Roger Guillemin - Publications

Affiliations: 
1953-1970 Physiology Baylor College of Medicine, Houston, TX 
 1960-1963 College de France, Paris, Île-de-France, France 
 1970-1989 Neuroendocrinology Salk Institute for Biological Studies, La Jolla, CA, United States 
Area:
Neuroendocrinology
Website:
http://www.nobelprize.org/nobel_prizes/medicine/laureates/1977/guillemin-bio.html

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Year Citation  Score
2014 Guillemin R. Foreword to the proceedings of the "Selye symposium - 2013", held at the hungarian academy of sciences, Budapest, Hungary, may 8, 2013 Ideggyogyaszati Szemle. 67: 77-78.  1
2013 Guillemin R. A conversation with Roger Guillemin. Interview by Greg Lemke. Annual Review of Physiology. 75: 1-22. PMID 23398151 DOI: 10.1146/annurev-physiol-082712-104641  1
2013 Bomme C, Guillemin R, Sheinerman S, Marin T, Journel L, Marchenko T, Kushawaha RK, Trcera N, Piancastelli MN, Simon M. Post-collision interaction manifestation in molecular systems probed by photoelectron-molecular ion coincidences Journal of Physics B: Atomic, Molecular and Optical Physics. 46. DOI: 10.1088/0953-4075/46/21/215101  0.01
2012 Guillemin R, Stolte WC, Journel L, Carniato S, Piancastelli MN, Lindle DW, Simon M. Angular and dynamical properties in resonant inelastic x-ray scattering: Case study of chlorine-containing molecules Physical Review a - Atomic, Molecular, and Optical Physics. 86. DOI: 10.1103/PhysRevA.86.013407  0.01
2011 Guillemin R. Neuroendocrinology: a short historical review. Annals of the New York Academy of Sciences. 1220: 1-5. PMID 21388398 DOI: 10.1111/j.1749-6632.2010.05936.x  1
2010 Guillemin R. "en guise d'introduction ...". Progress in Brain Research. 181: vii-viii. PMID 20478428 DOI: 10.1016/S0079-6123(08)81019-9  1
2010 Guillemin R. Similarities and contrasts in the creative processes of the sciences and the arts Leonardo. 43: 59-62. DOI: 10.1162/leon.2010.43.1.59  1
2010 Guillemin R, Stolte WC, Piancastelli MN, Lindle DW. Jahn-teller coupling and fragmentation after core-shell excitation in CF4 investigated by partial-ion-yield spectroscopy Physical Review a - Atomic, Molecular, and Optical Physics. 82. DOI: 10.1103/PhysRevA.82.043427  0.01
2009 Guillemin R, Stolte WC, Lindle DW. Fragmentation of formic acid following photoexcitation around the carbon K edge Journal of Physics B: Atomic, Molecular and Optical Physics. 42. DOI: 10.1088/0953-4075/42/12/125101  0.01
2008 Guillemin R, Perrin MH. Neuroendocrinology: past, present and future. Annales D'Endocrinologie. 69: 160. PMID 18407243 DOI: 10.1016/j.ando.2008.02.018  1
2008 Guillemin R. Somatostatin: the beginnings, 1972. Molecular and Cellular Endocrinology. 286: 3-4. PMID 18395969 DOI: 10.1016/j.mce.2008.02.025  1
2006 Guillemin R. Acromegaly, day one and now, 120 years later. Neuroendocrinology. 83: 136-8. PMID 17047375 DOI: 10.1159/000095520  1
2006 Guillemin R. Basic research and the practice of medicine. Annales De Cardiologie Et D'AngéIologie. 55: 63. PMID 16708986 DOI: 10.1016/j.ancard.2006.02.006  1
2005 Guillemin R. Hypothalamic hormones a.k.a. hypothalamic releasing factors. The Journal of Endocrinology. 184: 11-28. PMID 15642779 DOI: 10.1677/joe.1.05883  1
2004 Guillemin R. Neuroendocrine basis of human disease. Annals of the New York Academy of Sciences. 1038: 131-7. PMID 15838107 DOI: 10.1196/annals.1315.021  1
2003 Orians G, Briand F, Diamond J, Colborn T, Gomez E, Guillemin R, Klug SA, Konishi M, Lubchenco J, Mee L, Norse E, Di Sciara GN, Payne R, Safina C, Suzuki D, et al. "Scientists versus Whaling": Whose errors of judgment? [2] Bioscience. 53: 200-203.  1
1998 Guillemin R. Review on somatostatin and somatostatin analogs. State of the art in digestive endocrinology | Mises au point sur la somatostatine et ses analogues actualites en endocrinologie digestive. Histoire de la decouverte de la somatostatine Annales D'Endocrinologie. 59: 49.  1
1998 Guillemin R. History of the discovery of somatostatin | Histoire de la decouverte de la somatostatine Annales D'Endocrinologie. 59: 4-5.  1
1993 Guillemin R. Somatostatin: the early days. Digestion. 54: 3-6. PMID 8103012 DOI: 10.1159/000201066  1
1992 Guillemin R. Somatostatin: the early days. Metabolism: Clinical and Experimental. 41: 2-4. PMID 1355587 DOI: 10.1016/0026-0495(92)90022-3  1
1990 Guillemin R. Some thoughts on the occasion of the fifth anniversary of medecine/sciences | QUELQUES REFLEXIONS A L'OCCASION DU 5e ANNIVERSAIRE DE MEDECINE/SCIENCES Medecine/Sciences. 6: 214-215.  1
1988 Shimasaki S, Koga M, Esch F, Cooksey K, Mercado M, Koba A, Ueno N, Ying SY, Ling N, Guillemin R. Primary structure of the human follistatin precursor and its genomic organization. Proceedings of the National Academy of Sciences of the United States of America. 85: 4218-22. PMID 3380788  1
1988 Ying SY, Ling N, Guillemin R. Inhibins and activins. Structures and radioimmunoassays. Annals of the New York Academy of Sciences. 541: 143-52. PMID 3195902  1
1988 Ling N, Ueno N, Ying SY, Esch F, Shimasaki S, Hotta M, Cuevas P, Guillemin R. Inhibins and activins. Vitamins and Hormones. 44: 1-46. PMID 3070928  1
1988 Cheifetz S, Ling N, Guillemin R, Massagué J. A surface component on GH3 pituitary cells that recognizes transforming growth factor-beta, activin, and inhibin. The Journal of Biological Chemistry. 263: 17225-8. PMID 2903159  1
1988 Baird A, Schubert D, Ling N, Guillemin R. Receptor- and heparin-binding domains of basic fibroblast growth factor. Proceedings of the National Academy of Sciences of the United States of America. 85: 2324-8. PMID 2832850 DOI: 10.1073/pnas.85.7.2324  1
1988 Leppäluoto J, Zeytin F, Ueno N, Ying SY, Ling N, Guillemin R. Myelin basic protein present in the acid extracts of rat hypothalami releases insulin and glucagon from isolated rat pancreatic islets. Acta Physiologica Scandinavica. 134: 253-61. PMID 2465673 DOI: 10.1111/j.1748-1716.1988.tb08486.x  1
1987 Ueno N, Baird A, Esch F, Ling N, Guillemin R. Isolation and partial characterization of basic fibroblast growth factor from bovine testis. Molecular and Cellular Endocrinology. 49: 189-94. PMID 3556754 DOI: 10.1016/0303-7207(87)90212-7  1
1987 Cuevas P, Ying SY, Ling N, Ueno N, Esch F, Guillemin R, Healy D, Ta S. Immunohistochemical detection of inhibin in the gonad. Biochemical and Biophysical Research Communications. 142: 23-30. PMID 3545204 DOI: 10.1016/0006-291X(87)90446-3  1
1987 Esch FS, Shimasaki S, Mercado M, Cooksey K, Ling N, Ying S, Ueno N, Guillemin R. Structural characterization of follistatin: a novel follicle-stimulating hormone release-inhibiting polypeptide from the gonad. Molecular Endocrinology (Baltimore, Md.). 1: 849-55. PMID 3153465 DOI: 10.1210/mend-1-11-849  1
1987 Ying SY, Becker A, Swanson G, Tan P, Ling N, Esch F, Ueno N, Shimasaki S, Guillemin R. Follistatin specifically inhibits pituitary follicle stimulating hormone release in vitro. Biochemical and Biophysical Research Communications. 149: 133-9. PMID 3120723 DOI: 10.1016/0006-291X(87)91614-7  1
1987 Ueno N, Ling N, Ying SY, Esch F, Shimasaki S, Guillemin R. Isolation and partial characterization of follistatin: a single-chain Mr 35,000 monomeric protein that inhibits the release of follicle-stimulating hormone. Proceedings of the National Academy of Sciences of the United States of America. 84: 8282-6. PMID 3120188  1
1987 Ying SY, Czvik J, Becker A, Ling N, Ueno N, Guillemin R. Secretion of follicle-stimulating hormone and production of inhibin are reciprocally related. Proceedings of the National Academy of Sciences of the United States of America. 84: 4631-5. PMID 3110772 DOI: 10.1073/pnas.84.13.4631  1
