Billy R. Martin - Publications

Affiliations: 
Virginia Commonwealth University, Richmond, VA, United States 
Area:
Behavioral Pharmacology of Cannabinoids

243 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Majmudar JD, Konopko AM, Labby KJ, Tom CT, Crellin JE, Prakash A, Martin BR. Harnessing redox cross-reactivity to profile distinct cysteine modifications. Journal of the American Chemical Society. PMID 26780921 DOI: 10.1021/jacs.5b06806  1
2015 Foe IT, Child MA, Majmudar JD, Krishnamurthy S, van der Linden WA, Ward GE, Martin BR, Bogyo M. Global Analysis of Palmitoylated Proteins in Toxoplasma gondii. Cell Host & Microbe. 18: 501-11. PMID 26468752 DOI: 10.1016/j.chom.2015.09.006  1
2015 Xu H, Majmudar JD, Davda D, Ghanakota P, Kim KH, Carlson HA, Showalter HD, Martin BR, Amidon GL. Substrate-Competitive Activity-Based Profiling of Ester Prodrug Activating Enzymes Molecular Pharmaceutics. 12: 3399-3407. DOI: 10.1021/acs.molpharmaceut.5b00414  1
2014 Davda D, Martin BR. Acyl protein thioesterase inhibitors as probes of dynamic S-palmitoylation. Medchemcomm. 5: 268-276. PMID 25558349 DOI: 10.1039/C3MD00333G  1
2014 Jia L, Chisari M, Maktabi MH, Sobieski C, Zhou H, Konopko AM, Martin BR, Mennerick SJ, Blumer KJ. A mechanism regulating G protein-coupled receptor signaling that requires cycles of protein palmitoylation and depalmitoylation. The Journal of Biological Chemistry. 289: 6249-57. PMID 24385443 DOI: 10.1074/jbc.M113.531475  1
2014 Martin BR. The next frontier of post-translational modifications. Biopolymers. 101: 131-2. PMID 23913022 DOI: 10.1002/bip.22370  1
2014 Majmudar JD, Martin BR. Strategies for profiling native S-nitrosylation. Biopolymers. 101: 173-9. PMID 23828013 DOI: 10.1002/bip.22342  1
2013 Martin BR. Nonradioactive analysis of dynamic protein palmitoylation. Current Protocols in Protein Science / Editorial Board, John E. Coligan ... [Et Al.]. 73: Unit 14.15. PMID 24510591 DOI: 10.1002/0471140864.ps1415s73  1
2013 Davda D, El Azzouny MA, Tom CT, Hernandez JL, Majmudar JD, Kennedy RT, Martin BR. Profiling targets of the irreversible palmitoylation inhibitor 2-bromopalmitate. Acs Chemical Biology. 8: 1912-7. PMID 23844586 DOI: 10.1021/cb400380s  1
2013 Martin BR. Chemical approaches for profiling dynamic palmitoylation. Biochemical Society Transactions. 41: 43-9. PMID 23356256 DOI: 10.1042/BST20120271  1
2013 Hernandez JL, Majmudar JD, Martin BR. Profiling and inhibiting reversible palmitoylation. Current Opinion in Chemical Biology. 17: 20-6. PMID 23287289 DOI: 10.1016/j.cbpa.2012.11.023  1
2013 Tom CT, Martin BR. Fat chance! Getting a grip on a slippery modification. Acs Chemical Biology. 8: 46-57. PMID 23215442 DOI: 10.1021/cb300607e  1
2012 Adibekian A, Martin BR, Chang JW, Hsu KL, Tsuboi K, Bachovchin DA, Speers AE, Brown SJ, Spicer T, Fernandez-Vega V, Ferguson J, Hodder PS, Rosen H, Cravatt BF. Confirming target engagement for reversible inhibitors in vivo by kinetically tuned activity-based probes. Journal of the American Chemical Society. 134: 10345-8. PMID 22690931 DOI: 10.1021/ja303400u  1
2012 Ivaldi C, Martin BR, Kieffer-Jaquinod S, Chapel A, Levade T, Garin J, Journet A. Proteomic analysis of S-acylated proteins in human B cells reveals palmitoylation of the immune regulators CD20 and CD23. Plos One. 7: e37187. PMID 22615937 DOI: 10.1371/journal.pone.0037187  1
2012 Wiley JL, Smith VJ, Chen J, Martin BR, Huffman JW. Synthesis and pharmacology of 1-alkyl-3-(1-naphthoyl)indoles: steric and electronic effects of 4- and 8-halogenated naphthoyl substituents. Bioorganic & Medicinal Chemistry. 20: 2067-81. PMID 22341572 DOI: 10.1016/j.bmc.2012.01.038  1
2012 Wiley JL, Marusich JA, Martin BR, Huffman JW. 1-Pentyl-3-phenylacetylindoles and JWH-018 share in vivo cannabinoid profiles in mice. Drug and Alcohol Dependence. 123: 148-53. PMID 22127210 DOI: 10.1016/j.drugalcdep.2011.11.001  1
2012 Li Y, Martin BR, Cravatt BF, Hofmann SL. DHHC5 protein palmitoylates flotillin-2 and is rapidly degraded on induction of neuronal differentiation in cultured cells. The Journal of Biological Chemistry. 287: 523-30. PMID 22081607 DOI: 10.1074/jbc.M111.306183  1
2012 Martin BR, Wang C, Adibekian A, Tully SE, Cravatt BF. Global profiling of dynamic protein palmitoylation. Nature Methods. 9: 84-9. PMID 22056678 DOI: 10.1038/nmeth.1769  1
2011 Adibekian A, Martin BR, Wang C, Hsu KL, Bachovchin DA, Niessen S, Hoover H, Cravatt BF. Click-generated triazole ureas as ultrapotent in vivo-active serine hydrolase inhibitors. Nature Chemical Biology. 7: 469-78. PMID 21572424 DOI: 10.1038/nchembio.579  1
2011 Ladygina N, Martin BR, Altman A. Dynamic palmitoylation and the role of DHHC proteins in T cell activation and anergy. Advances in Immunology. 109: 1-44. PMID 21569911 DOI: 10.1016/B978-0-12-387664-5.00001-7  1
2011 Wiley JL, Breivogel CS, Mahadevan A, Pertwee RG, Cascio MG, Bolognini D, Huffman JW, Walentiny DM, Vann RE, Razdan RK, Martin BR. Structural and pharmacological analysis of O-2050, a putative neutral cannabinoid CB(1) receptor antagonist. European Journal of Pharmacology. 651: 96-105. PMID 21114999 DOI: 10.1016/j.ejphar.2010.10.085  1
2010 Huffman JW, Hepburn SA, Lyutenko N, Thompson AL, Wiley JL, Selley DE, Martin BR. 1-Bromo-3-(1',1'-dimethylalkyl)-1-deoxy-Δ(8)-tetrahydrocannabinols: New selective ligands for the cannabinoid CB(2) receptor. Bioorganic & Medicinal Chemistry. 18: 7809-15. PMID 20943404 DOI: 10.1016/j.bmc.2010.09.061  1
2010 Huffman JW, Hepburn SA, Reggio PH, Hurst DP, Wiley JL, Martin BR. Synthesis and pharmacology of 1-methoxy analogs of CP-47,497. Bioorganic & Medicinal Chemistry. 18: 5475-82. PMID 20621488 DOI: 10.1016/j.bmc.2010.06.054  1
2010 Carroll FI, Ma W, Deng L, Navarro HA, Damaj MI, Martin BR. Synthesis, nicotinic acetylcholine receptor binding, and antinociceptive properties of 3'-(substituted phenyl)epibatidine analogues. Nicotinic partial agonists. Journal of Natural Products. 73: 306-12. PMID 20038125 DOI: 10.1021/np9006124  1
2009 Jackson KJ, Walters CL, Miles MF, Martin BR, Damaj MI. Characterization of pharmacological and behavioral differences to nicotine in C57Bl/6 and DBA/2 mice. Neuropharmacology. 57: 347-55. PMID 19619563 DOI: 10.1016/j.neuropharm.2009.07.020  1
2009 Grider JR, Mahavadi S, Li Y, Qiao LY, Kuemmerle JF, Murthy KS, Martin BR. Modulation of motor and sensory pathways of the peristaltic reflex by cannabinoids. American Journal of Physiology. Gastrointestinal and Liver Physiology. 297: G539-49. PMID 19589944 DOI: 10.1152/ajpgi.00064.2009  1
2009 Blair RE, Deshpande LS, Sombati S, Elphick MR, Martin BR, DeLorenzo RJ. Prolonged exposure to WIN55,212-2 causes downregulation of the CB1 receptor and the development of tolerance to its anticonvulsant effects in the hippocampal neuronal culture model of acquired epilepsy. Neuropharmacology. 57: 208-18. PMID 19540252 DOI: 10.1016/j.neuropharm.2009.06.007  1
2009 Vann RE, Warner JA, Bushell K, Huffman JW, Martin BR, Wiley JL. Discriminative stimulus properties of delta9-tetrahydrocannabinol (THC) in C57Bl/6J mice. European Journal of Pharmacology. 615: 102-7. PMID 19470387 DOI: 10.1016/j.ejphar.2009.05.010  1
2009 Jackson KJ, Kota DH, Martin BR, Damaj MI. The role of various nicotinic receptor subunits and factors influencing nicotine conditioned place aversion. Neuropharmacology. 56: 970-4. PMID 19371584 DOI: 10.1016/j.neuropharm.2009.01.023  1
2009 Falenski KW, Carter DS, Harrison AJ, Martin BR, Blair RE, DeLorenzo RJ. Temporal characterization of changes in hippocampal cannabinoid CB(1) receptor expression following pilocarpine-induced status epilepticus. Brain Research. 1262: 64-72. PMID 19368833 DOI: 10.1016/j.brainres.2009.01.036  1
2009 Zhang M, Martin BR, Adler MW, Razdan RJ, Kong W, Ganea D, Tuma RF. Modulation of cannabinoid receptor activation as a neuroprotective strategy for EAE and stroke. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 4: 249-59. PMID 19255856 DOI: 10.1007/s11481-009-9148-4  1
