Year |
Citation |
Score |
2022 |
Janssen E, Peters Z, Alosaimi MF, Smith E, Milin E, Stafstrom K, Wallace JG, Platt CD, Chou J, El Ansari YS, Al Farsi T, Ameziane N, Al-Ali R, Calvo M, Rocha ME, ... ... Geha RS, et al. Immune dysregulation caused by homozygous mutations in CBLB. The Journal of Clinical Investigation. PMID 36006710 DOI: 10.1172/JCI154487 |
0.351 |
|
2021 |
Rais A, Mekki N, Fedhila F, Alosaimi MF, Ben Khaled M, Zameli A, Agrebi N, Sellami MK, Geha R, Ben-Mustapha I, Barbouche MR. Case Report: Mutation in a Patient Presenting With ALPS. Frontiers in Immunology. 12: 692107. PMID 34531853 DOI: 10.3389/fimmu.2021.692107 |
0.326 |
|
2020 |
Lorenzini T, Fliegauf M, Klammer N, Frede N, Proietti M, Bulashevska A, Camacho-Ordonez N, Varjosalo M, Kinnunen M, de Vries E, van der Meer JWM, Ameratunga R, Roifman CM, Schejter YD, Kobbe R, ... ... Geha R, et al. Characterization of the clinical and immunological phenotype and management of 157 individuals with 56 distinct heterozygous NFKB1 mutations. The Journal of Allergy and Clinical Immunology. PMID 32278790 DOI: 10.1016/J.Jaci.2019.11.051 |
0.338 |
|
2020 |
Kumari S, Mak M, Poh YC, Tohme M, Watson N, Melo M, Janssen E, Dustin M, Geha R, Irvine DJ. Cytoskeletal tension actively sustains the migratory T-cell synaptic contact. The Embo Journal. e102783. PMID 31894880 DOI: 10.15252/Embj.2019102783 |
0.307 |
|
2018 |
Meshaal SS, El Hawary RE, Abd Elaziz DS, Eldash A, Alkady R, Lotfy S, Mauracher AA, Opitz L, Pachlopnik Schmid J, van der Burg M, Chou J, Galal NM, Boutros JA, Geha R, Elmarsafy AM. Phenotypic Heterogeneity in RAG-deficient Patients from a Highly Consanguineous Population. Clinical and Experimental Immunology. PMID 30307608 DOI: 10.1111/Cei.13222 |
0.369 |
|
2018 |
Borzutzky A, Rauter I, Fried A, Rachid R, McDonald DR, Hammarstrom L, Grimbacher B, Abraham RS, Geha RS. Defective TLR9-driven STAT3 activation in B cells of patients with CVID. Clinical Immunology (Orlando, Fla.). PMID 30145329 DOI: 10.1016/j.clim.2018.08.008 |
0.314 |
|
2018 |
Schwab C, Gabrysch A, Olbrich P, Patiño V, Warnatz K, Wolff D, Hoshino A, Kobayashi M, Imai K, Takagi M, Dybedal I, Haddock JA, Sansom D, Lucena JM, Seidl M, ... ... Geha R, et al. Phenotype, penetrance, and treatment of 133 CTLA-4-insufficient individuals. The Journal of Allergy and Clinical Immunology. PMID 29729943 DOI: 10.1016/J.Jaci.2018.02.055 |
0.388 |
|
2017 |
Dobbs K, Tabellini G, Calzoni E, Patrizi O, Martinez P, Giliani SC, Moratto D, Al-Herz W, Cancrini C, Cowan M, Bleesing J, Booth C, Buchbinder D, Burns SO, Chatila TA, ... ... Geha R, et al. Corrigendum: Natural Killer Cells from Patients with Recombinase-Activating Gene and Non-Homologous End Joining Gene Defects Comprise a Higher Frequency of CD56(bright) NKG2A(+++) Cells, and Yet Display Increased Degranulation and Higher Perforin Content. Frontiers in Immunology. 8: 1244. PMID 29042861 DOI: 10.3389/Fimmu.2017.01244 |
0.307 |
|
2017 |
Massaad MJ, Cangemi B, Al-Herz W, LeFranc G, Freeman A, Baxi S, Keles S, Metin A, Dasouki M, Sobh A, Kanariou M, Al-Sukaiti N, Ozen A, Ochs H, Chatila TA, ... ... Geha R, et al. DOCK8 and STAT3 dependent inhibition of IgE isotype switching by TLR9 ligation in human B cells. Clinical Immunology (Orlando, Fla.). PMID 28882618 DOI: 10.1016/J.Clim.2017.08.020 |
0.346 |
|
2017 |
Marquardsen FA, Baldin F, Wunderer F, Al-Herz W, Mikhael R, Lefranc G, Baz Z, Rezaee F, Hanna R, Kfir-Erenfeld S, Stepensky P, Meyer B, Jauch A, Bigler MB, Burgener AV, ... ... Geha R, et al. Detection of Sp110 by Flow Cytometry and Application to Screening Patients for Veno-occlusive Disease with Immunodeficiency. Journal of Clinical Immunology. PMID 28825155 DOI: 10.1007/S10875-017-0431-5 |
0.307 |
|
2017 |
Platt CD, Fried AJ, Hoyos-Bachiloglu R, Naheed Usmani G, Schmidt B, Whangbo J, Chiarle R, Chou J, Geha RS. Combined immunodeficiency with EBV positive B cell lymphoma and epidermodysplasia verruciformis due to a novel homozygous mutation in RASGRP1. Clinical Immunology (Orlando, Fla.). PMID 28822832 DOI: 10.1016/J.Clim.2017.08.007 |
0.317 |
|
2017 |
Dobbs K, Tabellini G, Calzoni E, Patrizi O, Martinez P, Giliani SC, Moratto D, Al-Herz W, Cancrini C, Cowan M, Bleesing J, Booth C, Buchbinder D, Burns SO, Chatila TA, ... ... Geha R, et al. Natural Killer Cells from Patients with Recombinase-Activating Gene and Non-Homologous End Joining Gene Defects Comprise a Higher Frequency of CD56(bright) NKG2A(+++) Cells, and Yet Display Increased Degranulation and Higher Perforin Content. Frontiers in Immunology. 8: 798. PMID 28769923 DOI: 10.3389/Fimmu.2017.00798 |
0.407 |
|
2017 |
Petersheim D, Massaad MJ, Lee S, Scarselli A, Cancrini C, Moriya K, Sasahara Y, Lankester AC, Dorsey M, Di Giovanni D, Bezrodnik L, Ohnishi H, Nishikomori R, Tanita K, Kanegane H, ... ... Geha RS, et al. Severe disease and greater impairment of NF-κB activation in IκBa point mutants versus truncation mutants in autosomal dominant anhidrotic ectodermal dysplasia with immune deficiency. The Journal of Allergy and Clinical Immunology. PMID 28629746 DOI: 10.1016/J.Jaci.2017.05.030 |
0.304 |
|
2016 |
Massaad MJ, Zhou J, Tsuchimoto D, Chou J, Jabara H, Janssen E, Glauzy S, Olson BG, Morbach H, Ohsumi TK, Schmitz K, Kyriacos M, Kane J, Torisu K, Nakabeppu Y, ... ... Geha RS, et al. Deficiency of base excision repair enzyme NEIL3 drives increased predisposition to autoimmunity. The Journal of Clinical Investigation. PMID 27760045 DOI: 10.1172/Jci85647 |
0.337 |
|
2016 |
Jabara HH, Lee JJ, Janssen E, Ullas S, Liadaki K, Garibyan L, Benson H, Sannikova T, Bram R, Hammarstrom L, Cruz AC, Siegel R, Manis J, Malley R, Geha RS. Heterozygosity for TACI A144E causes haploinsufficiency and pneumococcal susceptibility in mice. The Journal of Allergy and Clinical Immunology. PMID 27609654 DOI: 10.1016/J.Jaci.2016.07.028 |
0.635 |
|
2015 |
Walter JE, Rosen LB, Csomos K, Rosenberg JM, Mathew D, Keszei M, Ujhazi B, Chen K, Lee YN, Tirosh I, Dobbs K, Al-Herz W, Cowan MJ, Puck J, Bleesing JJ, ... ... Geha R, et al. Broad-spectrum antibodies against self-antigens and cytokines in RAG deficiency. The Journal of Clinical Investigation. PMID 26457731 DOI: 10.1172/Jci80477 |
0.392 |
|
2015 |
Romberg N, Virdee M, Chamberlain N, Oe T, Schickel JN, Perkins T, Cantaert T, Rachid R, Rosengren S, Palazzo R, Geha R, Cunningham-Rundles C, Meffre E. TNF receptor superfamily member 13b (TNFRSF13B) hemizygosity reveals transmembrane activator and CAML interactor haploinsufficiency at later stages of B-cell development. The Journal of Allergy and Clinical Immunology. 136: 1315-25. PMID 26100089 DOI: 10.1016/J.Jaci.2015.05.012 |
0.455 |
|
2015 |
Mooster JL, Le Bras S, Massaad MJ, Jabara H, Yoon J, Galand C, Heesters BA, Burton OT, Mattoo H, Manis J, Geha RS. Defective lymphoid organogenesis underlies the immune deficiency caused by a heterozygous S32I mutation in IκBα. The Journal of Experimental Medicine. 212: 185-202. PMID 25601653 DOI: 10.1084/Jem.20140979 |
0.765 |
|
2015 |
Charbonnier LM, Janssen E, Chou J, Ohsumi TK, Keles S, Hsu JT, Massaad MJ, Garcia-Lloret M, Hanna-Wakim R, Dbaibo G, Alangari AA, Alsultan A, Al-Zahrani D, Geha RS, Chatila TA. Regulatory T-cell deficiency and immune dysregulation, polyendocrinopathy, enteropathy, X-linked-like disorder caused by loss-of-function mutations in LRBA. The Journal of Allergy and Clinical Immunology. 135: 217-27. PMID 25468195 DOI: 10.1016/J.Jaci.2014.10.019 |
0.344 |
|
2014 |
Turvey SE, Durandy A, Fischer A, Fung SY, Geha RS, Gewies A, Giese T, Greil J, Keller B, McKinnon ML, Neven B, Rozmus J, Ruland J, Snow AL, Stepensky P, et al. The CARD11-BCL10-MALT1 (CBM) signalosome complex: Stepping into the limelight of human primary immunodeficiency. The Journal of Allergy and Clinical Immunology. 134: 276-84. PMID 25087226 DOI: 10.1016/j.jaci.2014.06.015 |
0.306 |
|
2014 |
Al-Zahrani D, Raddadi A, Massaad M, Keles S, Jabara HH, Chatila TA, Geha R. Successful interferon-alpha 2b therapy for unremitting warts in a patient with DOCK8 deficiency. Clinical Immunology (Orlando, Fla.). 153: 104-8. PMID 24743019 DOI: 10.1016/J.Clim.2014.04.005 |
0.333 |
|
2014 |
Lee YN, Frugoni F, Dobbs K, Walter JE, Giliani S, Gennery AR, Al-Herz W, Haddad E, LeDeist F, Bleesing JH, Henderson LA, Pai SY, Nelson RP, El-Ghoneimy DH, El-Feky RA, ... ... Geha RS, et al. A systematic analysis of recombination activity and genotype-phenotype correlation in human recombination-activating gene 1 deficiency. The Journal of Allergy and Clinical Immunology. 133: 1099-108. PMID 24290284 DOI: 10.1016/J.Jaci.2013.10.007 |
0.333 |
|
2014 |
