Moloney RD, Dinan TG, Cryan JF. Strain-dependent variations in visceral sensitivity: relationship to stress, anxiety and spinal glutamate transporter expression. Genes, Brain, and Behavior. 14: 319-29. PMID 25851919 DOI: 10.1111/gbb.12216  1
2015 El Aidy S, Dinan TG, Cryan JF. Gut Microbiota: The Conductor in the Orchestra of Immune-Neuroendocrine Communication. Clinical Therapeutics. 37: 954-967. PMID 25846319 DOI: 10.1016/j.clinthera.2015.03.002  1
2015 Savignac HM, Tramullas M, Kiely B, Dinan TG, Cryan JF. Bifidobacteria modulate cognitive processes in an anxious mouse strain. Behavioural Brain Research. 287: 59-72. PMID 25794930 DOI: 10.1016/j.bbr.2015.02.044  1
2015 Golubeva AV, Moloney RD, O'Connor RM, Dinan TG, Cryan JF. Metabotropic Glutamate Receptors in Central Nervous System Diseases. Current Drug Targets. PMID 25777273  1
2015 Dinan TG, Stilling RM, Stanton C, Cryan JF. Collective unconscious: how gut microbes shape human behavior. Journal of Psychiatric Research. 63: 1-9. PMID 25772005 DOI: 10.1016/j.jpsychires.2015.02.021  1
2015 Moloney RD, O'Mahony SM, Dinan TG, Cryan JF. Stress-induced visceral pain: toward animal models of irritable-bowel syndrome and associated comorbidities. Frontiers in Psychiatry. 6: 15. PMID 25762939 DOI: 10.3389/fpsyt.2015.00015  1
2015 Schellekens H, De Francesco PN, Kandil D, Theeuwes WF, McCarthy T, van Oeffelen WE, Perelló M, Giblin L, Dinan TG, Cryan JF. Ghrelin's Orexigenic Effect Is Modulated via a Serotonin 2C Receptor Interaction. Acs Chemical Neuroscience. 6: 1186-97. PMID 25727097 DOI: 10.1021/cn500318q  1
2015 Prenderville JA, Kennedy PJ, Dinan TG, Cryan JF. Adding fuel to the fire: the impact of stress on the ageing brain. Trends in Neurosciences. 38: 13-25. PMID 25705750 DOI: 10.1016/j.tins.2014.11.001  1
2015 Gooding M, Malhotra M, McCarthy DJ, Godinho BM, Cryan JF, Darcy R, O'Driscoll CM. Synthesis and characterization of rabies virus glycoprotein-tagged amphiphilic cyclodextrins for siRNA delivery in human glioblastoma cells: in vitro analysis. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 71: 80-92. PMID 25703259 DOI: 10.1016/j.ejps.2015.02.007  1
2015 Ogbonnaya ES, Clarke G, Shanahan F, Dinan TG, Cryan JF, O'Leary OF. Adult Hippocampal Neurogenesis Is Regulated by the Microbiome. Biological Psychiatry. PMID 25700599 DOI: 10.1016/j.biopsych.2014.12.023  1
2015 Marques TM, Wall R, O'Sullivan O, Fitzgerald GF, Shanahan F, Quigley EM, Cotter PD, Cryan JF, Dinan TG, Ross RP, Stanton C. Dietary trans-10, cis-12-conjugated linoleic acid alters fatty acid metabolism and microbiota composition in mice. The British Journal of Nutrition. 113: 728-38. PMID 25697178 DOI: 10.1017/S0007114514004206  1
2015 McAllan L, Speakman JR, Cryan JF, Nilaweera KN. Whey protein isolate decreases murine stomach weight and intestinal length and alters the expression of Wnt signalling-associated genes. The British Journal of Nutrition. 1-8. PMID 25582423 DOI: 10.1017/S0007114514004024  1
2015 Scott KA, Hoban AE, Clarke G, Moloney GM, Dinan TG, Cryan JF. Thinking small: towards microRNA-based therapeutics for anxiety disorders. Expert Opinion On Investigational Drugs. 24: 529-42. PMID 25566796 DOI: 10.1517/13543784.2014.997873  1
2015 Donovan MD, O'Brien FE, Boylan GB, Cryan JF, Griffin BT. The effect of organic anion transporter 3 inhibitor probenecid on bumetanide levels in the brain: an integrated in vivo microdialysis study in the rat. The Journal of Pharmacy and Pharmacology. 67: 501-10. PMID 25490899 DOI: 10.1111/jphp.12341  1
2015 Cryan JF, Dinan TG. More than a gut feeling: the microbiota regulates neurodevelopment and behavior. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 40: 241-2. PMID 25482171 DOI: 10.1038/npp.2014.224  1
2015 Mc Carthy DJ, Malhotra M, O'Mahony AM, Cryan JF, O'Driscoll CM. Nanoparticles and the blood-brain barrier: advancing from in-vitro models towards therapeutic significance. Pharmaceutical Research. 32: 1161-85. PMID 25446769 DOI: 10.1007/s11095-014-1545-6  1
2015 Hyland NP, O'Mahony SM, O'Malley D, O'Mahony CM, Dinan TG, Cryan JF. Early-life stress selectively affects gastrointestinal but not behavioral responses in a genetic model of brain-gut axis dysfunction. Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society. 27: 105-13. PMID 25443141 DOI: 10.1111/nmo.12486  1
2015 Patterson E, Marques TM, O'Sullivan O, Fitzgerald P, Fitzgerald GF, Cotter PD, Dinan TG, Cryan JF, Stanton C, Ross RP. Streptozotocin-induced type-1-diabetes disease onset in Sprague-Dawley rats is associated with an altered intestinal microbiota composition and decreased diversity. Microbiology (Reading, England). 161: 182-93. PMID 25370749 DOI: 10.1099/mic.0.082610-0  1
2015 Curran EA, O'Neill SM, Cryan JF, Kenny LC, Dinan TG, Khashan AS, Kearney PM. Research review: Birth by caesarean section and development of autism spectrum disorder and attention-deficit/hyperactivity disorder: a systematic review and meta-analysis. Journal of Child Psychology and Psychiatry, and Allied Disciplines. 56: 500-8. PMID 25348074 DOI: 10.1111/jcpp.12351  1
2015 Kennedy PJ, Allen AP, O'Neill A, Quigley EM, Cryan JF, Dinan TG, Clarke G. Acute tryptophan depletion reduces kynurenine levels: implications for treatment of impaired visuospatial memory performance in irritable bowel syndrome. Psychopharmacology. 232: 1357-71. PMID 25338777 DOI: 10.1007/s00213-014-3767-z  1
2015 Godinho BM, Malhotra M, O'Driscoll CM, Cryan JF. Delivering a disease-modifying treatment for Huntington's disease. Drug Discovery Today. 20: 50-64. PMID 25256777 DOI: 10.1016/j.drudis.2014.09.011  1
2015 O'Malley D, Buckley MM, McKernan DP, Quigley EM, Cryan JF, Dinan TG. Soluble mediators in plasma from irritable bowel syndrome patients excite rat submucosal neurons. Brain, Behavior, and Immunity. 44: 57-67. PMID 25150006 DOI: 10.1016/j.bbi.2014.08.005  1
2015 O'Leary OF, Dinan TG, Cryan JF. Faster, better, stronger: towards new antidepressant therapeutic strategies. European Journal of Pharmacology. 753: 32-50. PMID 25092200 DOI: 10.1016/j.ejphar.2014.07.046  1
2015 O'Mahony SM, Clarke G, Borre YE, Dinan TG, Cryan JF. Serotonin, tryptophan metabolism and the brain-gut-microbiome axis. Behavioural Brain Research. 277: 32-48. PMID 25078296 DOI: 10.1016/j.bbr.2014.07.027  1
2015 Dollard J, Kearney P, Clarke G, Moloney G, Cryan JF, Dinan TG. A prospective study of C-reactive protein as a state marker in Cardiac Syndrome X. Brain, Behavior, and Immunity. 43: 27-32. PMID 25064176 DOI: 10.1016/j.bbi.2014.07.011  1
2015 Filip M, Frankowska M, Sadakierska-Chudy A, Suder A, Szumiec L, Mierzejewski P, Bienkowski P, Przegali?ski E, Cryan JF. GABAB receptors as a therapeutic strategy in substance use disorders: focus on positive allosteric modulators. Neuropharmacology. 88: 36-47. PMID 24971600 DOI: 10.1016/j.neuropharm.2014.06.016  1
2015 Torres-Fuentes C, Schellekens H, Dinan TG, Cryan JF. A natural solution for obesity: bioactives for the prevention and treatment of weight gain. A review. Nutritional Neuroscience. 18: 49-65. PMID 24621068 DOI: 10.1179/1476830513Y.0000000099  1
2015 Crowley T, Fitzpatrick JM, Kuijper T, Cryan JF, O’Toole O, O’Leary OF, Downer EJ. Modulation of TLR3/TLR4 inflammatory signaling by the GABAB receptor agonist baclofen in glia and immune cells: Relevance to therapeutic effects in multiple sclerosis Frontiers in Cellular Neuroscience. 9. DOI: 10.3389/fncel.2015.00284  1
2015 Cryan JF, Dinan TG. Gut microbiota: Microbiota and neuroimmune signalling - Metchnikoff to microglia Nature Reviews Gastroenterology and Hepatology. 12: 494-496. DOI: 10.1038/nrgastro.2015.127  1
2015 McManus BL, Korpela R, Speakman JR, Cryan JF, Cotter PD, Nilaweera KN. Bovine serum albumin as the dominant form of dietary protein reduces subcutaneous fat mass, plasma leptin and plasma corticosterone in high fat-fed C57/BL6J mice British Journal of Nutrition. DOI: 10.1017/S0007114515002123  1
2015 Rea K, Dinan TG, Cryan JF. The microbiome: A key regulator of stress and neuroinflammation Neurobiology of Stress. DOI: 10.1016/j.ynstr.2016.03.001  1
2015 Moloney RD, Golubeva AV, O'Connor RM, Kalinichev M, Dinan TG, Cryan JF. Negative allosteric modulation of the mGlu7 receptor reduces visceral hypersensitivity in a stress-sensitive rat strain Neurobiology of Stress. 2: 28-33. DOI: 10.1016/j.ynstr.2015.04.001  1
2015 Levone BR, Cryan JF, O'Leary OF. Role of adult hippocampal neurogenesis in stress resilience Neurobiology of Stress. 1: 147-155. DOI: 10.1016/j.ynstr.2014.11.003  1
2015 O'Connor RM, Moloney RD, Glennon J, Vlachou S, Cryan JF. Enhancing glutamatergic transmission during adolescence reverses early-life stress-induced deficits in the rewarding effects of cocaine in rats Neuropharmacology. 99: 168-176. DOI: 10.1016/j.neuropharm.2015.07.012  1
2015 Hurley AM, Kennedy PJ, O’Connor L, Dinan TG, Cryan JF, Boylan G, O’Reilly BA. SOS save our surgeons: Stress levels reduced by robotic surgery Gynecological Surgery. 12: 197-206. DOI: 10.1007/s10397-015-0891-7  1
2015 Mc Carthy T, Green BD, Calderwood D, Gillespie A, Cryan JF, Giblin L. STC-1 cells The Impact of Food Bioactives On Health: in Vitro and Ex Vivo Models. 211-220. DOI: 10.1007/978-3-319-16104-4_19  0.48