1987 Ling N, Ying SY, Ueno N, Shimasaki S, Esch F, Hotta M, Guillemin R. Pituitary FSH is released by a heterodimer of the β-subunits from the two forms of inhibin Obstetrical and Gynecological Survey. 42: 109-111.  1
1986 Ueno N, Baird A, Esch F, Shimasaki S, Ling N, Guillemin R. Purification and partial characterization of a mitogenic factor from bovine liver: structural homology with basic fibroblast growth factor. Regulatory Peptides. 16: 135-45. PMID 3809608 DOI: 10.1016/0167-0115(86)90057-1  1
1986 Ueno N, Baird A, Esch F, Ling N, Guillemin R. Isolation of an amino terminal extended form of basic fibroblast growth factor. Biochemical and Biophysical Research Communications. 138: 580-8. PMID 3741423 DOI: 10.1016/S0006-291X(86)80536-8  1
1986 Baird A, Esch F, Mormède P, Ueno N, Ling N, Böhlen P, Ying SY, Wehrenberg WB, Guillemin R. Molecular characterization of fibroblast growth factor: distribution and biological activities in various tissues. Recent Progress in Hormone Research. 42: 143-205. PMID 3526451  1
1986 Walicke P, Cowan WM, Ueno N, Baird A, Guillemin R. Fibroblast growth factor promotes survival of dissociated hippocampal neurons and enhances neurite extension. Proceedings of the National Academy of Sciences of the United States of America. 83: 3012-6. PMID 3458259  1
1986 Sassolas G, Guillemin R. [Current status of somatocrinin, or GRF, a hypothalamic growth hormone-secreting factor]. Annales D'Endocrinologie. 47: 332-41. PMID 3103519  1
1986 Ling N, Ying SY, Ueno N, Shimasaki S, Esch F, Hotta M, Guillemin R. A homodimer of the beta-subunits of inhibin A stimulates the secretion of pituitary follicle stimulating hormone. Biochemical and Biophysical Research Communications. 138: 1129-37. PMID 3092817 DOI: 10.1016/S0006-291X(86)80400-4  1
1986 Ying SY, Becker A, Ling N, Ueno N, Guillemin R. Inhibin and beta type transforming growth factor (TGF beta) have opposite modulating effects on the follicle stimulating hormone (FSH)-induced aromatase activity of cultured rat granulosa cells. Biochemical and Biophysical Research Communications. 136: 969-75. PMID 3087350 DOI: 10.1016/0006-291X(86)90427-4  1
1986 Ling N, Ying SY, Ueno N, Shimasaki S, Esch F, Hotta M, Guillemin R. Pituitary FSH is released by a heterodimer of the beta-subunits from the two forms of inhibin. Nature. 321: 779-82. PMID 3086749 DOI: 10.1038/321779a0  1
1986 Ying SY, Becker A, Baird A, Ling N, Ueno N, Esch F, Guillemin R. Type beta transforming growth factor (TGF-beta) is a potent stimulator of the basal secretion of follicle stimulating hormone (FSH) in a pituitary monolayer system. Biochemical and Biophysical Research Communications. 135: 950-6. PMID 3083816 DOI: 10.1016/0006-291X(86)91020-X  1
1986 Ling N, Guillemin R. hpGRF-44-NH2, lot no. 92-81-5G-41-47, is (human) growth hormone-releasing factor containing no trace of (ovine) corticotropin-releasing factor. Endocrinology. 118: 1249-51. PMID 3081328 DOI: 10.1210/endo-118-3-1249  1
1986 Bloch B, Baird A, Ling N, Guillemin R. Immunohistochemical evidence that growth hormone-releasing factor (GRF) neurons contain an amidated peptide derived from cleavage of the carboxyl-terminal end of the GRF precursor. Endocrinology. 118: 156-62. PMID 3079700 DOI: 10.1210/endo-118-1-156  1
1986 Matsuki A, Kudo T, Ishihara H, Jin T, Taneichi T, Oyama T, Guillemin R, Ling N. Plasma beta-endorphin levels during obstetrical analgesia with synthetic beta-endorphin. Agressologie: Revue Internationale De Physio-Biologie Et De Pharmacologie AppliquéEs Aux Effets De L'Agression. 27: 133-7. PMID 2945448  1
1986 Montesano R, Vassalli JD, Baird A, Guillemin R, Orci L. Basic fibroblast growth factor induces angiogenesis in vitro. Proceedings of the National Academy of Sciences of the United States of America. 83: 7297-301. PMID 2429303 DOI: 10.1073/pnas.83.19.7297  1
1986 Mason AJ, Hayflick JS, Ling N, Esch F, Ueno N, Ying SY, Guillemin R, Niall H, Seeburg PH. Complementary DNA sequences of ovarian follicular fluid inhibin show precursor structure and homology with transforming growth factor-β Obstetrical and Gynecological Survey. 41: 444-445.  1
1985 Esch F, Ueno N, Baird A, Hill F, Denoroy L, Ling N, Gospodarowicz D, Guillemin R. Primary structure of bovine brain acidic fibroblast growth factor (FGF). Biochemical and Biophysical Research Communications. 133: 554-62. PMID 4084288 DOI: 10.1016/0006-291X(85)90942-8  1
1985 Guillemin R. Walter B. Cannon memorial lecture. The language of polypeptides and the wisdom of the body. The Physiologist. 28: 391-6. PMID 4070376  1
1985 Baird A, Böhlen P, Ling N, Guillemin R. Radioimmunoassay for fibroblast growth factor (FGF): release by the bovine anterior pituitary in vitro. Regulatory Peptides. 10: 309-17. PMID 4039829 DOI: 10.1016/0167-0115(85)90043-6  1
1985 Baird A, Mormède P, Ying SY, Wehrenberg WB, Ueno N, Ling N, Guillemin R. A nonmitogenic pituitary function of fibroblast growth factor: regulation of thyrotropin and prolactin secretion. Proceedings of the National Academy of Sciences of the United States of America. 82: 5545-9. PMID 3927303 DOI: 10.1073/pnas.82.16.5545  1
1985 Baird A, Esch F, Gospodarowicz D, Guillemin R. Retina- and eye-derived endothelial cell growth factors: partial molecular characterization and identity with acidic and basic fibroblast growth factors. Biochemistry. 24: 7855-60. PMID 3912009  1
1985 Ling N, Ying SY, Ueno N, Esch F, Denoroy L, Guillemin R. Isolation and partial characterization of a Mr 32,000 protein with inhibin activity from porcine follicular fluid. Proceedings of the National Academy of Sciences of the United States of America. 82: 7217-21. PMID 3864157 DOI: 10.1073/pnas.82.21.7217  1
1985 Esch F, Baird A, Ling N, Ueno N, Hill F, Denoroy L, Klepper R, Gospodarowicz D, Böhlen P, Guillemin R. Primary structure of bovine pituitary basic fibroblast growth factor (FGF) and comparison with the amino-terminal sequence of bovine brain acidic FGF. Proceedings of the National Academy of Sciences of the United States of America. 82: 6507-11. PMID 3863109 DOI: 10.1073/pnas.82.19.6507  1
1985 Ling N, Zeytin F, Böhlen P, Esch F, Brazeau P, Wehrenberg WB, Baird A, Guillemin R. Growth hormone releasing factors. Annual Review of Biochemistry. 54: 403-23. PMID 2992358 DOI: 10.1146/annurev.bi.54.070185.002155  0.84
1985 Benoit R, Bohlen P, Ling N, Esch F, Baird A, Ying SY, Wehrenberg WB, Guillemin R, Morrison JH, Bakhit C. Somatostatin-28 [1-12]-like peptides. Advances in Experimental Medicine and Biology. 188: 89-107. PMID 2863951  1
1985 Wehrenberg WB, Baird A, Zeytin F, Esch F, Böhlen P, Ling N, Ying SY, Guillemin R. Physiological studies with somatocrinin, a growth hormone-releasing factor. Annual Review of Pharmacology and Toxicology. 25: 463-83. PMID 2860847 DOI: 10.1146/annurev.pa.25.040185.002335  1
1985 Mason AJ, Hayflick JS, Ling N, Esch F, Ueno N, Ying SY, Guillemin R, Niall H, Seeburg PH. Complementary DNA sequences of ovarian follicular fluid inhibin show precursor structure and homology with transforming growth factor-beta. Nature. 318: 659-63. PMID 2417121 DOI: 10.1038/318659a0  1
1985 Baird A, Culler F, Jones KL, Guillemin R. Angiogenic factor in human ocular fluid. Lancet (London, England). 2: 563. PMID 2412079 DOI: 10.1016/S0140-6736(85)90512-4  1
1984 Hatron PY, Wemeau JL, Guillemin R, Raviart B, Vanhille P, Devulder B. [Thyroid function in the nephrotic syndrome]. La Revue De MéDecine Interne / FondéE ... Par La SociéTé Nationale Francaise De MéDecine Interne. 5: 35-42. PMID 6718837 DOI: 10.1016/S0248-8663(84)80076-4  1