McDonald DR, Geha RS. Human Immunodeficiencies Resulting From Defective NF-κB Activation Stiehm's Immune Deficiencies. 665-686. DOI: 10.1016/B978-0-12-405546-9.00033-9 |
0.312 |
|
2013 |
Romberg N, Chamberlain N, Saadoun D, Gentile M, Kinnunen T, Ng YS, Virdee M, Menard L, Cantaert T, Morbach H, Rachid R, Martinez-Pomar N, Matamoros N, Geha R, Grimbacher B, et al. CVID-associated TACI mutations affect autoreactive B cell selection and activation. The Journal of Clinical Investigation. 123: 4283-93. PMID 24051380 DOI: 10.1172/Jci69854 |
0.471 |
|
2012 |
Oyoshi MK, He R, Li Y, Mondal S, Yoon J, Afshar R, Chen M, Lee DM, Luo HR, Luster AD, Cho JS, Miller LS, Larson A, Murphy GF, Geha RS. Leukotriene B4-driven neutrophil recruitment to the skin is essential for allergic skin inflammation. Immunity. 37: 747-58. PMID 23063331 DOI: 10.1016/j.immuni.2012.06.018 |
0.341 |
|
2012 |
Chou J, Hanna-Wakim R, Tirosh I, Kane J, Fraulino D, Lee YN, Ghanem S, Mahfouz I, Mégarbané A, Lefranc G, Inati A, Dbaibo G, Giliani S, Notarangelo LD, Geha RS, et al. A novel homozygous mutation in recombination activating gene 2 in 2 relatives with different clinical phenotypes: Omenn syndrome and hyper-IgM syndrome. The Journal of Allergy and Clinical Immunology. 130: 1414-6. PMID 22841008 DOI: 10.1016/J.Jaci.2012.06.012 |
0.365 |
|
2011 |
Ozcan E, Rauter I, Garibyan L, Dillon SR, Geha RS. Toll-like receptor 9, transmembrane activator and calcium-modulating cyclophilin ligand interactor, and CD40 synergize in causing B-cell activation. The Journal of Allergy and Clinical Immunology. 128: 601-9.e1-4. PMID 21741080 DOI: 10.1016/J.Jaci.2011.04.052 |
0.634 |
|
2010 |
Lee JJ, Jabara HH, Garibyan L, Rauter I, Sannikova T, Dillon SR, Bram R, Geha RS. The C104R mutant impairs the function of transmembrane activator and calcium modulator and cyclophilin ligand interactor (TACI) through haploinsufficiency. The Journal of Allergy and Clinical Immunology. 126: 1234-41.e2. PMID 20889194 DOI: 10.1016/J.Jaci.2010.08.017 |
0.631 |
|
2010 |
Mooster JL, Cancrini C, Simonetti A, Rossi P, Di Matteo G, Romiti ML, Di Cesare S, Notarangelo L, Geha RS, McDonald DR. Immune deficiency caused by impaired expression of nuclear factor-kappaB essential modifier (NEMO) because of a mutation in the 5' untranslated region of the NEMO gene. The Journal of Allergy and Clinical Immunology. 126: 127-32.e7. PMID 20542322 DOI: 10.1016/j.jaci.2010.04.026 |
0.751 |
|
2010 |
Lee J, Jabara H, Garibyan L, Rauter I, Sannikova T, Dillon S, Bram R, Geha R. The Murine Equivalent of the Heterozygous C104R TACI Mutation Impairs B Cell Function via Haploinsufficiency Journal of Allergy and Clinical Immunology. 125: AB56. DOI: 10.1016/J.Jaci.2009.12.944 |
0.648 |
|
2010 |
Romberg N, Saadoun D, Rachid R, Geha R, Grimbacher B, Cunningham-Rundles C, Meffre E. Transmembrane Activator and Calcium-modulator and Cyclophilin Ligand Interactor (TACI) Expression is Essential for Human B-cell Tolerance Journal of Allergy and Clinical Immunology. 125: AB125. DOI: 10.1016/J.Jaci.2009.12.495 |
0.343 |
|
2010 |
McDonald D, Goldman F, Gomez O, Issekutz A, Kumararatne D, Geha R. Impaired T Cell Receptor Activation in IRAK-4-Deficient Patients Clinical Immunology. 135: S102. DOI: 10.1016/J.Clim.2010.03.306 |
0.357 |
|
2009 |
Lee JJ, Rauter I, Garibyan L, Ozcan E, Sannikova T, Dillon SR, Cruz AC, Siegel RM, Bram R, Jabara H, Geha RS. The murine equivalent of the A181E TACI mutation associated with common variable immunodeficiency severely impairs B-cell function. Blood. 114: 2254-62. PMID 19605846 DOI: 10.1182/Blood-2008-11-189720 |
0.649 |
|
2009 |
Ozcan E, Garibyan L, Lee JJ, Bram RJ, Lam KP, Geha RS. Transmembrane activator, calcium modulator, and cyclophilin ligand interactor drives plasma cell differentiation in LPS-activated B cells. The Journal of Allergy and Clinical Immunology. 123: 1277-86.e5. PMID 19427685 DOI: 10.1016/J.Jaci.2009.03.019 |
0.632 |
|
2009 |
Jin H, Kumar L, Mathias C, Zurakowski D, Oettgen H, Gorelik L, Geha R. Toll-like receptor 2 is important for the T(H)1 response to cutaneous sensitization. The Journal of Allergy and Clinical Immunology. 123: 875-82.e1. PMID 19348925 DOI: 10.1016/J.Jaci.2009.02.007 |
0.367 |
|
2009 |
Ramesh N, Geha R. Recent advances in the biology of WASP and WIP. Immunologic Research. 44: 99-111. PMID 19018480 DOI: 10.1007/S12026-008-8086-1 |
0.321 |
|
2009 |
Ozcan E, Garibyan L, Lee J, Geha R. TACI Drives Plasma Cell Differentiation in LPS Activated B Cells Journal of Allergy and Clinical Immunology. 123: S94-S94. DOI: 10.1016/J.Jaci.2008.12.335 |
0.61 |
|
2008 |
Lee JJ, Ozcan E, Rauter I, Geha RS. Transmembrane activator and calcium-modulator and cyclophilin ligand interactor mutations in common variable immunodeficiency. Current Opinion in Allergy and Clinical Immunology. 8: 520-6. PMID 18978466 DOI: 10.1097/ACI.0b013e3283141200 |
0.33 |
|
2008 |
He R, Oyoshi MK, Garibyan L, Kumar L, Ziegler SF, Geha RS. TSLP acts on infiltrating effector T cells to drive allergic skin inflammation. Proceedings of the National Academy of Sciences of the United States of America. 105: 11875-80. PMID 18711124 DOI: 10.1073/Pnas.0801532105 |
0.629 |
|
2008 |
Castigli E, Geha RS. TACI, isotype switching, CVID and IgAD. Immunologic Research. 38: 102-11. PMID 17917015 DOI: 10.1007/s12026-007-8000-2 |
0.318 |
|
2008 |
PAI S, LEVY O, JABARA H, GLICKMAN J, SACHS J, NURKO S, ORANGE J, GEHA R. Successful Correction of Immune Defects in a Patient with NEMO Mutation by Allogeneic Transplantation Uncovers Intrinsic Epithelial Basis for Colitis Journal of Allergy and Clinical Immunology. 121: S169-S169. DOI: 10.1016/J.Jaci.2007.12.621 |
0.362 |
|
2008 |
LEE J, GARIBYAN L, BRAM R, GEHA R. Murine Model of the Human TACI Mutation A181E Journal of Allergy and Clinical Immunology. 121: S144-S144. DOI: 10.1016/J.Jaci.2007.12.1111 |
0.631 |
|
2007 |
McDonald DR, Mooster JL, Reddy M, Bawle E, Secord E, Geha RS. Heterozygous N-terminal deletion of IkappaBalpha results in functional nuclear factor kappaB haploinsufficiency, ectodermal dysplasia, and immune deficiency. The Journal of Allergy and Clinical Immunology. 120: 900-7. PMID 17931563 DOI: 10.1016/J.Jaci.2007.08.035 |
0.748 |
|
2007 |
Castigli E, Wilson SA, Elkhal A, Ozcan E, Garibyan L, Geha RS. Transmembrane activator and calcium modulator and cyclophilin ligand interactor enhances CD40-driven plasma cell differentiation. The Journal of Allergy and Clinical Immunology. 120: 885-91. PMID 17689597 DOI: 10.1016/J.Jaci.2007.06.012 |
0.644 |
|
2007 |
Garibyan L, Lobito AA, Siegel RM, Call ME, Wucherpfennig KW, Geha RS. Dominant-negative effect of the heterozygous C104R TACI mutation in common variable immunodeficiency (CVID). The Journal of Clinical Investigation. 117: 1550-7. PMID 17492055 DOI: 10.1172/Jci31023 |
0.631 |
|
2007 |
Castigli E, Wilson S, Garibyan L, Rachid R, Bonilla F, Schneider L, Morra M, Curran J, Geha R. Reexamining the role of TACI coding variants in common variable immunodeficiency and selective IgA deficiency. Nature Genetics. 39: 430-1. PMID 17392798 DOI: 10.1038/Ng0407-430 |
0.607 |
|
2006 |
Castigli E, Geha RS. Molecular basis of common variable immunodeficiency. The Journal of Allergy and Clinical Immunology. 117: 740-6; quiz 747. PMID 16630927 DOI: 10.1016/j.jaci.2006.01.038 |
0.331 |
|
2006 |
McDonald DR, Janssen R, Geha R. Lessons learned from molecular defects in nuclear factor kappaB dependent signaling. Microbes and Infection / Institut Pasteur. 8: 1151-6. PMID 16517203 DOI: 10.1016/J.Micinf.2005.10.030 |
0.326 |
|
2005 |
Castigli E, Wilson SA, Garibyan L, Rachid R, Bonilla F, Schneider L, Geha RS. TACI is mutant in common variable immunodeficiency and IgA deficiency. Nature Genetics. 37: 829-34. PMID 16007086 DOI: 10.1038/Ng1601 |
0.659 |
|
2003 |
Winkelstein JA, Marino MC, Ochs H, Fuleihan R, Scholl PR, Geha R, Stiehm ER, Conley ME. The X-Linked Hyper-IgM Syndrome: Clinical and Immunologic Features of 79 Patients Medicine. 82: 373-384. PMID 14663287 DOI: 10.1097/01.Md.0000100046.06009.B0 |
0.303 |
|
2003 |
Bryce PJ, Geha R, Oettgen HC. Desloratadine inhibits allergen-induced airway inflammation and bronchial hyperresponsiveness and alters T-cell responses in murine models of asthma. The Journal of Allergy and Clinical Immunology. 112: 149-58. PMID 12847492 DOI: 10.1067/Mai.2003.1616 |
0.315 |
|
2003 |
Chapel H, Geha R, Rosen F. Primary immunodeficiency diseases: an update. Clinical and Experimental Immunology. 132: 9-15. PMID 12653830 DOI: 10.1046/J.1365-2249.2003.02110.X |
0.35 |
|
2002 |
