J K. Sethi - Publications

Clinical Biochemistry University of Cambridge, Cambridge, England, United Kingdom 

49 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Grolla AA, Travelli C, Genazzani AA, Sethi JK. Extracellular Nicotinamide Phosphoribosyltrasferase (eNAMPT), A New Cancer Metabokine. British Journal of Pharmacology. PMID 27128025 DOI: 10.1111/Bph.13505  0.4
2015 Patel MN, Bernard WG, Milev NB, Cawthorn WP, Figg N, Hart D, Prieur X, Virtue S, Hegyi K, Bonnafous S, Bailly-Maitre B, Chu Y, Griffin JL, Mallat Z, Considine RV, ... ... Sethi JK, et al. Hematopoietic IKBKE limits the chronicity of inflammasome priming and metaflammation. Proceedings of the National Academy of Sciences of the United States of America. 112: 506-11. PMID 25540417 DOI: 10.7490/F1000Research.1110639.1  0.4
2014 Robinson KA, Hegyi K, Hannun YA, Buse MG, Sethi JK. Go-6976 reverses hyperglycemia-induced insulin resistance independently of cPKC inhibition in adipocytes. Plos One. 9: e108963. PMID 25330241 DOI: 10.1371/Journal.Pone.0108963  0.4
2013 Carobbio S, Hagen RM, Lelliott CJ, Slawik M, Medina-Gomez G, Tan CY, Sicard A, Atherton HJ, Barbarroja N, Bjursell M, Bohlooly-Y M, Virtue S, Tuthill A, Lefai E, Laville M, ... ... Sethi JK, et al. Adaptive changes of the Insig1/SREBP1/SCD1 set point help adipose tissue to cope with increased storage demands of obesity. Diabetes. 62: 3697-708. PMID 23919961 DOI: 10.2337/Db12-1748  0.4
2012 Hu CZ, Sethi JK, Hagen T. The role of the cullin-5 e3 ubiquitin ligase in the regulation of insulin receptor substrate-1. Biochemistry Research International. 2012: 282648. PMID 23304509 DOI: 10.1155/2012/282648  0.4
2012 Virtue S, Feldmann H, Christian M, Tan CY, Masoodi M, Dale M, Lelliott C, Burling K, Campbell M, Eguchi N, Voshol P, Sethi JK, Parker M, Urade Y, Griffin JL, et al. A new role for lipocalin prostaglandin d synthase in the regulation of brown adipose tissue substrate utilization. Diabetes. 61: 3139-47. PMID 22923471 DOI: 10.2337/Db12-0015  0.4
2012 Virtue S, Masoodi M, Velagapudi V, Tan CY, Dale M, Suorti T, Slawik M, Blount M, Burling K, Campbell M, Eguchi N, Medina-Gomez G, Sethi JK, OreÅ¡ič M, Urade Y, et al. Lipocalin prostaglandin D synthase and PPARγ2 coordinate to regulate carbohydrate and lipid metabolism in vivo. Plos One. 7: e39512. PMID 22792179 DOI: 10.1371/Journal.Pone.0039512  0.4
2012 Rajwani A, Ezzat V, Smith J, Yuldasheva NY, Duncan ER, Gage M, Cubbon RM, Kahn MB, Imrie H, Abbas A, Viswambharan H, Aziz A, Sukumar P, Vidal-Puig A, Sethi JK, et al. Increasing circulating IGFBP1 levels improves insulin sensitivity, promotes nitric oxide production, lowers blood pressure, and protects against atherosclerosis. Diabetes. 61: 915-24. PMID 22357965 DOI: 10.2337/Db11-0963  0.4
2011 Prieur X, Mok CY, Velagapudi VR, Núñez V, Fuentes L, Montaner D, Ishikawa K, Camacho A, Barbarroja N, O'Rahilly S, Sethi JK, Dopazo J, OreÅ¡ič M, Ricote M, Vidal-Puig A. Differential lipid partitioning between adipocytes and tissue macrophages modulates macrophage lipotoxicity and M2/M1 polarization in obese mice. Diabetes. 60: 797-809. PMID 21266330 DOI: 10.2337/Db10-0705  0.4
2011 Sethi JK, Vidal-Puig AJ. Adipose tissue development, structure and function Metabolic Basis of Obesity. 53-68. DOI: 10.1007/978-1-4419-1607-5_3  0.4
2010 Sethi JK. Activatin' human adipose progenitors in obesity. Diabetes. 59: 2354-7. PMID 20876727 DOI: 10.2337/Db10-0923  0.4