2015 Sheikh AH, Barry DS, Gutierrez H, Cryan JF, O'Keeffe GW. Cadaveric anatomy in the future of medical education: What is the surgeons view? Anatomical Sciences Education. DOI: 10.1002/ase.1560  0.76
2015 Stilling RM, Dinan TG, Cryan JF. The Master Puppeteer?: The impact of microbes on brain and behaviour Microbiology Today. 42: 26-29.  1
2014 O'Leary OF, Cryan JF. A ventral view on antidepressant action: roles for adult hippocampal neurogenesis along the dorsoventral axis. Trends in Pharmacological Sciences. 35: 675-87. PMID 25455365 DOI: 10.1016/j.tips.2014.09.011  1
2014 Stilling RM, Bordenstein SR, Dinan TG, Cryan JF. Friends with social benefits: host-microbe interactions as a driver of brain evolution and development? Frontiers in Cellular and Infection Microbiology. 4: 147. PMID 25401092 DOI: 10.3389/fcimb.2014.00147  1
2014 Mayer EA, Knight R, Mazmanian SK, Cryan JF, Tillisch K. Gut microbes and the brain: paradigm shift in neuroscience. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 15490-6. PMID 25392516 DOI: 10.1523/JNEUROSCI.3299-14.2014  1
2014 Kennedy PJ, Cryan JF, Dinan TG, Clarke G. Irritable bowel syndrome: a microbiome-gut-brain axis disorder? World Journal of Gastroenterology : Wjg. 20: 14105-25. PMID 25339800 DOI: 10.3748/wjg.v20.i39.14105  1
2014 O'Leary OF, Felice D, Galimberti S, Savignac HM, Bravo JA, Crowley T, El Yacoubi M, Vaugeois JM, Gassmann M, Bettler B, Dinan TG, Cryan JF. GABAB(1) receptor subunit isoforms differentially regulate stress resilience. Proceedings of the National Academy of Sciences of the United States of America. 111: 15232-7. PMID 25288769 DOI: 10.1073/pnas.1404090111  1
2014 Dinan TG, Borre YE, Cryan JF. Genomics of schizophrenia: time to consider the gut microbiome? Molecular Psychiatry. 19: 1252-7. PMID 25288135 DOI: 10.1038/mp.2014.93  1
2014 Lawrence AJ, Cryan JF. Found in translation? Commentary on a BJP themed issue about animal models in neuropsychiatry research. British Journal of Pharmacology. 171: 4521-3. PMID 25257223 DOI: 10.1111/bph.12887  1
2014 Savignac HM, Kiely B, Dinan TG, Cryan JF. Bifidobacteria exert strain-specific effects on stress-related behavior and physiology in BALB/c mice. Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society. 26: 1615-27. PMID 25251188 DOI: 10.1111/nmo.12427  1
2014 Slattery DA, Cryan JF. The ups and downs of modelling mood disorders in rodents. Ilar Journal / National Research Council, Institute of Laboratory Animal Resources. 55: 297-309. PMID 25225308 DOI: 10.1093/ilar/ilu026  1
2014 Patterson E, Cryan JF, Fitzgerald GF, Ross RP, Dinan TG, Stanton C. Gut microbiota, the pharmabiotics they produce and host health. The Proceedings of the Nutrition Society. 73: 477-89. PMID 25196939 DOI: 10.1017/S0029665114001426  1
2014 Browne CA, Hanke J, Rose C, Walsh I, Foley T, Clarke G, Schwegler H, Cryan JF, Yilmazer-Hanke D. Effect of acute swim stress on plasma corticosterone and brain monoamine levels in bidirectionally selected DxH recombinant inbred mouse strains differing in fear recall and extinction. Stress (Amsterdam, Netherlands). 17: 471-83. PMID 25117886 DOI: 10.3109/10253890.2014.954104  1
2014 Murphy KP, Crush L, O'Malley E, Daly FE, O'Tuathaigh CM, O'Connor OJ, Cryan JF, Maher MM. Medical student knowledge regarding radiology before and after a radiological anatomy module: implications for vertical integration and self-directed learning. Insights Into Imaging. 5: 629-34. PMID 25107581 DOI: 10.1007/s13244-014-0346-0  1
2014 O'Mahony SM, Felice VD, Nally K, Savignac HM, Claesson MJ, Scully P, Woznicki J, Hyland NP, Shanahan F, Quigley EM, Marchesi JR, O'Toole PW, Dinan TG, Cryan JF. Disturbance of the gut microbiota in early-life selectively affects visceral pain in adulthood without impacting cognitive or anxiety-related behaviors in male rats. Neuroscience. 277: 885-901. PMID 25088912 DOI: 10.1016/j.neuroscience.2014.07.054  1
2014 Torres-Fuentes C, Theeuwes WF, McMullen MK, McMullen AK, Dinan TG, Cryan JF, Schellekens H. Devil's Claw to suppress appetite--ghrelin receptor modulation potential of a Harpagophytum procumbens root extract. Plos One. 9: e103118. PMID 25068823 DOI: 10.1371/journal.pone.0103118  1
2014 Kennedy PJ, Cryan JF, Quigley EM, Dinan TG, Clarke G. A sustained hypothalamic-pituitary-adrenal axis response to acute psychosocial stress in irritable bowel syndrome. Psychological Medicine. 44: 3123-34. PMID 25065954 DOI: 10.1017/S003329171400052X  1
2014 Borre YE, Moloney RD, Clarke G, Dinan TG, Cryan JF. The impact of microbiota on brain and behavior: mechanisms & therapeutic potential. Advances in Experimental Medicine and Biology. 817: 373-403. PMID 24997043 DOI: 10.1007/978-1-4939-0897-4_17  1
2014 Wall R, Cryan JF, Ross RP, Fitzgerald GF, Dinan TG, Stanton C. Bacterial neuroactive compounds produced by psychobiotics. Advances in Experimental Medicine and Biology. 817: 221-39. PMID 24997036 DOI: 10.1007/978-1-4939-0897-4_10  1
2014 Godinho BM, Ogier JR, Quinlan A, Darcy R, Griffin BT, Cryan JF, O'Driscoll CM. PEGylated cyclodextrins as novel siRNA nanosystems: correlations between polyethylene glycol length and nanoparticle stability. International Journal of Pharmaceutics. 473: 105-12. PMID 24992319 DOI: 10.1016/j.ijpharm.2014.06.054  1
2014 Borre YE, O'Keeffe GW, Clarke G, Stanton C, Dinan TG, Cryan JF. Microbiota and neurodevelopmental windows: implications for brain disorders. Trends in Molecular Medicine. 20: 509-18. PMID 24956966 DOI: 10.1016/j.molmed.2014.05.002  1
2014 Clarke G, Stilling RM, Kennedy PJ, Stanton C, Cryan JF, Dinan TG. Minireview: Gut microbiota: the neglected endocrine organ. Molecular Endocrinology (Baltimore, Md.). 28: 1221-38. PMID 24892638 DOI: 10.1210/me.2014-1108  1
2014 Lomasney KW, Cryan JF, Hyland NP. Converging effects of a Bifidobacterium and Lactobacillus probiotic strain on mouse intestinal physiology. American Journal of Physiology. Gastrointestinal and Liver Physiology. 307: G241-7. PMID 24852567 DOI: 10.1152/ajpgi.00401.2013  1
2014 Clarke G, O'Mahony SM, Dinan TG, Cryan JF. Priming for health: gut microbiota acquired in early life regulates physiology, brain and behaviour. Acta Paediatrica (Oslo, Norway : 1992). 103: 812-9. PMID 24798884 DOI: 10.1111/apa.12674  1
2014 Bravo JA, Dinan TG, Cryan JF. Early-life stress induces persistent alterations in 5-HT1A receptor and serotonin transporter mRNA expression in the adult rat brain. Frontiers in Molecular Neuroscience. 7: 24. PMID 24782706 DOI: 10.3389/fnmol.2014.00024  1
2014 El Aidy S, Dinan TG, Cryan JF. Immune modulation of the brain-gut-microbe axis. Frontiers in Microbiology. 5: 146. PMID 24778631 DOI: 10.3389/fmicb.2014.00146  1
2014 Golubeva AV, Zhdanov AV, Mallel G, Dinan TG, Cryan JF. The mouse cyclophosphamide model of bladder pain syndrome: tissue characterization, immune profiling, and relationship to metabotropic glutamate receptors. Physiological Reports. 2: e00260. PMID 24760514 DOI: 10.1002/phy2.260  1
2014 Lomasney KW, Houston A, Shanahan F, Dinan TG, Cryan JF, Hyland NP. Selective influence of host microbiota on cAMP-mediated ion transport in mouse colon. Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society. 26: 887-90. PMID 24612168 DOI: 10.1111/nmo.12328  1
2014 Gee CE, Peterlik D, Neuhäuser C, Bouhelal R, Kaupmann K, Laue G, Uschold-Schmidt N, Feuerbach D, Zimmermann K, Ofner S, Cryan JF, van der Putten H, Fendt M, Vranesic I, Glatthar R, et al. Blocking metabotropic glutamate receptor subtype 7 (mGlu7) via the Venus flytrap domain (VFTD) inhibits amygdala plasticity, stress, and anxiety-related behavior. The Journal of Biological Chemistry. 289: 10975-87. PMID 24596089 DOI: 10.1074/jbc.M113.542654  1
2014 McAllan L, Skuse P, Cotter PD, O'Connor P, Cryan JF, Ross RP, Fitzgerald G, Roche HM, Nilaweera KN. Protein quality and the protein to carbohydrate ratio within a high fat diet influences energy balance and the gut microbiota in C57BL/6J mice. Plos One. 9: e88904. PMID 24520424 DOI: 10.1371/journal.pone.0088904  1
2014 Felice VD, Gibney SM, Gosselin RD, Dinan TG, O'Mahony SM, Cryan JF. Differential activation of the prefrontal cortex and amygdala following psychological stress and colorectal distension in the maternally separated rat. Neuroscience. 267: 252-62. PMID 24513388 DOI: 10.1016/j.neuroscience.2014.01.064  1
2014 Melamed O, Levav-Rabkin T, Zukerman C, Clarke G, Cryan JF, Dinan TG, Grossman Y, Golan HM. Long-lasting glutamatergic modulation induced by neonatal GABA enhancement in mice. Neuropharmacology. 79: 616-25. PMID 24462620 DOI: 10.1016/j.neuropharm.2013.12.015  1
2014 O'Malley D, Julio-Piepera M, Dinan TG, Cryan JF. Strain differences in stress-induced changes in central CRF1 receptor expression. Neuroscience Letters. 561: 192-7. PMID 24406148 DOI: 10.1016/j.neulet.2013.12.065  1
2014 Naughton M, Clarke G, O'Leary OF, Cryan JF, Dinan TG. A review of ketamine in affective disorders: current evidence of clinical efficacy, limitations of use and pre-clinical evidence on proposed mechanisms of action. Journal of Affective Disorders. 156: 24-35. PMID 24388038 DOI: 10.1016/j.jad.2013.11.014  1
2014 Tramullas M, Finger BC, Moloney RD, Golubeva AV, Moloney G, Dinan TG, Cryan JF. Toll-like receptor 4 regulates chronic stress-induced visceral pain in mice. Biological Psychiatry. 76: 340-8. PMID 24331544 DOI: 10.1016/j.biopsych.2013.11.004  1