2009 Martin BR, Cravatt BF. Large-scale profiling of protein palmitoylation in mammalian cells. Nature Methods. 6: 135-8. PMID 19137006 DOI: 10.1038/nmeth.1293  1
2008 Abdrakhmanova GR, Carroll FI, Damaj MI, Martin BR. 3'-Fluoro substitution in the pyridine ring of epibatidine improves selectivity and efficacy for alpha4beta2 versus alpha3beta4 nAChRs. Neuropharmacology. 55: 1287-92. PMID 18775444 DOI: 10.1016/j.neuropharm.2008.08.007  1
2008 Merritt LL, Martin BR, Walters C, Lichtman AH, Damaj MI. The endogenous cannabinoid system modulates nicotine reward and dependence. The Journal of Pharmacology and Experimental Therapeutics. 326: 483-92. PMID 18451315 DOI: 10.1124/jpet.108.138321  1
2008 Kota D, Martin BR, Damaj MI. Age-dependent differences in nicotine reward and withdrawal in female mice. Psychopharmacology. 198: 201-10. PMID 18338157 DOI: 10.1007/s00213-008-1117-8  1
2008 Zhang M, Martin BR, Adler MW, Razdan RK, Ganea D, Tuma RF. Modulation of the balance between cannabinoid CB(1) and CB(2) receptor activation during cerebral ischemic/reperfusion injury. Neuroscience. 152: 753-60. PMID 18304750 DOI: 10.1016/j.neuroscience.2008.01.022  1
2008 Perrotti LI, Weaver RR, Robison B, Renthal W, Maze I, Yazdani S, Elmore RG, Knapp DJ, Selley DE, Martin BR, Sim-Selley L, Bachtell RK, Self DW, Nestler EJ. Distinct patterns of DeltaFosB induction in brain by drugs of abuse. Synapse (New York, N.Y.). 62: 358-69. PMID 18293355 DOI: 10.1002/syn.20500  1
2008 Raborn ES, Marciano-Cabral F, Buckley NE, Martin BR, Cabral GA. The cannabinoid delta-9-tetrahydrocannabinol mediates inhibition of macrophage chemotaxis to RANTES/CCL5: linkage to the CB2 receptor. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 3: 117-29. PMID 18247131 DOI: 10.1007/s11481-007-9077-z  1
2008 Vann RE, Gamage TF, Warner JA, Marshall EM, Taylor NL, Martin BR, Wiley JL. Divergent effects of cannabidiol on the discriminative stimulus and place conditioning effects of Delta(9)-tetrahydrocannabinol. Drug and Alcohol Dependence. 94: 191-8. PMID 18206320 DOI: 10.1016/j.drugalcdep.2007.11.017  1
2008 Jackson KJ, Martin BR, Changeux JP, Damaj MI. Differential role of nicotinic acetylcholine receptor subunits in physical and affective nicotine withdrawal signs. The Journal of Pharmacology and Experimental Therapeutics. 325: 302-12. PMID 18184829 DOI: 10.1124/jpet.107.132977  1
2008 McKinney DL, Cassidy MP, Collier LM, Martin BR, Wiley JL, Selley DE, Sim-Selley LJ. Dose-related differences in the regional pattern of cannabinoid receptor adaptation and in vivo tolerance development to delta9-tetrahydrocannabinol. The Journal of Pharmacology and Experimental Therapeutics. 324: 664-73. PMID 17967938 DOI: 10.1124/jpet.107.130328  1
2008 Ivy Carroll F, Yokota Y, Ma W, Lee JR, Brieaddy LE, Burgess JP, Navarro HA, Damaj MI, Martin BR. Synthesis, nicotinic acetylcholine receptor binding, and pharmacological properties of 3'-(substituted phenyl)deschloroepibatidine analogs. Bioorganic & Medicinal Chemistry. 16: 746-54. PMID 17964169 DOI: 10.1016/j.bmc.2007.10.027  1
2008 Huffman JW, Thompson AL, Wiley JL, Martin BR. Synthesis and pharmacology of 1-deoxy analogs of CP-47,497 and CP-55,940. Bioorganic & Medicinal Chemistry. 16: 322-35. PMID 17919913 DOI: 10.1016/j.bmc.2007.09.033  1
2007 Rock RB, Gekker G, Hu S, Sheng WS, Cabral GA, Martin BR, Peterson PK. WIN55,212-2-mediated inhibition of HIV-1 expression in microglial cells: involvement of cannabinoid receptors. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 2: 178-83. PMID 18040842 DOI: 10.1007/s11481-006-9040-4  1
2007 Carroll FI, Robinson TP, Brieaddy LE, Atkinson RN, Mascarella SW, Damaj MI, Martin BR, Navarro HA. Synthesis and nicotinic acetylcholine receptor binding properties of bridged and fused ring analogues of epibatidine. Journal of Medicinal Chemistry. 50: 6383-91. PMID 17994682 DOI: 10.1021/jm0704696  1
2007 Martin BR, Deerinck TJ, Ellisman MH, Taylor SS, Tsien RY. Isoform-specific PKA dynamics revealed by dye-triggered aggregation and DAKAP1alpha-mediated localization in living cells. Chemistry & Biology. 14: 1031-42. PMID 17884635 DOI: 10.1016/j.chembiol.2007.07.017  1
2007 Bourne C, Roy S, Wiley JL, Martin BR, Thomas BF, Mahadevan A, Razdan RK. Novel, potent THC/anandamide (hybrid) analogs. Bioorganic & Medicinal Chemistry. 15: 7850-64. PMID 17827022 DOI: 10.1016/j.bmc.2007.08.039  1
2007 Gehani NC, Nalwalk JW, Razdan RK, Martin BR, Sun X, Wentland M, Abood ME, Hough LB. Significance of cannabinoid CB1 receptors in improgan antinociception. The Journal of Pain : Official Journal of the American Pain Society. 8: 850-60. PMID 17644043 DOI: 10.1016/j.jpain.2007.05.015  1
2007 Niyuhire F, Varvel SA, Martin BR, Lichtman AH. Exposure to marijuana smoke impairs memory retrieval in mice. The Journal of Pharmacology and Experimental Therapeutics. 322: 1067-75. PMID 17586723 DOI: 10.1124/jpet.107.119594  1
2007 Varvel SA, Martin BR, Lichtman AH. Lack of behavioral sensitization after repeated exposure to THC in mice and comparison to methamphetamine. Psychopharmacology. 193: 511-9. PMID 17497137 DOI: 10.1007/s00213-007-0811-2  1
2007 Kota D, Martin BR, Robinson SE, Damaj MI. Nicotine dependence and reward differ between adolescent and adult male mice. The Journal of Pharmacology and Experimental Therapeutics. 322: 399-407. PMID 17446302 DOI: 10.1124/jpet.107.121616  1
2007 Falenski KW, Blair RE, Sim-Selley LJ, Martin BR, DeLorenzo RJ. Status epilepticus causes a long-lasting redistribution of hippocampal cannabinoid type 1 receptor expression and function in the rat pilocarpine model of acquired epilepsy. Neuroscience. 146: 1232-44. PMID 17433556 DOI: 10.1016/j.neuroscience.2007.01.065  1
2007 Damaj MI, Fonck C, Marks MJ, Deshpande P, Labarca C, Lester HA, Collins AC, Martin BR. Genetic approaches identify differential roles for alpha4beta2* nicotinic receptors in acute models of antinociception in mice. The Journal of Pharmacology and Experimental Therapeutics. 321: 1161-9. PMID 17371806 DOI: 10.1124/jpet.106.112649  1
2007 Deshpande LS, Blair RE, Nagarkatti N, Sombati S, Martin BR, DeLorenzo RJ. Development of pharmacoresistance to benzodiazepines but not cannabinoids in the hippocampal neuronal culture model of status epilepticus. Experimental Neurology. 204: 705-13. PMID 17289026 DOI: 10.1016/j.expneurol.2007.01.001  1
2007 Chen X, Che Y, Zhang L, Putman AH, Damaj I, Martin BR, Kendler KS, Miles MF. RhoA, encoding a Rho GTPase, is associated with smoking initiation. Genes, Brain, and Behavior. 6: 689-97. PMID 17284169 DOI: 10.1111/j.1601-183X.2006.00296.x  1
2007 Naidu PS, Varvel SA, Ahn K, Cravatt BF, Martin BR, Lichtman AH. Evaluation of fatty acid amide hydrolase inhibition in murine models of emotionality. Psychopharmacology. 192: 61-70. PMID 17279376 DOI: 10.1007/s00213-006-0689-4  1
2007 Crocker PJ, Mahadevan A, Wiley JL, Martin BR, Razdan RK. The role of fluorine substitution in the structure-activity relationships (SAR) of classical cannabinoids. Bioorganic & Medicinal Chemistry Letters. 17: 1504-7. PMID 17257842 DOI: 10.1016/j.bmcl.2007.01.006  1
2007 Zhang M, Martin BR, Adler MW, Razdan RK, Jallo JI, Tuma RF. Cannabinoid CB(2) receptor activation decreases cerebral infarction in a mouse focal ischemia/reperfusion model. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 27: 1387-96. PMID 17245417 DOI: 10.1038/sj.jcbfm.9600447  1
2007 Pertwee RG, Thomas A, Stevenson LA, Ross RA, Varvel SA, Lichtman AH, Martin BR, Razdan RK. The psychoactive plant cannabinoid, Delta9-tetrahydrocannabinol, is antagonized by Delta8- and Delta9-tetrahydrocannabivarin in mice in vivo. British Journal of Pharmacology. 150: 586-94. PMID 17245367 DOI: 10.1038/sj.bjp.0707124  1
2007 Wise LE, Shelton CC, Cravatt BF, Martin BR, Lichtman AH. Assessment of anandamide's pharmacological effects in mice deficient of both fatty acid amide hydrolase and cannabinoid CB1 receptors. European Journal of Pharmacology. 557: 44-8. PMID 17217945 DOI: 10.1016/j.ejphar.2006.11.002  1