Orange JS, Brodeur SR, Jain A, Bonilla FA, Schneider LC, Kretschmer R, Nurko S, Rasmussen WL, Köhler JR, Gellis SE, Ferguson BM, Strominger JL, Zonana J, Ramesh N, Ballas ZK, ... Geha RS, et al. Deficient natural killer cell cytotoxicity in patients with IKK-gamma/NEMO mutations. The Journal of Clinical Investigation. 109: 1501-9. PMID 12045264 DOI: 10.1172/Jci14858 |
0.359 |
|
1998 |
Sayos J, Wu C, Morra M, Wang N, Zhang X, Allen D, van Schaik S, Notarangelo L, Geha R, Roncarolo MG, Oettgen H, De Vries JE, Aversa G, Terhorst C. The X-linked lymphoproliferative-disease gene product SAP regulates signals induced through the co-receptor SLAM. Nature. 395: 462-9. PMID 9774102 DOI: 10.1038/26683 |
0.4 |
|
1997 |
Khan WN, Nilsson A, Mizoguchi E, Castigli E, Forsell J, Bhan AK, Geha R, Sideras P, Alt FW. Impaired B cell maturation in mice lacking Bruton's tyrosine kinase (Btk) and CD40. International Immunology. 9: 395-405. PMID 9088978 DOI: 10.1093/Intimm/9.3.395 |
0.403 |
|
1996 |
Jawahar S, Moody C, Chan M, Finberg R, Geha R, Chatila T. Natural Killer (NK) cell deficiency associated with an epitope-deficient Fc receptor type IIIA (CD16-II). Clinical and Experimental Immunology. 103: 408-13. PMID 8608639 DOI: 10.1111/J.1365-2249.1996.Tb08295.X |
0.349 |
|
1995 |
Ramesh N, Fuleihan R, Swinton P, Rosen FS, Geha R. A point mutation in exon 2 of the CD40 ligand gene causes the simultaneous expression of two defective mRNA species in X-linked hyperimmunoglobulinemia M Human Molecular Genetics. 4: 759-761. PMID 7543320 DOI: 10.1093/Hmg/4.4.759 |
0.322 |
|
1993 |
Ramesh N, Ramesh V, Gusella JF, Geha R. Chromosomal localization of the gene for human B-cell antigen CD40. Somatic Cell and Molecular Genetics. 19: 295-8. PMID 7687385 DOI: 10.1007/Bf01233077 |
0.327 |
|
1989 |
Schwartz D, Wong RCK, Chatila T, Arnaout A, Miller R, Geha R. Proliferation of highly purified T cells in response to signaling via surface receptors requires cell-cell contact. Journal of Clinical Immunology. 9: 151-158. PMID 2654172 DOI: 10.1007/Bf00916943 |
0.339 |
|
1989 |
Mourad W, Scholl P, Diaz A, Geha R, Chatila T. The staphylococcal toxic shock syndrome toxin 1 triggers b cell proliferation and differentiation via major histocompatibility complex-unrestricted cognate T/B cell interaction Journal of Experimental Medicine. 170: 2011-2022. PMID 2584933 DOI: 10.1084/Jem.170.6.2011 |
0.37 |
|
1989 |
Vercelli D, Helm B, Marsh P, Padlan E, Geha RS, Gould H. The B-cell binding site on human immunoglobulin E. Nature. 338: 649-51. PMID 2468089 DOI: 10.1038/338649A0 |
0.316 |
|
1982 |
Reinherz EL, Geha R, Rappeport JM, Wilson M, Penta AC, Hussey RE, Fitzgerald KA, Daley JF, Levine H, Rosen FS, Schlossman SF. Reconstitution after transplantation with T-lymphocyte-depleted HLA haplotype-mismatched bone marrow for severe combined immunodeficiency. Proceedings of the National Academy of Sciences of the United States of America. 79: 6047-6051. PMID 6764536 DOI: 10.1073/Pnas.79.19.6047 |
0.333 |
|
1981 |
Reinherz EL, Geha R, Wohl ME, Morimoto C, Rosen FS, Schlossman SF. Immunodeficiency associated with loss of T4+ inducer T-cell function. The New England Journal of Medicine. 304: 811-6. PMID 6451805 DOI: 10.1056/Nejm198104023041403 |
0.355 |
|
1977 |
Geha RS, Mudawwar F, Schneeberger E. The specificity of T-cell helper factor in man. The Journal of Experimental Medicine. 145: 1436-48. PMID 301172 DOI: 10.1084/Jem.145.6.1436 |
0.373 |
|
Low-probability matches (unlikely to be authored by this person) |
2004 |
Sasahara Y, Ramesh N, Tsuchiya S, Geha RS. WIP-Mediated Mechanisms of Recruitment, Activation and Degradation of WASP in T Cells. Blood. 104: 599-599. DOI: 10.1182/blood.v104.11.599.599 |
0.298 |
|
2021 |
Bainter W, Platt CD, Park SY, Stafstrom K, Wallace JG, Peters ZT, Massaad MJ, Becuwe M, Salinas SA, Jones J, Beaussant-Cohen S, Jaber F, Yang JS, Walther TC, Orange JS, ... ... Geha RS, et al. Combined immunodeficiency due to a mutation in the γ1 subunit of the coat protein I complex. The Journal of Clinical Investigation. 131. PMID 33529166 DOI: 10.1172/JCI140494 |
0.298 |
|
2014 |
Ramesh N, Massaad MJ, Kumar L, Koduru S, Sasahara Y, Anton I, Bhasin M, Libermann T, Geha R. Binding of the WASP/N-WASP-interacting protein WIP to actin regulates focal adhesion assembly and adhesion. Molecular and Cellular Biology. 34: 2600-10. PMID 24797074 DOI: 10.1128/Mcb.00017-14 |
0.298 |
|
2015 |
Dobbs K, Domínguez Conde C, Zhang SY, Parolini S, Audry M, Chou J, Haapaniemi E, Keles S, Bilic I, Okada S, Massaad MJ, Rounioja S, Alwahadneh AM, Serwas NK, Capuder K, ... ... Geha RS, et al. Inherited DOCK2 Deficiency in Patients with Early-Onset Invasive Infections. The New England Journal of Medicine. 372: 2409-22. PMID 26083206 DOI: 10.1056/Nejmoa1413462 |
0.297 |
|
2015 |
Aydin SE, Kilic SS, Aytekin C, Kumar A, Porras O, Kainulainen L, Kostyuchenko L, Genel F, Kütükcüler N, Karaca N, Gonzalez-Granado L, Abbott J, Al-Zahrani D, Rezaei N, Baz Z, ... ... Geha R, et al. DOCK8 deficiency: clinical and immunological phenotype and treatment options - a review of 136 patients. Journal of Clinical Immunology. 35: 189-98. PMID 25627830 DOI: 10.1007/S10875-014-0126-0 |
0.297 |
|
2002 |
MacGinnitie AJ, Geha R. X-linked lymphoproliferative disease: genetic lesions and clinical consequences. Current Allergy and Asthma Reports. 2: 361-367. PMID 12165201 DOI: 10.1007/S11882-002-0068-0 |
0.296 |
|
1990 |
Karp DR, Teletski CL, Scholl P, Geha R, Long EO. The α1 domain of the HLA-DR molecule is essential for high-affinity binding of the toxic shock syndrome toxin-1 Nature. 346: 474-476. PMID 2377209 DOI: 10.1038/346474A0 |
0.295 |
|
2015 |
Jabara HH, Boyden SE, Chou J, Ramesh N, Massaad MJ, Benson H, Bainter W, Fraulino D, Rahimov F, Sieff C, Liu ZJ, Alshemmari SH, Al-Ramadi BK, Al-Dhekri H, Arnaout R, ... ... Geha RS, et al. A missense mutation in TFRC, encoding transferrin receptor 1, causes combined immunodeficiency. Nature Genetics. PMID 26642240 DOI: 10.1038/Ng.3465 |
0.292 |
|
1978 |
Parkman R, Rappeport J, Geha R, Belli J, Cassady R, Levey R, Rosen FS. 725 Successful Correction Of A Bone Marrow Stem Cell Defect (Wiskott-Aldrich Syndrome) By Allogeneic Marrow Transplantation Pediatric Research. 12: 484-484. DOI: 10.1203/00006450-197804001-00730 |
0.292 |
|
2017 |
Schepp J, Chou J, Skrabl-Baumgartner A, Arkwright PD, Engelhardt KR, Hambleton S, Morio T, Röther E, Warnatz K, Geha R, Grimbacher B. 14 Years after Discovery: Clinical Follow-up on 15 Patients with Inducible Co-Stimulator Deficiency. Frontiers in Immunology. 8: 964. PMID 28861081 DOI: 10.3389/Fimmu.2017.00964 |
0.291 |
|
2017 |
Platt CD, Chou J, Houlihan P, Badran YR, Kumar L, Bainter W, Poliani PL, Perez CJ, Dent SY, Clapham DE, Benavides F, Geha RS. LRRC8A-dependent volume regulated anion channel activity is dispensable for T cell development and function. The Journal of Allergy and Clinical Immunology. PMID 28192143 DOI: 10.1016/J.Jaci.2016.12.974 |
0.29 |
|
1995 |
Chu YW, Marin E, Fuleihan R, Ramesh N, Rosen FS, Geha RS, Insel RA. Somatic mutation of human immunoglobulin V genes in the X-linked HyperIgM syndrome. The Journal of Clinical Investigation. 95: 1389-93. PMID 7533792 DOI: 10.1172/Jci117791 |
0.289 |
|
2006 |
Elkhal A, Pichavant M, Geha R, Umetsu D. Role of Natural Killer T-Cells in a Murine Model of Atopic Dermatitis (AD) Journal of Allergy and Clinical Immunology. 117: S234. DOI: 10.1016/J.Jaci.2005.12.925 |
0.289 |
|
2006 |
de la Fuente MA, Kumar L, Lu B, Geha RS. 3BP2 deficiency impairs the response of B cells, but not T cells, to antigen receptor ligation. Molecular and Cellular Biology. 26: 5214-25. PMID 16809760 DOI: 10.1128/MCB.00087-06 |
0.288 |
|
2004 |
Notarangelo L, Casanova JL, Fischer A, Puck J, Rosen F, Seger R, Geha R. Primary immunodeficiency diseases: an update. The Journal of Allergy and Clinical Immunology. 114: 677-87. PMID 15356576 DOI: 10.1016/J.Jaci.2004.06.044 |
0.287 |
|
1980 |
Matthews WJ, Williams M, Oliphint B, Geha R, Colten HR. Hypogammaglobulinemia in patients with cystic fibrosis. The New England Journal of Medicine. 302: 245-9. PMID 7350477 DOI: 10.1056/Nejm198001313020501 |
0.287 |
|
2008 |
Sasahara Y, de la Fuente MA, Ramesh N, Tsuchiya S, Geha RS. WIP Is a Chaperone for Wiskott-Aldrich Syndrome Protein. Blood. 112: 1471-1471. DOI: 10.1182/BLOOD.V112.11.1471.1471 |
0.286 |
|
2016 |
Alkhairy OK, Abolhassani H, Rezaei N, Fang M, Andersen KK, Chavoshzadeh Z, Mohammadzadeh I, El-Rajab MA, Massaad M, Chou J, Aghamohammadi A, Geha RS, Hammarström L. Spectrum of Phenotypes Associated with Mutations in LRBA. Journal of Clinical Immunology. 36: 33-45. PMID 26707784 DOI: 10.1007/S10875-015-0224-7 |
0.286 |
|
2020 |
Almutairi A, Wallace JG, Jaber F, Alosaimi MF, Jones J, Sallam MTH, Elnagdy MH, Chou J, Sobh A, Geha RS. Severe combined immunodeficiency caused by Inositol-trisphosphate 3-Kinase B (ITPKB) deficiency. The Journal of Allergy and Clinical Immunology. PMID 31987846 DOI: 10.1016/j.jaci.2020.01.014 |
