Alexander Varshavsky - Publications

Affiliations: 
Biology and Biological Engineering California Institute of Technology, Pasadena, CA 
Area:
Protein degradation, ubiquitin
Website:
http://www.bbe.caltech.edu/content/alexander-j-varshavsky

229 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Melnykov A, Chen SJ, Varshavsky A. Gid10 as an alternative N-recognin of the Pro/N-degron pathway. Proceedings of the National Academy of Sciences of the United States of America. PMID 31337681 DOI: 10.1073/pnas.1908304116  0.72
2018 Xie J, Hu Q, Huang Z, Zhou Z, Pei F. Comparison of three routes of administration of tranexamic acid in primary unilateral total knee arthroplasty: Analysis of a national database. Thrombosis Research. 173: 96-101. PMID 30500676 DOI: 10.1016/j.thromres.2018.11.025  0.52
2018 Pu Z, Zhao M, Zhang Y, Sun W, Bao Y. Dynamic Description of the Catalytic Cycle of Malate Enzyme:Stereoselective Recognition of Substrate, Chemical Reaction and Ligand Release. The Journal of Physical Chemistry. B. PMID 30500201 DOI: 10.1021/acs.jpcb.8b05135  0.4
2018 Choi I, Yang S, Choi TL. Preparing Semiconducting Nanoribbons with Tunable Length and Width via Crystallization-Driven Self-Assembly of a Simple Conjugated Homopolymer. Journal of the American Chemical Society. PMID 30500176 DOI: 10.1021/jacs.8b10406  0.32
2018 Xu J, Zhao X, Wang Z, Xu H, Hu J, Ma J, Liu Y. Biodegradable Natural Pectin-Based Flexible Multilevel Resistive Switching Memory for Transient Electronics. Small (Weinheim An Der Bergstrasse, Germany). e1803970. PMID 30500108 DOI: 10.1002/smll.201803970  0.4
2018 Zhang Y, Xia Y, Yan S, Han J, Chen Y, Zhai W, Gao Z. One-step green synthesis of composition-tunable Pt-Cu alloy nanowire networks with high catalytic activity for 4-nitrophenol reduction. Dalton Transactions (Cambridge, England : 2003). PMID 30499571 DOI: 10.1039/c8dt03810d  0.44
2018 Chen D, Pan X, Xie F, Lu Y, Zou H, Yin C, Zhang Y, Gao J. Codelivery of doxorubicin and elacridar to target both liver cancer cells and stem cells by polylactide-co-glycolide/d-alpha-tocopherol polyethylene glycol 1000 succinate nanoparticles. International Journal of Nanomedicine. 13: 6855-6870. PMID 30498347 DOI: 10.2147/IJN.S181928  0.4
2018 Xu L, Qiu HZ, Wu B, Lin GL, Lu JY, Zhang GN, Sun XY, Xiao Y. [Analysis of Clavien-Dindo classification and its prognosis factors of complications after laparoscopic right hemicolectomy]. Zhonghua Wai Ke Za Zhi [Chinese Journal of Surgery]. 56: 900-905. PMID 30497116  0.6
2018 Huang Y, Liu J, Yu L, Liu C, Wang J. Gonadal impairment and parental transfer of tris (2-butoxyethyl) phosphate in zebrafish after long-term exposure to environmentally relevant concentrations. Chemosphere. 218: 449-457. PMID 30497028 DOI: 10.1016/j.chemosphere.2018.11.139  0.88
2018 Wang H, Sun J, Tan Y, Li P, Xu X, Wang Y, Kong Q, Wang Y, Zhang B, Guo Y, Shi G, Shi J, Tan L. Anterior controllable antedisplacement and fusion as a revision surgery after posterior decompression surgery in patients with ossification of the posterior longitudinal ligament. World Neurosurgery. PMID 30496921 DOI: 10.1016/j.wneu.2018.11.156  0.6
2018 Coman EN, Wu HZ, Assari S. Exploring Causes of Depression and Anxiety Health Disparities (HD) by Examining Differences between 1:1 Matched Individuals. Brain Sciences. 8. PMID 30487396 DOI: 10.3390/brainsci8120207  0.32
2018 Lu H, Guo Z, Liu J, Zhang H, Zhao W, Wu Y, Ni J, Liu W, Tu J, Wang J, Ning X, Zhang J. Trends in stroke incidence among elderly low-income residents of rural China: a population-based study from 1992 to 2016. Aging. PMID 30487317 DOI: 10.18632/aging.101657  0.56
2018 Lu H, Cui X, Liu Z, Liu Y, Wang X, Zhou Z, Cai X, Zhang Z, Guo X, Hua J, Ma Z, Wang X, Zhang J, Zhang H, Liu F, et al. Discovery and annotation of a novel transposable element family in Gossypium. Bmc Plant Biology. 18: 307. PMID 30486783 DOI: 10.1186/s12870-018-1519-7  0.56
2018 Chen J, Tang YD, Zhou YS. [Association between thyroid nodule diameter measured by ultrasound and thyroid papillocarcinoma]. Zhonghua Yi Xue Za Zhi. 98: 3575-3578. PMID 30486572  0.52
2018 Yan Z, Du L, Lan X, Li Y, Wang W, Phillips DL. Time-Resolved Spectroscopic and Density Functional Theory Investigation of the Photogeneration of a Bifunctional Quinone Methide in Neutral and Basic Aqueous Solutions. Molecules (Basel, Switzerland). 23. PMID 30486443 DOI: 10.3390/molecules23123102  0.48
2018 Ouyang X, Li X, Lu W, Zhao X, Chen D. A Null -Ring Improves the Antioxidant Levels of Flavonol: A Comparative Study between Galangin and 3,5,7-Trihydroxychromone. Molecules (Basel, Switzerland). 23. PMID 30486289 DOI: 10.3390/molecules23123083  0.44
2018 Zhao ZX, Hua ZM, Li DW, Wei DS, Liu Y, Wang JG, Luo D, Wang HY. Effect of Sn Content on the Microstructure, Mechanical Properties and Corrosion Behavior of Biodegradable Mg⁻x (1, 3 and 5 wt.%) Sn⁻1Zn⁻0.5Ca Alloys. Materials (Basel, Switzerland). 11. PMID 30486280 DOI: 10.3390/ma11122378  0.48
2018 Jia N, Gu G, Zhao L, He S, Xiong F, Chai Y, Quan L, Hou H, Dai Y. Longitudinal study of breastfeeding and growth in 0-6 month infants. Asia Pacific Journal of Clinical Nutrition. 27: 1294-1301. PMID 30485929  0.4
2018 Lu P, Liu C, Li J, Man X, Liu H, Sun X, Liu F. Synthesis and Characteristics of New Organic Red Emissive Material Based on Phenanthro[9,10-d]imidazole. Chemistry, An Asian Journal. PMID 30485692 DOI: 10.1002/asia.201801578  0.68
2018 Tang C, Zhang W, Cai H, Ye Z, Zhang X, Tan W. Resveratrol improves ex vivo expansion of CB-CD34 cells via downregulating intracellular reactive oxygen species level. Journal of Cellular Biochemistry. PMID 30485505 DOI: 10.1002/jcb.28052  0.44
2018 Meng D, Chen H, Lin Y, Lin H, Hou C. Transferring of femoral nerve motor branches for high-level sciatic nerve injury: a cadaver feasibility study. Acta Neurochirurgica. PMID 30483983 DOI: 10.1007/s00701-018-3746-y  0.4
2018 Yang Z, Feng X, Zhang P, Chen T, Qiu H, Zhou Z, Li G, Tao KX, Li Y. Clinicopathological features and prognosis of 276 cases of primary small (≤ 2 cm) gastric gastrointestinal stromal tumors: a multicenter data review. Surgical Endoscopy. PMID 30483969 DOI: 10.1007/s00464-018-6564-7  0.36
2018 Zhang BF, Cheng ML, Lu S, Wu J, Wu YY, Liu Q, Zhao XK, Li YY, Hu YX, Liu W. [Effects of tenofovir and telbivudine on HBV RNA in pregnant women with different genotypes of HBeAg-positive hepatitis B in Guizhou Province]. Zhonghua Yi Xue Za Zhi. 98: 3503-3508. PMID 30481899  0.44
