Malcolm J. Low, M.D., Ph.D - Related publications

Oregon Health and Science University, Portland, OR 
 Molecular & Integrative Physiology and Metabolism, Endocrinology & Diabetes University of Michigan, Ann Arbor, Ann Arbor, MI 
obesity, diabetes, hypothalamus
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50 most relevant papers in past 60 days:
Year Citation  Score
2020 Ferguson D, Hutson I, Tycksen E, Pietka TA, Bauerle K, Harris CA. Role of Mineralocorticoid Receptor in Adipogenesis and Obesity in Male Mice. Endocrinology. 161. PMID 32036385 DOI: 10.1210/endocr/bqz010   
2020 Ji M, Xu K, ZHang D, Chen T, Shen L, Wu W, Zhang J. Adipose tissue-specific expression of pig apoR protects mice from diet-induced obesity. Journal of Agricultural and Food Chemistry. PMID 31927923 DOI: 10.1021/acs.jafc.9b06995   
2020 Yang X, Zhao Y, Sun Q, Yang Y, Gao Y, Ge W, Liu J, Xu X, Zhang J. Adenosine accumulation causes metabolic disorders in testes and associates with lower testosterone level in obese mice. Molecular Reproduction and Development. PMID 32026564 DOI: 10.1002/mrd.23321   
2020 Pushpavathi Selvakumar G, Ejaz Ahmed M, Thangavel R, Kempuraj D, Dubova I, Raikwar SP, Zaheer S, Iyer SS, Zaheer A. A role for glia maturation factor dependent activation of mast cells and microglia in MPTP induced dopamine loss and behavioural deficits in mice. Brain, Behavior, and Immunity. PMID 31982500 DOI: 10.1016/j.bbi.2020.01.013   
2020 Rosenstand K, Andersen K, Terp R, Gennemark P, Ellman DG, Reznichenko A, Lambertsen KL, Vanhoutte PM, Hansen PBL, Svenningsen P. Deficiency of T-type voltage-gated calcium channels results in attenuated weight gain and improved endothelium-dependent dilatation of resistance vessels induced by a high-fat diet in mice. Journal of Physiology and Biochemistry. PMID 32016773 DOI: 10.1007/s13105-020-00728-2   
2020 Emmer BT, Lascuna PJ, Tang VT, Kotnik EN, Saunders TL, Khoriaty R, Ginsburg D. Murine Surf4 is essential for early embryonic development. Plos One. 15: e0227450. PMID 31978056 DOI: 10.1371/journal.pone.0227450   
2020 Yao Y. Ginsenosides reduce body weight and ameliorate hepatic steatosis in high fat diet‑induced obese mice via endoplasmic reticulum stress and p‑STAT3/STAT3 signaling. Molecular Medicine Reports. PMID 32016448 DOI: 10.3892/mmr.2020.10935   
2020 Tsuru S, Ito Y, Matsuda H, Hosono K, Inoue T, Nakamoto S, Kurashige C, Mishima T, Tsujikawa K, Okamoto H, Majima M. RAMP1 signaling in immune cells regulates inflammation-associated lymphangiogenesis. Laboratory Investigation; a Journal of Technical Methods and Pathology. PMID 31911634 DOI: 10.1038/s41374-019-0364-0   
2020 Kokubun H, Jin H, Komita M, Aoe T. Conflicting Actions of Inhalational Anesthetics, Neurotoxicity and Neuroprotection, Mediated by the Unfolded Protein Response. International Journal of Molecular Sciences. 21. PMID 31936788 DOI: 10.3390/ijms21020450   
2020 Priyadarshini M, Cole C, Oroskar G, Ludvik AE, Wicksteed B, He C, Layden BT. Free Fatty Acid Receptor 3 Differentially Contributes to Beta Cell Compensation Under High Fat Diet and Streptozotocin Stress. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. PMID 32073900 DOI: 10.1152/ajpregu.00128.2019   
2020 Wooton-Kee CR, Robertson M, Zhou Y, Dong B, Sun Z, Kim KH, Liu H, Xu Y, Putluri N, Saha P, Coarfa C, Moore DD, Nuotio-Antar AM. Metabolic dysregulation in the Wilson's disease mouse model. Proceedings of the National Academy of Sciences of the United States of America. PMID 31924743 DOI: 10.1073/pnas.1914267117   
