Stephen V. Mahler, Ph.D. - Publications

Neurobiology and Behavior University of California, Irvine, Irvine, CA 
Behavioral neuroscience, addiction, pleasure, motivation, desire, opioid, dopamine, cannabinoid

38 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Brodnik ZD, Xu W, Batra A, Lewandowski SI, Ruiz CM, Mortensen OV, Kortagere S, Mahler SV, España RA. Chemogenetic manipulation of dopamine neurons dictates cocaine potency at distal dopamine transporters. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 33046544 DOI: 10.1523/JNEUROSCI.0894-20.2020  1
2020 Ruiz CM, Torrens A, Castillo E, Perrone CR, Cevallos J, Inshishian VC, Harder EV, Justeson DN, Huestis MA, Swarup V, Piomelli D, Mahler SV. Pharmacokinetic, behavioral, and brain activity effects of Δ-tetrahydrocannabinol in adolescent male and female rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 32927465 DOI: 10.1038/s41386-020-00839-w  1
2020 Torrens A, Vozella V, Huff H, McNeil B, Ahmed F, Ghidini A, Mahler SV, Huestis MA, Das A, Piomelli D. Comparative Pharmacokinetics of Δ-Tetrahydrocannabinol in Adolescent and Adult Male Mice. The Journal of Pharmacology and Experimental Therapeutics. PMID 32345621 DOI: 10.1124/jpet.120.265892  0.16
2020 James MH, Mahler SV. Do striatal push/pull circuits hold the key to compulsive, relapsing heroin addiction? : A Research Highlight on: Chemogenetic modulation of accumbens direct or indirect pathways bidirectionally alters reinstatement of heroin-seeking in high- but not low-risk rats, by O'Neal et al. (2019). Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 31974443 DOI: 10.1038/s41386-020-0615-1  1
2019 Levis SC, Bentzley BS, Molet J, Bolton JL, Perrone CR, Baram TZ, Mahler SV. On the early life origins of vulnerability to opioid addiction. Molecular Psychiatry. PMID 31822817 DOI: 10.1038/s41380-019-0628-5  1
2019 Bonaventura J, Eldridge MAG, Hu F, Gomez JL, Sanchez-Soto M, Abramyan AM, Lam S, Boehm MA, Ruiz C, Farrell MR, Moreno A, Galal Faress IM, Andersen N, Lin JY, Moaddel R, ... ... Mahler SV, et al. High-potency ligands for DREADD imaging and activation in rodents and monkeys. Nature Communications. 10: 4627. PMID 31604917 DOI: 10.1038/s41467-019-12236-z  1
2019 Farrell MR, Ruiz CM, Castillo E, Faget L, Khanbijian C, Liu S, Schoch H, Rojas G, Huerta MY, Hnasko TS, Mahler SV. Ventral pallidum is essential for cocaine relapse after voluntary abstinence in rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 31476762 DOI: 10.1038/s41386-019-0507-4  1
2019 Jayachandran M, Linley SB, Schlecht M, Mahler SV, Vertes RP, Allen TA. Prefrontal Pathways Provide Top-Down Control of Memory for Sequences of Events. Cell Reports. 28: 640-654.e6. PMID 31315044 DOI: 10.1016/j.celrep.2019.06.053  0.01
2019 Halbout B, Marshall AT, Azimi A, Liljeholm M, Mahler SV, Wassum KM, Ostlund SB. Mesolimbic dopamine projections mediate cue-motivated reward seeking but not reward retrieval in rats. Elife. 8. PMID 31107241 DOI: 10.7554/eLife.43551  0.01
2018 Mahler SV, Brodnik ZD, Cox BM, Buchta WC, Bentzley BS, Quintanilla J, Cope ZA, Lin EC, Riedy MD, Scofield MD, Messinger J, Ruiz CM, Riegel AC, España RA, Aston-Jones G. Chemogenetic Manipulations of Ventral Tegmental Area Dopamine Neurons Reveal Multifaceted Roles in Cocaine Abuse. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 30446532 DOI: 10.1523/JNEUROSCI.0537-18.2018  1
