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Micah T. McClain, Ph.D. - Publications

Affiliations: 
2002 University of Oklahoma Health Sciences Center, Oklahoma City, OK, United States 
Area:
Immunology, Pathology
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45/111 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Steinbrink JM, Zaas AK, Betancourt M, Modliszewski JL, Corcoran DL, McClain MT. A transcriptional signature accurately identifies Aspergillus Infection across healthy and immunosuppressed states. Translational Research : the Journal of Laboratory and Clinical Medicine. PMID 32165060 DOI: 10.1016/J.Trsl.2020.02.005  0.314
2019 Lydon EC, Henao R, Burke TW, Aydin M, Nicholson BP, Glickman SW, Fowler VG, Quackenbush EB, Cairns CB, Kingsmore SF, Jaehne AK, Rivers EP, Langley RJ, Petzold E, Ko ER, ... McClain MT, et al. Validation of a host response test to distinguish bacterial and viral respiratory infection. Ebiomedicine. PMID 31631046 DOI: 10.1016/J.Ebiom.2019.09.040  0.31
2019 Jog NR, McClain MT, Heinlen LD, Gross T, Towner R, Guthridge JM, Axtell RC, Pardo G, Harley JB, James JA. Epstein Barr virus nuclear antigen 1 (EBNA-1) peptides recognized by adult multiple sclerosis patient sera induce neurologic symptoms in a murine model. Journal of Autoimmunity. 102332. PMID 31515129 DOI: 10.1016/J.Jaut.2019.102332  0.784
2019 Khan K, Betancourt-Quiroz M, Zaas AK, Treece AE, Que LG, Henao R, Suchindran S, McClain MT, Woods CW, Ginsburg GS, Tsalik EL, Tsalik EL. 2595. Murine Models for the Host Response to Typical and Atypical Pneumonia Open Forum Infectious Diseases. 6: S902-S902. DOI: 10.1093/Ofid/Ofz360.2273  0.34
2019 Steinbrink JM, Zaas AK, Βncourt-Quiroz M, Modliszewski JL, Corcoran D, McClain MT. 1721. A Transcriptional Signature of Acute Aspergillus Infection Offers High Diagnostic Accuracy Despite the Presence of Immunosuppression Open Forum Infectious Diseases. 6: S630-S631. DOI: 10.1093/Ofid/Ofz360.1584  0.317
2019 Steinbrink JM, Hua K, Myers R, Johnson MD, Seidelman J, Tsalik EL, Tsalik EL, Alexander BD, McClain MT. 2885. A Host Transcriptional Signature for Accurate Diagnosis of Candidemia in the Hospital Setting Open Forum Infectious Diseases. 6: S76-S76. DOI: 10.1093/Ofid/Ofz359.163  0.344
2018 Fourati S, Talla A, Mahmoudian M, Burkhart JG, Klén R, Henao R, Yu T, Aydın Z, Yeung KY, Ahsen ME, Almugbel R, Jahandideh S, Liang X, Nordling TEM, Shiga M, ... ... McClain MT, et al. A crowdsourced analysis to identify ab initio molecular signatures predictive of susceptibility to viral infection. Nature Communications. 9: 4418. PMID 30356117 DOI: 10.1038/S41467-018-06735-8  0.3
2017 Burke TW, Henao R, Soderblom E, Tsalik EL, Thompson JW, McClain MT, Nichols M, Nicholson BP, Veldman T, Lucas JE, Moseley MA, Turner RB, Lambkin-Williams R, Hero AO, Woods CW, et al. Nasopharyngeal Protein Biomarkers of Acute Respiratory Virus Infection. Ebiomedicine. PMID 28238698 DOI: 10.1016/J.Ebiom.2017.02.015  0.327
2016 Holcomb ZE, Tsalik EL, Woods CW, McClain MT. Host-based Peripheral Blood Gene Expression Analysis for the Diagnosis of Infectious Diseases. Journal of Clinical Microbiology. PMID 27795332 DOI: 10.1128/Jcm.01057-16  0.316
2016 McClain MT, Nicholson BP, Park LP, Liu TY, Hero AO, Tsalik EL, Zaas AK, Veldman T, Hudson LL, Lambkin-Williams R, Gilbert A, Burke T, Nichols M, Ginsburg GS, Woods CW. A Genomic Signature of Influenza Infection Shows Potential for Presymptomatic Detection, Guiding Early Therapy, and Monitoring Clinical Responses. Open Forum Infectious Diseases. 3: ofw007. PMID 26933666 DOI: 10.1093/Ofid/Ofw007  0.333
2016 Tsalik EL, Henao R, Nichols M, Burke T, Ko ER, McClain MT, Hudson LL, Mazur A, Freeman DH, Veldman T, Langley RJ, Quackenbush EB, Glickman SW, Cairns CB, Jaehne AK, et al. Host gene expression classifiers diagnose acute respiratory illness etiology. Science Translational Medicine. 8: 322ra11. PMID 26791949 DOI: 10.1126/Scitranslmed.Aad6873  0.311
2015 Tsalik EL, Li Y, Hudson LL, Chu VH, Himmel T, Limkakeng AT, Katz JN, Glickman SW, McClain MT, Welty-Wolf KE, Fowler VG, Ginsburg GS, Woods CW, Reed SD. Potential Cost-effectiveness of Early Identification of Hospital-acquired Infection in Critically Ill Patients. Annals of the American Thoracic Society. PMID 26700878 DOI: 10.1513/Annalsats.201504-205Oc  0.301
2015 McClain MT, Henao R, Williams J, Nicholson B, Veldman T, Hudson L, Tsalik EL, Lambkin-Williams R, Gilbert A, Mann A, Ginsburg GS, Woods CW. Differential evolution of peripheral cytokine levels in symptomatic and asymptomatic responses to experimental influenza virus challenge. Clinical and Experimental Immunology. PMID 26506932 DOI: 10.1111/Cei.12736  0.316