2018 Hu P, Shang J, Zhang WH, Gong GZ, Li YG, Chen XY, Jiang JN, Xie Q, Dou XG, Sun YT, Li YF, Liu YX, Liu GZ, Ma DW, Chi XL, et al. [HBsAg loss with Pegylated-interferon alfa-2a in hepatitis B patients with partial response to nucleos(t)-ide analog: new switch study]. Zhonghua Gan Zang Bing Za Zhi = Zhonghua Ganzangbing Zazhi = Chinese Journal of Hepatology. 26: 756-764. PMID 30481882  0.52
2018 Li J, Wang W, Zuo R, Zhou Y. The biomechanical stability before and after graft fusion with unilateral and bilateral pedicle screw fixation: a finite element study. World Neurosurgery. PMID 30481621 DOI: 10.1016/j.wneu.2018.11.141  0.52
2018 Zheng Y, Cai D, Huang B, Han J, Chen Q, Zhang J, Zhang J, Wang X, Shen H. Simultaneous detection of multiple hydroxylated polychlorinated biphenyls from biological samples using ultra-high performance liquid chromatography/isotope dilution tandem mass spectrometry. Journal of Separation Science. PMID 30481391 DOI: 10.1002/jssc.201800831  0.56
2018 Liu C, Wang C, Sun ZM. Conformational 2-Fold Interpenetrated Uranyl Supramolecular Isomers Based on (6,3) Sheet Topology: Structure, Luminescence, and Ion Exchange. Inorganic Chemistry. PMID 30481012 DOI: 10.1021/acs.inorgchem.8b02696  0.8
2018 Chen Y, Yang F, Yang J, Hou Y, He L, Hu H, Lv F. Aluminum (oxy) Hydroxide Nanorods Activate an Early Immune Response in Pseudomonas aeruginosa Vaccine. Acs Applied Materials & Interfaces. PMID 30480997 DOI: 10.1021/acsami.8b18164  0.6
2018 Wang Z, Wang X, Nishihara Y. Nickel-catalysed decarbonylative borylation of aroyl fluorides. Chemical Communications (Cambridge, England). PMID 30480276 DOI: 10.1039/c8cc08504h  0.48
2018 Guo JM, Lin HC, Ou P. [Prevalence of simple obesity and its high-risk factors in preschool children in Fuzhou, China]. Zhongguo Dang Dai Er Ke Za Zhi = Chinese Journal of Contemporary Pediatrics. 20: 943-938. PMID 30477626 DOI: 10.7499/j.issn.1008-8830.2018.11.011  0.32
2018 Liang SE, Hoffmann R, Peterson E, Soter NA. Use of Dapsone in the Treatment of Chronic Idiopathic and Autoimmune Urticaria. Jama Dermatology. PMID 30476976 DOI: 10.1001/jamadermatol.2018.3715  0.4
2018 Wang B, Wu B, Ran YN. A clinical study on mechanical ventilation PEEP setting for traumatic ARDS patients guided by esophageal pressure. Technology and Health Care : Official Journal of the European Society For Engineering and Medicine. PMID 30475777 DOI: 10.3233/THC-181380  0.68
2018 Kim JM, Seok OH, Ju S, Heo JE, Yeom J, Kim DS, Yoo JY, Varshavsky A, Lee C, Hwang CS. Formyl-methionine as an N-degron of a eukaryotic N-end rule pathway. Science (New York, N.Y.). PMID 30409808 DOI: 10.1126/science.aat0174  0.64
2018 Yan WQ, Xin YK, Jing Y, Li GF, Wang SM, Rong WC, Xiao G, Lei XB, Li B, Hu YC, Cui GB. Iodine Quantification Using Dual-Energy Computed Tomography for Differentiating Thymic Tumors. Journal of Computer Assisted Tomography. PMID 30339550 DOI: 10.1097/RCT.0000000000000800  0.4
2018 Yu G, Liu Y, Qin J, Wang Z, Hu Y, Wang F, Li Y, Chakrabarti S, Chen Q, Wang QK. Mechanistic insights into the interaction of the MOG1 protein with the cardiac sodium channel Na1.5 clarify the molecular basis of Brugada syndrome. The Journal of Biological Chemistry. PMID 30282806 DOI: 10.1074/jbc.RA118.003997  0.36
2018 Wang N, Zou Q, Xu J, Zhang J, Liu J. Ligand binding and heterodimerization with retinoid X receptor α (RXRα) induce farnesoid X receptor (FXR) conformational changes affecting co-activator binding. The Journal of Biological Chemistry. PMID 30275017 DOI: 10.1074/jbc.RA118.004652  0.76
2018 Zuo Y, Wang P, Sun J, Guo S, Wang G, Zuo T, Fan S, Zhou P, Liang M, Shi X, Wang X, Zhang L. Complementary recognition of the receptor binding site of highly pathogenic H5N1 influenza viruses by two human neutralizing antibodies. The Journal of Biological Chemistry. PMID 30154240 DOI: 10.1074/jbc.RA118.004604  0.52
2017 Oh JH, Chen SJ, Varshavsky A. A reference-based protein degradation assay without global translation inhibitors. The Journal of Biological Chemistry. PMID 29122887 DOI: 10.1074/jbc.M117.814236  0.72
2017 Oh JH, Hyun JY, Varshavsky A. Control of Hsp90 chaperone and its clients by N-terminal acetylation and the N-end rule pathway. Proceedings of the National Academy of Sciences of the United States of America. PMID 28515311 DOI: 10.1073/pnas.1705898114  0.64
2017 Chen SJ, Wu X, Wadas B, Oh JH, Varshavsky A. An N-end rule pathway that recognizes proline and destroys gluconeogenic enzymes. Science (New York, N.Y.). 355. PMID 28126757 DOI: 10.1126/science.aal3655  0.72
2016 Yang N, Cui J, Zhang L, Xiao W, Alshawabkeh AN, Mao X. Iron electrolysis-assisted peroxymonosulfate chemical oxidation for the remediation of chlorophenol-contaminated groundwater. Journal of Chemical Technology and Biotechnology (Oxford, Oxfordshire : 1986). 91: 938-947. PMID 30473593 DOI: 10.1002/jctb.4659  0.4
2016 Wadas B, Piatkov K, Brower C, Varshavsky A. Analyzing N-terminal Arginylation Through the Use of Peptide Arrays and Degradation Assays. The Journal of Biological Chemistry. PMID 27510035 DOI: 10.1074/jbc.M116.747956  1
2016 Wadas B, Borjigin J, Huang Z, Oh JH, Hwang CS, Varshavsky A. Degradation of Serotonin N-Acetyltransferase, a Circadian Regulator, by the N-end Rule Pathway. The Journal of Biological Chemistry. PMID 27339900 DOI: 10.1074/jbc.M116.734640  0.64
2016 Liu YJ, Liu C, Chang Z, Wadas B, Brower CS, Song ZH, Xu ZL, Shang YL, Liu WX, Wang LN, Dong W, Varshavsky A, Hu RG, Li W. Degradation of the Separase-cleaved Rec8, a Meiotic Cohesin Subunit, by the N-end Rule Pathway. The Journal of Biological Chemistry. PMID 26858254 DOI: 10.1074/jbc.M116.714964  1
2015 Piatkov KI, Vu TT, Hwang CS, Varshavsky A. Formyl-methionine as a degradation signal at the N-termini of bacterial proteins. Microbial Cell. 2: 376-393. PMID 26866044 DOI: 10.15698/mic2015.10.231  0.64
2015 Park SE, Kim JM, Seok OH, Cho H, Wadas B, Kim SY, Varshavsky A, Hwang CS. Control of mammalian G protein signaling by N-terminal acetylation and the N-end rule pathway. Science (New York, N.Y.). 347: 1249-52. PMID 25766235 DOI: 10.1126/science.aaa3844  1
2014 Brower CS, Rosen CE, Jones RH, Wadas BC, Piatkov KI, Varshavsky A. Liat1, an arginyltransferase-binding protein whose evolution among primates involved changes in the numbers of its 10-residue repeats. Proceedings of the National Academy of Sciences of the United States of America. 111: E4936-45. PMID 25369936 DOI: 10.1073/pnas.1419587111  1
2014 Varshavsky A. Discovery of the biology of the ubiquitin system. Jama. 311: 1969-70. PMID 24846030 DOI: 10.1001/jama.2014.5549  1
