Ali Brivanlou - Publications

Rockefeller University, New York, NY, United States 
neural development

76 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Yoney A, Bai L, Brivanlou AH, Siggia ED. Mechanisms underlying WNT-mediated priming of human embryonic stem cells. Development (Cambridge, England). 149. PMID 35815787 DOI: 10.1242/dev.200335  0.451
2022 Simunovic M, Siggia ED, Brivanlou AH. In vitro attachment and symmetry breaking of a human embryo model assembled from primed embryonic stem cells. Cell Stem Cell. 29: 962-972.e4. PMID 35659878 DOI: 10.1016/j.stem.2022.05.001  0.388
2022 Piccolo FM, Kastan NR, Haremaki T, Tian Q, Laundos TL, De Santis R, Beaudoin AJ, Carroll TS, Luo JD, Gnedeva K, Etoc F, Hudspeth AJ, Brivanlou AH. Role of YAP in early ectodermal specification and a Huntington's Disease model of human neurulation. Elife. 11. PMID 35451959 DOI: 10.7554/eLife.73075  0.383
2021 De Santis R, Etoc F, Rosado-Olivieri EA, Brivanlou AH. Self-organization of human dorsal-ventral forebrain structures by light induced SHH. Nature Communications. 12: 6768. PMID 34799555 DOI: 10.1038/s41467-021-26881-w  0.359
2021 Valet M, Siggia ED, Brivanlou AH. Mechanical regulation of early vertebrate embryogenesis. Nature Reviews. Molecular Cell Biology. PMID 34754086 DOI: 10.1038/s41580-021-00424-z  0.417
2021 Galgoczi S, Ruzo A, Markopoulos C, Yoney A, Phan-Everson T, Li S, Haremaki T, Metzger JJ, Etoc F, Brivanlou AH. Huntingtin CAG expansion impairs germ layer patterning in synthetic human 2D gastruloids through polarity defects. Development (Cambridge, England). 148. PMID 34608934 DOI: 10.1242/dev.199513  0.323
2021 De Santis R, Brivanlou AH. The treasure inside human naive pluripotency, generation of trophectoderm and blastoids. Cell Stem Cell. 28: 985-987. PMID 34087157 DOI: 10.1016/j.stem.2021.05.010  0.396
2021 Clark AT, Brivanlou A, Fu J, Kato K, Mathews D, Niakan KK, Rivron N, Saitou M, Surani A, Tang F, Rossant J. Human embryo research, stem cell-derived embryo models and in vitro gametogenesis: Considerations leading to the revised ISSCR guidelines. Stem Cell Reports. PMID 34048690 DOI: 10.1016/j.stemcr.2021.05.008  0.33
2021 Yang M, Rito T, Metzger J, Naftaly J, Soman R, Hu J, Albertini DF, Barad DH, Brivanlou AH, Gleicher N. Depletion of aneuploid cells in human embryos and gastruloids. Nature Cell Biology. 23: 314-321. PMID 33837289 DOI: 10.1038/s41556-021-00660-7  0.329
2019 Haremaki T, Metzger JJ, Rito T, Ozair MZ, Etoc F, Brivanlou AH. Self-organizing neuruloids model developmental aspects of Huntington's disease in the ectodermal compartment. Nature Biotechnology. PMID 31501559 DOI: 10.1038/S41587-019-0237-5  0.765
2019 Martyn I, Siggia ED, Brivanlou AH. Mapping cell migrations and fates in a gastruloid model to the human primitive streak. Development (Cambridge, England). 146. PMID 31427289 DOI: 10.1242/Dev.179564  0.309
2019 Simunovic M, Metzger JJ, Etoc F, Yoney A, Ruzo A, Martyn I, Croft G, You DS, Brivanlou AH, Siggia ED. A 3D model of a human epiblast reveals BMP4-driven symmetry breaking. Nature Cell Biology. 21: 900-910. PMID 31263269 DOI: 10.1038/s41556-019-0349-7  0.379
2019 Martyn I, Kanno TY, Brivanlou AH. Chick Models and Human-Chick Organizer Grafts. Methods in Molecular Biology (Clifton, N.J.). 2005: 77-89. PMID 31175647 DOI: 10.1007/978-1-4939-9524-0_6  0.399
2019 Etoc F, Brivanlou A. A boost towards totipotency for stem cells. Nature Cell Biology. 21: 671-673. PMID 31160707 DOI: 10.1038/s41556-019-0340-3  0.489