2018 Mitchell MR, Berridge KC, Mahler SV. Endocannabinoid-Enhanced "Liking" in Nucleus Accumbens Shell Hedonic Hotspot Requires Endogenous Opioid Signals. Cannabis and Cannabinoid Research. 3: 166-170. PMID 30069500 DOI: 10.1089/can.2018.0021  1
2018 Bolton JL, Ruiz CM, Rismanchi N, Sanchez GA, Castillo E, Huang J, Cross C, Baram TZ, Mahler SV. Early-life adversity facilitates acquisition of cocaine self-administration and induces persistent anhedonia. Neurobiology of Stress. 8: 57-67. PMID 29888304 DOI: 10.1016/j.ynstr.2018.01.002  1
2018 Mahler SV. Author Correction: Stay alert, don't get hurt. Nature Neuroscience. PMID 29752480 DOI: 10.1038/s41593-018-0111-7  0.01
2018 Farrell MR, Schoch H, Mahler SV. Modeling cocaine relapse in rodents: Behavioral considerations and circuit mechanisms. Progress in Neuro-Psychopharmacology & Biological Psychiatry. PMID 29305936 DOI: 10.1016/j.pnpbp.2018.01.002  1
2018 Mahler SV, Aston-Jones G. CNO Evil? Considerations for the Use of DREADDs in Behavioral Neuroscience. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 29303143 DOI: 10.1038/npp.2017.299  1
2018 Mahler SV. Stay alert, don't get hurt. Nature Neuroscience. 21: 3-5. PMID 29269760 DOI: 10.1038/s41593-017-0045-5  0.01
2017 James MH, McGlinchey EM, Vattikonda A, Mahler SV, Aston-Jones G. Cued reinstatement of cocaine- but not sucrose-seeking is dependent upon dopamine signaling in prelimbic cortex and is associated with recruitment of prelimbic neurons that project to contralateral nucleus accumbens core. The International Journal of Neuropsychopharmacology. PMID 29165565 DOI: 10.1093/ijnp/pyx107  1
2017 Schoch H, Huerta MY, Ruiz CM, Farrell MR, Jung KM, Huang JJ, Campbell RR, Piomelli D, Mahler SV. Adolescent cannabinoid exposure effects on natural reward seeking and learning in rats. Psychopharmacology. PMID 29022083 DOI: 10.1007/s00213-017-4749-8  1
2017 Buchta WC, Mahler SV, Harlan B, Aston-Jones GS, Riegel AC. Dopamine terminals from the ventral tegmental area gate intrinsic inhibition in the prefrontal cortex. Physiological Reports. 5. PMID 28325790 DOI: 10.14814/phy2.13198  1
2016 James MH, Mahler SV, Moorman DE, Aston-Jones G. A Decade of Orexin/Hypocretin and Addiction: Where Are We Now? Current Topics in Behavioral Neurosciences. PMID 28012090 DOI: 10.1007/7854_2016_57  1
2016 McGlinchey EM, James MH, Mahler SV, Pantazis C, Aston-Jones G. Prelimbic to Accumbens Core Pathway Is Recruited in a Dopamine-Dependent Manner to Drive Cued Reinstatement of Cocaine Seeking. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 8700-11. PMID 27535915 DOI: 10.1523/JNEUROSCI.1291-15.2016  1
2016 Smith KS, Bucci DJ, Luikart BW, Mahler SV. DREADDs: Use and Application in Behavioral Neuroscience. Behavioral Neuroscience. PMID 26913540 DOI: 10.1037/bne0000135  1
2014 Mahler SV, Moorman DE, Smith RJ, James MH, Aston-Jones G. Motivational activation: a unifying hypothesis of orexin/hypocretin function. Nature Neuroscience. 17: 1298-303. PMID 25254979 DOI: 10.1038/nn.3810  1
2014 Mahler SV, Vazey EM, Beckley JT, Keistler CR, McGlinchey EM, Kaufling J, Wilson SP, Deisseroth K, Woodward JJ, Aston-Jones G. Designer receptors show role for ventral pallidum input to ventral tegmental area in cocaine seeking. Nature Neuroscience. 17: 577-85. PMID 24584054 DOI: 10.1038/nn.3664  1
