Year |
Citation |
Score |
2023 |
Ullah I, Escudie F, Scandale I, Gilani Z, Gendron-Lepage G, Gaudette F, Mowbray C, Fraisse L, Bazin R, Finzi A, Mothes W, Kumar P, Chatelain E, Uchil PD. Combinatorial Regimens Augment Drug Monotherapy for SARS-CoV-2 Clearance in Mice. Biorxiv : the Preprint Server For Biology. PMID 37398307 DOI: 10.1101/2023.05.31.543159 |
0.314 |
|
2022 |
Prévost J, Anand SP, Rajashekar JK, Zhu L, Richard J, Goyette G, Medjahed H, Gendron-Lepage G, Chen HC, Chen Y, Horwitz JA, Grunst MW, Zolla-Pazner S, Haynes BF, Burton DR, ... ... Kumar P, et al. HIV-1 Vpu restricts Fc-mediated effector functions in vivo. Cell Reports. 41: 111624. PMID 36351384 DOI: 10.1016/j.celrep.2022.111624 |
0.353 |
|
2020 |
Zhao Y, Amodio M, Vander Wyk B, Gerritsen B, Kumar MM, van Dijk D, Moon K, Wang X, Malawista A, Richards MM, Cahill ME, Desai A, Sivadasan J, Venkataswamy MM, Ravi V, ... ... Kumar P, et al. Single cell immune profiling of dengue virus patients reveals intact immune responses to Zika virus with enrichment of innate immune signatures. Plos Neglected Tropical Diseases. 14: e0008112. PMID 32150565 DOI: 10.1371/Journal.Pntd.0008112 |
0.463 |
|
2019 |
Ventura JD, Beloor J, Allen E, Zhang T, Haugh KA, Uchil PD, Ochsenbauer C, Kieffer C, Kumar P, Hope TJ, Mothes W. Longitudinal bioluminescent imaging of HIV-1 infection during antiretroviral therapy and treatment interruption in humanized mice. Plos Pathogens. 15: e1008161. PMID 31805155 DOI: 10.1371/Journal.Ppat.1008161 |
0.423 |
|
2019 |
Ullah I, Chung K, Beloor J, Lee SK, Kumar P. A Positioning Device for the Placement of Mice During Intranasal siRNA Delivery to the Central Nervous System. Journal of Visualized Experiments : Jove. PMID 31475960 DOI: 10.3791/59201 |
0.344 |
|
2019 |
Kumar P, Nagarajan A, Uchil PD. Introducing Genes into Cultured Mammalian Cells. Cold Spring Harbor Protocols. PMID 31285274 DOI: 10.1101/Pdb.Top095406 |
0.355 |
|
2019 |
Allen TM, Brehm MA, Bridges S, Ferguson S, Kumar P, Mirochnitchenko O, Palucka K, Pelanda R, Sanders-Beer B, Shultz LD, Su L, PrabhuDas M. Humanized immune system mouse models: progress, challenges and opportunities. Nature Immunology. PMID 31160798 DOI: 10.1038/S41590-019-0416-Z |
0.329 |
|
2019 |
Kudalkar SN, Ullah I, Bertoletti N, Mandl HK, Cisneros JA, Beloor J, Chan AH, Quijano E, Saltzman WM, Jorgensen WL, Kumar P, Anderson KS. Structural and pharmacological evaluation of a novel non-nucleoside reverse transcriptase inhibitor as a promising long acting nanoformulation for treating HIV. Antiviral Research. PMID 31034849 DOI: 10.1016/J.Antiviral.2019.04.010 |
0.38 |
|
2019 |
Kumar P, Nagarajan A, Uchil PD. DNA Transfection Mediated by Cationic Lipid Reagents. Cold Spring Harbor Protocols. 2019: pdb.prot095414. PMID 30824617 DOI: 10.1101/Pdb.Prot095414 |
0.316 |
|
2018 |
Kudalkar SN, Beloor J, Quijano E, Spasov KA, Lee WG, Cisneros JA, Saltzman WM, Kumar P, Jorgensen WL, Anderson KS. Reply to Pandey et al.: Understanding the efficacy of a potential antiretroviral drug candidate in humanized mouse model of HIV infection. Proceedings of the National Academy of Sciences of the United States of America. PMID 30097540 DOI: 10.1073/Pnas.1810136115 |