2014 O'Connor RM, Cryan JF. Adolescent brain vulnerability and psychopathology through the generations: role of diet and dopamine. Biological Psychiatry. 75: 4-6. PMID 24314061 DOI: 10.1016/j.biopsych.2013.10.022  1
2014 Stilling RM, Dinan TG, Cryan JF. Microbial genes, brain & behaviour - epigenetic regulation of the gut-brain axis. Genes, Brain, and Behavior. 13: 69-86. PMID 24286462 DOI: 10.1111/gbb.12109  1
2014 Moloney RD, Desbonnet L, Clarke G, Dinan TG, Cryan JF. The microbiome: stress, health and disease. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 25: 49-74. PMID 24281320 DOI: 10.1007/s00335-013-9488-5  1
2014 O'Brien FE, O'Connor RM, Clarke G, Donovan MD, Dinan TG, Griffin BT, Cryan JF. The P-glycoprotein inhibitor cyclosporin A differentially influences behavioural and neurochemical responses to the antidepressant escitalopram. Behavioural Brain Research. 261: 17-25. PMID 24280122 DOI: 10.1016/j.bbr.2013.11.027  1
2014 O'Malley D, Julio-Pieper M, O'Mahony SM, Dinan TG, Cryan JF. Differential visceral pain sensitivity and colonic morphology in four common laboratory rat strains. Experimental Physiology. 99: 359-67. PMID 24243837 DOI: 10.1113/expphysiol.2013.076109  1
2014 Allen AP, Kennedy PJ, Cryan JF, Dinan TG, Clarke G. Biological and psychological markers of stress in humans: focus on the Trier Social Stress Test. Neuroscience and Biobehavioral Reviews. 38: 94-124. PMID 24239854 DOI: 10.1016/j.neubiorev.2013.11.005  1
2014 O'Leary OF, O'Brien FE, O'Connor RM, Cryan JF. Drugs, genes and the blues: pharmacogenetics of the antidepressant response from mouse to man. Pharmacology, Biochemistry, and Behavior. 123: 55-76. PMID 24161683 DOI: 10.1016/j.pbb.2013.10.015  1
2014 Godinho BM, McCarthy DJ, Torres-Fuentes C, Beltrán CJ, McCarthy J, Quinlan A, Ogier JR, Darcy R, O'Driscoll CM, Cryan JF. Differential nanotoxicological and neuroinflammatory liabilities of non-viral vectors for RNA interference in the central nervous system. Biomaterials. 35: 489-99. PMID 24138827 DOI: 10.1016/j.biomaterials.2013.09.068  1
2014 Sweeney FF, O'Leary OF, Cryan JF. Activation but not blockade of GABAB receptors during early-life alters anxiety in adulthood in BALB/c mice. Neuropharmacology. 81: 303-10. PMID 24050962 DOI: 10.1016/j.neuropharm.2013.08.039  1
2014 Kennedy PJ, Clarke G, O'Neill A, Groeger JA, Quigley EM, Shanahan F, Cryan JF, Dinan TG. Cognitive performance in irritable bowel syndrome: evidence of a stress-related impairment in visuospatial memory. Psychological Medicine. 44: 1553-66. PMID 23985155 DOI: 10.1017/S0033291713002171  1
2014 Desbonnet L, Clarke G, Shanahan F, Dinan TG, Cryan JF. Microbiota is essential for social development in the mouse. Molecular Psychiatry. 19: 146-8. PMID 23689536 DOI: 10.1038/mp.2013.65  1
2014 Marques TM, Cryan JF, Shanahan F, Fitzgerald GF, Ross RP, Dinan TG, Stanton C. Gut microbiota modulation and implications for host health: Dietary strategies to influence the gut-brain axis Innovative Food Science and Emerging Technologies. 22: 239-247. DOI: 10.1016/j.ifset.2013.10.016  1
2014 Schellekens H, Nongonierma AB, Clarke G, van Oeffelen WEPA, FitzGerald RJ, Dinan TG, Cryan JF. Milk protein-derived peptides induce 5-HT2C-mediated satiety invivo International Dairy Journal. 38: 55-64. DOI: 10.1016/j.idairyj.2014.04.004  1
2013 Halaris A, Leonard BE. Preface. Modern Trends in Pharmacopsychiatry. 28: VII - VIII. PMID 25286461 DOI: 10.1159/000346450  0.48
2013 Carroll SY, O'Mahony SM, Grenham S, Cryan JF, Hyland NP. Disodium cromoglycate reverses colonic visceral hypersensitivity and influences colonic ion transport in a stress-sensitive rat strain. Plos One. 8: e84718. PMID 24367692 DOI: 10.1371/journal.pone.0084718  1
2013 Cryan JF, Dinan TG. Unraveling the longstanding scars of early neurodevelopmental stress. Biological Psychiatry. 74: 788-9. PMID 24188696 DOI: 10.1016/j.biopsych.2013.10.004  1
2013 Davey KJ, Cotter PD, O'Sullivan O, Crispie F, Dinan TG, Cryan JF, O'Mahony SM. Antipsychotics and the gut microbiome: olanzapine-induced metabolic dysfunction is attenuated by antibiotic administration in the rat. Translational Psychiatry. 3: e309. PMID 24084940 DOI: 10.1038/tp.2013.83  1
2013 Schellekens H, Dinan TG, Cryan JF. Taking two to tango: a role for ghrelin receptor heterodimerization in stress and reward. Frontiers in Neuroscience. 7: 148. PMID 24009547 DOI: 10.3389/fnins.2013.00148  1
2013 Hoestgaard-Jensen K, O'Connor RM, Dalby NO, Simonsen C, Finger BC, Golubeva A, Hammer H, Bergmann ML, Kristiansen U, Krogsgaard-Larsen P, Bräuner-Osborne H, Ebert B, Frølund B, Cryan JF, Jensen AA. The orthosteric GABAA receptor ligand Thio-4-PIOL displays distinctly different functional properties at synaptic and extrasynaptic receptors. British Journal of Pharmacology. 170: 919-32. PMID 23957253 DOI: 10.1111/bph.12340  1
2013 Sweeney FF, O'Leary OF, Cryan JF. GABAB receptor ligands do not modify conditioned fear responses in BALB/c mice. Behavioural Brain Research. 256: 151-6. PMID 23933467 DOI: 10.1016/j.bbr.2013.07.035  1
2013 O'Brien FE, Clarke G, Dinan TG, Cryan JF, Griffin BT. Human P-glycoprotein differentially affects antidepressant drug transport: relevance to blood-brain barrier permeability. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 16: 2259-72. PMID 23931269 DOI: 10.1017/S1461145713000692  1
2013 Dinan TG, Cryan JF. Melancholic microbes: a link between gut microbiota and depression? Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society. 25: 713-9. PMID 23910373 DOI: 10.1111/nmo.12198  1
2013 O'Mahony AM, Godinho BM, Cryan JF, O'Driscoll CM. Non-viral nanosystems for gene and small interfering RNA delivery to the central nervous system: formulating the solution. Journal of Pharmaceutical Sciences. 102: 3469-84. PMID 23893329 DOI: 10.1002/jps.23672  1
2013 O' Mahony SM, Clarke G, McKernan DP, Bravo JA, Dinan TG, Cryan JF. Differential visceral nociceptive, behavioural and neurochemical responses to an immune challenge in the stress-sensitive Wistar Kyoto rat strain. Behavioural Brain Research. 253: 310-7. PMID 23872358 DOI: 10.1016/j.bbr.2013.07.023  1
2013 O'Mahony AM, Ogier J, Darcy R, Cryan JF, O'Driscoll CM. Cationic and PEGylated Amphiphilic Cyclodextrins: Co-Formulation Opportunities for Neuronal Sirna Delivery. Plos One. 8: e66413. PMID 23805220 DOI: 10.1371/journal.pone.0066413  1
2013 Dinan TG, Stanton C, Cryan JF. Psychobiotics: a novel class of psychotropic. Biological Psychiatry. 74: 720-6. PMID 23759244 DOI: 10.1016/j.biopsych.2013.05.001  1
2013 McAllan L, Keane D, Schellekens H, Roche HM, Korpela R, Cryan JF, Nilaweera KN. Whey protein isolate counteracts the effects of a high-fat diet on energy intake and hypothalamic and adipose tissue expression of energy balance-related genes. The British Journal of Nutrition. 110: 2114-26. PMID 23731955 DOI: 10.1017/S0007114513001396  1
2013 O'Connor RM, Grenham S, Dinan TG, Cryan JF. microRNAs as novel antidepressant targets: converging effects of ketamine and electroconvulsive shock therapy in the rat hippocampus. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 16: 1885-92. PMID 23684180 DOI: 10.1017/S1461145713000448  1
2013 O'Brien FE, O'Connor RM, Clarke G, Dinan TG, Griffin BT, Cryan JF. P-glycoprotein inhibition increases the brain distribution and antidepressant-like activity of escitalopram in rodents. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 2209-19. PMID 23670590 DOI: 10.1038/npp.2013.120  1
2013 O'Connor RM, Thakker DR, Schmutz M, van der Putten H, Hoyer D, Flor PJ, Cryan JF. Adult siRNA-induced knockdown of mGlu7 receptors reduces anxiety in the mouse. Neuropharmacology. 72: 66-73. PMID 23603202 DOI: 10.1016/j.neuropharm.2013.03.028  1
2013 O'Leary OF, Cryan JF. Towards translational rodent models of depression. Cell and Tissue Research. 354: 141-53. PMID 23525777 DOI: 10.1007/s00441-013-1587-9  1
2013 Schellekens H, McNamara O, Dinan TG, McCarthy JV, McGlacken GP, Cryan JF. Semagacestat, a γ-secretase inhibitor, activates the growth hormone secretagogue (GHS-R1a) receptor. The Journal of Pharmacy and Pharmacology. 65: 528-38. PMID 23488781 DOI: 10.1111/jphp.12010  1
2013 O'Connor RM, Cryan JF. The effects of mGlu₇ receptor modulation in behavioural models sensitive to antidepressant action in two mouse strains. Behavioural Pharmacology. 24: 105-13. PMID 23455446 DOI: 10.1097/FBP.0b013e32835efc78  1
2013 Nongonierma AB, Schellekens H, Dinan TG, Cryan JF, FitzGerald RJ. Milk protein hydrolysates activate 5-HT(2C) serotonin receptors: influence of the starting substrate and isolation of bioactive fractions. Food & Function. 4: 728-37. PMID 23435627 DOI: 10.1039/c3fo30309h  1
2013 Schellekens H, Dinan TG, Cryan JF. Ghrelin at the interface of obesity and reward. Vitamins and Hormones. 91: 285-323. PMID 23374722 DOI: 10.1016/B978-0-12-407766-9.00013-4  1
2013 O'Malley D, Cryan JF, Dinan TG. Crosstalk between interleukin-6 and corticotropin-releasing factor modulate submucosal plexus activity and colonic secretion. Brain, Behavior, and Immunity. 30: 115-24. PMID 23369733 DOI: 10.1016/j.bbi.2013.01.078  1