2014 Mahler SV, Hensley-Simon M, Tahsili-Fahadan P, LaLumiere RT, Thomas C, Fallon RV, Kalivas PW, Aston-Jones G. Modafinil attenuates reinstatement of cocaine seeking: role for cystine-glutamate exchange and metabotropic glutamate receptors. Addiction Biology. 19: 49-60. PMID 23017017 DOI: 10.1111/j.1369-1600.2012.00506.x  1
2013 Mahler SV, Moorman DE, Feltenstein MW, Cox BM, Ogburn KB, Bachar M, McGonigal JT, Ghee SM, See RE. A rodent "self-report" measure of methamphetamine craving? Rat ultrasonic vocalizations during methamphetamine self-administration, extinction, and reinstatement. Behavioural Brain Research. 236: 78-89. PMID 22940018 DOI: 10.1016/j.bbr.2012.08.023  1
2013 Mahler SV, Smith RJ, Aston-Jones G. Interactions between VTA orexin and glutamate in cue-induced reinstatement of cocaine seeking in rats. Psychopharmacology. 226: 687-98. PMID 22411428 DOI: 10.1007/s00213-012-2681-5  1
2012 Mahler SV, Aston-Jones GS. Fos activation of selective afferents to ventral tegmental area during cue-induced reinstatement of cocaine seeking in rats. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 13309-26. PMID 22993446 DOI: 10.1523/JNEUROSCI.2277-12.2012  1
2012 Mahler SV, Smith RJ, Moorman DE, Sartor GC, Aston-Jones G. Multiple roles for orexin/hypocretin in addiction. Progress in Brain Research. 198: 79-121. PMID 22813971 DOI: 10.1016/B978-0-444-59489-1.00007-0  1
2012 Mahler SV, Berridge KC. What and when to "want"? Amygdala-based focusing of incentive salience upon sugar and sex. Psychopharmacology. 221: 407-26. PMID 22167254 DOI: 10.1007/s00213-011-2588-6  1
2010 Mahler SV, de Wit H. Cue-reactors: individual differences in cue-induced craving after food or smoking abstinence. Plos One. 5: e15475. PMID 21085667 DOI: 10.1371/journal.pone.0015475  1
2009 Mahler SV, Berridge KC. Which cue to "want?" Central amygdala opioid activation enhances and focuses incentive salience on a prepotent reward cue. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 6500-13. PMID 19458221 DOI: 10.1523/JNEUROSCI.3875-08.2009  1
2007 Mahler SV, Smith KS, Berridge KC. Endocannabinoid hedonic hotspot for sensory pleasure: anandamide in nucleus accumbens shell enhances 'liking' of a sweet reward. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 32: 2267-78. PMID 17406653 DOI: 10.1038/sj.npp.1301376  1
2006 Acheson A, Mahler SV, Chi H, de Wit H. Differential effects of nicotine on alcohol consumption in men and women. Psychopharmacology. 186: 54-63. PMID 16565827 DOI: 10.1007/s00213-006-0338-y  1
2005 Alsene KM, Mahler SV, de Wit H. Effects of d-amphetamine and smoking abstinence on cue-induced cigarette craving. Experimental and Clinical Psychopharmacology. 13: 209-18. PMID 16173884 DOI: 10.1037/1064-1297.13.3.209  1
2005 Mahler SV, de Wit H. Effects of haloperidol on reactions to smoking cues in humans. Behavioural Pharmacology. 16: 123-6. PMID 15767848 DOI: 10.1097/00008877-200503000-00008  1
2005 Young EM, Mahler S, Chi H, de Wit H. Mecamylamine and ethanol preference in healthy volunteers. Alcoholism, Clinical and Experimental Research. 29: 58-65. PMID 15654292 DOI: 10.1097/01.ALC.0000150007.34702.16  1
2003 Roney JR, Mahler SV, Maestripieri D. Behavioral and hormonal responses of men to brief interactions with women Evolution and Human Behavior. 24: 365-375. DOI: 10.1016/S1090-5138(03)00053-9  1
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