2015 Ko ER, Yang WE, McClain MT, Woods CW, Ginsburg GS, Tsalik EL. What was old is new again: using the host response to diagnose infectious disease. Expert Review of Molecular Diagnostics. 1-16. PMID 26145249 DOI: 10.1586/14737159.2015.1059278  0.308
2014 Tsalik EL, Langley RJ, Dinwiddie DL, Miller NA, Yoo B, van Velkinburgh JC, Smith LD, Thiffault I, Jaehne AK, Valente AM, Henao R, Yuan X, Glickman SW, Rice BJ, McClain MT, et al. An integrated transcriptome and expressed variant analysis of sepsis survival and death. Genome Medicine. 6: 111. PMID 25538794 DOI: 10.1186/S13073-014-0111-5  0.318
2013 McClain MT, Park LP, Nicholson B, Veldman T, Zaas AK, Turner R, Lambkin-Williams R, Gilbert AS, Ginsburg GS, Woods CW. Longitudinal analysis of leukocyte differentials in peripheral blood of patients with acute respiratory viral infections. Journal of Clinical Virology : the Official Publication of the Pan American Society For Clinical Virology. 58: 689-95. PMID 24140015 DOI: 10.1016/J.Jcv.2013.09.015  0.329
2013 Zaas AK, Burke T, Chen M, McClain M, Nicholson B, Veldman T, Tsalik EL, Fowler V, Rivers EP, Otero R, Kingsmore SF, Voora D, Lucas J, Hero AO, Carin L, et al. A host-based RT-PCR gene expression signature to identify acute respiratory viral infection. Science Translational Medicine. 5: 203ra126. PMID 24048524 DOI: 10.1126/Scitranslmed.3006280  0.303
2013 Bagga B, Woods CW, Veldman TH, Gilbert A, Mann A, Balaratnam G, Lambkin-Williams R, Oxford JS, McClain MT, Wilkinson T, Nicholson BP, Ginsburg GS, Devincenzo JP. Comparing influenza and RSV viral and disease dynamics in experimentally infected adults predicts clinical effectiveness of RSV antivirals. Antiviral Therapy. 18: 785-91. PMID 23714753 DOI: 10.3851/Imp2629  0.305
2013 Woods CW, McClain MT, Chen M, Zaas AK, Nicholson BP, Varkey J, Veldman T, Kingsmore SF, Huang Y, Lambkin-Williams R, Gilbert AG, Hero AO, Ramsburg E, Glickman S, Lucas JE, et al. A host transcriptional signature for presymptomatic detection of infection in humans exposed to influenza H1N1 or H3N2. Plos One. 8: e52198. PMID 23326326 DOI: 10.1371/Journal.Pone.0052198  0.307
2011 Moody MA, Zhang R, Walter EB, Woods CW, Ginsburg GS, McClain MT, Denny TN, Chen X, Munshaw S, Marshall DJ, Whitesides JF, Drinker MS, Amos JD, Gurley TC, Eudailey JA, et al. H3N2 influenza infection elicits more cross-reactive and less clonally expanded anti-hemagglutinin antibodies than influenza vaccination. Plos One. 6: e25797. PMID 22039424 DOI: 10.1371/Journal.Pone.0025797  0.352
2011 Huang Y, Zaas AK, Rao A, Dobigeon N, Woolf PJ, Veldman T, Øien NC, McClain MT, Varkey JB, Nicholson B, Carin L, Kingsmore S, Woods CW, Ginsburg GS, Hero AO. Temporal dynamics of host molecular responses differentiate symptomatic and asymptomatic influenza a infection. Plos Genetics. 7: e1002234. PMID 21901105 DOI: 10.1371/Journal.Pgen.1002234  0.335
2010 Heinlen LD, Ritterhouse LL, McClain MT, Keith MP, Neas BR, Harley JB, James JA. Ribosomal P autoantibodies are present before SLE onset and are directed against non-C-terminal peptides. Journal of Molecular Medicine (Berlin, Germany). 88: 719-27. PMID 20396862 DOI: 10.1007/S00109-010-0618-1  0.772
2010 Heinlen LD, McClain MT, Ritterhouse LL, Bruner BF, Edgerton CC, Keith MP, James JA, Harley JB. 60 kD Ro and nRNP A frequently initiate human lupus autoimmunity. Plos One. 5: e9599. PMID 20224770 DOI: 10.1371/Journal.Pone.0009599  0.745
2007 James JA, Kim-Howard XR, Bruner BF, Jonsson MK, McClain MT, Arbuckle MR, Walker C, Dennis GJ, Merrill JT, Harley JB. Hydroxychloroquine sulfate treatment is associated with later onset of systemic lupus erythematosus. Lupus. 16: 401-9. PMID 17664230 DOI: 10.1177/0961203307078579  0.78
2007 Heinlen LD, McClain MT, Merrill J, Akbarali YW, Edgerton CC, Harley JB, James JA. Clinical criteria for systemic lupus erythematosus precede diagnosis, and associated autoantibodies are present before clinical symptoms. Arthritis and Rheumatism. 56: 2344-51. PMID 17599763 DOI: 10.1002/Art.22665  0.787
2007 Heinlen L, McClain M, Prestigiacomo T, Bruner B, Binder S, Edgerton C, Rubertone M, James J, Harley J. Autoantibody Onset Prior to SLE Diagnosis Follows Predictable Patterns of Development Clinical Immunology. 123: S101. DOI: 10.1016/J.Clim.2007.03.467  0.761
2006 McClain MT, Poole BD, Bruner BF, Kaufman KM, Harley JB, James JA. An altered immune response to Epstein-Barr nuclear antigen 1 in pediatric systemic lupus erythematosus. Arthritis and Rheumatism. 54: 360-8. PMID 16385527 DOI: 10.1002/Art.21682  0.783