2013 O'Mahony AM, Desgranges S, Ogier J, Quinlan A, Devocelle M, Darcy R, Cryan JF, O'Driscoll CM. In vitro investigations of the efficacy of cyclodextrin-siRNA complexes modified with lipid-PEG-Octaarginine: towards a formulation strategy for non-viral neuronal siRNA delivery. Pharmaceutical Research. 30: 1086-98. PMID 23192687 DOI: 10.1007/s11095-012-0945-8  1
2013 Schellekens H, van Oeffelen WE, Dinan TG, Cryan JF. Promiscuous dimerization of the growth hormone secretagogue receptor (GHS-R1a) attenuates ghrelin-mediated signaling. The Journal of Biological Chemistry. 288: 181-91. PMID 23161547 DOI: 10.1074/jbc.M112.382473  1
2013 Julio-Pieper M, O'Connor RM, Dinan TG, Cryan JF. Regulation of the brain-gut axis by group III metabotropic glutamate receptors. European Journal of Pharmacology. 698: 19-30. PMID 23123053 DOI: 10.1016/j.ejphar.2012.10.027  1
2013 Godinho BM, Ogier JR, Darcy R, O'Driscoll CM, Cryan JF. Self-assembling modified β-cyclodextrin nanoparticles as neuronal siRNA delivery vectors: focus on Huntington's disease. Molecular Pharmaceutics. 10: 640-9. PMID 23116281 DOI: 10.1021/mp3003946  1
2013 O'Leary OF, Zandy S, Dinan TG, Cryan JF. Lithium augmentation of the effects of desipramine in a mouse model of treatment-resistant depression: a role for hippocampal cell proliferation. Neuroscience. 228: 36-46. PMID 23069753 DOI: 10.1016/j.neuroscience.2012.09.072  1
2013 O'Connor RM, Pusceddu MM, O'Leary OF, Savignac HM, Bravo JA, El Yacoubi M, Vaugeois JM, Dinan TG, Cryan JF. Hippocampal group III mGlu receptor mRNA levels are not altered in specific mouse models of stress, depression and antidepressant action. Pharmacology, Biochemistry, and Behavior. 103: 561-7. PMID 23059104 DOI: 10.1016/j.pbb.2012.09.017  1
2013 Browne CA, Clarke G, Hanke J, Dinan TG, Schwegler H, Yilmazer-Hanke DM, Cryan JF. Alterations in prefrontal cortical serotonin and antidepressant-like behavior in a novel C3H/HeJxDBA/2J recombinant inbred mouse strain. Behavioural Brain Research. 236: 283-8. PMID 22960457 DOI: 10.1016/j.bbr.2012.08.012  1
2013 Clarke G, Grenham S, Scully P, Fitzgerald P, Moloney RD, Shanahan F, Dinan TG, Cryan JF. The microbiome-gut-brain axis during early life regulates the hippocampal serotonergic system in a sex-dependent manner. Molecular Psychiatry. 18: 666-73. PMID 22688187 DOI: 10.1038/mp.2012.77  1
2013 O' Connor RM, Pusceddu MM, Dinan TG, Cryan JF. Impact of early-life stress, on group III mGlu receptor levels in the rat hippocampus: effects of ketamine, electroconvulsive shock therapy and fluoxetine treatment. Neuropharmacology. 66: 236-41. PMID 22609536 DOI: 10.1016/j.neuropharm.2012.05.006  1
2013 Barrett E, Dinan TG, Cryan JF, Quigley EMM, Shanahan F, O'Toole PW, Fitzgerald GF, Stanton C, Ross RP. Effects of the intestinal microbiota on behavior and brain biochemistry World Review of Nutrition and Dietetics. 107: 56-63. DOI: 10.1159/000345749  1
2012 Barrett E, Fitzgerald P, Dinan TG, Cryan JF, Ross RP, Quigley EM, Shanahan F, Kiely B, Fitzgerald GF, O'Toole PW, Stanton C. Bifidobacterium breve with α-linolenic acid and linoleic acid alters fatty acid metabolism in the maternal separation model of irritable bowel syndrome. Plos One. 7: e48159. PMID 23185248 DOI: 10.1371/journal.pone.0048159  1
2012 O'Malley D, Dinan TG, Cryan JF. Interleukin-6 modulates colonic transepithelial ion transport in the stress-sensitive wistar kyoto rat. Frontiers in Pharmacology. 3: 190. PMID 23162465 DOI: 10.3389/fphar.2012.00190  1
2012 O'Mahony SM, Tramullas M, Fitzgerald P, Cryan JF. Rodent models of colorectal distension. Current Protocols in Neuroscience / Editorial Board, Jacqueline N. Crawley ... [Et Al.]. Unit 9.40. PMID 23093353 DOI: 10.1002/0471142301.ns0940s61  1
2012 O'Mahony AM, Godinho BM, Ogier J, Devocelle M, Darcy R, Cryan JF, O'Driscoll CM. Click-modified cyclodextrins as nonviral vectors for neuronal siRNA delivery. Acs Chemical Neuroscience. 3: 744-52. PMID 23077718 DOI: 10.1021/cn3000372  1
2012 Bravo JA, Julio-Pieper M, Forsythe P, Kunze W, Dinan TG, Bienenstock J, Cryan JF. Communication between gastrointestinal bacteria and the nervous system. Current Opinion in Pharmacology. 12: 667-72. PMID 23041079 DOI: 10.1016/j.coph.2012.09.010  1
2012 O'Mahony AM, Doyle D, Darcy R, Cryan JF, O'Driscoll CM. Characterisation of cationic amphiphilic cyclodextrins for neuronal delivery of siRNA: effect of reversing primary and secondary face modifications. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 47: 896-903. PMID 23022516 DOI: 10.1016/j.ejps.2012.08.020  1
2012 Cryan JF, Dinan TG. Mind-altering microorganisms: the impact of the gut microbiota on brain and behaviour. Nature Reviews. Neuroscience. 13: 701-12. PMID 22968153 DOI: 10.1038/nrn3346  1
2012 Browne CA, O'Brien FE, Connor TJ, Dinan TG, Cryan JF. Differential lipopolysaccharide-induced immune alterations in the hippocampus of two mouse strains: effects of stress. Neuroscience. 225: 237-48. PMID 22917616 DOI: 10.1016/j.neuroscience.2012.08.031  1
2012 Felice D, O'Leary OF, Pizzo RC, Cryan JF. Blockade of the GABA(B) receptor increases neurogenesis in the ventral but not dorsal adult hippocampus: relevance to antidepressant action. Neuropharmacology. 63: 1380-8. PMID 22884610 DOI: 10.1016/j.neuropharm.2012.06.066  1
2012 Schellekens H, Finger BC, Dinan TG, Cryan JF. Ghrelin signalling and obesity: at the interface of stress, mood and food reward. Pharmacology & Therapeutics. 135: 316-26. PMID 22749794 DOI: 10.1016/j.pharmthera.2012.06.004  1
2012 Clarke G, McKernan DP, Gaszner G, Quigley EM, Cryan JF, Dinan TG. A Distinct Profile of Tryptophan Metabolism along the Kynurenine Pathway Downstream of Toll-Like Receptor Activation in Irritable Bowel Syndrome. Frontiers in Pharmacology. 3: 90. PMID 22661947 DOI: 10.3389/fphar.2012.00090  1
2012 O'Mahony AM, Ogier J, Desgranges S, Cryan JF, Darcy R, O'Driscoll CM. A click chemistry route to 2-functionalised PEGylated and cationic β-cyclodextrins: co-formulation opportunities for siRNA delivery. Organic & Biomolecular Chemistry. 10: 4954-60. PMID 22614240 DOI: 10.1039/c2ob25490e  1
2012 Slattery DA, Cryan JF. Using the rat forced swim test to assess antidepressant-like activity in rodents. Nature Protocols. 7: 1009-14. PMID 22555240 DOI: 10.1038/nprot.2012.044  1
2012 Dinan TG, Cryan JF. Regulation of the stress response by the gut microbiota: implications for psychoneuroendocrinology. Psychoneuroendocrinology. 37: 1369-78. PMID 22483040 DOI: 10.1016/j.psyneuen.2012.03.007  1
2012 Schellekens H, Clarke G, Jeffery IB, Dinan TG, Cryan JF. Dynamic 5-HT2C receptor editing in a mouse model of obesity. Plos One. 7: e32266. PMID 22448217 DOI: 10.1371/journal.pone.0032266  1
2012 Desbonnet L, O'Tuathaigh C, Clarke G, O'Leary C, Petit E, Clarke N, Tighe O, Lai D, Harvey R, Cryan JF, Dinan TG, Waddington JL. Phenotypic effects of repeated psychosocial stress during adolescence in mice mutant for the schizophrenia risk gene neuregulin-1: a putative model of gene × environment interaction. Brain, Behavior, and Immunity. 26: 660-71. PMID 22426432 DOI: 10.1016/j.bbi.2012.02.010  1
2012 Camp MC, Macpherson KP, Lederle L, Graybeal C, Gaburro S, Debrouse LM, Ihne JL, Bravo JA, O'Connor RM, Ciocchi S, Wellman CL, Lüthi A, Cryan JF, Singewald N, Holmes A. Genetic strain differences in learned fear inhibition associated with variation in neuroendocrine, autonomic, and amygdala dendritic phenotypes. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 37: 1534-47. PMID 22334122 DOI: 10.1038/npp.2011.340  1
2012 Moloney RD, O'Leary OF, Felice D, Bettler B, Dinan TG, Cryan JF. Early-life stress induces visceral hypersensitivity in mice. Neuroscience Letters. 512: 99-102. PMID 22326388 DOI: 10.1016/j.neulet.2012.01.066  1
2012 O'Brien FE, Clarke G, Fitzgerald P, Dinan TG, Griffin BT, Cryan JF. Inhibition of P-glycoprotein enhances transport of imipramine across the blood-brain barrier: microdialysis studies in conscious freely moving rats. British Journal of Pharmacology. 166: 1333-43. PMID 22250926 DOI: 10.1111/j.1476-5381.2012.01858.x  1
2012 Davey KJ, O'Mahony SM, Schellekens H, O'Sullivan O, Bienenstock J, Cotter PD, Dinan TG, Cryan JF. Gender-dependent consequences of chronic olanzapine in the rat: effects on body weight, inflammatory, metabolic and microbiota parameters. Psychopharmacology. 221: 155-69. PMID 22234378 DOI: 10.1007/s00213-011-2555-2  1
2012 Clarke G, Cryan JF, Dinan TG, Quigley EM. Review article: probiotics for the treatment of irritable bowel syndrome--focus on lactic acid bacteria. Alimentary Pharmacology & Therapeutics. 35: 403-13. PMID 22225517 DOI: 10.1111/j.1365-2036.2011.04965.x  1
2012 Browne CA, Clarke G, Dinan TG, Cryan JF. An effective dietary method for chronic tryptophan depletion in two mouse strains illuminates a role for 5-HT in nesting behaviour. Neuropharmacology. 62: 1903-15. PMID 22212181 DOI: 10.1016/j.neuropharm.2011.12.009  1
2012 O'Connor RM, Dinan TG, Cryan JF. Little things on which happiness depends: microRNAs as novel therapeutic targets for the treatment of anxiety and depression. Molecular Psychiatry. 17: 359-76. PMID 22182940 DOI: 10.1038/mp.2011.162  1