2019 Martyn I, Brivanlou AH, Siggia ED. A wave of WNT signaling balanced by secreted inhibitors controls primitive streak formation in micropattern colonies of human embryonic stem cells. Development (Cambridge, England). 146. PMID 30814117 DOI: 10.1242/Dev.172791  0.34
2018 Yoney A, Etoc F, Ruzo A, Carroll T, Metzger JJ, Martyn I, Li S, Kirst C, Siggia ED, Brivanlou AH. WNT signaling memory is required for ACTIVIN to function as a morphogen in human gastruloids. Elife. 7. PMID 30311909 DOI: 10.7554/Elife.38279  0.311
2018 Metzger JJ, Simunovic M, Brivanlou AH. Synthetic embryology: controlling geometry to model early mammalian development. Current Opinion in Genetics & Development. 52: 86-91. PMID 29957587 DOI: 10.1016/j.gde.2018.06.006  0.351
2018 Ozair MZ, Kirst C, van den Berg BL, Ruzo A, Rito T, Brivanlou AH. hPSC Modeling Reveals that Fate Selection of Cortical Deep Projection Neurons Occurs in the Subplate. Cell Stem Cell. PMID 29937203 DOI: 10.1016/J.Stem.2018.05.024  0.704
2017 Waisman A, Echegaray CV, Solari C, Cosentino MS, Martyn I, Deglincerti A, Ozair MZ, Matias AR, Barañao L, Miriuka S, Brivanlou A, Guberman A. Inhibition of cell division and DNA replication impair mouse naïve pluripotency exit. Journal of Molecular Biology. PMID 28684247 DOI: 10.1016/J.Jmb.2017.06.020  0.726
2017 Qi Y, Zhang XJ, Renier N, Wu Z, Atkin T, Sun Z, Ozair MZ, Tchieu J, Zimmer B, Fattahi F, Ganat Y, Azevedo R, Zeltner N, Brivanlou AH, Karayiorgou M, et al. Combined small-molecule inhibition accelerates the derivation of functional cortical neurons from human pluripotent stem cells. Nature Biotechnology. PMID 28112759 DOI: 10.1038/Nbt.3777  0.721
2017 Kanno TYN, Yan CYI, Brivanlou A. Role of Scratch2 in mouse embryonic stem cells cortical differentiation Mechanisms of Development. 145: S175. DOI: 10.1016/j.mod.2017.04.509  0.475
2016 Etoc F, Metzger J, Ruzo A, Kirst C, Yoney A, Ozair MZ, Brivanlou AH, Siggia ED. A Balance between Secreted Inhibitors and Edge Sensing Controls Gastruloid Self-Organization. Developmental Cell. PMID 27746044 DOI: 10.1016/J.Devcel.2016.09.016  0.751
2016 Deglincerti A, Etoc F, Guerra MC, Martyn I, Metzger J, Ruzo A, Simunovic M, Yoney A, Brivanlou AH, Siggia E, Warmflash A. Self-organization of human embryonic stem cells on micropatterns. Nature Protocols. 11: 2223-2232. PMID 27735934 DOI: 10.1038/Nprot.2016.131  0.401
2016 Deglincerti A, Croft GF, Pietila LN, Zernicka-Goetz M, Siggia ED, Brivanlou AH. Self-organization of the in vitro attached human embryo. Nature. PMID 27144363 DOI: 10.1038/Nature17948  0.406
2016 Deglincerti A, Etoc F, Ozair MZ, Brivanlou AH. Self-Organization of Spatial Patterning in Human Embryonic Stem Cells. Current Topics in Developmental Biology. 116: 99-113. PMID 26970615 DOI: 10.1016/Bs.Ctdb.2015.11.010  0.737
2016 Sato N, Brivanlou A. Microarray Approach to Identify the Signaling Network Responsible for Self-Renewal of Human Embryonic Stem Cells. Methods in Molecular Biology (Clifton, N.J.). 1307: 71-88. PMID 25990842 DOI: 10.1007/7651_2015_244  0.329
2016 Deglincerti A, Etoc F, Ozair MZ, Brivanlou AH. Self-Organization of Spatial Patterning in Human Embryonic Stem Cells Current Topics in Developmental Biology. DOI: 10.1016/bs.ctdb.2015.11.010  0.731
2015 Deglincerti A, Brivanlou AH. The generation of sex cells. Cell Research. 25: 267-8. PMID 25698577 DOI: 10.1038/Cr.2015.18  0.372
2014 Warmflash A, Sorre B, Etoc F, Siggia ED, Brivanlou AH. A method to recapitulate early embryonic spatial patterning in human embryonic stem cells. Nature Methods. 11: 847-54. PMID 24973948 DOI: 10.1038/Nmeth.3016  0.417
