Year |
Citation |
Score |
2023 |
Blair RE, Hawkins E, Pinchbeck LR, DeLorenzo RJ, Deshpande LS. . The Journal of Pharmacology and Experimental Therapeutics. PMID 37643794 DOI: 10.1124/jpet.123.001739 |
0.819 |
|
2021 |
Kirmani BF, Au K, Ayari L, John M, Shetty P, Delorenzo RJ. Super-Refractory Status Epilepticus: Prognosis and Recent Advances in Management. Aging and Disease. 12: 1097-1119. PMID 34221552 DOI: 10.14336/AD.2021.0302 |
0.306 |
|
2020 |
Deshpande LS, Blair RE, Halquist M, Kosmider L, DeLorenzo RJ. Intramuscular atenolol and levetiracetam reduce mortality in a rat model of paraoxon-induced status epilepticus. Annals of the New York Academy of Sciences. PMID 32961584 DOI: 10.1111/nyas.14500 |
0.767 |
|
2020 |
Deshpande LS, DeLorenzo RJ, Churn SB, Parsons JT. Neuronal-Specific Inhibition of Endoplasmic Reticulum Mg/Ca ATPase Ca Uptake in a Mixed Primary Hippocampal Culture Model of Status Epilepticus. Brain Sciences. 10. PMID 32664397 DOI: 10.3390/Brainsci10070438 |
0.834 |
|
2019 |
Deshpande LS, DeLorenzo RJ. Novel therapeutics for treating organophosphate-induced status epilepticus co-morbidities, based on changes in calcium homeostasis. Neurobiology of Disease. PMID 30872159 DOI: 10.1016/J.Nbd.2019.03.006 |
0.839 |
|
2018 |
Phillips KF, Deshpande LS, DeLorenzo RJ. Hypothermia Reduces Mortality, Prevents the Calcium Plateau, and Is Neuroprotective Following Status Epilepticus in Rats. Frontiers in Neurology. 9: 438. PMID 29942282 DOI: 10.3389/Fneur.2018.00438 |
0.829 |
|
2016 |
Deshpande LS, Blair RE, Phillips KF, DeLorenzo RJ. Role of the calcium plateau in neuronal injury and behavioral morbidities following organophosphate intoxication. Annals of the New York Academy of Sciences. PMID 27327161 DOI: 10.1111/Nyas.13122 |
0.803 |
|
2016 |
Deshpande LS, Blair RE, Huang BA, Phillips KF, DeLorenzo RJ. Pharmacological blockade of the calcium plateau provides neuroprotection following organophosphate paraoxon induced status epilepticus in rats. Neurotoxicology and Teratology. PMID 27224207 DOI: 10.1016/J.Ntt.2016.05.002 |
0.824 |
|
2015 |
Blair RE, Deshpande LS, DeLorenzo RJ. Cannabinoids: is there a potential treatment role in epilepsy? Expert Opinion On Pharmacotherapy. 16: 1911-4. PMID 26234319 DOI: 10.1517/14656566.2015.1074181 |
0.802 |
|
2015 |
Blair RE, Deshpande LS, DeLorenzo RJ. Endocannabinoids and epilepsy Cannabinoids in Neurologic and Mental Disease. 125-172. DOI: 10.1016/B978-0-12-417041-4.00006-0 |
0.788 |
|
2014 |
Deshpande LS, Phillips K, Huang B, DeLorenzo RJ. Chronic behavioral and cognitive deficits in a rat survival model of paraoxon toxicity. Neurotoxicology. 44: 352-7. PMID 25172410 DOI: 10.1016/J.Neuro.2014.08.008 |
0.767 |
|
2014 |
Deshpande LS, Carter DS, Phillips KF, Blair RE, DeLorenzo RJ. Development of status epilepticus, sustained calcium elevations and neuronal injury in a rat survival model of lethal paraoxon intoxication. Neurotoxicology. 44: 17-26. PMID 24785379 DOI: 10.1016/J.Neuro.2014.04.006 |
0.833 |
|
2014 |
Deshpande LS, Delorenzo RJ. Mechanisms of levetiracetam in the control of status epilepticus and epilepsy. Frontiers in Neurology. 5: 11. PMID 24550884 DOI: 10.3389/Fneur.2014.00011 |
0.797 |
|
2013 |
Phillips KF, Deshpande LS, DeLorenzo RJ. Hypothermia reduces calcium entry via the N-methyl-D-aspartate and ryanodine receptors in cultured hippocampal neurons. European Journal of Pharmacology. 698: 186-92. PMID 23085028 DOI: 10.1016/J.Ejphar.2012.10.010 |
0.81 |
|
2012 |
Sayers KW, Nguyen PT, Blair RE, Sim-Selley LJ, DeLorenzo RJ. Statistical parametric mapping reveals regional alterations in cannabinoid CB1 receptor distribution and G-protein activation in the 3D reconstructed epileptic rat brain. Epilepsia. 53: 897-907. PMID 22509801 DOI: 10.1111/J.1528-1167.2012.03460.X |
0.394 |
|
2011 |
Deshpande LS, Blair RE, DeLorenzo RJ. Prolonged cannabinoid exposure alters GABA(A) receptor mediated synaptic function in cultured hippocampal neurons. Experimental Neurology. 229: 264-73. PMID 21324315 DOI: 10.1016/J.Expneurol.2011.02.007 |
