Simon-Pierre Gravel, Ph.D. - Publications

Affiliations: 
2010 Université de Montréal, Montréal, Canada 
Area:
Molecular Biology

20/32 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Mellal K, Omri S, Mulumba M, Tahiri H, Fortin C, Dorion MF, Pham H, Garcia Ramos Y, Zhang J, Pundir S, Joyal JS, Bouchard JF, Sennlaub F, Febbraio M, Hardy P, ... Gravel SP, et al. Immunometabolic modulation of retinal inflammation by CD36 ligand. Scientific Reports. 9: 12903. PMID 31501473 DOI: 10.1038/S41598-019-49472-8  0.343
2018 Hulea L, Gravel SP, Morita M, Cargnello M, Uchenunu O, Im YK, Lehuédé C, Ma EH, Leibovitch M, McLaughlan S, Blouin MJ, Parisotto M, Papavasiliou V, Lavoie C, Larsson O, et al. Translational and HIF-1α-Dependent Metabolic Reprogramming Underpin Metabolic Plasticity and Responses to Kinase Inhibitors and Biguanides. Cell Metabolism. PMID 30244971 DOI: 10.1016/J.Cmet.2018.09.001  0.39
2018 Shamalnasab M, Gravel SP, St-Pierre J, Breton L, Jäger S, Aguilaniu H. A salicylic acid derivative extends the lifespan of Caenorhabditis elegans by activating autophagy and the mitochondrial unfolded protein response. Aging Cell. e12830. PMID 30192051 DOI: 10.1111/Acel.12830  0.375
2018 Im YK, Najyb O, Gravel SP, McGuirk S, Ahn R, Avizonis D, Chénard V, Sabourin V, Hudson J, Pawson T, Topisirovic I, Pollak MN, St-Pierre J, Ursini-Siegel J. Interplay between ShcA signaling and PGC-1α triggers targetable metabolic vulnerabilities in breast cancer. Cancer Research. PMID 29930100 DOI: 10.1158/0008-5472.Can-17-3696  0.357
2018 Gravel SP. Deciphering the Dichotomous Effects of PGC-1α on Tumorigenesis and Metastasis. Frontiers in Oncology. 8: 75. PMID 29629336 DOI: 10.3389/Fonc.2018.00075  0.367
2018 Houles T, Gravel SP, Lavoie G, Shin S, Savall M, Méant A, Grondin B, Gaboury L, Yoon SO, St-Pierre J, Roux PP. RSK Regulates PFK-2 Activity to Promote Metabolic Rewiring in Melanoma. Cancer Research. PMID 29440170 DOI: 10.1158/0008-5472.Can-17-2215  0.501
2017 Rabinovitch RC, Samborska B, Faubert B, Ma EH, Gravel SP, Andrzejewski S, Raissi TC, Pause A, St-Pierre J, Jones RG. AMPK Maintains Cellular Metabolic Homeostasis through Regulation of Mitochondrial Reactive Oxygen Species. Cell Reports. 21: 1-9. PMID 28978464 DOI: 10.1016/J.Celrep.2017.09.026  0.325
2017 Hulea L, Cargnello M, Gravel S, Im Y, McLaughlan S, Zhao Y, Ching J, Cai Y, Larsson O, Ohh M, Ursini-Siegel J, St-Pierre J, Pollak M, Topisirovic I. Abstract A31: eIF4F links translation to energy stress response in cancer Cancer Research. 77. DOI: 10.1158/1538-7445.Transcontrol16-A31  0.38
2016 Deblois G, Smith HW, Tam IS, Gravel SP, Caron M, Savage P, Labbé DP, Bégin LR, Tremblay ML, Park M, Bourque G, St-Pierre J, Muller WJ, Giguère V. ERRα mediates metabolic adaptations driving lapatinib resistance in breast cancer. Nature Communications. 7: 12156. PMID 27402251 DOI: 10.1038/Ncomms12156  0.334
2016 Audet-Walsh É, Papadopoli DJ, Gravel SP, Yee T, Bridon G, Caron M, Bourque G, Giguère V, St-Pierre J. The PGC-1α/ERRα Axis Represses One-Carbon Metabolism and Promotes Sensitivity to Anti-folate Therapy in Breast Cancer. Cell Reports. PMID 26804918 DOI: 10.1016/J.Celrep.2015.12.086  0.364