2006 Heinlen L, McClain M, Pachner A, Harley J, James J. Sa.16. Multiple Sclerosis Patients Exhibit a Unique Humoral Response to the Epstein-Barr Virus Nuclear Antigen-1 Clinical Immunology. 119: S110. DOI: 10.1016/J.Clim.2006.04.248  0.778
2006 Heinlen L, McClain M, Miner J, Scofield H, Harley J, James J. F.66. SLE Patient Anti-Ro 169 Antibodies Are Associated with Leucopenia and Bind the Surface of Neutrophils Clinical Immunology. 119: S74. DOI: 10.1016/J.Clim.2006.04.106  0.776
2005 Scofield RH, Kurien BT, Ganick S, McClain MT, Pye Q, James JA, Schneider RI, Broyles RH, Bachmann M, Hensley K. Modification of lupus-associated 60-kDa Ro protein with the lipid oxidation product 4-hydroxy-2-nonenal increases antigenicity and facilitates epitope spreading. Free Radical Biology & Medicine. 38: 719-28. PMID 15721982 DOI: 10.1016/J.Freeradbiomed.2004.11.001  0.578
2005 McClain MT, Heinlen LD, Dennis GJ, Roebuck J, Harley JB, James JA. Early events in lupus humoral autoimmunity suggest initiation through molecular mimicry. Nature Medicine. 11: 85-9. PMID 15619631 DOI: 10.1038/Nm1167  0.814
2004 McClain MT, Arbuckle MR, Heinlen LD, Dennis GJ, Roebuck J, Rubertone MV, Harley JB, James JA. The prevalence, onset, and clinical significance of antiphospholipid antibodies prior to diagnosis of systemic lupus erythematosus. Arthritis and Rheumatism. 50: 1226-32. PMID 15077305 DOI: 10.1002/Art.20120  0.803
2004 McClain MT, Lutz CS, Kaufman KM, Faig OZ, Gross TF, James JA. Structural availability influences the capacity of autoantigenic epitopes to induce a widespread lupus-like autoimmune response. Proceedings of the National Academy of Sciences of the United States of America. 101: 3551-6. PMID 14988508 DOI: 10.1073/Pnas.0306267101  0.531
2004 Kelleher P, James JA, McClain MT, Arbuckle MR, Harley JB. Autoantibodies before the Clinical Onset of Systemic Lupus Erythematosus [3] (multiple letters) New England Journal of Medicine. 350: 305. PMID 14724314 DOI: 10.1056/NEJM200401153500320  0.321
2004 Harley JB, Kelly JA, McClain MT, James JA. 9 THE GENES, ENVIRONMENT, AND HOST IMMUNE RESPONSES IN THE ETIOLOGY OF SYSTEMIC LUPUS ERYTHEMATOSUS. Journal of Investigative Medicine. 52: S258.4-S258. DOI: 10.1136/Jim-52-Suppl1-562  0.533
2003 Arbuckle MR, McClain MT, Rubertone MV, Scofield RH, Dennis GJ, James JA, Harley JB. Development of autoantibodies before the clinical onset of systemic lupus erythematosus. The New England Journal of Medicine. 349: 1526-33. PMID 14561795 DOI: 10.1056/Nejmoa021933  0.592
2003 Heinlen LD, McClain MT, Kim X, Quintero DR, James JA, Harley JB, Scofield RH. Anti-Ro and anti-nRNP response in unaffected family members of SLE patients. Lupus. 12: 335-7. PMID 12729062 DOI: 10.1191/0961203303lu377xx  0.767
2003 McClain MT, Rapp EC, Harley JB, James JA. Infectious mononucleosis patients temporarily recognize a unique, cross-reactive epitope of Epstein-Barr virus nuclear antigen-1. Journal of Medical Virology. 70: 253-7. PMID 12696112 DOI: 10.1002/Jmv.10385  0.614
2003 Arbuckle MR, James JA, Dennis GJ, Rubertone MV, McClain MT, Kim XR, Harley JB. Rapid clinical progression to diagnosis among African-American men with systemic lupus erythematosus. Lupus. 12: 99-106. PMID 12630753 DOI: 10.1191/0961203303Lu334Oa  0.553
2002 McClain MT, Scofield RH, Kurien BT, Gross TF, James JA. Selective small antigenic structures are capable of inducing widespread autoimmunity which closely mimics the humoral fine specificity of human SLE. Scandinavian Journal of Immunology. 56: 399-407. PMID 12234261 DOI: 10.1046/J.1365-3083.2002.01141.X  0.587
2002 Lutz CS, McClain MT, Harley JB, James JA. Anti-U1A monoclonal antibodies recognize unique epitope targets of U1A which are involved in the binding of U1 RNA. Journal of Molecular Recognition : Jmr. 15: 163-70. PMID 12203842 DOI: 10.1002/Jmr.569  0.525
2002 McClain MT, Ramsland PA, Kaufman KM, James JA. Anti-sm autoantibodies in systemic lupus target highly basic surface structures of complexed spliceosomal autoantigens. Journal of Immunology (Baltimore, Md. : 1950). 168: 2054-62. PMID 11823543 DOI: 10.4049/Jimmunol.168.4.2054  0.491
2001 McClain MT, Harley JB, James JA. The role of Epstein-Barr virus in systemic lupus erythematosus. Frontiers in Bioscience : a Journal and Virtual Library. 6: E137-47. PMID 11578968  0.538
2001 Kaufman KM, Kirby MY, McClain MT, Harley JB, James JA. Lupus autoantibodies recognize the product of an alternative open reading frame of SmB/B'. Biochemical and Biophysical Research Communications. 285: 1206-12. PMID 11478783 DOI: 10.1006/Bbrc.2001.5302  0.57
