Christoher Glembotski - Publications

Affiliations: 
Biology University of California, San Diego, La Jolla, CA 
Area:
General Biology, Cell Biology, Molecular Biology

86 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Marsh KG, Arrieta A, Thuerauf DJ, Blackwood EA, MacDonnell L, Glembotski CC. The peroxisomal enzyme, FAR1, is induced during ER stress in an ATF6-dependent manner in cardiac myocytes. American Journal of Physiology. Heart and Circulatory Physiology. PMID 33666503 DOI: 10.1152/ajpheart.00999.2020  0.535
2020 Blackwood EA, Bilal AS, Azizi K, Sarakki A, Glembotski CC. Simultaneous Isolation and Culture of Atrial Myocytes, Ventricular Myocytes, and Non-Myocytes from an Adult Mouse Heart. Journal of Visualized Experiments : Jove. PMID 32597844 DOI: 10.3791/61224  0.337
2020 Blackwood EA, Thuerauf DJ, Stastna M, Stephens H, Sand Z, Pentoney A, Azizi K, Jakobi T, Van Eyk JE, Katus HA, Glembotski CC, Doroudgar S. Proteomic analysis of the cardiac myocyte secretome reveals extracellular protective functions for the ER stress response. Journal of Molecular and Cellular Cardiology. PMID 32339566 DOI: 10.1016/J.Yjmcc.2020.04.012  0.694
2020 Arrieta A, Blackwood EA, Stauffer WT, Domingo MS, Bilal AS, Thuerauf DJ, Pentoney AN, Aivati C, Sarakki AV, Doroudgar S, Glembotski CC. Mesencephalic astrocyte-derived neurotrophic factor is an ER-resident chaperone that protects against reductive stress in the heart. The Journal of Biological Chemistry. PMID 32327487 DOI: 10.1074/Jbc.Ra120.013345  0.64
2020 Glembotski CC, Arrieta A, Blackwood EA, Stauffer WT. ATF6 as a Nodal Regulator of Proteostasis in the Heart. Frontiers in Physiology. 11: 267. PMID 32322217 DOI: 10.3389/Fphys.2020.00267  0.601
2020 Blackwood EA, Bilal AS, Stauffer WT, Arrieta A, Glembotski CC. Designing Novel Therapies to Mend Broken Hearts: ATF6 and Cardiac Proteostasis. Cells. 9. PMID 32138230 DOI: 10.3390/Cells9030602  0.546
2020 Stauffer WT, Blackwood EA, Azizi K, Kaufman RJ, Glembotski CC. The ER Unfolded Protein Response Effector, ATF6, Reduces Cardiac Fibrosis and Decreases Activation of Cardiac Fibroblasts. International Journal of Molecular Sciences. 21. PMID 32085622 DOI: 10.3390/Ijms21041373  0.484
2020 Stauffer WT, Arrieta A, Blackwood EA, Glembotski CC. Sledgehammer to Scalpel: Broad Challenges to the Heart and Other Tissues Yield Specific Cellular Responses via Transcriptional Regulation of the ER-Stress Master Regulator ATF6α. International Journal of Molecular Sciences. 21. PMID 32046286 DOI: 10.3390/Ijms21031134  0.528
2020 Blackwood E, Thuerauf D, MacDonnell L, Bilal AS, Glembotski CC. Abstract 15063: The Atf6-inducible Selenoprotein, Vimp, Regulates Proteostasis and Pressure Overload-induced Heart Failure Circulation. 142. DOI: 10.1161/circ.142.suppl_3.15063  0.491
2019 Arrieta A, Blackwood EA, Stauffer WT, Glembotski CC. Integrating ER and Mitochondrial Proteostasis in the Healthy and Diseased Heart. Frontiers in Cardiovascular Medicine. 6: 193. PMID 32010709 DOI: 10.3389/Fcvm.2019.00193  0.482
2019 Glembotski CC, Rosarda JD, Wiseman RL. Proteostasis and Beyond: ATF6 in Ischemic Disease. Trends in Molecular Medicine. PMID 31078432 DOI: 10.1016/J.Molmed.2019.03.005  0.394