2010 Virtue S, Dale M, Sethi JK, Vidal-Puig A. LEM-PCR: a method for determining relative transcript isoform proportions using real-time PCR without a standard curve. Genome / National Research Council Canada = Gã©Nome / Conseil National De Recherches Canada. 53: 637-42. PMID 20725151 DOI: 10.1139/G10-036  0.4
2010 Lagathu C, Christodoulides C, Tan CY, Virtue S, Laudes M, Campbell M, Ishikawa K, Ortega F, Tinahones FJ, Fernández-Real JM, OreÅ¡ič M, Sethi JK, Vidal-Puig A. Secreted frizzled-related protein 1 regulates adipose tissue expansion and is dysregulated in severe obesity. International Journal of Obesity (2005). 34: 1695-705. PMID 20514047 DOI: 10.1038/Ijo.2010.107  0.4
2010 Sethi JK, Vidal-Puig A. Wnt signalling and the control of cellular metabolism. The Biochemical Journal. 427: 1-17. PMID 20226003 DOI: 10.1042/Bj20091866  0.4
2009 Morgan SA, Sherlock M, Gathercole LL, Lavery GG, Lenaghan C, Bujalska IJ, Laber D, Yu A, Convey G, Mayers R, Hegyi K, Sethi JK, Stewart PM, Smith DM, Tomlinson JW. 11beta-hydroxysteroid dehydrogenase type 1 regulates glucocorticoid-induced insulin resistance in skeletal muscle. Diabetes. 58: 2506-15. PMID 19675138 DOI: 10.2337/Db09-0525  0.4
2009 Lagathu C, Christodoulides C, Virtue S, Cawthorn WP, Franzin C, Kimber WA, Nora ED, Campbell M, Medina-Gomez G, Cheyette BN, Vidal-Puig AJ, Sethi JK. Dact1, a nutritionally regulated preadipocyte gene, controls adipogenesis by coordinating the Wnt/beta-catenin signaling network. Diabetes. 58: 609-19. PMID 19073771 DOI: 10.2337/Db08-1180  0.4
2009 Christodoulides C, Lagathu C, Sethi JK, Vidal-Puig A. Adipogenesis and WNT signalling. Trends in Endocrinology and Metabolism: Tem. 20: 16-24. PMID 19008118 DOI: 10.1016/J.Tem.2008.09.002  0.4
2008 Sethi JK, Vidal-Puig AJ. Wnt signalling at the crossroads of nutritional regulation. The Biochemical Journal. 416: e11-3. PMID 18990086 DOI: 10.1042/Bj20082074  0.4
2008 Lim JC, Kania KD, Wijesuriya H, Chawla S, Sethi JK, Pulaski L, Romero IA, Couraud PO, Weksler BB, Hladky SB, Barrand MA. Activation of beta-catenin signalling by GSK-3 inhibition increases p-glycoprotein expression in brain endothelial cells. Journal of Neurochemistry. 106: 1855-65. PMID 18624906 DOI: 10.1111/J.1471-4159.2008.05537.X  0.4
2008 Cawthorn WP, Sethi JK. TNF-alpha and adipocyte biology. Febs Letters. 582: 117-31. PMID 18037376 DOI: 10.1016/J.Febslet.2007.11.051  0.4
2007 Sethi JK, Vidal-Puig AJ. Targeting fat to prevent diabetes. Cell Metabolism. 5: 323-5. PMID 17488634 DOI: 10.1016/J.Cmet.2007.04.006  0.4
2007 Cawthorn WP, Heyd F, Hegyi K, Sethi JK. Tumour necrosis factor-alpha inhibits adipogenesis via a beta-catenin/TCF4(TCF7L2)-dependent pathway. Cell Death and Differentiation. 14: 1361-73. PMID 17464333 DOI: 10.1038/Sj.Cdd.4402127  0.4
2007 Sethi JK, Vidal-Puig AJ. Thematic review series: adipocyte biology. Adipose tissue function and plasticity orchestrate nutritional adaptation. Journal of Lipid Research. 48: 1253-62. PMID 17374880 DOI: 10.1194/Jlr.R700005-Jlr200  0.4
2007 Sethi JK. Is PBEF/visfatin/Nampt an authentic adipokine relevant to the metabolic syndrome? Current Hypertension Reports. 9: 33-8. PMID 17362669 DOI: 10.1007/S11906-007-0007-5  0.4
