| Year |
Citation |
Score |
| 2024 |
Mohammadkhani A, Mitchell C, James MH, Borgland SL, Dayas CV. Contribution of hypothalamic orexin (hypocretin) circuits to pathologies of motivation. British Journal of Pharmacology. PMID 39317446 DOI: 10.1111/bph.17325 |
0.692 |
|
| 2024 |
Millard SJ, Hoang IB, Sherwood S, Taira M, Reyes V, Greer Z, O'Connor SL, Wassum KM, James MH, Barker DJ, Sharpe MJ. Cognitive representations of intracranial self-stimulation of midbrain dopamine neurons depend on stimulation frequency. Nature Neuroscience. PMID 38741021 DOI: 10.1038/s41593-024-01643-1 |
0.756 |
|
| 2023 |
Zhang VY, O'Connor SL, Welsh WJ, James MH. Machine learning models to predict ligand binding affinity for the orexin 1 receptor. Artificial Intelligence Chemistry. 2. PMID 38476266 DOI: 10.1016/j.aichem.2023.100040 |
0.735 |
|
| 2023 |
Knowles LG, Armanious AJ, Peng Y, Welsh WJ, James MH. Recent advances in drug discovery efforts targeting the sigma 1 receptor system: Implications for novel medications designed to reduce excessive drug and food seeking. Addiction Neuroscience. 8. PMID 37753198 DOI: 10.1016/j.addicn.2023.100126 |
0.305 |
|
| 2022 |
James MH, Aston-Jones G. Orexin Reserve: A Mechanistic Framework for the Role of Orexins (Hypocretins) in Addiction. Biological Psychiatry. 92: 836-844. PMID 36328706 DOI: 10.1016/j.biopsych.2022.06.027 |
0.329 |
|
| 2022 |
Giannotti G, Mottarlini F, Heinsbroek JA, Mandel MR, James MH, Peters J. Oxytocin and orexin systems bidirectionally regulate the ability of opioid cues to bias reward seeking. Translational Psychiatry. 12: 432. PMID 36195606 DOI: 10.1038/s41398-022-02161-z |
0.315 |
|
| 2022 |
O'Connor SL, Aston-Jones G, James MH. Novelty preference does not predict trait cocaine behaviors in male rats. Addiction Neuroscience. 2. PMID 35425947 DOI: 10.1016/j.addicn.2022.100013 |
0.811 |
|
| 2021 |
Brown RM, Dayas C, James M, Smith RJ. NEW DIRECTIONS IN MODELLING DYSREGULATED REWARD SEEKING FOR FOOD AND DRUGS. Neuroscience and Biobehavioral Reviews. PMID 34736883 DOI: 10.1016/j.neubiorev.2021.10.043 |
0.71 |
|
| 2021 |
Mehr JB, Bilotti MM, James MH. Orexin (hypocretin) and addiction. Trends in Neurosciences. 44: 852-855. PMID 34642086 DOI: 10.1016/j.tins.2021.09.002 |
0.335 |
|
| 2021 |
Pantazis CB, James MH, O'Connor S, Shin N, Aston-Jones G. Orexin-1 receptor signaling in ventral tegmental area mediates cue-driven demand for cocaine. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 34635803 DOI: 10.1038/s41386-021-01173-5 |
0.809 |
|
| 2021 |
O'Connor SL, Aston-Jones G, James MH. The sensation-seeking trait confers a dormant susceptibility to addiction that is revealed by intermittent cocaine self-administration in rats. Neuropharmacology. 108566. PMID 33862028 DOI: 10.1016/j.neuropharm.2021.108566 |
0.808 |
|
| 2020 |
James MH, Fragale JE, O'Connor SL, Zimmer BA, Aston-Jones G. The orexin (hypocretin) neuropeptide system is a target for novel therapeutics to treat cocaine use disorder with alcohol co-abuse. Neuropharmacology. 108359. PMID 33091458 DOI: 10.1016/j.neuropharm.2020.108359 |
0.804 |
|
| 2020 |
Fragale JE, James MH, Aston-Jones G. Intermittent self-administration of fentanyl induces a multifaceted addiction state associated with persistent changes in the orexin system. Addiction Biology. e12946. PMID 32798290 DOI: 10.1111/Adb.12946 |