2007 Deshpande LS, Blair RE, Ziobro JM, Sombati S, Martin BR, DeLorenzo RJ. Endocannabinoids block status epilepticus in cultured hippocampal neurons. European Journal of Pharmacology. 558: 52-9. PMID 17174949 DOI: 10.1016/j.ejphar.2006.11.030  1
2007 Deshpande LS, Sombati S, Blair RE, Carter DS, Martin BR, DeLorenzo RJ. Cannabinoid CB1 receptor antagonists cause status epilepticus-like activity in the hippocampal neuronal culture model of acquired epilepsy. Neuroscience Letters. 411: 11-6. PMID 17110038 DOI: 10.1016/j.neulet.2006.09.046  1
2007 Vann RE, Cook CD, Martin BR, Wiley JL. Cannabimimetic properties of ajulemic acid. The Journal of Pharmacology and Experimental Therapeutics. 320: 678-86. PMID 17105826 DOI: 10.1124/jpet.106.111625  1
2007 Ivy Carroll F, Ma W, Navarro HA, Abraham P, Wolckenhauer SA, Damaj MI, Martin BR. Synthesis, nicotinic acetylcholine receptor binding, antinociceptive and seizure properties of methyllycaconitine analogs. Bioorganic & Medicinal Chemistry. 15: 678-85. PMID 17098430 DOI: 10.1016/j.bmc.2006.10.061  1
2007 Damaj MI, Siu EC, Sellers EM, Tyndale RF, Martin BR. Inhibition of nicotine metabolism by methoxysalen: Pharmacokinetic and pharmacological studies in mice. The Journal of Pharmacology and Experimental Therapeutics. 320: 250-7. PMID 17021260 DOI: 10.1124/jpet.106.111237  1
2006 Marciano-Cabral F, Raborn ES, Martin BR, Cabral GA. Delta-9-tetrahydrocannabinol, the major psychoactive component in marijuana, inhibits macrophage chemotaxis to Acanthamoeba. The Journal of Eukaryotic Microbiology. 53: S15-7. PMID 17169039 DOI: 10.1111/j.1550-7408.2006.00158.x  1
2006 Wiley JL, Razdan RK, Martin BR. Evaluation of the role of the arachidonic acid cascade in anandamide's in vivo effects in mice. Life Sciences. 80: 24-35. PMID 16978656 DOI: 10.1016/j.lfs.2006.08.017  1
2006 Wilson DM, Varvel SA, Harloe JP, Martin BR, Lichtman AH. SR 141716 (Rimonabant) precipitates withdrawal in marijuana-dependent mice. Pharmacology, Biochemistry, and Behavior. 85: 105-13. PMID 16934319 DOI: 10.1016/j.pbb.2006.07.018  1
2006 Huffman JW, Padgett LW, Isherwood ML, Wiley JL, Martin BR. 1-Alkyl-2-aryl-4-(1-naphthoyl)pyrroles: new high affinity ligands for the cannabinoid CB1 and CB2 receptors. Bioorganic & Medicinal Chemistry Letters. 16: 5432-5. PMID 16889960 DOI: 10.1016/j.bmcl.2006.07.051  1
2006 Damaj MI, Zheng J, Martin BR, Kuhar MJ. Intrathecal CART (55-102) attenuates hyperlagesia and allodynia in a mouse model of neuropathic but not inflammatory pain. Peptides. 27: 2019-23. PMID 16814901 DOI: 10.1016/j.peptides.2005.09.019  1
2006 Sim-Selley LJ, Schechter NS, Rorrer WK, Dalton GD, Hernandez J, Martin BR, Selley DE. Prolonged recovery rate of CB1 receptor adaptation after cessation of long-term cannabinoid administration. Molecular Pharmacology. 70: 986-96. PMID 16760363 DOI: 10.1124/mol.105.019612  1
2006 Martin BR, Wiley JL, Beletskaya I, Sim-Selley LJ, Smith FL, Dewey WL, Cottney J, Adams J, Baker J, Hill D, Saha B, Zerkowski J, Mahadevan A, Razdan RK. Pharmacological characterization of novel water-soluble cannabinoids. The Journal of Pharmacology and Experimental Therapeutics. 318: 1230-9. PMID 16757541 DOI: 10.1124/jpet.106.104109  1
2006 Carroll FI, Hu X, Navarro HA, Deschamps J, Abdrakhmanova GR, Damaj MI, Martin BR. Synthesis and pharmacological characterization of nicotinic acetylcholine receptor properties of (+)- and (-)-pyrido-[3,4-b]homotropanes. Journal of Medicinal Chemistry. 49: 3244-50. PMID 16722642 DOI: 10.1021/jm060122n  1
2006 Varvel SA, Wiley JL, Yang R, Bridgen DT, Long K, Lichtman AH, Martin BR. Interactions between THC and cannabidiol in mouse models of cannabinoid activity. Psychopharmacology. 186: 226-34. PMID 16572263 DOI: 10.1007/s00213-006-0356-9  1
2006 Abdrakhmanova GR, Damaj MI, Carroll FI, Martin BR. 2-Fluoro-3-(4-nitro-phenyl)deschloroepibatidine is a novel potent competitive antagonist of human neuronal alpha4beta2 nAChRs. Molecular Pharmacology. 69: 1945-52. PMID 16505153 DOI: 10.1124/mol.105.021782  1
2006 Blair RE, Deshpande LS, Sombati S, Falenski KW, Martin BR, DeLorenzo RJ. Activation of the cannabinoid type-1 receptor mediates the anticonvulsant properties of cannabinoids in the hippocampal neuronal culture models of acquired epilepsy and status epilepticus. The Journal of Pharmacology and Experimental Therapeutics. 317: 1072-8. PMID 16469864 DOI: 10.1124/jpet.105.100354  1
2006 Bisogno T, Cascio MG, Saha B, Mahadevan A, Urbani P, Minassi A, Appendino G, Saturnino C, Martin B, Razdan R, Di Marzo V. Development of the first potent and specific inhibitors of endocannabinoid biosynthesis Biochimica Et Biophysica Acta - Molecular and Cell Biology of Lipids. 1761: 205-212. PMID 16466961 DOI: 10.1016/j.bbalip.2005.12.009  1
2006 Grabus SD, Martin BR, Brown SE, Damaj MI. Nicotine place preference in the mouse: influences of prior handling, dose and strain and attenuation by nicotinic receptor antagonists. Psychopharmacology. 184: 456-63. PMID 16463055 DOI: 10.1007/s00213-006-0305-7  1
2006 Walters CL, Brown S, Changeux JP, Martin B, Damaj MI. The beta2 but not alpha7 subunit of the nicotinic acetylcholine receptor is required for nicotine-conditioned place preference in mice. Psychopharmacology. 184: 339-44. PMID 16416156 DOI: 10.1007/s00213-005-0295-x  1
2006 Marriott KS, Huffman JW, Wiley JL, Martin BR. Synthesis and pharmacology of 11-nor-1-methoxy-9-hydroxyhexahydrocannabinols and 11-nor-1-deoxy-9-hydroxyhexahydrocannabinols: new selective ligands for the cannabinoid CB2 receptor. Bioorganic & Medicinal Chemistry. 14: 2386-97. PMID 16321538 DOI: 10.1016/j.bmc.2005.11.023  1
2006 Ligresti A, Cascio MG, Pryce G, Kulasegram S, Beletskaya I, De Petrocellis L, Saha B, Mahadevan A, Visintin C, Wiley JL, Baker D, Martin BR, Razdan RK, Di Marzo V. New potent and selective inhibitors of anandamide reuptake with antispastic activity in a mouse model of multiple sclerosis. British Journal of Pharmacology. 147: 83-91. PMID 16284631 DOI: 10.1038/sj.bjp.0706418  1
2006 Huffman JW, Bushell SM, Joshi SN, Wiley JL, Martin BR. Enantioselective synthesis of 1-methoxy- and 1-deoxy-2'-methyl-delta8-tetrahydrocannabinols: new selective ligands for the CB2 receptor. Bioorganic & Medicinal Chemistry. 14: 247-62. PMID 16165365 DOI: 10.1016/j.bmc.2005.08.013  1
2006 Lichtman AH, Martin BR. Understanding the pharmacology and physiology of cannabis dependence Cannabis Dependence: Its Nature, Consequences, and Treatment. 37-57. DOI: 10.1017/CBO9780511544248.005  1
2005 Lichtman AH, Martin BR. Cannabinoid tolerance and dependence. Handbook of Experimental Pharmacology. 691-717. PMID 16596793 DOI: 10.1007/3-540-26573-2-24  1
2005 Carroll FI, Brieaddy LE, Navarro HA, Damaj MI, Martin BR. Synthesis and pharmacological characterization of exo-2-(2'-chloro-5-pyridinyl)-7-(endo and exo)-aminobicyclo[2.2.1]heptanes as novel epibatidine analogues. Journal of Medicinal Chemistry. 48: 7491-5. PMID 16279810 DOI: 10.1021/jm058243v  1
2005 Damaj MI, Wiley JL, Martin BR, Papke RL. In vivo characterization of a novel inhibitor of CNS nicotinic receptors. European Journal of Pharmacology. 521: 43-8. PMID 16181622 DOI: 10.1016/j.ejphar.2005.06.056  1
2005 Vandevoorde S, Saha B, Mahadevan A, Razdan RK, Pertwee RG, Martin BR, Fowler CJ. Influence of the degree of unsaturation of the acyl side chain upon the interaction of analogues of 1-arachidonoylglycerol with monoacylglycerol lipase and fatty acid amide hydrolase. Biochemical and Biophysical Research Communications. 337: 104-9. PMID 16181610 DOI: 10.1016/j.bbrc.2005.09.015  1
2005 Martin BR, Giepmans BN, Adams SR, Tsien RY. Mammalian cell-based optimization of the biarsenical-binding tetracysteine motif for improved fluorescence and affinity. Nature Biotechnology. 23: 1308-14. PMID 16155565 DOI: 10.1038/nbt1136  1
2005 Dukat M, Ramunno A, Banzi R, Damaj MI, Martin B, Glennon RA. 3-(2-Aminoethyl)pyridine analogs as α4β2 nicotinic cholinergic receptor ligands Bioorganic and Medicinal Chemistry Letters. 15: 4308-4312. PMID 16039854 DOI: 10.1016/j.bmcl.2005.06.053  1