1984 Böhlen P, Wehrenberg WB, Esch F, Ling N, Brazeau P, Guillemin R. Rat hypothalamic growth hormone-releasing factor: isolation, sequence analysis and total synthesis. Biochemical and Biophysical Research Communications. 125: 1005-12. PMID 6440563 DOI: 10.1016/0006-291X(84)91383-4  1
1984 Brazeau P, Böhlen P, Esch F, Ling N, Wehrenberg WB, Guillemin R. Growth hormone-releasing factor from ovine and caprine hypothalamus: isolation, sequence analysis and total synthesis. Biochemical and Biophysical Research Communications. 125: 606-14. PMID 6440561 DOI: 10.1016/0006-291X(84)90582-5  1
1984 Ling N, Esch F, Böhlen P, Brazeau P, Wehrenberg WB, Guillemin R. Isolation, primary structure, and synthesis of human hypothalamic somatocrinin: growth hormone-releasing factor. Proceedings of the National Academy of Sciences of the United States of America. 81: 4302-6. PMID 6431406  0.84
1984 Guillemin R, Zeytin F, Ling N, Böhlen P, Esch F, Brazeau P, Bloch B, Wehrenberg WB. Growth hormone-releasing factor: chemistry and physiology. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 175: 407-13. PMID 6424128  1
1984 Bloch B, Ling N, Benoit R, Wehrenberg WB, Guillemin R. Specific depletion of immunoreactive growth hormone-releasing factor by monosodium glutamate in rat median eminence. Nature. 307: 272-3. PMID 6420704 DOI: 10.1038/307272a0  1
1984 Esch F, Ling N, Bohlen P, Baird A, Benoit R, Guillemin R. Isolation and characterization of the bovine hypothalamic corticotropin-releasing factor. Biochemical and Biophysical Research Communications. 122: 899-905. PMID 6332625 DOI: 10.1016/0006-291X(84)91175-6  1
1984 Ling N, Esch F, Böhlen P, Baird A, Guillemin R. Isolation and characterization of caprine corticotropin-releasing factor. Biochemical and Biophysical Research Communications. 122: 1218-24. PMID 6332624 DOI: 10.1016/0006-291X(84)91222-1  1
1984 Wehrenberg WB, Baird A, Ying SY, Rivier C, Ling N, Guillemin R. Multiple stimulation of the adenohypophysis by combinations of hypothalamic releasing factors. Endocrinology. 114: 1995-2001. PMID 6327231 DOI: 10.1210/endo-114-6-1995  1
1984 Guillemin R, Brazeau P, Böhlen P, Esch F, Ling N, Wehrenberg WB, Bloch B, Mougin C, Zeytin F, Baird A. Somatocrinin, the growth hormone releasing factor. Recent Progress in Hormone Research. 40: 233-99. PMID 6148773  1
1984 Wehrenberg WB, Bloch B, Chong-Li Z, Brazeau P, Ling N, Guillemin R. Pituitary response to growth hormone-releasing factor in rats with functional or anatomical lesions of the central nervous system that inhibit endogenous growth hormone secretion. Regulatory Peptides. 8: 1-8. PMID 6144144 DOI: 10.1016/0167-0115(84)90023-5  1
1984 Wehrenberg WB, Brazeau P, Ling N, Textor G, Guillemin R. Pituitary growth hormone response in rats during a 24-hour infusion of growth hormone-releasing factor. Endocrinology. 114: 1613-6. PMID 6143658 DOI: 10.1210/endo-114-5-1613  1
1984 Mougin C, Brazeau P, Ling N, Lewin M, Guillemin R. [Roles of cyclic AMP and calcium in the mechanism of the release of growth hormone by somatocrinin]. Comptes Rendus De L'AcadéMie Des Sciences. SéRie Iii, Sciences De La Vie. 299: 83-8. PMID 6093953  0.84
1983 Esch FS, Ling NC, Böhlen P, Ying SY, Guillemin R. Primary structure of PDC-109, a major protein constituent of bovine seminal plasma. Biochemical and Biophysical Research Communications. 113: 861-7. PMID 6870895 DOI: 10.1016/0006-291X(83)91078-1  1
1983 Esch F, Böhlen P, Ling N, Brazeau P, Guillemin R. Isolation and characterization of the bovine hypothalamic growth hormone releasing factor. Biochemical and Biophysical Research Communications. 117: 772-9. PMID 6421287 DOI: 10.1016/0006-291X(83)91664-9  1
1983 Böhlen P, Esch F, Brazeau P, Ling N, Guillemin R. Isolation and characterization of the porcine hypothalamic growth hormone releasing factor. Biochemical and Biophysical Research Communications. 116: 726-34. PMID 6418166 DOI: 10.1016/0006-291X(83)90585-5  1
1983 Böhlen P, Brazeau P, Bloch B, Ling N, Gaillard R, Guillemin R. Human hypothalamic growth hormone releasing factor (GRF): evidence for two forms identical to tumor derived GRF-44-NH2 and GRF-40. Biochemical and Biophysical Research Communications. 114: 930-6. PMID 6412708 DOI: 10.1016/0006-291X(83)90649-6  1
1983 Wehrenberg WB, Benoit R, Baird A, Guillemin R. Inhibitory effects of cysteamine on neuroendocrine function. Regulatory Peptides. 6: 137-45. PMID 6410461 DOI: 10.1016/0167-0115(83)90006-X  1
1983 Rosenthal SM, Schriock EA, Kaplan SL, Guillemin R, Grumbach MM. Synthetic human pancreas growth hormone-releasing factor (hpGRF1-44-NH2) stimulates growth hormone secretion in normal men. The Journal of Clinical Endocrinology and Metabolism. 57: 677-9. PMID 6409919 DOI: 10.1210/jcem-57-3-677  1
1983 Bloch B, Brazeau P, Ling N, Bohlen P, Esch F, Wehrenberg WB, Benoit R, Bloom F, Guillemin R. Immunohistochemical detection of growth hormone-releasing factor in brain. Nature. 301: 607-8. PMID 6402707 DOI: 10.1038/301607a0  1
1983 Bloch B, Baird A, Ling N, Benoit R, Guillemin R. Immunohistochemical evidence that brain enkephalins arise from a precursor similar to adrenal preproenkephalin. Brain Research. 263: 251-7. PMID 6340794 DOI: 10.1016/0006-8993(83)90317-7  1
1983 Böhlen P, Brazeau P, Esch F, Ling N, Wehrenberg WB, Guillemin R. Human growth hormone releasing factor and somatostatin from two pancreatic tumors: isolation and characterization. Regulatory Peptides. 6: 343-53. PMID 6138818 DOI: 10.1016/0167-0115(83)90263-X  1
1983 Wehrenberg WB, Brazeau P, Luben R, Ling N, Guillemin R. A noninvasive functional lesion of the hypothalamo-pituitary axis for the study of growth hormone-releasing factor. Neuroendocrinology. 36: 489-91. PMID 6136006 DOI: 10.1159/000123504  1
1983 Ravazzola M, Benoit R, Ling N, Guillemin R, Orci L. Immunocytochemical localization of prosomatostatin fragments in maturing and mature secretory granules of pancreatic and gastrointestinal D cells. Proceedings of the National Academy of Sciences of the United States of America. 80: 215-8. PMID 6130530  1
1983 Esch FS, Böhlen P, Ling NC, Brazeau PE, Wehrenberg WB, Guillemin R. Primary structures of three human pancreas peptides with growth hormone-releasing activity. The Journal of Biological Chemistry. 258: 1806-12. PMID 6130096  1
1982 Esch FS, Böhlen P, Ling NC, Brazeau PE, Wehrenberg WB, Thorner MO, Cronin MJ, Guillemin R. Characterization of a 40 residue peptide from a human pancreatic tumor with growth hormone releasing activity. Biochemical and Biophysical Research Communications. 109: 152-8. PMID 7159418 DOI: 10.1016/0006-291X(82)91578-9  1
1982 Benoit R, Ling N, Bakhit C, Morrison JH, Alford B, Guillemin R. Somatostatin-28(1-12)-like immunoreactivity in the rat. Endocrinology. 111: 2149-51. PMID 7140652 DOI: 10.1210/endo-111-6-2149  1
1982 Baird A, Ling N, Böhlen P, Benoit R, Klepper R, Guillemin R. Molecular forms of the putative enkephalin precursor BAM-12P in bovine adrenal, pituitary, and hypothalamus. Proceedings of the National Academy of Sciences of the United States of America. 79: 2023-5. PMID 6952250 DOI: 10.1073/pnas.79.6.2023  1
1982 Brazeau P, Guillemin R, Ling N, van Wyk J, Humbel R. [Somatomedin inhibition of the growth hormone secretion stimulated by the hypothalamic factor somatocrinin or the synthetic peptide hpGRF]. Comptes Rendus Des SéAnces De L'AcadéMie Des Sciences. SéRie Iii, Sciences De La Vie. 295: 651-4. PMID 6819872  1
1982 Wehrenberg WB, Ling N, Brazeau P, Esch F, Böhlen P, Baird A, Ying S, Guillemin R. Somatocrinin, growth hormone releasing factor, stimulates secretion of growth hormone in anesthetized rats. Biochemical and Biophysical Research Communications. 109: 382-7. PMID 6817757 DOI: 10.1016/0006-291X(82)91732-6  1