2012 O'Tuathaigh CM, Clarke G, Walsh J, Desbonnet L, Petit E, O'Leary C, Tighe O, Clarke N, Karayiorgou M, Gogos JA, Dinan TG, Cryan JF, Waddington JL. Genetic vs. pharmacological inactivation of COMT influences cannabinoid-induced expression of schizophrenia-related phenotypes. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 15: 1331-42. PMID 22074909 DOI: 10.1017/S1461145711001581  1
2012 Tramullas M, Dinan TG, Cryan JF. Chronic psychosocial stress induces visceral hyperalgesia in mice. Stress (Amsterdam, Netherlands). 15: 281-92. PMID 21992065 DOI: 10.3109/10253890.2011.622816  1
2012 Markou A, Cryan JF. Stress, anxiety and depression: toward new treatment strategies. Neuropharmacology. 62: 1-2. PMID 21983630 DOI: 10.1016/j.neuropharm.2011.09.023  1
2012 Finger BC, Dinan TG, Cryan JF. Diet-induced obesity blunts the behavioural effects of ghrelin: studies in a mouse-progressive ratio task. Psychopharmacology. 220: 173-81. PMID 21892647 DOI: 10.1007/s00213-011-2468-0  1
2012 Julio-Pieper M, O'Mahony CM, Clarke G, Bravo JA, Dinan TG, Cryan JF. Chronic stress-induced alterations in mouse colonic 5-HT and defecation responses are strain dependent. Stress (Amsterdam, Netherlands). 15: 218-26. PMID 21875301 DOI: 10.3109/10253890.2011.607524  1
2012 O'Leary OF, O'Connor RM, Cryan JF. Lithium-induced effects on adult hippocampal neurogenesis are topographically segregated along the dorso-ventral axis of stressed mice. Neuropharmacology. 62: 247-55. PMID 21803056 DOI: 10.1016/j.neuropharm.2011.07.015  1
2012 Finger BC, Dinan TG, Cryan JF. The temporal impact of chronic intermittent psychosocial stress on high-fat diet-induced alterations in body weight. Psychoneuroendocrinology. 37: 729-41. PMID 21783325 DOI: 10.1016/j.psyneuen.2011.06.015  1
2012 Kennedy PJ, Clarke G, Quigley EM, Groeger JA, Dinan TG, Cryan JF. Gut memories: towards a cognitive neurobiology of irritable bowel syndrome. Neuroscience and Biobehavioral Reviews. 36: 310-40. PMID 21777613 DOI: 10.1016/j.neubiorev.2011.07.001  1
2012 O'Brien FE, Dinan TG, Griffin BT, Cryan JF. Interactions between antidepressants and P-glycoprotein at the blood-brain barrier: clinical significance of in vitro and in vivo findings. British Journal of Pharmacology. 165: 289-312. PMID 21718296 DOI: 10.1111/j.1476-5381.2011.01557.x  1
2012 Cryan JF, Bravo JA, Dinan TG, Forsythe P, Bienenstock J. Reply to McLean et al. and Burnet: The microbiome-gut-brain axis as a pathway toward next generation psychotropics Proceedings of the National Academy of Sciences of the United States of America. 109: E176. DOI: 10.1073/pnas.1119283109  1
2012 Cryan JF, Reif A. Preface Current Topics in Behavioral Neurosciences. 12: V-VII. DOI: 10.1007/978-3-642-27859-4  1
2012 Wall R, Ross PR, Shanahan F, Quigley EM, Dinan TG, Cryan JF, Fitzgerald GF, Stanton C. Influence of gut microbiota and manipulation by probiotics and prebiotics on host tissue fat: Potential clinical implications Lipid Technology. 24: 227-229. DOI: 10.1002/lite.201200232  1
2011 McKernan DP, Dennison U, Gaszner G, Cryan JF, Dinan TG. Enhanced peripheral toll-like receptor responses in psychosis: further evidence of a pro-inflammatory phenotype. Translational Psychiatry. 1: e36. PMID 22832610 DOI: 10.1038/tp.2011.37  1
2011 Grenham S, Clarke G, Cryan JF, Dinan TG. Brain-gut-microbe communication in health and disease. Frontiers in Physiology. 2: 94. PMID 22162969 DOI: 10.3389/fphys.2011.00094  1
2011 O'Sullivan E, Barrett E, Grenham S, Fitzgerald P, Stanton C, Ross RP, Quigley EM, Cryan JF, Dinan TG. BDNF expression in the hippocampus of maternally separated rats: does Bifidobacterium breve 6330 alter BDNF levels? Beneficial Microbes. 2: 199-207. PMID 21986359 DOI: 10.3920/BM2011.0015  1
2011 Finger BC, Dinan TG, Cryan JF. Behavioral satiety sequence in a genetic mouse model of obesity: effects of ghrelin receptor ligands. Behavioural Pharmacology. 22: 624-32. PMID 21897203 DOI: 10.1097/FBP.0b013e32834afee6  1
2011 Bravo JA, Forsythe P, Chew MV, Escaravage E, Savignac HM, Dinan TG, Bienenstock J, Cryan JF. Ingestion of Lactobacillus strain regulates emotional behavior and central GABA receptor expression in a mouse via the vagus nerve. Proceedings of the National Academy of Sciences of the United States of America. 108: 16050-5. PMID 21876150 DOI: 10.1073/pnas.1102999108  1
2011 Finger BC, Dinan TG, Cryan JF. High-fat diet selectively protects against the effects of chronic social stress in the mouse. Neuroscience. 192: 351-60. PMID 21742017 DOI: 10.1016/j.neuroscience.2011.06.072  1
2011 O' Mahony SM, Coelho AM, Fitzgerald P, Lee K, Winchester W, Dinan TG, Cryan JF. The effects of gabapentin in two animal models of co-morbid anxiety and visceral hypersensitivity. European Journal of Pharmacology. 667: 169-74. PMID 21645509 DOI: 10.1016/j.ejphar.2011.05.055  1
2011 Savignac HM, Finger BC, Pizzo RC, O'Leary OF, Dinan TG, Cryan JF. Increased sensitivity to the effects of chronic social defeat stress in an innately anxious mouse strain. Neuroscience. 192: 524-36. PMID 21635938 DOI: 10.1016/j.neuroscience.2011.04.054  1
2011 O'Malley D, Dinan TG, Cryan JF. Altered expression and secretion of colonic interleukin-6 in a stress-sensitive animal model of brain-gut axis dysfunction. Journal of Neuroimmunology. 235: 48-55. PMID 21565410 DOI: 10.1016/j.jneuroim.2011.04.003  1
2011 Cryan JF, Sweeney FF. The age of anxiety: role of animal models of anxiolytic action in drug discovery. British Journal of Pharmacology. 164: 1129-61. PMID 21545412 DOI: 10.1111/j.1476-5381.2011.01362.x  1
2011 O'Malley D, Quigley EM, Dinan TG, Cryan JF. Do interactions between stress and immune responses lead to symptom exacerbations in irritable bowel syndrome? Brain, Behavior, and Immunity. 25: 1333-41. PMID 21536124 DOI: 10.1016/j.bbi.2011.04.009  1
2011 Savignac HM, Dinan TG, Cryan JF. Resistance to early-life stress in mice: effects of genetic background and stress duration. Frontiers in Behavioral Neuroscience. 5: 13. PMID 21519375 DOI: 10.3389/fnbeh.2011.00013  1
2011 McKernan DP, Gaszner G, Quigley EM, Cryan JF, Dinan TG. Altered peripheral toll-like receptor responses in the irritable bowel syndrome. Alimentary Pharmacology & Therapeutics. 33: 1045-52. PMID 21453321 DOI: 10.1111/j.1365-2036.2011.04624.x  1
2011 Finger BC, Schellekens H, Dinan TG, Cryan JF. Is there altered sensitivity to ghrelin-receptor ligands in leptin-deficient mice?: importance of satiety state and time of day. Psychopharmacology. 216: 421-9. PMID 21373788 DOI: 10.1007/s00213-011-2234-3  1
2011 Cryan JF, O'Mahony SM. The microbiome-gut-brain axis: from bowel to behavior. Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society. 23: 187-92. PMID 21303428 DOI: 10.1111/j.1365-2982.2010.01664.x  1
2011 Julio-Pieper M, Flor PJ, Dinan TG, Cryan JF. Exciting times beyond the brain: metabotropic glutamate receptors in peripheral and non-neural tissues. Pharmacological Reviews. 63: 35-58. PMID 21228260 DOI: 10.1124/pr.110.004036  1
2011 Browne CA, Clarke G, Dinan TG, Cryan JF. Differential stress-induced alterations in tryptophan hydroxylase activity and serotonin turnover in two inbred mouse strains. Neuropharmacology. 60: 683-91. PMID 21130784 DOI: 10.1016/j.neuropharm.2010.11.020  1
2011 O'Mahony CM, Clarke G, Gibney S, Dinan TG, Cryan JF. Strain differences in the neurochemical response to chronic restraint stress in the rat: relevance to depression. Pharmacology, Biochemistry, and Behavior. 97: 690-9. PMID 21110995 DOI: 10.1016/j.pbb.2010.11.012  1
2011 O'Malley D, Liston M, Hyland NP, Dinan TG, Cryan JF. Colonic soluble mediators from the maternal separation model of irritable bowel syndrome activate submucosal neurons via an interleukin-6-dependent mechanism. American Journal of Physiology. Gastrointestinal and Liver Physiology. 300: G241-52. PMID 21109592 DOI: 10.1152/ajpgi.00385.2010  1
2011 O'Mahony SM, Hyland NP, Dinan TG, Cryan JF. Maternal separation as a model of brain-gut axis dysfunction. Psychopharmacology. 214: 71-88. PMID 20886335 DOI: 10.1007/s00213-010-2010-9  1
2011 Bravo JA, Dinan TG, Cryan JF. Alterations in the central CRF system of two different rat models of comorbid depression and functional gastrointestinal disorders. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 14: 666-83. PMID 20860876 DOI: 10.1017/S1461145710000994  1
2011 Savignac HM, Hyland NP, Dinan TG, Cryan JF. The effects of repeated social interaction stress on behavioural and physiological parameters in a stress-sensitive mouse strain. Behavioural Brain Research. 216: 576-84. PMID 20826188 DOI: 10.1016/j.bbr.2010.08.049  1
2011 Slattery DA, Neumann ID, Cryan JF. Transient inactivation of the infralimbic cortex induces antidepressant-like effects in the rat. Journal of Psychopharmacology (Oxford, England). 25: 1295-303. PMID 20530589 DOI: 10.1177/0269881110368873  1
2011 O'Malley D, Dinan TG, Cryan JF. Neonatal maternal separation in the rat impacts on the stress responsivity of central corticotropin-releasing factor receptors in adulthood. Psychopharmacology. 214: 221-9. PMID 20499051 DOI: 10.1007/s00213-010-1885-9  1
2010 Hyland NP, Cryan JF. A Gut Feeling about GABA: Focus on GABA(B) Receptors. Frontiers in Pharmacology. 1: 124. PMID 21833169 DOI: 10.3389/fphar.2010.00124  1