0.524 |
|
| 2020 |
James MH. Mimicking Human Drug Consumption Patterns in Rat Engages Corticostriatal Circuitry. Neuroscience. PMID 32682655 DOI: 10.1016/J.Neuroscience.2020.06.012 |
0.337 |
|
| 2020 |
James MH, Mahler SV. Do striatal push/pull circuits hold the key to compulsive, relapsing heroin addiction? : A Research Highlight on: Chemogenetic modulation of accumbens direct or indirect pathways bidirectionally alters reinstatement of heroin-seeking in high- but not low-risk rats, by O'Neal et al. (2019). Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 31974443 DOI: 10.1038/S41386-020-0615-1 |
0.345 |
|
| 2019 |
Mohammadkhani A, Fragale JE, Pantazis CB, Bowrey HE, James MH, Aston-Jones G. Orexin-1 receptor signaling in ventral pallidum regulates motivation for the opioid remifentanil. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 31641055 DOI: 10.1523/Jneurosci.0255-19.2019 |
0.436 |
|
| 2019 |
Bello NT, Yeh CY, James MH. Reduced Sensory-Evoked Locus Coeruleus-Norepinephrine Neural Activity in Female Rats With a History of Dietary-Induced Binge Eating. Frontiers in Psychology. 10: 1966. PMID 31551861 DOI: 10.3389/Fpsyg.2019.01966 |
0.355 |
|
| 2019 |
Mohammadkhani A, James MH, Pantazis CB, Aston-Jones G. Persistent effects of the orexin-1 receptor antagonist SB-334867 on motivation for the fast acting opioid remifentanil. Brain Research. 146461. PMID 31526801 DOI: 10.1016/J.Brainres.2019.146461 |
0.438 |
|
| 2019 |
Pantazis CB, James MH, Bentzley BS, Aston-Jones G. The number of lateral hypothalamus orexin/hypocretin neurons contributes to individual differences in cocaine demand. Addiction Biology. e12795. PMID 31297913 DOI: 10.1111/Adb.12795 |
0.563 |
|
| 2019 |
Fragale JE, Pantazis CB, James MH, Aston-Jones G. The role of orexin-1 receptor signaling in demand for the opioid fentanyl. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 31112988 DOI: 10.1038/S41386-019-0420-X |
0.423 |
|
| 2019 |
Wiskerke J, James MH, Aston-Jones G. The orexin-1 receptor antagonist SB-334867 reduces motivation, but not inhibitory control, in a rat stop signal task. Brain Research. PMID 31002819 DOI: 10.1016/J.Brainres.2019.04.017 |
0.428 |
|
| 2018 |
Yeoh JW, James MH, Adams CD, Bains JS, Sakurai T, Aston-Jones G, Graham BA, Dayas CV. Activation of lateral hypothalamic group III mGluRs suppresses cocaine-seeking following abstinence and normalizes drug-associated increases in excitatory drive to orexin/hypocretin cells. Neuropharmacology. PMID 30253175 DOI: 10.1016/J.Neuropharm.2018.09.033 |
0.791 |
|
| 2018 |
James MH, Bowrey HE, Stopper CM, Aston-Jones G. Demand elasticity predicts addiction endophenotypes and the therapeutic efficacy of an orexin/hypocretin-1 receptor antagonist in rats. The European Journal of Neuroscience. PMID 30240516 DOI: 10.1111/Ejn.14166 |
0.518 |
|
| 2018 |
James MH, Stopper CM, Zimmer BA, Koll NE, Bowrey HE, Aston-Jones G. Increased Number and Activity of a Lateral Subpopulation of Hypothalamic Orexin/Hypocretin Neurons Underlies the Expression of an Addicted State in Rats. Biological Psychiatry. PMID 30219208 DOI: 10.1016/J.Biopsych.2018.07.022 |
0.417 |
|
| 2017 |
