David A. Eisner - Publications

Affiliations: 
University of Manchester, Manchester, England, United Kingdom 
Area:
cardiac muscle,cellular electrophysiology

231 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Caldwell JL, Clarke JD, Smith CER, Pinali C, Quinn CJ, Pearman CM, Adomaviciene A, Radcliffe EJ, Watkins AE, Horn MA, Bode EF, Madders GWP, Eisner M, Eisner DA, Trafford AW, et al. Restoring Atrial T-Tubules Augments Systolic Ca Upon Recovery From Heart Failure. Circulation Research. PMID 39140440 DOI: 10.1161/CIRCRESAHA.124.324601  0.807
2023 Eisner D, Neher E, Taschenberger H, Smith G. Physiology of intracellular calcium buffering. Physiological Reviews. PMID 37326298 DOI: 10.1152/physrev.00042.2022  0.613
2022 Smith CER, Pinali C, Eisner DA, Trafford AW, Dibb KM. Enhanced calcium release at specialised surface sites compensates for reduced t-tubule density in neonatal sheep atrial myocytes. Journal of Molecular and Cellular Cardiology. PMID 36038009 DOI: 10.1016/j.yjmcc.2022.08.360  0.681
2022 Hutchings DC, Madders GWP, Niort BC, Bode EF, Waddell CA, Woods LS, Dibb KM, Eisner DA, Trafford AW. Interaction of background Ca influx, sarcoplasmic reticulum threshold and heart failure in determining propensity for Ca waves in sheep heart. The Journal of Physiology. PMID 35233776 DOI: 10.1113/JP282168  0.748
2021 Hutchings DC, Pearman CM, Madders GW, Woods LS, Eisner DA, Dibb KM, Trafford AW. PDE5 Inhibition Suppresses Ventricular Arrhythmias by Reducing SR Ca Content. Circulation Research. PMID 34247494 DOI: 10.1161/CIRCRESAHA.121.318473  0.767
2020 Kistamás K, Veress R, Horváth B, Bányász T, Nánási PP, Eisner DA. Calcium Handling Defects and Cardiac Arrhythmia Syndromes. Frontiers in Pharmacology. 11: 72. PMID 32161540 DOI: 10.3389/Fphar.2020.00072  0.558
2020 Eisner DA, Caldwell JL, Trafford AW, Hutchings DC. The Control of Diastolic Calcium in the Heart: Basic Mechanisms and Functional Implications. Circulation Research. 126: 395-412. PMID 31999537 DOI: 10.1161/Circresaha.119.315891  0.734
2020 Radcliffe EJ, Pearman CM, Watkins A, Lawless M, Kirkwood GJ, Saxton SN, Eisner DA, Trafford AW. Chronic vagal nerve stimulation has no effect on tachycardia-induced heart failure progression or excitation-contraction coupling. Physiological Reports. 8: e14321. PMID 31961064 DOI: 10.14814/Phy2.14321  0.593
2020 Madders G, Denham N, Pearman C, Hutchings D, Woods L, Waddell C, Smithen M, Trafford A, Eisner D, Dibb K. Increased alternans susceptibility in heart failure is linked to action potential morphology Journal of Molecular and Cellular Cardiology. 140: 27-28. DOI: 10.1016/J.Yjmcc.2019.11.063  0.557
2019 Greenstein AS, Kadir SZAS, Csato V, Sugden SA, Baylie RA, Eisner DA, Nelson MT. Disruption of Pressure-Induced Ca Spark Vasoregulation of Resistance Arteries, Rather Than Endothelial Dysfunction, Underlies Obesity-Related Hypertension. Hypertension (Dallas, Tex. : 1979). HYPERTENSIONAHA11913. PMID 31865779 DOI: 10.1161/Hypertensionaha.119.13540  0.477
2019 Smith GL, Eisner DA. Calcium Buffering in the Heart in Health and Disease. Circulation. 139: 2358-2371. PMID 31082292 DOI: 10.1161/Circulationaha.118.039329  0.59
2019 Lawless M, Caldwell JL, Radcliffe EJ, Smith CER, Madders GWP, Hutchings DC, Woods LS, Church SJ, Unwin RD, Kirkwood GJ, Becker LK, Pearman CM, Taylor RF, Eisner DA, Dibb KM, et al. Phosphodiesterase 5 inhibition improves contractile function and restores transverse tubule loss and catecholamine responsiveness in heart failure. Scientific Reports. 9: 6801. PMID 31043634 DOI: 10.1038/S41598-019-42592-1  0.56
2018 Pearman CM, Madders GWP, Radcliffe EJ, Kirkwood GJ, Lawless M, Watkins A, Smith CER, Trafford AW, Eisner DA, Dibb KM. Increased Vulnerability to Atrial Fibrillation Is Associated With Increased Susceptibility to Alternans in Old Sheep. Journal of the American Heart Association. 7: e009972. PMID 30520673 DOI: 10.1161/Jaha.118.009972  0.663
2018 Denham NC, Pearman CM, Caldwell JL, Madders GWP, Eisner DA, Trafford AW, Dibb KM. Calcium in the Pathophysiology of Atrial Fibrillation and Heart Failure. Frontiers in Physiology. 9: 1380. PMID 30337881 DOI: 10.3389/Fphys.2018.01380  0.582
2018 Eisner DA. Ups and downs of calcium in the heart. The Journal of Physiology. 596: 19-30. PMID 29071725 DOI: 10.1113/Jp275130  0.704
2018 Radcliffe E, Sun J, Aponte A, Eisner D, Murphy M, Galli G, Murphy E, Trafford A. Protein S-nitrosylation inhibits respiration in the failing heart Journal of Molecular and Cellular Cardiology. 124: 101. DOI: 10.1016/J.Yjmcc.2018.07.058  0.542
2018 Madders G, Woods L, Hutchings D, Waddell C, Denham N, Trafford A, Eisner D, Dibb K. Susceptibility to atrial alternans; a role for transverse (t)-tubule loss in heart failure (HF)? Journal of Molecular and Cellular Cardiology. 120: 50. DOI: 10.1016/J.Yjmcc.2018.05.147  0.547
2018 Hutchings D, Pearman C, Madders G, Woods L, Dibb K, Eisner D, Trafford A. Phosphodiesterase-5 inhibition with sildenafil suppresses triggered ventricular arrhythmias and calcium waves via reduced sarcoplasmic reticulum content in the large mammal Journal of Molecular and Cellular Cardiology. 120: 37. DOI: 10.1016/J.Yjmcc.2018.05.112  0.587
2017 Clarke JD, Caldwell JL, Pearman CM, Eisner DA, Trafford AW, Dibb KM. Increased Ca buffering underpins remodelling of Ca(2+) handling in old sheep atrial myocytes. The Journal of Physiology. PMID 28752958 DOI: 10.1113/Jp274053  0.786
2017 Eisner DA, Caldwell JL, Kistamás K, Trafford AW. Calcium and Excitation-Contraction Coupling in the Heart. Circulation Research. 121: 181-195. PMID 28684623 DOI: 10.1161/Circresaha.117.310230  0.797
2017 Sankaranarayanan R, Kistamas K, Greensmith DJ, Venetucci LA, Eisner DA. Systolic [Ca(2+) ]i regulates diastolic levels in rat ventricular myocytes. The Journal of Physiology. PMID 28617952 DOI: 10.1113/Jp274366  0.868
2017 Radcliffe E, Sun J, Aponte A, Eisner D, Murphy E, Trafford A. 198 Heart failure increases mitochondrial s-nitrosylation Heart. 103: A134-A135. DOI: 10.1136/Heartjnl-2017-311726.196  0.564
2017 Hutchings D, Dibb K, Pearman C, Madders G, Woods L, Eisner D, Trafford A. 179 Phosphodiesterase-5 inhibition with sildenafil suppresses calcium waves by reducing sarcoplasmic reticulum content Heart. 103: A124.1-A124. DOI: 10.1136/Heartjnl-2017-311726.177  0.711
2017 Caldwell J, Taylor R, Eisner D, Dibb K, Trafford A. 171 Amphiphysin ii (bin1) driven transverse tubule formation in cardiac muscle Heart. 103: A120.1-A120. DOI: 10.1136/Heartjnl-2017-311726.169  0.61
2017 Hutchings D, Dibb K, Eisner D, Trafford A. Effects of phosphodiesterase-5 inhibition with sildenafil on calcium waves in cardiac myocytes The Lancet. 389: S50. DOI: 10.1016/S0140-6736(17)30446-4  0.717
2016 Sag C, Ward A, Crocini C, Watkins A, Hayer S, Wang Y, Rex N, Wagner S, De Franceschi L, Vinchi F, Cimino J, Petrillo S, Silengo L, Altruda F, Maier LS, ... ... Eisner D, et al. Late Breaking Science502Hemopexin counteracts systolic dysfunction induced by heme overload503Inhibition of NF-kappa B suppressed inflammation induced by acute shear stress in endothelial cells: Implications for vein graft failure504Optical treatment of cardiac arrhythmias505Tachypacing-induced heart failure: a metabolomic investigation506Characterization of early left ventricle dysfunction in a relevant experimental model for human rheumatoid arthritis507Circadian rhythm in heart rate is due to an intrinsic circadian clock in the sinus node Cardiovascular Research. 111: S90-S91. DOI: 10.1093/Cvr/Cvw142  0.548