2014 Piatkov KI, Oh JH, Liu Y, Varshavsky A. Calpain-generated natural protein fragments as short-lived substrates of the N-end rule pathway. Proceedings of the National Academy of Sciences of the United States of America. 111: E817-26. PMID 24550490 DOI: 10.1073/pnas.1401639111  1
2014 Kim HK, Kim RR, Oh JH, Cho H, Varshavsky A, Hwang CS. The N-terminal methionine of cellular proteins as a degradation signal. Cell. 156: 158-69. PMID 24361105 DOI: 10.1016/j.cell.2013.11.031  1
2013 Piatkov K, Graciet E, Varshavsky A. Ubiquitin reference technique and its use in ubiquitin-lacking prokaryotes. Plos One. 8: e67952. PMID 23825692 DOI: 10.1371/journal.pone.0067952  1
2013 Shemorry A, Hwang CS, Varshavsky A. Control of protein quality and stoichiometries by N-terminal acetylation and the N-end rule pathway. Molecular Cell. 50: 540-51. PMID 23603116 DOI: 10.1016/j.molcel.2013.03.018  1
2013 Brower CS, Piatkov KI, Varshavsky A. Neurodegeneration-associated protein fragments as short-lived substrates of the N-end rule pathway. Molecular Cell. 50: 161-71. PMID 23499006 DOI: 10.1016/j.molcel.2013.02.009  1
2013 Bao X, Fan S, Varshavsky A, Li KA, Choudhury RR. Your reactions suggest you liked the movie: Automatic content rating via reaction sensing Ubicomp 2013 - Proceedings of the 2013 Acm International Joint Conference On Pervasive and Ubiquitous Computing. 197-206. DOI: 10.1145/2493432.2493440  0.36
2013 Becker R, Ramón C, Hanson K, Isaacman S, Loh JM, Martonosi M, Rowland J, Urbanek S, Varshavsky A, Volinsky C. Human mobility characterization from cellular network data Communications of the Acm. 56: 74-82. DOI: 10.1145/2398356.2398375  0.36
2013 Schmidt A, Liu J, Roussos G, Varshavsky A. Editorial Pervasive and Mobile Computing. 9: 337-338. DOI: 10.1016/j.pmcj.2013.03.002  0.36
2013 Agarwal S, Varshavsky A. Message from the chairs Acm Hotmobile 2013: the 14th Workshop On Mobile Computing Systems and Applications 0.36
2012 Piatkov KI, Colnaghi L, Békés M, Varshavsky A, Huang TT. The auto-generated fragment of the Usp1 deubiquitylase is a physiological substrate of the N-end rule pathway. Molecular Cell. 48: 926-33. PMID 23159736 DOI: 10.1016/j.molcel.2012.10.012  1
2012 Varshavsky A. Augmented generation of protein fragments during wakefulness as the molecular cause of sleep: a hypothesis. Protein Science : a Publication of the Protein Society. 21: 1634-61. PMID 22930402 DOI: 10.1002/pro.2148  1
2012 Piatkov KI, Brower CS, Varshavsky A. The N-end rule pathway counteracts cell death by destroying proapoptotic protein fragments. Proceedings of the National Academy of Sciences of the United States of America. 109: E1839-47. PMID 22670058 DOI: 10.1073/pnas.1207786109  1
2012 Varshavsky A. The ubiquitin system, an immense realm. Annual Review of Biochemistry. 81: 167-76. PMID 22663079 DOI: 10.1146/annurev-biochem-051910-094049  1
2012 Varshavsky A. Three decades of studies to understand the functions of the ubiquitin family. Methods in Molecular Biology (Clifton, N.J.). 832: 1-11. PMID 22350874 DOI: 10.1007/978-1-61779-474-2_1  1
2012 Gember A, Akella A, Pang J, Varshavsky A, Caceres R. Obtaining in-context measurements of cellular network performance Proceedings of the Acm Sigcomm Internet Measurement Conference, Imc. 287-300. DOI: 10.1145/2398776.2398807  0.36
2012 Miluzzo E, Varshavsky A, Balakrishnan S, Choudhury RR. Tapprints: Your finger taps have fingerprints Mobisys'12 - Proceedings of the 10th International Conference On Mobile Systems, Applications, and Services. 323-336. DOI: 10.1145/2307636.2307666  0.36
2012 Isaacman S, Becker R, Cáceres R, Martonosi M, Rowland J, Varshavsky A, Willinger W. Human mobility modeling at metropolitan scales Mobisys'12 - Proceedings of the 10th International Conference On Mobile Systems, Applications, and Services. 239-251. DOI: 10.1145/2307636.2307659  0.36
2012 Schmidt A, Liu J, Roussos G, Varshavsky A. Welcome from the technical program chairs 2012 Ieee International Conference On Pervasive Computing and Communications, Percom 2012. iv. DOI: 10.1109/PerCom.2012.6199839  0.36
2012 Dyaberi JM, Parsons B, Pai V, Kannan K, Chen YF, Jana R, Stern D, Varshavsky A. Managing cellular congestion using incentives Ieee Communications Magazine. 50: 100-107. DOI: 10.1109/MCOM.2012.6353689  0.36
2011 Hwang CS, Sukalo M, Batygin O, Addor MC, Brunner H, Aytes AP, Mayerle J, Song HK, Varshavsky A, Zenker M. Ubiquitin ligases of the N-end rule pathway: assessment of mutations in UBR1 that cause the Johanson-Blizzard syndrome. Plos One. 6: e24925. PMID 21931868 DOI: 10.1371/journal.pone.0024925  1
2011 Varshavsky A. The N-end rule pathway and regulation by proteolysis. Protein Science : a Publication of the Protein Society. 20: 1298-345. PMID 21633985 DOI: 10.1002/pro.666  1
2011 Lagar-Cavilla HA, Joshi K, Varshavsky A, Bickford J, Parra D. Traffic backfilling: Subsidizing lunch for delay-tolerant applications in UMTS networks Proceedings of the 3rd Acm Sosp Workshop On Networking, Systems, and Applications On Mobile Handhelds, Mobiheld'11. DOI: 10.1145/2043106.2043117  0.36
2011 Javed U, Han D, Caceres R, Pang J, Seshan S, Varshavsky A. Predicting handoffs in 3G networks Proceedings of the 3rd Acm Sosp Workshop On Networking, Systems, and Applications On Mobile Handhelds, Mobiheld'11. DOI: 10.1145/2043106.2043114  0.36
2011 Becker RA, Caceres R, Hanson K, Loh JM, Urbanek S, Varshavsky A, Volinsky C. Route classification using cellular handoff patterns Ubicomp'11 - Proceedings of the 2011 Acm Conference On Ubiquitous Computing. 123-132. DOI: 10.1145/2030112.2030130  0.36
2011 Bickford J, Lagar-Cavilla HA, Varshavsky A, Ganapathy V, Iftode L. Security versus energy tradeoffs in host-based mobile malware detection Mobisys'11 - Compilation Proceedings of the 9th International Conference On Mobile Systems, Applications and Services and Co-Located Workshops. 225-238. DOI: 10.1145/1999995.2000017  0.36
2011 Mathur S, Miller R, Varshavsky A, Trappe W, Mandayam N. ProxiMate: Proximity-based secure pairing using ambient wireless signals Mobisys'11 - Compilation Proceedings of the 9th International Conference On Mobile Systems, Applications and Services and Co-Located Workshops. 211-224. DOI: 10.1145/1999995.2000016  0.36
2011 Isaacman S, Becker R, Caceres R, Kobourov S, Martonosi M, Rowland J, Varshavsky A. Ranges of human mobility in Los Angeles and New York 2011 Ieee International Conference On Pervasive Computing and Communications Workshops, Percom Workshops 2011. 88-93. DOI: 10.1109/PERCOMW.2011.5766977  0.36
2011 Chandrasekaran G, Vu T, Varshavsky A, Gruteser M, Martin RP, Yang J, Chen Y. Tracking vehicular speed variations by warping mobile phone signal strengths 2011 Ieee International Conference On Pervasive Computing and Communications, Percom 2011. 213-221. DOI: 10.1109/PERCOM.2011.5767589  0.36