James MH, McGlinchey EM, Vattikonda A, Mahler SV, Aston-Jones G. Cued reinstatement of cocaine- but not sucrose-seeking is dependent upon dopamine signaling in prelimbic cortex and is associated with recruitment of prelimbic neurons that project to contralateral nucleus accumbens core. The International Journal of Neuropsychopharmacology. PMID 29165565 DOI: 10.1093/Ijnp/Pyx107 |
0.494 |
|
| 2017 |
Quinn RK, James MH, Hawkins GE, Brown AL, Heathcote A, Smith DW, Cairns MJ, Dayas CV. Temporally specific miRNA expression patterns in the dorsal and ventral striatum of addiction-prone rats. Addiction Biology. PMID 28612502 DOI: 10.1111/Adb.12520 |
0.706 |
|
| 2017 |
James MH, Aston-Jones G. Orexin/Hypocretin, Central Amygdala, and Escalation of Cocaine Intake. Biological Psychiatry. 81: 552-553. PMID 28283054 DOI: 10.1016/J.Biopsych.2017.01.010 |
0.524 |
|
| 2017 |
James MH, Campbell EJ, Dayas CV. Role of the Orexin/Hypocretin System in Stress-Related Psychiatric Disorders. Current Topics in Behavioral Neurosciences. PMID 28083790 DOI: 10.1007/7854_2016_56 |
0.669 |
|
| 2016 |
James MH, Mahler SV, Moorman DE, Aston-Jones G. A Decade of Orexin/Hypocretin and Addiction: Where Are We Now? Current Topics in Behavioral Neurosciences. PMID 28012090 DOI: 10.1007/7854_2016_57 |
0.495 |
|
| 2016 |
Moorman DE, James MH, Kilroy EA, Aston-Jones G. Orexin/hypocretin-1 receptor antagonism reduces ethanol self-administration and reinstatement selectively in highly-motivated rats. Brain Research. PMID 27771284 DOI: 10.1016/J.Brainres.2016.10.018 |
0.367 |
|
| 2016 |
James MH, Aston-Jones G. The Ventral Pallidum: Proposed Integrator of Positive and Negative Factors in Cocaine Abuse. Neuron. 92: 5-8. PMID 27710789 DOI: 10.1016/J.Neuron.2016.09.042 |
0.524 |
|
| 2016 |
McGlinchey EM, James MH, Mahler SV, Pantazis C, Aston-Jones G. Prelimbic to Accumbens Core Pathway Is Recruited in a Dopamine-Dependent Manner to Drive Cued Reinstatement of Cocaine Seeking. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 8700-11. PMID 27535915 DOI: 10.1523/Jneurosci.1291-15.2016 |
0.591 |
|
| 2016 |
James MH, Quinn R, Ong LK, Levi EM, Smith DW, Dickson PW, Dayas CV. Rapamycin reduces motivated responding for cocaine and alters GluA1 expression inthe ventral but not dorsal striatum. European Journal of Pharmacology. PMID 27181066 DOI: 10.1016/J.Ejphar.2016.05.013 |
0.771 |
|
| 2016 |
Moorman DE, James MH, Kilroy EA, Aston-Jones G. Orexin/hypocretin neuron activation is correlated with alcohol seeking and preference in a topographically specific manner. The European Journal of Neuroscience. PMID 26750264 DOI: 10.1111/Ejn.13170 |
0.393 |
|
| 2014 |
Moorman DE, James MH, McGlinchey EM, Aston-Jones G. Differential roles of medial prefrontal subregions in the regulation of drug seeking. Brain Research. PMID 25529632 DOI: 10.1016/J.Brainres.2014.12.024 |
0.503 |
|
| 2014 |
Yeoh JW, James MH, Graham BA, Dayas CV. Electrophysiological characteristics of paraventricular thalamic (PVT) neurons in response to cocaine and cocaine- and amphetamine-regulated transcript (CART). Frontiers in Behavioral Neuroscience. 8: 280. PMID 25309361 DOI: 10.3389/Fnbeh.2014.00280 |
0.814 |
|
| 2014 |
Mahler SV, Moorman DE, Smith RJ, James MH, Aston-Jones G. Motivational activation: a unifying hypothesis of orexin/hypocretin function. Nature Neuroscience. 17: 1298-303. PMID 25254979 DOI: 10.1038/Nn.3810 |