1999 James JA, McClain MT, Koelsch G, Williams DG, Harley JB. Side-chain specificities and molecular modelling of peptide determinants for two anti-Sm B/B' autoantibodies. Journal of Autoimmunity. 12: 43-9. PMID 10028021 DOI: 10.1006/Jaut.1998.0252  0.513
Low-probability matches (unlikely to be authored by this person)
2019 Ross MH, Henao R, Burke TW, McClain MT, Ginsburg GS, Woods CW, Tsalik EL, Tsalik EL. 1330. Evaluation of Multiple Host Response-Based Strategies to Classify Acute Respiratory Illness Open Forum Infectious Diseases. 6: S481-S481. DOI: 10.1093/Ofid/Ofz360.1194  0.295
2018 Tsalik EL, Henao R, Aydin M, Bullard C, Montgomery J, Nawrocki J, Deneris M, Gritzen C, Jones J, Crisp R, Mcclain MT, Burke T, Ginsburg GS, Hemmert A, Woods CW. 2012. FilmArray® Measurement of Host Response Signatures RapidLy Discriminates Viral, Bacterial, and Non-infectious Etiologies of Illness Open Forum Infectious Diseases. 5: S586-S586. DOI: 10.1093/Ofid/Ofy210.1668  0.282
2016 Sobel Leonard A, McClain MT, Smith GJ, Wentworth D, Halpin RA, Lin X, Ransier A, Stockwell TB, Das S, Gilbert AS, Lambkin-Williams R, Ginsburg GS, Woods CW, Koelle K. Deep Sequencing of Influenza A Virus from a Human Challenge Study Reveals a Selective Bottleneck and Only Limited Intrahost Genetic Diversification. Journal of Virology. PMID 27707932 DOI: 10.1128/Jvi.01657-16  0.282
2018 Lydon E, Bullard C, Aydin M, Better O, Mazur A, Mcclain MT, Ginsburg GS, Woods CW, Burke T, Henao R, Tsalik EL. 2014. TLDA Validation of a Host Response Signature to Discriminate Bacterial, Viral, and Non-infectious Causes of Illness Open Forum Infectious Diseases. 5: S587-S587. DOI: 10.1093/Ofid/Ofy210.1670  0.281
2018 Gayani Tillekeratne L, Suchindran S, Ko E, Petzold E, Bodinayake CK, Nagahawatte A, Devasiri V, Kurukulasooriya R, Reller ME, Nicholson BP, Burke T, Mcclain MT, Tsalik EL, Henao R, Ginsburg GS, et al. 2018. Host Gene Expression Classifiers Distinguish Bacterial and Viral Infections in Sri Lankan Patients with Acute Febrile Respiratory Illness Open Forum Infectious Diseases. 5: S588-S588. DOI: 10.1093/Ofid/Ofy210.1674  0.281
2017 Sobel Leonard A, McClain MT, Smith GJ, Wentworth DE, Halpin RA, Lin X, Ransier A, Stockwell TB, Das SR, Gilbert AS, Lambkin-Williams R, Ginsburg GS, Woods CW, Koelle K, Illingworth CJ. The effective rate of influenza reassortment is limited during human infection. Plos Pathogens. 13: e1006203. PMID 28170438 DOI: 10.1371/Journal.Ppat.1006203  0.281
2019 Bloom AS, Suchindran S, Steinbrink J, McClain MT. Utility of predictive tools for risk stratification of elderly individuals with all-cause acute respiratory infection. Infection. PMID 30929142 DOI: 10.1007/S15010-019-01299-1  0.279
2016 Berry SM, Petzold EA, Dull P, Thielman NM, Cunningham CK, Corey GR, McClain MT, Hoover DL, Russell J, Griffiss JM, Woods CW. A response adaptive randomization platform trial for efficient evaluation of Ebola virus treatments: A model for pandemic response. Clinical Trials (London, England). PMID 26768569 DOI: 10.1177/1740774515621721  0.277
2016 Yang WE, Suchindran S, Nicholson BP, McClain MT, Burke T, Ginsburg GS, Harro CD, Chakraborty S, Sack DA, Woods CW, Tsalik EL. Transcriptomic Analysis of the Host Response and Innate Resilience to Enterotoxigenic Escherichia coli Infection in Humans. The Journal of Infectious Diseases. PMID 26787651 DOI: 10.1093/Infdis/Jiv593  0.276
2020 Tillekeratne LG, Suchindran S, Ko ER, Petzold EA, Bodinayake CK, Nagahawatte A, Devasiri V, Kurukulasooriya R, Nicholson BP, McClain MT, Burke TW, Tsalik EL, Henao R, Ginsburg GS, Reller ME, et al. Previously Derived Host Gene Expression Classifiers Identify Bacterial and Viral Etiologies of Acute Febrile Respiratory Illness in a South Asian Population. Open Forum Infectious Diseases. 7: ofaa194. PMID 32617371 DOI: 10.1093/Ofid/Ofaa194  0.275
2016 McClain MT, Woods CW, Tsalik EL, Ginsburg GS, Nicholson BP, Burke T, Hudson L, Veldman T, Better O, Dobos S, Suchindran S, Nichols M, Valente A, Park L, Henao R. Host Transcriptomic Signatures for Early Diagnosis of Acute Respiratory Viral Infection in a University-Based Index-Cluster Cohort Open Forum Infectious Diseases. 3. DOI: 10.1093/Ofid/Ofw194.70  0.274
2015 Tsalik EL, McClain M, Zaas AK. Moving toward prime time: host signatures for diagnosis of respiratory infections. The Journal of Infectious Diseases. 212: 173-5. PMID 25637349 DOI: 10.1093/Infdis/Jiv032  0.27