0.285 |
|
2006 |
Du W, Kumaki S, Uchiyama T, Yachie A, Yeng Looi C, Kawai S, Minegishi M, Ramesh N, Geha RS, Sasahara Y, Tsuchiya S. A second-site mutation in the initiation codon of WAS (WASP) results in expansion of subsets of lymphocytes in an Wiskott-Aldrich syndrome patient. Human Mutation. 27: 370-5. PMID 16511828 DOI: 10.1002/HUMU.20308 |
0.285 |
|
1989 |
Leung DY, Geha RS. Regulation of the human IgE antibody response. International Reviews of Immunology. 2: 75-91. PMID 2976801 DOI: 10.3109/08830188709044748 |
0.285 |
|
2002 |
Antón IM, de la Fuente MA, Sims TN, Freeman S, Ramesh N, Hartwig JH, Dustin ML, Geha RS. WIP deficiency reveals a differential role for WIP and the actin cytoskeleton in T and B cell activation. Immunity. 16: 193-204. PMID 11869681 DOI: 10.1016/S1074-7613(02)00268-6 |
0.284 |
|
2012 |
Jabara HH, McDonald DR, Janssen E, Massaad MJ, Ramesh N, Borzutzky A, Rauter I, Benson H, Schneider L, Baxi S, Recher M, Notarangelo LD, Wakim R, Dbaibo G, Dasouki M, ... ... Geha RS, et al. DOCK8 functions as an adaptor that links TLR-MyD88 signaling to B cell activation. Nature Immunology. 13: 612-20. PMID 22581261 DOI: 10.1038/Ni.2305 |
0.284 |
|
2015 |
Yee CS, Massaad MJ, Bainter W, Ohsumi TK, Föger N, Chan AC, Akarsu NA, Aytekin C, Ayvaz DÇ, Tezcan I, Sanal Ö, Geha RS, Chou J. Recurrent viral infections associated with a homozygous CORO1A mutation that disrupts oligomerization and cytoskeletal association. The Journal of Allergy and Clinical Immunology. PMID 26476480 DOI: 10.1016/J.Jaci.2015.08.020 |
0.283 |
|
1987 |
Geha RS, Leung DY. Regulation of the human allergic response. International Archives of Allergy and Applied Immunology. 82: 389-91. PMID 3553028 DOI: 10.1159/000234234 |
0.283 |
|
2015 |
Gerasimcik N, Dahlberg CI, Baptista MA, Massaad MJ, Geha RS, Westerberg LS, Severinson E. The Rho GTPase Cdc42 Is Essential for the Activation and Function of Mature B Cells. Journal of Immunology (Baltimore, Md. : 1950). 194: 4750-8. PMID 25870239 DOI: 10.4049/Jimmunol.1401634 |
0.282 |
|
2004 |
Orange JS, Levy O, Brodeur SR, Krzewski K, Roy RM, Niemela JE, Fleisher TA, Bonilla FA, Geha RS. Human nuclear factor kappa B essential modulator mutation can result in immunodeficiency without ectodermal dysplasia. The Journal of Allergy and Clinical Immunology. 114: 650-6. PMID 15356572 DOI: 10.1016/J.Jaci.2004.06.052 |
0.281 |
|
2006 |
Rachid R, Castigli E, Geha RS, Bonilla FA. TACI mutation in common variable immunodeficiency and IgA deficiency. Current Allergy and Asthma Reports. 6: 357-62. PMID 16899196 DOI: 10.1007/s11882-996-0004-9 |
0.279 |
|
2014 |
Chou JS, Yee CS, Bainter W, Notarangelo LD, Al-Hammadi SM, Geha RS. A Novel ORAI1 Mutation Resulting In T+B+NK+ SCID With Normal Lymphocyte Proliferation Journal of Allergy and Clinical Immunology. 133: AB94. DOI: 10.1016/j.jaci.2013.12.350 |
0.279 |
|
2012 |
Recher M, Burns SO, de la Fuente MA, Volpi S, Dahlberg C, Walter JE, Moffitt K, Mathew D, Honke N, Lang PA, Patrizi L, Falet H, Keszei M, Mizui M, Csizmadia E, ... ... Geha RS, et al. B cell-intrinsic deficiency of the Wiskott-Aldrich syndrome protein (WASp) causes severe abnormalities of the peripheral B-cell compartment in mice. Blood. 119: 2819-28. PMID 22302739 DOI: 10.1182/Blood-2011-09-379412 |
0.278 |
|
2008 |
Pai SY, Levy O, Jabara HH, Glickman JN, Stoler-Barak L, Sachs J, Nurko S, Orange JS, Geha RS. Allogeneic transplantation successfully corrects immune defects, but not susceptibility to colitis, in a patient with nuclear factor-kappaB essential modulator deficiency. The Journal of Allergy and Clinical Immunology. 122: 1113-1118.e1. PMID 18851875 DOI: 10.1016/J.Jaci.2008.08.026 |
0.278 |
|
2004 |
Orange JS, Jain A, Ballas ZK, Schneider LC, Geha RS, Bonilla FA. The presentation and natural history of immunodeficiency caused by nuclear factor kappaB essential modulator mutation. The Journal of Allergy and Clinical Immunology. 113: 725-33. PMID 15100680 DOI: 10.1016/J.Jaci.2004.01.762 |
0.278 |
|
2016 |
Aydin S, Freeman AF, Su H, Hickstein D, Pai S, Geha R, Chatila T, Arnaout RK, Al-Mousa H, Al-Dhekri H, Renner ED, Belohradsky BH, Notheis G, Aydin R, Gaspar BH, et al. HSCT for DOCK8 Deficiency - an International Study on 74 Patients Biology of Blood and Marrow Transplantation. 22. DOI: 10.1016/J.Bbmt.2015.11.406 |
0.277 |
|
2022 |
Janssen E, Alosaimi MF, Alazami AM, Alsuliman A, Alaiya A, Al-Saud B, Al-Mousa H, Al-Zaid TJ, Smith E, Platt CD, Alruwaili H, Albanyan S, Al-Mayouf SM, Geha RS. A homozygous truncating mutation of FGL2 is associated with immune dysregulation. The Journal of Allergy and Clinical Immunology. PMID 36243222 DOI: 10.1016/j.jaci.2022.10.006 |
0.277 |
|
2017 |
Chinen J, Badran Y, Geha RS, Chou JS, Fried AJ. Advances in Basic and Clinical Immunology 2016. The Journal of Allergy and Clinical Immunology. PMID 28826774 DOI: 10.1016/j.jaci.2017.07.023 |
0.277 |
|
1985 |
Leung DY, Geha RS. Regulation of human IgE synthesis. The Journal of Investigative Dermatology. 85: 155s-160s. PMID 2989377 DOI: 10.1111/1523-1747.ep12275700 |
0.275 |
|
2003 |
Yan C, Martinez-Quiles N, Eden S, Shibata T, Takeshima F, Shinkura R, Fujiwara Y, Bronson R, Snapper SB, Kirschner MW, Geha R, Rosen FS, Alt FW. WAVE2 deficiency reveals distinct roles in embryogenesis and Rac-mediated actin-based motility. The Embo Journal. 22: 3602-12. PMID 12853475 DOI: 10.1093/Emboj/Cdg350 |
0.275 |
|
2001 |
Snapper SB, Takeshima F, Antón I, Liu CH, Thomas SM, Nguyen D, Dudley D, Fraser H, Purich D, Lopez-Ilasaca M, Klein C, Davidson L, Bronson R, Mulligan RC, Southwick F, ... Geha R, et al. N-WASP deficiency reveals distinct pathways for cell surface projections and microbial actin-based motility. Nature Cell Biology. 3: 897-904. PMID 11584271 DOI: 10.1038/Ncb1001-897 |
0.274 |
|
2014 |
Hedayat M, Massaad MJ, Lee YN, Conley ME, Orange JS, Ohsumi TK, Al-Herz W, Notarangelo LD, Geha RS, Chou J. Lessons in gene hunting: a RAG1 mutation presenting with agammaglobulinemia and absence of B cells. The Journal of Allergy and Clinical Immunology. 134: 983-5.e1. PMID 24985406 DOI: 10.1016/J.Jaci.2014.04.037 |
0.274 |
|
2016 |
Biswas A, Shouval D, Goettel J, Field M, Griffith A, Pai SY, Notarangelo L, Geha R, Snapper S. O-008 Aberrant Anti-inflammatory Macrophage Function and Differentiation in Wiskott-Aldrich Syndrome Protein-Deficient Mice and Humans. Inflammatory Bowel Diseases. 22: S3. PMID 26849726 DOI: 10.1097/01.Mib.0000480046.11503.1E |
0.273 |
|
2004 |
Castigli E, Scott S, Dedeoglu F, Bryce P, Jabara H, Bhan AK, Mizoguchi E, Geha RS. Impaired IgA class switching in APRIL-deficient mice. Proceedings of the National Academy of Sciences of the United States of America. 101: 3903-8. PMID 14988498 DOI: 10.1073/PNAS.0307348101 |
0.273 |
|
2021 |
Garcia de Mattos Barbosa M, Lefferts AR, Huynh D, Liu H, Zhang Y, Fu B, Barnes J, Samaniego M, Bram RJ, Geha R, Shikanov A, Luning Prak ET, Farkash EA, Platt JL, Cascalho M. TNFRSF13B genotypes control immune-mediated pathology by regulating the functions of innate B cells. Jci Insight. PMID 34283811 DOI: 10.1172/jci.insight.150483 |
0.272 |
|
2007 |
Antón IM, Jones GE, Wandosell F, Geha R, Ramesh N. WASP-interacting protein (WIP): working in polymerisation and much more. Trends in Cell Biology. 17: 555-62. PMID 17949983 DOI: 10.1016/J.Tcb.2007.08.005 |
0.271 |
|
2007 |
Jin H, Mathias C, Young D, Collins M, Grusby M, Oettgen H, Geha R. An Essential Role For Il-21R In The Immune Response To Epicutaneous Sensitization In A Mouse Model Of Atopic Dermatitis Journal of Allergy and Clinical Immunology. 119: 523-524. DOI: 10.1016/J.Jaci.2006.12.628 |
0.27 |
|
1998 |
Pivniouk V, Tsitsikov E, Swinton P, Rathbun G, Alt FW, Geha RS. Impaired viability and profound block in thymocyte development in mice lacking the adaptor protein SLP-76. Cell. 94: 229-38. PMID 9695951 DOI: 10.1016/S0092-8674(00)81422-1 |
0.27 |
|
2020 |
Kerner G, Rosain J, Guérin A, AlKhabaz A, Oleaga-Quintas C, Rapaport F, Massaad MJ, Ding JY, Khan T, Al Ali F, Rahman M, Deswarte C, Martinez-Barricarte R, Geha RS, Jeanne-Julien V, et al. Inherited human IFNγ deficiency underlies mycobacterial disease. The Journal of Clinical Investigation. PMID 32163377 DOI: 10.1172/Jci135460 |
0.27 |
|
2014 |
Kumar L, Chou J, Yee CS, Borzutzky A, Vollmann EH, von Andrian UH, Park SY, Hollander G, Manis JP, Poliani PL, Geha RS. Leucine-rich repeat containing 8A (LRRC8A) is essential for T lymphocyte development and function. The Journal of Experimental Medicine. 211: 929-42. PMID 24752297 DOI: 10.1084/jem.20131379 |