1982 Ying SY, Ling NC, Esch FS, Guillemin R, Watkins WB. Purification of gonadostatin from bovine seminal plasma (BSP). Advances in Experimental Medicine and Biology. 147: 117-34. PMID 6817601  1
1982 Luben RA, Brazeau P, Böhlen P, Guillemin R. Monoclonal antibodies to hypothalamic growth hormone-releasing factor with picomoles of antigen. Science (New York, N.Y.). 218: 887-9. PMID 6813967  1
1982 Guillemin R, Brazeau P, Böhlen P, Esch F, Ling N, Wehrenberg WB. Growth hormone-releasing factor from a human pancreatic tumor that caused acromegaly. Science (New York, N.Y.). 218: 585-7. PMID 6812220 DOI: 10.1126/science.6812220  1
1982 Brazeau P, Ling N, Esch F, Böhlen P, Mougin C, Guillemin R. Somatocrinin (growth hormone releasing factor) in vitro bioactivity; Ca++ involvement, cAMP mediated action and additivity of effect with PGE2. Biochemical and Biophysical Research Communications. 109: 588-94. PMID 6185122 DOI: 10.1016/0006-291X(82)91762-4  1
1982 Brazeau P, Ling N, Böhlen P, Esch F, Ying SY, Guillemin R. Growth hormone releasing factor, somatocrinin, releases pituitary growth hormone in vitro. Proceedings of the National Academy of Sciences of the United States of America. 79: 7909-13. PMID 6130528 DOI: 10.1073/pnas.79.24.7909  1
1982 Wehrenberg WB, Ling N, Böhlen P, Esch F, Brazeau P, Guillemin R. Physiological roles of somatocrinin and somatostatin in the regulation of growth hormone secretion. Biochemical and Biophysical Research Communications. 109: 562-7. PMID 6129852 DOI: 10.1016/0006-291X(82)91758-2  1
1982 Guillemin R. The brain as an endocrine organ--update 1981. Endocrinologia Experimentalis. 16: 151-62. PMID 6129125  1
1982 Wehrenberg WB, Brazeau P, Luben R, Böhlen P, Guillemin R. Inhibition of the pulsatile secretion of growth hormone by monoclonal antibodies to the hypothalamic growth hormone releasing factor (GRF). Endocrinology. 111: 2147-8. PMID 6128220 DOI: 10.1210/endo-111-6-2147  1
1982 Benoit R, Ling N, Alford B, Guillemin R. Seven peptides derived from pro-somatostatin in rat brain. Biochemical and Biophysical Research Communications. 107: 944-50. PMID 6127997 DOI: 10.1016/0006-291X(82)90614-3  1
1982 Benoit R, Böhlen P, Ling N, Briskin A, Esch F, Brazeau P, Ying SY, Guillemin R. Presence of somatostatin-28-(1-12) in hypothalamus and pancreas. Proceedings of the National Academy of Sciences of the United States of America. 79: 917-21. PMID 6121326  1
1981 Böhlen P, Esch F, Shibasaki T, Baird A, Ling N, Guillemin R. Isolation and characterization of a gamma 1-melanotropin-like peptide from bovine neurointermediate pituitary. Febs Letters. 128: 67-70. PMID 7274457 DOI: 10.1016/0014-5793(80)81133-1  1
1981 Shibasaki T, Ling N, Guillemin R, Silver M, Bloom F. The regional distribution of gamma 3-melanotropin-like peptides in bovine brain is correlated with adrenocorticotropin immunoreactivity but not with beta-endorphin. Regulatory Peptides. 2: 43-52. PMID 6262881 DOI: 10.1016/0167-0115(81)90064-1  1
1981 Shibasaki T, Masui H, Sato G, Ling N, Guillemin R. Secretion pattern of pro-opiomelanocortin-derived peptides by a pituitary adenoma from a patient with Cushing's disease. The Journal of Clinical Endocrinology and Metabolism. 52: 350-3. PMID 6257745 DOI: 10.1210/jcem-52-2-350  1
1981 Ying SY, Ling N, Böhlen P, Guillemin R. Gonadocrinins: peptides in ovarian follicular fluid stimulating the secretion of pituitary gonadotropins. Endocrinology. 108: 1206-15. PMID 6162633 DOI: 10.1210/endo-108-4-1206  0.6
1981 Böhlen P, Brazeau P, Esch F, Ling N, Guillemin R. Isolation and chemical characterization of somatostatin-28 from rat hypothalamus. Regulatory Peptides. 2: 359-69. PMID 6117931  0.84
1981 Guillemin R. Hypothalamic hypophysiotrophic peptides, known and unknown. The Sir Henry Dale lecture for 1980. The Journal of Endocrinology. 90: 3p-10p. PMID 6114978  1
1981 Brazeau P, Ling N, Esch F, Böhlen P, Benoit R, Guillemin R. High biological activity of the synthetic replicates of somatostatin-28 and somatostatin-25. Regulatory Peptides. 1: 255-64. PMID 6114516  0.84
1981 Lavielle S, Ling NC, Saltman R, Guillemin RC. Synthesis of a glycotripeptide and a glycosomatostatin containing the 3-O-(2-acetamido-2-deoxy-beta-D-glucopyranosyl)-L-serine residue. Carbohydrate Research. 89: 229-36. PMID 6113052 DOI: 10.1016/S0008-6215(00)85248-9  1
1981 Lavielle S, Ling NC, Guillemin RC. Solid-phase synthesis of two glycopeptides containing the amino acid sequence 5 to 9 of somatostatin. Carbohydrate Research. 89: 221-8. PMID 6113051 DOI: 10.1016/S0008-6215(00)85247-7  1
1981 Mandarino L, Stenner D, Blanchard W, Nissen S, Gerich J, Ling N, Brazeau P, Bohlen P, Esch F, Guillemin R. Selective effects of somatostatin-14, -25 and -28 on in vitro insulin and glucagon secretion. Nature. 291: 76-7. PMID 6112710 DOI: 10.1038/291076a0  1
1981 Bohlen P, Benoit R, Ling N, Guillemin R, Brazeau P. Isolation and characterization of rat hypothalamic somatostatin-14. Endocrinology. 108: 2008-10. PMID 6111447 DOI: 10.1210/endo-108-5-2008  1
1981 Böhlen P, Esch F, Shibasaki T, Baird A, Ling N, Guillemin R. Isolation and characterization of a γ1-melanotropin-like peptide from bovine neurointermediate pituitary Febs Letters. 128: 67-70. DOI: 10.1016/0014-5793(81)81081-2  1
1980 Böhlen P, Castillo F, Ling N, Guillemin R. Purification of peptides: an efficient procedure for the separation of peptides from amino acids and salt. International Journal of Peptide and Protein Research. 16: 306-10. PMID 7461910  0.6
1980 Shibasaki T, Ling N, Guillemin R. A radioimmunoassay for gamma 1-melanotropin and evidence that the smallest pituitary gamma-melanotropin is amidated at the COOH-terminus. Biochemical and Biophysical Research Communications. 96: 1393-9. PMID 7437077  0.6
1980 Oyama T, Matsuki A, Taneichi T, Ling N, Guillemin R. beta-Endorphin in obstetric analgesia. American Journal of Obstetrics and Gynecology. 137: 613-6. PMID 6892978  0.6
1980 Bloom FE, Battenberg EL, Shibasaki T, Benoit R, Ling N, Guillemin R. Localization of gamma-melanocyte stimulating hormone (gamma MSH) immunoreactivity in rat brain and pituitary. Regulatory Peptides. 1: 205-22. PMID 6262877  0.64
1980 Rossier J, French E, Guillemin R, Bloom FE. On the mechanisms of the simultaneous release of immunoreactive beta-endorphin, ACTH, and prolactin by stress. Advances in Biochemical Psychopharmacology. 22: 363-75. PMID 6249081  0.56
1980 Shibasaki T, Ling N, Guillemin R. A radioimmunoassay for gamma-melanocyte stimulating hormone. Life Sciences. 26: 1781-5. PMID 6248714  0.6
1980 Julliard JH, Shibasaki T, Ling N, Guillemin R. High-molecular-weight immunoreactive beta-endorphin in extracts of human placenta is a fragment of immunoglobulin G. Science (New York, N.Y.). 208: 183-5. PMID 6244620  0.6
1980 Rossier J, French E, Rivier C, Shibasaki T, Guillemin R, Bloom FE. Stress-induced release of prolactin: blockade by dexamethasone and naloxone may indicate beta-endorphin mediation. Proceedings of the National Academy of Sciences of the United States of America. 77: 666-9. PMID 6244573  1
1980 Esch F, Böhlen P, Ling N, Benoit R, Brazeau P, Guillemin R. Primary structure of ovine hypothalamic somatostatin-28 and somatostatin-25. Proceedings of the National Academy of Sciences of the United States of America. 77: 6827-31. PMID 6109284  0.84
1980 Benoit R, Böhlen P, Brazeau P, Ling N, Guillemin R. Isolation and characterization of rat pancreatic somatostatin. Endocrinology. 107: 2127-9. PMID 6107246 DOI: 10.1210/endo-107-6-2127  0.84
1980 Böhlen P, Brazeau P, Benoit R, Ling N, Esch F, Guillemin R. Isolation and amino acid composition of two somatostatin-like peptides from ovine hypothalamus: somatostatin-28 and somatostatin-25. Biochemical and Biophysical Research Communications. 96: 725-34. PMID 6107078  0.84