2016 Smith CE, Eisner DA, Trafford AW, Dibb KM. Postnatal Development of T-Tubules in Sheep Atrial Myocytes Biophysical Journal. 110: 598a. DOI: 10.1016/J.Bpj.2015.11.3194  0.56
2015 Sankaranarayanan R, Li Y, Greensmith DJ, Eisner DA, Venetucci L. Biphasic decay of the Ca transient results from increased sarcoplasmic reticulum Ca leak. The Journal of Physiology. PMID 26537441 DOI: 10.1113/Jp271473  0.859
2015 Miller L, Greensmith DJ, Sankaranarayanan R, O'Neill SC, Eisner DA. The effect of 2,5-di-(tert-butyl)-1,4-benzohydroquinone (TBQ) on intracellular Ca(2+) handling in rat ventricular myocytes. Cell Calcium. PMID 26120055 DOI: 10.1016/J.Ceca.2015.05.002  0.84
2015 Dibb K, Trafford A, Zhang H, Eisner D. A model model: a commentary on DiFrancesco and Noble (1985) 'A model of cardiac electrical activity incorporating ionic pumps and concentration changes'. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 370. PMID 25750236 DOI: 10.1098/Rstb.2014.0316  0.554
2015 Clarke JD, Caldwell JL, Horn MA, Bode EF, Richards MA, Hall MC, Graham HK, Briston SJ, Greensmith DJ, Eisner DA, Dibb KM, Trafford AW. Perturbed atrial calcium handling in an ovine model of heart failure: potential roles for reductions in the L-type calcium current. Journal of Molecular and Cellular Cardiology. 79: 169-79. PMID 25463272 DOI: 10.1016/J.Yjmcc.2014.11.017  0.885
2014 Caldwell JL, Smith CE, Taylor RF, Kitmitto A, Eisner DA, Dibb KM, Trafford AW. Dependence of cardiac transverse tubules on the BAR domain protein amphiphysin II (BIN-1). Circulation Research. 115: 986-96. PMID 25332206 DOI: 10.1161/Circresaha.116.303448  0.562
2014 Briston SJ, Dibb KM, Solaro RJ, Eisner DA, Trafford AW. Balanced changes in Ca buffering by SERCA and troponin contribute to Ca handling during β-adrenergic stimulation in cardiac myocytes. Cardiovascular Research. 104: 347-54. PMID 25183792 DOI: 10.1093/Cvr/Cvu201  0.784
2014 Eisner D. Calcium in the heart: from physiology to disease. Experimental Physiology. 99: 1273-82. PMID 25128325 DOI: 10.1113/expphysiol.2013.077305  0.648
2014 Greensmith DJ, Galli GL, Trafford AW, Eisner DA. Direct measurements of SR free Ca reveal the mechanism underlying the transient effects of RyR potentiation under physiological conditions. Cardiovascular Research. 103: 554-63. PMID 24947416 DOI: 10.1093/Cvr/Cvu158  0.888
2014 Pearman C, Trafford A, Eisner D, Dibb K. 218 Action Potential Alternans in the Ageing Ovine Atria Heart. 100: A119-A120. DOI: 10.1136/Heartjnl-2014-306118.218  0.549
2014 Eisner D. Calcium in the heart: From physiology to disease Experimental Physiology. 99: 1273-1282. DOI: 10.1113/Expphysiol.2013.077305  0.705
2014 Sankaranarayanan R, Li Y, Venetucci L, Eisner D. Effect of reduction in ryanodine receptor calcium leak on arrhythmogenesis in rat ventricular myocytes The Lancet. 383: S93. DOI: 10.1016/S0140-6736(14)60356-1  0.369
2013 Eisner D, Caldwell J, Trafford A. Sarcoplasmic reticulum Ca-ATPase and heart failure 20 years later. Circulation Research. 113: 958-61. PMID 24071456 DOI: 10.1161/Circresaha.113.302187  0.702
2013 Venetucci L, Sankaranarayanan R, Eisner DA. A tale of two leaks. Circulation. 128: 941-3. PMID 23877258 DOI: 10.1161/Circulationaha.113.004713  0.702
2013 Borysova L, Wray S, Eisner DA, Burdyga T. How calcium signals in myocytes and pericytes are integrated across in situ microvascular networks and control microvascular tone. Cell Calcium. 54: 163-74. PMID 23867002 DOI: 10.1016/J.Ceca.2013.06.001  0.739
2013 Lederer WJ, Bers DM, Eisner DA. Calcium signaling in heart: multiscale, diverse, rapid, local, and remarkable. Journal of Molecular and Cellular Cardiology. 58: 3-4. PMID 23500389 DOI: 10.1016/J.Yjmcc.2013.03.003  0.32
2013 Trafford AW, Clarke JD, Richards MA, Eisner DA, Dibb KM. Calcium signalling microdomains and the t-tubular system in atrial mycoytes: potential roles in cardiac disease and arrhythmias. Cardiovascular Research. 98: 192-203. PMID 23386275 DOI: 10.1093/Cvr/Cvt018  0.784
2013 Eisner D, Bode E, Venetucci L, Trafford A. Calcium flux balance in the heart. Journal of Molecular and Cellular Cardiology. 58: 110-7. PMID 23220128 DOI: 10.1016/J.Yjmcc.2012.11.017  0.801
2013 Johnson DM, Heijman J, Bode EF, Greensmith DJ, van der Linde H, Abi-Gerges N, Eisner DA, Trafford AW, Volders PG. Diastolic spontaneous calcium release from the sarcoplasmic reticulum increases beat-to-beat variability of repolarization in canine ventricular myocytes after β-adrenergic stimulation. Circulation Research. 112: 246-56. PMID 23149594 DOI: 10.1161/Circresaha.112.275735  0.87
2013 Dibb KM, Clarke JD, Eisner DA, Richards MA, Trafford AW. A functional role for transverse (t-) tubules in the atria. Journal of Molecular and Cellular Cardiology. 58: 84-91. PMID 23147188 DOI: 10.1016/J.Yjmcc.2012.11.001  0.658
2013 Cobb C, Walker R, Farrell K, Eisner D, Austin C, Holt C. 176 CONTRACTILITY IS INCREASED IN THORACIC AORTAE OF APOLIPOPROTEIN E KNOCK-OUT MICE PRIOR TO LESION DEVELOPMENT Heart. 99: A101.1-A101. DOI: 10.1136/Heartjnl-2013-304019.176  0.352
2013 Hutchings D, Lawless M, Eisner D, Trafford A. Effects of phosphodiesterase type 5A inhibition on intracellular calcium handling and its implications for cardioprotection and antiarrhythmogenesis The Lancet. 381. DOI: 10.1016/S0140-6736(13)60493-6  0.698
2013 Mason FE, Eisner DA, Morton MJ, Pollard CE, Trafford AW. Investigating the Effects of a Cardiotoxic Drug on Calcium Homeostasis in the Heart Biophysical Journal. 104: 604a. DOI: 10.1016/J.Bpj.2012.11.3350  0.802
2013 Greensmith DJ, Galli GL, Morton MJ, Pollard CE, Trafford AW, Eisner DA. Simultaneous Measurement of Cytoplasmic and SR Calcium during Modulation of Ryanodine Receptor Open Probability in Dog Ventricular Myocytes Biophysical Journal. 104: 438a. DOI: 10.1016/J.Bpj.2012.11.2433  0.883
2012 Li Y, Eisner DA, O'Neill SC. Do calcium waves propagate between cells and synchronize alternating calcium release in rat ventricular myocytes? The Journal of Physiology. 590: 6353-61. PMID 23090944 DOI: 10.1113/Jphysiol.2012.245241  0.583
2012 Li Q, O'Neill SC, Tao T, Li Y, Eisner D, Zhang H. Mechanisms by which cytoplasmic calcium wave propagation and alternans are generated in cardiac atrial myocytes lacking T-tubules-insights from a simulation study. Biophysical Journal. 102: 1471-82. PMID 22500747 DOI: 10.1016/J.Bpj.2012.03.007  0.687
2011 Richards MA, Clarke JD, Saravanan P, Voigt N, Dobrev D, Eisner DA, Trafford AW, Dibb KM. Transverse tubules are a common feature in large mammalian atrial myocytes including human. American Journal of Physiology. Heart and Circulatory Physiology. 301: H1996-2005. PMID 21841013 DOI: 10.1152/Ajpheart.00284.2011  0.688
2011 Bode EF, Briston SJ, Overend CL, O'Neill SC, Trafford AW, Eisner DA. Changes of SERCA activity have only modest effects on sarcoplasmic reticulum Ca2+ content in rat ventricular myocytes. The Journal of Physiology. 589: 4723-9. PMID 21825024 DOI: 10.1113/Jphysiol.2011.211052  0.796