0.269 |
|
2013 |
Recher M, Fried AJ, Massaad MJ, Kim HY, Rizzini M, Frugoni F, Walter JE, Mathew D, Eibel H, Hess C, Giliani S, Umetsu DT, Notarangelo LD, Geha RS. Intronic SH2D1A mutation with impaired SAP expression and agammaglobulinemia. Clinical Immunology (Orlando, Fla.). 146: 84-9. PMID 23280491 DOI: 10.1016/J.Clim.2012.11.007 |
0.268 |
|
2017 |
Leyva-Castillo J, Yoon J, Geha R. IL-22 Generated in Response to Cutaneous Sensitization Drives Neutrophilic Airway Inflammation Following Antigen Inhalation in a Mouse Model of Atopic Dermatitis Journal of Allergy and Clinical Immunology. 139: AB2. DOI: 10.1016/J.Jaci.2016.12.059 |
0.268 |
|
2013 |
Mizesko M, Banerjee P, Monaco-Shawver L, Mace E, Bernal W, Sawalle-Belohradsky J, Belohradsky B, Heinz V, Freeman A, Sullivan K, Holland S, Torgerson T, Al-Herz W, Chou J, Hanson I, ... ... Geha R, et al. A2.23 Impaired Natural Killer Cell Function in DOCK8 Deficiency Annals of the Rheumatic Diseases. 72: A12.3-A13. DOI: 10.1136/Annrheumdis-2013-203215.23 |
0.268 |
|
2017 |
Lougaris V, Chou J, Baronio M, Gazzurelli L, Lorenzini T, Soresina A, Moratto D, Badolato R, Seleman M, Bellettato M, Geha RS, Plebani A. Novel biallelic TRNT1 mutations resulting in sideroblastic anemia, combined B and T cell defects, hypogammaglobulinemia, recurrent infections, hypertrophic cardiomyopathy and developmental delay. Clinical Immunology (Orlando, Fla.). PMID 29170023 DOI: 10.1016/j.clim.2017.11.008 |
0.267 |
|
1978 |
Parkman R, Rappeport J, Geha R, Belli J, Cassady R, Levey R, Nathan DG, Rosen FS. Complete correction of the Wiskott Aldrich syndrome by allogeneic bone marrow transplantation New England Journal of Medicine. 298: 921-927. PMID 347289 DOI: 10.1056/Nejm197804272981701 |
0.266 |
|
2007 |
de la Fuente MA, Sasahara Y, Calamito M, Antón IM, Elkhal A, Gallego MD, Suresh K, Siminovitch K, Ochs HD, Anderson KC, Rosen FS, Geha RS, Ramesh N. WIP is a chaperone for Wiskott-Aldrich syndrome protein (WASP). Proceedings of the National Academy of Sciences of the United States of America. 104: 926-31. PMID 17213309 DOI: 10.1073/pnas.0610275104 |
0.265 |
|
1981 |
Siegel RL, Issekutz T, Schwaber J, Rosen FS, Geha RS. Deficiency of T helper cells in transient hypogammaglobulinemia of infancy. The New England Journal of Medicine. 305: 1307-13. PMID 6270560 DOI: 10.1056/NEJM198111263052202 |
0.265 |
|
2015 |
Chou J, Badran YR, Yee CS, Bainter W, Ohsumi TK, Al-Hammadi S, Pai SY, Feske S, Geha RS. A novel mutation in ORAI1 presenting with combined immunodeficiency and residual T-cell function. The Journal of Allergy and Clinical Immunology. 136: 479-82.e1. PMID 26070885 DOI: 10.1016/J.Jaci.2015.03.050 |
0.264 |
|
2001 |
Tsitsikov EN, Laouini D, Dunn IF, Sannikova TY, Davidson L, Alt FW, Geha RS. TRAF1 is a negative regulator of TNF signaling. enhanced TNF signaling in TRAF1-deficient mice. Immunity. 15: 647-57. PMID 11672546 DOI: 10.1016/S1074-7613(01)00207-2 |
0.263 |
|
1988 |
Lee BW, Geha RS, Leung DY. IgE response and its regulation in allergic diseases. Pediatric Clinics of North America. 35: 953-67. PMID 3050837 DOI: 10.1016/S0031-3955(16)36541-5 |
0.262 |
|
2020 |
Whangbo JS, Chou J, Al-Dhekri H, Harris M, Geha RS, Pai SY, Al-Herz W. Hematopoietic stem cell transplantation is a curative therapy for transferrin receptor 1 (TFRC) deficiency. The Journal of Allergy and Clinical Immunology. in Practice. PMID 33096268 DOI: 10.1016/j.jaip.2020.10.018 |
0.262 |
|
1996 |
Gorlin JB, Vamvakas EC, Cooke E, Galacki D, Geha R, Humphreys D, Kent P. Large‐volume leukapheresis in pediatric patients: processing more blood diminishes the apparent magnitude of intra‐apheresis recruitment Transfusion. 36: 879-885. PMID 8863774 DOI: 10.1046/J.1537-2995.1996.361097017173.X |
0.261 |
|
2020 |
Janssen E, Tohme M, Butts J, Giguere SS, Sage PT, Velázquez FE, Kam C, Milin E, Das M, Sobh A, Al-Tamemi S, Luscinskas FW, Batista F, Geha RS. DOCK8 is essential for LFA-1 dependent positioning of T follicular helper cells in germinal centers. Jci Insight. PMID 32573493 DOI: 10.1172/Jci.Insight.134508 |
0.259 |
|
2013 |
Jabara HH, Ohsumi T, Chou J, Massaad MJ, Benson H, Megarbane A, Chouery E, Mikhael R, Gorka O, Gewies A, Portales P, Nakayama T, Hosokawa H, Revy P, Herrod H, ... ... Geha RS, et al. A homozygous mucosa-associated lymphoid tissue 1 (MALT1) mutation in a family with combined immunodeficiency. The Journal of Allergy and Clinical Immunology. 132: 151-8. PMID 23727036 DOI: 10.1016/J.Jaci.2013.04.047 |
0.258 |
|
2006 |
Koduru S, Massaad M, Wilbur C, Kumar L, Geha R, Ramesh N. A novel anti-WIP monoclonal antibody detects an isoform of WIP that lacks the WASP binding domain. Biochemical and Biophysical Research Communications. 353: 875-81. PMID 17207458 DOI: 10.1016/J.Bbrc.2006.12.079 |
0.258 |
|
2018 |
Archer N, Lee S, Jo J, Kim D, Ortines R, Wang Y, Marchitto M, Ravipati A, Cai S, Dillen C, Liu H, Miller R, Ashbaugh A, Uppal A, Oyoshi M, ... ... Geha R, et al. 949 Skin microbiota alterations induce dysregulated IL-1α responses that drive atopic dermatitis-like skin inflammation Journal of Investigative Dermatology. 138: S161. DOI: 10.1016/J.Jid.2018.03.961 |
0.257 |
|
1986 |
Leung DYM, Young MC, Wood N, Geha RS. Induction of IgE synthesis in normal human B cells. Sequential requirements for activation by an alloreactive T cell clone and IgE-potentiating factors Journal of Experimental Medicine. 163: 713-723. PMID 2936863 DOI: 10.1084/jem.163.3.713 |
0.257 |
|
2009 |
Jin H, Kumar L, Mathias C, Oettgen H, Geha R, Zurakowski D. F.65. Toll-like Receptor 2 is Important for the Th1 Response to Cutaneous Sensitization Clinical Immunology. 131: S111. DOI: 10.1016/J.Clim.2009.03.326 |
0.257 |
|
1989 |
Vercelli D, Jabara HH, Arai K, Geha RS. Induction of human IgE synthesis requires interleukin 4 and T/B cell interactions involving the T cell receptor/CD3 complex and MHC class II antigens. The Journal of Experimental Medicine. 169: 1295-307. PMID 2522501 DOI: 10.1084/Jem.169.4.1295 |
0.257 |
|
2017 |
Qamar F, Junejo S, Qureshi S, Seleman M, Bainter W, Massaad M, Chou J, Geha RS. A novel mutation in the JH4 domain of JAK3 causing severe combined immunodeficiency complicated by vertebral osteomyelitis. Clinical Immunology (Orlando, Fla.). PMID 28917720 DOI: 10.1016/J.Clim.2017.09.007 |
0.257 |
|
2017 |
Yazdani R, Abolhassani H, Tafaroji J, Azizi G, Geha RS, Aghamohammadi A. Cernunnos deficiency associated with BCG adenitis and autoimmunity: First case from the national Iranian registry and review of the literature. Clinical Immunology (Orlando, Fla.). PMID 28729231 DOI: 10.1016/j.clim.2017.07.007 |
0.257 |
|
2005 |
Orange JS, Levy O, Geha RS. Human disease resulting from gene mutations that interfere with appropriate nuclear factor-kappaB activation. Immunological Reviews. 203: 21-37. PMID 15661019 DOI: 10.1111/J.0105-2896.2005.00221.X |
0.257 |
|
2015 |
Keppler SJ, Gasparrini F, Burbage M, Aggarwal S, Frederico B, Geha RS, Way M, Bruckbauer A, Batista FD. Wiskott-Aldrich Syndrome Interacting Protein Deficiency Uncovers the Role of the Co-receptor CD19 as a Generic Hub for PI3 Kinase Signaling in B Cells. Immunity. 43: 660-73. PMID 26453379 DOI: 10.1016/j.immuni.2015.09.004 |
0.256 |
|
1985 |
Umetsu DT, Leung DY, Siraganian R, Jabara HH, Geha RS. Differential requirements of B cells from normal and allergic subjects for the induction of IgE synthesis by an alloreactive T cell clone. The Journal of Experimental Medicine. 162: 202-14. PMID 3874259 DOI: 10.1084/jem.162.1.202 |
0.256 |
|
1994 |
Ramesh N, Fuleihan R, Geha R. Molecular pathology of X-linked immunoglobulin deficiency with normal or elevated IgM (HIGMX-1). Immunological Reviews. 138: 87-104. PMID 7520884 DOI: 10.1111/J.1600-065X.1994.Tb00848.X |
0.256 |
|
2021 |
Giardino G, Sharapova SO, Ciznar P, Dhalla F, Maragliano L, Radha Rama Devi A, Islamoglu C, Ikinciogullari A, Haskologlu S, Dogu F, Hanna-Wakim R, Dbaibo G, Chou J, Cirillo E, Borzacchiello C, ... ... Geha R, et al. Expanding the Nude SCID/CID Phenotype Associated with FOXN1 Homozygous, Compound Heterozygous, or Heterozygous Mutations. Journal of Clinical Immunology. PMID 33464451 DOI: 10.1007/s10875-021-00967-y |
0.255 |
|
2014 |
Janssen E, Morbach H, Ullas S, Bannock JM, Massad C, Menard L, Barlan I, Lefranc G, Su H, Dasouki M, Al-Herz W, Keles S, Chatila T, Geha RS, Meffre E. Dedicator of cytokinesis 8-deficient patients have a breakdown in peripheral B-cell tolerance and defective regulatory T cells. The Journal of Allergy and Clinical Immunology. 134: 1365-74. PMID 25218284 DOI: 10.1016/J.Jaci.2014.07.042 |
0.255 |
|
2018 |