2011 Becker RA, Cáceres R, Hanson K, Loh JM, Urbanek S, Varshavsky A, Volinsky C. A tale of one city: Using cellular network data for urban planning Ieee Pervasive Computing. 10: 18-26. DOI: 10.1109/MPRV.2011.44  0.36
2011 Shakimov A, Lim H, Cáceres R, Cox LP, Li K, Liu D, Varshavsky A. Vis-à-Vis: Privacy-preserving online social networking via Virtual Individual Servers 2011 3rd International Conference On Communication Systems and Networks, Comsnets 2011. DOI: 10.1109/COMSNETS.2011.5716497  0.36
2011 Liu D, Shakimov A, Cáceres R, Varshavsky A, Cox LP. Confidant: Protecting OSN data without locking it up Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 7049: 61-80. DOI: 10.1007/978-3-642-25821-3_4  0.36
2011 Isaacman S, Becker R, Cáceres R, Kobourov S, Martonosi M, Rowland J, Varshavsky A. Identifying important places in people's lives from cellular network data Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 6696: 133-151. DOI: 10.1007/978-3-642-21726-5_9  0.36
2010 Hwang CS, Shemorry A, Auerbach D, Varshavsky A. The N-end rule pathway is mediated by a complex of the RING-type Ubr1 and HECT-type Ufd4 ubiquitin ligases. Nature Cell Biology. 12: 1177-85. PMID 21076411 DOI: 10.1038/ncb2121  1
2010 Brower CS, Veiga L, Jones RH, Varshavsky A. Mouse Dfa is a repressor of TATA-box promoters and interacts with the Abt1 activator of basal transcription. The Journal of Biological Chemistry. 285: 17218-34. PMID 20356838 DOI: 10.1074/jbc.M110.118638  1
2010 Hwang CS, Shemorry A, Varshavsky A. N-terminal acetylation of cellular proteins creates specific degradation signals. Science (New York, N.Y.). 327: 973-7. PMID 20110468 DOI: 10.1126/science.1183147  1
2010 Chandrasekaran G, Vu T, Varshavsky A, Gruteser M, Martin RP, Yang J, Chen Y. Vehicular speed estimation using received signal strength from mobile phones Ubicomp'10 - Proceedings of the 2010 Acm Conference On Ubiquitous Computing. 237-240. DOI: 10.1145/1864349.1864386  0.36
2010 Yang J, Varshavsky A, Liu H, Chen Y, Gruteser M. Accuracy characterization of cell tower localization Ubicomp'10 - Proceedings of the 2010 Acm Conference On Ubiquitous Computing. 223-226. DOI: 10.1145/1864349.1864384  0.36
2010 Isaacman S, Becker R, Cáceres R, Kobourov S, Rowland J, Varshavsky A. A tale of two cities Hotmobile 2010: the 11th Workshop On Mobile Computing Systems and Applications. 19-24. DOI: 10.1145/1734583.1734589  0.36
2009 Brower CS, Varshavsky A. Ablation of arginylation in the mouse N-end rule pathway: loss of fat, higher metabolic rate, damaged spermatogenesis, and neurological perturbations. Plos One. 4: e7757. PMID 19915679 DOI: 10.1371/journal.pone.0007757  1
2009 Graciet E, Walter F, Ó'Maoiléidigh DS, Pollmann S, Meyerowitz EM, Varshavsky A, Wellmer F. The N-end rule pathway controls multiple functions during Arabidopsis shoot and leaf development. Proceedings of the National Academy of Sciences of the United States of America. 106: 13618-23. PMID 19620738 DOI: 10.1073/pnas.0906404106  1
2009 Wang H, Piatkov KI, Brower CS, Varshavsky A. Glutamine-specific N-terminal amidase, a component of the N-end rule pathway. Molecular Cell. 34: 686-95. PMID 19560421 DOI: 10.1016/j.molcel.2009.04.032  1
2009 Hwang CS, Shemorry A, Varshavsky A. Two proteolytic pathways regulate DNA repair by cotargeting the Mgt1 alkylguanine transferase. Proceedings of the National Academy of Sciences of the United States of America. 106: 2142-7. PMID 19164530 DOI: 10.1073/pnas.0812316106  1
2009 Scannell A, Varshavsky A, LaMarca A, de Lara E. Proximity-based authentication of mobile devices International Journal of Security and Networks. 4: 4-16. DOI: 10.1504/IJSN.2009.023422  0.36
2008 Varshavsky A. The N-end rule at atomic resolution. Nature Structural & Molecular Biology. 15: 1238-40. PMID 19050717 DOI: 10.1038/nsmb1208-1238  1
2008 Hwang CS, Varshavsky A. Regulation of peptide import through phosphorylation of Ubr1, the ubiquitin ligase of the N-end rule pathway. Proceedings of the National Academy of Sciences of the United States of America. 105: 19188-93. PMID 19033468 DOI: 10.1073/pnas.0808891105  1
2008 Xia Z, Turner GC, Hwang CS, Byrd C, Varshavsky A. Amino acids induce peptide uptake via accelerated degradation of CUP9, the transcriptional repressor of the PTR2 peptide transporter. The Journal of Biological Chemistry. 283: 28958-68. PMID 18708352 DOI: 10.1074/jbc.M803980200  1
2008 Varshavsky A. Discovery of cellular regulation by protein degradation. The Journal of Biological Chemistry. 283: 34469-89. PMID 18708349 DOI: 10.1074/jbc.X800009200  1
2008 Xia Z, Webster A, Du F, Piatkov K, Ghislain M, Varshavsky A. Substrate-binding sites of UBR1, the ubiquitin ligase of the N-end rule pathway. The Journal of Biological Chemistry. 283: 24011-28. PMID 18566452 DOI: 10.1074/jbc.M802583200  1
2008 Connor RE, Piatkov K, Varshavsky A, Tirrell DA. Enzymatic N-terminal addition of noncanonical amino acids to peptides and proteins. Chembiochem : a European Journal of Chemical Biology. 9: 366-9. PMID 18203209 DOI: 10.1002/cbic.200700605  1
2008 Hu RG, Wang H, Xia Z, Varshavsky A. The N-end rule pathway is a sensor of heme. Proceedings of the National Academy of Sciences of the United States of America. 105: 76-81. PMID 18162538 DOI: 10.1073/pnas.0710568105  1
2008 Varshavsky A, Pankratov D, Krumm J, De Lara E. Calibree: Calibration-free localization using relative distance estimations Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 5013: 146-161. DOI: 10.1007/978-3-540-79576-6_9  0.36
2007 Varshavsky A. Targeting the absence: homozygous DNA deletions as immutable signposts for cancer therapy. Proceedings of the National Academy of Sciences of the United States of America. 104: 14935-40. PMID 17846424 DOI: 10.1073/pnas.0706546104  1
2007 Schnupf P, Zhou J, Varshavsky A, Portnoy DA. Listeriolysin O secreted by Listeria monocytogenes into the host cell cytosol is degraded by the N-end rule pathway. Infection and Immunity. 75: 5135-47. PMID 17682039 DOI: 10.1128/IAI.00164-07  1
2007 Tasaki T, Sohr R, Xia Z, Hellweg R, Hörtnagl H, Varshavsky A, Kwon YT. Biochemical and genetic studies of UBR3, a ubiquitin ligase with a function in olfactory and other sensory systems. The Journal of Biological Chemistry. 282: 18510-20. PMID 17462990 DOI: 10.1074/jbc.M701894200  1
2007 Varshavsky A, Lamarca A, De Lara E. Enabling secure and spontaneous communication between mobile devices using common radio environment Proceedings - 8th Ieee Workshop On Mobile Computing Systems and Applications, Hotmobile 2007. 9-13. DOI: 10.1109/WMCSA.2007.4389551  0.36