0.808 |
|
2011 |
Carter DS, Deshpande LS, Rafiq A, Sombati S, DeLorenzo RJ. Characterization of spontaneous recurrent epileptiform discharges in hippocampal-entorhinal cortical slices prepared from chronic epileptic animals. Seizure. 20: 218-24. PMID 21168348 DOI: 10.1016/J.Seizure.2010.11.022 |
0.841 |
|
2011 |
Ziobro JM, Deshpande LS, Delorenzo RJ. An organotypic hippocampal slice culture model of excitotoxic injury induced spontaneous recurrent epileptiform discharges. Brain Research. 1371: 110-20. PMID 21111720 DOI: 10.1016/J.Brainres.2010.11.065 |
0.83 |
|
2011 |
Deshpande LS, DeLorenzo RJ. Acetaminophen inhibits status epilepticus in cultured hippocampal neurons. Neuroreport. 22: 15-8. PMID 21037491 DOI: 10.1097/Wnr.0B013E3283413231 |
0.837 |
|
2010 |
Nagarkatti N, Deshpande LS, Carter DS, DeLorenzo RJ. Dantrolene inhibits the calcium plateau and prevents the development of spontaneous recurrent epileptiform discharges following in vitro status epilepticus. The European Journal of Neuroscience. 32: 80-8. PMID 20597971 DOI: 10.1111/J.1460-9568.2010.07262.X |
0.854 |
|
2010 |
Deshpande LS, Carter DS, Blair RE, DeLorenzo RJ. Development of a prolonged calcium plateau in hippocampal neurons in rats surviving status epilepticus induced by the organophosphate diisopropylfluorophosphate. Toxicological Sciences : An Official Journal of the Society of Toxicology. 116: 623-31. PMID 20498005 DOI: 10.1093/Toxsci/Kfq157 |
0.834 |
|
2009 |
Blair RE, Deshpande LS, Sombati S, Elphick MR, Martin BR, DeLorenzo RJ. Prolonged exposure to WIN55,212-2 causes downregulation of the CB1 receptor and the development of tolerance to its anticonvulsant effects in the hippocampal neuronal culture model of acquired epilepsy. Neuropharmacology. 57: 208-18. PMID 19540252 DOI: 10.1016/J.Neuropharm.2009.06.007 |
0.843 |
|
2009 |
Nagarkatti N, Deshpande LS, DeLorenzo RJ. Development of the calcium plateau following status epilepticus: role of calcium in epileptogenesis. Expert Review of Neurotherapeutics. 9: 813-24. PMID 19496685 DOI: 10.1586/Ern.09.21 |
0.847 |
|
2009 |
Blair RE, Deshpande LS, Holbert WH, Churn SB, DeLorenzo RJ. Age-dependent mortality in the pilocarpine model of status epilepticus. Neuroscience Letters. 453: 233-7. PMID 19429042 DOI: 10.1016/J.Neulet.2009.02.035 |
0.781 |
|
2009 |
Falenski KW, Carter DS, Harrison AJ, Martin BR, Blair RE, DeLorenzo RJ. Temporal characterization of changes in hippocampal cannabinoid CB(1) receptor expression following pilocarpine-induced status epilepticus. Brain Research. 1262: 64-72. PMID 19368833 DOI: 10.1016/J.Brainres.2009.01.036 |
0.821 |
|
2009 |
DeLorenzo RJ, Kirmani B, Deshpande LS, Jakkampudi V, Towne AR, Waterhouse E, Garnett L, Ramakrishnan V. Comparisons of the mortality and clinical presentations of status epilepticus in private practice community and university hospital settings in Richmond, Virginia. Seizure. 18: 405-11. PMID 19324574 DOI: 10.1016/J.Seizure.2009.02.005 |
0.758 |
|
2008 |
Deshpande LS, Sun DA, Sombati S, Baranova A, Wilson MS, Attkisson E, Hamm RJ, DeLorenzo RJ. Alterations in neuronal calcium levels are associated with cognitive deficits after traumatic brain injury. Neuroscience Letters. 441: 115-9. PMID 18583041 DOI: 10.1016/J.Neulet.2008.05.113 |
0.825 |
|
2008 |
Blair RE, Sombati S, Churn SB, Delorenzo RJ. Epileptogenesis causes an N-methyl-d-aspartate receptor/Ca2+-dependent decrease in Ca2+/calmodulin-dependent protein kinase II activity in a hippocampal neuronal culture model of spontaneous recurrent epileptiform discharges. European Journal of Pharmacology. 588: 64-71. PMID 18495112 DOI: 10.1016/J.Ejphar.2008.04.021 |
0.433 |
|
2008 |
Deshpande LS, Nagarkatti N, Ziobro JM, Sombati S, DeLorenzo RJ. Carisbamate prevents the development and expression of spontaneous recurrent epileptiform discharges and is neuroprotective in cultured hippocampal neurons. Epilepsia. 49: 1795-802. PMID 18494784 DOI: 10.1111/J.1528-1167.2008.01667.X |
