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Morgan H. James - Publications

Affiliations: 
Anatomy The University of Newcastle 
Area:
Addiction Neurobiology , VTA, Hypothalamus
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37 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 James MH, Fragale JE, O'Connor SL, Zimmer BA, Aston-Jones G. The orexin (hypocretin) neuropeptide system is a target for novel therapeutics to treat cocaine use disorder with alcohol co-abuse. Neuropharmacology. 108359. PMID 33091458 DOI: 10.1016/j.neuropharm.2020.108359  0.4
2020 Fragale JE, James MH, Aston-Jones G. Intermittent self-administration of fentanyl induces a multifaceted addiction state associated with persistent changes in the orexin system. Addiction Biology. e12946. PMID 32798290 DOI: 10.1111/adb.12946  0.4
2020 Freeman LR, Bentzley BS, James MH, Aston-Jones G. Sex Differences in Demand for Highly Palatable Foods: Role of the Orexin System. The International Journal of Neuropsychopharmacology. PMID 32496559 DOI: 10.1093/ijnp/pyaa040  0.4
2020 James MH, Fragale JE, Aurora RN, Cooperman NA, Langleben DD, Aston-Jones G. Repurposing the dual orexin receptor antagonist suvorexant for the treatment of opioid use disorder: why sleep on this any longer? Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 31986520 DOI: 10.1038/s41386-020-0619-x  0.4
2020 James MH, Aston-Jones G. Introduction to the Special Issue: "Orexin/hypocretin receptor antagonists for the treatment of addiction and related psychiatric disease: What are the steps from here?" Brain Research. 146665. PMID 31930996 DOI: 10.1016/j.brainres.2020.146665  0.4
2019 Mohammadkhani A, Fragale JE, Pantazis CB, Bowrey HE, James MH, Aston-Jones G. Orexin-1 receptor signaling in ventral pallidum regulates motivation for the opioid remifentanil. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 31641055 DOI: 10.1523/JNEUROSCI.0255-19.2019  0.4
2019 Mohammadkhani A, James MH, Pantazis CB, Aston-Jones G. Persistent effects of the orexin-1 receptor antagonist SB-334867 on motivation for the fast acting opioid remifentanil. Brain Research. 146461. PMID 31526801 DOI: 10.1016/j.brainres.2019.146461  0.4
2019 Pantazis CB, James MH, Bentzley BS, Aston-Jones G. The number of lateral hypothalamus orexin/hypocretin neurons contributes to individual differences in cocaine demand. Addiction Biology. e12795. PMID 31297913 DOI: 10.1111/adb.12795  0.4
2019 Fragale JE, Pantazis CB, James MH, Aston-Jones G. The role of orexin-1 receptor signaling in demand for the opioid fentanyl. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 31112988 DOI: 10.1038/s41386-019-0420-x  0.4
2019 Wiskerke J, James MH, Aston-Jones G. The orexin-1 receptor antagonist SB-334867 reduces motivation, but not inhibitory control, in a rat stop signal task. Brain Research. PMID 31002819 DOI: 10.1016/j.brainres.2019.04.017  0.4
2018 Yeoh JW, James MH, Adams CD, Bains JS, Sakurai T, Aston-Jones G, Graham BA, Dayas CV. Activation of lateral hypothalamic group III mGluRs suppresses cocaine-seeking following abstinence and normalizes drug-associated increases in excitatory drive to orexin/hypocretin cells. Neuropharmacology. PMID 30253175 DOI: 10.1016/j.neuropharm.2018.09.033  0.96
2018 James MH, Bowrey HE, Stopper CM, Aston-Jones G. Demand elasticity predicts addiction endophenotypes and the therapeutic efficacy of an orexin/hypocretin-1 receptor antagonist in rats. The European Journal of Neuroscience. PMID 30240516 DOI: 10.1111/ejn.14166  0.4