2019 Blackwood EA, Azizi K, Thuerauf DJ, Paxman RJ, Plate L, Kelly JW, Wiseman RL, Glembotski CC. Pharmacologic ATF6 activation confers global protection in widespread disease models by reprograming cellular proteostasis. Nature Communications. 10: 187. PMID 30643122 DOI: 10.1016/J.Yjmcc.2018.07.047  0.44
2019 Blackwood EA, Hofmann C, Santo Domingo M, Bilal AS, Sarakki A, Stauffer W, Arrieta A, Thuerauf DJ, Kolkhorst FW, Müller OJ, Jakobi T, Dieterich C, Katus HA, Doroudgar S, Glembotski CC. ATF6 Regulates Cardiac Hypertrophy by Transcriptional Induction of the mTORC1 Activator, Rheb. Circulation Research. 124: 79-93. PMID 30582446 DOI: 10.1161/Circresaha.118.313854  0.57
2019 Stauffer WT, Blackwood EA, Azizi K, Stephens HN, Doroudgar S, Glembotski CC. Abstract 260: The ER Unfolded Protein Response Effector, ATF6, Reduces Fibrosis and Moderates Activation of Cardiac Fibroblasts Circulation Research. 125. DOI: 10.1161/Res.125.Suppl_1.260  0.496
2018 Paxman R, Plate L, Blackwood EA, Glembotski C, Powers ET, Wiseman RL, Kelly JW. Pharmacologic ATF6 activating compounds are metabolically activated to selectively modify endoplasmic reticulum proteins. Elife. 7. PMID 30084354 DOI: 10.7554/Elife.37168  0.395
2018 Stauffer WT, Doroudgar S, Stephens HN, Blackwood EA, Glembotski CC. Abstract 479: The ER Unfolded Protein Response Effector, ATF6, Promotes Proliferation and Maintains Pluripotency in Cardiac Stem Cells Circulation Research. 123. DOI: 10.1161/Res.123.Suppl_1.479  0.431
2018 Arrieta A, Blackwood EA, Aivati C, Stauffer WT, Santo Domingo M, Bilal AS, Sarakki AV, Thuerauf DJ, Doroudgar S, Glembotski CC. Abstract 352: Manf, a Structurally Unique Redox-sensitive Chaperone, Restores Er-protein Folding in the Ischemic Heart Circulation Research. 123. DOI: 10.1161/Res.123.Suppl_1.352  0.551
2017 Arrieta A, Blackwood EA, Glembotski CC. ER Protein Quality Control and the Unfolded Protein Response in the Heart. Current Topics in Microbiology and Immunology. PMID 29026925 DOI: 10.1007/82_2017_54  0.507
2017 Sacchi V, Wang BJ, Kubli D, Martinez AS, Jin JK, Alvarez R, Hariharan N, Glembotski C, Uchida T, Malter JS, Yang Y, Gross P, Zhang C, Houser S, Rota M, et al. Peptidyl-Prolyl Isomerase 1 Regulates Ca(2+) Handling by Modulating Sarco(Endo)Plasmic Reticulum Calcium ATPase and Na(2+)/Ca(2+) Exchanger 1 Protein Levels and Function. Journal of the American Heart Association. 6. PMID 29018025 DOI: 10.1161/Jaha.117.006837  0.38
2017 Gray CB, Suetomi T, Xiang S, Blackwood EA, Glembotski CC, Miyamoto S, Daan Westenbrink B, Brown JH. CaMKIIδ subtypes differentially regulate infarct formation following ex vivo myocardial ischemia/reperfusion through NF-κB and TNF-α. Journal of Molecular and Cellular Cardiology. PMID 28077321 DOI: 10.1016/J.Yjmcc.2017.01.002  0.341
2017 Arrieta A, Blackwood E, Stauffer WT, Domingo MS, Pentoney AN, Thuerauf DJ, Doroudgar S, Glembotski CC. MANF, a structurally unique redox-sensitive chaperone, restores ER-protein folding in the ischemic heart Journal of Molecular and Cellular Cardiology. 112: 165. DOI: 10.1016/J.Yjmcc.2017.07.102  0.492