2011 Briston SJ, Caldwell JL, Horn MA, Clarke JD, Richards MA, Greensmith DJ, Graham HK, Hall MC, Eisner DA, Dibb KM, Trafford AW. Impaired β-adrenergic responsiveness accentuates dysfunctional excitation-contraction coupling in an ovine model of tachypacing-induced heart failure. The Journal of Physiology. 589: 1367-82. PMID 21242250 DOI: 10.1113/Jphysiol.2010.203984  0.872
2011 Stokke MK, Briston SJ, Jølle GF, Manzoor I, Louch WE, Øyehaug L, Christensen G, Eisner DA, Trafford AW, Sejersted OM, Sjaastad I. Ca(2+) wave probability is determined by the balance between SERCA2-dependent Ca(2+) reuptake and threshold SR Ca(2+) content. Cardiovascular Research. 90: 503-12. PMID 21242164 DOI: 10.1093/Cvr/Cvr013  0.773
2011 Johnson D, Heijman J, Bode E, Greensmith D, Abi-Gerges N, Eisner D, Trafford A, Volders P. Increased ICaL Underlies Ventricular Action-Potential Prolongation After Spontaneous Ca2+ Release From The Sarcoplasmic Reticulum Heart Rhythm. 8: 1823. DOI: 10.1016/J.Hrthm.2011.09.038  0.864
2011 Bode EF, Briston SJ, Trafford AW, Eisner DA. Changes of SERCA Activity have Proportionately Smaller Effects on Sarcoplasmic Reticulum Calcium Content Biophysical Journal. 100. DOI: 10.1016/J.Bpj.2010.12.1787  0.573
2010 Dibb K, Eisner D. A small leak may sink a great ship but what does it do to the heart? Journal of Physiology. 588: 4849-4849. PMID 21173084 DOI: 10.1113/Jphysiol.2010.200840  0.692
2010 Greensmith DJ, Eisner DA, Nirmalan M. The effects of hydrogen peroxide on intracellular calcium handling and contractility in the rat ventricular myocyte. Cell Calcium. 48: 341-51. PMID 21106236 DOI: 10.1016/J.Ceca.2010.10.007  0.863
2010 Kashimura T, Briston SJ, Trafford AW, Napolitano C, Priori SG, Eisner DA, Venetucci LA. In the RyR2(R4496C) mouse model of CPVT, β-adrenergic stimulation induces Ca waves by increasing SR Ca content and not by decreasing the threshold for Ca waves. Circulation Research. 107: 1483-9. PMID 20966392 DOI: 10.1161/Circresaha.110.227744  0.771
2010 Eisner DA, George CH, Smith GL, Trafford AW, Venetucci LA. How does CaMKIIdelta phosphorylation of the cardiac ryanodine receptor contribute to inotropy? Proceedings of the National Academy of Sciences of the United States of America. 107: E123; author reply E. PMID 20660305 DOI: 10.1073/Pnas.1008809107  0.567
2010 Stokke MK, Hougen K, Sjaastad I, Louch WE, Briston SJ, Enger UH, Andersson KB, Christensen G, Eisner DA, Sejersted OM, Trafford AW. Reduced SERCA2 abundance decreases the propensity for Ca2+ wave development in ventricular myocytes. Cardiovascular Research. 86: 63-71. PMID 20019150 DOI: 10.1093/Cvr/Cvp401  0.757
2010 Dibb KM, Trafford AW, Eisner DA. Calcium signaling in cardiac muscle Handbook of Cell Signaling, 2/E. 2: 1027-1030. DOI: 10.1016/B978-0-12-374145-5.00128-5  0.504
2009 Dibb KM, Clarke JD, Horn MA, Richards MA, Graham HK, Eisner DA, Trafford AW. Characterization of an extensive transverse tubular network in sheep atrial myocytes and its depletion in heart failure. Circulation. Heart Failure. 2: 482-9. PMID 19808379 DOI: 10.1161/Circheartfailure.109.852228  0.781
2009 Borisova L, Wray S, Eisner DA, Burdyga T. How structure, Ca signals, and cellular communications underlie function in precapillary arterioles. Circulation Research. 105: 803-10. PMID 19713534 DOI: 10.1161/Circresaha.109.202960  0.72
2009 Eisner DA, Kashimura T, Venetucci LA, Trafford AW. From the ryanodine receptor to cardiac arrhythmias. Circulation Journal : Official Journal of the Japanese Circulation Society. 73: 1561-7. PMID 19667488 DOI: 10.1253/Circj.Cj-09-0478  0.804
2009 Eisner DA, Trafford AW. What is the purpose of the large sarcolemmal calcium flux on each heartbeat? American Journal of Physiology. Heart and Circulatory Physiology. 297: H493-4. PMID 19525376 DOI: 10.1152/Ajpheart.00423.2009  0.593
2009 Eisner DA, Dibb KM, Trafford AW. The mechanism and significance of the slow changes of ventricular action potential duration following a change of heart rate. Experimental Physiology. 94: 520-8. PMID 19270038 DOI: 10.1113/Expphysiol.2008.044008  0.56
2009 Murphy E, Eisner DA. Regulation of intracellular and mitochondrial sodium in health and disease. Circulation Research. 104: 292-303. PMID 19213964 DOI: 10.1161/Circresaha.108.189050  0.406
2009 Li Y, Díaz ME, Eisner DA, O'Neill S. The effects of membrane potential, SR Ca2+ content and RyR responsiveness on systolic Ca2+ alternans in rat ventricular myocytes. The Journal of Physiology. 587: 1283-92. PMID 19153161 DOI: 10.1113/Jphysiol.2008.164368  0.682
2009 Eisner DA, Cerbai E. Beating to time: calcium clocks, voltage clocks, and cardiac pacemaker activity. American Journal of Physiology. Heart and Circulatory Physiology. 296: H561-2. PMID 19151259 DOI: 10.1152/Ajpheart.00056.2009  0.338
2009 Eisner DA, Kashimura T, O'Neill SC, Venetucci LA, Trafford AW. What role does modulation of the ryanodine receptor play in cardiac inotropy and arrhythmogenesis? Journal of Molecular and Cellular Cardiology. 46: 474-81. PMID 19150449 DOI: 10.1016/J.Yjmcc.2008.12.005  0.803
2009 Stokke MK, Hougen K, Sjaastad I, Louch WE, Andersson KB, Christensen G, Eisner DA, Sejersted OM, Trafford AW. Ca2+ Wave Development in Ventricular Cardiomyocytes from Mice with Inducible Knockout of SERCA2 Biophysical Journal. 96: 275a. DOI: 10.1016/J.Bpj.2008.12.1361  0.778
2008 Venetucci LA, Eisner DA. Calsequestrin mutations and sudden death: a case of too little sarcoplasmic reticulum calcium buffering? Circulation Research. 103: 223-5. PMID 18669926 DOI: 10.1161/Circresaha.108.181636  0.635
2008 Tao T, O'Neill SC, Diaz ME, Li YT, Eisner DA, Zhang H. Alternans of cardiac calcium cycling in a cluster of ryanodine receptors: a simulation study. American Journal of Physiology. Heart and Circulatory Physiology. 295: H598-609. PMID 18515647 DOI: 10.1152/Ajpheart.01086.2007  0.669
2008 Venetucci LA, Trafford AW, O'Neill SC, Eisner DA. The sarcoplasmic reticulum and arrhythmogenic calcium release. Cardiovascular Research. 77: 285-92. PMID 18006483 DOI: 10.1093/Cvr/Cvm009  0.772
2008 Lim G, Venetucci L, Eisner DA, Casadei B. Does nitric oxide modulate cardiac ryanodine receptor function? Implications for excitation-contraction coupling. Cardiovascular Research. 77: 256-64. PMID 18006480 DOI: 10.1093/Cvr/Cvm012  0.53
2008 Garcia-Dorado D, Piper HM, Eisner DA. Sarcoplasmic reticulum and mitochondria in cardiac pathophysiology. Cardiovascular Research. 77: 231-3. PMID 18006429 DOI: 10.1093/Cvr/Cvm070  0.594
2007 Dibb KM, Eisner DA, Trafford AW. Regulation of systolic [Ca2+]i and cellular Ca2+ flux balance in rat ventricular myocytes by SR Ca2+, L-type Ca2+ current and diastolic [Ca2+]i. The Journal of Physiology. 585: 579-92. PMID 17932152 DOI: 10.1113/Jphysiol.2007.141473  0.782
2007 Case RM, Eisner D, Gurney A, Jones O, Muallem S, Verkhratsky A. Evolution of calcium homeostasis: from birth of the first cell to an omnipresent signalling system. Cell Calcium. 42: 345-50. PMID 17574670 DOI: 10.1016/J.Ceca.2007.05.001  0.591