2019 Tsalik EL, Khine A, Talebpour A, Samiei A, Parmar V, Burke TW, Mcclain MT, Ginsburg GS, Woods CW, Henao R, Alavie T. Rapid, Sample-to-Answer Host Gene Expression Test to Diagnose Viral Infection Open Forum Infectious Diseases. 6. DOI: 10.1093/Ofid/Ofz466  0.269
2018 Bloom A, Suchindran S, Mcclain MT. 725. Clinical Outcomes of Elderly Individuals Presenting with Acute Respiratory Infections Open Forum Infectious Diseases. 5: S260-S260. DOI: 10.1093/Ofid/Ofy210.732  0.263
2017 Muller J, Parizotto E, Antrobus R, Francis J, Bunce C, Stranks A, Nichols M, McClain M, Hill AVS, Ramasamy A, Gilbert SC. Development of an objective gene expression panel as an alternative to self-reported symptom scores in human influenza challenge trials. Journal of Translational Medicine. 15: 134. PMID 28595644 DOI: 10.1186/S12967-017-1235-3  0.259
2018 Poore GD, Ko ER, Valente A, Henao R, Sumner K, Hong C, Burke TW, Nichols M, McClain MT, Huang ES, Ginsburg GS, Woods CW, Tsalik EL. A miRNA Host Response Signature Accurately Discriminates Acute Respiratory Infection Etiologies. Frontiers in Microbiology. 9: 2957. PMID 30619110 DOI: 10.3389/Fmicb.2018.02957  0.258
2018 Bloom A, Suchindran S, Mazur A, Mcclain MT. 2019. Host Gene Expression Signatures for Diagnosis of Acute Respiratory Infections in the Elderly Open Forum Infectious Diseases. 5: S588-S588. DOI: 10.1093/Ofid/Ofy210.1675  0.254
2015 Yang WE, Suchindran S, Nicholson BP, McClain MT, Burke T, Ginsburg GS, Harro CD, Chakraborty S, Sack DA, Woods CW, Tsalik EL. Transcriptomic Analysis of the Host Response to Enterotoxigenic E. coli (ETEC) Infection in Humans Open Forum Infectious Diseases. 2. DOI: 10.1093/Ofid/Ofv133.594  0.253
2021 Garrido C, Hurst JH, Lorang CG, Aquino JN, Rodriguez J, Pfeiffer TS, Singh T, Semmes EC, Lugo DJ, Rotta AT, Turner NA, Burke TW, McClain MT, Petzold EA, Permar SR, et al. Asymptomatic or mild symptomatic SARS-CoV-2 infection elicits durable neutralizing antibody responses in children and adolescents. Jci Insight. PMID 34228642 DOI: 10.1172/jci.insight.150909  0.249
2021 Garrido C, Hurst JH, Lorang CG, Aquino JN, Rodriguez J, Pfeiffer TS, Singh T, Semmes EC, Lugo DJ, Rotta AT, Turner NA, Burke TW, McClain MT, Petzold EA, Permar SR, et al. Asymptomatic or mild symptomatic SARS-CoV-2 infection elicits durable neutralizing antibody responses in children and adolescents. Medrxiv : the Preprint Server For Health Sciences. PMID 33907760 DOI: 10.1101/2021.04.17.21255663  0.249
2021 McClain MT, Constantine FJ, Henao R, Liu Y, Tsalik EL, Burke TW, Steinbrink JM, Petzold E, Nicholson BP, Rolfe R, Kraft BD, Kelly MS, Saban DR, Yu C, Shen X, et al. Dysregulated transcriptional responses to SARS-CoV-2 in the periphery. Nature Communications. 12: 1079. PMID 33597532 DOI: 10.1038/s41467-021-21289-y  0.243
2016 Holcomb Z, Zaas A, Betancourt-Quiroz M, Perfect J, Mcclain MT. Identification of Host-Derived Biomarker Signatures in Cryptococcal Infection Open Forum Infectious Diseases. 3. DOI: 10.1093/Ofid/Ofw172.1274  0.242
2019 Woods CW, Sanchez AM, Swamy GK, McClain MT, Harrington L, Freeman D, Poore EA, Slifka DK, Poer DeRaad DE, Amanna IJ, Slifka MK, Cai S, Shahamatdar V, Wierzbicki MR, Amegashie C, et al. An observer blinded, randomized, placebo-controlled, phase I dose escalation trial to evaluate the safety and immunogenicity of an inactivated West Nile virus Vaccine, HydroVax-001, in healthy adults. Vaccine. PMID 30661836 DOI: 10.1016/J.Vaccine.2018.12.026  0.234
2019 Lydon EC, Bullard C, Aydin M, Better OM, Mazur A, Nicholson BP, Ko ER, McClain MT, Ginsburg GS, Woods CW, Burke TW, Henao R, Tsalik EL. A host gene expression approach for identifying triggers of asthma exacerbations. Plos One. 14: e0214871. PMID 30958855 DOI: 10.1371/Journal.Pone.0214871  0.233
2020 McClain MT, Constantine FJ, Henao R, Liu Y, Tsalik EL, Burke TW, Steinbrink JM, Petzold E, Nicholson BP, Rolfe R, Kraft BD, Kelly MS, Sempowski GD, Denny TN, Ginsburg GS, et al. Dysregulated transcriptional responses to SARS-CoV-2 in the periphery support novel diagnostic approaches. Medrxiv : the Preprint Server For Health Sciences. PMID 32743603 DOI: 10.1101/2020.07.20.20155507  0.232
2022 Giroux NS, Ding S, McClain MT, Burke TW, Petzold E, Chung HA, Rivera GO, Wang E, Xi R, Bose S, Rotstein T, Nicholson BP, Chen T, Henao R, Sempowski GD, et al. Differential chromatin accessibility in peripheral blood mononuclear cells underlies COVID-19 disease severity prior to seroconversion. Scientific Reports. 12: 11714. PMID 35810186 DOI: 10.1038/s41598-022-15668-8  0.226