2016 Jin JK, Blackwood EA, Azizi KM, Thuerauf DJ, Fahem AG, Hofmann C, Kaufman RJ, Doroudgar S, Glembotski CC. ATF6 Decreases Myocardial Ischemia/Reperfusion Damage and Links ER Stress and Oxidative Stress Signaling Pathways in the Heart. Circulation Research. PMID 27932512 DOI: 10.1161/Circresaha.116.310266  0.547
2016 Reynolds JO, Quick AP, Wang Q, Beavers DL, Philippen LE, Showell J, Barreto-Torres G, Thuerauf DJ, Doroudgar S, Glembotski CC, Wehrens XH. Junctophilin-2 gene therapy rescues heart failure by normalizing RyR2-mediated Ca(2+) release. International Journal of Cardiology. 225: 371-380. PMID 27760414 DOI: 10.1016/J.Ijcard.2016.10.021  0.33
2016 Doroudgar S, Quijada P, Konstandin M, Ilves K, Broughton K, Khalafalla FG, Casillas A, Nguyen K, Gude N, Toko H, Ornelas L, Thuerauf DJ, Glembotski CC, Sussman MA, Völkers M. S100A4 protects the myocardium against ischemic stress. Journal of Molecular and Cellular Cardiology. PMID 27721024 DOI: 10.1016/J.Yjmcc.2016.10.001  0.386
2016 Yu Z, Sheng H, Liu S, Zhao S, Glembotski CC, Warner DS, Paschen W, Yang W. Activation of the ATF6 branch of the unfolded protein response in neurons improves stroke outcome. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. PMID 27217380 DOI: 10.1177/0271678X16650218  0.366
2015 Glembotski CC. Breaking down the COP9 Signalsome in the heart: how inactivating a protein ubiquitin ligase increases protein ubiquitylation and protects the heart. Circulation Research. 117: 914-6. PMID 26541679 DOI: 10.1161/Circresaha.115.307644  0.445
2015 Doroudgar S, Völkers M, Thuerauf DJ, Khan M, Mohsin S, Respress JL, Wang W, Gude N, Müller OJ, Wehrens XH, Sussman MA, Glembotski CC. Hrd1 and ER-Associated Protein Degradation, ERAD, Are Critical Elements of the Adaptive ER Stress Response in Cardiac Myocytes. Circulation Research. 117: 536-46. PMID 26137860 DOI: 10.1161/Circresaha.115.306993  0.583
2014 Glembotski CC. Finding the missing link between the unfolded protein response and O-GlcNAcylation in the heart. Circulation Research. 115: 546-8. PMID 25170091 DOI: 10.1161/Circresaha.114.304855  0.517
2014 Glembotski CC. Roles for ATF6 and the sarco/endoplasmic reticulum protein quality control system in the heart. Journal of Molecular and Cellular Cardiology. 71: 11-5. PMID 24140798 DOI: 10.1016/J.Yjmcc.2013.09.018  0.491
2013 Glembotski CC. Classic studies of cultured cardiac myocyte hypertrophy: interview with a transformer. Circulation Research. 113: 1112-6. PMID 24158575 DOI: 10.1161/Circresaha.113.302490  0.35
2013 Völkers M, Toko H, Doroudgar S, Din S, Quijada P, Joyo AY, Ornelas L, Joyo E, Thuerauf DJ, Konstandin MH, Gude N, Glembotski CC, Sussman MA. Pathological hypertrophy amelioration by PRAS40-mediated inhibition of mTORC1. Proceedings of the National Academy of Sciences of the United States of America. 110: 12661-6. PMID 23842089 DOI: 10.1073/Pnas.1301455110  0.31
2013 Toko H, Konstandin MH, Doroudgar S, Ormachea L, Joyo E, Joyo AY, Din S, Gude NA, Collins B, Völkers M, Thuerauf DJ, Glembotski CC, Chen CH, Lu KP, Müller OJ, et al. Regulation of cardiac hypertrophic signaling by prolyl isomerase Pin1. Circulation Research. 112: 1244-52. PMID 23487407 DOI: 10.1161/Circresaha.113.301084  0.333
2013 Doroudgar S, Glembotski CC. ATF6 [corrected] and thrombospondin 4: the dynamic duo of the adaptive endoplasmic reticulum stress response. Circulation Research. 112: 9-12. PMID 23287452 DOI: 10.1161/Circresaha.112.280560  0.589