2007 Dibb KM, Graham HK, Venetucci LA, Eisner DA, Trafford AW. Analysis of cellular calcium fluxes in cardiac muscle to understand calcium homeostasis in the heart. Cell Calcium. 42: 503-12. PMID 17509680 DOI: 10.1016/J.Ceca.2007.04.002  0.802
2007 Venetucci LA, Trafford AW, O'Neill SC, Eisner DA. Na/Ca exchange: regulator of intracellular calcium and source of arrhythmias in the heart. Annals of the New York Academy of Sciences. 1099: 315-25. PMID 17446473 DOI: 10.1196/Annals.1387.033  0.807
2007 Venetucci L, O'Neill SC, Eisner DA. Does the adenosine A2A receptor stimulate the ryanodine receptor? Cardiovascular Research. 73: 247-8; author reply . PMID 17137567 DOI: 10.1016/J.Cardiores.2006.10.023  0.638
2007 Venetucci LA, Trafford AW, Eisner DA. Increasing ryanodine receptor open probability alone does not produce arrhythmogenic calcium waves: threshold sarcoplasmic reticulum calcium content is required. Circulation Research. 100: 105-11. PMID 17110597 DOI: 10.1161/01.Res.0000252828.17939.00  0.792
2006 Murphy E, Eisner DA. How does endothelin-1 cause a sustained increase in intracellular sodium and calcium which lead to hypertrophy? Journal of Molecular and Cellular Cardiology. 41: 782-4. PMID 17027026 DOI: 10.1016/J.Yjmcc.2006.08.003  0.351
2006 Eisner DA, Venetucci LA, Trafford AW. Life, sudden death, and intracellular calcium. Circulation Research. 99: 223-4. PMID 16888244 DOI: 10.1161/01.Res.0000236790.08267.74  0.768
2006 Eisner DA, Li Y, O'Neill SC. Alternans of intracellular calcium: mechanism and significance. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 3: 743-5. PMID 16731482 DOI: 10.1016/J.Hrthm.2005.12.020  0.336
2006 Venetucci LA, Trafford AW, Díaz ME, O'Neill SC, Eisner DA. Reducing ryanodine receptor open probability as a means to abolish spontaneous Ca2+ release and increase Ca2+ transient amplitude in adult ventricular myocytes. Circulation Research. 98: 1299-305. PMID 16614307 DOI: 10.1161/01.Res.0000222000.35500.65  0.801
2006 Sipido KR, Varro A, Eisner D. Sodium calcium exchange as a target for antiarrhythmic therapy Handbook of Experimental Pharmacology. 171: 159-199. PMID 16610344 DOI: 10.1007/3-540-29715-4_6  0.66
2006 Kupittayanant P, Trafford AW, Díaz ME, Eisner DA. A mechanism distinct from the L-type Ca current or Na-Ca exchange contributes to Ca entry in rat ventricular myocytes. Cell Calcium. 39: 417-23. PMID 16563501 DOI: 10.1016/J.Ceca.2006.01.011  0.788
2006 Dibb K, Clarke J, Diffley L, Eisner D, Trafford A. Effect of PKA dependent phosphorylation on Ca homeostasis in the aged heart Journal of Molecular and Cellular Cardiology. 40: 992-993. DOI: 10.1016/J.Yjmcc.2006.03.214  0.722
2006 Clarke JD, Diffley LC, Dibb KM, Eisner DA, Trafford AW. CAMKII modulates cardiac excitation contraction coupling at multiple sites in ovine cardiac myocytes Journal of Molecular and Cellular Cardiology. 40: 992. DOI: 10.1016/J.Yjmcc.2006.03.212  0.55
2006 Borisova L, Eisner D, Wray S, Burdyga T. Calcium signalling and vasomotion in pre-capillary arterioles differs from that in arteries Journal of Molecular and Cellular Cardiology. 40: 926. DOI: 10.1016/J.Yjmcc.2006.03.031  0.472
2006 Venetucci L, Trafford A, Eisner D. Is high Ryanodine receptor open probability arrhythmogenic? Journal of Molecular and Cellular Cardiology. 40: 923. DOI: 10.1016/J.Yjmcc.2006.03.022  0.513
2005 Sipido KR, Eisner D. Something old, something new: Changing views on the cellular mechanisms of heart failure Cardiovascular Research. 68: 167-174. PMID 16202399 DOI: 10.1016/J.Cardiores.2005.08.011  0.609
2005 Díaz ME, Graham HK, O'neill SC, Trafford AW, Eisner DA. The control of sarcoplasmic reticulum Ca content in cardiac muscle. Cell Calcium. 38: 391-6. PMID 16139353 DOI: 10.1016/J.Ceca.2005.06.017  0.802
2005 Eisner DA, Diaz ME, Li Y, O'Neill SC, Trafford AW. Stability and instability of regulation of intracellular calcium. Experimental Physiology. 90: 3-12. PMID 15572459 DOI: 10.1113/Expphysiol.2004.029231  0.792
2005 Miller L, Eisner DA, O'Neill SC. SERCA Inhibition Decreases the L Type Ca Current in Cardiac Muscle Journal of Molecular and Cellular Cardiology. DOI: 10.1016/J.Yjmcc.2005.05.007  0.536
2004 Dibb KM, Rueckschloss U, Eisner DA, Isenberg G, Trafford AW. Mechanisms underlying enhanced cardiac excitation contraction coupling observed in the senescent sheep myocardium. Journal of Molecular and Cellular Cardiology. 37: 1171-81. PMID 15572047 DOI: 10.1016/J.Yjmcc.2004.09.005  0.789
2004 Eisner DA, Sipido KR. Sodium calcium exchange in the heart: necessity or luxury? Circulation Research. 95: 549-51. PMID 15375019 DOI: 10.1161/01.Res.0000143419.87518.9E  0.7
2004 O'Neill SC, Miller L, Hinch R, Eisner DA. Interplay between SERCA and sarcolemmal Ca2+ efflux pathways controls spontaneous release of Ca2+ from the sarcoplasmic reticulum in rat ventricular myocytes. The Journal of Physiology. 559: 121-8. PMID 15194743 DOI: 10.1113/Jphysiol.2003.058917  0.621
2004 Eisner DA, Díaz ME, O'Neill SC, Trafford AW. Physiological and pathological modulation of ryanodine receptor function in cardiac muscle. Cell Calcium. 35: 583-9. PMID 15110148 DOI: 10.1016/J.Ceca.2004.01.012  0.803
2004 Wray S, Ravens U, Verkhratsky A, Eisner D. Two centuries of excitation-contraction coupling. Cell Calcium. 35: 485-9. PMID 15110138 DOI: 10.1016/J.Ceca.2004.01.004  0.427
2004 Díaz ME, O'Neill SC, Eisner DA. Sarcoplasmic reticulum calcium content fluctuation is the key to cardiac alternans. Circulation Research. 94: 650-6. PMID 14752033 DOI: 10.1161/01.Res.0000119923.64774.72  0.688
2003 Bers DM, Eisner DA, Valdivia HH. Sarcoplasmic reticulum Ca2+ and heart failure: roles of diastolic leak and Ca2+ transport. Circulation Research. 93: 487-90. PMID 14500331 DOI: 10.1161/01.Res.0000091871.54907.6B  0.693
2003 Venetucci L, Trafford AW, Eisner DA. Illuminating sarcoplasmic reticulum calcium. Circulation Research. 93: 4-5. PMID 12855669 DOI: 10.1161/01.Res.0000082768.74160.8D  0.802
2003 Burdyga T, Shmygol A, Eisner DA, Wray S. A new technique for simultaneous and in situ measurements of Ca2+ signals in arteriolar smooth muscle and endothelial cells. Cell Calcium. 34: 27-33. PMID 12767890 DOI: 10.1016/S0143-4160(03)00019-8  0.667
2003 O'Neill SC, Eisner DA. pH-dependent and -independent effects inhibit Ca(2+)-induced Ca2+ release during metabolic blockade in rat ventricular myocytes. The Journal of Physiology. 550: 413-8. PMID 12766236 DOI: 10.1113/Jphysiol.2003.042846  0.522
2003 Trafford AW, Eisner DA. No role for a voltage sensitive release mechanism in cardiac muscle. Journal of Molecular and Cellular Cardiology. 35: 145-51. PMID 12606255 DOI: 10.1016/S0022-2828(02)00288-2  0.783
2003 Eisner DA, Isenberg G, Sipido KR. Normal and pathological excitation-contraction coupling in the heart -- an overview. The Journal of Physiology. 546: 3-4. PMID 12509474 DOI: 10.1113/Jphysiol.2002.036756  0.588
2002 Eisner DA, Trafford AW. Heart failure and the ryanodine receptor: does Occam's razor rule? Circulation Research. 91: 979-81. PMID 12456481 DOI: 10.1161/01.Res.0000045654.34731.Ff  0.796