0.314 |
|
2018 |
Beloor J, Maes N, Ullah I, Uchil P, Jackson A, Fikrig E, Lee SK, Kumar P. Small Interfering RNA-Mediated Control of Virus Replication in the CNS Is Therapeutic and Enables Natural Immunity to West Nile Virus. Cell Host & Microbe. PMID 29606496 DOI: 10.1016/J.Chom.2018.03.001 |
0.556 |
|
2017 |
Kudalkar SN, Beloor J, Quijano E, Spasov KA, Lee WG, Cisneros JA, Saltzman WM, Kumar P, Jorgensen WL, Anderson KS. From in silico hit to long-acting late-stage preclinical candidate to combat HIV-1 infection. Proceedings of the National Academy of Sciences of the United States of America. PMID 29279368 DOI: 10.1073/Pnas.1717932115 |
0.347 |
|
2017 |
Kudalkar SN, Beloor J, Chan AH, Lee WG, Jorgensen WL, Kumar P, Anderson KS. Structural and Preclinical Studies of Computationally-Designed Non-nucleoside Reverse Transcriptase Inhibitors for Treating HIV infection. Molecular Pharmacology. PMID 28167742 DOI: 10.1124/Mol.116.107755 |
0.305 |
|
2016 |
Ullah I, Chung K, Beloor J, Kim J, Cho M, Kim N, Lee KY, Kumar P, Lee SK. Trileucine residues in a ligand-CPP-based siRNA delivery platform improve endosomal escape of siRNA. Journal of Drug Targeting. 1-29. PMID 27820977 DOI: 10.1080/1061186X.2016.1258566 |
0.358 |
|
2016 |
Bahal R, Ali McNeer N, Quijano E, Liu Y, Sulkowski P, Turchick A, Lu YC, Bhunia DC, Manna A, Greiner DL, Brehm MA, Cheng CJ, López-Giráldez F, Ricciardi A, Beloor J, ... ... Kumar P, et al. In vivo correction of anaemia in β-thalassemic mice by γPNA-mediated gene editing with nanoparticle delivery. Nature Communications. 7: 13304. PMID 27782131 DOI: 10.1038/Ncomms13304 |
0.325 |
|
2015 |
Akkina RK, Allam A, Balazs AB, Blankson J, Burnett JC, Casares S, Garcia JV, Hasenkrug K, Kashanchi F, Kitchen S, Klein F, Kumar P, Luster AD, Poluektova LY, Rao M, et al. Improvements and Limitations of Humanized Mouse Models for HIV Research: NIH/NIAID "Meet the Experts" 2015 Workshop Summary. Aids Research and Human Retroviruses. PMID 26670361 DOI: 10.1089/Aid.2015.0258 |
0.347 |
|
2015 |
Sewald X, Ladinsky MS, Uchil PD, Beloor J, Pi R, Herrmann C, Motamedi N, Murooka TT, Brehm MA, Greiner DL, Shultz LD, Mempel TR, Bjorkman PJ, Kumar P, Mothes W. Retroviruses use CD169-mediated trans-infection of permissive lymphocytes to establish infection. Science (New York, N.Y.). PMID 26429886 DOI: 10.1126/Science.Aab2749 |
0.414 |
|
2015 |
Beloor J, Zeller S, Choi CS, Lee SK, Kumar P. Cationic cell-penetrating peptides as vehicles for siRNA delivery. Therapeutic Delivery. 6: 491-507. PMID 25996046 DOI: 10.4155/Tde.15.2 |
0.36 |
|
2015 |
Liu S, Jackson A, Beloor J, Kumar P, Sutton R. Adenovirus-vectored broadly neutralizing antibodies directed against gp120 prevent HIV-1 acquisition in humanized mice. Human Gene Therapy. PMID 25953321 DOI: 10.1089/Hum.2014.146 |
0.378 |
|
2015 |
Deng K, Pertea M, Rongvaux A, Wang L, Durand CM, Ghiaur G, Lai J, McHugh HL, Hao H, Zhang H, Margolick JB, Gurer C, Murphy AJ, Valenzuela DM, Yancopoulos GD, ... ... Kumar P, et al. Broad CTL response is required to clear latent HIV-1 due to dominance of escape mutations. Nature. 517: 381-5. PMID 25561180 DOI: 10.1038/Nature14053 |