2013 Doroudgar S, Glembotski CC. New concepts of endoplasmic reticulum function in the heart: programmed to conserve. Journal of Molecular and Cellular Cardiology. 55: 85-91. PMID 23085588 DOI: 10.1016/J.Yjmcc.2012.10.006  0.549
2012 Glembotski CC. Roles for the sarco-/endoplasmic reticulum in cardiac myocyte contraction, protein synthesis, and protein quality control. Physiology (Bethesda, Md.). 27: 343-50. PMID 23223628 DOI: 10.1152/Physiol.00034.2012  0.503
2012 Glembotski CC. Clarifying the cardiac proteasome paradox: protein quality control. Circulation Research. 111: 509-12. PMID 22904038 DOI: 10.1161/Circresaha.112.275917  0.436
2012 Eletto D, Maganty A, Eletto D, Dersh D, Makarewich C, Biswas C, Paton JC, Paton AW, Doroudgar S, Glembotski CC, Argon Y. Limitation of individual folding resources in the ER leads to outcomes distinct from the unfolded protein response. Journal of Cell Science. 125: 4865-75. PMID 22854046 DOI: 10.1242/jcs.108928  0.476
2012 Glembotski CC, Thuerauf DJ, Huang C, Vekich JA, Gottlieb RA, Doroudgar S. Mesencephalic astrocyte-derived neurotrophic factor protects the heart from ischemic damage and is selectively secreted upon sarco/endoplasmic reticulum calcium depletion. The Journal of Biological Chemistry. 287: 25893-904. PMID 22637475 DOI: 10.1074/Jbc.M112.356345  0.498
2012 Vekich JA, Belmont PJ, Thuerauf DJ, Glembotski CC. Protein disulfide isomerase-associated 6 is an ATF6-inducible ER stress response protein that protects cardiac myocytes from ischemia/reperfusion-mediated cell death. Journal of Molecular and Cellular Cardiology. 53: 259-67. PMID 22609432 DOI: 10.1016/J.Yjmcc.2012.05.005  0.501
2012 Belmont PJ, Chen WJ, Thuerauf DJ, Glembotski CC. Regulation of microRNA expression in the heart by the ATF6 branch of the ER stress response. Journal of Molecular and Cellular Cardiology. 52: 1176-82. PMID 22326432 DOI: 10.1016/J.Yjmcc.2012.01.017  0.357
2011 Doroudgar S, Glembotski CC. The cardiokine story unfolds: ischemic stress-induced protein secretion in the heart. Trends in Molecular Medicine. 17: 207-14. PMID 21277256 DOI: 10.1016/J.Molmed.2010.12.003  0.6
2011 Glembotski CC. Functions for the cardiomyokine, MANF, in cardioprotection, hypertrophy and heart failure. Journal of Molecular and Cellular Cardiology. 51: 512-7. PMID 20970425 DOI: 10.1016/J.Yjmcc.2010.10.008  0.484
2010 Miyamoto S, Purcell NH, Smith JM, Gao T, Whittaker R, Huang K, Castillo R, Glembotski CC, Sussman MA, Newton AC, Brown JH. PHLPP-1 negatively regulates Akt activity and survival in the heart. Circulation Research. 107: 476-84. PMID 20576936 DOI: 10.1161/Circresaha.109.215020  0.322
2010 Belmont PJ, Chen WJ, San Pedro MN, Thuerauf DJ, Lowe NG, Gude N, Hilton B, Wolkowicz R, Sussman MA, Glembotski CC. Roles for endoplasmic reticulum-associated degradation and the novel endoplasmic reticulum stress response gene derlin-3 in the ischemic heart Circulation Research. 106: 307-316. PMID 19940266 DOI: 10.1161/Circresaha.109.203901  0.601
2009 Doroudgar S, Thuerauf DJ, Marcinko MC, Belmont PJ, Glembotski CC. Ischemia activates the ATF6 branch of the endoplasmic reticulum stress response. The Journal of Biological Chemistry. 284: 29735-45. PMID 19622751 DOI: 10.1074/Jbc.M109.018036  0.548