2010 Jacobson LH, Cryan JF. Genetic approaches to modeling anxiety in animals. Current Topics in Behavioral Neurosciences. 2: 161-201. PMID 21309110 DOI: 10.1007/7854_2009_31  1
2010 Finger BC, Dinan TG, Cryan JF. Progressive ratio responding in an obese mouse model: Effects of fenfluramine. Neuropharmacology. 59: 619-26. PMID 20727362 DOI: 10.1016/j.neuropharm.2010.08.010  1
2010 Cryan JF, O'Leary OF. Neuroscience. A glutamate pathway to faster-acting antidepressants? Science (New York, N.Y.). 329: 913-4. PMID 20724626 DOI: 10.1126/science.1194313  1
2010 Desbonnet L, Garrett L, Clarke G, Kiely B, Cryan JF, Dinan TG. Effects of the probiotic Bifidobacterium infantis in the maternal separation model of depression. Neuroscience. 170: 1179-88. PMID 20696216 DOI: 10.1016/j.neuroscience.2010.08.005  1
2010 Cryan JF, Slattery DA. GABAB receptors and depression. Current status. Advances in Pharmacology (San Diego, Calif.). 58: 427-51. PMID 20655491 DOI: 10.1016/S1054-3589(10)58016-5  1
2010 O'Mahony CM, Bravo JA, Dinan TG, Cryan JF. Comparison of hippocampal metabotropic glutamate receptor 7 (mGlu7) mRNA levels in two animal models of depression. Neuroscience Letters. 482: 137-41. PMID 20638442 DOI: 10.1016/j.neulet.2010.07.018  1
2010 McKernan DP, Fitzgerald P, Dinan TG, Cryan JF. The probiotic Bifidobacterium infantis 35624 displays visceral antinociceptive effects in the rat. Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society. 22: 1029-35, e268. PMID 20518856 DOI: 10.1111/j.1365-2982.2010.01520.x  1
2010 O'Mahony CM, Sweeney FF, Daly E, Dinan TG, Cryan JF. Restraint stress-induced brain activation patterns in two strains of mice differing in their anxiety behaviour. Behavioural Brain Research. 213: 148-54. PMID 20435071 DOI: 10.1016/j.bbr.2010.04.038  1
2010 Guo J, Fisher KA, Darcy R, Cryan JF, O'Driscoll C. Therapeutic targeting in the silent era: advances in non-viral siRNA delivery. Molecular Biosystems. 6: 1143-61. PMID 20431817 DOI: 10.1039/c001050m  1
2010 Julio-Pieper M, Hyland NP, Bravo JA, Dinan TG, Cryan JF. A novel role for the metabotropic glutamate receptor-7: modulation of faecal water content and colonic electrolyte transport in the mouse. British Journal of Pharmacology. 160: 367-75. PMID 20423346 DOI: 10.1111/j.1476-5381.2010.00713.x  1
2010 Finger BC, Dinan TG, Cryan JF. Leptin-deficient mice retain normal appetitive spatial learning yet exhibit marked increases in anxiety-related behaviours. Psychopharmacology. 210: 559-68. PMID 20422404 DOI: 10.1007/s00213-010-1858-z  1
2010 O'Connor RM, Finger BC, Flor PJ, Cryan JF. Metabotropic glutamate receptor 7: at the interface of cognition and emotion. European Journal of Pharmacology. 639: 123-31. PMID 20371242 DOI: 10.1016/j.ejphar.2010.02.059  1
2010 Gosselin RD, O'Connor RM, Tramullas M, Julio-Pieper M, Dinan TG, Cryan JF. Riluzole normalizes early-life stress-induced visceral hypersensitivity in rats: role of spinal glutamate reuptake mechanisms. Gastroenterology. 138: 2418-25. PMID 20226190 DOI: 10.1053/j.gastro.2010.03.003  1
2010 O'Malley D, Julio-Pieper M, Gibney SM, Dinan TG, Cryan JF. Distinct alterations in colonic morphology and physiology in two rat models of enhanced stress-induced anxiety and depression-like behaviour. Stress (Amsterdam, Netherlands). 13: 114-22. PMID 20214436 DOI: 10.3109/10253890903067418  1
2010 O'Malley D, Dinan TG, Cryan JF. Alterations in colonic corticotropin-releasing factor receptors in the maternally separated rat model of irritable bowel syndrome: differential effects of acute psychological and physical stressors. Peptides. 31: 662-70. PMID 20096320 DOI: 10.1016/j.peptides.2010.01.004  1
2010 Levav-Rabkin T, Melamed O, Clarke G, Farber M, Cryan JF, Dinan TG, Grossman Y, Golan HM. A sensitive period of mice inhibitory system to neonatal GABA enhancement by vigabatrin is brain region dependent. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 35: 1138-54. PMID 20043003 DOI: 10.1038/npp.2009.219  1
2010 O'Mahony SM, Bulmer DC, Coelho AM, Fitzgerald P, Bongiovanni C, Lee K, Winchester W, Dinan TG, Cryan JF. 5-HT(2B) receptors modulate visceral hypersensitivity in a stress-sensitive animal model of brain-gut axis dysfunction. Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society. 22: 573-8, e124. PMID 20003079 DOI: 10.1111/j.1365-2982.2009.01432.x  1
2010 Clarke G, Fitzgerald P, Hennessy AA, Cassidy EM, Quigley EM, Ross P, Stanton C, Cryan JF, Dinan TG. Marked elevations in pro-inflammatory polyunsaturated fatty acid metabolites in females with irritable bowel syndrome. Journal of Lipid Research. 51: 1186-92. PMID 19965606 DOI: 10.1194/jlr.P000695  1
2010 o'malley D, Julio-Pieper M, Gibney SM, Gosselin RD, Dinan TG, Cryan JF. Differential stress-induced alterations of colonic corticotropin-releasing factor receptors in the Wistar Kyoto rat. Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society. 22: 301-11. PMID 19807869 DOI: 10.1111/j.1365-2982.2009.01412.x  1
2010 Gibney SM, Gosselin RD, Dinan TG, Cryan JF. Colorectal distension-induced prefrontal cortex activation in the Wistar-Kyoto rat: implications for irritable bowel syndrome. Neuroscience. 165: 675-83. PMID 19765638 DOI: 10.1016/j.neuroscience.2009.08.076  1
2010 Schellekens H, Dinan TG, Cryan JF. Lean mean fat reducing "ghrelin" machine: hypothalamic ghrelin and ghrelin receptors as therapeutic targets in obesity. Neuropharmacology. 58: 2-16. PMID 19573543 DOI: 10.1016/j.neuropharm.2009.06.024  1
2010 Cryan JF, Leonard BE. Depression: From psychopathology to pharmacotherapy Depression: From Psychopathology to Pharmacotherapy. 27: 1-274. DOI: 10.1159/isbn.978-3-8055-9606-0  1
2010 Cryan JF, Leonard BE. Modern Trends in Pharmacopsychiatry: Preface Modern Trends in Pharmacopsychiatry. 27: VII-VIII. DOI: 10.1159/000320280  1
2010 Slattery DA, Cryan JF. Animal models of depression - Where are we going? Modern Trends in Pharmacopsychiatry. 27: 124-138. DOI: 10.1159/000319511  1
2010 O’Connor RM, Cryan JF. Role of metabotropic glutamate receptors in CNS disorders G Protein-Coupled Receptors: Structure, Signaling, and Physiology. 321-379. DOI: 10.1017/CBO9780511760334.017  1
2010 Vinkers CH, Cryan JF, Olivier B, Groenink L. Elucidating GABAA and GABAB receptor functions in anxiety using the stress-induced hyperthermia paradigm: A review Open Pharmacology Journal. 4: 1-14.  1
2009 McKernan DP, Nolan A, Brint EK, O'Mahony SM, Hyland NP, Cryan JF, Dinan TG. Toll-like receptor mRNA expression is selectively increased in the colonic mucosa of two animal models relevant to irritable bowel syndrome. Plos One. 4: e8226. PMID 20011045 DOI: 10.1371/journal.pone.0008226  1
2009 Clarke G, Quigley EM, Cryan JF, Dinan TG. Irritable bowel syndrome: towards biomarker identification. Trends in Molecular Medicine. 15: 478-89. PMID 19811951 DOI: 10.1016/j.molmed.2009.08.001  1
2009 Clarke G, O'Mahony SM, Hennessy AA, Ross P, Stanton C, Cryan JF, Dinan TG. Chain reactions: early-life stress alters the metabolic profile of plasma polyunsaturated fatty acids in adulthood. Behavioural Brain Research. 205: 319-21. PMID 19616034 DOI: 10.1016/j.bbr.2009.07.008  1
2009 Casanova E, Guetg N, Vigot R, Seddik R, Julio-Pieper M, Hyland NP, Cryan JF, Gassmann M, Bettler B. A mouse model for visualization of GABA(B) receptors. Genesis (New York, N.Y. : 2000). 47: 595-602. PMID 19603512 DOI: 10.1002/dvg.20535  1
2009 Hyland NP, Julio-Pieper M, O'Mahony SM, Bulmer DC, Lee K, Quigley EM, Dinan TG, Cryan JF. A distinct subset of submucosal mast cells undergoes hyperplasia following neonatal maternal separation: a role in visceral hypersensitivity? Gut. 58: 1029-30; author repl. PMID 19520896 DOI: 10.1136/gut.2008.167882  1
2009 McKernan DP, Dinan TG, Cryan JF. "Killing the Blues": a role for cellular suicide (apoptosis) in depression and the antidepressant response? Progress in Neurobiology. 88: 246-63. PMID 19427352 DOI: 10.1016/j.pneurobio.2009.04.006  1
2009 Glynn DA, Cryan JF, Kent P, Flynn RA, Kennedy MP. Update on smoking cessation therapies. Advances in Therapy. 26: 369-82. PMID 19399385 DOI: 10.1007/s12325-009-0022-9  1
2009 Clarke G, O'Mahony SM, Cryan JF, Dinan TG. Verapamil in treatment resistant depression: a role for the P-glycoprotein transporter? Human Psychopharmacology. 24: 217-23. PMID 19212940 DOI: 10.1002/hup.1008  1
2009 Clarke G, Fitzgerald P, Cryan JF, Cassidy EM, Quigley EM, Dinan TG. Tryptophan degradation in irritable bowel syndrome: evidence of indoleamine 2,3-dioxygenase activation in a male cohort. Bmc Gastroenterology. 9: 6. PMID 19154614 DOI: 10.1186/1471-230X-9-6  1
2009 Gosselin RD, Gibney S, O'Malley D, Dinan TG, Cryan JF. Region specific decrease in glial fibrillary acidic protein immunoreactivity in the brain of a rat model of depression. Neuroscience. 159: 915-25. PMID 19000745 DOI: 10.1016/j.neuroscience.2008.10.018  1
2009 O'Mahony SM, Marchesi JR, Scully P, Codling C, Ceolho AM, Quigley EM, Cryan JF, Dinan TG. Early life stress alters behavior, immunity, and microbiota in rats: implications for irritable bowel syndrome and psychiatric illnesses. Biological Psychiatry. 65: 263-7. PMID 18723164 DOI: 10.1016/j.biopsych.2008.06.026  1
