Alvaro G. Estevez - Publications

Affiliations: 
Weill Cornell Medical College, New York, NY, United States 
Area:
Neuroscience Biology

34 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Strayer AL, Dennys-Rivers CN, Ricart KC, Bae N, Beckman JS, Franco MC, Estevez AG. Ligand-independent activation of the P2X7 receptor by Hsp90 inhibition stimulates motor neuron apoptosis. Experimental Biology and Medicine (Maywood, N.J.). 1535370219853798. PMID 31142143 DOI: 10.1177/1535370219853798  0.493
2017 Ramdial K, Franco MC, Estevez AG. Cellular Mechanisms of Peroxynitrite-Induced Neuronal Death. Brain Research Bulletin. PMID 28655600 DOI: 10.1016/J.Brainresbull.2017.05.008  0.404
2016 Pasetto L, Pozzi S, Castelnovo M, Basso M, Estevez AG, Fumagalli S, De Simoni MG, Castellaneta V, Bigini P, Restelli E, Chiesa R, Trojsi F, Rosaria Monsurrò M, Callea L, Malešević M, et al. Targeting extracellular cyclophilin A reduces neuroinflammation and extends survival in a mouse model of amyotrophic lateral sclerosis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28011744 DOI: 10.1523/Jneurosci.2462-16.2016  0.409
2016 Williams JR, Trias E, Beilby PR, Lopez NI, Labut EM, Samuel Bradford C, Roberts BR, McAllum EJ, Crouch PJ, Rhoads TW, Pereira C, Son M, Elliott JL, Franco MC, Estévez AG, et al. Copper delivery to the CNS by CuATSM effectively treats motor neuron disease in SOD(G93A) mice co-expressing the copper-chaperone-for-SOD. Neurobiology of Disease. PMID 26826269 DOI: 10.1016/J.Nbd.2016.01.020  0.345
2015 Dennys CN, Armstrong J, Levy M, Byun YJ, Ramdial KR, Bott M, Rossi FH, Fernández-Valle C, Franco MC, Estevez AG. Chronic inhibitory effect of riluzole on trophic factor production. Experimental Neurology. 271: 301-307. PMID 26071088 DOI: 10.1016/J.Expneurol.2015.05.016  0.441
2014 Franco MC, Estévez AG. Tyrosine nitration as mediator of cell death. Cellular and Molecular Life Sciences : Cmls. 71: 3939-50. PMID 24947321 DOI: 10.1007/S00018-014-1662-8  0.302
2013 Franco MC, Ye Y, Refakis CA, Feldman JL, Stokes AL, Basso M, Melero Fernández de Mera RM, Sparrow NA, Calingasan NY, Kiaei M, Rhoads TW, Ma TC, Grumet M, Barnes S, Beal MF, et al. Nitration of Hsp90 induces cell death. Proceedings of the National Academy of Sciences of the United States of America. 110: E1102-11. PMID 23487751 DOI: 10.1073/Pnas.1215177110  0.461
2013 Viera L, Radmilovich M, Vargas MR, Dennys CN, Wilson L, Barnes S, Franco MC, Beckman JS, Estévez AG. Temporal patterns of tyrosine nitration in embryo heart development. Free Radical Biology & Medicine. 55: 101-8. PMID 23195686 DOI: 10.1016/J.Freeradbiomed.2012.10.535  0.315
2012 Drechsel DA, Estévez AG, Barbeito L, Beckman JS. Nitric oxide-mediated oxidative damage and the progressive demise of motor neurons in ALS. Neurotoxicity Research. 22: 251-64. PMID 22488161 DOI: 10.1007/S12640-012-9322-Y  0.491
2012 Magrané J, Sahawneh MA, Przedborski S, Estévez ÁG, Manfredi G. Mitochondrial dynamics and bioenergetic dysfunction is associated with synaptic alterations in mutant SOD1 motor neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 229-42. PMID 22219285 DOI: 10.1523/Jneurosci.1233-11.2012  0.526
2012 Gitto SB, Estévez AG, Franco MC. Nitrated Hsp90 Regulates Mitochondrial Membrane Potential and Oxygen Consumption in Cancer Cells Free Radical Biology and Medicine. 53. DOI: 10.1016/J.Freeradbiomed.2012.10.110  0.309