2009 Whittaker R, Glassy MS, Gude N, Sussman MA, Gottlieb RA, Glembotski CC. Kinetics of the translocation and phosphorylation of alphaB-crystallin in mouse heart mitochondria during ex vivo ischemia. American Journal of Physiology. Heart and Circulatory Physiology. 296: H1633-42. PMID 19252088 DOI: 10.1152/Ajpheart.01227.2008  0.312
2008 Tadimalla A, Belmont PJ, Thuerauf DJ, Glassy MS, Martindale JJ, Gude N, Sussman MA, Glembotski CC. Mesencephalic astrocyte-derived neurotrophic factor is an ischemia-inducible secreted endoplasmic reticulum stress response protein in the heart. Circulation Research. 103: 1249-58. PMID 18927462 DOI: 10.1161/Circresaha.108.180679  0.678
2008 Belmont PJ, Tadimalla A, Chen WJ, Martindale JJ, Thuerauf DJ, Marcinko M, Gude N, Sussman MA, Glembotski CC. Coordination of growth and endoplasmic reticulum stress signaling by regulator of calcineurin 1 (RCAN1), a novel ATF6-inducible gene. The Journal of Biological Chemistry. 283: 14012-21. PMID 18319259 DOI: 10.1074/Jbc.M709776200  0.547
2008 Glembotski CC. The role of the unfolded protein response in the heart. Journal of Molecular and Cellular Cardiology. 44: 453-9. PMID 18054039 DOI: 10.1016/J.Yjmcc.2007.10.017  0.579
2008 Jin JK, Whittaker R, Glassy MS, Barlow SB, Gottlieb RA, Glembotski CC. Localization of phosphorylated alphaB-crystallin to heart mitochondria during ischemia-reperfusion. American Journal of Physiology. Heart and Circulatory Physiology. 294: H337-44. PMID 17993600 DOI: 10.1152/Ajpheart.00881.2007  0.37
2007 Muraski JA, Rota M, Misao Y, Fransioli J, Cottage C, Gude N, Esposito G, Delucchi F, Arcarese M, Alvarez R, Siddiqi S, Emmanuel GN, Wu W, Fischer K, Martindale JJ, ... Glembotski CC, et al. Pim-1 regulates cardiomyocyte survival downstream of Akt Nature Medicine. 13: 1467-1475. PMID 18037896 DOI: 10.1038/Nm1671  0.343
2007 Glembotski CC. Endoplasmic reticulum stress in the heart. Circulation Research. 101: 975-84. PMID 17991891 DOI: 10.1161/Circresaha.107.161273  0.449
2007 Glembotski CC. Getting a G--RRP on regulated exocytosis in the heart. The Journal of Cell Biology. 179: 371-3. PMID 17967951 DOI: 10.1083/Jcb.200710021  0.34
2006 Thuerauf DJ, Marcinko M, Gude N, Rubio M, Sussman MA, Glembotski CC. Activation of the unfolded protein response in infarcted mouse heart and hypoxic cultured cardiac myocytes. Circulation Research. 99: 275-82. PMID 16794188 DOI: 10.1161/01.Res.0000233317.70421.03  0.651
2006 Wall JA, Wei J, Ly M, Belmont P, Martindale JJ, Tran D, Sun J, Chen WJ, Yu W, Oeller P, Briggs S, Gustafsson AB, Sayen MR, Gottlieb RA, Glembotski CC. Alterations in oxidative phosphorylation complex proteins in the hearts of transgenic mice that overexpress the p38 MAP kinase activator, MAP kinase kinase 6. American Journal of Physiology. Heart and Circulatory Physiology. 291: H2462-72. PMID 16766635 DOI: 10.1152/Ajpheart.01311.2005  0.335
2006 Martindale JJ, Fernandez R, Thuerauf D, Whittaker R, Gude N, Sussman MA, Glembotski CC. Endoplasmic reticulum stress gene induction and protection from ischemia/reperfusion injury in the hearts of transgenic mice with a tamoxifen-regulated form of ATF6. Circulation Research. 98: 1186-93. PMID 16601230 DOI: 10.1161/01.Res.0000220643.65941.8D  0.564