2009 O'Leary OF, Cryan JF. The tail-suspension test: A model for characterizing antidepressant activity in mice Neuromethods. 42: 119-137. DOI: 10.1007/978-1-60761-303-9-7  1
2008 Stachowicz K, Brañski P, KÅ‚ak K, van der Putten H, Cryan JF, Flor PJ, Andrzej P. Selective activation of metabotropic G-protein-coupled glutamate 7 receptor elicits anxiolytic-like effects in mice by modulating GABAergic neurotransmission. Behavioural Pharmacology. 19: 597-603. PMID 18690114 DOI: 10.1097/FBP.0b013e32830cd839  1
2008 Jacobson LH, Cryan JF. Evaluation of the anxiolytic-like profile of the GABAB receptor positive modulator CGP7930 in rodents. Neuropharmacology. 54: 854-62. PMID 18328507 DOI: 10.1016/j.neuropharm.2008.01.004  1
2008 Bissière S, Plachta N, Hoyer D, McAllister KH, Olpe HR, Grace AA, Cryan JF. The rostral anterior cingulate cortex modulates the efficiency of amygdala-dependent fear learning. Biological Psychiatry. 63: 821-31. PMID 18155183 DOI: 10.1016/j.biopsych.2007.10.022  1
2008 Fendt M, Schmid S, Thakker DR, Jacobson LH, Yamamoto R, Mitsukawa K, Maier R, Natt F, Hüsken D, Kelly PH, McAllister KH, Hoyer D, van der Putten H, Cryan JF, Flor PJ. mGluR7 facilitates extinction of aversive memories and controls amygdala plasticity. Molecular Psychiatry. 13: 970-9. PMID 17712315 DOI: 10.1038/sj.mp.4002073  1
2008 Cryan JF, Dev KK. Chapter 4.4 The glutamatergic system as a potential therapeutic target for the treatment of anxiety disorders Handbook of Behavioral Neuroscience. 17: 269-301. DOI: 10.1016/S1569-7339(07)00013-6  1
2008 Cryan JF, Sánchez C, Dinan TG, Borsini F. Developing more efficacious antidepressant medications: Improving and aligning preclinical and clinical assessment tools Animal and Translational Models For Cns Drug Discovery. 1: 165-197. DOI: 10.1016/B978-0-12-373861-5.00007-2  1
2007 Senechal Y, Kelly PH, Cryan JF, Natt F, Dev KK. Amyloid precursor protein knockdown by siRNA impairs spontaneous alternation in adult mice. Journal of Neurochemistry. 102: 1928-40. PMID 17540010 DOI: 10.1111/j.1471-4159.2007.04672.x  1
2007 Jacobson LH, Kelly PH, Bettler B, Kaupmann K, Cryan JF. Specific roles of GABA(B(1)) receptor isoforms in cognition. Behavioural Brain Research. 181: 158-62. PMID 17498817 DOI: 10.1016/j.bbr.2007.03.033  1
2007 Cryan JF, Thakker DR, Hoyer D. Emerging use of non-viral RNA interference in the brain. Biochemical Society Transactions. 35: 411-5. PMID 17371288 DOI: 10.1042/BST0350411  1
2007 Rosenzweig-Lipson S, Sabb A, Stack G, Mitchell P, Lucki I, Malberg JE, Grauer S, Brennan J, Cryan JF, Sukoff Rizzo SJ, Dunlop J, Barrett JE, Marquis KL. Antidepressant-like effects of the novel, selective, 5-HT2C receptor agonist WAY-163909 in rodents. Psychopharmacology. 192: 159-70. PMID 17297636 DOI: 10.1007/s00213-007-0710-6  1
2007 Mombereau C, Lhuillier L, Kaupmann K, Cryan JF. GABAB receptor-positive modulation-induced blockade of the rewarding properties of nicotine is associated with a reduction in nucleus accumbens DeltaFosB accumulation. The Journal of Pharmacology and Experimental Therapeutics. 321: 172-7. PMID 17215447 DOI: 10.1124/jpet.106.116228  1
2007 Slattery DA, Markou A, Cryan JF. Evaluation of reward processes in an animal model of depression. Psychopharmacology. 190: 555-68. PMID 17177055 DOI: 10.1007/s00213-006-0630-x  1
2007 Jacobson LH, Bettler B, Kaupmann K, Cryan JF. Behavioral evaluation of mice deficient in GABA(B(1)) receptor isoforms in tests of unconditioned anxiety. Psychopharmacology. 190: 541-53. PMID 17171558 DOI: 10.1007/s00213-006-0631-9  1
2007 Cryan JF, Driscoll P, Waddington JL. Neurogenetics and behaviour: From basic processes to neuropsychiatric disorders Neuroscience and Biobehavioral Reviews. 31: 1-2. PMID 17156842 DOI: 10.1016/j.neubiorev.2006.10.005  1
2007 Cryan JF, Slattery DA. Animal models of mood disorders: Recent developments. Current Opinion in Psychiatry. 20: 1-7. PMID 17143074 DOI: 10.1097/YCO.0b013e3280117733  1
2007 Jacobson LH, Cryan JF. Feeling strained? Influence of genetic background on depression-related behavior in mice: a review. Behavior Genetics. 37: 171-213. PMID 17029009 DOI: 10.1007/s10519-006-9106-3  1
2007 Lhuillier L, Mombereau C, Cryan JF, Kaupmann K. GABA(B) receptor-positive modulation decreases selective molecular and behavioral effects of cocaine. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 32: 388-98. PMID 16710312 DOI: 10.1038/sj.npp.1301102  1
2006 Hoyer D, Thakker DR, Natt F, Maier R, Huesken D, Müller M, Flor P, VAN DER Putten H, Schmutz M, Bilbe G, Cryan JF. Global down-regulation of gene expression in the brain using RNA interference, with emphasis on monoamine transporters and GPCRs: implications for target characterization in psychiatric and neurological disorders. Journal of Receptor and Signal Transduction Research. 26: 527-47. PMID 17118797 DOI: 10.1080/10799890600929663  1
2006 Bissiere S, McAllister KH, Olpe HR, Cryan JF. The rostral anterior cingulate cortex modulates depression but not anxiety-related behaviour in the rat. Behavioural Brain Research. 175: 195-9. PMID 17018236 DOI: 10.1016/j.bbr.2006.08.022  1
2006 Jacobson LH, Bettler B, Kaupmann K, Cryan JF. GABAB1 receptor subunit isoforms exert a differential influence on baseline but not GABAB receptor agonist-induced changes in mice. The Journal of Pharmacology and Experimental Therapeutics. 319: 1317-26. PMID 16990508 DOI: 10.1124/jpet.106.111971  1
2006 Jacobson LH, Kelly PH, Bettler B, Kaupmann K, Cryan JF. GABA(B(1)) receptor isoforms differentially mediate the acquisition and extinction of aversive taste memories. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 8800-3. PMID 16928868 DOI: 10.1523/JNEUROSCI.2076-06.2006  1
2006 Callaerts-Vegh Z, Beckers T, Ball SM, Baeyens F, Callaerts PF, Cryan JF, Molnar E, D'Hooge R. Concomitant deficits in working memory and fear extinction are functionally dissociated from reduced anxiety in metabotropic glutamate receptor 7-deficient mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 6573-82. PMID 16775145 DOI: 10.1523/JNEUROSCI.1497-06.2006  1
2006 Vigot R, Barbieri S, Bräuner-Osborne H, Turecek R, Shigemoto R, Zhang YP, Luján R, Jacobson LH, Biermann B, Fritschy JM, Vacher CM, Müller M, Sansig G, Guetg N, Cryan JF, et al. Differential compartmentalization and distinct functions of GABAB receptor variants. Neuron. 50: 589-601. PMID 16701209 DOI: 10.1016/j.neuron.2006.04.014  1
2006 Mitsukawa K, Mombereau C, Lötscher E, Uzunov DP, van der Putten H, Flor PJ, Cryan JF. Metabotropic glutamate receptor subtype 7 ablation causes dysregulation of the HPA axis and increases hippocampal BDNF protein levels: implications for stress-related psychiatric disorders. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 31: 1112-22. PMID 16237391 DOI: 10.1038/sj.npp.1300926  1
2006 Thakker DR, Hoyer D, Cryan JF. Interfering with the brain: use of RNA interference for understanding the pathophysiology of psychiatric and neurological disorders. Pharmacology & Therapeutics. 109: 413-38. PMID 16183135 DOI: 10.1016/j.pharmthera.2005.08.006  1
2006 Slattery DA, Cryan JF. The role of GABAB receptors in depression and antidepressant-related behavioural responses Drug Development Research. 67: 477-494. DOI: 10.1002/ddr.20110  1
2005 Mitsukawa K, Yamamoto R, Ofner S, Nozulak J, Pescott O, Lukic S, Stoehr N, Mombereau C, Kuhn R, McAllister KH, van der Putten H, Cryan JF, Flor PJ. A selective metabotropic glutamate receptor 7 agonist: activation of receptor signaling via an allosteric site modulates stress parameters in vivo. Proceedings of the National Academy of Sciences of the United States of America. 102: 18712-7. PMID 16339898 DOI: 10.1073/pnas.0508063102  1
2005 Cryan JF, Holmes A. The ascent of mouse: advances in modelling human depression and anxiety. Nature Reviews. Drug Discovery. 4: 775-90. PMID 16138108 DOI: 10.1038/nrd1825  1
2005 Cryan JF, Page ME, Lucki I. Differential behavioral effects of the antidepressants reboxetine, fluoxetine, and moclobemide in a modified forced swim test following chronic treatment. Psychopharmacology. 182: 335-44. PMID 16001105 DOI: 10.1007/s00213-005-0093-5  1
2005 Thakker DR, Natt F, Hüsken D, van der Putten H, Maier R, Hoyer D, Cryan JF. siRNA-mediated knockdown of the serotonin transporter in the adult mouse brain. Molecular Psychiatry. 10: 782-9, 714. PMID 15940298 DOI: 10.1038/sj.mp.4001687  1
2005 Cryan JF, Valentino RJ, Lucki I. Assessing substrates underlying the behavioral effects of antidepressants using the modified rat forced swimming test. Neuroscience and Biobehavioral Reviews. 29: 547-69. PMID 15893822 DOI: 10.1016/j.neubiorev.2005.03.008  1
2005 Cryan JF, Mombereau C, Vassout A. The tail suspension test as a model for assessing antidepressant activity: review of pharmacological and genetic studies in mice. Neuroscience and Biobehavioral Reviews. 29: 571-625. PMID 15890404 DOI: 10.1016/j.neubiorev.2005.03.009  1
2005 Slattery DA, Markou A, Froestl W, Cryan JF. The GABAB receptor-positive modulator GS39783 and the GABAB receptor agonist baclofen attenuate the reward-facilitating effects of cocaine: intracranial self-stimulation studies in the rat. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 30: 2065-72. PMID 15841108 DOI: 10.1038/sj.npp.1300734  1
