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Ming-Kai Chen, Ph.D. - Publications

Affiliations: 
2008 Johns Hopkins University, Baltimore, MD 
Area:
Radiology, Neuroscience Biology, Toxicology
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27 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Carson RE, Naganawa M, Toyonaga T, Koohsari S, Yang Y, Chen MK, Matuskey D, Finnema SJ. Imaging of Synaptic Density in Neurodegenerative Disorders. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 63: 60S-67S. PMID 35649655 DOI: 10.2967/jnumed.121.263201  0.308
2020 Finnema SJ, Toyonaga T, Detyniecki K, Chen MK, Dias M, Wang Q, Lin SF, Naganawa M, Gallezot JD, Lu Y, Nabulsi NB, Huang Y, Spencer DD, Carson RE. Reduced synaptic vesicle protein 2A binding in temporal lobe epilepsy: A [ C]UCB-J positron emission tomography study. Epilepsia. PMID 32944949 DOI: 10.1111/Epi.16653  0.352
2020 Smart K, Liu H, Matuskey D, Chen MK, Torres K, Nabulsi N, Labaree D, Ropchan J, Hillmer AT, Huang Y, Carson RE. Binding of the synaptic vesicle radiotracer [C]UCB-J is unchanged during functional brain activation using a visual stimulation task. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X20946198. PMID 32757741 DOI: 10.1177/0271678X20946198  0.371
2020 Mecca AP, Chen MK, O'Dell RS, Naganawa M, Toyonaga T, Godek TA, Harris JE, Bartlett HH, Zhao W, Nabulsi NB, Wyk BCV, Varma P, Arnsten AFT, Huang Y, Carson RE, et al. In vivo measurement of widespread synaptic loss in Alzheimer's disease with SV2A PET. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 32400950 DOI: 10.1002/Alz.12097  0.348
2020 Mecca AP, McDonald JW, Michalak HR, Godek TA, Harris JE, Pugh EA, Kemp EC, Chen MK, Salardini A, Nabulsi NB, Lim K, Huang Y, Carson RE, Strittmatter SM, van Dyck CH. PET imaging of mGluR5 in Alzheimer's disease. Alzheimer's Research & Therapy. 12: 15. PMID 31954399 DOI: 10.1186/S13195-020-0582-0  0.361
2020 O'Dell R, Mecca A, Chen M, Godek T, Harris J, Bartlett H, Zhao W, Naganawa M, Toyonaga T, Lu Y, Nabulsi N, Wyk BV, Varma P, Arnsten A, Huang Y, et al. ASSOCIATION BETWEEN CEREBRAL AMYLOID ACCUMULATION AND SYNAPTIC DENSITY IN ALZHEIMER'S DISEASE: A MULTITRACER PET STUDY The American Journal of Geriatric Psychiatry. 28: S123-S124. DOI: 10.1016/J.Jagp.2020.01.153  0.341
2019 Tuisku J, Plavén-Sigray P, Gaiser EC, Airas L, Al-Abdulrasul H, Brück A, Carson RE, Chen MK, Cosgrove KP, Ekblad L, Esterlis I, Farde L, Forsberg A, Halldin C, Helin S, et al. Effects of age, BMI and sex on the glial cell marker TSPO - a multicentre [C]PBR28 HRRT PET study. European Journal of Nuclear Medicine and Molecular Imaging. PMID 31363804 DOI: 10.1007/S00259-019-04403-7  0.309
2018 Ye Q, Wu J, Lu Y, Naganawa M, Gallezot JD, Ma T, Liu Y, Tanoue L, Detterbeck F, Blasberg J, Chen MK, Casey M, Carson RE, Liu C. Improved discrimination between benign and malignant LDCT screening-detected lung nodules with dynamic over static 18F-FDG PET as a function of injected dose. Physics in Medicine and Biology. PMID 30095083 DOI: 10.1088/1361-6560/Aad97F  0.323