2005 Martindale JJ, Wall JA, Martinez-Longoria DM, Aryal P, Rockman HA, Guo Y, Bolli R, Glembotski CC. Overexpression of mitogen-activated protein kinase kinase 6 in the heart improves functional recovery from ischemia in vitro and protects against myocardial infarction in vivo. The Journal of Biological Chemistry. 280: 669-76. PMID 15492008 DOI: 10.1074/Jbc.M406690200  0.438
2004 Thuerauf DJ, Morrison L, Glembotski CC. Opposing roles for ATF6alpha and ATF6beta in endoplasmic reticulum stress response gene induction. The Journal of Biological Chemistry. 279: 21078-84. PMID 14973138 DOI: 10.1074/Jbc.M400713200  0.395
2004 Morrison LE, Whittaker RJ, Klepper RE, Wawrousek EF, Glembotski CC. Roles for alphaB-crystallin and HSPB2 in protecting the myocardium from ischemia-reperfusion-induced damage in a KO mouse model. American Journal of Physiology. Heart and Circulatory Physiology. 286: H847-55. PMID 14592939 DOI: 10.1152/Ajpheart.00715.2003  0.407
2003 Andrews C, Ho PD, Dillmann WH, Glembotski CC, McDonough PM. The MKK6-p38 MAPK pathway prolongs the cardiac contractile calcium transient, downregulates SERCA2, and activates NF-AT. Cardiovascular Research. 59: 46-56. PMID 12829175 DOI: 10.1016/S0008-6363(03)00329-8  0.431
2003 Degousee N, Martindale J, Stefanski E, Cieslak M, Lindsay TF, Fish JE, Marsden PA, Thuerauf DJ, Glembotski CC, Rubin BB. MAP kinase kinase 6-p38 MAP kinase signaling cascade regulates cyclooxygenase-2 expression in cardiac myocytes in vitro and in vivo. Circulation Research. 92: 757-64. PMID 12649265 DOI: 10.1161/01.Res.0000067929.01404.03  0.316
2003 O'Brien NW, Gellings NM, Guo M, Barlow SB, Glembotski CC, Sabbadini RA. Factor associated with neutral sphingomyelinase activation and its role in cardiac cell death. Circulation Research. 92: 589-91. PMID 12637370 DOI: 10.1161/01.Res.0000066290.29715.67  0.393
2003 Morrison LE, Hoover HE, Thuerauf DJ, Glembotski CC. Mimicking phosphorylation of alphaB-crystallin on serine-59 is necessary and sufficient to provide maximal protection of cardiac myocytes from apoptosis. Circulation Research. 92: 203-11. PMID 12574148 DOI: 10.1161/01.Res.0000052989.83995.A5  0.459
2003 Cavalli AL, O'Brien NW, Barlow SB, Betto R, Glembotski CC, Palade PT, Sabbadini RA. Expression and functional characterization of SCaMPER: a sphingolipid-modulated calcium channel of cardiomyocytes. American Journal of Physiology. Cell Physiology. 284: C780-90. PMID 12421694 DOI: 10.1152/Ajpcell.00382.2002  0.394
2002 Thuerauf DJ, Morrison LE, Hoover H, Glembotski CC. Coordination of ATF6-mediated transcription and ATF6 degradation by a domain that is shared with the viral transcription factor, VP16. The Journal of Biological Chemistry. 277: 20734-9. PMID 11909875 DOI: 10.1074/Jbc.M201749200  0.399
2002 Post GR, Swiderski C, Waldrop BA, Salty L, Glembotski CC, Wolthuis RM, Mochizuki N. Guanine nucleotide exchange factor-like factor (Rlf) induces gene expression and potentiates alpha 1-adrenergic receptor-induced transcriptional responses in neonatal rat ventricular myocytes. The Journal of Biological Chemistry. 277: 15286-92. PMID 11847222 DOI: 10.1074/jbc.M111844200  0.348