2013 Bates TJ, Vonica A, Heasman J, Brivanlou AH, Bell E. Coco regulates dorsoventral specification of germ layers via inhibition of TGFβ signalling. Development (Cambridge, England). 140: 4177-81. PMID 24026124 DOI: 10.1242/Dev.095521  0.312
2013 Ozair MZ, Kintner C, Brivanlou AH. Neural induction and early patterning in vertebrates. Wiley Interdisciplinary Reviews. Developmental Biology. 2: 479-98. PMID 24014419 DOI: 10.1002/Wdev.90  0.781
2013 Rosa A, Brivanlou AH. Regulatory non-coding RNAs in pluripotent stem cells. International Journal of Molecular Sciences. 14: 14346-73. PMID 23852015 DOI: 10.3390/ijms140714346  0.346
2013 Ozair MZ, Noggle S, Warmflash A, Krzyspiak JE, Brivanlou AH. SMAD7 directly converts human embryonic stem cells to telencephalic fate by a default mechanism. Stem Cells (Dayton, Ohio). 31: 35-47. PMID 23034881 DOI: 10.1002/Stem.1246  0.768
2013 Singh H, Brivanlou AH. The Molecular Circuitry Underlying Pluripotency in Embryonic Stem Cells and iPS Cells Handbook of Stem Cells. 1: 29-35. DOI: 10.1016/B978-0-12-385942-6.00005-6  0.346
2012 Warmflash A, Siggia ED, Brivanlou AH. Signaling dynamics and embryonic development. Cell Cycle (Georgetown, Tex.). 11: 3529-30. PMID 22935712 DOI: 10.4161/Cc.21964  0.316
2012 Arduini BL, Brivanlou AH. Modulation of FOXD3 activity in human embryonic stem cells directs pluripotency and paraxial mesoderm fates. Stem Cells (Dayton, Ohio). 30: 2188-98. PMID 22887036 DOI: 10.1002/Stem.1200  0.437
2012 Warmflash A, Arduini BL, Brivanlou AH. The molecular circuitry underlying pluripotency in embryonic stem cells. Wiley Interdisciplinary Reviews. Systems Biology and Medicine. 4: 443-56. PMID 22761038 DOI: 10.1002/Wsbm.1182  0.413
2011 Rosa A, Brivanlou AH. A regulatory circuitry comprised of miR-302 and the transcription factors OCT4 and NR2F2 regulates human embryonic stem cell differentiation. The Embo Journal. 30: 237-48. PMID 21151097 DOI: 10.1038/emboj.2010.319  0.329
2011 Arduini B, Brivanlou AH. Role of FoxD3 in maintenance of pluripotency and early lineage segregation in human embryonic stem cells Developmental Biology. 356: 214. DOI: 10.1016/J.Ydbio.2011.05.327  0.402
2010 Shimomura Y, Agalliu D, Vonica A, Luria V, Wajid M, Baumer A, Belli S, Petukhova L, Schinzel A, Brivanlou AH, Barres BA, Christiano AM. APCDD1 is a novel Wnt inhibitor mutated in hereditary hypotrichosis simplex. Nature. 464: 1043-7. PMID 20393562 DOI: 10.1038/Nature08875  0.326
2009 Rosa A, Brivanlou AH. MicroRNAs in early vertebrate development. Cell Cycle (Georgetown, Tex.). 8: 3513-20. PMID 19875943  0.363
2009 Lacoste A, Berenshteyn F, Brivanlou AH. An efficient and reversible transposable system for gene delivery and lineage-specific differentiation in human embryonic stem cells. Cell Stem Cell. 5: 332-42. PMID 19733544 DOI: 10.1016/j.stem.2009.07.011  0.34
2009 Di Pasquale E, Brivanlou AH. Bone morphogenetic protein 15 (BMP15) acts as a BMP and Wnt inhibitor during early embryogenesis. The Journal of Biological Chemistry. 284: 26127-36. PMID 19553676 DOI: 10.1074/jbc.M109.036608  0.336
2009 Yan CY, Skourides P, Chang C, Brivanlou A. Samba, a Xenopus hnRNP expressed in neural and neural crest tissues. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 238: 204-9. PMID 19097051 DOI: 10.1002/Dvdy.21826  0.418
2009 Levine AJ, Levine ZJ, Brivanlou AH. GDF3 is a BMP inhibitor that can activate Nodal signaling only at very high doses. Developmental Biology. 325: 43-8. PMID 18823971 DOI: 10.1016/j.ydbio.2008.09.006  0.68