2007 Aerts JM, Ottenhoff R, Powlson AS, Grefhorst A, van Eijk M, Dubbelhuis PF, Aten J, Kuipers F, Serlie MJ, Wennekes T, Sethi JK, O'Rahilly S, Overkleeft HS. Pharmacological inhibition of glucosylceramide synthase enhances insulin sensitivity. Diabetes. 56: 1341-9. PMID 17287460 DOI: 10.2337/Db06-1619  0.4
2007 Wheatcroft SB, Kearney MT, Shah AM, Ezzat VA, Miell JR, Modo M, Williams SC, Cawthorn WP, Medina-Gomez G, Vidal-Puig A, Sethi JK, Crossey PA. IGF-binding protein-2 protects against the development of obesity and insulin resistance. Diabetes. 56: 285-94. PMID 17259371 DOI: 10.2337/Db06-0436  0.4
2006 Christodoulides C, Laudes M, Cawthorn WP, Schinner S, Soos M, O'Rahilly S, Sethi JK, Vidal-Puig A. The Wnt antagonist Dickkopf-1 and its receptors are coordinately regulated during early human adipogenesis. Journal of Cell Science. 119: 2613-20. PMID 16763196 DOI: 10.1242/Jcs.02975  0.4
2006 Nawaratne R, Gray A, Jørgensen CH, Downes CP, Siddle K, Sethi JK. Regulation of insulin receptor substrate 1 pleckstrin homology domain by protein kinase C: role of serine 24 phosphorylation. Molecular Endocrinology (Baltimore, Md.). 20: 1838-52. PMID 16574739 DOI: 10.1210/Me.2005-0536  0.4
2006 Christodoulides C, Scarda A, Granzotto M, Milan G, Dalla Nora E, Keogh J, De Pergola G, Stirling H, Pannacciulli N, Sethi JK, Federspil G, Vidal-Puig A, Farooqi IS, O'Rahilly S, Vettor R. WNT10B mutations in human obesity. Diabetologia. 49: 678-84. PMID 16477437 DOI: 10.1007/S00125-006-0144-4  0.4
2005 Sethi JK, Vidal-Puig A. Visfatin: the missing link between intra-abdominal obesity and diabetes? Trends in Molecular Medicine. 11: 344-7. PMID 16005682 DOI: 10.1016/J.Molmed.2005.06.010  0.4
2005 Medina-Gomez G, Virtue S, Lelliott C, Boiani R, Campbell M, Christodoulides C, Perrin C, Jimenez-Linan M, Blount M, Dixon J, Zahn D, Thresher RR, Aparicio S, Carlton M, Colledge WH, ... ... Sethi JK, et al. The link between nutritional status and insulin sensitivity is dependent on the adipocyte-specific peroxisome proliferator-activated receptor-gamma2 isoform. Diabetes. 54: 1706-16. PMID 15919792 DOI: 10.2337/Diabetes.54.6.1706  0.4
2005 Jitrapakdee S, Slawik M, Medina-Gomez G, Campbell M, Wallace JC, Sethi JK, O'rahilly S, Vidal-Puig AJ. The peroxisome proliferator-activated receptor-gamma regulates murine pyruvate carboxylase gene expression in vivo and in vitro. The Journal of Biological Chemistry. 280: 27466-76. PMID 15917242 DOI: 10.1074/Jbc.M503836200  0.4
2004 Rochford JJ, Semple RK, Laudes M, Boyle KB, Christodoulides C, Mulligan C, Lelliott CJ, Schinner S, Hadaschik D, Mahadevan M, Sethi JK, Vidal-Puig A, O'Rahilly S. ETO/MTG8 is an inhibitor of C/EBPbeta activity and a regulator of early adipogenesis. Molecular and Cellular Biology. 24: 9863-72. PMID 15509789 DOI: 10.1128/Mcb.24.22.9863-9872.2004  0.4
2004 Sethi JK. A burst of energy in metabolic disease research. Genome Biology. 5: 327. PMID 15186487 DOI: 10.1186/Gb-2004-5-6-327  0.4
2004 Hagen T, Sethi JK, Foxwell N, Vidal-Puig A. Signalling activity of beta-catenin targeted to different subcellular compartments. The Biochemical Journal. 379: 471-7. PMID 14733614 DOI: 10.1042/Bj20031749  0.4
2004 Laudes M, Christodoulides C, Sewter C, Rochford JJ, Considine RV, Sethi JK, Vidal-Puig A, O'Rahilly S. Role of the POZ zinc finger transcription factor FBI-1 in human and murine adipogenesis. The Journal of Biological Chemistry. 279: 11711-8. PMID 14701838 DOI: 10.1074/Jbc.M310240200  0.4