2018 Mecca AP, McDonald JW, Michalak HR, Godek T, Harris J, Chen M, Nabulsi NB, Salardini A, Carson RE, Strittmatter SM, Dyck CHv. Ic-04-03: Pet Imaging Of Metabotropic Glutamate Receptor 5 Binding In Alzheimer'S Disease Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.2051  0.347
2018 Mecca AP, Chen M, Naganawa M, Finnema SJ, Toyonaga T, Lin S, McDonald JW, Michalak HR, Nabulsi NB, Huang Y, Arnsten AF, Carson RE, van Dyck CH. Initial Experience with PET Imaging of Synaptic Density (SV2A) in Alzheimer's Disease: A New Biomarker for Clinical Trials? The American Journal of Geriatric Psychiatry. 26: S145-S146. DOI: 10.1016/J.Jagp.2018.01.176  0.323
2017 Finnema SJ, Nabulsi NB, Mercier J, Lin SF, Chen MK, Matuskey D, Gallezot JD, Henry S, Hannestad J, Huang Y, Carson RE. Kinetic evaluation and test-retest reproducibility of [(11)C]UCB-J, a novel radioligand for positron emission tomography imaging of synaptic vesicle glycoprotein 2A in humans. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X17724947. PMID 28792356 DOI: 10.1177/0271678X17724947  0.335
2016 Finnema SJ, Nabulsi NB, Eid T, Detyniecki K, Lin SF, Chen MK, Dhaher R, Matuskey D, Baum E, Holden D, Spencer DD, Mercier J, Hannestad J, Huang Y, Carson RE. Imaging synaptic density in the living human brain. Science Translational Medicine. 8: 348ra96. PMID 27440727 DOI: 10.1126/Scitranslmed.Aaf6667  0.374
2016 Chen MK, Menard DH, Cheng DW. Determining the minimal required radioactivity of 18F-FDG for reliable semi-quantification in PET-CT imaging: a phantom study. Journal of Nuclear Medicine Technology. PMID 26769598 DOI: 10.2967/Jnmt.115.165258  0.325
2015 Park E, Gallezot JD, Delgadillo A, Liu S, Planeta B, Lin SF, O'Connor KC, Lim K, Lee JY, Chastre A, Chen MK, Seneca N, Leppert D, Huang Y, Carson RE, et al. (11)C-PBR28 imaging in multiple sclerosis patients and healthy controls: test-retest reproducibility and focal visualization of active white matter areas. European Journal of Nuclear Medicine and Molecular Imaging. 42: 1081-92. PMID 25833352 DOI: 10.1007/S00259-015-3043-4  0.316
2015 Lin SF, Labaree D, Chen MK, Holden D, Gallezot JD, Kapinos M, Teng JK, Najafzadeh S, Plisson C, Rabiner EA, Gunn RN, Carson RE, Huang Y. Further evaluation of [11C]MP-10 as a radiotracer for phosphodiesterase 10A: PET imaging study in rhesus monkeys and brain tissue metabolite analysis. Synapse (New York, N.Y.). 69: 86-95. PMID 25450608 DOI: 10.1002/Syn.21792  0.385
2008 Chen MK, Guilarte TR. Translocator protein 18 kDa (TSPO): molecular sensor of brain injury and repair. Pharmacology & Therapeutics. 118: 1-17. PMID 18374421 DOI: 10.1016/J.Pharmthera.2007.12.004  0.566
2008 Chen MK, Kuwabara H, Zhou Y, Adams RJ, Brasić JR, McGlothan JL, Verina T, Burton NC, Alexander M, Kumar A, Wong DF, Guilarte TR. VMAT2 and dopamine neuron loss in a primate model of Parkinson's disease. Journal of Neurochemistry. 105: 78-90. PMID 17988241 DOI: 10.1111/J.1471-4159.2007.05108.X  0.644