2020 Shindo R, Katagiri T, Komazawa-Sakon S, Ohmuraya M, Takeda W, Nakagawa Y, Nakagata N, Sakuma T, Yamamoto T, Nishiyama C, Nishina T, Yamazaki S, Kameda H, Nakano H. Regenerating islet-derived protein (Reg)3β plays a crucial role in attenuation of ileitis and colitis in mice. Biochemistry and Biophysics Reports. 21: 100738. PMID 32072024 DOI: 10.1016/j.bbrep.2020.100738   
2020 Kwon E, Yoo T, Joung HY, Jo YH. Hydrocarboxylic acid receptor 1 in BAT regulates glucose uptake in mice fed a high-fat diet. Plos One. 15: e0228320. PMID 31999787 DOI: 10.1371/journal.pone.0228320   
2020 Shieh KR, Yang SC. Formosan wood mice () exhibit more exploratory behaviors and central dopaminergic activities than C57BL/6 mice in the open field test. The Chinese Journal of Physiology. 63: 27-34. PMID 32056984 DOI: 10.4103/CJP.CJP_47_19   
2020 Li ZG, Shui SF, Han XW, Yan L. NLRP10 ablation protects against ischemia/reperfusion-associated brain injury by suppression of neuroinflammation. Experimental Cell Research. 111912. PMID 32084391 DOI: 10.1016/j.yexcr.2020.111912   
2020 Jiménez-Altayó F, Ortiz-Romero P, Puertas-Umbert L, Dantas AP, Pérez B, Vila E, D'Ocon P, Campuzano V. Stenosis coexists with compromised α1-adrenergic contractions in the ascending aorta of a mouse model of Williams-Beuren syndrome. Scientific Reports. 10: 889. PMID 31965005 DOI: 10.1038/s41598-020-57803-3   
2020 Schirmer B, Lindemann L, Bittkau KS, Isaev R, Bösche D, Juchem M, Seifert R, Neumann D. MOUSE COLONIC EPITHELIAL CELLS FUNCTIONALLY EXPRESS THE HISTAMINE H RECEPTOR. The Journal of Pharmacology and Experimental Therapeutics. PMID 32029576 DOI: 10.1124/jpet.119.264408   
2020 Jirkof P, Bratcher N, Medina L, Strasburg D, Ebert P, Gaskill BN. The effect of group size, age and handling frequency on inter-male aggression in CD 1 mice. Scientific Reports. 10: 2253. PMID 32042065 DOI: 10.1038/s41598-020-59012-4   
2020 Rubinow KB, den Hartigh LJ, Goodspeed L, Wang S, Oz OK. Aromatase deficiency in hematopoietic cells improves glucose tolerance in male mice through skeletal muscle-specific effects. Plos One. 15: e0227830. PMID 31971970 DOI: 10.1371/journal.pone.0227830   
2020 Beebe NL, Sowick CS, Kristaponyte I, Galazyuk AV, Vetter DE, Cox BC, Schofield BR. Generation of a ChAT mouse line without the early onset hearing loss typical of the C57BL/6J strain. Hearing Research. 388: 107896. PMID 31982642 DOI: 10.1016/j.heares.2020.107896   
2020 Wu R, Yu W, Fu L, Li F, Jing J, Cui X, Wang S, Cao Q, Xue B, Shi H. The postnatal leptin surge is critical for the transient induction of the developmental beige adipocytes in mice. American Journal of Physiology. Endocrinology and Metabolism. PMID 31961706 DOI: 10.1152/ajpendo.00292.2019   
2020 Gu SX, Sonkar VK, Katare PB, Kumar R, Kruger WD, Arning E, Bottiglieri T, Lentz SR, Dayal S. Memantine Protects From Exacerbation of Ischemic Stroke and Blood Brain Barrier Disruption in Mild But Not Severe Hyperhomocysteinemia. Journal of the American Heart Association. 9: e013368. PMID 32067580 DOI: 10.1161/JAHA.119.013368   
2020 Oliveira CF, Lara NL, Lacerda SM, Resende RR, França LR, Avelar GF. Foxn1 and Prkdc genes are important for testis function: evidence from nude and scid adult mice. Cell and Tissue Research. PMID 31950264 DOI: 10.1007/s00441-019-03165-w   
2020 Ávila-Pérez G, Nogales A, Park JG, Vasquez DM, Dean DA, Barravecchia M, Perez DR, Almazán F, Martínez-Sobrido L. In vivo rescue of recombinant Zika virus from an infectious cDNA clone and its implications in vaccine development. Scientific Reports. 10: 512. PMID 31949262 DOI: 10.1038/s41598-020-57545-2   
2020 Miles KN, Skelton MR. Male mice placed on a ketogenic diet from postnatal day (P) 21 through adulthood have reduced growth, are hypoactive, show increased freezing in a conditioned fear paradigm, and have spatial learning deficits. Brain Research. 146697. PMID 32014530 DOI: 10.1016/j.brainres.2020.146697   