2009 Lacoste A, Berenshteyn F, Brivanlou AH. An Efficient and Reversible Transposable System for Gene Delivery and Lineage-Specific Differentiation in Human Embryonic Stem Cells (DOI:10.1016/j.stem.2009.07.011) Cell Stem Cell. 5: 568. DOI: 10.1016/j.stem.2009.10.013  0.351
2007 Dreesen O, Brivanlou AH. Signaling pathways in cancer and embryonic stem cells. Stem Cell Reviews. 3: 7-17. PMID 17873377 DOI: 10.1007/s12015-007-0004-8  0.4
2007 Levine AJ, Brivanlou AH. Proposal of a model of mammalian neural induction. Developmental Biology. 308: 247-56. PMID 17585896 DOI: 10.1016/j.ydbio.2007.05.036  0.706
2007 Noggle SA, Spagnoli FM, Brivanlou AH. In vivo Differentiation of Human Embryonic Stem Cells Human Embryonic Stem Cells: the Practical Handbook. 121-147. DOI: 10.1002/9780470511619.ch9  0.397
2006 Chang C, Brivanlou AH, Harland RM. Function of the two Xenopus smad4s in early frog development. The Journal of Biological Chemistry. 281: 30794-803. PMID 16908518 DOI: 10.1074/Jbc.M607054200  0.561
2006 Knockaert M, Sapkota G, Alarcón C, Massagué J, Brivanlou AH. Unique players in the BMP pathway: small C-terminal domain phosphatases dephosphorylate Smad1 to attenuate BMP signaling. Proceedings of the National Academy of Sciences of the United States of America. 103: 11940-5. PMID 16882717 DOI: 10.1073/Pnas.0605133103  0.302
2006 Sato N, Brivanlou AH. Microarray approach to identify the signaling network responsible for self-renewal of human embryonic stem cells. Methods in Molecular Biology (Clifton, N.J.). 331: 267-83. PMID 16881522 DOI: 10.1385/1-59745-046-4:267  0.376
2006 Sato N, Brivanlou AH. Manipulation of self-renewal in human embryonic stem cells through a novel pharmacological GSK-3 inhibitor. Methods in Molecular Biology (Clifton, N.J.). 331: 115-28. PMID 16881513 DOI: 10.1385/1-59745-046-4:115  0.409
2006 James D, Noggle SA, Swigut T, Brivanlou AH. Contribution of human embryonic stem cells to mouse blastocysts. Developmental Biology. 295: 90-102. PMID 16769046 DOI: 10.1016/j.ydbio.2006.03.026  0.397
2006 Levine AJ, Brivanlou AH. GDF3 at the crossroads of TGF-beta signaling. Cell Cycle (Georgetown, Tex.). 5: 1069-73. PMID 16721050  0.707
2006 Vonica A, Brivanlou AH. An obligatory caravanserai stop on the silk road to neural induction: inhibition of BMP/GDF signaling. Seminars in Cell & Developmental Biology. 17: 117-32. PMID 16516504 DOI: 10.1016/J.Semcdb.2005.11.013  0.328
2006 Levine AJ, Brivanlou AH. GDF3, a BMP inhibitor, regulates cell fate in stem cells and early embryos. Development (Cambridge, England). 133: 209-16. PMID 16339188 DOI: 10.1242/dev.02192  0.75
2005 Noggle SA, James D, Brivanlou AH. A molecular basis for human embryonic stem cell pluripotency. Stem Cell Reviews. 1: 111-8. PMID 17142845 DOI: 10.1385/SCR:1:2:111  0.443
2005 Wysocka J, Swigut T, Milne TA, Dou Y, Zhang X, Burlingame AL, Roeder RG, Brivanlou AH, Allis CD. WDR5 associates with histone H3 methylated at K4 and is essential for H3 K4 methylation and vertebrate development. Cell. 121: 859-72. PMID 15960974 DOI: 10.1016/J.Cell.2005.03.036  0.36
2005 Spagnoli FM, Brivanlou AH. A full menu for stem-cell research. Genome Biology. 6: 311. PMID 15774038 DOI: 10.1186/gb-2005-6-3-311  0.304
2004 Sato N, Meijer L, Skaltsounis L, Greengard P, Brivanlou AH. Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor. Nature Medicine. 10: 55-63. PMID 14702635 DOI: 10.1038/nm979  0.416