2002 Smith RD, Eisner DA, Wray S. PH-induced changes in calcium: functional consequences and mechanisms of action in guinea pig portal vein. American Journal of Physiology. Heart and Circulatory Physiology. 283: H2518-26. PMID 12427597 DOI: 10.1152/Ajpheart.01102.2001  0.529
2002 Díaz ME, Eisner DA, O'Neill SC. Depressed ryanodine receptor activity increases variability and duration of the systolic Ca2+ transient in rat ventricular myocytes. Circulation Research. 91: 585-93. PMID 12364386 DOI: 10.1161/01.Res.0000035527.53514.C2  0.663
2002 Trafford AW, Díaz ME, O'Neill SC, Eisner DA. Integrative analysis of calcium signalling in cardiac muscle. Frontiers in Bioscience : a Journal and Virtual Library. 7: d843-52. PMID 11897570 DOI: 10.2741/Trafford  0.803
2002 Venetucci L, Trafford A, Díaz M, Eisner D. S2-1 Tetracaine abolishes spontaneous but increases stimulated SR Ca release Journal of Molecular and Cellular Cardiology. 34: A8. DOI: 10.1016/S0022-2828(02)90263-4  0.732
2002 Eisner D. IL-2 Integrative analysis of systolic Ca handling Journal of Molecular and Cellular Cardiology. 34: A5. DOI: 10.1016/S0022-2828(02)90252-X  0.489
2001 Díaz ME, Trafford AW, Eisner DA. The role of intracellular Ca buffers in determining the shape of the systolic Ca transient in cardiac ventricular myocytes. Pflã¼Gers Archiv : European Journal of Physiology. 442: 96-100. PMID 11374074 DOI: 10.1007/S004240000509  0.793
2001 Díaz ME, Trafford AW, Eisner DA. The effects of exogenous calcium buffers on the systolic calcium transient in rat ventricular myocytes. Biophysical Journal. 80: 1915-25. PMID 11259304 DOI: 10.1016/S0006-3495(01)76161-9  0.6
2001 Shmigol AV, Eisner DA, Wray S. Simultaneous measurements of changes in sarcoplasmic reticulum and cytosolic. The Journal of Physiology. 531: 707-13. PMID 11251052 DOI: 10.1111/J.1469-7793.2001.0707H.X  0.774
2001 Même W, O'Neill SC, Eisner DA. Low sodium inotropy is accompanied by diastolic Ca2+ gain and systolic loss in isolated guinea-pig ventricular myocytes Journal of Physiology. 530: 487-495. PMID 11158278 DOI: 10.1111/J.1469-7793.2001.0487K.X  0.677
2001 Trafford AW, Díaz ME, Eisner DA. Coordinated control of cell Ca(2+) loading and triggered release from the sarcoplasmic reticulum underlies the rapid inotropic response to increased L-type Ca(2+) current. Circulation Research. 88: 195-201. PMID 11157672 DOI: 10.1161/01.Res.88.2.195  0.797
2001 Overend CL, Eisner DA, O'Neill SC. Altered cardiac sarcoplasmic reticulum function of intact myocytes of rat ventricle during metabolic inhibition. Circulation Research. 88: 181-7. PMID 11157670 DOI: 10.1161/01.Res.88.2.181  0.671
2000 Eisner DA, Trafford AW. No Role for the Ryanodine Receptor in Regulating Cardiac Contraction? News in Physiological Sciences : An International Journal of Physiology Produced Jointly by the International Union of Physiological Sciences and the American Physiological Society. 15: 275-279. PMID 11390926 DOI: 10.1152/Physiologyonline.2000.15.5.275  0.767
2000 Choi HS, Trafford AW, Orchard CH, Eisner DA. The effect of acidosis on systolic Ca2+ and sarcoplasmic reticulum calcium content in isolated rat ventricular myocytes. The Journal of Physiology. 529: 661-8. PMID 11118496 DOI: 10.1111/J.1469-7793.2000.00661.X  0.804
2000 Eisner DA, Choi HS, Díaz ME, O'Neill SC, Trafford AW. Integrative analysis of calcium cycling in cardiac muscle. Circulation Research. 87: 1087-94. PMID 11110764 DOI: 10.1161/01.Res.87.12.1087  0.777
2000 Trafford AW, Sibbring GC, Díaz ME, Eisner DA. The effects of low concentrations of caffeine on spontaneous Ca release in isolated rat ventricular myocytes. Cell Calcium. 28: 269-76. PMID 11032782 DOI: 10.1054/Ceca.2000.0156  0.788
2000 Choi HS, Trafford AW, Eisner DA. Measurement of calcium entry and exit in quiescent rat ventricular myocytes. Pflã¼Gers Archiv : European Journal of Physiology. 440: 600-8. PMID 10958344 DOI: 10.1007/S004240000295  0.792
2000 Eisner DA, Díaz ME, O'Neill SC, Trafford AW. The ryanodine receptor: cause or consequence of diabetic heart failure? Journal of Molecular and Cellular Cardiology. 32: 1377-9. PMID 10861137 DOI: 10.1006/jmcc.2000.1163  0.487
2000 Díaz ME, Trafford AW, O'Neill SC, Eisner DA. Can changes of ryanodine receptor expression affect cardiac contractility? Cardiovascular Research. 45: 1068-71. PMID 10728434 DOI: 10.1016/S0008-6363(99)00412-5  0.647
2000 Coker SJ, Batey AJ, Lightbown ID, Díaz ME, Eisner DA. Effects of mefloquine on cardiac contractility and electrical activity in vivo, in isolated cardiac preparations, and in single ventricular myocytes. British Journal of Pharmacology. 129: 323-30. PMID 10694239 DOI: 10.1038/Sj.Bjp.0703060  0.51
2000 Trafford AW, Díaz ME, Sibbring GC, Eisner DA. Modulation of CICR has no maintained effect on systolic Ca2+: simultaneous measurements of sarcoplasmic reticulum and sarcolemmal Ca2+ fluxes in rat ventricular myocytes. The Journal of Physiology. 522: 259-70. PMID 10639102 DOI: 10.1111/J.1469-7793.2000.T01-2-00259.X  0.803
1999 Shmigol AV, Eisner DA, Wray S. The role of the sarcoplasmic reticulum as a Ca2+ sink in rat uterine smooth muscle cells. The Journal of Physiology. 520: 153-63. PMID 10517808 DOI: 10.1111/J.1469-7793.1999.00153.X  0.775
1999 Choi HS, Eisner DA. The effects of inhibition of the sarcolemmal Ca-ATPase on systolic calcium fluxes and intracellular calcium concentration in rat ventricular myocytes. Pflã¼Gers Archiv : European Journal of Physiology. 437: 966-71. PMID 10370076 DOI: 10.1007/S004240050868  0.685
1999 Bennett DL, O'Neill SC, Eisner DA. Strophanthidin-induced gain of Ca2+ occurs during diastole and not systole in guinea-pig ventricular myocytes. Pflã¼Gers Archiv : European Journal of Physiology. 437: 731-6. PMID 10087151 DOI: 10.1007/S004240050839  0.673
1999 Choi HS, Eisner DA. The role of sarcolemmal Ca2+-ATPase in the regulation of resting calcium concentration in rat ventricular myocytes. The Journal of Physiology. 515: 109-18. PMID 9925882 DOI: 10.1111/J.1469-7793.1999.109Ad.X  0.689
1999 Trafford AW, Díaz ME, Eisner DA. A novel, rapid and reversible method to measure Ca buffering and time-course of total sarcoplasmic reticulum Ca content in cardiac ventricular myocytes. Pflã¼Gers Archiv : European Journal of Physiology. 437: 501-3. PMID 9914410 DOI: 10.1007/S004240050808  0.79
1998 Trafford AW, Díaz ME, Eisner DA. Measurement of sarcoplasmic reticulum Ca content and sarcolemmal fluxes during the transient stimulation of the systolic Ca transient produced by caffeine. Annals of the New York Academy of Sciences. 853: 368-71. PMID 10603982 DOI: 10.1111/J.1749-6632.1998.Tb08302.X  0.781
1998 Shmigol A, Eisner DA, Wray S. Carboxyeosin decreases the rate of decay of the [Ca2+]i transient in uterine smooth muscle cells isolated from pregnant rats. Pflã¼Gers Archiv : European Journal of Physiology. 437: 158-60. PMID 9817801 DOI: 10.1007/S004240050761  0.774
1998 Trafford AW, Eisner DA. Another trigger for the heartbeat. The Journal of Physiology. 513: 1. PMID 9782153 DOI: 10.1111/J.1469-7793.1998.001By.X  0.792
1998 Eisner DA, Trafford AW, Díaz ME, Overend CL, O'Neill SC. The control of Ca release from the cardiac sarcoplasmic reticulum: regulation versus autoregulation. Cardiovascular Research. 38: 589-604. PMID 9747428 DOI: 10.1016/S0008-6363(98)00062-5  0.784