2018 James MH, Stopper CM, Zimmer BA, Koll NE, Bowrey HE, Aston-Jones G. Increased Number and Activity of a Lateral Subpopulation of Hypothalamic Orexin/Hypocretin Neurons Underlies the Expression of an Addicted State in Rats. Biological Psychiatry. PMID 30219208 DOI: 10.1016/j.biopsych.2018.07.022  0.4
2017 James MH, McGlinchey EM, Vattikonda A, Mahler SV, Aston-Jones G. Cued reinstatement of cocaine- but not sucrose-seeking is dependent upon dopamine signaling in prelimbic cortex and is associated with recruitment of prelimbic neurons that project to contralateral nucleus accumbens core. The International Journal of Neuropsychopharmacology. PMID 29165565 DOI: 10.1093/ijnp/pyx107  0.4
2017 Quinn RK, James MH, Hawkins GE, Brown AL, Heathcote A, Smith DW, Cairns MJ, Dayas CV. Temporally specific miRNA expression patterns in the dorsal and ventral striatum of addiction-prone rats. Addiction Biology. PMID 28612502 DOI: 10.1111/adb.12520  0.96
2017 Bowrey HE, James MH, Aston-Jones G. New directions for the treatment of depression: Targeting the photic regulation of arousal and mood (PRAM) pathway. Depression and Anxiety. PMID 28489327 DOI: 10.1002/da.22635  0.4
2017 James MH, Aston-Jones G. Orexin/Hypocretin, Central Amygdala, and Escalation of Cocaine Intake. Biological Psychiatry. 81: 552-553. PMID 28283054 DOI: 10.1016/j.biopsych.2017.01.010  0.4
2017 James MH, Campbell EJ, Dayas CV. Role of the Orexin/Hypocretin System in Stress-Related Psychiatric Disorders. Current Topics in Behavioral Neurosciences. PMID 28083790 DOI: 10.1007/7854_2016_56  0.96
2016 James MH, Mahler SV, Moorman DE, Aston-Jones G. A Decade of Orexin/Hypocretin and Addiction: Where Are We Now? Current Topics in Behavioral Neurosciences. PMID 28012090 DOI: 10.1007/7854_2016_57  0.4
2016 Moorman DE, James MH, Kilroy EA, Aston-Jones G. Orexin/hypocretin-1 receptor antagonism reduces ethanol self-administration and reinstatement selectively in highly-motivated rats. Brain Research. PMID 27771284 DOI: 10.1016/j.brainres.2016.10.018  0.4
2016 James MH, Aston-Jones G. The Ventral Pallidum: Proposed Integrator of Positive and Negative Factors in Cocaine Abuse. Neuron. 92: 5-8. PMID 27710789 DOI: 10.1016/j.neuron.2016.09.042  0.4
2016 McGlinchey EM, James MH, Mahler SV, Pantazis C, Aston-Jones G. Prelimbic to Accumbens Core Pathway Is Recruited in a Dopamine-Dependent Manner to Drive Cued Reinstatement of Cocaine Seeking. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 8700-11. PMID 27535915 DOI: 10.1523/JNEUROSCI.1291-15.2016  0.64
2016 James MH, Quinn R, Ong LK, Levi EM, Smith DW, Dickson PW, Dayas CV. Rapamycin reduces motivated responding for cocaine and alters GluA1 expression inthe ventral but not dorsal striatum. European Journal of Pharmacology. PMID 27181066 DOI: 10.1016/j.ejphar.2016.05.013  0.64
2016 Moorman DE, James MH, Kilroy EA, Aston-Jones G. Orexin/hypocretin neuron activation is correlated with alcohol seeking and preference in a topographically specific manner. The European Journal of Neuroscience. PMID 26750264 DOI: 10.1111/ejn.13170  0.4
2014 Moorman DE, James MH, McGlinchey EM, Aston-Jones G. Differential roles of medial prefrontal subregions in the regulation of drug seeking. Brain Research. PMID 25529632 DOI: 10.1016/j.brainres.2014.12.024  0.4