2003 Meijer L, Skaltsounis AL, Magiatis P, Polychronopoulos P, Knockaert M, Leost M, Ryan XP, Vonica CA, Brivanlou A, Dajani R, Crovace C, Tarricone C, Musacchio A, Roe SM, Pearl L, et al. GSK-3-selective inhibitors derived from Tyrian purple indirubins. Chemistry & Biology. 10: 1255-66. PMID 14700633 DOI: 10.1016/j.chembiol.2003.11.010  0.304
2003 Sato N, Sanjuan IM, Heke M, Uchida M, Naef F, Brivanlou AH. Molecular signature of human embryonic stem cells and its comparison with the mouse. Developmental Biology. 260: 404-13. PMID 12921741 DOI: 10.1016/S0012-1606(03)00256-2  0.416
2003 Brivanlou AH, Gage FH, Jaenisch R, Jessell T, Melton D, Rossant J. Stem cells. Setting standards for human embryonic stem cells. Science (New York, N.Y.). 300: 913-6. PMID 12738841 DOI: 10.1126/Science.1082940  0.599
2003 Chang C, Eggen BJ, Weinstein DC, Brivanlou AH. Regulation of nodal and BMP signaling by tomoregulin-1 (X7365) through novel mechanisms. Developmental Biology. 255: 1-11. PMID 12618130 DOI: 10.1016/S0012-1606(02)00075-1  0.353
2003 Levine AJ, Munoz-Sanjuan I, Bell E, North AJ, Brivanlou AH. Fluorescent labeling of endothelial cells allows in vivo, continuous characterization of the vascular development of Xenopus laevis. Developmental Biology. 254: 50-67. PMID 12606281 DOI: 10.1016/S0012-1606(02)00029-5  0.658
2003 Bell E, Muñoz-Sanjuán I, Altmann CR, Vonica A, Brivanlou AH. Cell fate specification and competence by Coco, a maternal BMP, TGFbeta and Wnt inhibitor. Development (Cambridge, England). 130: 1381-9. PMID 12588853 DOI: 10.1242/Dev.00344  0.383
2002 Muñoz-Sanjuán I, Bell E, Altmann CR, Vonica A, Brivanlou AH. Gene profiling during neural induction in Xenopus laevis: regulation of BMP signaling by post-transcriptional mechanisms and TAB3, a novel TAK1-binding protein. Development (Cambridge, England). 129: 5529-40. PMID 12403722 DOI: 10.1242/Dev.00097  0.354
2002 Altmann CR, Chang C, Muñoz-Sanjuán I, Bell E, Heke M, Rifkin DB, Brivanlou AH. The latent-TGFbeta-binding-protein-1 (LTBP-1) is expressed in the organizer and regulates nodal and activin signaling. Developmental Biology. 248: 118-27. PMID 12142025 DOI: 10.1006/Dbio.2002.0716  0.302
2002 Muñoz-Sanjuán I, Brivanlou AH. Neural induction, the default model and embryonic stem cells. Nature Reviews. Neuroscience. 3: 271-80. PMID 11967557 DOI: 10.1038/nrn786  0.395
2001 Zohn IE, Brivanlou AH. Expression cloning of Xenopus Os4, an evolutionarily conserved gene, which induces mesoderm and dorsal axis. Developmental Biology. 239: 118-31. PMID 11784023 DOI: 10.1006/dbio.2001.0420  0.361
2001 Chang C, Holtzman DA, Chau S, Chickering T, Woolf EA, Holmgren LM, Bodorova J, Gearing DP, Holmes WE, Brivanlou AH. Twisted gastrulation can function as a BMP antagonist. Nature. 410: 483-7. PMID 11260717 DOI: 10.1038/35068583  0.318
2001 Altmann CR, Brivanlou AH. Neural patterning in the vertebrate embryo. International Review of Cytology. 203: 447-82. PMID 11131523  0.307
1998 Casellas R, Brivanlou AH. Xenopus Smad7 inhibits both the activin and BMP pathways and acts as a neural inducer. Developmental Biology. 198: 1-12. PMID 9640328 DOI: 10.1016/S0012-1606(98)80025-0  0.328
1990 Condie BG, Brivanlou AH, Harland RM. Most of the homeobox-containing Xhox 36 transcripts in early Xenopus embryos cannot encode a homeodomain protein. Molecular and Cellular Biology. 10: 3376-85. PMID 1972542  0.667
1989 Brivanlou AH, Harland RM. Expression of an engrailed-related protein is induced in the anterior neural ectoderm of early Xenopus embryos. Development (Cambridge, England). 106: 611-7. PMID 2574664  0.507
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