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Rebecca Lock, Ph.D. - Publications

Affiliations: 
2012 Biomedical Sciences University of California, San Francisco, San Francisco, CA 
Area:
Cell Biology, Oncology
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11 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Perurena N, Lock R, Davis RA, Raghavan S, Pilla NF, Ng R, Loi P, Guild CJ, Miller AL, Sicinska E, Cleary JM, Rubinson DA, Wolpin BM, Gray NS, Santagata S, et al. USP9X mediates an acute adaptive response to MAPK suppression in pancreatic cancer but creates multiple actionable therapeutic vulnerabilities. Cell Reports. Medicine. 101007. PMID 37030295 DOI: 10.1016/j.xcrm.2023.101007  0.373
2020 Tian T, Lofftus S, Pan Y, Stingley CA, King SL, Zhao J, Pan TY, Lock R, Marglous JW, Liu K, Widlund HR, Fuhlbrigge RC, Cichowski K, Kupper TS. IL1α antagonizes IL1β and promotes adaptive immune rejection of malignant tumors. Cancer Immunology Research. PMID 32161110 DOI: 10.1158/2326-6066.Cir-19-0552  0.301
2017 Lock R, Ingraham R, Maertens O, Konicek B, Yan S, Graff J, Cichowski K. Abstract A18: Targeting the MNK kinases for the treatment of NF1-mutant cancers Clinical Cancer Research. 23. DOI: 10.1158/1557-3265.Pmccavuln16-A18  0.427
2016 Lock R, Ingraham R, Maertens O, Miller AL, Weledji N, Legius E, Konicek BM, Yan SB, Graff JR, Cichowski K. Cotargeting MNK and MEK kinases induces the regression of NF1-mutant cancers. The Journal of Clinical Investigation. PMID 27159396 DOI: 10.1172/Jci85183  0.441
2015 Lock R, Cichowski K. Loss of negative regulators amplifies RAS signaling. Nature Genetics. 47: 426-7. PMID 25916896 DOI: 10.1038/Ng.3299  0.393
2014 Lock R, Kenific CM, Leidal AM, Salas E, Debnath J. Autophagy-dependent production of secreted factors facilitates oncogenic RAS-driven invasion. Cancer Discovery. 4: 466-79. PMID 24513958 DOI: 10.1158/2159-8290.Cd-13-0841  0.493
2013 Chen N, Eritja N, Lock R, Debnath J. Autophagy restricts proliferation driven by oncogenic phosphatidylinositol 3-kinase in three-dimensional culture Oncogene. 32: 2543-2554. PMID 22777351 DOI: 10.1038/Onc.2012.277  0.433
2011 Lock R, Debnath J. Ras, autophagy and glycolysis. Cell Cycle (Georgetown, Tex.). 10: 1516-7. PMID 21467842 DOI: 10.4161/Cc.10.10.15434  0.376
2011 Lock R, Roy S, Kenific CM, Su JS, Salas E, Ronen SM, Debnath J. Autophagy facilitates glycolysis during Ras-mediated oncogenic transformation. Molecular Biology of the Cell. 22: 165-78. PMID 21119005 DOI: 10.1091/Mbc.E10-06-0500  0.457
2008 Lock R, Debnath J. Extracellular matrix regulation of autophagy. Current Opinion in Cell Biology. 20: 583-8. PMID 18573652 DOI: 10.1016/J.Ceb.2008.05.002  0.428
2008 Fung C, Lock R, Gao S, Salas E, Debnath J. Induction of autophagy during extracellular matrix detachment promotes cell survival. Molecular Biology of the Cell. 19: 797-806. PMID 18094039 DOI: 10.1091/Mbc.E07-10-1092  0.388
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