0.829 |
|
2008 |
Nagarkatti N, Deshpande LS, DeLorenzo RJ. Levetiracetam inhibits both ryanodine and IP3 receptor activated calcium induced calcium release in hippocampal neurons in culture. Neuroscience Letters. 436: 289-93. PMID 18406528 DOI: 10.1016/J.Neulet.2008.02.076 |
0.853 |
|
2008 |
Carter DS, Harrison AJ, Falenski KW, Blair RE, DeLorenzo RJ. Long-term decrease in calbindin-D28K expression in the hippocampus of epileptic rats following pilocarpine-induced status epilepticus. Epilepsy Research. 79: 213-23. PMID 18394865 DOI: 10.1016/J.Eplepsyres.2008.02.006 |
0.846 |
|
2008 |
Sun DA, Deshpande LS, Sombati S, Baranova A, Wilson MS, Hamm RJ, DeLorenzo RJ. Traumatic brain injury causes a long-lasting calcium (Ca2+)-plateau of elevated intracellular Ca levels and altered Ca2+ homeostatic mechanisms in hippocampal neurons surviving brain injury. The European Journal of Neuroscience. 27: 1659-72. PMID 18371074 DOI: 10.1111/J.1460-9568.2008.06156.X |
0.827 |
|
2008 |
Deshpande LS, Nagarkatti N, Sombati S, DeLorenzo RJ. The novel antiepileptic drug carisbamate (RWJ 333369) is effective in inhibiting spontaneous recurrent seizure discharges and blocking sustained repetitive firing in cultured hippocampal neurons. Epilepsy Research. 79: 158-65. PMID 18353614 DOI: 10.1016/J.Eplepsyres.2008.01.002 |
0.832 |
|
2008 |
Deshpande LS, Lou JK, Mian A, Blair RE, Sombati S, Attkisson E, DeLorenzo RJ. Time course and mechanism of hippocampal neuronal death in an in vitro model of status epilepticus: role of NMDA receptor activation and NMDA dependent calcium entry. European Journal of Pharmacology. 583: 73-83. PMID 18289526 DOI: 10.1016/J.Ejphar.2008.01.025 |
0.853 |
|
2007 |
Deshpande LS, Lou JK, Mian A, Blair RE, Sombati S, DeLorenzo RJ. In vitro status epilepticus but not spontaneous recurrent seizures cause cell death in cultured hippocampal neurons. Epilepsy Research. 75: 171-9. PMID 17624736 DOI: 10.1016/J.Eplepsyres.2007.05.011 |
0.841 |
|
2007 |
Deshpande LS, Limbrick DD, Sombati S, DeLorenzo RJ. Activation of a novel injury-induced calcium-permeable channel that plays a key role in causing extended neuronal depolarization and initiating neuronal death in excitotoxic neuronal injury. The Journal of Pharmacology and Experimental Therapeutics. 322: 443-52. PMID 17483292 DOI: 10.1124/Jpet.107.123182 |
0.824 |
|
2007 |
DeLorenzo RJ, Sun DA, Blair RE, Sombati S. An in vitro model of stroke-induced epilepsy: elucidation of the roles of glutamate and calcium in the induction and maintenance of stroke-induced epileptogenesis. International Review of Neurobiology. 81: 59-84. PMID 17433918 DOI: 10.1016/S0074-7742(06)81005-6 |
0.762 |
|
2007 |
Falenski KW, Blair RE, Sim-Selley LJ, Martin BR, DeLorenzo RJ. Status epilepticus causes a long-lasting redistribution of hippocampal cannabinoid type 1 receptor expression and function in the rat pilocarpine model of acquired epilepsy. Neuroscience. 146: 1232-44. PMID 17433556 DOI: 10.1016/J.Neuroscience.2007.01.065 |
0.822 |
|
2007 |
Raza M, Deshpande LS, Blair RE, Carter DS, Sombati S, DeLorenzo RJ. Aging is associated with elevated intracellular calcium levels and altered calcium homeostatic mechanisms in hippocampal neurons. Neuroscience Letters. 418: 77-81. PMID 17374449 DOI: 10.1016/J.Neulet.2007.03.005 |
0.828 |
|
2007 |
Deshpande LS, Blair RE, Nagarkatti N, Sombati S, Martin BR, DeLorenzo RJ. Development of pharmacoresistance to benzodiazepines but not cannabinoids in the hippocampal neuronal culture model of status epilepticus. Experimental Neurology. 204: 705-13. PMID 17289026 DOI: 10.1016/J.Expneurol.2007.01.001 |
0.833 |
|
2007 |
Deshpande LS, Blair RE, Ziobro JM, Sombati S, Martin BR, DeLorenzo RJ. Endocannabinoids block status epilepticus in cultured hippocampal neurons. European Journal of Pharmacology. 558: 52-9. PMID 17174949 DOI: 10.1016/J.Ejphar.2006.11.030 |
0.839 |
|
2007 |