2022 Giroux NS, Ding S, McClain MT, Burke TW, Petzold E, Chung HA, Rivera GO, Wang E, Xi R, Bose S, Rotstein T, Nicholson BP, Chen T, Henao R, Sempowski GD, et al. Differential chromatin accessibility in peripheral blood mononuclear cells underlies COVID-19 disease severity prior to seroconversion. Research Square. PMID 35411343 DOI: 10.21203/rs.3.rs-1479864/v1  0.226
2019 Madan A, Chen S, Yates P, Washburn ML, Roberts G, Peat AJ, Tao Y, Parry MF, Barnum O, McClain MT, Roy-Ghanta S. Efficacy and Safety of Danirixin (GSK1325756) Co-administered With Standard-of-Care Antiviral (Oseltamivir): A Phase 2b, Global, Randomized Study of Adults Hospitalized With Influenza. Open Forum Infectious Diseases. 6: ofz163. PMID 31041358 DOI: 10.1093/Ofid/Ofz163  0.221
2021 Tsalik EL, Fiorino C, Aqeel A, Liu Y, Henao R, Ko ER, Burke TW, Reller ME, Bodinayake CK, Nagahawatte A, Arachchi WK, Devasiri V, Kurukulasooriya R, McClain MT, Woods CW, et al. The Host Response to Viral Infections Reveals Common and Virus-Specific Signatures in the Peripheral Blood. Frontiers in Immunology. 12: 741837. PMID 34777354 DOI: 10.3389/fimmu.2021.741837  0.211
2023 Desai JV, Kumar D, Freiwald T, Chauss D, Johnson MD, Abers MS, Steinbrink JM, Perfect JR, Alexander B, Matzaraki V, Snarr BD, Zarakas MA, Oikonomou V, Silva LM, Shivarathri R, ... ... McClain MT, et al. C5a-licensed phagocytes drive sterilizing immunity during systemic fungal infection. Cell. PMID 37220746 DOI: 10.1016/j.cell.2023.04.031  0.211
2019 McClain MT, Sexton DJ. Surveillance for Spotted Fever Group Rickettsial Infections: Problems, Pitfalls and Potential Solutions. The Journal of Infectious Diseases. PMID 31267127 DOI: 10.1093/Infdis/Jiz317  0.208
2023 Hurst JH, Mohan AA, Dalapati T, George IA, Aquino JN, Lugo DJ, Pfeiffer TS, Rodriguez J, Rotta AT, Turner NA, Burke TW, McClain MT, Henao R, DeMarco CT, Louzao R, et al. Differential host responses within the upper respiratory tract and peripheral blood of children and adults with SARS-CoV-2 infection. Medrxiv : the Preprint Server For Health Sciences. PMID 37577568 DOI: 10.1101/2023.07.31.23293337  0.207
1998 McClain MT, Kaufman KM, Koelsch G, Harley JB, James JA. Identification and analysis of peptide determinants of murine monoclonal anti-Sm B/B' autoantibodies Faseb Journal. 12.  0.205
2018 Lydon E, Bullard C, Aydin M, Better O, Mazur A, Mcclain MT, Ginsburg GS, Woods CW, Burke T, Henao R, Tsalik EL. 2015. Host Gene Expression Identifies Infectious Triggers of Asthma Exacerbation Open Forum Infectious Diseases. 5: S587-S587. DOI: 10.1093/Ofid/Ofy210.1671  0.201
2023 McClain MT, Zhbannikov I, Satterwhite LL, Henao R, Giroux NS, Ding S, Burke TW, Tsalik EL, Nix C, Balcazar JP, Petzold EA, Shen X, Woods CW. Epigenetic and transcriptional responses in circulating leukocytes are associated with future decompensation during SARS-CoV-2 infection. Iscience. 27: 108288. PMID 38179063 DOI: 10.1016/j.isci.2023.108288  0.19
2020 Giroux NS, Ding S, McClain MT, Burke TW, Petzold E, Chung HA, Palomino GR, Wang E, Xi R, Bose S, Rotstein T, Nicholson BP, Chen T, Henao R, Sempowski GD, et al. Chromatin remodeling in peripheral blood cells reflects COVID-19 symptom severity. Biorxiv : the Preprint Server For Biology. PMID 33300002 DOI: 10.1101/2020.12.04.412155  0.181
2021 Jaffe IS, Jaehne AK, Quackenbush E, Ko ER, Rivers EP, McClain MT, Ginsburg GS, Woods CW, Tsalik EL. Comparing the Diagnostic Accuracy of Clinician Judgment to a Novel Host Response Diagnostic for Acute Respiratory Illness. Open Forum Infectious Diseases. 8: ofab564. PMID 34888402 DOI: 10.1093/ofid/ofab564  0.178
2021 Steinbrink JM, Myers RA, Hua K, Johnson MD, Seidelman JL, Tsalik EL, Henao R, Ginsburg GS, Woods CW, Alexander BD, McClain MT. The host transcriptional response to Candidemia is dominated by neutrophil activation and heme biosynthesis and supports novel diagnostic approaches. Genome Medicine. 13: 108. PMID 34225776 DOI: 10.1186/s13073-021-00924-9  0.178
2019 Colón-Emeric C, Pieper CF, Schmader KE, Sloane R, Bloom A, McClain M, Magaziner J, Huffman KM, Orwig D, Crabtree DM, Whitson HE. Two Approaches to Classifying and Quantifying Physical Resilience in Longitudinal Data. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 30993327 DOI: 10.1093/Gerona/Glz097  0.175
2023 Zhang Z, Sauerwald N, Cappuccio A, Ramos I, Nair VD, Nudelman G, Zaslavsky E, Ge Y, Gaitas A, Ren H, Brockman J, Geis J, Ramalingam N, King D, McClain MT, et al. Blood RNA alternative splicing events as diagnostic biomarkers for infectious disease. Cell Reports Methods. 3: 100395. PMID 36936082 DOI: 10.1016/j.crmeth.2023.100395  0.171