2014 Gravel SP, Hulea L, Toban N, Birman E, Blouin MJ, Zakikhani M, Zhao Y, Topisirovic I, St-Pierre J, Pollak M. Serine deprivation enhances antineoplastic activity of biguanides. Cancer Research. 74: 7521-33. PMID 25377470 DOI: 10.1158/0008-5472.Can-14-2643-T  0.429
2014 Andrzejewski S, Gravel S, St-Pierre J, Pollak MN. Dual mode of action of metformin on mitochondrial metabolism Cancer & Metabolism. 2. DOI: 10.1186/2049-3002-2-S1-P4  0.315
2013 McGuirk S, Gravel SP, Deblois G, Papadopoli DJ, Faubert B, Wegner A, Hiller K, Avizonis D, Akavia UD, Jones RG, Giguère V, St-Pierre J. PGC-1α supports glutamine metabolism in breast cancer. Cancer & Metabolism. 1: 22. PMID 24304688 DOI: 10.1186/2049-3002-1-22  0.304
2009 Gravel S, Richard DE, Servant MJ. Role of the IKK-related kinases in the induction of HIF-1α during hypoxia Cytokine. 48: 54. DOI: 10.1016/J.Cyto.2009.07.159  0.663
2008 Clément JF, Bibeau-Poirier A, Gravel SP, Grandvaux N, Bonneil E, Thibault P, Meloche S, Servant MJ. Phosphorylation of IRF-3 on Ser 339 generates a hyperactive form of IRF-3 through regulation of dimerization and CBP association. Journal of Virology. 82: 3984-96. PMID 18272581 DOI: 10.1128/Jvi.02526-07  0.681
2008 Gravel S, Richard DE, Servant MJ. 185 IKK-related kinases are repressors of HIF-1 transcriptional activity Cytokine. 43: 283. DOI: 10.1016/J.Cyto.2008.07.247  0.698
2006 Bibeau-Poirier A, Gravel SP, Clément JF, Rolland S, Rodier G, Coulombe P, Hiscott J, Grandvaux N, Meloche S, Servant MJ. Involvement of the IkappaB kinase (IKK)-related kinases tank-binding kinase 1/IKKi and cullin-based ubiquitin ligases in IFN regulatory factor-3 degradation. Journal of Immunology (Baltimore, Md. : 1950). 177: 5059-67. PMID 17015689 DOI: 10.4049/Jimmunol.177.8.5059  0.684
2006 Douillette A, Bibeau-Poirier A, Gravel SP, Clément JF, Chénard V, Moreau P, Servant MJ. The proinflammatory actions of angiotensin II are dependent on p65 phosphorylation by the IkappaB kinase complex. The Journal of Biological Chemistry. 281: 13275-84. PMID 16513650 DOI: 10.1074/Jbc.M512815200  0.665
2005 Gravel SP, Servant MJ. Roles of an IkappaB kinase-related pathway in human cytomegalovirus-infected vascular smooth muscle cells: a molecular link in pathogen-induced proatherosclerotic conditions. The Journal of Biological Chemistry. 280: 7477-86. PMID 15619605 DOI: 10.1074/Jbc.M410392200  0.713
2000 Ahnadi CE, Giguère P, Gravel S, Gagné D, Goulet AC, Fülöp T, Payet MD, Dupuis G. Chronic PMA treatment of Jurkat T lymphocytes results in decreased protein tyrosine phosphorylation and inhibition of CD3- but not Ti-dependent antibody-triggered Ca2+ signaling Journal of Leukocyte Biology. 68: 293-300. PMID 10947075 DOI: 10.1189/Jlb.68.2.293  0.355
Low-probability matches (unlikely to be authored by this person)
2017 Uetani N, Hardy S, Gravel SP, Kiessling S, Pietrobon A, Wong NN, Chénard V, Cermakian N, St-Pierre J, Tremblay ML. PRL2 links magnesium flux and sex-dependent circadian metabolic rhythms. Jci Insight. 2. PMID 28679948 DOI: 10.1172/Jci.Insight.91722  0.299