2005 Page ME, Szeliga P, Gasparini F, Cryan JF. Blockade of the mGlu5 receptor decreases basal and stress-induced cortical norepinephrine in rodents. Psychopharmacology. 179: 240-6. PMID 15717212 DOI: 10.1007/s00213-005-2142-5  1
2005 Mombereau C, Kaupmann K, Gassmann M, Bettler B, van der Putten H, Cryan JF. Altered anxiety and depression-related behaviour in mice lacking GABAB(2) receptor subunits. Neuroreport. 16: 307-10. PMID 15706241 DOI: 10.1097/00001756-200502280-00021  1
2005 Jacobson LH, Cryan JF. Differential sensitivity to the motor and hypothermic effects of the GABA B receptor agonist baclofen in various mouse strains. Psychopharmacology. 179: 688-99. PMID 15668819 DOI: 10.1007/s00213-004-2086-1  1
2005 Cryan JF, Kaupmann K. Don't worry 'B' happy!: a role for GABA(B) receptors in anxiety and depression. Trends in Pharmacological Sciences. 26: 36-43. PMID 15629203 DOI: 10.1016/j.tips.2004.11.004  1
2005 Slattery DA, Desrayaud S, Cryan JF. GABAB receptor antagonist-mediated antidepressant-like behavior is serotonin-dependent. The Journal of Pharmacology and Experimental Therapeutics. 312: 290-6. PMID 15333677 DOI: 10.1124/jpet.104.073536  1
2004 Thakker DR, Natt F, Hüsken D, Maier R, Müller M, van der Putten H, Hoyer D, Cryan JF. Neurochemical and behavioral consequences of widespread gene knockdown in the adult mouse brain by using nonviral RNA interference. Proceedings of the National Academy of Sciences of the United States of America. 101: 17270-5. PMID 15569935 DOI: 10.1073/pnas.0406214101  1
2004 Mombereau C, Kaupmann K, van der Putten H, Cryan JF. Altered response to benzodiazepine anxiolytics in mice lacking GABA B(1) receptors. European Journal of Pharmacology. 497: 119-20. PMID 15321743 DOI: 10.1016/j.ejphar.2004.06.036  1
2004 Gassmann M, Shaban H, Vigot R, Sansig G, Haller C, Barbieri S, Humeau Y, Schuler V, Müller M, Kinzel B, Klebs K, Schmutz M, Froestl W, Heid J, Kelly PH, ... ... Cryan JF, et al. Redistribution of GABAB(1) protein and atypical GABAB responses in GABAB(2)-deficient mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 6086-97. PMID 15240800 DOI: 10.1523/JNEUROSCI.5635-03.2004  1
2004 Cryan JF, O'Leary OF, Jin SH, Friedland JC, Ouyang M, Hirsch BR, Page ME, Dalvi A, Thomas SA, Lucki I. Norepinephrine-deficient mice lack responses to antidepressant drugs, including selective serotonin reuptake inhibitors. Proceedings of the National Academy of Sciences of the United States of America. 101: 8186-91. PMID 15148402 DOI: 10.1073/pnas.0401080101  1
2004 Cryan JF, Kelly PH, Chaperon F, Gentsch C, Mombereau C, Lingenhoehl K, Froestl W, Bettler B, Kaupmann K, Spooren WP. Behavioral characterization of the novel GABAB receptor-positive modulator GS39783 (N,N'-dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine): anxiolytic-like activity without side effects associated with baclofen or benzodiazepines. The Journal of Pharmacology and Experimental Therapeutics. 310: 952-63. PMID 15113848 DOI: 10.1124/jpet.104.066753  1
2004 Mombereau C, Kaupmann K, Froestl W, Sansig G, van der Putten H, Cryan JF. Genetic and pharmacological evidence of a role for GABA(B) receptors in the modulation of anxiety- and antidepressant-like behavior. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 29: 1050-62. PMID 15039762 DOI: 10.1038/sj.npp.1300413  1
2004 Cryan JF, Mombereau C. In search of a depressed mouse: utility of models for studying depression-related behavior in genetically modified mice. Molecular Psychiatry. 9: 326-57. PMID 14743184 DOI: 10.1038/sj.mp.4001457  1
2003 Cryan JF, Gasparini F, van Heeke G, Markou A. Non-nicotinic neuropharmacological strategies for nicotine dependence: beyond bupropion. Drug Discovery Today. 8: 1025-34. PMID 14690633 DOI: 10.1016/S1359-6446(03)02890-3  1
2003 Kaupmann K, Cryan JF, Wellendorph P, Mombereau C, Sansig G, Klebs K, Schmutz M, Froestl W, van der Putten H, Mosbacher J, Bräuner-Osborne H, Waldmeier P, Bettler B. Specific gamma-hydroxybutyrate-binding sites but loss of pharmacological effects of gamma-hydroxybutyrate in GABA(B)(1)-deficient mice. The European Journal of Neuroscience. 18: 2722-30. PMID 14656321 DOI: 10.1111/j.1460-9568.2003.03013.x  1
2003 Cryan JF, Hoyer D, Markou A. Withdrawal from chronic amphetamine induces depressive-like behavioral effects in rodents. Biological Psychiatry. 54: 49-58. PMID 12842308 DOI: 10.1016/S0006-3223(02)01730-4  1
2003 Cryan JF, Kelly PH, Neijt HC, Sansig G, Flor PJ, van Der Putten H. Antidepressant and anxiolytic-like effects in mice lacking the group III metabotropic glutamate receptor mGluR7. The European Journal of Neuroscience. 17: 2409-17. PMID 12814372  0.76
2003 Cryan JF, Bruijnzeel AW, Skjei KL, Markou A. Bupropion enhances brain reward function and reverses the affective and somatic aspects of nicotine withdrawal in the rat. Psychopharmacology. 168: 347-58. PMID 12698231 DOI: 10.1007/s00213-003-1445-7  1
2002 Page ME, Cryan JF, Sullivan A, Dalvi A, Saucy B, Manning DR, Lucki I. Behavioral and neurochemical effects of 5-(4-[4-(5-Cyano-3-indolyl)-butyl)-butyl]-1-piperazinyl)-benzofuran-2-carboxamide (EMD 68843): a combined selective inhibitor of serotonin reuptake and 5-hydroxytryptamine(1A) receptor partial agonist. The Journal of Pharmacology and Experimental Therapeutics. 302: 1220-7. PMID 12183683 DOI: 10.1124/jpet.102.034280  1
2002 Cryan JF, Markou A, Lucki I. Assessing antidepressant activity in rodents: recent developments and future needs. Trends in Pharmacological Sciences. 23: 238-45. PMID 12008002 DOI: 10.1016/S0165-6147(02)02017-5  1
2002 Conti AC, Cryan JF, Dalvi A, Lucki I, Blendy JA. cAMP response element-binding protein is essential for the upregulation of brain-derived neurotrophic factor transcription, but not the behavioral or endocrine responses to antidepressant drugs. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 3262-8. PMID 11943827  1
2002 Cryan JF, Page ME, Lucki I. Noradrenergic lesions differentially alter the antidepressant-like effects of reboxetine in a modified forced swim test. European Journal of Pharmacology. 436: 197-205. PMID 11858799 DOI: 10.1016/S0014-2999(01)01628-4  1
2001 Cryan JF, Dalvi A, Jin SH, Hirsch BR, Lucki I, Thomas SA. Use of dopamine-beta-hydroxylase-deficient mice to determine the role of norepinephrine in the mechanism of action of antidepressant drugs. The Journal of Pharmacology and Experimental Therapeutics. 298: 651-7. PMID 11454927  1
2000 Cryan JF, Leonard BE. 5-HT1A and beyond: the role of serotonin and its receptors in depression and the antidepressant response. Human Psychopharmacology. 15: 113-135. PMID 12404340 DOI: 10.1002/(SICI)1099-1077(200003)15:2<113::AID-HUP150>3.0.CO;2-W  1
2000 Olver JS, Cryan JF, Burrows GD, Norman TR. Pindolol augmentation of antidepressants: a review and rationale. The Australian and New Zealand Journal of Psychiatry. 34: 71-9. PMID 11185947 DOI: 10.1046/j.1440-1614.2000.00681.x  1
2000 Cryan JF, Lucki I. 5-HT4 receptors do not mediate the antidepressant-like behavioral effects of fluoxetine in a modified forced swim test. European Journal of Pharmacology. 409: 295-9. PMID 11108824 DOI: 10.1016/S0014-2999(00)00858-X  1
2000 Cryan JF, Lucki I. Antidepressant-like behavioral effects mediated by 5-Hydroxytryptamine(2C) receptors. The Journal of Pharmacology and Experimental Therapeutics. 295: 1120-6. PMID 11082448  1
2000 Cryan JF, Harkin A, Naughton M, Kelly JP, Leonard BE. Characterization of D-fenfluramine-induced hypothermia: evidence for multiple sites of action. European Journal of Pharmacology. 390: 275-85. PMID 10708734 DOI: 10.1016/S0014-2999(00)00012-1  1
1999 Cryan JF, Kelliher P, Kelly JP, Leonard BE. Comparative effects of serotonergic agonists with varying efficacy at the 5-HT(1A) receptor on core body temperature: modification by the selective 5-HT(1A) receptor antagonist WAY 100635. Journal of Psychopharmacology (Oxford, England). 13: 278-83. PMID 10512084  1
1999 Healy DG, Harkin A, Cryan JF, Kelly JP, Leonard BE. Metyrapone displays antidepressant-like properties in preclinical paradigms. Psychopharmacology. 145: 303-8. PMID 10494579 DOI: 10.1007/s002130051062  1
1999 Cryan JF, McGrath C, Leonard BE, Norman TR. Onset of the effects of the 5-HT1A antagonist, WAY-100635, alone, and in combination with paroxetine, on olfactory bulbectomy and 8-OH-DPAT-induced changes in the rat. Pharmacology, Biochemistry, and Behavior. 63: 333-8. PMID 10371664 DOI: 10.1016/S0091-3057(98)00245-7  1
1998 Cryan JF, McGrath C, Leonard BE, Norman TR. Combining pindolol and paroxetine in an animal model of chronic antidepressant action--can early onset of action be detected? European Journal of Pharmacology. 352: 23-8. PMID 9718263 DOI: 10.1016/S0014-2999(98)00402-6  1
1997 Cryan JF, Redmond AM, Kelly JP, Leonard BE. The effects of the 5-HT1A agonist flesinoxan, in three paradigms for assessing antidepressant potential in the rat. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 7: 109-14. PMID 9169298 DOI: 10.1016/S0924-977X(96)00391-4  1
1996 Cryan JF, Redmond AM, Kelly JP, Leonard BE. Does the serenic eltoprazine have antidepressant potential? - An investigation in three rodent paradigms Medical Science Research. 24: 719-720.  1
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