1998 Adams W, Trafford AW, Eisner DA. 2,3-Butanedione monoxime (BDM) decreases sarcoplasmic reticulum Ca content by stimulating Ca release in isolated rat ventricular myocytes. Pflã¼Gers Archiv : European Journal of Physiology. 436: 776-81. PMID 9716712 DOI: 10.1007/S004240050701  0.798
1998 Shmigol AV, Eisner DA, Wray S. Properties of voltage-activated [Ca2+]i transients in single smooth muscle cells isolated from pregnant rat uterus. The Journal of Physiology. 511: 803-11. PMID 9714861 DOI: 10.1111/J.1469-7793.1998.803Bg.X  0.776
1998 Trafford AW, Díaz ME, Eisner DA. Stimulation of Ca-induced Ca release only transiently increases the systolic Ca transient: measurements of Ca fluxes and sarcoplasmic reticulum Ca. Cardiovascular Research. 37: 710-7. PMID 9659455 DOI: 10.1016/S0008-6363(97)00266-6  0.783
1998 Overend CL, O'Neill SC, Eisner DA. The effect of tetracaine on stimulated contractions, sarcoplasmic reticulum Ca2+ content and membrane current in isolated rat ventricular myocytes. The Journal of Physiology. 507: 759-69. PMID 9508837 DOI: 10.1111/J.1469-7793.1998.759Bs.X  0.696
1998 Trafford AW, Díaz ME, Eisner DA. Ca-activated chloride current and Na-Ca exchange have different timecourses during sarcoplasmic reticulum Ca release in ferret ventricular myocytes. Pflã¼Gers Archiv : European Journal of Physiology. 435: 743-5. PMID 9479029 DOI: 10.1007/S004240050577  0.79
1998 Smith RD, Eisner DA, Wray S. The effects of changing intracellular pH on calcium and potassium currents in smooth muscle cells from the guinea-pig ureter. Pflã¼Gers Archiv : European Journal of Physiology. 435: 518-22. PMID 9446699 DOI: 10.1007/S004240050547  0.546
1997 Naderali EK, Buttell N, Taggart MJ, Bullock AJ, Eisner DA, Wray S. The role of the sarcolemmal Ca(2+)-ATPase in the pH transients associated with contraction in rat smooth muscle. The Journal of Physiology. 505: 329-36. PMID 9423176 DOI: 10.1111/J.1469-7793.1997.329Bb.X  0.756
1997 Trafford AW, Díaz ME, Negretti N, Eisner DA. Enhanced Ca2+ current and decreased Ca2+ efflux restore sarcoplasmic reticulum Ca2+ content after depletion. Circulation Research. 81: 477-84. PMID 9314828 DOI: 10.1161/01.Res.81.4.477  0.794
1997 Díaz ME, Trafford AW, O'Neill SC, Eisner DA. A measurable reduction of s.r. Ca content follows spontaneous Ca release in rat ventricular myocytes. Pflã¼Gers Archiv : European Journal of Physiology. 434: 852-4. PMID 9306022 DOI: 10.1007/S004240050475  0.741
1997 Overend CL, Eisner DA, O'Neill SC. The effect of tetracaine on spontaneous Ca2+ release and sarcoplasmic reticulum calcium content in rat ventricular myocytes. The Journal of Physiology. 502: 471-9. PMID 9279801 DOI: 10.1111/J.1469-7793.1997.471Bj.X  0.693
1997 Díaz ME, Trafford AW, O'Neill SC, Eisner DA. Measurement of sarcoplasmic reticulum Ca2+ content and sarcolemmal Ca2+ fluxes in isolated rat ventricular myocytes during spontaneous Ca2+ release. The Journal of Physiology. 501: 3-16. PMID 9174989 DOI: 10.1111/J.1469-7793.1997.003Bo.X  0.799
1996 Eisner DA, Trafford AW. A sideways look at sparks, quarks, puffs and blips. The Journal of Physiology. 497: 2. PMID 8951706 DOI: 10.1113/Jphysiol.1996.Sp021744  0.518
1996 Lamont C, Eisner DA. The sarcolemmal mechanisms involved in the control of diastolic intracellular calcium in isolated rat cardiac trabeculae. Pflã¼Gers Archiv : European Journal of Physiology. 432: 961-9. PMID 8781189 DOI: 10.1007/S004240050223  0.685
1996 Austin C, Dilly K, Eisner D, Wray S. Simultaneous measurement of intracellular pH, calcium, and tension in rat mesenteric vessels: effects of extracellular pH. Biochemical and Biophysical Research Communications. 222: 537-40. PMID 8670240 DOI: 10.1006/Bbrc.1996.0779  0.725
1996 Dilly KW, Doering AE, Adams WA, Austin C, Eisner DA. Intracellular pH is insensitive to changes in intracellular calcium concentration in isolated rat ventricular myocytes. Annals of the New York Academy of Sciences. 779: 529-31. PMID 8659870 DOI: 10.1111/J.1749-6632.1996.Tb44828.X  0.355
1996 Doering AE, Eisner DA, Lederer WJ. Cardiac Na-Ca exchange and pH. Annals of the New York Academy of Sciences. 779: 182-98. PMID 8659826 DOI: 10.1111/J.1749-6632.1996.Tb44786.X  0.558
1996 Díaz ME, Cook SJ, Chamunorwa JP, Trafford AW, Lancaster MK, O'Neill SC, Eisner DA. Variability of spontaneous Ca2+ release between different rat ventricular myocytes is correlated with Na(+)-Ca2+ exchange and [Na+]i. Circulation Research. 78: 857-62. PMID 8620606 DOI: 10.1161/01.Res.78.5.857  0.782
1995 Trafford AW, Lipp P, O'Neill SC, Niggli E, Eisner DA. Propagating calcium waves initiated by local caffeine application in rat ventricular myocytes. The Journal of Physiology. 489: 319-26. PMID 8847628 DOI: 10.1113/Jphysiol.1995.Sp021053  0.765
1995 Shmigol AV, Smith RD, Taggart MJ, Wray S, Eisner DA. Changes of pH affect calcium currents but not outward potassium currents in rat myometrial cells. Pflã¼Gers Archiv : European Journal of Physiology. 431: 135-7. PMID 8584412 DOI: 10.1007/Bf00374388  0.511
1995 Trafford AW, Díaz ME, O'Neill SC, Eisner DA. Comparison of subsarcolemmal and bulk calcium concentration during spontaneous calcium release in rat ventricular myocytes. The Journal of Physiology. 488: 577-86. PMID 8576849 DOI: 10.1113/Jphysiol.1995.Sp020991  0.794
1995 Baró I, Eisner DA. Factors controlling changes in intracellular Ca2+ concentration produced by noradrenaline in rat mesenteric artery smooth muscle cells. The Journal of Physiology. 482: 247-58. PMID 7714820 DOI: 10.1113/Jphysiol.1995.Sp020514  0.68
1995 Negretti N, Varro A, Eisner DA. Estimate of net calcium fluxes and sarcoplasmic reticulum calcium content during systole in rat ventricular myocytes. The Journal of Physiology. 486: 581-91. PMID 7473221 DOI: 10.1113/Jphysiol.1995.Sp020836  0.572
1994 Donoso P, O'Neill SC, Dilly KW, Negretti N, Eisner DA. Comparison of the effects of caffeine and other methylxanthines on [Ca2+]i in rat ventricular myocytes. British Journal of Pharmacology. 111: 455-8. PMID 8004389 DOI: 10.1111/J.1476-5381.1994.Tb14757.X  0.646
1994 Orchard CH, Eisner DA, Allen DG. Sydney Ringer viewed in a new light. Cardiovascular Research. 28: 1765-8. PMID 7867027 DOI: 10.1093/Cvr/28.12.1765  0.364
1994 Eisner DA, O'Neill SC, Donoso P. Properties of the fluorescent sodium indicator SBFI in rat and rabbit cardiac myocytes. Journal of Cardiovascular Electrophysiology. 5: 637-9. PMID 7527284 DOI: 10.1111/J.1540-8167.1994.Tb01305.X  0.449
1993 Varro A, Negretti N, Hester SB, Eisner DA. An estimate of the calcium content of the sarcoplasmic reticulum in rat ventricular myocytes. Pflã¼Gers Archiv : European Journal of Physiology. 423: 158-60. PMID 8488088 DOI: 10.1007/Bf00374975  0.678
1993 Negretti N, O'Neill SC, Eisner DA. The relative contributions of different intracellular and sarcolemmal systems to relaxation in rat ventricular myocytes. Cardiovascular Research. 27: 1826-30. PMID 8275530 DOI: 10.1093/Cvr/27.10.1826  0.67
1993 Trafford AW, O'Neill SC, Eisner DA. Factors affecting the propagation of locally activated systolic Ca transients in rat ventricular myocytes. Pflã¼Gers Archiv : European Journal of Physiology. 425: 181-3. PMID 8272377 DOI: 10.1007/Bf00374521  0.786