2007 Varshavsky A, de Lara E, Hightower J, LaMarca A, Otsason V. GSM indoor localization Pervasive and Mobile Computing. 3: 698-720. DOI: 10.1016/j.pmcj.2007.07.004  0.36
2007 Varshavsky A, Scannell A, LaMarca A, De Lara E. Amigo: Proximity-based authentication of mobile devices Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 4717: 253-270.  0.36
2007 Dearman D, Varshavsky A, De Lara E, Truong KN. An exploration of location error estimation Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 4717: 181-198.  0.36
2006 Varshavsky A. Discovering the RNA double helix and hybridization. Cell. 127: 1295-7. PMID 17190591 DOI: 10.1016/j.cell.2006.12.008  1
2006 Hu RG, Brower CS, Wang H, Davydov IV, Sheng J, Zhou J, Kwon YT, Varshavsky A. Arginyltransferase, its specificity, putative substrates, bidirectional promoter, and splicing-derived isoforms. The Journal of Biological Chemistry. 281: 32559-73. PMID 16943202 DOI: 10.1074/jbc.M604355200  1
2006 An JY, Seo JW, Tasaki T, Lee MJ, Varshavsky A, Kwon YT. Impaired neurogenesis and cardiovascular development in mice lacking the E3 ubiquitin ligases UBR1 and UBR2 of the N-end rule pathway. Proceedings of the National Academy of Sciences of the United States of America. 103: 6212-7. PMID 16606826 DOI: 10.1073/pnas.0601700103  1
2006 Varshavsky A. The early history of the ubiquitin field. Protein Science : a Publication of the Protein Society. 15: 647-54. PMID 16501229 DOI: 10.1110/ps.052012306  1
2006 Graciet E, Hu RG, Piatkov K, Rhee JH, Schwarz EM, Varshavsky A. Aminoacyl-transferases and the N-end rule pathway of prokaryotic/eukaryotic specificity in a human pathogen. Proceedings of the National Academy of Sciences of the United States of America. 103: 3078-83. PMID 16492767 DOI: 10.1073/pnas.0511224103  1
2006 Varshavsky A. The origins of the ubiquitin field Israel Journal of Chemistry. 46: 137-144. DOI: 10.1560/5E71-3UU5-1NH2-6UYJ  1
2006 Varshavsky A, Lamarca A, Hightower J, De Lara E. The skyLoc floor localization system Proceedings - Fifth Annual Ieee International Conference On Pervasive Computing and Communications, Percom 2007. 125-134. DOI: 10.1109/PERCOM.2007.37  0.36
2006 Chen MY, Sohn T, Chmelev D, Haehnel D, Hightower J, Hughes J, LaMarca A, Potter F, Smith L, Varshavsky A. Practical metropolitan-scale positioning for GSM phones Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 4206: 225-242.  0.36
2006 Sohn T, Varshavsky A, LaMarca A, Chen MY, Choudhury T, Smith I, Consolvo S, Hightower J, Griswold WG, De Lara E. Mobility detection using everyday GSM traces Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 4206: 212-224.  0.36
2005 Dohmen RJ, Varshavsky A. Heat-inducible degron and the making of conditional mutants. Methods in Enzymology. 399: 799-822. PMID 16338396 DOI: 10.1016/S0076-6879(05)99052-6  1
2005 Varshavsky A. Ubiquitin fusion technique and related methods. Methods in Enzymology. 399: 777-99. PMID 16338395 DOI: 10.1016/S0076-6879(05)99051-4  1
2005 Zenker M, Mayerle J, Lerch MM, Tagariello A, Zerres K, Durie PR, Beier M, Hülskamp G, Guzman C, Rehder H, Beemer FA, Hamel B, Vanlieferinghen P, Gershoni-Baruch R, Vieira MW, ... ... Varshavsky A, et al. Deficiency of UBR1, a ubiquitin ligase of the N-end rule pathway, causes pancreatic dysfunction, malformations and mental retardation (Johanson-Blizzard syndrome). Nature Genetics. 37: 1345-50. PMID 16311597 DOI: 10.1038/ng1681  1
2005 Hu RG, Sheng J, Qi X, Xu Z, Takahashi TT, Varshavsky A. The N-end rule pathway as a nitric oxide sensor controlling the levels of multiple regulators. Nature. 437: 981-6. PMID 16222293 DOI: 10.1038/nature04027  1
2005 Tasaki T, Mulder LC, Iwamatsu A, Lee MJ, Davydov IV, Varshavsky A, Muesing M, Kwon YT. A family of mammalian E3 ubiquitin ligases that contain the UBR box motif and recognize N-degrons. Molecular and Cellular Biology. 25: 7120-36. PMID 16055722 DOI: 10.1128/MCB.25.16.7120-7136.2005  1
2005 Varshavsky A. Regulated protein degradation. Trends in Biochemical Sciences. 30: 283-6. PMID 15950869 DOI: 10.1016/j.tibs.2005.04.005  1
2005 Varshavsky A, Reid B, De Lara E. A cross-layer approach to service discovery and selection in MANETs 2nd Ieee International Conference On Mobile Ad-Hoc and Sensor Systems, Mass 2005. 2005: 459-466. DOI: 10.1109/MAHSS.2005.1542832  0.36
2005 Otsason V, Varshavsky A, LaMarca A, De Lara E. Accurate GSM indoor localization Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 3660: 141-158.  0.36
2004 Yin J, Kwon YT, Varshavsky A, Wang W. RECQL4, mutated in the Rothmund-Thomson and RAPADILINO syndromes, interacts with ubiquitin ligases UBR1 and UBR2 of the N-end rule pathway. Human Molecular Genetics. 13: 2421-30. PMID 15317757 DOI: 10.1093/hmg/ddh269  1
2004 Finley D, Ciechanover A, Varshavsky A. Ubiquitin as a central cellular regulator. Cell. 116: S29-32, 2 p followin. PMID 15055578  1
2004 Varshavsky A. 'Spalog' and 'sequelog': neutral terms for spatial and sequence similarity. Current Biology : Cb. 14: R181-3. PMID 15028230 DOI: 10.1016/j.cub.2004.02.014  1
2004 Varshavsky A, De Lara E. Alleviating self-interference in MANETs Proceedings - Conference On Local Computer Networks, Lcn. 642-649. DOI: 10.1109/LCN.2004.14  0.36
2004 Varshavsky A, Li B, De Lara E. Cross-layer flow control in lightly-loaded multi-hop ad hoc networks Proceedings of the International Conference On Parallel Processing Workshops. 315-321. DOI: 10.1109/ICPPW.2004.1328033  0.36
2003 Kwon YT, Xia Z, An JY, Tasaki T, Davydov IV, Seo JW, Sheng J, Xie Y, Varshavsky A. Female lethality and apoptosis of spermatocytes in mice lacking the UBR2 ubiquitin ligase of the N-end rule pathway. Molecular and Cellular Biology. 23: 8255-71. PMID 14585983 DOI: 10.1128/MCB.23.22.8255-8271.2003  1
2003 Varshavsky A. Q & A: Alexander Varshavsky. Current Biology : Cb. 13: R501-2. PMID 12842020  1
2003 Varshavsky A. The N-end rule and regulation of apoptosis. Nature Cell Biology. 5: 373-6. PMID 12724766 DOI: 10.1038/ncb0503-373  1
2002 Xie Y, Varshavsky A. UFD4 lacking the proteasome-binding region catalyses ubiquitination but is impaired in proteolysis. Nature Cell Biology. 4: 1003-7. PMID 12447385 DOI: 10.1038/ncb889  1
2002 Sheng J, Kumagai A, Dunphy WG, Varshavsky A. Dissection of c-MOS degron. The Embo Journal. 21: 6061-71. PMID 12426378 DOI: 10.1093/emboj/cdf626  1
2002 Du F, Navarro-Garcia F, Xia Z, Tasaki T, Varshavsky A. Pairs of dipeptides synergistically activate the binding of substrate by ubiquitin ligase through dissociation of its autoinhibitory domain. Proceedings of the National Academy of Sciences of the United States of America. 99: 14110-5. PMID 12391316 DOI: 10.1073/pnas.172527399  1