0.428 |
|
2015 |
Beloor J, Ramakrishna S, Nam K, Seon Choi C, Kim J, Kim SH, Cho HJ, Shin H, Kim H, Kim SW, Lee SK, Kumar P. Effective gene delivery into human stem cells with a cell-targeting Peptide-modified bioreducible polymer. Small (Weinheim An Der Bergstrasse, Germany). 11: 2069-79. PMID 25515928 DOI: 10.1002/Smll.201402933 |
0.335 |
|
2014 |
Beloor J, Nam HY, Lee SK, Kumar P. Arginine-grafted biodegradable polymer: a versatile transfection reagent for both DNA and siRNA. Methods in Molecular Biology (Clifton, N.J.). 1176: 115-26. PMID 25030923 DOI: 10.1007/978-1-4939-0992-6_10 |
0.307 |
|
2013 |
Schleifman EB, McNeer NA, Jackson A, Yamtich J, Brehm MA, Shultz LD, Greiner DL, Kumar P, Saltzman WM, Glazer PM. Site-specific Genome Editing in PBMCs With PLGA Nanoparticle-delivered PNAs Confers HIV-1 Resistance in Humanized Mice. Molecular Therapy. Nucleic Acids. 2: e135. PMID 24253260 DOI: 10.1038/Mtna.2013.59 |
0.393 |
|
2013 |
McNeer NA, Schleifman EB, Cuthbert A, Brehm M, Jackson A, Cheng C, Anandalingam K, Kumar P, Shultz LD, Greiner DL, Mark Saltzman W, Glazer PM. Systemic delivery of triplex-forming PNA and donor DNA by nanoparticles mediates site-specific genome editing of human hematopoietic cells in vivo. Gene Therapy. 20: 658-69. PMID 23076379 DOI: 10.1038/Gt.2012.82 |
0.339 |
|
2012 |
Lee SK, Siefert A, Beloor J, Fahmy TM, Kumar P. Cell-specific siRNA delivery by peptides and antibodies. Methods in Enzymology. 502: 91-122. PMID 22208983 DOI: 10.1016/B978-0-12-416039-2.00005-7 |
0.343 |
|
2012 |
Beloor J, Choi CS, Nam HY, Park M, Kim SH, Jackson A, Lee KY, Kim SW, Kumar P, Lee SK. Arginine-engrafted biodegradable polymer for the systemic delivery of therapeutic siRNA. Biomaterials. 33: 1640-50. PMID 22112761 DOI: 10.1016/J.Biomaterials.2011.11.008 |
0.343 |
|
2011 |
Choi S, Lee J, Kumar P, Lee KY, Lee SK. Single chain variable fragment CD7 antibody conjugated PLGA/HDAC inhibitor immuno-nanoparticles: developing human T cell-specific nano-technology for delivery of therapeutic drugs targeting latent HIV. Journal of Controlled Release : Official Journal of the Controlled Release Society. 152: e9-10. PMID 22195949 DOI: 10.1016/J.Jconrel.2011.08.089 |
0.32 |
|
2011 |
Schleifman EB, Bindra R, Leif J, del Campo J, Rogers FA, Uchil P, Kutsch O, Shultz LD, Kumar P, Greiner DL, Glazer PM. Targeted disruption of the CCR5 gene in human hematopoietic stem cells stimulated by peptide nucleic acids. Chemistry & Biology. 18: 1189-98. PMID 21944757 DOI: 10.1016/J.Chembiol.2011.07.010 |
0.398 |
|
2010 |
Kim SS, Ye C, Kumar P, Chiu I, Subramanya S, Wu H, Shankar P, Manjunath N. Targeted delivery of siRNA to macrophages for anti-inflammatory treatment. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 993-1001. PMID 20216529 DOI: 10.1038/Mt.2010.27 |
0.309 |
|
2010 |