Keppler SJ, Burbage M, Gasparrini F, Hartjes L, Aggarwal S, Massaad MJ, Geha RS, Bruckbauer A, Batista FD. The Lack of WIP Binding to Actin Results in Impaired B Cell Migration and Altered Humoral Immune Responses. Cell Reports. 24: 619-629. PMID 30021160 DOI: 10.1016/J.Celrep.2018.06.051 |
0.255 |
|
1988 |
Umetsu DT, Jabara HH, Hauschka P, Geha RS. Recognition by a human alloreactive T-cell clone of an HLA-DP-associated epitope on monocytes and fibroblasts but not on B cells. Journal of Clinical Immunology. 8: 163-70. PMID 2455729 DOI: 10.1007/Bf00917562 |
0.254 |
|
2022 |
Chatila TA, Benamar M, Chen Q, Chou J, Julé A, Boudra R, Contini P, Crestani E, Wang M, Fong J, Lai P, Rockwitz S, Lee P, Chan TMF, Altun EZ, ... ... Geha R, et al. Notch1-CD22-Dependent Immune Dysregulation in the SARS-CoV2-Associated Multisystem Inflammatory Syndrome in Children. Research Square. PMID 35441180 DOI: 10.21203/rs.3.rs-1054453/v1 |
0.254 |
|
2019 |
Janssen E, Geha RS. Primary immunodeficiencies caused by mutations in actin regulatory proteins. Immunological Reviews. 287: 121-134. PMID 30565251 DOI: 10.1111/Imr.12716 |
0.254 |
|
1994 |
Ramesh N, Parronchi P, Ahern D, Romagnani S, Geha R. A toxic shock syndrome toxin-1 peptide that shows homology to amino acids 180-193 of mycobacterial heat shock protein 65 is presented as conventional antigen. Immunological Investigations. 23: 381-391. PMID 7851957 DOI: 10.3109/08820139409066833 |
0.254 |
|
2008 |
Ozcan E, Notarangelo LD, Geha RS. Primary immune deficiencies with aberrant IgE production. The Journal of Allergy and Clinical Immunology. 122: 1054-62; quiz 1063-4. PMID 19084106 DOI: 10.1016/j.jaci.2008.10.023 |
0.254 |
|
1973 |
Geha RS, Schneeberger E, Rosen FS, Merler E. Interaction of human thymus-derived and non-thymus-derived lymphocytes in vitro. Induction of proliferation and antibody synthesis in B lymphocytes by a soluble factor released from antigen-stimulated T lymphocytes. The Journal of Experimental Medicine. 138: 1230-47. PMID 4200776 DOI: 10.1084/jem.138.5.1230 |
0.254 |
|
2016 |
Keles S, Charbonnier LM, Kabaleeswaran V, Reisli I, Genel F, Gulez N, Al-Herz W, Ramesh N, Perez-Atayde A, Eeder NK, Kutukculer N, Wu H, Geha RS, Chatila TA. Dedicator of cytokinesis 8 regulates signal transducer and activator of transcription 3 activation and promotes TH17 cell differentiation. The Journal of Allergy and Clinical Immunology. PMID 27350570 DOI: 10.1016/j.jaci.2016.04.023 |
0.254 |
|
2009 |
Bonilla FA, Geha RS. Common variable immunodeficiency. Pediatric Research. 65: 13R-19R. PMID 19190529 DOI: 10.1203/PDR.0b013e31819dbf88 |
0.252 |
|
1996 |
Holländer GA, Castigli E, Kulbacki R, Su M, Burakoff SJ, Gutierrez-Ramos JC, Geha RS. Induction of alloantigen-specific tolerance by B cells from CD40-deficient mice. Proceedings of the National Academy of Sciences of the United States of America. 93: 4994-8. PMID 8643517 DOI: 10.1073/Pnas.93.10.4994 |
0.251 |
|
2006 |
Le Bras S, Geha RS. IPEX and the role of Foxp3 in the development and function of human Tregs. The Journal of Clinical Investigation. 116: 1473-5. PMID 16741571 DOI: 10.1172/JCI28880 |
0.251 |
|
1979 |
Reinherz EL, Rubinstein A, Geha RS, Strelkauskas AJ, Rosen FS, Schlossman SF. Abnormalities of immunoregulatory T cells in disorders of immune function. The New England Journal of Medicine. 301: 1018-22. PMID 158708 DOI: 10.1056/NEJM197911083011902 |
0.25 |
|
2013 |
Massaad MJ, Ramesh N, Geha RS. Wiskott-Aldrich syndrome: a comprehensive review. Annals of the New York Academy of Sciences. 1285: 26-43. PMID 23527602 DOI: 10.1111/Nyas.12049 |
0.25 |
|
1979 |
Geha RS, Hyslop N, Alami S, Farah F, Schneeberger EE, Rosen FS. Hyper immunoglobulin M immunodeficiency. (Dysgammaglobulinemia). Presence of immunoglobulin M-secreting plasmacytoid cells in peripheral blood and failure of immunoglobulin M-immunoglobulin G switch in B-cell differentiation. The Journal of Clinical Investigation. 64: 385-91. PMID 313404 DOI: 10.1172/JCI109473 |
0.249 |
|
2019 |
Alosaimi M, Hoenig M, Jaber F, Platt CD, Jones J, Wallace J, Debatin KM, Schulz A, Jacobsen E, Möller P, Shamseldin HE, Abdulwahab F, Ibrahim N, Alardati H, Almuhizi F, ... ... Geha RS, et al. Immunodeficiency and Epstein Barr virus induced lymphoproliferation caused by 4-1BB deficiency. The Journal of Allergy and Clinical Immunology. PMID 30872117 DOI: 10.1016/J.Jaci.2019.03.002 |
0.249 |
|
2022 |
Benamar M, Chen Q, Chou J, Julé AM, Boudra R, Contini P, Crestani E, Lai PS, Wang M, Fong J, Rockwitz S, Lee PY, Chan TMF, Altun EZ, Kepenekli E, ... ... Geha RS, et al. The Notch1/CD22 signaling axis disrupts Treg cell function in SARS-CoV2-associated multisystem inflammatory syndrome in children. The Journal of Clinical Investigation. PMID 36282598 DOI: 10.1172/JCI163235 |
0.249 |
|
2000 |
Dunn I, Geha R, Tsitsikov E. 540 CD40-inducible expression of the TRAF1 gene is controlled by two enhancers The Journal of Allergy and Clinical Immunology. 105. DOI: 10.1016/S0091-6749(00)90968-0 |
0.249 |
|
1995 |
Castigli E, Alt FW, Davidson L, Bottaro A, Mizoguchi E, Bhan AK, Geha RS. CD40-deficient mice generated by recombination-activating gene-2-deficient blastocyst complementation. Proceedings of the National Academy of Sciences of the United States of America. 91: 12135-9. PMID 7527552 DOI: 10.1073/Pnas.91.25.12135 |
0.247 |
|
2005 |
Cianferoni A, Massaad M, Feske S, de la Fuente MA, Gallego L, Ramesh N, Geha RS. Defective nuclear translocation of nuclear factor of activated T cells and extracellular signal-regulated kinase underlies deficient IL-2 gene expression in Wiskott-Aldrich syndrome. The Journal of Allergy and Clinical Immunology. 116: 1364-71. PMID 16337472 DOI: 10.1016/J.Jaci.2005.09.006 |
0.246 |
|
2009 |
Le Bras S, Massaad M, Koduru S, Kumar L, Oyoshi MK, Hartwig J, Geha RS. WIP is critical for T cell responsiveness to IL-2. Proceedings of the National Academy of Sciences of the United States of America. 106: 7519-24. PMID 19359486 DOI: 10.1073/Pnas.0806410106 |
0.246 |
|
1985 |
Leung DYM, Young MC, Geha RS. Secretion of IgE-specific potentiating factors by human Fc<inf>ε</inf>R+ T cell lines International Archives of Allergy and Immunology. 77: 232-234. PMID 3159683 DOI: 10.1159/000233796 |
0.246 |
|
2010 |
He R, Geha RS. Thymic stromal lymphopoietin. Annals of the New York Academy of Sciences. 1183: 13-24. PMID 20146705 DOI: 10.1111/j.1749-6632.2009.05128.x |
0.246 |
|
2017 |
Alroqi FJ, Charbonnier LM, Baris S, Kiykim A, Chou J, Platt CD, Algassim A, Keles S, Al Saud BK, Alkuraya FS, Jordan M, Geha RS, Chatila TA. Exaggerated T Follicular Helper Cell Responses in LRBA Deficiency Due to Failure of CTLA4-Mediated Regulation. The Journal of Allergy and Clinical Immunology. PMID 28601686 DOI: 10.1016/J.Jaci.2017.05.022 |
0.245 |
|
1997 |
Jabara HH, Geha RS. The superantigen toxic shock syndrome toxin-1 induces CD40 ligand expression and modulates IgE isotype switching. International Immunology. 8: 1503-10. PMID 8921429 DOI: 10.1093/intimm/8.10.1503 |
0.245 |
|
2019 |
Platt CD, Zaman F, Wallace JG, Seleman M, Chou J, Al Sukaiti N, Geha RS. A novel truncating mutation in MYD88 in a patient with BCG adenitis, neutropenia and delayed umbilical cord separation. Clinical Immunology (Orlando, Fla.). PMID 31301515 DOI: 10.1016/J.Clim.2019.07.004 |
0.245 |
|
2018 |
Bao J, Perez CJ, Kim J, Zhang H, Murphy CJ, Hamidi T, Jaubert J, Platt CD, Chou J, Deng M, Zhou MH, Huang Y, Gaitán-Peñas H, Guénet JL, Lin K, ... ... Geha RS, et al. Deficient LRRC8A-dependent volume-regulated anion channel activity is associated with male infertility in mice. Jci Insight. 3. PMID 30135305 DOI: 10.1172/Jci.Insight.99767 |
0.244 |
|
2005 |
Kumar L, Feske S, Rao A, Geha RS. A 10-aa-long sequence in SLP-76 upstream of the Gads binding site is essential for T cell development and function. Proceedings of the National Academy of Sciences of the United States of America. 102: 19063-8. PMID 16354835 DOI: 10.1073/Pnas.0509176102 |
0.244 |
|
1984 |
Parkman R, Rappeport J, Hellman S, Lipton J, Smith B, Geha R, Nathan D. Busulfan and total body irradiation as antihematopoietic stem cell agents in the preparation of patients with congenital bone marrow disorders for allogenic bone marrow transplantation Blood. 64: 852-857. DOI: 10.1182/Blood.V64.4.852.852 |
0.244 |
|
2013 |
Mizesko MC, Banerjee PP, Monaco-Shawver L, Mace EM, Bernal WE, Sawalle-Belohradsky J, Belohradsky BH, Heinz V, Freeman AF, Sullivan KE, Holland SM, Torgerson TR, Al-Herz W, Chou J, Hanson IC, ... ... Geha RS, et al. Defective actin accumulation impairs human natural killer cell function in patients with dedicator of cytokinesis 8 deficiency. The Journal of Allergy and Clinical Immunology. 131: 840-8. PMID 23380217 DOI: 10.1016/J.Jaci.2012.12.1568 |