2003 Meirhaeghe A, Crowley V, Lenaghan C, Lelliott C, Green K, Stewart A, Hart K, Schinner S, Sethi JK, Yeo G, Brand MD, Cortright RN, O'Rahilly S, Montague C, Vidal-Puig AJ. Characterization of the human, mouse and rat PGC1 beta (peroxisome-proliferator-activated receptor-gamma co-activator 1 beta) gene in vitro and in vivo. The Biochemical Journal. 373: 155-65. PMID 12678921 DOI: 10.1042/Bj20030200  0.4
2001 Mohamed-Ali V, Flower L, Sethi J, Hotamisligil G, Gray R, Humphries SE, York DA, Pinkney J. β-adrenergic regulation of IL-6 release from adipose tissue: In vivo and in vitro studies Journal of Clinical Endocrinology and Metabolism. 86: 5864-5869. PMID 11739453 DOI: 10.1210/Jcem.86.12.8104  0.4
2000 Sethi JK, Xu H, Uysal KT, Wiesbrock SM, Scheja L, Hotamisligil GS. Characterisation of receptor-specific TNFalpha functions in adipocyte cell lines lacking type 1 and 2 TNF receptors. Febs Letters. 469: 77-82. PMID 10708760 DOI: 10.1016/S0014-5793(00)01250-3  0.4
1999 Xu H, Sethi JK, Hotamisligil GS. Transmembrane tumor necrosis factor (TNF)-alpha inhibits adipocyte differentiation by selectively activating TNF receptor 1. The Journal of Biological Chemistry. 274: 26287-95. PMID 10473584 DOI: 10.1074/Jbc.274.37.26287  0.4
1999 Sethi JK, Hotamisligil GS. The role of TNF alpha in adipocyte metabolism. Seminars in Cell & Developmental Biology. 10: 19-29. PMID 10355025 DOI: 10.1006/Scdb.1998.0273  0.4
1997 Ashamu GA, Sethi JK, Galione A, Potter BV. Roles for adenosine ribose hydroxyl groups in cyclic adenosine 5'-diphosphate ribose-mediated Ca2+ release. Biochemistry. 36: 9509-17. PMID 9235996 DOI: 10.1021/Bi9705671  0.4
1997 Sethi JK, Empson RM, Bailey VC, Potter BV, Galione A. 7-Deaza-8-bromo-cyclic ADP-ribose, the first membrane-permeant, hydrolysis-resistant cyclic ADP-ribose antagonist. The Journal of Biological Chemistry. 272: 16358-63. PMID 9195942 DOI: 10.1074/Jbc.272.26.16358  0.4
1997 Bailey VC, Sethi JK, Fortt SM, Galione A, Potter BV. 7-Deaza cyclic adenosine 5'-diphosphate ribose: first example of a Ca(2+)-mobilizing partial agonist related to cyclic adenosine 5'-diphosphate ribose. Chemistry & Biology. 4: 51-61. PMID 9070427 DOI: 10.1016/S1074-5521(97)90236-2  0.4
1997 Bailey VC, Sethi JK, Galione A, Potter BVL. Synthesis of 7-deaza-8-bromo cyclic adenosine 5′-diphosphate ribose: The first hydrolysis resistant antagonist at the cADPR receptor Chemical Communications. 695-696. DOI: 10.1039/A700336F  0.4
1996 Sethi JK, Empson RM, Galione A. Nicotinamide inhibits cyclic ADP-ribose-mediated calcium signalling in sea urchin eggs. The Biochemical Journal. 319: 613-7. PMID 8912702 DOI: 10.1042/Bj3190613  0.4
1996 Willmott N, Sethi JK, Walseth TF, Lee HC, White AM, Galione A. Nitric oxide-induced mobilization of intracellular calcium via the cyclic ADP-ribose signaling pathway. The Journal of Biological Chemistry. 271: 3699-705. PMID 8631983 DOI: 10.1074/Jbc.271.7.3699  0.4
1992 McDanell RE, Beales D, Henderson L, Sethi JK. Effect of dietary fat on the in vitro hepatotoxicity of paracetamol. Biochemical Pharmacology. 44: 1303-6. PMID 1417954 DOI: 10.1016/0006-2952(92)90530-V  0.4
1991 Nazareth WM, Sethi JK, McLean AE. Effect of paracetamol on mitochondrial membrane function in rat liver slices. Biochemical Pharmacology. 42: 931-6. PMID 1867647 DOI: 10.1016/0006-2952(91)90055-A  0.4
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