2014 Yeoh JW, James MH, Graham BA, Dayas CV. Electrophysiological characteristics of paraventricular thalamic (PVT) neurons in response to cocaine and cocaine- and amphetamine-regulated transcript (CART). Frontiers in Behavioral Neuroscience. 8: 280. PMID 25309361 DOI: 10.3389/fnbeh.2014.00280  0.64
2014 Mahler SV, Moorman DE, Smith RJ, James MH, Aston-Jones G. Motivational activation: a unifying hypothesis of orexin/hypocretin function. Nature Neuroscience. 17: 1298-303. PMID 25254979 DOI: 10.1038/nn.3810  0.64
2014 James MH, Campbell EJ, Walker FR, Smith DW, Richardson HN, Hodgson DM, Dayas CV. Exercise reverses the effects of early life stress on orexin cell reactivity in male but not female rats. Frontiers in Behavioral Neuroscience. 8: 244. PMID 25100956 DOI: 10.3389/fnbeh.2014.00244  0.64
2014 Zouikr I, James MH, Campbell EJ, Clifton VL, Beagley KW, Dayas CV, Hodgson DM. Altered formalin-induced pain and Fos induction in the periaqueductal grey of preadolescent rats following neonatal LPS exposure. Plos One. 9: e98382. PMID 24878577 DOI: 10.1371/journal.pone.0098382  0.64
2014 Yeoh JW, Campbell EJ, James MH, Graham BA, Dayas CV. Orexin antagonists for neuropsychiatric disease: progress and potential pitfalls. Frontiers in Neuroscience. 8: 36. PMID 24616658 DOI: 10.3389/fnins.2014.00036  0.64
2014 James MH, Quinn RK, Ong LK, Levi EM, Charnley JL, Smith DW, Dickson PW, Dayas CV. mTORC1 inhibition in the nucleus accumbens 'protects' against the expression of drug seeking and 'relapse' and is associated with reductions in GluA1 AMPAR and CAMKIIα levels. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 1694-702. PMID 24469593 DOI: 10.1038/npp.2014.16  0.64
2014 Walker FR, James MH, Hickie IB, McGorry PD. Clinical staging: a necessary step in the development of improved animal models of mood disturbance? The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 17: 491-5. PMID 24128407 DOI: 10.1017/S1461145713001107  0.64
2013 James MH, Dayas CV. What about me…? The PVT: a role for the paraventricular thalamus (PVT) in drug-seeking behavior. Frontiers in Behavioral Neuroscience. 7: 18. PMID 23509439 DOI: 10.3389/fnbeh.2013.00018  0.64
2012 Yeoh JW, James MH, Jobling P, Bains JS, Graham BA, Dayas CV. Cocaine potentiates excitatory drive in the perifornical/lateral hypothalamus. The Journal of Physiology. 590: 3677-89. PMID 22641785 DOI: 10.1113/jphysiol.2012.230268  0.64
2011 James MH, Charnley JL, Flynn JR, Smith DW, Dayas CV. Propensity to 'relapse' following exposure to cocaine cues is associated with the recruitment of specific thalamic and epithalamic nuclei. Neuroscience. 199: 235-42. PMID 21985936 DOI: 10.1016/j.neuroscience.2011.09.047  0.64
2011 James MH, Charnley JL, Levi EM, Jones E, Yeoh JW, Smith DW, Dayas CV. Orexin-1 receptor signalling within the ventral tegmental area, but not the paraventricular thalamus, is critical to regulating cue-induced reinstatement of cocaine-seeking. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 14: 684-90. PMID 21447232 DOI: 10.1017/S1461145711000423  0.64
2010 James MH, Charnley JL, Jones E, Levi EM, Yeoh JW, Flynn JR, Smith DW, Dayas CV. Cocaine- and amphetamine-regulated transcript (CART) signaling within the paraventricular thalamus modulates cocaine-seeking behaviour. Plos One. 5: e12980. PMID 20886038 DOI: 10.1371/journal.pone.0012980  0.64
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