2020 McClain MT, Constantine FJ, Nicholson BP, Nichols M, Burke TW, Henao R, Jones DC, Hudson LL, Jaggers LB, Veldman T, Mazur A, Park LP, Suchindran S, Tsalik EL, Ginsburg GS, et al. A blood-based host gene expression assay for early detection of respiratory viral infection: an index-cluster prospective cohort study. The Lancet. Infectious Diseases. PMID 32979932 DOI: 10.1016/S1473-3099(20)30486-2  0.17
2023 Ko ER, Reller ME, Tillekeratne LG, Bodinayake CK, Miller C, Burke TW, Henao R, McClain MT, Suchindran S, Nicholson B, Blatt A, Petzold E, Tsalik EL, Nagahawatte A, Devasiri V, et al. Host-response transcriptional biomarkers accurately discriminate bacterial and viral infections of global relevance. Scientific Reports. 13: 22554. PMID 38110534 DOI: 10.1038/s41598-023-49734-6  0.166
2022 Fiorino C, Liu Y, Henao R, Ko ER, Burke TW, Ginsburg GS, McClain MT, Woods CW, Tsalik EL. Host Gene Expression to Predict Sepsis Progression. Critical Care Medicine. PMID 36178298 DOI: 10.1097/CCM.0000000000005675  0.165
2022 Holcomb ZE, Steinbrink JM, Zaas AK, Betancourt M, Tenor JL, Toffaletti DL, Alspaugh JA, Perfect JR, McClain MT. Transcriptional Profiles Elucidate Differential Host Responses to Infection with and . Journal of Fungi (Basel, Switzerland). 8. PMID 35628686 DOI: 10.3390/jof8050430  0.165
2021 Tsalik EL, Henao R, Montgomery JL, Nawrocki JW, Aydin M, Lydon EC, Ko ER, Petzold E, Nicholson BP, Cairns CB, Glickman SW, Quackenbush E, Kingsmore SF, Jaehne AK, Rivers EP, ... ... McClain MT, et al. Discriminating Bacterial and Viral Infection Using a Rapid Host Gene Expression Test. Critical Care Medicine. PMID 33938716 DOI: 10.1097/CCM.0000000000005085  0.159
2023 Steinbrink JM, Miller C, Myers RA, Sanoff S, Mazur A, Burke TW, Byrns J, Jackson AM, Luo X, McClain MT. Transcriptional responses define dysregulated immune activation in Hepatitis C (HCV)-naïve recipients of HCV-infected donor kidneys. Plos One. 18: e0280602. PMID 36701416 DOI: 10.1371/journal.pone.0280602  0.152
2022 McKittrick JM, Burke TW, Petzold E, Sempowski GD, Denny TN, Polage CR, Tsalik EL, McClain MT. SARS-CoV-2 reinfection across a spectrum of immunological states. Health Science Reports. 5: e554. PMID 35899182 DOI: 10.1002/hsr2.554  0.151
2019 Tsalik EL, Khine A, Talebpour A, Samiei A, Parmar V, Burke TW, Mcclain MT, Ginsburg GS, Woods CW, Henao R, Alavie T. Rapid, Sample-to-Answer Host Gene Expression Test to Diagnose Viral Infection. Open Forum Infectious Diseases. 6: ofz466. PMID 34150923 DOI: 10.1093/ofid/ofz466  0.15
2022 Cappuccio A, Chawla DG, Chen X, Rubenstein AB, Cheng WS, Mao W, Burke TW, Tsalik EL, Petzold E, Henao R, McClain MT, Woods CW, Chikina M, Troyanskaya OG, Sealfon SC, et al. Multi-objective optimization identifies a specific and interpretable COVID-19 host response signature. Cell Systems. 13: 989-1001.e8. PMID 36549275 DOI: 10.1016/j.cels.2022.11.008  0.149
2021 Ross M, Henao R, Burke TW, Ko ER, McClain MT, Ginsburg GS, Woods CW, Tsalik EL. A comparison of host response strategies to distinguish bacterial and viral infection. Plos One. 16: e0261385. PMID 34905580 DOI: 10.1371/journal.pone.0261385  0.142
2021 Grzesiak E, Bent B, McClain MT, Woods CW, Tsalik EL, Nicholson BP, Veldman T, Burke TW, Gardener Z, Bergstrom E, Turner RB, Chiu C, Doraiswamy PM, Hero A, Henao R, et al. Assessment of the Feasibility of Using Noninvasive Wearable Biometric Monitoring Sensors to Detect Influenza and the Common Cold Before Symptom Onset. Jama Network Open. 4: e2128534. PMID 34586364 DOI: 10.1001/jamanetworkopen.2021.28534  0.14
2023 Ortiz JR, Bernstein DI, Hoft DF, Woods CW, McClain MT, Frey SE, Brady RC, Bryant C, Wegel A, Frenck RW, Walter EB, Abate G, Williams SR, Atmar RL, Keitel WA, et al. A Multi-Center, Controlled Human Infection Study of Influenza A (H1N1)pdm09 in Healthy Adults. The Journal of Infectious Diseases. PMID 36702771 DOI: 10.1093/infdis/jiad021  0.128
2022 Schott BH, Wang L, Zhu X, Harding AT, Ko ER, Bourgeois JS, Washington EJ, Burke TW, Anderson J, Bergstrom E, Gardener Z, Paterson S, Brennan RG, Chiu C, McClain MT, et al. Single-cell genome-wide association reveals that a nonsynonymous variant in confers increased susceptibility to influenza virus. Cell Genomics. 2. PMID 36465279 DOI: 10.1016/j.xgen.2022.100207  0.126
2022 Ko ER, Henao R, Frankey K, Petzold EA, Isner PD, Jaehne AK, Allen N, Gardner-Gray J, Hurst G, Pflaum-Carlson J, Jayaprakash N, Rivers EP, Wang H, Ugalde I, Amanullah S, ... ... McClain MT, et al. Prospective Validation of a Rapid Host Gene Expression Test to Discriminate Bacterial From Viral Respiratory Infection. Jama Network Open. 5: e227299. PMID 35420659 DOI: 10.1001/jamanetworkopen.2022.7299  0.125