0.244 |
|
1993 |
Fuleihan R, Ramesh N, Loh R, Jabara H, Rosen RS, Chatila T, Fu SM, Stamenkovic I, Geha RS. Defective expression of the CD40 ligand in X chromosome-linked immunoglobulin deficiency with normal or elevated IgM. Proceedings of the National Academy of Sciences of the United States of America. 90: 2170-3. PMID 7681587 DOI: 10.1073/pnas.90.6.2170 |
0.244 |
|
2004 |
Dai YS, Liang MG, Gellis SE, Bonilla FA, Schneider LC, Geha RS, Orange JS. Characteristics of mycobacterial infection in patients with immunodeficiency and nuclear factor-kappaB essential modulator mutation, with or without ectodermal dysplasia. Journal of the American Academy of Dermatology. 51: 718-22. PMID 15523349 DOI: 10.1016/J.Jaad.2004.05.032 |
0.243 |
|
2002 |
Arima K, Umeshita-Suyama R, Sakata Y, Akaiwa M, Mao X, Enomoto T, Dake Y, Shimazu S, Yamashita T, Sugawara N, Brodeur S, Geha R, Puri RK, Sayegh MH, Adra CN, et al. Upregulation of IL-13 concentration in vivo by the IL13 variant associated with bronchial asthma The Journal of Allergy and Clinical Immunology. 109: 980-987. PMID 12063528 DOI: 10.1067/Mai.2002.124656 |
0.243 |
|
2001 |
Woodward AL, Spergel JM, Alenius H, Mizoguchi E, Bhan AK, Castigli E, Brodeur SR, Oettgen HC, Geha RS. An obligate role for T-cell receptor alphabeta+ T cells but not T-cell receptor gammadelta+ T cells, B cells, or CD40/CD40L interactions in a mouse model of atopic dermatitis. The Journal of Allergy and Clinical Immunology. 107: 359-66. PMID 11174205 DOI: 10.1067/mai.2001.112695 |
0.242 |
|
2014 |
Günaydin NC, Chou J, Karaca NE, Aksu G, Massaad MJ, Azarsiz E, Ertan Y, Geha RS, Kütükçüler N. A novel disease-causing CD40L mutation reduces expression of CD40 ligand, but preserves CD40 binding capacity. Clinical Immunology (Orlando, Fla.). 153: 288-91. PMID 24845792 DOI: 10.1016/J.Clim.2014.05.001 |
0.242 |
|
2010 |
Koduru S, Kumar L, Massaad MJ, Ramesh N, Le Bras S, Ozcan E, Oyoshi MK, Kaku M, Fujiwara Y, Kremer L, King S, Fuhlbrigge R, Rodig S, Sage P, Carman C, ... ... Geha RS, et al. Cdc42 interacting protein 4 (CIP4) is essential for integrin-dependent T-cell trafficking. Proceedings of the National Academy of Sciences of the United States of America. 107: 16252-6. PMID 20805498 DOI: 10.1073/Pnas.1002747107 |
0.242 |
|
1993 |
Ramesh N, Fuleihan R, Ramesh V, Lederman S, Yellin MJ, Sharma S, Chess L, Rosen FS, Geha RS. Deletions in the ligand for CD40 in X-linked immunoglobulin deficiency with normal or elevated IgM (HIGMX-1) International Immunology. 5: 769-773. PMID 8103673 DOI: 10.1093/Intimm/5.7.769 |
0.242 |
|
2017 |
Janssen E, Kumari S, Tohme M, Ullas S, Barrera V, Tas JM, Castillo-Rama M, Bronson RT, Usmani SM, Irvine DJ, Mempel TR, Geha RS. DOCK8 enforces immunological tolerance by promoting IL-2 signaling and immune synapse formation in Tregs. Jci Insight. 2. PMID 28978806 DOI: 10.1172/Jci.Insight.94298 |
0.241 |
|
1986 |
Young M, Geha RS, Maksad KN, Leung DY. Characterization of human T cell-derived IgE-potentiating factor. European Journal of Immunology. 16: 985-91. PMID 3488913 DOI: 10.1002/eji.1830160819 |
0.24 |
|
1994 |
Loh RK, Jabara HH, Geha RS. Disodium cromoglycate inhibits S mu-->S epsilon deletional switch recombination and IgE synthesis in human B cells. The Journal of Experimental Medicine. 180: 663-71. PMID 8046339 DOI: 10.1084/jem.180.2.663 |
0.24 |
|
2002 |
Orange JS, Ramesh N, Remold-O'Donnell E, Sasahara Y, Koopman L, Byrne M, Bonilla FA, Rosen FS, Geha RS, Strominger JL. Wiskott-Aldrich syndrome protein is required for NK cell cytotoxicity and colocalizes with actin to NK cell-activating immunologic synapses. Proceedings of the National Academy of Sciences of the United States of America. 99: 11351-6. PMID 12177428 DOI: 10.1073/Pnas.162376099 |
0.24 |
|
2012 |
Lanzi G, Moratto D, Vairo D, Masneri S, Delmonte O, Paganini T, Parolini S, Tabellini G, Mazza C, Savoldi G, Montin D, Martino S, Tovo P, Pessach IM, Massaad MJ, ... ... Geha RS, et al. A novel primary human immunodeficiency due to deficiency in the WASP-interacting protein WIP. The Journal of Experimental Medicine. 209: 29-34. PMID 22231303 DOI: 10.1084/Jem.20110896 |
0.24 |
|
2014 |
Chou J, Massaad MJ, Wakim RH, Bainter W, Dbaibo G, Geha RS. A novel mutation in FOXN1 resulting in SCID: a case report and literature review. Clinical Immunology (Orlando, Fla.). 155: 30-2. PMID 25173801 DOI: 10.1016/J.Clim.2014.08.005 |
0.239 |
|
1989 |
Chatila T, Wong R, Young M, Miller R, Terhorst C, Geha RS. An immunodeficiency characterized by defective signal transduction in T lymphocytes. The New England Journal of Medicine. 320: 696-702. PMID 2784191 DOI: 10.1056/NEJM198903163201104 |
0.239 |
|
2017 |
Badran YR, Dedeoglu F, Leyva Castillo JM, Bainter W, Ohsumi TK, Bousvaros A, Goldsmith JD, Geha RS, Chou J. Human RELA haploinsufficiency results in autosomal-dominant chronic mucocutaneous ulceration. The Journal of Experimental Medicine. PMID 28600438 DOI: 10.1084/jem.20160724 |
0.238 |
|
2001 |
Jabara HH, Brodeur SR, Geha RS. Glucocorticoids upregulate CD40 ligand expression and induce CD40L-dependent immunoglobulin isotype switching. The Journal of Clinical Investigation. 107: 371-8. PMID 11160161 DOI: 10.1172/JCI10168 |
0.238 |
|
2022 |
Jabara HH, McDonald DR, Janssen E, Massaad MJ, Ramesh N, Borzutzky A, Rauter I, Benson H, Schneider L, Baxi S, Recher M, Notarangelo LD, Wakim R, Dbaibo G, Dasouki M, ... ... Geha RS, et al. Author Correction: DOCK8 functions as an adaptor that links TLR-MyD88 signaling to B cell activation. Nature Immunology. PMID 35332329 DOI: 10.1038/s41590-022-01180-8 |
0.238 |
|
2002 |
Kumar L, Pivniouk V, de la Fuente MA, Laouini D, Geha RS. Differential role of SLP-76 domains in T cell development and function. Proceedings of the National Academy of Sciences of the United States of America. 99: 884-9. PMID 11792851 DOI: 10.1073/PNAS.022619199 |
0.238 |
|
1995 |
Horner AA, Jabara H, Ramesh N, Geha RS. gamma/delta T lymphocytes express CD40 ligand and induce isotype switching in B lymphocytes. The Journal of Experimental Medicine. 181: 1239-44. PMID 7869041 DOI: 10.1084/jem.181.3.1239 |
0.236 |
|
2017 |
Hoyos-Bachiloglu R, Chou J, Sodroski CN, Beano A, Bainter W, Angelova M, Al Idrissi E, Habazi MK, Alghamdi HA, Almanjomi F, Al Shehri M, Elsidig N, Alaa Eldin M, Knipe DM, AlZahrani M, ... Geha RS, et al. A digenic human immunodeficiency characterized by IFNAR1 and IFNGR2 mutations. The Journal of Clinical Investigation. PMID 29106381 DOI: 10.1172/Jci93486 |
0.236 |
|
2018 |
Qureshi S, Sheikh MDA, Qamar FN, Bainter W, Chou J, Geha RS. Autosomal Recessive Agammaglobulinemia - first case with a novel TCF3 mutation from Pakistan. Clinical Immunology (Orlando, Fla.). PMID 30063982 DOI: 10.1016/j.clim.2018.07.016 |
0.236 |
|
1984 |
Chu E, Umetsu D, Yunis E, Geha RS. EBV transformed B cell lines present to antigen specific T cell clones determinants different from those recognized by antibody in an HLA-DR linked restricted fashion. Human Immunology. 8: 217-26. PMID 6196340 DOI: 10.1016/0198-8859(83)90039-3 |
0.236 |
|
1984 |
Chu E, Umetsu D, Lareau M, Schneeberger E, Geha RS. Analysis of antigen uptake and presentation by Epstein-Barr virus-transformed human lymphoblastoid B cells. European Journal of Immunology. 14: 291-8. PMID 6327319 DOI: 10.1002/eji.1830140403 |
0.235 |
|
2016 |
Janssen E, Tohme M, Hedayat M, Leick M, Kumari S, Ramesh N, Massaad MJ, Ullas S, Azcutia V, Goodnow CC, Randall KL, Qiao Q, Wu H, Al-Herz W, Cox D, ... ... Geha RS, et al. A DOCK8-WIP-WASp complex links T cell receptors to the actin cytoskeleton. The Journal of Clinical Investigation. PMID 27599296 DOI: 10.1172/Jci85774 |
0.235 |
|
2019 |
Lougaris V, Chou J, Beano A, Wallace JG, Baronio M, Gazzurelli L, Lorenzini T, Moratto D, Tabellini G, Parolini S, Seleman M, Stafstrom K, Xu H, Harris C, Geha RS, et al. A monoallelic activating mutation in RAC2 resulting in a combined immunodeficiency. The Journal of Allergy and Clinical Immunology. PMID 30654050 DOI: 10.1016/j.jaci.2019.01.001 |
0.235 |
|
1999 |
Ramesh N, Antón IM, Martínez-Quiles N, Geha RS. Waltzing with WASP. Trends in Cell Biology. 9: 15-9. PMID 10087612 DOI: 10.1016/S0962-8924(98)01411-1 |
0.235 |
|
2011 |
Massaad MJ, Ramesh N, Le Bras S, Giliani S, Notarangelo LD, Al-Herz W, Notarangelo LD, Geha RS. A peptide derived from the Wiskott-Aldrich syndrome (WAS) protein-interacting protein (WIP) restores WAS protein level and actin cytoskeleton reorganization in lymphocytes from patients with WAS mutations that disrupt WIP binding. The Journal of Allergy and Clinical Immunology. 127: 998-1005.e1-2. PMID 21376381 DOI: 10.1016/J.Jaci.2011.01.015 |