2005 Huffman JW, Szklennik PV, Almond A, Bushell K, Selley DE, He H, Cassidy MP, Wiley JL, Martin BR. 1-Pentyl-3-phenylacetylindoles, a new class of cannabimimetic indoles. Bioorganic & Medicinal Chemistry Letters. 15: 4110-3. PMID 16005223 DOI: 10.1016/j.bmcl.2005.06.008  1
2005 Martin BR. Role of lipids and lipid signaling in the development of cannabinoid tolerance. Life Sciences. 77: 1543-58. PMID 15949820 DOI: 10.1016/j.lfs.2005.05.005  1
2005 Ramunno A, Dukat M, Lee M, Young R, El-Zahabi M, Damaj MI, Martin B, Glennon RA. 6-(2-Phenylethyl)nicotine: A novel nicotinic cholinergic receptor ligand Bioorganic and Medicinal Chemistry Letters. 15: 3237-3240. PMID 15925512 DOI: 10.1016/j.bmcl.2005.04.072  1
2005 Grabus SD, Martin BR, Imad Damaj M. Nicotine physical dependence in the mouse: involvement of the alpha7 nicotinic receptor subtype. European Journal of Pharmacology. 515: 90-3. PMID 15896732 DOI: 10.1016/j.ejphar.2005.03.044  1
2005 Varvel SA, Bridgen DT, Tao Q, Thomas BF, Martin BR, Lichtman AH. Delta9-tetrahydrocannbinol accounts for the antinociceptive, hypothermic, and cataleptic effects of marijuana in mice. The Journal of Pharmacology and Experimental Therapeutics. 314: 329-37. PMID 15831444 DOI: 10.1124/jpet.104.080739  1
2005 Wiley JL, Burston JJ, Leggett DC, Alekseeva OO, Razdan RK, Mahadevan A, Martin BR. CB1 cannabinoid receptor-mediated modulation of food intake in mice. British Journal of Pharmacology. 145: 293-300. PMID 15778743 DOI: 10.1038/sj.bjp.0706157  1
2005 Carroll FI, Ma W, Yokota Y, Lee JR, Brieaddy LE, Navarro HA, Damaj MI, Martin BR. Synthesis, nicotinic acetylcholine receptor binding, and antinociceptive properties of 3'-substituted deschloroepibatidine analogues. Novel nicotinic antagonists. Journal of Medicinal Chemistry. 48: 1221-8. PMID 15715488 DOI: 10.1021/jm040160b  1
2005 Huffman JW, Zengin G, Wu MJ, Lu J, Hynd G, Bushell K, Thompson AL, Bushell S, Tartal C, Hurst DP, Reggio PH, Selley DE, Cassidy MP, Wiley JL, Martin BR. Structure-activity relationships for 1-alkyl-3-(1-naphthoyl)indoles at the cannabinoid CB(1) and CB(2) receptors: steric and electronic effects of naphthoyl substituents. New highly selective CB(2) receptor agonists. Bioorganic & Medicinal Chemistry. 13: 89-112. PMID 15582455 DOI: 10.1016/j.bmc.2004.09.050  1
2005 Grabus SD, Martin BR, Batman AM, Tyndale RF, Sellers E, Damaj MI. Nicotine physical dependence and tolerance in the mouse following chronic oral administration. Psychopharmacology. 178: 183-92. PMID 15365686 DOI: 10.1007/s00213-004-2007-3  1
2005 Damaj MI, Flood P, Ho KK, May EL, Martin BR. Effect of dextrometorphan and dextrorphan on nicotine and neuronal nicotinic receptors: in vitro and in vivo selectivity. The Journal of Pharmacology and Experimental Therapeutics. 312: 780-5. PMID 15356218 DOI: 10.1124/jpet.104.075093  1
2005 Alekseeva OO, Mahadevan A, Wiley JL, Martin BR, Razdan RK. Synthesis of novel 5-substituted pyrazole derivatives as cannabinoid antagonists Tetrahedron Letters. 46: 2159-2161. DOI: 10.1016/j.tetlet.2005.01.165  1
2004 Ghafouri N, Tiger G, Razdan RK, Mahadevan A, Pertwee RG, Martin BR, Fowler CJ. Inhibition of monoacylglycerol lipase and fatty acid amide hydrolase by analogues of 2-arachidonoylglycerol. British Journal of Pharmacology. 143: 774-84. PMID 15492019 DOI: 10.1038/sj.bjp.0705948  1
2004 Damaj MI, Hunter RG, Martin BR, Kuhar MJ. Intrathecal CART (55-102) enhances the spinal analgesic actions of morphine in mice. Brain Research. 1024: 146-9. PMID 15451376 DOI: 10.1016/j.brainres.2004.07.058  1
2004 Martin BR, Wiley JL. Mechanism of action of cannabinoids: how it may lead to treatment of cachexia, emesis, and pain. The Journal of Supportive Oncology. 2: 305-14; discussion 3. PMID 15357514  1
2004 Damaj MI, Carroll FI, Eaton JB, Navarro HA, Blough BE, Mirza S, Lukas RJ, Martin BR. Enantioselective effects of hydroxy metabolites of bupropion on behavior and on function of monoamine transporters and nicotinic receptors. Molecular Pharmacology. 66: 675-82. PMID 15322260 DOI: 10.1124/mol.104.001313  1
2004 Carroll FI, Ware R, Brieaddy LE, Navarro HA, Damaj MI, Martin BR. Synthesis, nicotinic acetylcholine receptor binding, and antinociceptive properties of 2'-fluoro-3'-(substituted phenyl)deschloroepibatidine analogues. Novel nicotinic antagonist. Journal of Medicinal Chemistry. 47: 4588-94. PMID 15317468 DOI: 10.1021/jm040078g  1
2004 Wiley JL, LaVecchia KL, Karp NE, Kulasegram S, Mahadevan A, Razdan RK, Martin BR. A comparison of the discriminative stimulus effects of delta(9)-tetrahydrocannabinol and O-1812, a potent and metabolically stable anandamide analog, in rats. Experimental and Clinical Psychopharmacology. 12: 173-9. PMID 15301634 DOI: 10.1037/1064-1297.12.3.173  1
2004 Bass CE, Welch SP, Martin BR. Reversal of delta 9-tetrahydrocannabinol-induced tolerance by specific kinase inhibitors. European Journal of Pharmacology. 496: 99-108. PMID 15288581 DOI: 10.1016/j.ejphar.2004.06.009  1
2004 Selley DE, Cassidy MP, Martin BR, Sim-Selley LJ. Long-term administration of Delta9-tetrahydrocannabinol desensitizes CB1-, adenosine A1-, and GABAB-mediated inhibition of adenylyl cyclase in mouse cerebellum. Molecular Pharmacology. 66: 1275-84. PMID 15286206 DOI: 10.1124/mol.104.000604  1
2004 Dukat M, Taroua M, Dahdouh A, Siripurapu U, Damaj MI, Martin BR, Glennon RA. (+/-)8-Amino-5,6,7,8-tetrahydroisoquinolines as novel antinociceptive agents. Bioorganic & Medicinal Chemistry Letters. 14: 3651-4. PMID 15203136 DOI: 10.1016/j.bmcl.2004.05.020  1
2004 Martin BR, Sim-Selley LJ, Selley DE. Signaling pathways involved in the development of cannabinoid tolerance. Trends in Pharmacological Sciences. 25: 325-30. PMID 15165748 DOI: 10.1016/j.tips.2004.04.005  1
2004 Baskfield CY, Martin BR, Wiley JL. Differential effects of delta9-tetrahydrocannabinol and methanandamide in CB1 knockout and wild-type mice. The Journal of Pharmacology and Experimental Therapeutics. 309: 86-91. PMID 14718593 DOI: 10.1124/jpet.103.055376  1
2004 Dogruer D, Lee M, Dukat M, Damaj MI, Martin BR, Glennon RA. 3-(4-Aminobutyn-1-yl)pyridines: binding at alpha 4 beta 2 nicotinic cholinergic receptors. Bioorganic & Medicinal Chemistry Letters. 14: 523-6. PMID 14698195 DOI: 10.1016/j.bmcl.2003.10.033  1
2003 Simsek R, Chang-Fong J, Lee M, Dukat M, Imad Damaj M, Martin BR, Glennon RA. Quaternary ammonium 3-(aminoethoxy)pyridines as antinociceptive agents. Bioorganic & Medicinal Chemistry Letters. 13: 2917-20. PMID 14611857 DOI: 10.1016/S0960-894X(03)00585-7  1
2003 Damaj MI, Kao W, Martin BR. Characterization of spontaneous and precipitated nicotine withdrawal in the mouse. The Journal of Pharmacology and Experimental Therapeutics. 307: 526-34. PMID 12970387 DOI: 10.1124/jpet.103.054908  1
2003 Wallace MJ, Blair RE, Falenski KW, Martin BR, DeLorenzo RJ. The endogenous cannabinoid system regulates seizure frequency and duration in a model of temporal lobe epilepsy. The Journal of Pharmacology and Experimental Therapeutics. 307: 129-37. PMID 12954810 DOI: 10.1124/jpet.103.051920  1
2003 Damaj MI, Martin BR, Kuhar MJ. Antinociceptive effects of supraspinal rat cart (55-102) peptide in mice. Brain Research. 983: 233-6. PMID 12914986 DOI: 10.1016/S0006-8993(03)03094-4  1
2003 Wiley JL, Martin BR. Cannabinoid pharmacological properties common to other centrally acting drugs. European Journal of Pharmacology. 471: 185-93. PMID 12826237 DOI: 10.1016/S0014-2999(03)01856-9  1
2003 Ferretti G, Dukat M, Giannella M, Piergentili A, Pigini M, Quaglia W, Damaj MI, Martin BR, Glennon RA. Binding of nicotine and homoazanicotine analogues at neuronal nicotinic acetylcholinergic (nACh) receptors. Bioorganic & Medicinal Chemistry Letters. 13: 733-5. PMID 12639569 DOI: 10.1016/S0960-894X(02)01031-4  1
2003 Huffman JW, Miller JR, Liddle J, Yu S, Thomas BF, Wiley JL, Martin BR. Structure-activity relationships for 1',1'-dimethylalkyl-Delta8-tetrahydrocannabinols. Bioorganic & Medicinal Chemistry. 11: 1397-410. PMID 12628666 DOI: 10.1016/S0968-0896(02)00649-1  1