1993 Negretti N, O'Neill SC, Eisner DA. The effects of inhibitors of sarcoplasmic reticulum function on the systolic Ca2+ transient in rat ventricular myocytes. The Journal of Physiology. 468: 35-52. PMID 8254514 DOI: 10.1113/Jphysiol.1993.Sp019758  0.685
1993 Heaton RC, Wray S, Eisner DA. Effects of metabolic inhibition and changes of intracellular pH on potassium permeability and contraction of rat uterus. The Journal of Physiology. 465: 43-56. PMID 8229844 DOI: 10.1113/Jphysiol.1993.Sp019665  0.592
1993 Baró I, O'Neill SC, Eisner DA. Changes of intracellular [Ca2+] during refilling of sarcoplasmic reticulum in rat ventricular and vascular smooth muscle. The Journal of Physiology. 465: 21-41. PMID 8229834 DOI: 10.1113/Jphysiol.1993.Sp019664  0.667
1993 Eisner DA, Smith GL, O'Neill SC. The effects of lactic acid production on contraction and intracellular pH during hypoxia in cardiac muscle. Basic Research in Cardiology. 88: 421-9. PMID 8117248 DOI: 10.1007/Bf00795409  0.312
1992 Donoso P, Mill JG, O'Neill SC, Eisner DA. Fluorescence measurements of cytoplasmic and mitochondrial sodium concentration in rat ventricular myocytes. The Journal of Physiology. 448: 493-509. PMID 1593474 DOI: 10.1113/Jphysiol.1992.Sp019053  0.404
1992 Baró I, Eisner DA. The effects of thapsigargin on [Ca2+]i in isolated rat mesenteric artery vascular smooth muscle cells. Pflã¼Gers Archiv : European Journal of Physiology. 420: 115-7. PMID 1553258 DOI: 10.1007/Bf00378652  0.646
1992 Elliott AC, Smith GL, Eisner DA, Allen DG. Metabolic changes during ischaemia and their role in contractile failure in isolated ferret hearts. The Journal of Physiology. 454: 467-90. PMID 1474498 DOI: 10.1113/Jphysiol.1992.Sp019274  0.328
1992 Toescu EC, O'Neill SC, Petersen OH, Eisner DA. Caffeine inhibits the agonist-evoked cytosolic Ca2+ signal in mouse pancreatic acinar cells by blocking inositol trisphosphate production. The Journal of Biological Chemistry. 267: 23467-70. PMID 1429689  0.569
1992 Toescu EC, O'Neill SC, Petersen OH, Eisner DA. Inhibiton by caffeine of ACh-evoked cytoplasmic Ca2+ signals studied by simultaneous measurements of [Ca2+](i) and [caffeine](i) in single mouse pancreatic acinar cells Journal of Physiology. 446: 201P.  0.556
1991 O'Neill SC, Valdeolmillos M, Lamont C, Donoso P, Eisner DA. The contribution of Na-Ca exchange to relaxation in mammalian cardiac muscle. Annals of the New York Academy of Sciences. 639: 444-52. PMID 1785867 DOI: 10.1111/J.1749-6632.1991.Tb17331.X  0.56
1991 Eiesland J, Baro I, Raimbach S, Eisner DA, Wray S. Intracellular pH and buffering power measured in isolated single cells from pregnant rat uterus. Experimental Physiology. 76: 815-8. PMID 1742019 DOI: 10.1113/Expphysiol.1991.Sp003548  0.479
1991 Eisner D. Intracellular Calcium Regulation. Edited by Felix Bronner. Pp. 480. Wiley‐Liss, New York, 1990. $79.50 hardback. ISBN 0‐471‐56216‐5 Experimental Physiology. 76: 306-307. DOI: 10.1113/Expphysiol.1998.Sp004192  0.313
1990 Duchen MR, Valdeolmillos M, O'Neill SC, Eisner DA. Effects of metabolic blockade on the regulation of intracellular calcium in dissociated mouse sensory neurones. The Journal of Physiology. 424: 411-26. PMID 2391656 DOI: 10.1113/Jphysiol.1990.Sp018074  0.671
1990 O'Neill SC, Mill JG, Eisner DA. Local activation of contraction in isolated rat ventricular myocytes. The American Journal of Physiology. 258: C1165-8. PMID 2360623 DOI: 10.1152/Ajpcell.1990.258.6.C1165  0.643
1990 O'Neill SC, Donoso P, Eisner DA. The role of [Ca2+]i and [Ca2+] sensitization in the caffeine contracture of rat myocytes: measurement of [Ca2+]i and [caffeine]i. The Journal of Physiology. 425: 55-70. PMID 2213589 DOI: 10.1113/Jphysiol.1990.Sp018092  0.646
1990 O'Neill SC, Eisner DA. A mechanism for the effects of caffeine on Ca2+ release during diastole and systole in isolated rat ventricular myocytes. The Journal of Physiology. 430: 519-36. PMID 2086772 DOI: 10.1113/Jphysiol.1990.Sp018305  0.687
1990 Eisner DA. Na-Ca exchange in cardiac muscle Journal of Molecular and Cellular Cardiology. 22. DOI: 10.1016/0022-2828(90)91936-2  0.564
1989 O'Neill SC, Valdeolmillos M, Smith GL, Eisner DA. The effects of metabolic inhibition on intracellular pH and Ca. Molecular and Cellular Biochemistry. 89: 199-203. PMID 2811865 DOI: 10.1007/Bf00220776  0.634
1989 Valdeolmillos M, O'Neill SC, Smith GL, Eisner DA. Calcium-induced calcium release activates contraction in intact cardiac cells. Pflã¼Gers Archiv : European Journal of Physiology. 413: 676-8. PMID 2726431 DOI: 10.1007/Bf00581820  0.554
1989 Eisner DA, Nichols CG, O'Neill SC, Smith GL, Valdeolmillos M. The effects of metabolic inhibition on intracellular calcium and pH in isolated rat ventricular cells. The Journal of Physiology. 411: 393-418. PMID 2614727 DOI: 10.1113/Jphysiol.1989.Sp017580  0.657
1989 Biscoe TJ, Duchen MR, Eisner DA, O'Neill SC, Valdeolmillos M. Measurements of intracellular Ca2+ in dissociated type I cells of the rabbit carotid body. The Journal of Physiology. 416: 421-34. PMID 2607457 DOI: 10.1113/Jphysiol.1989.Sp017769  0.671
1988 O'Neill SC, Valdeolmillos M, Eisner DA. The effects of nickel on contraction and membrane current in isolated rat myocytes. Quarterly Journal of Experimental Physiology (Cambridge, England). 73: 1017-20. PMID 3237980 DOI: 10.1113/Expphysiol.1988.Sp003213  0.58
1988 Smith GL, Valdeolmillos M, Eisner DA, Allen DG. Effects of rapid application of caffeine on intracellular calcium concentration in ferret papillary muscles. The Journal of General Physiology. 92: 351-68. PMID 3225553 DOI: 10.1085/Jgp.92.3.351  0.679
1987 Vaughan-Jones RD, Eisner DA, Lederer WJ. Effects of changes of intracellular pH on contraction in sheep cardiac Purkinje fibers. The Journal of General Physiology. 89: 1015-32. PMID 3612086 DOI: 10.1085/Jgp.89.6.1015  0.322
1987 Eisner DA, Valdeolmillos M, Wray S. The effects of membrane potential on active and passive sodium transport in Xenopus oocytes. The Journal of Physiology. 385: 643-59. PMID 2443675  0.441
1986 Allen DG, Eisner DA, Morris PG, Pirolo JS, Smith GL. Metabolic consequences of increasing intracellular calcium and force production in perfused ferret hearts. The Journal of Physiology. 376: 121-41. PMID 3795073 DOI: 10.1113/Jphysiol.1986.Sp016145  0.423
1986 Eisner DA, Valdeolmillos M. A study of intracellular calcium oscillations in sheep cardiac Purkinje fibres measured at the single cell level. The Journal of Physiology. 372: 539-56. PMID 3723418 DOI: 10.1113/Jphysiol.1986.Sp016024  0.604
1986 Cannell MB, Eisner DA, Lederer WJ, Valdeolmillos M. Effects of membrane potential on intracellular calcium concentration in sheep Purkinje fibres in sodium-free solutions. The Journal of Physiology. 381: 193-203. PMID 3625534 DOI: 10.1113/Jphysiol.1986.Sp016322  0.613
1986 Eisner DA, Valdeolmillos M. Measurement of intracellular calcium during the development and relaxation of tonic tension in sheep Purkinje fibres. The Journal of Physiology. 375: 269-81. PMID 2432223 DOI: 10.1113/Jphysiol.1986.Sp016116  0.555