Deshpande LS, Sombati S, Blair RE, Carter DS, Martin BR, DeLorenzo RJ. Cannabinoid CB1 receptor antagonists cause status epilepticus-like activity in the hippocampal neuronal culture model of acquired epilepsy. Neuroscience Letters. 411: 11-6. PMID 17110038 DOI: 10.1016/J.Neulet.2006.09.046 |
0.844 |
|
2006 |
Carter DS, Haider SN, Blair RE, Deshpande LS, Sombati S, DeLorenzo RJ. Altered calcium/calmodulin kinase II activity changes calcium homeostasis that underlies epileptiform activity in hippocampal neurons in culture. The Journal of Pharmacology and Experimental Therapeutics. 319: 1021-31. PMID 16971505 DOI: 10.1124/Jpet.106.110403 |
0.834 |
|
2006 |
DeLorenzo RJ, Sun DA, Deshpande LS. Erratum to "Cellular mechanisms underlying acquired epilepsy: the calcium hypothesis of the induction and maintenance of epilepsy." [Pharmacol. Ther. 105(3) (2005) 229-266]. Pharmacology & Therapeutics. 111: 288-325. PMID 16832874 DOI: 10.1016/J.Pharmthera.2004.10.015 |
0.842 |
|
2006 |
Blair RE, Deshpande LS, Sombati S, Falenski KW, Martin BR, DeLorenzo RJ. Activation of the cannabinoid type-1 receptor mediates the anticonvulsant properties of cannabinoids in the hippocampal neuronal culture models of acquired epilepsy and status epilepticus. The Journal of Pharmacology and Experimental Therapeutics. 317: 1072-8. PMID 16469864 DOI: 10.1124/Jpet.105.100354 |
0.826 |
|
2006 |
Leppik IE, Kelly KM, deToledo-Morrell L, Patrylo PR, DeLorenzo RJ, Mathern GW, White HS. Basic research in epilepsy and aging. Epilepsy Research. 68: S21-37. PMID 16384687 DOI: 10.1016/J.Eplepsyres.2005.07.014 |
0.441 |
|
2006 |
DeLorenzo RJ, Sun DA. Basic mechanisms in status epilepticus: role of calcium in neuronal injury and the induction of epileptogenesis. Advances in Neurology. 97: 187-97. PMID 16383128 |
0.713 |
|
2005 |
Delorenzo RJ, Sun DA, Deshpande LS. Cellular mechanisms underlying acquired epilepsy: the calcium hypothesis of the induction and maintainance of epilepsy. Pharmacology & Therapeutics. 105: 229-66. PMID 15737406 DOI: 10.1016/J.Pharmthera.2004.10.004 |
0.847 |
|
2004 |
Raza M, Blair RE, Sombati S, Carter DS, Deshpande LS, DeLorenzo RJ. Evidence that injury-induced changes in hippocampal neuronal calcium dynamics during epileptogenesis cause acquired epilepsy. Proceedings of the National Academy of Sciences of the United States of America. 101: 17522-7. PMID 15583136 DOI: 10.1073/Pnas.0408155101 |
0.832 |
|
2004 |
Parsons JT, Sun DA, DeLorenzo RJ, Churn SB. Neuronal-specific endoplasmic reticulum Mg(2+)/Ca(2+) ATPase Ca(2+) sequestration in mixed primary hippocampal culture homogenates. Analytical Biochemistry. 330: 130-9. PMID 15183771 DOI: 10.1016/J.Ab.2004.03.025 |
0.71 |
|
2004 |
Blair RE, Sombati S, Lawrence DC, McCay BD, DeLorenzo RJ. Epileptogenesis causes acute and chronic increases in GABAA receptor endocytosis that contributes to the induction and maintenance of seizures in the hippocampal culture model of acquired epilepsy. The Journal of Pharmacology and Experimental Therapeutics. 310: 871-80. PMID 15084648 DOI: 10.1124/jpet.104.068478 |
0.358 |
|
2004 |
Sun DA, Sombati S, Blair RE, DeLorenzo RJ. Long-lasting alterations in neuronal calcium homeostasis in an in vitro model of stroke-induced epilepsy. Cell Calcium. 35: 155-63. PMID 14706289 DOI: 10.1016/J.Ceca.2003.09.003 |
0.758 |
|
2003 |
Wallace MJ, Blair RE, Falenski KW, Martin BR, DeLorenzo RJ. The endogenous cannabinoid system regulates seizure frequency and duration in a model of temporal lobe epilepsy. The Journal of Pharmacology and Experimental Therapeutics. 307: 129-37. PMID 12954810 DOI: 10.1124/Jpet.103.051920 |
0.814 |
|
2003 |
Rafiq A, Gong QZ, Lyeth BG, DeLorenzo RJ, Coulter DA. Induction of prolonged electrographic seizures in vitro has a defined threshold and is all or none: implications for diagnosis of status epilepticus. Epilepsia. 44: 1034-41. PMID 12887434 DOI: 10.1046/J.1528-1157.2003.51902.X |
0.347 |
|
2003 |