0.368 |
|
| 2014 |
James MH, Campbell EJ, Walker FR, Smith DW, Richardson HN, Hodgson DM, Dayas CV. Exercise reverses the effects of early life stress on orexin cell reactivity in male but not female rats. Frontiers in Behavioral Neuroscience. 8: 244. PMID 25100956 DOI: 10.3389/Fnbeh.2014.00244 |
0.654 |
|
| 2014 |
Zouikr I, James MH, Campbell EJ, Clifton VL, Beagley KW, Dayas CV, Hodgson DM. Altered formalin-induced pain and Fos induction in the periaqueductal grey of preadolescent rats following neonatal LPS exposure. Plos One. 9: e98382. PMID 24878577 DOI: 10.1371/Journal.Pone.0098382 |
0.638 |
|
| 2014 |
Yeoh JW, Campbell EJ, James MH, Graham BA, Dayas CV. Orexin antagonists for neuropsychiatric disease: progress and potential pitfalls. Frontiers in Neuroscience. 8: 36. PMID 24616658 DOI: 10.3389/Fnins.2014.00036 |
0.728 |
|
| 2014 |
James MH, Quinn RK, Ong LK, Levi EM, Charnley JL, Smith DW, Dickson PW, Dayas CV. mTORC1 inhibition in the nucleus accumbens 'protects' against the expression of drug seeking and 'relapse' and is associated with reductions in GluA1 AMPAR and CAMKIIα levels. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 1694-702. PMID 24469593 DOI: 10.1038/Npp.2014.16 |
0.802 |
|
| 2014 |
Hodgson D, Campbell E, Zouikr I, Watters S, James M, Dayas C. 94. The involvement of orexin (hypocretin) in the formalin-induced inflammatory pain response in adulthood following a neonatal bacterial immune challenge Brain, Behavior, and Immunity. 40: e27-e28. DOI: 10.1016/J.Bbi.2014.06.114 |
0.64 |
|
| 2013 |
James MH, Dayas CV. What about me…? The PVT: a role for the paraventricular thalamus (PVT) in drug-seeking behavior. Frontiers in Behavioral Neuroscience. 7: 18. PMID 23509439 DOI: 10.3389/Fnbeh.2013.00018 |
0.708 |
|
| 2013 |
James MH, Yeoh JW, Graham BA, Dayas CV. Insights for Developing Pharmacological Treatments for Psychostimulant Relapse Targeting Hypothalamic Peptide Systems Journal of Addiction Research and Therapy. 2013: 2-13. DOI: 10.4172/2155-6105.S4-008 |
0.486 |
|
| 2012 |
Yeoh JW, James MH, Jobling P, Bains JS, Graham BA, Dayas CV. Cocaine potentiates excitatory drive in the perifornical/lateral hypothalamus. The Journal of Physiology. 590: 3677-89. PMID 22641785 DOI: 10.1113/Jphysiol.2012.230268 |
0.8 |
|
| 2011 |
James MH, Charnley JL, Flynn JR, Smith DW, Dayas CV. Propensity to 'relapse' following exposure to cocaine cues is associated with the recruitment of specific thalamic and epithalamic nuclei. Neuroscience. 199: 235-42. PMID 21985936 DOI: 10.1016/J.Neuroscience.2011.09.047 |
0.775 |
|
| 2011 |
James MH, Charnley JL, Levi EM, Jones E, Yeoh JW, Smith DW, Dayas CV. Orexin-1 receptor signalling within the ventral tegmental area, but not the paraventricular thalamus, is critical to regulating cue-induced reinstatement of cocaine-seeking. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 14: 684-90. PMID 21447232 DOI: 10.1017/S1461145711000423 |
0.808 |
|
| 2010 |
James MH, Charnley JL, Jones E, Levi EM, Yeoh JW, Flynn JR, Smith DW, Dayas CV. Cocaine- and amphetamine-regulated transcript (CART) signaling within the paraventricular thalamus modulates cocaine-seeking behaviour. Plos One. 5: e12980. PMID 20886038 DOI: 10.1371/Journal.Pone.0012980 |
0.82 |
|
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