2003 Offertáler L, Mo FM, Bátkai S, Liu J, Begg M, Razdan RK, Martin BR, Bukoski RD, Kunos G. Selective ligands and cellular effectors of a G protein-coupled endothelial cannabinoid receptor. Molecular Pharmacology. 63: 699-705. PMID 12606780 DOI: 10.1124/mol.63.3.699  1
2003 Huffman JW, Mabon R, Wu MJ, Lu J, Hart R, Hurst DP, Reggio PH, Wiley JL, Martin BR. 3-Indolyl-1-naphthylmethanes: new cannabimimetic indoles provide evidence for aromatic stacking interactions with the CB(1) cannabinoid receptor. Bioorganic & Medicinal Chemistry. 11: 539-49. PMID 12538019 DOI: 10.1016/S0968-0896(02)00451-0  1
2003 Breivogel CS, Scates SM, Beletskaya IO, Lowery OB, Aceto MD, Martin BR. The effects of delta9-tetrahydrocannabinol physical dependence on brain cannabinoid receptors. European Journal of Pharmacology. 459: 139-50. PMID 12524139 DOI: 10.1016/S0014-2999(02)02854-6  1
2003 Darmani NA, Sim-Selley LJ, Martin BR, Janoyan JJ, Crim JL, Parekh B, Breivogel CS. Antiemetic and motor-depressive actions of CP55,940: cannabinoid CB1 receptor characterization, distribution, and G-protein activation. European Journal of Pharmacology. 459: 83-95. PMID 12505537  0.44
2002 Wiley JL, Martin BR. Cannabinoid pharmacology: implications for additional cannabinoid receptor subtypes. Chemistry and Physics of Lipids. 121: 57-63. PMID 12505690 DOI: 10.1016/S0009-3084(02)00146-9  1
2002 Huffman JW, Bushell SM, Miller JR, Wiley JL, Martin BR. 1-Methoxy-, 1-deoxy-11-hydroxy- and 11-hydroxy-1-methoxy-Delta(8)-tetrahydrocannabinols: new selective ligands for the CB2 receptor. Bioorganic & Medicinal Chemistry. 10: 4119-29. PMID 12413866 DOI: 10.1016/S0968-0896(02)00331-0  1
2002 Lichtman AH, Martin BR. Marijuana withdrawal syndrome in the animal model. Journal of Clinical Pharmacology. 42: 20S-27S. PMID 12412832  1
2002 Bass CE, Griffin G, Grier M, Mahadevan A, Razdan RK, Martin BR. SR-141716A-induced stimulation of locomotor activity. A structure-activity relationship study. Pharmacology, Biochemistry, and Behavior. 74: 31-40. PMID 12376150 DOI: 10.1016/S0091-3057(02)00945-0  1
2002 Carroll FI, Lee JR, Navarro HA, Ma W, Brieaddy LE, Abraham P, Damaj MI, Martin BR. Synthesis, nicotinic acetylcholine receptor binding, and antinociceptive properties of 2-exo-2-(2',3'-disubstituted 5'-pyridinyl)-7-azabicyclo[2.2.1]heptanes: epibatidine analogues. Journal of Medicinal Chemistry. 45: 4755-61. PMID 12361403  0.76
2002 Ferretti G, Dukat M, Giannella M, Piergentili A, Pigini M, Quaglia W, Damaj MI, Martin BR, Glennon RA. Homoazanicotine: a structure-affinity study for nicotinic acetylcholine (nACh) receptor binding. Journal of Medicinal Chemistry. 45: 4724-31. PMID 12361399 DOI: 10.1021/jm020188s  1
2002 Wallace MJ, Martin BR, DeLorenzo RJ. Evidence for a physiological role of endocannabinoids in the modulation of seizure threshold and severity. European Journal of Pharmacology. 452: 295-301. PMID 12359270 DOI: 10.1016/S0014-2999(02)02331-2  1
2002 Dukat M, El-Zahabi M, Ferretti G, Damaj MI, Martin BR, Young R, Glennon RA. (-)6-n-Propylnicotine antagonizes the antinociceptive effects of (-)nicotine. Bioorganic & Medicinal Chemistry Letters. 12: 3005-7. PMID 12270194 DOI: 10.1016/S0960-894X(02)00614-5  1
2002 Sim-Selley LJ, Martin BR. Effect of chronic administration of R-(+)-[2,3-Dihydro-5-methyl-3-[(morpholinyl)methyl]pyrrolo[1,2,3-de]-1,4-benzoxazinyl]-(1-naphthalenyl)methanone mesylate (WIN55,212-2) or delta(9)-tetrahydrocannabinol on cannabinoid receptor adaptation in mice. The Journal of Pharmacology and Experimental Therapeutics. 303: 36-44. PMID 12235230 DOI: 10.1124/jpet.102.035618  0.44
2002 Wiley JL, Jefferson RG, Griffin G, Liddle J, Yu S, Huffman JW, Martin BR. Paradoxical pharmacological effects of deoxy-tetrahydrocannabinol analogs lacking high CB1 receptor affinity. Pharmacology. 66: 89-99. PMID 12207116 DOI: 10.1159/000065631  1
2002 Wilson DM, Peart J, Martin BR, Bridgen DT, Byron PR, Lichtman AH. Physiochemical and pharmacological characterization of a Delta(9)-THC aerosol generated by a metered dose inhaler. Drug and Alcohol Dependence. 67: 259-67. PMID 12127197 DOI: 10.1016/S0376-8716(02)00078-9  1
2002 Lichtman AH, Varvel SA, Martin BR. Endocannabinoids in cognition and dependence. Prostaglandins, Leukotrienes, and Essential Fatty Acids. 66: 269-85. PMID 12052042 DOI: 10.1054/plef.2001.0351  1
2002 Howlett AC, Barth F, Bonner TI, Cabral G, Casellas P, Devane WA, Felder CC, Herkenham M, Mackie K, Martin BR, Mechoulam R, Pertwee RG. International Union of Pharmacology. XXVII. Classification of cannabinoid receptors. Pharmacological Reviews. 54: 161-202. PMID 12037135 DOI: 10.1124/pr.54.2.161  1
2002 Adams SR, Campbell RE, Gross LA, Martin BR, Walkup GK, Yao Y, Llopis J, Tsien RY. New biarsenical ligands and tetracysteine motifs for protein labeling in vitro and in vivo: synthesis and biological applications. Journal of the American Chemical Society. 124: 6063-76. PMID 12022841 DOI: 10.1021/ja017687n  1
2002 Wiley JL, Lavecchia KL, Martin BR, Damaj MI. Nicotine-like discriminative stimulus effects of bupropion in rats. Experimental and Clinical Psychopharmacology. 10: 129-35. PMID 12022798 DOI: 10.1037//1064-1297.10.2.129  1
2002 Wiley JL, Beletskaya ID, Ng EW, Dai Z, Crocker PJ, Mahadevan A, Razdan RK, Martin BR. Resorcinol derivatives: a novel template for the development of cannabinoid CB(1)/CB(2) and CB(2)-selective agonists. The Journal of Pharmacology and Experimental Therapeutics. 301: 679-89. PMID 11961073 DOI: 10.1124/jpet.301.2.679  1
2002 Di Marzo V, Griffin G, De Petrocellis L, Brandi I, Bisogno T, Williams W, Grier MC, Kulasegram S, Mahadevan A, Razdan RK, Martin BR. A structure/activity relationship study on arvanil, an endocannabinoid and vanilloid hybrid. The Journal of Pharmacology and Experimental Therapeutics. 300: 984-91. PMID 11861807  0.72
2002 Dukat M, Damaj IM, Young R, Vann R, Collins AC, Marks MJ, Martin BR, Glennon RA. Functional diversity among 5-substituted nicotine analogs; in vitro and in vivo investigations. European Journal of Pharmacology. 435: 171-80. PMID 11821023 DOI: 10.1016/S0014-2999(01)01570-9  1
2002 Martin BR, Jefferson RG, Winckler R, Wiley JL, Thomas BF, Crocker PJ, Williams W, Razdan RK. Assessment of structural commonality between tetrahydrocannabinol and anandamide. European Journal of Pharmacology. 435: 35-42. PMID 11790376 DOI: 10.1016/S0014-2999(01)01527-8  1
2001 Wallace MJ, Wiley JL, Martin BR, DeLorenzo RJ. Assessment of the role of CB1 receptors in cannabinoid anticonvulsant effects. European Journal of Pharmacology. 428: 51-7. PMID 11779037 DOI: 10.1016/S0014-2999(01)01243-2  1
2001 Carroll FI, Lee JR, Navarro HA, Brieaddy LE, Abraham P, Damaj MI, Martin BR. Synthesis, nicotinic acetylcholine receptor binding, and antinociceptive properties of 2-exo-2-(2'-substituted-3'-phenyl-5'-pyridinyl)-7-azabicyclo[2.2.1]heptanes. Novel nicotinic antagonist. Journal of Medicinal Chemistry. 44: 4039-41. PMID 11708907  0.76
2001 Huffman JW, Lu J, Hynd G, Wiley JL, Martin BR. A pyridone analogue of traditional cannabinoids. A new class of selective ligands for the CB(2) receptor. Bioorganic & Medicinal Chemistry. 9: 2863-70. PMID 11597467 DOI: 10.1016/S0968-0896(01)00155-9  1
2001 Varvel SA, Hamm RJ, Martin BR, Lichtman AH. Differential effects of delta 9-THC on spatial reference and working memory in mice. Psychopharmacology. 157: 142-50. PMID 11594438 DOI: 10.1007/s002130100780  1
2001 Lichtman AH, Sheikh SM, Loh HH, Martin BR. Opioid and cannabinoid modulation of precipitated withdrawal in delta(9)-tetrahydrocannabinol and morphine-dependent mice. The Journal of Pharmacology and Experimental Therapeutics. 298: 1007-14. PMID 11504797  1
2001 Cravatt BF, Demarest K, Patricelli MP, Bracey MH, Giang DK, Martin BR, Lichtman AH. Supersensitivity to anandamide and enhanced endogenous cannabinoid signaling in mice lacking fatty acid amide hydrolase. Proceedings of the National Academy of Sciences of the United States of America. 98: 9371-6. PMID 11470906 DOI: 10.1073/pnas.161191698  1