1980 Ling N, Esch F, Davis D, Mercado M, Regno M, Bohlen P, Brazeau P, Guillemin R. Solid phase synthesis of somatostatin-28. Biochemical and Biophysical Research Communications. 95: 945-51. PMID 6106480  0.84
1980 Brazeau P, Ling N, Esch F, Bohlen P, Benoît R, Guillemin R. [High biological activity of the synthetic counterparts of hypothalamic somatostatin-28 and somatostatin-25]. Comptes Rendus Des SéAnces De L'AcadéMie Des Sciences. SéRie D, Sciences Naturelles. 290: 1369-71. PMID 6105927  0.84
1980 Rossier J, Pittman Q, Bloom F, Guillemin R. Distribution of opioid peptides in the pituitary: a new hypothalamic-pars nervosa enkephalinergic pathway. Federation Proceedings. 39: 2555-60. PMID 6103825  0.52
1980 Oyama T, Jin T, Yamaya R, Ling N, Guillemin R. Profound analgesic effects of beta-endorphin in man. Lancet (London, England). 1: 122-4. PMID 6101459  0.6
1980 Shibasaki T, Ling N, Guillemin R. Pituitary immunoreactive gamma-melanotropins are glycosylated oligopeptides. Nature. 285: 416-7. PMID 6101229  0.6
1979 Rossier J, French E, Gros C, Minick S, Guillemin R, Bloom FE. Adrenalectomy, dexamethasone or stress alters opioid peptides levels in rat anterior pituitary but not intermediate lobe or brain. Life Sciences. 25: 2105-12. PMID 537470  0.56
1979 Lavielle S, Ling N, Brazeau P, Benoit R, Wasada T, Harris D, Unger R, Guillemin R. Synthesis and biological activity of glycosylated analogs of somatostatin. Biochemical and Biophysical Research Communications. 91: 614-22. PMID 518658  0.84
1979 Orloff MJ, Hyde PV, Kosta LD, Guillemin RC, Bell RH. The intestinal phase hormone. World Journal of Surgery. 3: 523-38. PMID 516773 DOI: 10.1007/BF01654753  1
1979 Bayon A, Shoemaker WJ, Bloom FE, Mauss A, Guillemin R. Perinatal development of the endorphin- and enkephalin-containing systems in the rat brain. Brain Research. 179: 93-101. PMID 509236  0.56
1979 Chorev M, Shavitz R, Goodman M, Minick S, Guillemin R. Partially modified retro-inverso-enkephalinamides: topochemical long-acting analogs in vitro and in vivo. Science (New York, N.Y.). 204: 1210-2. PMID 451565  0.52
1979 Ying SY, Guillemin R. Dried Staphylococcus aureus as a rapid immunological separating agent in radioimmunoassays. The Journal of Clinical Endocrinology and Metabolism. 48: 360-2. PMID 429490 DOI: 10.1210/jcem-48-2-360  0.48
1979 Rossier J, Rogers J, Shibasaki T, Guillemin R, Bloom FE. Opioid peptides and alpha-melanocyte-stimulating hormone in genetically obese (ob/ob) mice during development. Proceedings of the National Academy of Sciences of the United States of America. 76: 2077-80. PMID 287046  0.56
1979 Ling N, Ying S, Minick S, Guillemin R. Synthesis and biological activity of four gamma-melanotropin peptides derived from the cryuptic region of the adrenocorticotropin/beta-lipotropin precursor. Life Sciences. 25: 1773-9. PMID 231164  0.6
1979 Shibasaki T, Deftos L, Guillemin R. Immunoreactive-beta-endorphin, -adrenocorticotropin and -calcitonin in extracts of anaplastic or differentiated (rat) medullary thyroid carcinoma. Biochemical and Biophysical Research Communications. 90: 1266-73. PMID 229834  0.52
1979 Ying SY, Guillemin R. DTrp6-Pro9-NEt)-luteinising hormone-releasing factor inhibits follicular development in hypophysectomised rats. Nature. 280: 593-5. PMID 223068  0.48
1979 Ying SY, Guillemin R. [Gonadostatin and gonadocrinin, polypeptides of ovarian origin with hypophysiotropic activity]. Comptes Rendus Des SéAnces De L'AcadéMie Des Sciences. SéRie D, Sciences Naturelles. 289: 943-6. PMID 121254  0.48
1979 Hosobuchi Y, Rossier J, Bloom FE, Guillemin R. Stimulation of human periaqueductal gray for pain relief increases immunoreactive beta-endorphin in ventricular fluid. Science (New York, N.Y.). 203: 279-81. PMID 83674  0.56
1979 Rossier J, Battenberg E, Pittman Q, Bayon A, Koda L, Miller R, Guillemin R, Bloom F. Hypothalamic enkephalin neurones may regulate the neurohypophysis. Nature. 277: 653-5. PMID 34105  0.56
1978 Ling N, Minick S, Guillemin R. Amino-terminal extension analogs of methionine-enkephalin. Biochemical and Biophysical Research Communications. 83: 565-70. PMID 697841  0.6
1978 Rossier J, Guillemin R, Bloom F. Foot shock induced stress decreases leu5-enkephalin immunoreactivity in rat hypothalamus. European Journal of Pharmacology. 48: 465-6. PMID 565718  0.52
1978 Hyde PV, Skivolocki WP, Guillemin RC, Sayers HJ, Orloff MJ. Augmentation of pentagastrin- and gastrin-stimulated acid secretion by the intestinal phase hormone. Surgical Forum. 29: 392-4. PMID 401203  1
1978 Deftos LJ, Burton D, Catherwood BD, Bone HG, Parthemore JG, Guillemin R, Watkins WB, Moore RY. Demonstration by immunoperoxidase histochemistry of calcitonin in the anterior lobe of the rat pituitary. The Journal of Clinical Endocrinology and Metabolism. 47: 457-60. PMID 400721 DOI: 10.1210/jcem-47-2-457  1
1978 Deftos LJ, Burton D, Bone HG, Catherwood BD, Parthemore JG, Moore RY, Minick S, Guillemin R. Immunoreactive calcitonin in the intermediate lobe of the pituitary gland. Life Sciences. 23: 743-8. PMID 357878 DOI: 10.1016/0024-3205(78)90073-5  1
1978 Bloom F, Battenberg E, Rossier J, Ling N, Guillemin R. Neurons containing beta-endorphin in rat brain exist separately from those containing enkephalin: immunocytochemical studies. Proceedings of the National Academy of Sciences of the United States of America. 75: 1591-5. PMID 349568  0.6
1978 Henriksen SJ, Bloom FE, McCoy F, Ling N, Guillemin R. beta-Endorphin induces nonconvulsive limbic seizures. Proceedings of the National Academy of Sciences of the United States of America. 75: 5221-5. PMID 283426  1
1978 Bayon A, Rossier J, Mauss A, Bloom FE, Iversen LL, Ling N, Guillemin R. In vitro release of [5-methionine]enkephalin and [5-leucine]-enkephalin from the rat globus pallidus. Proceedings of the National Academy of Sciences of the United States of America. 75: 3503-6. PMID 277953  0.6
1978 Orth DN, Guillemin R, Ling N, Nicholson WE. Immunoreactive endorphins, lipotropins and corticotropins in a human nonpituitary tumor: evidence for a common precursor. The Journal of Clinical Endocrinology and Metabolism. 46: 849-52. PMID 233636 DOI: 10.1210/jcem-46-5-849  0.6
1978 Vale W, Rivier C, Yang L, Minick S, Guillemin R. Effects of purified hypothalamic corticotropin-releasing factor and other substances on the secretion of adrenocorticotropin and beta-endorphin-like immunoactivities in vitro. Endocrinology. 103: 1910-5. PMID 218793 DOI: 10.1210/endo-103-5-1910  1
1978 Bloom FE, Rossier J, Battenberg EL, Bayon A, French E, Henriksen SJ, Siggins GR, Segal D, Browne R, Ling N, Guillemin R. beta-endorphin: cellular localization, electrophysiological and behavioral effects. Advances in Biochemical Psychopharmacology. 18: 89-109. PMID 77124  1
1978 Iversen LL, Iversen SD, Bloom FE, Vargo T, Guillemin R. Release of enkephalin from rat globus pallidus in vitro. Nature. 271: 679-81. PMID 24182  0.56
1977 Rossier J, Bayon A, Vargo TM, Ling N, Guillemin R, Bloom F. Radioimmunoassay of brain peptides: evaluation of a methodology for the assay of beta-endorphin and enkephalin. Life Sciences. 21: 847-52. PMID 916802  0.6
1977 Weitzman RE, Fisher DA, Minick S, Ling N, Guillemin R. beta-Endorphin secretion of arginine vasopressin in vivo. Endocrinology. 101: 1643-6. PMID 913330 DOI: 10.1210/endo-101-5-1643  0.6
1977 Segal DS, Browne RG, Bloom F, Ling N, Guillemin R. beta-Endorphin: endogenous opiate or neuroleptic? Science (New York, N.Y.). 198: 411-4. PMID 910136  1
1977 Guillemin R, Ling N, Burgus R, Bloom F, Segal D. Characterization of the endorphins, novel hypothalamic and neurohypophysial peptides with opiate-like activity: evidence that they induce profound behavioral changes. Psychoneuroendocrinology. 2: 59-62. PMID 905475  0.88