2001 Thuerauf DJ, Hoover H, Meller J, Hernandez J, Su L, Andrews C, Dillmann WH, McDonough PM, Glembotski CC. Sarco/endoplasmic reticulum calcium ATPase-2 expression is regulated by ATF6 during the endoplasmic reticulum stress response: intracellular signaling of calcium stress in a cardiac myocyte model system. The Journal of Biological Chemistry. 276: 48309-17. PMID 11595740 DOI: 10.1074/Jbc.M107146200  0.589
2000 Nakajima N, Cavalli AL, Biral D, Glembotski CC, McDonough PM, Ho PD, Betto R, Sandoná D, Palade PT, Dettbarn CA, Klepper RE, Sabbadini RA. Expression and characterization of Edg-1 receptors in rat cardiomyocytes: calcium deregulation in response to sphingosine 1-phosphate. European Journal of Biochemistry / Febs. 267: 5679-86. PMID 10971577 DOI: 10.1046/J.1432-1327.2000.01656.X  0.437
2000 Hoover HE, Thuerauf DJ, Martindale JJ, Glembotski CC. alpha B-crystallin gene induction and phosphorylation by MKK6-activated p38. A potential role for alpha B-crystallin as a target of the p38 branch of the cardiac stress response. The Journal of Biological Chemistry. 275: 23825-33. PMID 10816593 DOI: 10.1074/Jbc.M003864200  0.377
1998 Thuerauf DJ, Arnold ND, Zechner D, Hanford DS, DeMartin KM, McDonough PM, Prywes R, Glembotski CC. p38 Mitogen-activated protein kinase mediates the transcriptional induction of the atrial natriuretic factor gene through a serum response element. A potential role for the transcription factor ATF6. The Journal of Biological Chemistry. 273: 20636-43. PMID 9685422 DOI: 10.1074/Jbc.273.32.20636  0.336
1998 Ross RS, Pham C, Shai SY, Goldhaber JI, Fenczik C, Glembotski CC, Ginsberg MH, Loftus JC. Beta1 integrins participate in the hypertrophic response of rat ventricular myocytes. Circulation Research. 82: 1160-72. PMID 9633916 DOI: 10.1161/01.Res.82.11.1160  0.336
1998 Zechner D, Craig R, Hanford DS, McDonough PM, Sabbadini RA, Glembotski CC. MKK6 activates myocardial cell NF-kappaB and inhibits apoptosis in a p38 mitogen-activated protein kinase-dependent manner. The Journal of Biological Chemistry. 273: 8232-9. PMID 9525929 DOI: 10.1074/Jbc.273.14.8232  0.353
1997 McDonough PM, Hanford DS, Sprenkle AB, Mellon NR, Glembotski CC. Collaborative roles for c-Jun N-terminal kinase, c-Jun, serum response factor, and Sp1 in calcium-regulated myocardial gene expression. The Journal of Biological Chemistry. 272: 24046-53. PMID 9295358 DOI: 10.1074/Jbc.272.38.24046  0.318
1997 Betto R, Teresi A, Turcato F, Salviati G, Sabbadini RA, Krown K, Glembotski CC, Kindman LA, Dettbarn C, Pereon Y, Yasui K, Palade PT. Sphingosylphosphocholine modulates the ryanodine receptor/calcium-release channel of cardiac sarcoplasmic reticulum membranes. The Biochemical Journal. 322: 327-33. PMID 9078280 DOI: 10.1042/bj3220327  0.343
1996 Krown KA, Page MT, Nguyen C, Zechner D, Gutierrez V, Comstock KL, Glembotski CC, Quintana PJ, Sabbadini RA. Tumor necrosis factor alpha-induced apoptosis in cardiac myocytes. Involvement of the sphingolipid signaling cascade in cardiac cell death. The Journal of Clinical Investigation. 98: 2854-65. PMID 8981934 DOI: 10.1172/Jci119114  0.379