2002 Kwon YT, Kashina AS, Davydov IV, Hu RG, An JY, Seo JW, Du F, Varshavsky A. An essential role of N-terminal arginylation in cardiovascular development. Science (New York, N.Y.). 297: 96-9. PMID 12098698 DOI: 10.1126/science.1069531  1
2001 Kwon YT, Xia Z, Davydov IV, Lecker SH, Varshavsky A. Construction and analysis of mouse strains lacking the ubiquitin ligase UBR1 (E3alpha) of the N-end rule pathway. Molecular and Cellular Biology. 21: 8007-21. PMID 11689692 DOI: 10.1128/MCB.21.23.8007-8021.2001  1
2001 Varshavsky A. The 2000 Genetics Society of America Medal. Jack W. Szostak. Genetics. 157: 465-6. PMID 11370622  1
2001 Rao H, Uhlmann F, Nasmyth K, Varshavsky A. Degradation of a cohesin subunit by the N-end rule pathway is essential for chromosome stability. Nature. 410: 955-9. PMID 11309624 DOI: 10.1038/35073627  1
2001 Xie Y, Varshavsky A. RPN4 is a ligand, substrate, and transcriptional regulator of the 26S proteasome: a negative feedback circuit. Proceedings of the National Academy of Sciences of the United States of America. 98: 3056-61. PMID 11248031 DOI: 10.1073/pnas.071022298  1
2000 Varshavsky A. Recent studies of the ubiquitin system and the N-end rule pathway. Harvey Lectures. 96: 93-116. PMID 12200873  1
2000 Varshavsky A, Turner G, Du F, Xie Y. Felix Hoppe-Seyler Lecture 2000. The ubiquitin system and the N-end rule pathway. Biological Chemistry. 381: 779-89. PMID 11076011 DOI: 10.1515/BC.2000.101  1
2000 Varshavsky A. Ubiquitin fusion technique and its descendants. Methods in Enzymology. 327: 578-93. PMID 11045010 DOI: 10.1016/S0076-6879(00)27303-5  1
2000 Hershko A, Ciechanover A, Varshavsky A. Basic Medical Research Award. The ubiquitin system. Nature Medicine. 6: 1073-81. PMID 11017125 DOI: 10.1038/80384  1
2000 Turner GC, Varshavsky A. Detecting and measuring cotranslational protein degradation in vivo. Science (New York, N.Y.). 289: 2117-20. PMID 11000112 DOI: 10.1126/science.289.5487.2117  1
2000 Turner GC, Du F, Varshavsky A. Peptides accelerate their uptake by activating a ubiquitin-dependent proteolytic pathway. Nature. 405: 579-83. PMID 10850718 DOI: 10.1038/35014629  1
2000 Kwon YT, Balogh SA, Davydov IV, Kashina AS, Yoon JK, Xie Y, Gaur A, Hyde L, Denenberg VH, Varshavsky A. Altered activity, social behavior, and spatial memory in mice lacking the NTAN1p amidase and the asparagine branch of the N-end rule pathway. Molecular and Cellular Biology. 20: 4135-48. PMID 10805755 DOI: 10.1128/MCB.20.11.4135-4148.2000  1
2000 Davydov IV, Varshavsky A. RGS4 is arginylated and degraded by the N-end rule pathway in vitro. The Journal of Biological Chemistry. 275: 22931-41. PMID 10783390 DOI: 10.1074/jbc.M001605200  1
2000 Xie Y, Varshavsky A. Physical association of ubiquitin ligases and the 26S proteasome. Proceedings of the National Academy of Sciences of the United States of America. 97: 2497-502. PMID 10688918 DOI: 10.1073/pnas.060025497  1
2000 Varshavsky AD, Birnbaum DT, Beals JM, Saxberg BE. Global stochastic optimization in hierarchical modeling of ligand/protein binding profiles Kybernetes. 29: 452-472. DOI: 10.1108/03684920010322217  0.36
1999 Xie Y, Varshavsky A. The E2-E3 interaction in the N-end rule pathway: the RING-H2 finger of E3 is required for the synthesis of multiubiquitin chain. The Embo Journal. 18: 6832-44. PMID 10581257 DOI: 10.1093/emboj/18.23.6832  1
1999 Suzuki T, Varshavsky A. Degradation signals in the lysine-asparagine sequence space. The Embo Journal. 18: 6017-26. PMID 10545113 DOI: 10.1093/emboj/18.21.6017  1
1999 Xie Y, Varshavsky A. The N-end rule pathway is required for import of histidine in yeast lacking the kinesin-like protein Cin8p. Current Genetics. 36: 113-23. PMID 10501933 DOI: 10.1007/s002940050480  1
1999 Kwon YT, Lévy F, Varshavsky A. Bivalent inhibitor of the N-end rule pathway. The Journal of Biological Chemistry. 274: 18135-9. PMID 10364269 DOI: 10.1074/jbc.274.25.18135  1
1999 Dünnwald M, Varshavsky A, Johnsson N. Detection of transient in vivo interactions between substrate and transporter during protein translocation into the endoplasmic reticulum. Molecular Biology of the Cell. 10: 329-44. PMID 9950680  1
1999 Lévy F, Johnston JA, Varshavsky A. Analysis of a conditional degradation signal in yeast and mammalian cells. European Journal of Biochemistry / Febs. 259: 244-52. PMID 9914499 DOI: 10.1046/j.1432-1327.1999.00024.x  1
1999 Kwon YT, Kashina AS, Varshavsky A. Alternative splicing results in differential expression, activity, and localization of the two forms of arginyl-tRNA-protein transferase, a component of the N-end rule pathway. Molecular and Cellular Biology. 19: 182-93. PMID 9858543  1
1998 Davydov IV, Patra D, Varshavsky A. The N-end rule pathway in Xenopus egg extracts. Archives of Biochemistry and Biophysics. 357: 317-25. PMID 9735173 DOI: 10.1006/abbi.1998.0829  1
1998 Finley D, Tanaka K, Mann C, Feldmann H, Hochstrasser M, Vierstra R, Johnston S, Hampton R, Haber J, Mccusker J, Silver P, Frontali L, Thorsness P, Varshavsky A, Byers B, et al. Unified nomenclature for subunits of the Saccharomyces cerevisiae proteasome regulatory particle. Trends in Biochemical Sciences. 23: 244-5. PMID 9697412 DOI: 10.1016/S0968-0004(98)01222-5  1
1998 Kwon YT, Reiss Y, Fried VA, Hershko A, Yoon JK, Gonda DK, Sangan P, Copeland NG, Jenkins NA, Varshavsky A. The mouse and human genes encoding the recognition component of the N-end rule pathway. Proceedings of the National Academy of Sciences of the United States of America. 95: 7898-903. PMID 9653112 DOI: 10.1073/pnas.95.14.7898  1
1998 Ramos PC, Höckendorff J, Johnson ES, Varshavsky A, Dohmen RJ. Ump1p is required for proper maturation of the 20S proteasome and becomes its substrate upon completion of the assembly. Cell. 92: 489-99. PMID 9491890 DOI: 10.1016/S0092-8674(00)80942-3  1
1998 Varshavsky A. Codominant interference, antieffectors, and multitarget drugs. Proceedings of the National Academy of Sciences of the United States of America. 95: 2094-9. PMID 9482844 DOI: 10.1073/pnas.95.5.2094  1
1998 Byrd C, Turner GC, Varshavsky A. The N-end rule pathway controls the import of peptides through degradation of a transcriptional repressor. The Embo Journal. 17: 269-77. PMID 9427760 DOI: 10.1093/emboj/17.1.269  1
1997 Varshavsky A. The ubiquitin system. Trends in Biochemical Sciences. 22: 383-7. PMID 9357313 DOI: 10.1016/S0968-0004(97)01122-5  1