1986 Eisner DA. The role of intracellular Ca ions in the therapeutic and toxic effects of cardiac glycosides and catecholamines. Journal of Cardiovascular Pharmacology. 8: S2-9. PMID 2429107  0.611
1985 Nieman CJ, Eisner DA. Effects of caffeine, tetracaine, and ryanodine on calcium-dependent oscillations in sheep cardiac Purkinje fibers. The Journal of General Physiology. 86: 877-89. PMID 4078558 DOI: 10.1085/Jgp.86.6.877  0.541
1985 Allen DG, Eisner DA, Wray SC. Birthday present for digitalis. Nature. 316: 674-5. PMID 4033766 DOI: 10.1038/316674A0  0.436
1985 Eisner DA, Valdeolmillos M. The mechanism of the increase of tonic tension produced by caffeine in sheep cardiac Purkinje fibres. The Journal of Physiology. 364: 313-26. PMID 4032302 DOI: 10.1113/Jphysiol.1985.Sp015747  0.664
1985 Allen DG, Eisner DA, Pirolo JS, Smith GL. The relationship between intracellular calcium and contraction in calcium-overloaded ferret papillary muscles. The Journal of Physiology. 364: 169-82. PMID 4032294 DOI: 10.1113/Jphysiol.1985.Sp015737  0.642
1985 Valdeolmillos M, Eisner DA. The effects of ryanodine on calcium-overloaded sheep cardiac Purkinje fibers. Circulation Research. 56: 452-6. PMID 3971516 DOI: 10.1161/01.Res.56.3.452  0.376
1985 Wray S, Eisner DA, Allen DG. Two hundred years of the foxglove. Medical History. Supplement. 132-50. PMID 3915521 DOI: 10.1017/S0025727300070551  0.414
1985 Eisner DA, Lederer WJ. Na-Ca exchange: stoichiometry and electrogenicity. The American Journal of Physiology. 248: C189-202. PMID 2579566 DOI: 10.1152/Ajpcell.1985.248.3.C189  0.602
1985 Vaughan-Jones RD, Eisner DA, Lederer WJ. The effects of intracellular Na on contraction and intracellular pH in mammalian cardiac muscle. Advances in Myocardiology. 5: 313-30. PMID 2578682 DOI: 10.1007/978-1-4757-1287-2_24  0.616
1985 Requena J, Whittembury J, Tiffert T, Eisner DA, Mullins LJ. The influence of chemical agents on the level of ionized [Ca2+] in squid axons. The Journal of General Physiology. 85: 789-804. PMID 2410536 DOI: 10.1085/Jgp.85.6.789  0.619
1985 Eisner DA, Wray SC. Ion pumping in biological membranes Contemporary Physics. 26: 3-21. DOI: 10.1080/00107518508210736  0.441
1984 Allen DG, Eisner DA, Orchard CH. Characterization of oscillations of intracellular calcium concentration in ferret ventricular muscle. The Journal of Physiology. 352: 113-28. PMID 6747885 DOI: 10.1113/Jphysiol.1984.Sp015281  0.596
1984 Allen DG, Eisner DA, Orchard CH. Factors influencing free intracellular calcium concentration in quiescent ferret ventricular muscle. The Journal of Physiology. 350: 615-30. PMID 6747860 DOI: 10.1113/Jphysiol.1984.Sp015221  0.666
1984 Eisner DA, Orchard CH, Allen DG. Control of intracellular ionized calcium concentration by sarcolemmal and intracellular mechanisms. Journal of Molecular and Cellular Cardiology. 16: 137-46. PMID 6716490 DOI: 10.1016/S0022-2828(84)80702-6  0.672
1984 Lederer WJ, Sheu SS, Vaughan-Jones RD, Eisner DA. The effects of Na-Ca exchange on membrane currents in sheep cardiac Purkinje fibers. Society of General Physiologists Series. 38: 373-80. PMID 6695211  0.407
1984 Requena J, Whittembury J, Tiffert T, Eisner DA, Mullins LJ. A comparison of measurements of intracellular Ca by Ca electrode and optical indicators. Biochimica Et Biophysica Acta. 805: 393-404. PMID 6509093 DOI: 10.1016/0167-4889(84)90023-5  0.604
1984 Eisner DA, Lederer WJ, Vaughan-Jones RD. The quantitative relationship between twitch tension and intracellular sodium activity in sheep cardiac Purkinje fibres. The Journal of Physiology. 355: 251-66. PMID 6092625 DOI: 10.1113/Jphysiol.1984.Sp015417  0.389
1983 Orchard CH, Eisner DA, Allen DG. Oscillations of intracellular Ca2+ in mammalian cardiac muscle. Nature. 304: 735-8. PMID 6888540 DOI: 10.1038/304735A0  0.686
1983 Eisner DA, Lederer WJ, Vaughan-Jones RD. The control of tonic tension by membrane potential and intracellular sodium activity in the sheep cardiac Purkinje fibre. The Journal of Physiology. 335: 723-43. PMID 6875898 DOI: 10.1113/Jphysiol.1983.Sp014560  0.423
1983 Vaughan-Jones RD, Lederer WJ, Eisner DA. Ca2+ ions can affect intracellular pH in mammalian cardiac muscle. Nature. 301: 522-4. PMID 6823331 DOI: 10.1038/301522A0  0.612
1983 Allen DG, Eisner DA, Lab MJ, Orchard CH. The effects of low sodium solutions on intracellular calcium concentration and tension in ferret ventricular muscle. The Journal of Physiology. 345: 391-407. PMID 6663506 DOI: 10.1113/Jphysiol.1983.Sp014984  0.572
1983 Eisner DA, Vaughan-Jones RD. Do calcium-activated potassium channels exist in the heart? Cell Calcium. 4: 371-86. PMID 6323002 DOI: 10.1016/0143-4160(83)90015-5  0.568
1983 Eisner DA, Lederer WJ, Sheu SS. The role of intracellular sodium activity in the anti-arrhythmic action of local anaesthetics in sheep Purkinje fibres. The Journal of Physiology. 340: 239-57. PMID 6310096 DOI: 10.1113/Jphysiol.1983.Sp014761  0.354
1983 Eisner DA, Lederer WJ, Vaughan-Jones RD. Effects of Sodium Pump Inhibition on Contraction in Sheep Cardiac Purkinje Fibers Current Topics in Membranes and Transport. 19: 885-890. DOI: 10.1016/S0070-2161(08)60645-0  0.5
1982 Arnold L, Page J, Attwell D, Cannell M, Eisner DA. The dependence on heart rate of the human ventricular action potential duration. Cardiovascular Research. 16: 547-51. PMID 7151099 DOI: 10.1093/Cvr/16.10.547  0.308
1982 Lederer WJ, Eisner DA. The effects of sodium pump activity on the slow inward current in sheep cardiac Purkinje fibres. Proceedings of the Royal Society of London. Series B, Biological Sciences. 214: 249-62. PMID 6127682 DOI: 10.1098/Rspb.1982.0008  0.321
1981 Eisner DA, Lederer WJ, Vaughan-Jones RD. The effects of rubidium ions and membrane potentials on the intracellular sodium activity of sheep Purkinje fibres. The Journal of Physiology. 317: 189-205. PMID 7310732 DOI: 10.1113/Jphysiol.1981.Sp013820  0.33
1981 Eisner DA, Lederer WJ, Vaughan-Jones RD. The dependence of sodium pumping and tension on intracellular sodium activity in voltage-clamped sheep Purkinje fibres. The Journal of Physiology. 317: 163-87. PMID 7310731 DOI: 10.1113/Jphysiol.1981.Sp013819  0.3
1981 Attwell D, Cohen I, Eisner DA. The effects of heart rate on the action potential of guinea-pig and human ventricular muscle. The Journal of Physiology. 313: 439-61. PMID 7277229 DOI: 10.1113/Jphysiol.1981.Sp013675  0.344
1979 Eisner DA, Lederer WJ. Inotropic and arrhythmogenic effects of potassium-depleted solutions on mammalian cardiac muscle. The Journal of Physiology. 294: 255-77. PMID 512946 DOI: 10.1113/Jphysiol.1979.Sp012929  0.461
1979 Eisner DA, Lederer WJ, Noble D. Caffeine and tetracaine abolish the slow inward calcium current in sheep cardiac Purkinje fibres [proceedings]. The Journal of Physiology. 293: 76P-77P. PMID 501653  0.458
1977 Attwell D, Cohen I, Eisner DA, Noble D. Activity dependent changes in mammalian ventricular muscle [proceedings]. The Journal of Physiology. 271: 17P-18P. PMID 925971  0.379
1977 Cohen I, Eisner DA, Giles WR, Noble D. Effect of adrenaline on the potassium current reversal potential in cardiac Purkinje fibres of the sheep [proceedings]. The Journal of Physiology. 272: 53P-54P. PMID 592151  0.404
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