2020 Wang L, Balmat TJ, Antonia AL, Constantine FJ, Henao R, Burke TW, Ingham A, McClain MT, Tsalik EL, Ko ER, Ginsburg GS, DeLong MR, Shen X, Woods CW, Hauser ER, et al. An atlas connecting shared genetic architecture of human diseases and molecular phenotypes provides insight into COVID-19 susceptibility. Medrxiv : the Preprint Server For Health Sciences. PMID 33398303 DOI: 10.1101/2020.12.20.20248572  0.124
2021 Yu C, Littleton S, Giroux NS, Mathew R, Ding S, Kalnitsky J, Yang Y, Petzold E, Chung HA, Rivera GO, Rotstein T, Xi R, Ko ER, Tsalik EL, Sempowski GD, ... ... McClain MT, et al. Mucosal Associated Invariant T (MAIT) Cell Responses Differ by Sex in COVID-19. Med (New York, N.Y.). PMID 33870241 DOI: 10.1016/j.medj.2021.04.008  0.123
2016 Berry SM, Petzold EA, Dull P, Thielman NM, Cunningham CK, McClain MT, Hoover DL, Russell J, Griffiss JM, Woods CW. Response. Clinical Trials (London, England). PMID 27365016 DOI: 10.1177/1740774516654446  0.121
2023 Wang W, Hariharan M, Bartlett A, Barragan C, Castanon R, Rothenberg V, Song H, Nery J, Aldridge A, Altshul J, Kenworthy M, Ding W, Liu H, Tian W, Zhou J, ... ... McClain MT, et al. Human Immune Cell Epigenomic Signatures in Response to Infectious Diseases and Chemical Exposures. Biorxiv : the Preprint Server For Biology. PMID 37425926 DOI: 10.1101/2023.06.29.546792  0.119
2021 Mahle RE, Suchindran S, Henao R, Steinbrink JM, Burke TW, McClain MT, Ginsburg GS, Woods CW, Tsalik EL. Validation of a host gene expression test for bacterial/viral discrimination in immunocompromised hosts. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. PMID 33462581 DOI: 10.1093/cid/ciab043  0.118
2022 Temple DS, Hegarty-Craver M, Furberg RD, Preble EA, Bergstrom E, Gardener Z, Dayananda P, Taylor L, Lemm NM, Papargyris L, McClain MT, Nicholson BP, Bowie A, Miggs M, Petzold E, et al. Wearable sensor-based detection of influenza in presymptomatic and asymptomatic individuals. The Journal of Infectious Diseases. PMID 35759279 DOI: 10.1093/infdis/jiac262  0.115
2022 Tsalik EL, Rouphael NG, Sadikot RT, Rodriguez-Barradas MC, McClain MT, Wilkins DM, Woods CW, Swamy GK, Walter EB, El Sahly HM, Keitel WA, Mulligan MJ, Tuyishimire B, Serti E, Hamasaki T, et al. Efficacy and safety of azithromycin versus placebo to treat lower respiratory tract infections associated with low procalcitonin: a randomised, placebo-controlled, double-blind, non-inferiority trial. The Lancet. Infectious Diseases. PMID 36525985 DOI: 10.1016/S1473-3099(22)00735-6  0.111
2023 Bergin SP, Chemaly RF, Dadwal SS, Hill JA, Lee YJ, Haidar G, Luk A, Drelick A, Chin-Hong PV, Benamu E, Khawaja F, Nanayakkara D, Papanicolaou GA, Small CB, Fung M, ... ... McClain MT, et al. Plasma Microbial Cell-Free DNA Sequencing in Immunocompromised Patients with Pneumonia: A Prospective Observational Study. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. PMID 37815489 DOI: 10.1093/cid/ciad599  0.098
2022 Bodkin N, Ross M, McClain MT, Ko ER, Woods CW, Ginsburg GS, Henao R, Tsalik EL. Systematic comparison of published host gene expression signatures for bacterial/viral discrimination. Genome Medicine. 14: 18. PMID 35184750 DOI: 10.1186/s13073-022-01025-x  0.098
2021 Wang L, Balmat TJ, Antonia AL, Constantine FJ, Henao R, Burke TW, Ingham A, McClain MT, Tsalik EL, Ko ER, Ginsburg GS, DeLong MR, Shen X, Woods CW, Hauser ER, et al. An atlas connecting shared genetic architecture of human diseases and molecular phenotypes provides insight into COVID-19 susceptibility. Genome Medicine. 13: 83. PMID 34001247 DOI: 10.1186/s13073-021-00904-z  0.094
2023 Giroux NS, Ding S, McClain MT, Burke TW, Petzold E, Chung HA, Rivera GO, Wang E, Xi R, Bose S, Rotstein T, Nicholson BP, Chen T, Henao R, Sempowski GD, et al. Author Correction: Differential chromatin accessibility in peripheral blood mononuclear cells underlies COVID-19 disease severity prior to seroconversion. Scientific Reports. 13: 6462. PMID 37081034 DOI: 10.1038/s41598-023-33323-8  0.09
2024 Uthappa DM, McClain MT, Nicholson BP, Park LP, Zhbannikov I, Suchindran S, Jimenez M, Constantine FJ, Nichols M, Jones DC, Hudson LL, Jaggers LB, Veldman T, Burke TW, Tsalik EL, et al. Implementation of a Prospective Index-Cluster Sampling Strategy for the Detection of Presymptomatic Viral Respiratory Infection in Undergraduate Students. Open Forum Infectious Diseases. 11: ofae081. PMID 38440301 DOI: 10.1093/ofid/ofae081  0.083
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