2001 Lichtman AH, Fisher J, Martin BR. Precipitated cannabinoid withdrawal is reversed by Delta(9)-tetrahydrocannabinol or clonidine. Pharmacology, Biochemistry, and Behavior. 69: 181-8. PMID 11420084 DOI: 10.1016/S0091-3057(01)00514-7  1
2001 Breivogel CS, Griffin G, Di Marzo V, Martin BR. Evidence for a new G protein-coupled cannabinoid receptor in mouse brain. Molecular Pharmacology. 60: 155-63. PMID 11408610  0.4
2001 Carroll FI, Liang F, Navarro HA, Brieaddy LE, Abraham P, Damaj MI, Martin BR. Synthesis, nicotinic acetylcholine receptor binding, and antinociceptive properties of 2-exo-2-(2'-substituted 5'-pyridinyl)-7-azabicyclo[2.2.1]heptanes. Epibatidine analogues. Journal of Medicinal Chemistry. 44: 2229-37. PMID 11405659  0.76
2001 Lichtman AH, Poklis JL, Poklis A, Wilson DM, Martin BR. The pharmacological activity of inhalation exposure to marijuana smoke in mice. Drug and Alcohol Dependence. 63: 107-16. PMID 11376914 DOI: 10.1016/S0376-8716(00)00205-2  1
2001 Selley DE, Rorrer WK, Breivogel CS, Zimmer AM, Zimmer A, Martin BR, Sim-Selley LJ. Agonist efficacy and receptor efficiency in heterozygous CB1 knockout mice: relationship of reduced CB1 receptor density to G-protein activation. Journal of Neurochemistry. 77: 1048-57. PMID 11359870  0.68
2001 Wiley JL, Jefferson RG, Grier MC, Mahadevan A, Razdan RK, Martin BR. Novel pyrazole cannabinoids: insights into CB(1) receptor recognition and activation. The Journal of Pharmacology and Experimental Therapeutics. 296: 1013-22. PMID 11181936  1
2001 Di Marzo V, Bisogno T, De Petrocellis L, Brandi I, Jefferson RG, Winckler RL, Davis JB, Dasse O, Mahadevan A, Razdan RK, Martin BR. Highly selective CB(1) cannabinoid receptor ligands and novel CB(1)/VR(1) vanilloid receptor "hybrid" ligands. Biochemical and Biophysical Research Communications. 281: 444-51. PMID 11181068 DOI: 10.1006/bbrc.2001.4354  0.72
2001 Griffin G, Williams S, Aung MM, Razdan RK, Martin BR, Abood ME. Separation of cannabinoid receptor affinity and efficacy in delta-8-tetrahydrocannabinol side-chain analogues. British Journal of Pharmacology. 132: 525-35. PMID 11159703 DOI: 10.1038/sj.bjp.0703827  1
2000 Ferretti G, Dukat M, Giannella M, Piergentili A, Pigini M, Quaglia W, Damaj MI, Martin BR, Glennon RA. Chain-lengthened and imidazoline analogues of nicotine. Bioorganic & Medicinal Chemistry Letters. 10: 2665-8. PMID 11128647 DOI: 10.1016/S0960-894X(00)00541-2  1
2000 Di Marzo V, Breivogel CS, Tao Q, Bridgen DT, Razdan RK, Zimmer AM, Zimmer A, Martin BR. Levels, metabolism, and pharmacological activity of anandamide in CB(1) cannabinoid receptor knockout mice: evidence for non-CB(1), non-CB(2) receptor-mediated actions of anandamide in mouse brain. Journal of Neurochemistry. 75: 2434-44. PMID 11080195  0.88
2000 Damaj MI, Meyer EM, Martin BR. The antinociceptive effects of alpha7 nicotinic agonists in an acute pain model. Neuropharmacology. 39: 2785-91. PMID 11044748 DOI: 10.1016/S0028-3908(00)00139-8  1
2000 Di Marzo V, Breivogel C, Bisogno T, Melck D, Patrick G, Tao Q, Szallasi A, Razdan RK, Martin BR. Neurobehavioral activity in mice of N-vanillyl-arachidonyl-amide. European Journal of Pharmacology. 406: 363-74. PMID 11040343  0.72
2000 Mahadevan A, Siegel C, Martin BR, Abood ME, Beletskaya I, Razdan RK. Novel cannabinol probes for CB1 and CB2 cannabinoid receptors. Journal of Medicinal Chemistry. 43: 3778-85. PMID 11020293 DOI: 10.1021/jm0001572  1
2000 Narahashi T, Fenster CP, Quick MW, Lester RA, Marszalec W, Aistrup GL, Sattelle DB, Martin BR, Levin ED. Symposium overview: mechanism of action of nicotine on neuronal acetylcholine receptors, from molecule to behavior. Toxicological Sciences : An Official Journal of the Society of Toxicology. 57: 193-202. PMID 11006350  1
2000 Slemmer JE, Martin BR, Damaj MI. Bupropion is a nicotinic antagonist. The Journal of Pharmacology and Experimental Therapeutics. 295: 321-7. PMID 10991997  0.76
2000 Wiley JL, Dewey MA, Jefferson RG, Winckler RL, Bridgen DT, Willoughby KA, Martin BR. Influence of phenylmethylsulfonyl fluoride on anandamide brain levels and pharmacological effects. Life Sciences. 67: 1573-83. PMID 10983852 DOI: 10.1016/S0024-3205(00)00749-9  1
2000 Martin BR, Beletskaya I, Patrick G, Jefferson R, Winckler R, Deutsch DG, Di Marzo V, Dasse O, Mahadevan A, Razdan RK. Cannabinoid properties of methylfluorophosphonate analogs. The Journal of Pharmacology and Experimental Therapeutics. 294: 1209-18. PMID 10945879  1
2000 Aung MM, Griffin G, Huffman JW, Wu M, Keel C, Yang B, Showalter VM, Abood ME, Martin BR. Influence of the N-1 alkyl chain length of cannabimimetic indoles upon CB(1) and CB(2) receptor binding. Drug and Alcohol Dependence. 60: 133-40. PMID 10940540 DOI: 10.1016/S0376-8716(99)00152-0  1
2000 Bass CE, Martin BR. Time course for the induction and maintenance of tolerance to Delta(9)-tetrahydrocannabinol in mice. Drug and Alcohol Dependence. 60: 113-9. PMID 10940538 DOI: 10.1016/S0376-8716(99)00150-7  1
2000 Lichtman AH, Peart J, Poklis JL, Bridgen DT, Razdan RK, Wilson DM, Poklis A, Meng Y, Byron PR, Martin BR. Pharmacological evaluation of aerosolized cannabinoids in mice. European Journal of Pharmacology. 399: 141-9. PMID 10884513 DOI: 10.1016/S0014-2999(00)00321-6  1
2000 Wiley JL, Patrick GS, Crocker PC, Saha B, Razdan RK, Martin BR. Antinociceptive effects of tetrahydrocannabinol side chain analogs: dependence upon route of administration. European Journal of Pharmacology. 397: 319-26. PMID 10844130 DOI: 10.1016/S0014-2999(00)00259-4  1
2000 Pertwee RG, Gibson TM, Stevenson LA, Ross RA, Banner WK, Saha B, Razdan RK, Martin BR. O-1057, a potent water-soluble cannabinoid receptor agonist with antinociceptive properties. British Journal of Pharmacology. 129: 1577-84. PMID 10780961 DOI: 10.1038/sj.bjp.0703245  1
2000 Huffman JW, Lu J, Dai D, Kitaygorodskiy A, Wiley JL, Martin BR. Synthesis and pharmacology of a hybrid cannabinoid. Bioorganic & Medicinal Chemistry. 8: 439-47. PMID 10722167 DOI: 10.1016/S0968-0896(99)00305-3  1
2000 Beardsley PM, Martin BR. Effects of the cannabinoid CB(1) receptor antagonist, SR141716A, after Delta(9)-tetrahydrocannabinol withdrawal. European Journal of Pharmacology. 387: 47-53. PMID 10633159 DOI: 10.1016/S0014-2999(99)00792-X  1
2000 Keimowitz AR, Martin BR, Razdan RK, Crocker PJ, Mascarella SW, Thomas BF. QSAR analysis of Delta(8)-THC analogues: relationship of side-chain conformation to cannabinoid receptor affinity and pharmacological potency. Journal of Medicinal Chemistry. 43: 59-70. PMID 10633038 DOI: 10.1021/jm9902281  1
1999 Huffman JW, Liddle J, Yu S, Aung MM, Abood ME, Wiley JL, Martin BR. 3-(1',1'-Dimethylbutyl)-1-deoxy-delta8-THC and related compounds: synthesis of selective ligands for the CB2 receptor. Bioorganic & Medicinal Chemistry. 7: 2905-14. PMID 10658595 DOI: 10.1016/S0968-0896(99)00219-9  1
1999 Járai Z, Wagner JA, Varga K, Lake KD, Compton DR, Martin BR, Zimmer AM, Bonner TI, Buckley NE, Mezey E, Razdan RK, Zimmer A, Kunos G. Cannabinoid-induced mesenteric vasodilation through an endothelial site distinct from CB1 or CB2 receptors. Proceedings of the National Academy of Sciences of the United States of America. 96: 14136-41. PMID 10570211 DOI: 10.1073/pnas.96.24.14136  0.72
1999 Damaj MI, Glassco W, Dukat M, Martin BR. Pharmacological characterization of nicotine-induced seizures in mice. The Journal of Pharmacology and Experimental Therapeutics. 291: 1284-91. PMID 10565853  0.76
1999 Wiley JL, Martin BR. Effects of SR141716A on diazepam substitution for delta9-tetrahydrocannabinol in rat drug discrimination. Pharmacology, Biochemistry, and Behavior. 64: 519-22. PMID 10548265 DOI: 10.1016/S0091-3057(99)00130-6  1
1999 Griffin G, Wray EJ, Martin BR, Abood ME. Cannabinoid agonists and antagonists discriminated by receptor binding in rat cerebellum. British Journal of Pharmacology. 128: 684-8. PMID 10516649 DOI: 10.1038/sj.bjp.0702806  1