Limbrick DD, Sombati S, DeLorenzo RJ. Calcium influx constitutes the ionic basis for the maintenance of glutamate-induced extended neuronal depolarization associated with hippocampal neuronal death. Cell Calcium. 33: 69-81. PMID 12531183 DOI: 10.1016/S0143-4160(02)00054-4 |
0.636 |
|
2002 |
Sun DA, Sombati S, Blair RE, DeLorenzo RJ. Calcium-dependent epileptogenesis in an in vitro model of stroke-induced "epilepsy". Epilepsia. 43: 1296-305. PMID 12423378 DOI: 10.1046/J.1528-1157.2002.09702.X |
0.737 |
|
2002 |
Raza M, Shaheen F, Choudhary MI, Rahman AU, Sombati S, DeLorenzo RJ. In vitro inhibition of pentylenetetrazole and bicuculline-induced epileptiform activity in rat hippocampal pyramidal neurons by aqueous fraction isolated from Delphinium denudatum. Neuroscience Letters. 333: 103-6. PMID 12419491 DOI: 10.1016/S0304-3940(02)01027-3 |
0.353 |
|
2002 |
Wallace MJ, Martin BR, DeLorenzo RJ. Evidence for a physiological role of endocannabinoids in the modulation of seizure threshold and severity. European Journal of Pharmacology. 452: 295-301. PMID 12359270 DOI: 10.1016/S0014-2999(02)02331-2 |
0.791 |
|
2001 |
Wallace MJ, Wiley JL, Martin BR, DeLorenzo RJ. Assessment of the role of CB1 receptors in cannabinoid anticonvulsant effects. European Journal of Pharmacology. 428: 51-7. PMID 11779037 DOI: 10.1016/S0014-2999(01)01243-2 |
0.795 |
|
2001 |
Parsons JT, Churn SB, DeLorenzo RJ. Chronic inhibition of cortex microsomal Mg(2+)/Ca(2+) ATPase-mediated Ca(2+) uptake in the rat pilocarpine model following epileptogenesis. Journal of Neurochemistry. 79: 319-27. PMID 11677260 DOI: 10.1046/j.1471-4159.2001.00576.x |
0.364 |
|
2001 |
Sun DA, Sombati S, DeLorenzo RJ. Glutamate injury-induced epileptogenesis in hippocampal neurons: an in vitro model of stroke-induced "epilepsy". Stroke; a Journal of Cerebral Circulation. 32: 2344-50. PMID 11588324 |
0.402 |
|
2001 |
Pal S, Sun D, Limbrick D, Rafiq A, DeLorenzo RJ. Epileptogenesis induces long-term alterations in intracellular calcium release and sequestration mechanisms in the hippocampal neuronal culture model of epilepsy. Cell Calcium. 30: 285-96. PMID 11587552 DOI: 10.1054/Ceca.2001.0236 |
0.714 |
|
2001 |
Raza M, Shaheen F, Choudhary MI, Suria A, Rahman AU, Sombati S, DeLorenzo RJ. Anticonvulsant activities of the FS-1 subfraction isolated from roots of Delphinium denudatum. Phytotherapy Research : Ptr. 15: 426-30. PMID 11507736 DOI: 10.1002/ptr.792 |
0.313 |
|
2001 |
Kurz JE, Sheets D, Parsons JT, Rana A, Delorenzo RJ, Churn SB. A significant increase in both basal and maximal calcineurin activity in the rat pilocarpine model of status epilepticus. Journal of Neurochemistry. 78: 304-15. PMID 11461966 DOI: 10.1046/J.1471-4159.2001.00426.X |
0.355 |
|
2001 |
Raza M, Pal S, Rafiq A, DeLorenzo RJ. Long-term alteration of calcium homeostatic mechanisms in the pilocarpine model of temporal lobe epilepsy. Brain Research. 903: 1-12. PMID 11382382 DOI: 10.1016/S0006-8993(01)02127-8 |
0.469 |
|
2001 |
Limbrick DD, Pal S, DeLorenzo RJ. Hippocampal neurons exhibit both persistent Ca2+ influx and impairment of Ca2+ sequestration/extrusion mechanisms following excitotoxic glutamate exposure. Brain Research. 894: 56-67. PMID 11245815 DOI: 10.1016/S0006-8993(00)03303-5 |
0.586 |
|
2000 |
Pal S, Limbrick DD, Rafiq A, DeLorenzo RJ. Induction of spontaneous recurrent epileptiform discharges causes long-term changes in intracellular calcium homeostatic mechanisms. Cell Calcium. 28: 181-93. PMID 11020380 DOI: 10.1054/Ceca.2000.0146 |
0.646 |
|
2000 |
Parsons JT, Churn SB, Kochan LD, DeLorenzo RJ. Pilocarpine-induced status epilepticus causes N-methyl-D-aspartate receptor-dependent inhibition of microsomal Mg(2+)/Ca(2+) ATPase-mediated Ca(2+) uptake. Journal of Neurochemistry. 75: 1209-18. PMID 10936204 DOI: 10.1046/j.1471-4159.2000.0751209.x |
0.306 |
|
2000 |
Morris TA, Jafari N, DeLorenzo RJ. Chronic DeltaFosB expression and increased AP-1 transcription factor binding are associated with the long term plasticity changes in epilepsy. Brain Research. Molecular Brain Research. 79: 138-49. PMID 10925151 DOI: 10.1016/S0169-328X(00)00112-1 |