1997 Varshavsky A. The N-end rule pathway of protein degradation. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. 2: 13-28. PMID 9112437  1
1997 Varshavsky A, Byrd C, Kwon YT. Recent studies of the n-end rule pathway Faseb Journal. 11: A995.  1
1996 Grigoryev S, Stewart AE, Kwon YT, Arfin SM, Bradshaw RA, Jenkins NA, Copeland NG, Varshavsky A. A mouse amidase specific for N-terminal asparagine. The gene, the enzyme, and their function in the N-end rule pathway. The Journal of Biological Chemistry. 271: 28521-32. PMID 8910481 DOI: 10.1074/jbc.271.45.28521  1
1996 Varshavsky A. The N-end rule: functions, mysteries, uses. Proceedings of the National Academy of Sciences of the United States of America. 93: 12142-9. PMID 8901547 DOI: 10.1073/pnas.93.22.12142  1
1996 Ghislain M, Dohmen RJ, Levy F, Varshavsky A. Cdc48p interacts with Ufd3p, a WD repeat protein required for ubiquitin-mediated proteolysis in Saccharomyces cerevisiae. The Embo Journal. 15: 4884-99. PMID 8890162  1
1996 Lévy F, Johnsson N, Rümenapf T, Varshavsky A. Using ubiquitin to follow the metabolic fate of a protein. Proceedings of the National Academy of Sciences of the United States of America. 93: 4907-12. PMID 8643502 DOI: 10.1073/pnas.93.10.4907  1
1996 Birnbaum DT, Dodd SW, Saxberg BE, Varshavsky AD, Beals JM. Hierarchical modeling of phenolic ligand binding to 2Zn--insulin hexamers. Biochemistry. 35: 5366-78. PMID 8611526 DOI: 10.1021/bi9600557  0.36
1995 Varshavsky A. The N-end rule. Cold Spring Harbor Symposia On Quantitative Biology. 60: 461-78. PMID 8824420  1
1995 Herron DK, Bollinger NG, Chaney MO, Varshavsky AD, Yost JB, Sherman WR, Thingvold JA. Visualization and comparison of molecular dynamics simulations of leukotriene C4, leukotriene D4, and leukotriene E4. Journal of Molecular Graphics. 13: 337-41. PMID 8820302 DOI: 10.1016/0263-7855(95)00081-X  0.36
1995 Baker RT, Varshavsky A. Yeast N-terminal amidase. A new enzyme and component of the N-end rule pathway. The Journal of Biological Chemistry. 270: 12065-74. PMID 7744855 DOI: 10.1074/jbc.270.20.12065  1
1995 Varshavsky A. Codominance and toxins: a path to drugs of nearly unlimited selectivity. Proceedings of the National Academy of Sciences of the United States of America. 92: 3663-7. PMID 7731961  1
1995 Johnston JA, Johnson ES, Waller PR, Varshavsky A. Methotrexate inhibits proteolysis of dihydrofolate reductase by the N-end rule pathway. The Journal of Biological Chemistry. 270: 8172-8. PMID 7713922 DOI: 10.1074/jbc.270.14.8172  1
1995 Dohmen RJ, Stappen R, McGrath JP, Forrová H, Kolarov J, Goffeau A, Varshavsky A. An essential yeast gene encoding a homolog of ubiquitin-activating enzyme. The Journal of Biological Chemistry. 270: 18099-109. PMID 7629121 DOI: 10.1074/jbc.270.30.18099  1
1995 Johnson ES, Ma PC, Ota IM, Varshavsky A. A proteolytic pathway that recognizes ubiquitin as a degradation signal. The Journal of Biological Chemistry. 270: 17442-56. PMID 7615550 DOI: 10.1074/jbc.270.29.17442  1
1994 Dohmen RJ, Wu P, Varshavsky A. Heat-inducible degron: a method for constructing temperature-sensitive mutants. Science (New York, N.Y.). 263: 1273-6. PMID 8122109  1
1994 Sharp JD, Pickard RT, Chiou XG, Manetta JV, Kovacevic S, Miller JR, Varshavsky AD, Roberts EF, Strifler BA, Brems DN. Serine 228 is essential for catalytic activities of 85-kDa cytosolic phospholipase A2. The Journal of Biological Chemistry. 269: 23250-4. PMID 8083230  0.36
1994 Madura K, Varshavsky A. Degradation of G alpha by the N-end rule pathway. Science (New York, N.Y.). 265: 1454-8. PMID 8073290  1
1994 Johnsson N, Varshavsky A. Ubiquitin-assisted dissection of protein transport across membranes. The Embo Journal. 13: 2686-98. PMID 8013467  1
1994 Johnsson N, Varshavsky A. Split ubiquitin as a sensor of protein interactions in vivo. Proceedings of the National Academy of Sciences of the United States of America. 91: 10340-4. PMID 7937952 DOI: 10.1073/pnas.91.22.10340  1
1993 Madura K, Dohmen RJ, Varshavsky A. N-recognin/Ubc2 interactions in the N-end rule pathway. The Journal of Biological Chemistry. 268: 12046-54. PMID 8505328  1
1993 Shrader TE, Tobias JW, Varshavsky A. The N-end rule in Escherichia coli: cloning and analysis of the leucyl, phenylalanyl-tRNA-protein transferase gene aat. Journal of Bacteriology. 175: 4364-74. PMID 8331068  1
1993 Ota IM, Varshavsky A. A yeast protein similar to bacterial two-component regulators. Science (New York, N.Y.). 262: 566-9. PMID 8211183  1
1992 Ota IM, Varshavsky A. A gene encoding a putative tyrosine phosphatase suppresses lethality of an N-end rule-dependent mutant. Proceedings of the National Academy of Sciences of the United States of America. 89: 2355-9. PMID 1549598  1
1992 Baker RT, Tobias JW, Varshavsky A. Ubiquitin-specific proteases of Saccharomyces cerevisiae. Cloning of UBP2 and UBP3, and functional analysis of the UBP gene family. The Journal of Biological Chemistry. 267: 23364-75. PMID 1429680  1
1992 Varshavsky A. The N-end rule. Cell. 69: 725-35. PMID 1317266 DOI: 10.1016/0092-8674(92)90285-K  1
1992 Johnson ES, Bartel B, Seufert W, Varshavsky A. Ubiquitin as a degradation signal. The Embo Journal. 11: 497-505. PMID 1311250  1
1991 Tobias JW, Varshavsky A. Cloning and functional analysis of the ubiquitin-specific protease gene UBP1 of Saccharomyces cerevisiae. The Journal of Biological Chemistry. 266: 12021-8. PMID 2050695  1
1991 McGrath JP, Jentsch S, Varshavsky A. UBA 1: an essential yeast gene encoding ubiquitin-activating enzyme. The Embo Journal. 10: 227-36. PMID 1989885  1
1991 Tobias JW, Shrader TE, Rocap G, Varshavsky A. The N-end rule in bacteria. Science (New York, N.Y.). 254: 1374-7. PMID 1962196  1
1991 Baker RT, Varshavsky A. Inhibition of the N-end rule pathway in living cells. Proceedings of the National Academy of Sciences of the United States of America. 88: 1090-4. PMID 1899923  1
1991 Dohmen RJ, Madura K, Bartel B, Varshavsky A. The N-end rule is mediated by the UBC2(RAD6) ubiquitin-conjugating enzyme. Proceedings of the National Academy of Sciences of the United States of America. 88: 7351-5. PMID 1651502  1
1991 Hochstrasser M, Ellison MJ, Chau V, Varshavsky A. The short-lived MAT alpha 2 transcriptional regulator is ubiquitinated in vivo. Proceedings of the National Academy of Sciences of the United States of America. 88: 4606-10. PMID 1647011  1
1990 Bartel B, Wünning I, Varshavsky A. The recognition component of the N-end rule pathway. The Embo Journal. 9: 3179-89. PMID 2209542  1
1990 Johnson ES, Gonda DK, Varshavsky A. cis-trans recognition and subunit-specific degradation of short-lived proteins. Nature. 346: 287-91. PMID 2165217 DOI: 10.1038/346287a0  1