2020 Yuan J, Li Q, Ommati MM, Niu R, Wang J. Detrimental Effects of Sodium Fluoride on the Expression of Insulin Receptor in the Olfactory Bulb and Hippocampus of Male Mice. Biological Trace Element Research. PMID 32016826 DOI: 10.1007/s12011-020-02053-7   
2020 Guan L, Yu WS, Shrestha S, Or YZ, Lufkin T, Chan YS, Cllin V, Lim LW. TTC9A deficiency induces estradiol-mediated changes in hippocampus and amygdala neuroplasticity-related gene expressions in female mice. Brain Research Bulletin. PMID 32057953 DOI: 10.1016/j.brainresbull.2020.02.004   
2020 Zhang SL, Li ZY, Wang DS, Xu TY, Fan MB, Cheng MH, Miao CY. Aggravated ulcerative colitis caused by intestinal Metrnl deficiency is associated with reduced autophagy in epithelial cells. Acta Pharmacologica Sinica. PMID 31949292 DOI: 10.1038/s41401-019-0343-4   
2020 Lindhorst A, Bechmann I, Gericke M. Unspecific DNA recombination in AdipoqCre-ER - mediated knockout approaches in transgenic mice is sex-, age- and genotype-dependent. Adipocyte. 9: 1-6. PMID 31842670 DOI: 10.1080/21623945.2019.1701394   
2020 Yousefzadeh MJ, Zhao J, Bukata C, Wade EA, McGowan SJ, Angelini LA, Bank MP, Gurkar AU, McGuckian CA, Calubag MF, Kato JI, Burd CE, Robbins PD, Niedernhofer LJ. Tissue specificity of senescent cell accumulation during physiologic and accelerated aging of mice. Aging Cell. e13094. PMID 31981461 DOI: 10.1111/acel.13094   
2020 Haugen ØP, Vallenari EM, Belhaj I, Småstuen MC, Storm-Mathisen J, Bergersen LH, Åmellem I. Blood lactate dynamics in awake and anaesthetized mice after intraperitoneal and subcutaneous injections of lactate-sex matters. Peerj. 8: e8328. PMID 31934509 DOI: 10.7717/peerj.8328   
2020 Kim S, Lee Y, Kim Y, Seo Y, Lee H, Ha J, Lee J, Choi Y, Oh H, Yoon Y. Prevents Fatty Liver, Decreases Serum Triglycerides, and Maintains Gut Homeostasis. Applied and Environmental Microbiology. PMID 31953338 DOI: 10.1128/AEM.03004-19   
2020 Yamamoto H, Hattori M, Chamulitrat W, Ohno Y, Kihara A. Skin permeability barrier formation by the ichthyosis-causative gene through formation of the barrier lipid ω--acylceramide. Proceedings of the National Academy of Sciences of the United States of America. PMID 31974308 DOI: 10.1073/pnas.1917525117   
2020 Hoekstra M, van der Sluis RJ, Hildebrand RB, Lammers B, Zhao Y, Praticò D, van Berkel TJC, Rensen PCN, Kooijman S, Jauhiainen M, van Eck M. Disruption of PLTP (Phospholipid Transfer Protein)-Mediated HDL (High-Density Lipoprotein) Maturation Reduces SR-BI (Scavenger Receptor BI) Deficiency-Driven Atherosclerosis Susceptibility Despite Unexpected Metabolic Complications. Arteriosclerosis, Thrombosis, and Vascular Biology. ATVBAHA119313862. PMID 31941380 DOI: 10.1161/ATVBAHA.119.313862   
2020 Kohno D, Furusawa K, Kitamura T. Anagliptin suppresses diet-induced obesity through enhancing leptin sensitivity and ameliorating hyperphagia in high-fat high-sucrose diet fed mice. Endocrine Journal. PMID 32009061 DOI: 10.1507/endocrj.EJ19-0389   
2020 Endicott SJ, Boynton DN, Beckmann LJ, Miller RA. Long-Lived Mice with Reduced Growth Hormone Signaling Have a Constitutive Upregulation of Hepatic Chaperone-Mediated Autophagy. Autophagy. PMID 32013718 DOI: 10.1080/15548627.2020.1725378   
2020 Zidon TM, Padilla J, Fritsche KL, Welly RJ, McCabe LT, Stricklin OE, Frank AP, Park YM, Clegg DJ, Lubahn D, Kanaley J, Vieira-Potter V. Effects of ERβ and ERα on OVX-induced changes in adiposity and insulin resistance. The Journal of Endocrinology. PMID 32053493 DOI: 10.1530/JOE-19-0321   