1977 Guillemin R, Ling N, Vargo T. Radioimmunoassays for alpha-endorphin and beta-endorphin. Biochemical and Biophysical Research Communications. 77: 361-6. PMID 883982  0.6
1977 Janowsky DS, Segal DS, Bloom F, Abrams A, Guillemin R. Lack of effect on naloxone on schizophrenic symptoms. The American Journal of Psychiatry. 134: 926-7. PMID 879360  1
1977 Bloom F, Battenberg E, Rossier J, Ling N, Leppaluoto J, Vargo TM, Guillemin R. Endorphins are located in the intermediate and anterior lobes of the pituitary gland, not in the neurohypophysis. Life Sciences. 20: 43-7. PMID 319317  0.6
1977 Guillemin R, Ling N, Lazarus L, Burgus R, Minick S, Bloom F, Nicoll R, Siggins G, Segal D. The endorphins, novel peptides of brain and hypophysial origin, with opiate-like activity: biochemical and biologic studies. Annals of the New York Academy of Sciences. 297: 131-57. PMID 279259  0.88
1977 Rossier J, Vargo TM, Minick S, Ling N, Bloom FE, Guillemin R. Regional dissociation of beta-endorphin and enkephalin contents in rat brain and pituitary. Proceedings of the National Academy of Sciences of the United States of America. 74: 5162-5. PMID 270754  0.6
1977 Nicoll RA, Siggins GR, Ling N, Bloom FE, Guillemin R. Neuronal actions of endorphins and enkephalins among brain regions: a comparative microiontophoretic study. Proceedings of the National Academy of Sciences of the United States of America. 74: 2584-8. PMID 267951  1
1977 Rossier J, French ED, Rivier C, Ling N, Guillemin R, Bloom FE. Foot-shock induced stress increases beta-endorphin levels in blood but not brain. Nature. 270: 618-20. PMID 201864 DOI: 10.1038/270618a0  1
1977 Kan KW, Baird A, Seidah NG, Lis M, Chrétien M, Ling N, Guillemin R, Solomon S. Effects of peptides of pituitary origin on the formation of C21 steroid by fetal calf adrenal cells in culture. Biochemical and Biophysical Research Communications. 79: 553-60. PMID 201254 DOI: 10.1016/0006-291X(77)90193-0  1
1977 Guillemin R, Vargo T, Rossier J, Minick S, Ling N, Rivier C, Vale W, Bloom F. beta-Endorphin and adrenocorticotropin are selected concomitantly by the pituitary gland. Science (New York, N.Y.). 197: 1367-9. PMID 197601  1
1977 Rivier C, Vale W, Ling N, Brown M, Guillemin R. Stimulation in vivo of the secretion of prolactin and growth hormone by beta-endorphin. Endocrinology. 100: 238-41. PMID 187406 DOI: 10.1210/endo-100-1-238  1
1977 Janowsky DS, Segal DS, Abrams A, Bloom F, Guillemin R. Negative naloxone effects in schizophrenic patients. Psychopharmacology. 53: 295-7. PMID 19807 DOI: 10.1007/BF00492367  1
1976 Ling N, Burgus R, Guillemin R. Isolation, primary structure, and synthesis of alpha-endorphin and gamma-endorphin, two peptides of hypothalamic-hypophysial origin with morphinomimetic activity. Proceedings of the National Academy of Sciences of the United States of America. 73: 3942-6. PMID 1069261  0.88
1976 Ling N, Guillemin R. Morphinomimetic activity of synthetic fragments of beta-lipotropin and analogs. Proceedings of the National Academy of Sciences of the United States of America. 73: 3308-10. PMID 1067621  1
1976 Lazarus LH, Ling N, Guillemin R. beta-Lipotropin as a prohormone for the morphinomimetic peptides endorphins and enkephalins. Proceedings of the National Academy of Sciences of the United States of America. 73: 2156-9. PMID 1064883  1
1976 Guillemin R, Ling N, Burgus R. [Endorphins, hypothalamic and neurohypophysial peptides with morphinomimetic activity: isolation and molecular structure of alpha-endorphin]. Comptes Rendus Hebdomadaires Des SéAnces De L'AcadéMie Des Sciences. SéRie D: Sciences Naturelles. 282: 783-5. PMID 817843  0.88
1976 Orci L, Baetens O, Rufener C, Brown M, Vale W, Guillemin R. Evidence for immunoreactive neurotensin in dog intestinal mucosa. Life Sciences. 19: 559-61. PMID 785139  1
1976 Bloom F, Segal D, Ling N, Guillemin R. Endorphins: profound behavioral effects in rats suggest new etiological factors in mental illness. Science (New York, N.Y.). 194: 630-2. PMID 185694  0.6
1975 Vale W, Brazeau P, Rivier C, Brown M, Boss B, Rivier J, Burgus R, Ling N, Guillemin R. Somatostatin. Recent Progress in Hormone Research. 31: 365-97. PMID 1105719  1
1975 Rivier J, Brazeau P, Vale W, Guillemin R. Somatostatin analogs. Relative importance of the disulfide bridge and of the Ala-Gly side chain for biological activity. Journal of Medicinal Chemistry. 18: 123-6. PMID 1091734  1
1975 Guillemin R, Fontaine M. [The historic role of insulin in the physiopathology of the metabolic complications from pancreatic diabetes. Therapeutic implications for somatostatin]. Comptes Rendus Hebdomadaires Des SéAnces De L'AcadéMie Des Sciences. SéRie D: Sciences Naturelles. 280: 2353-6. PMID 807423  1
1975 Brown M, Rivier J, Vale W, Guillemin R. Variability of the duration of inhibition of growth hormone release by Nalpha-acylated-des-(Ala1-Gly2)-H2somatostatin analogs. Biochemical and Biophysical Research Communications. 65: 752-6. PMID 807218  1
1974 Parker DC, Rossman LG, Siler TM, Rivier J, Yen SS, Guillemin R. Inhibition of the sleep-related peak in physiologic human growth hormone release by somatostatin. The Journal of Clinical Endocrinology and Metabolism. 38: 496-9. PMID 4815179 DOI: 10.1210/jcem-38-3-496  1
1974 Brazeau P, Rivier J, Vale W, Guillemin R. Inhibition of growth hormone secretion in the rat by synthetic somatostatin. Endocrinology. 94: 184-7. PMID 4808882 DOI: 10.1210/endo-94-1-184  1
1974 Brazeau P, Vale W, Burgus R, Guillemin R. Isolation of somatostatin (a somatotropin release inhibiting factor) of ovine hypothalamic origin. Canadian Journal of Biochemistry. 52: 1067-72. PMID 4609582  1
1974 Brazeau P, Vale W, Rivier J, Guillemin R. Acylated des-(Ala1-Gly2)-somatostatin analogs: prolonged inhibition of growth hormone secretion. Biochemical and Biophysical Research Communications. 60: 1202-7. PMID 4607622  1
1974 Gerich JE, Lorenzi M, Schneider V, Karam JH, Rivier J, Guillemin R, Forsham PH. Effects of somatostatin on plasma glucose and glucagon levels in human diabetes mellitus. Pathophysiologic and therapeutic implications. The New England Journal of Medicine. 291: 544-7. PMID 4604408 DOI: 10.1056/NEJM197409122911102  0.72
1974 Brazeau P, Vale W, Rivier J, Guillemin R. Biological potency of synthetic somatostatin in the oxidized and reduced form on the inhibition of secretion of growth hormone. Life Sciences. 15: 351-7. PMID 4549923  1
1974 Vale W, Rivier C, Brazeau P, Guillemin R. Effects of somatostatin on the secretion of thyrotropin and prolactin. Endocrinology. 95: 968-77. PMID 4213073 DOI: 10.1210/endo-95-4-968  1
1974 Siler TM, Yen SC, Vale W, Guillemin R. Inhibition by somatostatin on the release of TSH induced in man by thyrotropin-releasing factor. The Journal of Clinical Endocrinology and Metabolism. 38: 742-5. PMID 4207367 DOI: 10.1210/jcem-38-5-742  1
1973 Siler TM, VandenBerg G, Yen SS, Brazeau P, Vale W, Guillemin R. Inhibition of growth hormone release in humans by somatostatin. The Journal of Clinical Endocrinology and Metabolism. 37: 632-4. PMID 4742541 DOI: 10.1210/jcem-37-4-632  1
1973 Blackwell R, Vale W, Rivier C, Guillemin R. Effect of perphenazine on the secretion of prolactin in vivo and in vitro. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 142: 68-71. PMID 4683266  1
1973 Brazeau P, Vale W, Burgus R, Ling N, Butcher M, Rivier J, Guillemin R. Hypothalamic polypeptide that inhibits the secretion of immunoreactive pituitary growth hormone. Science (New York, N.Y.). 179: 77-9. PMID 4682131  1