0.378 |
|
2000 |
Churn SB, Sombati S, Jakoi ER, Severt L, DeLorenzo RJ, Sievert L. Inhibition of calcium/calmodulin kinase II alpha subunit expression results in epileptiform activity in cultured hippocampal neurons. Proceedings of the National Academy of Sciences of the United States of America. 97: 5604-9. PMID 10779547 DOI: 10.1073/Pnas.080071697 |
0.766 |
|
2000 |
DeLorenzo RJ, Sombati S, Coulter DA. Effects of topiramate on sustained repetitive firing and spontaneous recurrent seizure discharges in cultured hippocampal neurons. Epilepsia. 41: S40-4. PMID 10768299 DOI: 10.1111/J.1528-1157.2000.Tb02170.X |
0.424 |
|
2000 |
Kochan LD, Churn SB, Omojokun O, Rice A, DeLorenzo RJ. Status epilepticus results in an N-methyl-D-aspartate receptor-dependent inhibition of Ca2+/calmodulin-dependent kinase II activity in the rat. Neuroscience. 95: 735-43. PMID 10670440 DOI: 10.1016/S0306-4522(99)00462-5 |
0.358 |
|
1999 |
Blair RE, Churn SB, Sombati S, Lou JK, DeLorenzo RJ. Long-lasting decrease in neuronal Ca2+/calmodulin-dependent protein kinase II activity in a hippocampal neuronal culture model of spontaneous recurrent seizures. Brain Research. 851: 54-65. PMID 10642828 DOI: 10.1016/S0006-8993(99)02100-9 |
0.342 |
|
1999 |
Pal S, Sombati S, Limbrick DD, DeLorenzo RJ. In vitro status epilepticus causes sustained elevation of intracellular calcium levels in hippocampal neurons. Brain Research. 851: 20-31. PMID 10642824 DOI: 10.1016/S0006-8993(99)02035-1 |
0.633 |
|
1999 |
Coulter DA, DeLorenzo RJ. Basic mechanisms of status epilepticus. Advances in Neurology. 79: 725-33. PMID 10514858 |
0.359 |
|
1999 |
Morris TA, Jafari N, Rice AC, Vasconcelos O, DeLorenzo RJ. Persistent increased DNA-binding and expression of serum response factor occur with epilepsy-associated long-term plasticity changes. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 8234-43. PMID 10493724 |
0.383 |
|
1999 |
Rice AC, DeLorenzo RJ. N-methyl-D-aspartate receptor activation regulates refractoriness of status epilepticus to diazepam. Neuroscience. 93: 117-23. PMID 10430476 DOI: 10.1016/S0306-4522(99)00132-3 |
0.355 |
|
1999 |
Delorenzo RJ, Morris TA. ■ REVIEW : Long-Term Modulation of Gene Expression in Epilepsy The Neuroscientist. 5: 86-99. DOI: 10.1177/107385849900500213 |
0.368 |
|
1998 |
DeLorenzo RJ, Pal S, Sombati S. Prolonged activation of the N-methyl-D-aspartate receptor-Ca2+ transduction pathway causes spontaneous recurrent epileptiform discharges in hippocampal neurons in culture. Proceedings of the National Academy of Sciences of the United States of America. 95: 14482-7. PMID 9826726 DOI: 10.1073/pnas.95.24.14482 |
0.442 |
|
1998 |
Rice AC, Floyd CL, Lyeth BG, Hamm RJ, DeLorenzo RJ. Status epilepticus causes long-term NMDA receptor-dependent behavioral changes and cognitive deficits. Epilepsia. 39: 1148-57. PMID 9821978 DOI: 10.1111/J.1528-1157.1998.Tb01305.X |
0.366 |
|
1998 |
Rice AC, DeLorenzo RJ. NMDA receptor activation during status epilepticus is required for the development of epilepsy. Brain Research. 782: 240-7. PMID 9519269 DOI: 10.1016/S0006-8993(97)01285-7 |
0.379 |
|
1998 |
Shapiro SM, Churn SB, Pal S, Limbrick D, DeLorenzo RJ. Bilirubin Alters Intracellular Calcium Homeostasis • 1135 Pediatric Research. 43: 195-195. DOI: 10.1203/00006450-199804001-01156 |
0.663 |
|
1997 |
Jaitly R, Sgro JA, Towne AR, Ko D, DeLorenzo RJ. Prognostic value of EEG monitoring after status epilepticus: a prospective adult study. Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society. 14: 326-34. PMID 9337142 DOI: 10.1097/00004691-199707000-00005 |
0.363 |
|
1997 |
Parsons JT, Churn SB, DeLorenzo RJ. Ischemia-induced inhibition of calcium uptake into rat brain microsomes mediated by Mg2+/Ca2+ ATPase. Journal of Neurochemistry. 68: 1124-34. PMID 9048758 |
0.3 |
|
1996 |