2020 Ito I, Loucas BD, Suzuki S, Kobayashi M, Suzuki F. Glycyrrhizin Protects γ-Irradiated Mice from Gut Bacteria-Associated Infectious Complications by Improving -Associated RNA Reduction in Macrophages of the Bacterial Translocation Site. Journal of Immunology (Baltimore, Md. : 1950). PMID 31941655 DOI: 10.4049/jimmunol.1900949   
2020 Kim YY, Chao JR, Kim C, Kim B, Thi-Thanh Nguyen P, Jung H, Chang J, Lee JH, Suh JG. Hearing loss through apoptosis of the spiral ganglion neurons in apolipoprotein E knockout mice fed with a western diet. Biochemical and Biophysical Research Communications. PMID 31948760 DOI: 10.1016/j.bbrc.2019.12.100   
2020 Akahoshi N, Minakawa T, Miyashita M, Sugiyama U, Saito C, Takemoto R, Honda A, Kamichatani W, Kamata S, Anan Y, Ishii I. Increased Urinary 3-Mercaptolactate Excretion and Enhanced Passive Systemic Anaphylaxis in Mice Lacking Mercaptopyruvate Sulfurtransferase, a Model of Mercaptolactate-Cysteine Disulfiduria. International Journal of Molecular Sciences. 21. PMID 32012740 DOI: 10.3390/ijms21030818   
2020 Kang D, Kim HR, Kim KK, Kim DH, Jeong B, Jin S, Park JW, Seong JY, Lee BJ. Brain-specific chemokine FAM19A5 induces hypothalamic inflammation. Biochemical and Biophysical Research Communications. PMID 31954515 DOI: 10.1016/j.bbrc.2019.12.119   
2020 Shahini N, Schjalm C, Nilsson PH, Holt MF, Øgaard JDS, Lien E, Ahmed MS, Attramadal H, Aukrust P, Yndestad A, Mollnes TE, Louwe MC. Complement component C3 and the TLR co-receptor CD14 are not involved in angiotensin II induced cardiac remodelling. Biochemical and Biophysical Research Communications. PMID 31955888 DOI: 10.1016/j.bbrc.2020.01.018   
2020 Sharma S, Plotkin M. Id1 expression in kidney endothelial cells protects against diabetes-induced microvascular injury. Febs Open Bio. PMID 31957231 DOI: 10.1002/2211-5463.12793   
2020 He M, Zhao WB, Nguyen MN, Kiriazis H, Li YQ, Hu H, Du XJ. Association Between Heart Rate Variability Indices and Features of Spontaneous Ventricular Tachyarrhythmias in Mice. Clinical and Experimental Pharmacology & Physiology. PMID 32027390 DOI: 10.1111/1440-1681.13275   
2020 Lackey AI, Chen T, Zhou YX, Bottasso Arias NM, Doran JM, Zacharisen SM, Gajda AM, Córsico B, Joseph LB, Storch J. Mechanisms underlying reduced weight gain in Intestinal Fatty Acid-Binding Protein (IFABP) null mice. American Journal of Physiology. Gastrointestinal and Liver Physiology. PMID 31905021 DOI: 10.1152/ajpgi.00120.2019   
2020 Jiang W, Li W, Hu X, Hu R, Li B, Lan L. CTRP1 prevents sepsis-induced cardiomyopathy via Sirt1-dependent pathways. Free Radical Biology & Medicine. PMID 31991227 DOI: 10.1016/j.freeradbiomed.2020.01.178   
2020 Wang R, Deng Y, Deng Q, Sun D, Fang Z, Sun L, Wang Y, Gooneratne R. Infection in Mice Reduces Protective Gut Microbiota, Augmenting Disease Pathways. Frontiers in Microbiology. 11: 73. PMID 32082289 DOI: 10.3389/fmicb.2020.00073   
2020 Miyata M, Funaki A, Fukuhara C, Sumiya Y, Sugiura Y. Taurine attenuates hepatic steatosis in a genetic model of fatty liver disease. The Journal of Toxicological Sciences. 45: 87-94. PMID 32062620 DOI: 10.2131/jts.45.87   
2020 Sharma G, Hu C, Staquicini DI, Brigman JL, Liu M, Mauvais-Jarvis F, Pasqualini R, Arap W, Arterburn JB, Hathaway HJ, Prossnitz ER. Preclinical efficacy of the GPER-selective agonist G-1 in mouse models of obesity and diabetes. Science Translational Medicine. 12. PMID 31996464 DOI: 10.1126/scitranslmed.aau5956   
2020 Li Y, Wang S, Sun Y, Xu W, Zheng H, Wang Y, Tang Y, Gao X, Song C, Long Y, Liu J, Liu L, Mei Q. Apple polysaccharide protects ICR mice against colitis associated colorectal cancer through the regulation of microbial dysbiosis. Carbohydrate Polymers. 230: 115726. PMID 31887919 DOI: 10.1016/j.carbpol.2019.115726