2011 Shi Q, Xu H, Yu H, Zhang N, Ye Y, Estevez AG, Deng H, Gibson GE. Inactivation and reactivation of the mitochondrial α-ketoglutarate dehydrogenase complex. The Journal of Biological Chemistry. 286: 17640-8. PMID 21454586 DOI: 10.1074/Jbc.M110.203018  0.302
2011 Franco MC, Refakis CA, Mehl R, Estevez AG. Nitrated Hsp90 Induces Apoptosis in Motor Neurons by a Fas-Dependent Mechanism Free Radical Biology and Medicine. 51: S28. DOI: 10.1016/J.Freeradbiomed.2011.10.066  0.518
2011 Franco MC, Ricart K, Gitto S, Janes M, Wilson L, Barnes S, Landar A, Estevez AG. Nitrated Hsp90 Decreases Mitochondrial Membrane Potential and Oxygen Consumption Free Radical Biology and Medicine. 51: S28. DOI: 10.1016/J.Freeradbiomed.2011.10.065  0.303
2009 Basso M, Samengo G, Nardo G, Massignan T, D'Alessandro G, Tartari S, Cantoni L, Marino M, Cheroni C, De Biasi S, Giordana MT, Strong MJ, Estevez AG, Salmona M, Bendotti C, et al. Characterization of detergent-insoluble proteins in ALS indicates a causal link between nitrative stress and aggregation in pathogenesis. Plos One. 4: e8130. PMID 19956584 DOI: 10.1371/Journal.Pone.0008130  0.381
2009 Bishop A, Gooch R, Eguchi A, Jeffrey S, Smallwood L, Anderson J, Estevez AG. Mitigation of peroxynitrite-mediated nitric oxide (NO) toxicity as a mechanism of induced adaptive NO resistance in the CNS. Journal of Neurochemistry. 109: 74-84. PMID 19183270 DOI: 10.1111/j.1471-4159.2009.05884.x  0.404
2007 Lu L, Zheng L, Viera L, Suswam E, Li Y, Li X, Estévez AG, King PH. Mutant Cu/Zn-superoxide dismutase associated with amyotrophic lateral sclerosis destabilizes vascular endothelial growth factor mRNA and downregulates its expression. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 7929-38. PMID 17652584 DOI: 10.1523/Jneurosci.1877-07.2007  0.355
2004 Vargas MR, Pehar M, Cassina P, Estévez AG, Beckman JS, Barbeito L. Stimulation of nerve growth factor expression in astrocytes by peroxynitrite. In Vivo (Athens, Greece). 18: 269-74. PMID 15341182  0.335
2004 Peluffo H, Shacka JJ, Ricart K, Bisig CG, Martìnez-Palma L, Pritsch O, Kamaid A, Eiserich JP, Crow JP, Barbeito L, Estèvez AG. Induction of motor neuron apoptosis by free 3-nitro-L-tyrosine. Journal of Neurochemistry. 89: 602-12. PMID 15086517 DOI: 10.1046/J.1471-4159.2004.02363.X  0.58
2004 Pehar M, Cassina P, Vargas MR, Castellanos R, Viera L, Beckman JS, Estévez AG, Barbeito L. Astrocytic production of nerve growth factor in motor neuron apoptosis: implications for amyotrophic lateral sclerosis. Journal of Neurochemistry. 89: 464-73. PMID 15056289 DOI: 10.1111/J.1471-4159.2004.02357.X  0.562
2003 Trushina E, Heldebrant MP, Perez-Terzic CM, Bortolon R, Kovtun IV, Badger JD, Terzic A, Estévez A, Windebank AJ, Dyer RB, Yao J, McMurray CT. Microtubule destabilization and nuclear entry are sequential steps leading to toxicity in Huntington's disease. Proceedings of the National Academy of Sciences of the United States of America. 100: 12171-6. PMID 14527999 DOI: 10.1073/Pnas.2034961100  0.326
2002 Raoul C, Estévez AG, Nishimune H, Cleveland DW, deLapeyrière O, Henderson CE, Haase G, Pettmann B. Motoneuron death triggered by a specific pathway downstream of Fas. potentiation by ALS-linked SOD1 mutations. Neuron. 35: 1067-83. PMID 12354397 DOI: 10.1016/S0896-6273(02)00905-4  0.452
2002 Estévez AG, Jordán J. Nitric oxide and superoxide, a deadly cocktail. Annals of the New York Academy of Sciences. 962: 207-11. PMID 12076976 DOI: 10.1111/J.1749-6632.2002.Tb04069.X  0.477