1999 Damaj MI, Glassco W, Aceto MD, Martin BR. Antinociceptive and pharmacological effects of metanicotine, a selective nicotinic agonist. The Journal of Pharmacology and Experimental Therapeutics. 291: 390-8. PMID 10490929  0.76
1999 Martin BR, Mechoulam R, Razdan RK. Discovery and characterization of endogenous cannabinoids. Life Sciences. 65: 573-95. PMID 10462059 DOI: 10.1016/S0024-3205(99)00281-7  1
1999 Martin BR, Jefferson R, Winckler R, Wiley JL, Huffman JW, Crocker PJ, Saha B, Razdan RK. Manipulation of the tetrahydrocannabinol side chain delineates agonists, partial agonists, and antagonists. The Journal of Pharmacology and Experimental Therapeutics. 290: 1065-79. PMID 10454479  1
1999 Griffin G, Wray EJ, Tao Q, McAllister SD, Rorrer WK, Aung MM, Martin BR, Abood ME. Evaluation of the cannabinoid CB2 receptor-selective antagonist, SR144528: further evidence for cannabinoid CB2 receptor absence in the rat central nervous system. European Journal of Pharmacology. 377: 117-25. PMID 10448934 DOI: 10.1016/S0014-2999(99)00402-1  1
1999 Ng EW, Aung MM, Abood ME, Martin BR, Razdan RK. Unique analogues of anandamide: arachidonyl ethers and carbamates and norarachidonyl carbamates and ureas. Journal of Medicinal Chemistry. 42: 1975-81. PMID 10354405 DOI: 10.1021/jm980711w  1
1999 Damaj MI, Slemmer JE, Carroll FI, Martin BR. Pharmacological characterization of nicotine's interaction with cocaine and cocaine analogs. The Journal of Pharmacology and Experimental Therapeutics. 289: 1229-36. PMID 10336510  0.76
1999 Griffin G, Wray EJ, Rorrer WK, Crocker PJ, Ryan WJ, Saha B, Razdan RK, Martin BR, Abood ME. An investigation into the structural determinants of cannabinoid receptor ligand efficacy. British Journal of Pharmacology. 126: 1575-84. PMID 10323589 DOI: 10.1038/sj.bjp.0702469  1
1999 Meng Y, Dukat M, Bridgen DT, Martin BR, Lichtman AH. Pharmacological effects of methamphetamine and other stimulants via inhalation exposure. Drug and Alcohol Dependence. 53: 111-20. PMID 10080037 DOI: 10.1016/S0376-8716(98)00120-3  1
1998 Martin BR, Lichtman AH. Cannabinoid transmission and pain perception. Neurobiology of Disease. 5: 447-61. PMID 9974177 DOI: 10.1006/nbdi.1998.0218  1
1998 Huffman JW, Liddle J, Duncan SG, Yu S, Martin BR, Wiley JL. Synthesis and pharmacology of the isomeric methylheptyl-delta8-tetrahydrocannabinols. Bioorganic & Medicinal Chemistry. 6: 2383-96. PMID 9925296 DOI: 10.1016/S0968-0896(98)80014-X  1
1998 Liddle J, Huffman JW, Wiley JL, Martin BR. Enantioselective synthesis and pharmacology of 11-hydroxy-(1'S,2'R)-dimethylheptyl-delta 8-THC. Bioorganic & Medicinal Chemistry Letters. 8: 2223-6. PMID 9873517 DOI: 10.1016/S0960-894X(98)00385-0  1
1998 Aceto MD, Scates SM, Razdan RK, Martin BR. Anandamide, an endogenous cannabinoid, has a very low physical dependence potential. The Journal of Pharmacology and Experimental Therapeutics. 287: 598-605. PMID 9808686  0.72
1998 Lichtman AH, Wiley JL, LaVecchia KL, Neviaser ST, Arthur DB, Wilson DM, Martin BR. Effects of SR 141716A after acute or chronic cannabinoid administration in dogs. European Journal of Pharmacology. 357: 139-48. PMID 9797029 DOI: 10.1016/S0014-2999(98)00558-5  1
1998 Singer M, Ryan WJ, Saha B, Martin BR, Razdan RK. Potent cyano and carboxamido side-chain analogues of 1', 1'-dimethyl-delta8-tetrahydrocannabinol. Journal of Medicinal Chemistry. 41: 4400-7. PMID 9784115 DOI: 10.1021/jm9803875  1
1998 Wiley JL, Ryan WJ, Razdan RK, Martin BR. Evaluation of cannabimimetic effects of structural analogs of anandamide in rats. European Journal of Pharmacology. 355: 113-8. PMID 9760024 DOI: 10.1016/S0014-2999(98)00502-0  1
1998 Cook SA, Lowe JA, Martin BR. CB1 receptor antagonist precipitates withdrawal in mice exposed to Delta9-tetrahydrocannabinol. The Journal of Pharmacology and Experimental Therapeutics. 285: 1150-6. PMID 9618417  0.48
1998 Wiley JL, Compton DR, Dai D, Lainton JA, Phillips M, Huffman JW, Martin BR. Structure-activity relationships of indole- and pyrrole-derived cannabinoids. The Journal of Pharmacology and Experimental Therapeutics. 285: 995-1004. PMID 9618400  1
1998 Griffin G, Atkinson PJ, Showalter VM, Martin BR, Abood ME. Evaluation of cannabinoid receptor agonists and antagonists using the guanosine-5'-O-(3-[35S]thio)-triphosphate binding assay in rat cerebellar membranes. The Journal of Pharmacology and Experimental Therapeutics. 285: 553-60. PMID 9580597  1
1998 Adams IB, Compton DR, Martin BR. Assessment of anandamide interaction with the cannabinoid brain receptor: SR 141716A antagonism studies in mice and autoradiographic analysis of receptor binding in rat brain. The Journal of Pharmacology and Experimental Therapeutics. 284: 1209-17. PMID 9495885  0.56
1998 Damaj MI, Fei-Yin M, Dukat M, Glassco W, Glennon RA, Martin BR. Antinociceptive responses to nicotinic acetylcholine receptor ligands after systemic and intrathecal administration in mice. The Journal of Pharmacology and Experimental Therapeutics. 284: 1058-65. PMID 9495867  1
1997 Wiley JL, Golden KM, Ryan WJ, Balster RL, Razdan RK, Martin BR. Evaluation of cannabimimetic discriminative stimulus effects of anandamide and methylated fluoroanandamide in rhesus monkeys. Pharmacology, Biochemistry, and Behavior. 58: 1139-43. PMID 9408225 DOI: 10.1016/S0091-3057(97)00327-4  1
1997 Compton DR, Martin BR. The effect of the enzyme inhibitor phenylmethylsulfonyl fluoride on the pharmacological effect of anandamide in the mouse model of cannabimimetic activity. The Journal of Pharmacology and Experimental Therapeutics. 283: 1138-43. PMID 9399986  0.56
1997 Wagner JA, Varga K, Ellis EF, Rzigalinski BA, Martin BR, Kunos G. Activation of peripheral CB1 cannabinoid receptors in haemorrhagic shock. Nature. 390: 518-21. PMID 9394002 DOI: 10.1038/37371  1
1997 Reggio PH, Wang T, Brown AE, Fleming DN, Seltzman HH, Griffin G, Pertwee RG, Compton DR, Abood ME, Martin BR. Importance of the C-1 substituent in classical cannabinoids to CB2 receptor selectivity: synthesis and characterization of a series of O,2-propano-delta 8-tetrahydrocannabinol analogs. Journal of Medicinal Chemistry. 40: 3312-8. PMID 9379452 DOI: 10.1021/jm970136g  0.56
1997 Seltzman HH, Fleming DN, Thomas BF, Gilliam AF, McCallion DS, Pertwee RG, Compton DR, Martin BR. Synthesis and pharmacological comparison of dimethylheptyl and pentyl analogs of anandamide. Journal of Medicinal Chemistry. 40: 3626-34. PMID 9357529 DOI: 10.1021/jm9702950  1
1997 Ryan WJ, Banner WK, Wiley JL, Martin BR, Razdan RK. Potent anandamide analogs: the effect of changing the length and branching of the end pentyl chain. Journal of Medicinal Chemistry. 40: 3617-25. PMID 9357528 DOI: 10.1021/jm970212f  1
1997 Damaj MI, Glassco W, Marks MJ, Slobe B, James JR, May EL, Rosecrans JA, Collins AC, Martin BR. Pharmacological investigation of (+)- and (-)-cis-2,3,3a,4,5,9b-hexahydro-1-methyl-1H-pyrrolo-[3,2-h]isoq uinoline, a bridged-nicotine analog. The Journal of Pharmacology and Experimental Therapeutics. 282: 1425-34. PMID 9316856  1
1997 Dutta AK, Ryan W, Thomas BF, Singer M, Compton DR, Martin BR, Razdan RK. Synthesis, pharmacology, and molecular modeling of novel 4-alkyloxy indole derivatives related to cannabimimetic aminoalkyl indoles (AAIs). Bioorganic & Medicinal Chemistry. 5: 1591-600. PMID 9313864 DOI: 10.1016/S0968-0896(97)00111-9  1
1997 Meng Y, Lichtman AH, Bridgen DT, Martin BR. Inhalation studies with drugs of abuse. Nida Research Monograph. 173: 201-24. PMID 9260190  1
1997 Damaj MI, Patrick GS, Creasy KR, Martin BR. Pharmacology of lobeline, a nicotinic receptor ligand. The Journal of Pharmacology and Experimental Therapeutics. 282: 410-9. PMID 9223582  0.76
1997 Willoughby KA, Moore SF, Martin BR, Ellis EF. The biodisposition and metabolism of anandamide in mice. The Journal of Pharmacology and Experimental Therapeutics. 282: 243-7. PMID 9223560  1
1997 Lake KD, Compton DR, Varga K, Martin BR, Kunos G. Cannabinoid-induced hypotension and bradycardia in rats mediated by CB1-like cannabinoid receptors. The Journal of Pharmacology and Experimental Therapeutics. 281: 1030-7. PMID 9190833  0.56