1990 Hochstrasser M, Varshavsky A. In vivo degradation of a transcriptional regulator: the yeast alpha 2 repressor. Cell. 61: 697-708. PMID 2111732  0.52
1989 McGrath JP, Varshavsky A. The yeast STE6 gene encodes a homologue of the mammalian multidrug resistance P-glycoprotein. Nature. 340: 400-4. PMID 2569166 DOI: 10.1038/340400a0  0.56
1989 Varshavsky A, Bachmair A, Finley D, Gonda DK, Wünning I. Targeting of proteins for degradation. Biotechnology (Reading, Mass.). 13: 109-43. PMID 2553172  0.92
1989 Chau V, Tobias JW, Bachmair A, Marriott D, Ecker DJ, Gonda DK, Varshavsky A. A multiubiquitin chain is confined to specific lysine in a targeted short-lived protein. Science (New York, N.Y.). 243: 1576-83. PMID 2538923  0.52
1989 Finley D, Bartel B, Varshavsky A. The tails of ubiquitin precursors are ribosomal proteins whose fusion to ubiquitin facilitates ribosome biogenesis. Nature. 338: 394-401. PMID 2538753 DOI: 10.1038/338394a0  1
1989 Bachmair A, Varshavsky A. The degradation signal in a short-lived protein. Cell. 56: 1019-32. PMID 2538246  0.44
1989 Gonda DK, Bachmair A, Wünning I, Tobias JW, Lane WS, Varshavsky A. Universality and structure of the N-end rule. The Journal of Biological Chemistry. 264: 16700-12. PMID 2506181  0.64
1988 Goebl MG, Yochem J, Jentsch S, McGrath JP, Varshavsky A, Byers B. The yeast cell cycle gene CDC34 encodes a ubiquitin-conjugating enzyme. Science (New York, N.Y.). 241: 1331-5. PMID 2842867  1
1988 Bartel B, Varshavsky A. Hypersensitivity to heavy water: a new conditional phenotype. Cell. 52: 935-41. PMID 2832067  1
1988 Solomon MJ, Larsen PL, Varshavsky A. Mapping protein-DNA interactions in vivo with formaldehyde: evidence that histone H4 is retained on a highly transcribed gene. Cell. 53: 937-47. PMID 2454748 DOI: 10.1016/S0092-8674(88)90469-2  1
1987 Varshavsky A, Bachmair A, Finley D. The N-end rule of selective protein turnover: mechanistic aspects and functional implications. Biochemical Society Transactions. 15: 815-6. PMID 3691950  0.92
1987 Peck LJ, Millstein L, Eversole-Cire P, Gottesfeld JM, Varshavsky A. Transcriptionally inactive oocyte-type 5S RNA genes of Xenopus laevis are complexed with TFIIIA in vitro. Molecular and Cellular Biology. 7: 3503-10. PMID 3683391  1
1987 Jentsch S, McGrath JP, Varshavsky A. The yeast DNA repair gene RAD6 encodes a ubiquitin-conjugating enzyme. Nature. 329: 131-4. PMID 3306404 DOI: 10.1038/329131a0  1
1987 Ozkaynak E, Finley D, Solomon MJ, Varshavsky A. The yeast ubiquitin genes: a family of natural gene fusions. The Embo Journal. 6: 1429-39. PMID 3038523  1
1987 Finley D, Ozkaynak E, Varshavsky A. The yeast polyubiquitin gene is essential for resistance to high temperatures, starvation, and other stresses. Cell. 48: 1035-46. PMID 3030556  0.92
1987 Solomon MJ, Varshavsky A. A nuclease-hypersensitive region forms de novo after chromosome replication. Molecular and Cellular Biology. 7: 3822-5. PMID 2824998  1
1986 Snapka RM, Kwok K, Bernard JA, Harling OK, Varshavsky A. Post-separation detection of nucleic acids and proteins by neutron activation. Proceedings of the National Academy of Sciences of the United States of America. 83: 8939-42. PMID 3466168  1
1986 Solomon MJ, Strauss F, Varshavsky A. A mammalian high mobility group protein recognizes any stretch of six A.T base pairs in duplex DNA. Proceedings of the National Academy of Sciences of the United States of America. 83: 1276-80. PMID 3456586  1
1986 Bachmair A, Finley D, Varshavsky A. In vivo half-life of a protein is a function of its amino-terminal residue. Science (New York, N.Y.). 234: 179-86. PMID 3018930  0.92
1986 Swerdlow PS, Finley D, Varshavsky A. Enhancement of immunoblot sensitivity by heating of hydrated filters. Analytical Biochemistry. 156: 147-53. PMID 3017146  0.92
1985 Ciccarelli RB, Solomon MJ, Varshavsky A, Lippard SJ. In vivo effects of cis- and trans-diamminedichloroplatinum(II) on SV40 chromosomes: differential repair, DNA-protein cross-linking, and inhibition of replication. Biochemistry. 24: 7533-40. PMID 3004558  1
1985 Solomon MJ, Varshavsky A. Formaldehyde-mediated DNA-protein crosslinking: a probe for in vivo chromatin structures. Proceedings of the National Academy of Sciences of the United States of America. 82: 6470-4. PMID 2995966  1
1985 Ciechanover A, Finley D, Varshavsky A. Mammalian cell cycle mutant defective in intracellular protein degradation and ubiquitin-protein conjugation. Progress in Clinical and Biological Research. 180: 17-31. PMID 2994083  0.92
1984 Strauss F, Varshavsky A. A protein binds to a satellite DNA repeat at three specific sites that would be brought into mutual proximity by DNA folding in the nucleosome. Cell. 37: 889-901. PMID 6540146  0.4
1984 Ciechanover A, Finley D, Varshavsky A. The ubiquitin-mediated proteolytic pathway and mechanisms of energy-dependent intracellular protein degradation. Journal of Cellular Biochemistry. 24: 27-53. PMID 6327743 DOI: 10.1002/jcb.240240104  0.92
1984 Ciechanover A, Finley D, Varshavsky A. Ubiquitin dependence of selective protein degradation demonstrated in the mammalian cell cycle mutant ts85. Cell. 37: 57-66. PMID 6327060  0.92
1984 Finley D, Ciechanover A, Varshavsky A. Thermolability of ubiquitin-activating enzyme from the mammalian cell cycle mutant ts85. Cell. 37: 43-55. PMID 6327059  0.92
1984 Ozkaynak E, Finley D, Varshavsky A. The yeast ubiquitin gene: head-to-tail repeats encoding a polyubiquitin precursor protein. Nature. 312: 663-6. PMID 6095120  0.92
1983 Wu KC, Strauss F, Varshavsky A. Nucleosome arrangement in green monkey alpha-satellite chromatin. Superimposition of non-random and apparently random patterns. Journal of Molecular Biology. 170: 93-117. PMID 6313939  0.4
1983 Varshavsky A, Levinger L, Sundin O, Barsoum J, Ozkaynak E, Swerdlow P, Finley D. Cellular and SV40 chromatin: replication, segregation, ubiquitination, nuclease-hypersensitive sites, HMG-containing nucleosomes, and heterochromatin-specific protein. Cold Spring Harbor Symposia On Quantitative Biology. 47: 511-28. PMID 6305564  0.92
1983 Swerdlow PS, Varshavsky A. Affinity of HMG17 for a mononucleosome is not influenced by the presence of ubiquitin-H2A semihistone but strongly depends on DNA fragment size. Nucleic Acids Research. 11: 387-401. PMID 6298725  0.48
1978 Varshavsky AJ, Sundin OH, Bohn MJ. SV40 viral minichromosome: preferential exposure of the origin of replication as probed by restriction endonucleases. Nucleic Acids Research. 5: 3469-77. PMID 214758 DOI: 10.1093/nar/5.10.3469  1
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