Coulter DA, Rafiq A, Shumate M, Gong QZ, DeLorenzo RJ, Lyeth BG. Brain injury-induced enhanced limbic epileptogenesis: anatomical and physiological parallels to an animal model of temporal lobe epilepsy. Epilepsy Research. 26: 81-91. PMID 8985690 DOI: 10.1016/S0920-1211(96)00044-7 |
0.468 |
|
1996 |
Vick RS, Rafiq A, Coulter DA, Jakoi ER, DeLorenzo RJ. GABAA alpha 2 mRNA levels are decreased following induction of spontaneous epileptiform discharges in hippocampal-entorhinal cortical slices. Brain Research. 721: 111-9. PMID 8793090 DOI: 10.1016/0006-8993(96)00060-1 |
0.755 |
|
1996 |
DeLorenzo RJ, Limbrick DD. Effects of glutamate on calcium influx and sequestration/extrusion mechanisms in hippocampal neurons. Advances in Neurology. 71: 37-46. PMID 8790787 |
0.365 |
|
1996 |
Rice A, Rafiq A, Shapiro SM, Jakoi ER, Coulter DA, DeLorenzo RJ. Long-lasting reduction of inhibitory function and gamma-aminobutyric acid type A receptor subunit mRNA expression in a model of temporal lobe epilepsy. Proceedings of the National Academy of Sciences of the United States of America. 93: 9665-9. PMID 8790388 DOI: 10.1073/Pnas.93.18.9665 |
0.771 |
|
1995 |
Jakoi ER, Panchision DM, Gerwin CM, DeLorenzo RJ. Post-transcriptional regulation of gene expression in hippocampal neurons by glutamate receptor activation. Brain Research. 693: 124-32. PMID 8653400 DOI: 10.1016/0006-8993(95)00599-L |
0.812 |
|
1995 |
Rafiq A, Zhang YF, DeLorenzo RJ, Coulter DA. Long-duration self-sustained epileptiform activity in the hippocampal-parahippocampal slice: a model of status epilepticus. Journal of Neurophysiology. 74: 2028-42. PMID 8592194 DOI: 10.1152/Jn.1995.74.5.2028 |
0.352 |
|
1995 |
Limbrick DD, Churn SB, Sombati S, DeLorenzo RJ. Inability to restore resting intracellular calcium levels as an early indicator of delayed neuronal cell death. Brain Research. 690: 145-56. PMID 8535831 DOI: 10.1016/0006-8993(95)00552-2 |
0.62 |
|
1995 |
Churn SB, Limbrick D, Sombati S, DeLorenzo RJ. Excitotoxic activation of the NMDA receptor results in inhibition of calcium/calmodulin kinase II activity in cultured hippocampal neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 15: 3200-14. PMID 7722657 |
0.322 |
|
1995 |
Sombati S, Delorenzo RJ. Recurrent spontaneous seizure activity in hippocampal neuronal networks in culture. Journal of Neurophysiology. 73: 1706-11. PMID 7643176 |
0.396 |
|
1995 |
Panchision DM, Gerwin CM, DeLorenzo RJ, Jakoi ER. Glutamate receptor activation regulates mRNA at both transcriptional and posttranscriptional levels. Journal of Neurochemistry. 65: 969-77. PMID 7643127 DOI: 10.1046/J.1471-4159.1995.65030969.X |
0.792 |
|
1995 |
Churn S, Limbrick D, Sombati S, DeLorenzo R. Excitotoxic activation of the NMDA receptor results in inhibition of calcium/calmodulin kinase II activity in cultured hippocampal neurons The Journal of Neuroscience. 15: 3200-3214. DOI: 10.1523/Jneurosci.15-04-03200.1995 |
0.575 |
|
1993 |
Perlin JB, Gerwin CM, Panchision DM, Vick RS, Jakoi ER, DeLorenzo RJ. Kindling produces long-lasting and selective changes in gene expression of hippocampal neurons. Proceedings of the National Academy of Sciences of the United States of America. 90: 1741-5. PMID 8446587 DOI: 10.1073/Pnas.90.5.1741 |
0.817 |
|
1993 |
Rafiq A, DeLorenzo RJ, Coulter DA. Generation and propagation of epileptiform discharges in a combined entorhinal cortex/hippocampal slice. Journal of Neurophysiology. 70: 1962-74. PMID 8294965 DOI: 10.1152/Jn.1993.70.5.1962 |
0.305 |
|
1993 |
Churn SB, Sombati S, Taft WC, DeLorenzo RJ. Excitotoxicity affects membrane potential and calmodulin kinase II activity in cultured rat cortical neurons. Stroke; a Journal of Cerebral Circulation. 24: 271-7; discussion 27. PMID 8093648 |
0.338 |
|
1992 |
Coulter DA, Sombati S, DeLorenzo RJ. Electrophysiology of glutamate neurotoxicity in vitro: induction of a calcium-dependent extended neuronal depolarization. Journal of Neurophysiology. 68: 362-73. PMID 1388200 DOI: 10.1152/Jn.1992.68.2.362 |
0.366 |
|
1992 |