1973 Ling N, Rivier J, Burgus R, Guillemin R. Direct sequence determination of ovine luteinizing hormone releasing factor by mass spectrometry. Biochemistry. 12: 5305-10. PMID 4586516  0.88
1973 Guillemin R, Amoss M, Blackwell R, Burgus R, Grant G, Ling N, Monahan M, Rivier J, Vale W. Polypeptide antagonists of the hypothalamic luteinizing hormone releasing factors. Journal of Reproduction and Fertility. Supplement. 18: 23-30. PMID 4580254  1
1973 Rivier J, Vale W, Burgus R, Ling N, Amoss M, Blackwell R, Guillemin R. Synthetic luteinizing hormone-releasing factor analogs. Series of short-chain amide LRF homologs converging to the amino terminus. Journal of Medicinal Chemistry. 16: 545-9. PMID 4577979  1
1973 Blackwell R, Vale W, Amoss M, Burgus R, Monahan M, Rivier J, Ling N, Guillemin R. Lack of effect of native or synthetic LRF on secretion of prolactin in vitro. The American Journal of Physiology. 224: 176-9. PMID 4566850  1
1973 Blackwell R, Amoss M, Vale W, Burgus R, Rivier J, Monahan M, Ling N, Guillemin R. Concomitant release of FSH and LH induced by native and synthetic LRF. The American Journal of Physiology. 224: 170-5. PMID 4566849  1
1973 Rebar R, Yen SS, VandenBerg G, Naftolin F, Ehara Y, Engblom S, Ryan KJ, Amoss M, Guillemin R. Gonadotropin responses to synthetic LRF: dose-response relationship in men. The Journal of Clinical Endocrinology and Metabolism. 36: 10-6. PMID 4564687 DOI: 10.1210/jcem-36-1-10  0.6
1973 Burgus R, Ling N, Butcher M, Guillemin R. Primary structure of somatostatin, a hypothalamic peptide that inhibits the secretion of pituitary growth hormone. Proceedings of the National Academy of Sciences of the United States of America. 70: 684-8. PMID 4514982  0.88
1973 Guillemin R, Vale W, Grant G. Chemistry of the hypothalamic releasing factors. Studies on structure-function relationships in TRF and LRF. Voprosy Biokhimii Mozga. 8: 141-76. PMID 4375346  1
1973 Vale W, Grant G, Guillemin R. Chemistry of the hypothalamic releasing factors--studies on structure-function relationships. Frontiers in Neuroendocrinology. 375-413. PMID 4369859  1
1973 Vale W, Blackwell R, Grant G, Guillemin R. TRF and thyroid hormones on prolactin secretion by rat anterior pituitary cells in vitro. Endocrinology. 93: 26-33. PMID 4351315 DOI: 10.1210/endo-93-1-26  1
1973 Rivier C, Vale W, Guillemin R. An in vivo corticotropin-releasing factor (CRF) assay based on plasma levels of radioimmunoassayable ACTH. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 142: 842-5. PMID 4348096  1
1973 Burgus R, Vale W, Rivier J, Monahan M, Ling N, Grant G, Amoss M, Guillemin R. Chemistry of hypothalamic releasing factors. Progress in Brain Research. 39: 41-51. PMID 4208048 DOI: 10.1016/S0079-6123(08)64065-0  1
1973 Rivier J, Brazeau P, Vale W, Ling N, Burgus R, Gilon C, Yardley J, Guillemin R. [Solid-phase total synthesis of a tetradecapeptide having the chemical and biological properties of somatostatine]. Comptes Rendus Hebdomadaires Des SéAnces De L'AcadéMie Des Sciences. SéRie D: Sciences Naturelles. 276: 2737-40. PMID 4198857  1
1973 Grant G, Vale W, Guillemin R. Characteristics of the pituitary binding sites for thyrotropin releasing factor. Endocrinology. 92: 1629-33. PMID 4196427 DOI: 10.1210/endo-92-6-1629  1
1972 Amoss M, Blackwell R, Guillemin R. Stimulation of ovulation in the rabbit triggered by synthetic LRF. The Journal of Clinical Endocrinology. 34: 434-6. PMID 12256596  0.72
1972 Vale W, Grant G, Amoss M, Blackwell R, Guillemin R. Culture of enzymatically dispersed pituitary cells: functional validation of a method. Endocrinology. 91: 562-72. PMID 4630101 DOI: 10.1210/endo-91-2-562  1
1972 Grant G, Vale W, Guillemin R. Interaction of thyrotropin releasing factor with membrane receptors of pituitary cells. Biochemical and Biophysical Research Communications. 46: 28-34. PMID 4621353  1
1972 Guillemin R, Amoss M, Blackwell R, Rivier J, Ling N, Vale W. On the biological activities of the synthetic tetrapeptide pyroglutamyl-tyrosyl-arginyl-tryptophanyl-amide. Biochemical and Biophysical Research Communications. 48: 1093-9. PMID 4560003  1
1972 Monahan MW, Rivier J, Vale W, Guillemin R, Burgus R. (Gly 2 )LRF and des-His 2 -LRF. The synthesis, purification, and characterization of two LRF analogues antagonistic to LRF. Biochemical and Biophysical Research Communications. 47: 551-6. PMID 4556826  1
1972 Vale W, Grant G, Rivier J, Monahan M, Amoss M, Blackwell R, Burgus R, Guillemin R. Synthetic polypeptide antagonists of the hypothalamic luteinizing hormone releasing factor. Science (New York, N.Y.). 176: 933-4. PMID 4555980  1
1972 Amoss M, Rivier J, Guillemin R. Release of gonadotropins by oral administration of synthetic LRF or a tripeptide fragment of LRF. The Journal of Clinical Endocrinology and Metabolism. 35: 175-7. PMID 4555782 DOI: 10.1210/jcem-35-1-175  0.72
1972 Yen SS, Rebar R, Van den Berg G, Naftolin F, Ehara Y, Engblom S, Ryan KJ, Benirschke K, Rivier J, Amoss M, Guillemin R. Synthetic luteinizing hormone-releasing factor. A potent stimulator of gonadotropin release in man. The Journal of Clinical Endocrinology and Metabolism. 34: 1108-11. PMID 4553517 DOI: 10.1210/jcem-34-6-1108  0.72
1972 Amoss M, Blackwell R, Guillemin R. Stimulation of ovulation in the rabbit triggered by synthetic LRF. The Journal of Clinical Endocrinology and Metabolism. 34: 434-6. PMID 4551071 DOI: 10.1210/jcem-34-2-434  0.72
1972 Burgus R, Butcher M, Amoss M, Ling N, Monahan M, Rivier J, Fellows R, Blackwell R, Vale W, Guillemin R. Primary structure of the ovine hypothalamic luteinizing hormone-releasing factor (LRF) (LH-hypothalamus-LRF-gas chromatography-mass spectrometry-decapeptide-Edman degradation). Proceedings of the National Academy of Sciences of the United States of America. 69: 278-82. PMID 4550508  1
1972 Fleischer N, Guillemin R. Clinical applications of hypothalamic-releasing factors. Advances in Internal Medicine. 18: 303-23. PMID 4351196  0.44
1972 Vale W, Brazeau P, Grant G, Nussey A, Burgus R, Rivier J, Ling N, Guillemin R. [Preliminary observations on the mechanism of action of somatostatin, a hypothalamic factor inhibiting the secretion of growth hormone]. Comptes Rendus Hebdomadaires Des SéAnces De L'AcadéMie Des Sciences. SéRie D: Sciences Naturelles. 275: 2913-6. PMID 4347575  1
1972 Guillemin R, Burgus R. The hormones of the hypothalamus. Scientific American. 227: 24-33. PMID 4145789  0.88
1971 Vale WW, Burgus R, Dunn TF, Guillemin R. In vitro plasma inactivation of thyrotropin releasing factor (TRF) and related peptides. Its inhibition by various means and by the synthetic dipeptide PCA-His-OME. Hormones. 2: 193-203. PMID 5006796  0.88
1971 Burgus R, Butcher M, Ling N, Monahan M, Rivier J, Fellows R, Amoss M, Blackwell R, Vale W, Guillemin R. [Molecular structure of the hypothalamic factor (LRF) of ovine origin monitoring the secretion of pituitary gonadotropic hormone of luteinization (LH)]. Comptes Rendus Hebdomadaires Des SéAnces De L'AcadéMie Des Sciences. SéRie D: Sciences Naturelles. 273: 1611-3. PMID 5002981  1
1971 Guillemin R, Burgus R, Vale W. The hypothalamic hypophysiotropic thyrotropin-releasing factor. Vitamins and Hormones. 29: 1-39. PMID 5002592  1
1971 Monahan M, Rivier J, Burgus R, Amoss M, Blackwell R, Vale W, Guillemin R. [Total synthesis by solid phase of a decapeptide stimulating the secretion of LH and FSH pituitary gonadotropins]. Comptes Rendus Hebdomadaires Des SéAnces De L'AcadéMie Des Sciences. SéRie D: Sciences Naturelles. 273: 508-10. PMID 4999985  1
1971 Porter JC, Vale W, Burgus R, Mical RS, Guillemin R. Release of TSH by TRF infused directly into a pituitary stalk portal vessel. Endocrinology. 89: 1054-6. PMID 4999143 DOI: 10.1210/endo-89-4-1054  1