2002 Cassina P, Peluffo H, Pehar M, Martinez-Palma L, Ressia A, Beckman JS, Estévez AG, Barbeito L. Peroxynitrite triggers a phenotypic transformation in spinal cord astrocytes that induces motor neuron apoptosis. Journal of Neuroscience Research. 67: 21-9. PMID 11754077 DOI: 10.1002/Jnr.10107  0.567
2001 Beckman JS, Estévez AG, Crow JP, Barbeito L. Superoxide dismutase and the death of motoneurons in ALS. Trends in Neurosciences. 24: S15-20. PMID 11881740 DOI: 10.1016/S0166-2236(00)01981-0  0.345
2000 Lang JD, Chumley P, Eiserich JP, Estevez A, Bamberg T, Adhami A, Crow J, Freeman BA. Hypercapnia induces injury to alveolar epithelial cells via a nitric oxide-dependent pathway. American Journal of Physiology. Lung Cellular and Molecular Physiology. 279: L994-1002. PMID 11053037 DOI: 10.1152/Ajplung.2000.279.5.L994  0.305
2000 Estévez AG, Sampson JB, Zhuang YX, Spear N, Richardson GJ, Crow JP, Tarpey MM, Barbeito L, Beckman JS. Liposome-delivered superoxide dismutase prevents nitric oxide-dependent motor neuron death induced by trophic factor withdrawal. Free Radical Biology & Medicine. 28: 437-46. PMID 10699756 DOI: 10.1016/S0891-5849(99)00261-0  0.586
1999 Estévez AG, Crow JP, Sampson JB, Reiter C, Zhuang Y, Richardson GJ, Tarpey MM, Barbeito L, Beckman JS. Induction of nitric oxide-dependent apoptosis in motor neurons by zinc-deficient superoxide dismutase. Science (New York, N.Y.). 286: 2498-500. PMID 10617463 DOI: 10.1126/Science.286.5449.2498  0.551
1999 Eiserich JP, Estevez AG, Bamberg TV, Yao Zu Ye, Chumley PH, Beckman JS, Freeman BA. Microtubule dysfunction by posttranslational nitrotyrosination of α- tubulin: A nitric oxide-dependent mechanism of cellular injury Proceedings of the National Academy of Sciences of the United States of America. 96: 6365-6370. PMID 10339593 DOI: 10.1073/Pnas.96.11.6365  0.347
1998 Estévez AG, Spear N, Manuel SM, Radi R, Henderson CE, Barbeito L, Beckman JS. Nitric oxide and superoxide contribute to motor neuron apoptosis induced by trophic factor deprivation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 923-31. PMID 9437014 DOI: 10.1523/Jneurosci.18-03-00923.1998  0.558
1998 Estévez AG, Spear N, Thompson JA, Cornwell TL, Radi R, Barbeito L, Beckman JS. Nitric Oxide-Dependent Production of cGMP Supports the Survival of Rat Embryonic Motor Neurons Cultured with Brain-Derived Neurotrophic Factor The Journal of Neuroscience. 18: 3708-3714. DOI: 10.1523/Jneurosci.18-10-03708.1998  0.534
1997 Peluffo H, Estevez A, Barbeito L, Stutzmann JM. Riluzole promotes survival of rat motoneurons in vitro by stimulating trophic activity produced by spinal astrocyte monolayers. Neuroscience Letters. 228: 207-11. PMID 9218644 DOI: 10.1016/S0304-3940(97)00384-4  0.306
1995 Estévez AG, Radi R, Barbeito L, Shin JT, Thompson JA, Beckman JS. Peroxynitrite-induced cytotoxicity in PC12 cells: evidence for an apoptotic mechanism differentially modulated by neurotrophic factors. Journal of Neurochemistry. 65: 1543-50. PMID 7561848 DOI: 10.1046/J.1471-4159.1995.65041543.X  0.323
1995 Estevez AG, Stutzmann JM, Barbeito L. Protective effect of riluzole on excitatory amino acid-mediated neurotoxicity in motoneuron-enriched cultures. European Journal of Pharmacology. 280: 47-53. PMID 7498253 DOI: 10.1016/0014-2999(95)00186-O  0.323
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