2014 Gravel SP, Andrzejewski S, Avizonis D, St-Pierre J. Stable isotope tracer analysis in isolated mitochondria from mammalian systems. Metabolites. 4: 166-83. PMID 24957021 DOI: 10.3390/Metabo4020166  0.291
2018 Thivierge C, Tseng HW, Mayya VK, Lussier C, Gravel SP, Duchaine TF. Alternative polyadenylation confers Pten mRNAs stability and resistance to microRNAs. Nucleic Acids Research. PMID 30053103 DOI: 10.1093/Nar/Gky666  0.281
2016 Gravel SP, Avizonis D, St-Pierre J. Metabolomics Analyses of Cancer Cells in Controlled Microenvironments. Methods in Molecular Biology (Clifton, N.J.). 1458: 273-90. PMID 27581029 DOI: 10.1007/978-1-4939-3801-8_20  0.272
2014 Andrzejewski S, Gravel SP, Pollak M, St-Pierre J. Metformin directly acts on mitochondria to alter cellular bioenergetics. Cancer & Metabolism. 2: 12. PMID 25184038 DOI: 10.1186/2049-3002-2-12  0.249
2013 Mamer O, Gravel SP, Choinière L, Chénard V, St-Pierre J, Avizonis D. The complete targeted profile of the organic acid intermediates of the citric acid cycle using a single stable isotope dilution analysis, sodium borodeuteride reduction and selected ion monitoring GC/MS. Metabolomics : Official Journal of the Metabolomic Society. 9: 1019-1030. PMID 24348278 DOI: 10.1007/S11306-013-0521-1  0.229
2015 Morita M, Gravel SP, Hulea L, Larsson O, Pollak M, St-Pierre J, Topisirovic I. mTOR coordinates protein synthesis, mitochondrial activity and proliferation. Cell Cycle (Georgetown, Tex.). 14: 473-80. PMID 25590164 DOI: 10.4161/15384101.2014.991572  0.225
2013 Morita M, Gravel SP, Chénard V, Sikström K, Zheng L, Alain T, Gandin V, Avizonis D, Arguello M, Zakaria C, McLaughlan S, Nouet Y, Pause A, Pollak M, Gottlieb E, et al. mTORC1 controls mitochondrial activity and biogenesis through 4E-BP-dependent translational regulation. Cell Metabolism. 18: 698-711. PMID 24206664 DOI: 10.1016/J.Cmet.2013.10.001  0.215
2022 Laurin KM, Coutu-Beaudry K, Salazar A, Méribout N, Audet-Walsh É, Gravel SP. Low expression of PGC-1β and other mitochondrial biogenesis modulators in melanoma is associated with growth arrest and the induction of an immunosuppressive gene expression program dependent on MEK and IRF-1. Cancer Letters. 541: 215738. PMID 35594996 DOI: 10.1016/j.canlet.2022.215738  0.214
2023 Gravel SP, Ben Khalifa Y, McGuirk S, St-Louis C, Laurin KM, Lavallée É, Benas D, Desbouis S, Amaral F, D'Amours D, Breton L, Jäger S, St-Pierre J. PGC-1s shape epidermal physiology by modulating keratinocyte proliferation and terminal differentiation. Iscience. 26: 106314. PMID 37009228 DOI: 10.1016/j.isci.2023.106314  0.176
2016 Gandin V, Masvidal L, Hulea L, Gravel SP, Cargnello M, McLaughlan S, Cai Y, Balanathan P, Morita M, Rajakumar A, Furic L, Pollak M, Porco JA, St-Pierre J, Pelletier J, et al. nanoCAGE reveals 5' UTR features that define specific modes of translation of functionally related MTOR-sensitive mRNAs. Genome Research. PMID 26984228 DOI: 10.1101/Gr.197566.115  0.173
2022 Zadory M, Lopez E, Babity S, Gravel SP, Brambilla D. Current knowledge on the tissue distribution of mRNA nanocarriers for therapeutic protein expression. Biomaterials Science. PMID 36097955 DOI: 10.1039/d2bm00859a  0.097
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