Jakoi ER, Sombati S, Gerwin C, DeLorenzo RJ. Excitatory amino acid receptor activation produces a selective and long-lasting modulation of gene expression in hippocampal neurons. Brain Research. 582: 282-90. PMID 1382803 DOI: 10.1016/0006-8993(92)90145-Y |
0.769 |
|
1992 |
Perlin JB, Churn SB, Lothman EW, DeLorenzo RJ. Loss of type II calcium/calmodulin-dependent kinase activity correlates with stages of development of electrographic seizures in status epilepticus in rat. Epilepsy Research. 11: 111-8. PMID 1319899 DOI: 10.1016/0920-1211(92)90045-U |
0.307 |
|
1991 |
Sombati S, Coulter DA, DeLorenzo RJ. Neurotoxic activation of glutamate receptors induces an extended neuronal depolarization in cultured hippocampal neurons. Brain Research. 566: 316-9. PMID 1687663 DOI: 10.1016/0006-8993(91)91716-E |
0.307 |
|
1990 |
Churn SB, Taft WC, Billingsley MS, Blair RE, DeLorenzo RJ. Temperature modulation of ischemic neuronal death and inhibition of calcium/calmodulin-dependent protein kinase II in gerbils. Stroke; a Journal of Cerebral Circulation. 21: 1715-21. PMID 2264078 |
0.359 |
|
1990 |
Churn SB, Taft WC, DeLorenzo RJ. Effects of ischemia on multifunctional calcium/calmodulin-dependent protein kinase type II in the gerbil. Stroke; a Journal of Cerebral Circulation. 21: III112-6. PMID 2173173 |
0.333 |
|
1989 |
Taft WC, Clifton GL, Blair RE, DeLorenzo RJ. Phenytoin protects against ischemia-produced neuronal cell death. Brain Research. 483: 143-8. PMID 2706503 DOI: 10.1016/0006-8993(89)90045-0 |
0.367 |
|
1988 |
Taft WC, Tennes-Rees KA, Blair RE, Clifton GL, DeLorenzo RJ. Cerebral ischemia decreases endogenous calcium-dependent protein phosphorylation in gerbil brain. Brain Research. 447: 159-63. PMID 2838127 DOI: 10.1016/0006-8993(88)90978-X |
0.319 |
|
1987 |
Taft WC, Goldenring JR, DeLorenzo RJ. Molecular mechanisms of neuronal excitability: possible involvement of CaM kinase II in seizure activity. Advances in Experimental Medicine and Biology. 221: 409-25. PMID 2829586 DOI: 10.1007/978-1-4684-7618-7_30 |
0.347 |
|
1987 |
Taft WC, DeLorenzo RJ. Regulation of calcium channels in brain: implications for the clinical neurosciences. The Yale Journal of Biology and Medicine. 60: 99-106. PMID 2437710 |
0.351 |
|
1986 |
DeLorenzo RJ. A molecular approach to the calcium signal in brain: relationship to synaptic modulation and seizure discharge. Advances in Neurology. 44: 435-64. PMID 3010680 |
0.369 |
|
1986 |
DeLorenzo RJ, Bowling AC, Taft WC. A molecular approach to the development of anticonvulsants. Annals of the New York Academy of Sciences. 477: 238-46. PMID 2433983 |
0.32 |
|
1985 |
Johansen J, Taft WC, Yang J, Kleinhaus AL, DeLorenzo RJ. Inhibition of Ca2+ conductance in identified leech neurons by benzodiazepines. Proceedings of the National Academy of Sciences of the United States of America. 82: 3935-9. PMID 3858853 |
0.322 |
|
1984 |
DeLorenzo RJ. Calmodulin systems in neuronal excitability: a molecular approach to epilepsy. Annals of Neurology. 16: S104-14. PMID 6150680 |
0.35 |
|
1975 |
Walton KG, DeLorenzo RJ, Curran PF, Greengard P. Regulation of protein phosphorylation and sodium transport in toad bladder. The Journal of General Physiology. 65: 153-77. PMID 163889 DOI: 10.1085/jgp.65.2.153 |
0.325 |
|
1973 |
Delorenzo RJ, Greengard P. Activation by adenosine 3':5'-monophosphate of a membrane-bound phosphoprotein phosphatase from toad bladder. Proceedings of the National Academy of Sciences of the United States of America. 70: 1831-5. PMID 4352657 DOI: 10.1073/pnas.70.6.1831 |
0.31 |
|
1973 |
DeLorenzo RJ, Walton KG, Curran PF, Greengard P. Regulation of phosphorylation of a specific protein in toad-bladder membrane by antidiuretic hormone and cyclic AMP, and its possible relationship to membrane permeability changes. Proceedings of the National Academy of Sciences of the United States of America. 70: 880-4. PMID 4351809 DOI: 10.1073/pnas.70.3.880 |
0.322 |
|
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