Subramanya S, Kim SS, Abraham S, Yao J, Kumar M, Kumar P, Haridas V, Lee SK, Shultz LD, Greiner D, N M, Shankar P. Targeted delivery of small interfering RNA to human dendritic cells to suppress dengue virus infection and associated proinflammatory cytokine production. Journal of Virology. 84: 2490-501. PMID 20015996 DOI: 10.1128/Jvi.02105-08 |
0.448 |
|
2010 |
Kim SS, Peer D, Kumar P, Subramanya S, Wu H, Asthana D, Habiro K, Yang YG, Manjunath N, Shimaoka M, Shankar P. RNAi-mediated CCR5 silencing by LFA-1-targeted nanoparticles prevents HIV infection in BLT mice. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 370-6. PMID 19997090 DOI: 10.1038/Mt.2009.271 |
0.466 |
|
2009 |
Lee SK, Kumar P. Conditional RNAi: towards a silent gene therapy. Advanced Drug Delivery Reviews. 61: 650-64. PMID 19394374 DOI: 10.1016/J.Addr.2009.03.016 |
0.32 |
|
2009 |
Kim S, Peer D, Kumar P, Shimaoka M, Shankar P. T.86. siRNA Delivery with Integrin LFA-1-targeted Nanoparticles Prevents HIV Infection in Humanized Mice Clinical Immunology. 131. DOI: 10.1016/J.Clim.2009.03.221 |
0.368 |
|
2008 |
Kumar P, Ban HS, Kim SS, Wu H, Pearson T, Greiner DL, Laouar A, Yao J, Haridas V, Habiro K, Yang YG, Jeong JH, Lee KY, Kim YH, Kim SW, et al. T cell-specific siRNA delivery suppresses HIV-1 infection in humanized mice. Cell. 134: 577-86. PMID 18691745 DOI: 10.1016/J.Cell.2008.06.034 |
0.431 |
|
2008 |
Son J, Uchil PD, Kim YB, Shankar P, Kumar P, Lee SK. Effective suppression of HIV-1 by artificial bispecific miRNA targeting conserved sequences with tolerance for wobble base-pairing. Biochemical and Biophysical Research Communications. 374: 214-8. PMID 18619945 DOI: 10.1016/J.Bbrc.2008.06.125 |
0.332 |
|
2007 |
Kumar P, Wu H, McBride JL, Jung KE, Kim MH, Davidson BL, Lee SK, Shankar P, Manjunath N. Transvascular delivery of small interfering RNA to the central nervous system. Nature. 448: 39-43. PMID 17572664 DOI: 10.1038/Nature05901 |
0.379 |
|
2006 |
Manjunath N, Kumar P, Lee SK, Shankar P. Interfering antiviral immunity: application, subversion, hope? Trends in Immunology. 27: 328-35. PMID 16753342 DOI: 10.1016/J.It.2006.05.006 |
0.439 |
|
2006 |
Kumar P, Lee SK, Shankar P, Manjunath N. A single siRNA suppresses fatal encephalitis induced by two different flaviviruses. Plos Medicine. 3: e96. PMID 16464133 DOI: 10.1371/Journal.Pmed.0030096 |
0.418 |
|
2005 |
Lee SK, Dykxhoorn DM, Kumar P, Ranjbar S, Song E, Maliszewski LE, François-Bongarçon V, Goldfeld A, Swamy NM, Lieberman J, Shankar P. Lentiviral delivery of short hairpin RNAs protects CD4 T cells from multiple clades and primary isolates of HIV. Blood. 106: 818-26. PMID 15831707 DOI: 10.1182/Blood-2004-10-3959 |
0.324 |
|
2004 |
Kumar P, Krishna VD, Sulochana P, Nirmala G, Haridattatreya M, Satchidanandam V. Cell-mediated immune responses in healthy children with a history of subclinical infection with Japanese encephalitis virus: analysis of CD4+ and CD8+ T cell target specificities by intracellular delivery of viral proteins using the human immunodeficiency virus Tat protein transduction domain. The Journal of General Virology. 85: 471-82. PMID 14769905 DOI: 10.1099/vir.0.19531-0 |
0.366 |
|
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