1971 Guillemin R, Amoss M, Blackwell R, Burgus R, Grant G, Ling N, Monahan M, Rivier J, Vale W. Polypeptides antagonists of the hypothalamic luteinizing hormone releasing factor. Gynecologic Investigation. 2: 2-12. PMID 4949825  1
1971 Amoss M, Burgus R, Blackwell R, Vale W, Fellows R, Guillemin R. Purification, amino acid composition and N-terminus of the hypothalamic luteinizing hormone releasing factor (LRF) of ovine origin. Biochemical and Biophysical Research Communications. 44: 205-10. PMID 4940370  1
1970 Fleischer N, Burgus R, Vale W, Dunn T, Guillemin R. Preliminary observations on the effect of synthetic thyrotropin releasing factor on plasma thyrotropin levels in man. The Journal of Clinical Endocrinology and Metabolism. 31: 109-12. PMID 4987499 DOI: 10.1210/jcem-31-1-109  1
1970 Burgus R, Dunn TF, Desiderio D, Ward DN, Vale W, Guillemin R. Characterization of ovine hypothalamic hypophysiotropic TSH-releasing factor. Nature. 226: 321-5. PMID 4985794  1
1970 Vale W, Burgus R, Dunn TF, Guillemin R. Release of TSH by oral administration of synthetic peptide derivatives with TRF activity. The Journal of Clinical Endocrinology and Metabolism. 30: 148-50. PMID 4984011 DOI: 10.1210/jcem-30-1-148  1
1970 Burgus R, Dunn TF, Desiderio DM, Ward DN, Vale W, Guillemin R, Felix AM, Gillessen D, Studer RO. Biological activity of synthetic polypeptide derivatives related to the structure of hypothalamic TRF. Endocrinology. 86: 573-82. PMID 4983136 DOI: 10.1210/endo-86-3-573  1
1970 Burgus R, Guillemin R. Hypothalamic releasing factors. Annual Review of Biochemistry. 39: 499-526. PMID 4320674 DOI: 10.1146/annurev.bi.39.070170.002435  0.88
1969 Burgus R, Dunn TF, Desiderio D, Guillemin R. [Molecular structure of the hypothalamic hypophysiotropic TRF factor of ovine origin: mass spectrometry demonstration of the PCA-His-Pro-NH2 sequence]. Comptes Rendus Hebdomadaires Des SéAnces De L'AcadéMie Des Sciences. SéRie D: Sciences Naturelles. 269: 1870-3. PMID 4983502  0.88
1969 Burgus R, Dunn TF, Desiderio D, Vale W, Guillemin R. [Synthetic polypeptide derivatives with TRF hypophysiotropic activity. New data]. Comptes Rendus Hebdomadaires Des SéAnces De L'AcadéMie Des Sciences. SéRie D: Sciences Naturelles. 269: 226-8. PMID 4981839  1
1969 Burgus R, Dunn TF, Ward DN, Vale W, Amoss M, Guillemin R. [Synthetic polypeptide derivatives with thyrotropin releasing factor hypophysiotropic activity]. Comptes Rendus Hebdomadaires Des SéAnces De L'AcadéMie Des Sciences. SéRie D: Sciences Naturelles. 268: 2116-8. PMID 4980352  1
1969 Rodger NW, Beck JC, Burgus R, Guillemin R. Variability of response in the bioassay for a hypothalamic somatotrophin releasing factor based on rat pituitary growth hormone content. Endocrinology. 84: 1373-83. PMID 4889113 DOI: 10.1210/endo-84-6-1373  0.88
1967 Vale W, Guillemin R. Potassium-induced stimulation of thyrotropin release in vitro. Requirement for presence of calcium and inhibition by thyroxine. Experientia. 23: 855-7. PMID 6076326  1
1967 Vale W, Burgus R, Guillemin R. Competition between thyroxine and TRF at the pituitary level in the release of TSH. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 125: 210-3. PMID 6028912  1
1967 Ducommun P, Vale W, Sakiz E, Guillemin R. Reversal of the inhibition of TSH secretion due to acute stress. Endocrinology. 80: 953-6. PMID 6023562 DOI: 10.1210/endo-80-5-953  1
1967 Vale W, Burgus R, Guillemin R. Presence of calcium ions as a requisite for the in vitro stimulation of TSH-release by hypothalamic TRF. Experientia. 23: 853-5. PMID 4965560  1
1967 Burgus R, Amoss MS, Guillemin R. Solubility of the hypothalamic hormones TSH-releasing factor (TRF) and LH-releasing factor (LRF) in organic and alcoholic solvents. Experientia. 23: 417-8. PMID 4965008  0.88
1964 SCHALLY AV, GUILLEMIN R. SOME BIOLOGICAL AND CHEMICAL PROPERTIES OF A LYSINE- VASOPRESSIN DIMER. The Journal of Biological Chemistry. 239: 1038-41. PMID 14165903  1
1963 GUILLEMIN R, SCHALLY AV. CONCENTRATION OF CORTICOTROPIN RELEASING FACTOR (CRF) IN ACID EXTRACTS OF SHEEP HYPOTHALAMUS BY GEL FILTRATION AND COUNTER CURRENT DISTRIBUTION. Texas Reports On Biology and Medicine. 21: 541-5. PMID 14087155  1
1963 SCHALLY AV, GUILLEMIN R. Isolation and chemical characterization of a beta-CRF from pig posterior pituitary glands. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 112: 1014-7. PMID 13976659  1
1962 SCHALLY AV, LIPSCOMB HS, LONG JM, DEAR WE, GUILLEMIN R. Chromatography and hormonal activities of dog hypothalamus. Endocrinology. 70: 478-80. PMID 14498007 DOI: 10.1210/endo-70-4-478  1
1962 SCHALLY AV, LIPSCOMB HS, GUILLEMIN R. Isolation and amino acid sequence of alpha2-corticotropin-releasing factor (alpha2-CRF) from hog pituitary glands. Endocrinology. 71: 164-73. PMID 14498006 DOI: 10.1210/endo-71-1-164  1
1962 SCHALLY AV, ROBINSON S, GUILLEMIN R. Quantitative aspects of percolation for the extraction of oxytocin and vasopressin. Texas Reports On Biology and Medicine. 20: 680-2. PMID 13976658  1
1962 GUILLEMIN R, SCHALLY AV, LIPSCOMB HS, ANDERSEN RN, LONG JM. On the presence in hog hypothalamus of 3-corticotropin releasing factor, alpha- and beta-melanocyte stimulating hormones, adrenocorticotropin, lysine-vasopressin and oxytocin. Endocrinology. 70: 471-7. PMID 13902822 DOI: 10.1210/endo-70-4-471  1
1961 GUILLEMIN R, SCHALLY AV. On the nature of the hypothalamic substance which controls the secretion of ACTH. Acta Neurovegetativa. 23: 58-62. PMID 13902823  1
1960 SCHALLY AV, GUILLEMIN R. Studies on corticotropin releasing factor: ion exchange chromotography of pituitary preparations. Texas Reports On Biology and Medicine. 18: 133-46. PMID 14442406  1
1960 SCHALLY AV, ANDERSEN RN, LONG JM, GUILLEMIN R. Isolation of alpha- and beta-melanocyte stimulating hormones (MSH) on a preparative scale. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 104: 290-3. PMID 14442404 DOI: 10.3181/00379727-104-25812  1
1960 SCHALLY AV, ANDERSEN RN, LIPSCOMB HS, LONG JM, GUILLEMIN R. Evidence for the existence of two corticotrophin-releasing factors, alpha and beta. Nature. 188: 192-3. PMID 13747238  1
1959 GUILLEMIN R, SCHALLY AV. Re-evaluation of a technique of pituitary incubation in vitro as an assay for corticotropin releasing factor. Endocrinology. 65: 555-62. PMID 13830170 DOI: 10.1210/endo-65-4-555  1
1959 SCHALLY AV, GUILLEMIN R. Concentration of corticotropin releasing factor by chromatography on carboxymethylcellulose. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 100: 138-9. PMID 13634063  1
1959 SCHALLY AV, LIPSCOMB HS, GUILLEMIN R. Chromatographic separation of oxytocin and vasopressin on carboxymethylcellulose. Biochimica Et Biophysica Acta. 31: 252-4. PMID 13628630  1
1953 HORAVA A, GUILLEMIN R, SELYE H. [Effect of Reichstein's compound L on certain effects from the administration of an anterior pituitary lobe extract]. Annales D'Endocrinologie. 14: 779-83. PMID 13138984  1
1952 SELYE H, GUILLEMIN R. [General adaptation syndrome]. Maroc MéDical. 31: 259-63. PMID 14947270  1
1952 GUILLEMIN R, SELYE H. [Nephrosclerotic and prophlogistic effect of various preparations of somatotropic hormones]. Annales D'Endocrinologie. 13: 836-40. PMID 13031204  1
1950 GUILLEMIN R, SELYE H. [Mineral-corticoid inhibition of renal inactivation of vasopressive substances]. Annales D'Endocrinologie. 11: 270-5. PMID 14811084  1
1950 GUILLEMIN R, SELYE H. [Action of mineral-corticoids on the behavior of the kidney towards vasopresor substances of angiotonin type]. Revue Canadienne De Biologie / éDitéE Par L'Université De MontréAl. 9: 309. PMID 14776349  1
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