1996 Post GR, Goldstein D, Thuerauf DJ, Glembotski CC, Brown JH. Dissociation of p44 and p42 mitogen-activated protein kinase activation from receptor-induced hypertrophy in neonatal rat ventricular myocytes. The Journal of Biological Chemistry. 271: 8452-7. PMID 8626545 DOI: 10.1074/Jbc.271.14.8452  0.34
1994 Thuerauf DJ, Hanford DS, Glembotski CC. Regulation of rat brain natriuretic peptide transcription. A potential role for GATA-related transcription factors in myocardial cell gene expression. The Journal of Biological Chemistry. 269: 17772-5. PMID 8027030  0.325
1994 McDonough PM, Stella SL, Glembotski CC. Involvement of cytoplasmic calcium and protein kinases in the regulation of atrial natriuretic factor secretion by contraction rate and endothelin. The Journal of Biological Chemistry. 269: 9466-72. PMID 7511588  0.406
1993 Irons CE, Sei CA, Glembotski CC. Regulated secretion of atrial natriuretic factor from cultured ventricular myocytes. The American Journal of Physiology. 264: H282-5. PMID 8430857 DOI: 10.1152/Ajpheart.1993.264.1.H282  0.301
1992 Sei CA, Hand GL, Murray SF, Glembotski CC. The cosecretional maturation of atrial natriuretic factor by primary atrial myocytes. Molecular Endocrinology (Baltimore, Md.). 6: 309-19. PMID 1533896 DOI: 10.1210/Mend.6.3.1533896  0.331
1992 McDonough PM, Glembotski CC. Induction of atrial natriuretic factor and myosin light chain-2 gene expression in cultured ventricular myocytes by electrical stimulation of contraction. The Journal of Biological Chemistry. 267: 11665-8. PMID 1376309  0.354
1991 Knowlton KU, Baracchini E, Ross RS, Harris AN, Henderson SA, Evans SM, Glembotski CC, Chien KR. Co-regulation of the atrial natriuretic factor and cardiac myosin light chain-2 genes during alpha-adrenergic stimulation of neonatal rat ventricular cells. Identification of cis sequences within an embryonic and a constitutive contractile protein gene which mediate inducible expression. The Journal of Biological Chemistry. 266: 7759-68. PMID 1850419  0.324
1991 Glembotski CC, Irons CE, Sprenkle AB, Sei CA. Studies of ANF processing and secretion using a primary cardiocyte culture model. Canadian Journal of Physiology and Pharmacology. 69: 1525-36. PMID 1838022 DOI: 10.1139/Y91-228  0.385
1991 Sei CA, Irons CE, Sprenkle AB, McDonough PM, Brown JH, Glembotski CC. The alpha-adrenergic stimulation of atrial natriuretic factor expression in cardiac myocytes requires calcium influx, protein kinase C, and calmodulin-regulated pathways. The Journal of Biological Chemistry. 266: 15910-6. PMID 1714900  0.386
1990 Shubeita HE, McDonough PM, Harris AN, Knowlton KU, Glembotski CC, Brown JH, Chien KR. Endothelin induction of inositol phospholipid hydrolysis, sarcomere assembly, and cardiac gene expression in ventricular myocytes. A paracrine mechanism for myocardial cell hypertrophy. The Journal of Biological Chemistry. 265: 20555-62. PMID 2173712  0.347
1990 Sei CA, Glembotski CC. Calcium dependence of phenylephrine-, endothelin-, and potassium chloride-stimulated atrial natriuretic factor secretion from long term primary neonatal rat atrial cardiocytes. The Journal of Biological Chemistry. 265: 7166-72. PMID 2158988  0.35
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