1997 Budney AJ, Kandel DB, Cherek DR, Martin BR, Stephens RS, Roffman R. College on problems of drug dependence meeting, Puerto Rico (June 1996) marijuana use and dependence. Drug and Alcohol Dependence. 45: 1-11. PMID 9179501 DOI: 10.1016/S0376-8716(97)01351-3  1
1997 Lichtman AH, Martin BR. The selective cannabinoid antagonist SR 141716A blocks cannabinoid-induced antinociception in rats. Pharmacology, Biochemistry, and Behavior. 57: 7-12. PMID 9164547  1
1996 Wiley JL, Compton DR, Gordon PM, Siegel C, Singer M, Dutta A, Lichtman AH, Balster RL, Razdan RK, Martin BR. Evaluation of agonist-antagonist properties of nitrogen mustard and cyano derivatives of delta 8-tetrahydrocannabinol. Neuropharmacology. 35: 1793-804. PMID 9076759 DOI: 10.1016/S0028-3908(96)00120-7  1
1996 Pertwee RG, Fernando SR, Griffin G, Ryan W, Razdan RK, Compton DR, Martin BR. Agonist-antagonist characterization of 6'-cyanohex-2'-yne-delta 8-tetrahydrocannabinol in two isolated tissue preparations. European Journal of Pharmacology. 315: 195-201. PMID 8960884 DOI: 10.1016/S0014-2999(96)00631-0  0.72
1996 Meng Y, Lichtman AH, Bridgen DT, Martin BR. Pharmacological potency and biodisposition of phencyclidine via inhalation exposure in mice. Drug and Alcohol Dependence. 43: 13-22. PMID 8957139 DOI: 10.1016/S0376-8716(96)01284-7  1
1996 Lichtman AH, Meng Y, Martin BR. Inhalation exposure to volatilized opioids produces antinociception in mice. The Journal of Pharmacology and Experimental Therapeutics. 279: 69-76. PMID 8858977  1
1996 Lichtman AH, Martin BR. Delta 9-tetrahydrocannabinol impairs spatial memory through a cannabinoid receptor mechanism. Psychopharmacology. 126: 125-31. PMID 8856831  1
1996 Lichtman AH, Cook SA, Martin BR. Investigation of brain sites mediating cannabinoid-induced antinociception in rats: evidence supporting periaqueductal gray involvement. The Journal of Pharmacology and Experimental Therapeutics. 276: 585-93. PMID 8632325  1
1995 Lichtman AH, Dimen KR, Martin BR. Systemic or intrahippocampal cannabinoid administration impairs spatial memory in rats. Psychopharmacology. 119: 282-90. PMID 7675962  1
1995 Lichtman AH, Sathe P, Dimen KR, Martin BR. Acute tolerance to the cardiovascular effects of volatilized cocaine free base in rats. Drug and Alcohol Dependence. 38: 247-54. PMID 7555625  1
1990 Compton DR, Dewey WL, Martin BR. Cannabis dependence and tolerance production. Advances in Alcohol & Substance Abuse. 9: 129-47. PMID 2165734 DOI: 10.1300/J251v09n01_08  1
1987 Estrada U, Brase DA, Martin BR, Dewey WL. Cardiovascular effects of delta 9- and delta 9(11)-tetrahydrocannabinol and their interaction with epinephrine. Life Sciences. 41: 79-87. PMID 3037218 DOI: 10.1016/0024-3205(87)90559-5  1
1986 Aceto MD, Bagley RS, Dewey WL, Fu TC, Martin BR. The spinal cord as a major site for the antinociceptive action of nicotine in the rat. Neuropharmacology. 25: 1031-6. PMID 3774124 DOI: 10.1016/0028-3908(86)90198-X  1
1985 Kachur JF, Rosemond R, Welch S, Bowman ER, Martin BR, Brase DA, Dewey WL. Comparison of the ability of opioid analgesics to increase endogenous opioid-like activity in the cerebrospinal fluid of rabbits. Life Sciences. 37: 2549-55. PMID 4079662 DOI: 10.1016/0024-3205(85)90613-7  1
1985 Jorapur VS, Khalil ZH, Duffley RP, Razdan RK, Martin BR, Harris LS, Dewey WL. Hashish: synthesis and central nervous system activity of some novel analogues of cannabidiol and oxepin derivatives of delta 9-tetrahydrocannabinol. Journal of Medicinal Chemistry. 28: 783-7. PMID 2989518  1
1984 Robertson LR, Duffley RP, Razdan RK, Martin BR, Harris LS, Dewey WL. Synthesis and pharmacological activity of some 9-substituted delta 8-tetrahydrocannabinol analogues. Journal of Medicinal Chemistry. 27: 550-2. PMID 6323713  1
1984 Shook JE, Kallman MJ, Martin BR, Dewey WL. Characterization of the interaction of pentazocine and tripelennamine: drug discrimination and mu-receptor binding assay. Pharmacology, Biochemistry, and Behavior. 21: 877-81. PMID 6097919  1
1984 Martin BR, Kallman MJ, Kaempf GF, Harris LS, Dewey WL, Razdan RK. Pharmacological potency of R- and S-3'-hydroxy-delta 9-tetrahydrocannabinol: additional structural requirement for cannabinoid activity. Pharmacology, Biochemistry, and Behavior. 21: 61-5. PMID 6087379 DOI: 10.1016/0091-3057(84)90131-X  1
1982 Dewey WL, Bowman E, Jones D, Kachur J, Rosemond R, Welch S, Martin BR. The appearance of endogenous opiates in cerebrospinal fluid following opiate injection in various animal species. Life Sciences. 31: 1741-3. PMID 7154834 DOI: 10.1016/0024-3205(82)90199-0  1
1982 Handrick GR, Duffley RP, Lambert G, Murphy JG, Dalzell HC, Howes JF, Razdan RK, Martin BR, Harris LS, Dewey WL. 3'-Hydroxy- and (+/-)-3',11-dihydroxy-delta 9-tetrahydrocannabinol: biologically active metabolites of delta 9-tetrahydrocannabinol. Journal of Medicinal Chemistry. 25: 1447-50. PMID 6296389  1
1982 Dewey WL, Fu TC, Ohlsson A, Bowman E, Martin BR. Evidence for the release of endogenous opiates by morphine. Nida Research Monograph. 41: 60-6. PMID 6289120  1
1982 Ohlsson AE, Fu TC, Jones D, Martin BR, Dewey WL. Distribution of radioactivity in the spinal cord after intracerebroventricular and intravenous injection of radiolabeled opioid peptides in mice. The Journal of Pharmacology and Experimental Therapeutics. 221: 362-7. PMID 6281413  1
1981 Martin BR, Balster RL, Razdan RK, Harris LS, Dewey WL. Behavioral comparisons of the stereoisomers of tetrahydrocannabinols. Life Sciences. 29: 565-74. PMID 6268916 DOI: 10.1016/0024-3205(81)90434-3  1
1980 Alozie SO, Martin BR, Harris LS, Dewey WL. 3H-delta 9-Tetrahydrocannabinol, 3H-cannabinol and 3H-cannabidiol: penetration and regional distribution in rat brain. Pharmacology, Biochemistry, and Behavior. 12: 217-21. PMID 6246544 DOI: 10.1016/0091-3057(80)90359-7  1
1979 Wilson RS, Martin BR, Dewey WL. Some 11-substituted tetrahydrocannabinols. Synthesis and comparison with the potent cannabinoid metabolites 11-hydroxytetrahydrocannabinols. Journal of Medicinal Chemistry. 22: 879-82. PMID 448686  1
1979 Aceto MD, Martin BR, Uwaydah IM, May EL, Harris LS, Izazola-Conde C, Dewey WL, Bradshaw TJ, Vincek WC. Optically pure (+)-nicotine from (+/-)-nicotine and biological comparisons with (-)-nicotine. Journal of Medicinal Chemistry. 22: 174-7. PMID 423195  1
1978 Martin BR, Montgomery J, Dewey WL, Harris LS. Alterations in the pharmacokinetics of 3H-delta9-tetrahydrocannabinol in mice by bacterial endotoxin. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 6: 282-7. PMID 26549  1
1977 Martin BR, Dewey WL, Harris LS, Beckner JS. 3H-delta9-tetrahydrocannabinol distribution in pregnant dogs and their fetuses. Research Communications in Chemical Pathology and Pharmacology. 17: 457-70. PMID 897339  1
1977 Adams MD, Earnhardt JT, Martin BR, Harris LS, Dewey WL, Razdan RK. A cannabinoid with cardiovascular activity but no overt behavioral effects. Experientia. 33: 1204-5. PMID 891878  1
1977 Martin BR, Dewey WL, Aceto MD, Adams MD, Earnhardt JT, Carney JM. A potent antinociceptive cannabinoid which lacks opiate substitution properties in monkeys. Research Communications in Chemical Pathology and Pharmacology. 16: 187-90. PMID 402685  1
1977 Martin BR, Dewey WL, Chau-Pham T, Prnage AJ. Interactions of thyrotropin releasing hormone and morphine sulfate in rodents. Life Sciences. 20: 715-22. PMID 402526  1
1976 Martin BR, Dewey WL, Harris LS, Beckner JS. 3H-delta9-tetrahydrocannabinol tissue and subcellular distribution in the central nervous system and tissue distribution in peripheral organs of tolerant and nontolerant dogs. The Journal of Pharmacology and Experimental Therapeutics. 196: 128-44. PMID 1246007  1
1975 Martin BR, Dewey WL, Harris LS, Beckner J. Marihuana-like activity of new synthetic tetrahydrocannabinols. Pharmacology, Biochemistry, and Behavior. 3: 849-53. PMID 1208625 DOI: 10.1016/S0090-3752(76)80023-3  1
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