2007 Guilarte TR, Chen MK. Manganese inhibits NMDA receptor channel function: implications to psychiatric and cognitive effects. Neurotoxicology. 28: 1147-52. PMID 17662456 DOI: 10.1016/J.Neuro.2007.06.005  0.53
2006 Guilarte TR, McGlothan JL, Degaonkar M, Chen MK, Barker PB, Syversen T, Schneider JS. Evidence for cortical dysfunction and widespread manganese accumulation in the nonhuman primate brain following chronic manganese exposure: a 1H-MRS and MRI study. Toxicological Sciences : An Official Journal of the Society of Toxicology. 94: 351-8. PMID 16968886 DOI: 10.1093/Toxsci/Kfl106  0.493
2006 Guilarte TR, Chen MK, McGlothan JL, Verina T, Wong DF, Zhou Y, Alexander M, Rohde CA, Syversen T, Decamp E, Koser AJ, Fritz S, Gonczi H, Anderson DW, Schneider JS. Nigrostriatal dopamine system dysfunction and subtle motor deficits in manganese-exposed non-human primates. Experimental Neurology. 202: 381-90. PMID 16925997 DOI: 10.1016/J.Expneurol.2006.06.015  0.54
2006 Zhou Y, Chen MK, Endres CJ, Ye W, Brasić JR, Alexander M, Crabb AH, Guilarte TR, Wong DF. An extended simplified reference tissue model for the quantification of dynamic PET with amphetamine challenge. Neuroimage. 33: 550-63. PMID 16920365 DOI: 10.1016/J.Neuroimage.2006.06.038  0.529
2006 Chen MK, Guilarte TR. Imaging the peripheral benzodiazepine receptor response in central nervous system demyelination and remyelination. Toxicological Sciences : An Official Journal of the Society of Toxicology. 91: 532-9. PMID 16554315 DOI: 10.1093/Toxsci/Kfj172  0.586
2006 Chen MK, Lee JS, McGlothan JL, Furukawa E, Adams RJ, Alexander M, Wong DF, Guilarte TR. Acute manganese administration alters dopamine transporter levels in the non-human primate striatum. Neurotoxicology. 27: 229-36. PMID 16325911 DOI: 10.1016/J.Neuro.2005.10.008  0.558
2006 Chen M, Mecca AP, Naganawa M, Finnema SJ, Toyonaga T, Gallezot J, McDonald JW, Michalak HR, Nabulsi NB, Huang Y, Arnsten AF, Carson RE, van Dyck CH. P2-365: PET IMAGING OF SYNAPTIC DENSITY (SYNAPTIC VESICLE GLYCOPROTEIN 2A, SV2A) IN ALZHEIMER'S DISEASE: INITIAL EXPERIENCE Alzheimer's & Dementia. 14: P832-P832. DOI: 10.1016/J.Jalz.2018.06.1056  0.318
2005 Hardwick MJ, Chen MK, Baidoo K, Pomper MG, Guilarte TR. In vivo imaging of peripheral benzodiazepine receptors in mouse lungs: a biomarker of inflammation. Molecular Imaging. 4: 432-8. PMID 16285905 DOI: 10.2310/7290.2005.05133  0.497
2005 Zhou Y, Ye W, Chen M, Kumar A, Alexander M, Endres CJ, Guilarte TR, Wong DF. A generalized reference tissue model for quantification of dynamic PET with bolus plus continuous infusion tracer administration and pharmacological challenge Journal of Cerebral Blood Flow & Metabolism. 25: S645-S645. DOI: 10.1038/Sj.Jcbfm.9591524.0645  0.562
2004 Chen MK, Baidoo K, Verina T, Guilarte TR. Peripheral benzodiazepine receptor imaging in CNS demyelination: functional implications of anatomical and cellular localization. Brain : a Journal of Neurology. 127: 1379-92. PMID 15069023 DOI: 10.1093/Brain/Awh161  0.525
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