0.235 |
|
1995 |
Ramesh N, Morio T, Fuleihan R, Worm M, Horner A, Tsitsikov E, Castigli E, Geha RS. CD40-CD40 ligand (CD40L) interactions and X-linked hyperIgM syndrome (HIGMX-1). Clinical Immunology and Immunopathology. 76: S208-13. PMID 7554470 DOI: 10.1016/S0090-1229(95)90252-X |
0.235 |
|
2004 |
Kettner A, Kumar L, Antón IM, Sasahara Y, de la Fuente M, Pivniouk VI, Falet H, Hartwig JH, Geha RS. WIP regulates signaling via the high affinity receptor for immunoglobulin E in mast cells. The Journal of Experimental Medicine. 199: 357-68. PMID 14757742 DOI: 10.1084/jem.20030652 |
0.235 |
|
1993 |
Vercelli D, Geha RS. Regulation of IgE synthesis: from the membrane to the genes. Springer Seminars in Immunopathology. 15: 5-16. PMID 8362343 DOI: 10.1007/Bf00204622 |
0.234 |
|
1995 |
Fuleihan R, Ahern D, Geha RS. Expression of the CD40 ligand in T lymphocytes and induction of IgE isotype switching. International Archives of Allergy and Immunology. 107: 43-4. PMID 7542098 DOI: 10.1159/000236925 |
0.234 |
|
2003 |
Pivniouk VI, Snapper SB, Kettner A, Alenius H, Laouini D, Falet H, Hartwig J, Alt FW, Geha RS. Impaired signaling via the high-affinity IgE receptor in Wiskott-Aldrich syndrome protein-deficient mast cells. International Immunology. 15: 1431-40. PMID 14645152 DOI: 10.1093/Intimm/Dxg148 |
0.234 |
|
2005 |
Castigli E, Wilson SA, Scott S, Dedeoglu F, Xu S, Lam KP, Bram RJ, Jabara H, Geha RS. TACI and BAFF-R mediate isotype switching in B cells. The Journal of Experimental Medicine. 201: 35-9. PMID 15630136 DOI: 10.1084/jem.20032000 |
0.233 |
|
1989 |
Kisaki T, Leung DY, Jardieu P, Geha RS, Ishizaka K. Regulatory effects of human IgE-binding factors in the IgE synthesis by human and rat lymphocytes. European Journal of Immunology. 18: 1663-70. PMID 3264529 DOI: 10.1002/eji.1830181103 |
0.232 |
|
2020 |
Leyva-Castillo J, Daya M, Boorgula MP, Mathias R, Barnes K, Lai P, Petty C, Weller E, Harb H, Chatila T, Leung D, Phipatanakul W, Geha R. The IL-4Ra R576 polymorphism is associated with increased AD severity and promotes allergic skin inflammation. Journal of Allergy and Clinical Immunology. 145: AB239. DOI: 10.1016/J.Jaci.2019.12.133 |
0.232 |
|
2006 |
McDonald DR, Brown D, Bonilla FA, Geha RS. Interleukin receptor-associated kinase-4 deficiency impairs Toll-like receptor-dependent innate antiviral immune responses. The Journal of Allergy and Clinical Immunology. 118: 1357-62. PMID 17157666 DOI: 10.1016/j.jaci.2006.08.006 |
0.232 |
|
2011 |
Fried AJ, Rauter I, Dillon SR, Jabara HH, Geha RS. Functional analysis of transmembrane activator and calcium-modulating cyclophilin ligand interactor (TACI) mutations associated with common variable immunodeficiency. The Journal of Allergy and Clinical Immunology. 128: 226-228.e1. PMID 21419480 DOI: 10.1016/j.jaci.2011.01.048 |
0.231 |
|
2017 |
Archer N, Lee S, Ortines R, Wang Y, Liu H, Miller R, Dillen C, Marchitto M, Ashbaugh A, Uppal A, Cai S, Malhotra N, Oyoshi M, Geha R, Miller L. 643 An atopic dermatitis-like flare is mediated by dysbiosis and release of nuclear IL-1α from keratinocytes Journal of Investigative Dermatology. 137: S111. DOI: 10.1016/J.Jid.2017.02.665 |
0.231 |
|
2003 |
Kettner A, Pivniouk V, Kumar L, Falet H, Lee JS, Mulligan R, Geha RS. Structural requirements of SLP-76 in signaling via the high-affinity immunoglobulin E receptor (Fc epsilon RI) in mast cells. Molecular and Cellular Biology. 23: 2395-406. PMID 12640123 DOI: 10.1128/Mcb.23.7.2395-2406.2003 |
0.229 |
|
2014 |
Janssen E, Ozcan E, Liadaki K, Jabara HH, Manis J, Ullas S, Akira S, Fitzgerald KA, Golenbock DT, Geha RS. TRIF signaling is essential for TLR4-driven IgE class switching. Journal of Immunology (Baltimore, Md. : 1950). 192: 2651-8. PMID 24532577 DOI: 10.4049/Jimmunol.1300909 |
0.229 |
|
1985 |
Young MC, Harfi H, Sabbah R, Leung DY, Geha RS. A human T cell lymphoma secreting an immunoglobulin E specific helper factor Journal of Clinical Investigation. 75: 1977-1982. PMID 3159754 DOI: 10.1172/JCI111915 |
0.229 |
|
1980 |
Geha RS, Fruchter L, Borel Y. Hapten-specific T-cell unresponsiveness induced bybenzylpenicilloyl autologous gamma globulin conjugates in human lymphocyes in vitro. The Journal of Clinical Investigation. 65: 1509-14. PMID 6157701 DOI: 10.1172/JCI109816 |
0.228 |
|
2021 |
Bainter W, Lougaris V, Wallace JG, Badran Y, Hoyos-Bachiloglu R, Peters Z, Wilkie H, Das M, Janssen E, Beano A, Farhat KB, Kam C, Bercich L, Incardona P, Villanacci V, ... ... Geha RS, et al. Combined immunodeficiency with autoimmunity caused by a homozygous missense mutation in inhibitor of nuclear factor Science Immunology. 6: eabf6723. PMID 34533979 DOI: 10.1126/sciimmunol.abf6723 |
0.228 |
|
1996 |
Loh RK, Jabara HH, Geha RS. Mechanisms of inhibition of IgE synthesis by nedocromil sodium: nedocromil sodium inhibits deletional switch recombination in human B cells. The Journal of Allergy and Clinical Immunology. 97: 1141-50. PMID 8626993 DOI: 10.1016/S0091-6749(96)70269-5 |
0.227 |
|
1996 |
Castigli E, Young F, Carossino AM, Alt FW, Geha RS. CD40 expression and function in murine B cell ontogeny. International Immunology. 8: 405-411. PMID 8671627 DOI: 10.1093/Intimm/8.3.405 |
0.225 |
|
1976 |
Geha RS. Is the B-cell abnormality secondary to T-cell abnormality in severe combined immunodeficiency?1. Clinical Immunology and Immunopathology. 6: 102-6. PMID 780023 DOI: 10.1016/0090-1229(76)90065-9 |
0.225 |
|
2008 |
Benson MJ, Dillon SR, Castigli E, Geha RS, Xu S, Lam KP, Noelle RJ. Cutting edge: the dependence of plasma cells and independence of memory B cells on BAFF and APRIL. Journal of Immunology (Baltimore, Md. : 1950). 180: 3655-9. PMID 18322170 DOI: 10.4049/Jimmunol.180.6.3655 |
0.224 |
|
2003 |
Orange JS, Geha RS. Finding NEMO: Genetic disorders of NF-κB activation Journal of Clinical Investigation. 112: 983-985. PMID 14523034 DOI: 10.1172/Jci19960 |
0.224 |
|
2009 |
Oyoshi MK, Murphy GF, Geha RS. Filaggrin-deficient mice exhibit TH17-dominated skin inflammation and permissiveness to epicutaneous sensitization with protein antigen. The Journal of Allergy and Clinical Immunology. 124: 485-93, 493.e1. PMID 19665780 DOI: 10.1016/j.jaci.2009.05.042 |
0.224 |
|
2006 |
Elkhal A, Pichavant M, He R, Scott J, Meyer E, Goya S, Geha RS, Umetsu DT. CD1d restricted natural killer T cells are not required for allergic skin inflammation. The Journal of Allergy and Clinical Immunology. 118: 1363-8. PMID 17157667 DOI: 10.1016/j.jaci.2006.08.010 |
0.224 |
|
1996 |
Vercelli D, Jabara HH, Geha RS. Regulation of human IgE synthesis. International Reviews of Immunology. 5: 111-5. PMID 8691043 DOI: 10.3109/08830188909061977 |
0.224 |
|
2000 |
Mehlhop PD, van de Rijn M, Brewer JP, Kisselgof AB, Geha RS, Oettgen HC, Martin TR. CD40L, but not CD40, is required for allergen-induced bronchial hyperresponsiveness in mice. American Journal of Respiratory Cell and Molecular Biology. 23: 646-51. PMID 11062143 DOI: 10.1165/AJRCMB.23.5.3954 |
0.223 |
|
1996 |
Tsytsykova AV, Tsitsikov EN, Geha RS. The CD40L promoter contains nuclear factor of activated T cells-binding motifs which require AP-1 binding for activation of transcription. The Journal of Biological Chemistry. 271: 3763-70. PMID 8631992 DOI: 10.1074/jbc.271.7.3763 |
0.222 |
|
2017 |
Alroqi FJ, Charbonnier LM, Keles S, Ghandour F, Mouawad P, Sabouneh R, Mohammed R, Almutairi A, Chou J, Massaad MJ, Geha RS, Baz Z, Chatila TA. DOCK8 Deficiency Presenting as an IPEX-Like Disorder. Journal of Clinical Immunology. PMID 29058101 DOI: 10.1007/S10875-017-0451-1 |
0.222 |
|
1985 |
Geha R, Ambrosino D, Siber G, Martin P, Howie G, Umetsu D. 336 Children with IgG2 subclass deficiency have an impaired response to the polyribose phosphate (PRP) polysaccharide vaccine The Journal of Allergy and Clinical Immunology. 75: 188. DOI: 10.1016/0091-6749(85)90471-3 |
0.222 |
|
2000 |
Bonilla FA, Fujita RM, Pivniouk VI, Chan AC, Geha RS. Adapter proteins SLP-76 and BLNK both are expressed by murine macrophages and are linked to signaling via Fcgamma receptors I and II/III. Proceedings of the National Academy of Sciences of the United States of America. 97: 1725-30. PMID 10677525 DOI: 10.1073/pnas.040543597 |
0.22 |
|
1985 |
UMETSU D, LEUNG D, JABARA H, GEHA R. 135 Monoclonal helper T cells induce normal B cells to synthesize IgE antibody Journal of Allergy and Clinical Immunology. 75: 138. DOI: 10.1016/0091-6749(85)90270-2 |
0.22 |
|
2001 |
Dunn IF, Sannikova TY, Geha RS, Tsitsikov EN. Identification and characterization of two CD40-inducible enhancers in the mouse TRAF1 gene locus. Molecular Immunology. 37: 961-73. PMID 11395135 DOI: 10.1016/S0161-5890(01)00015-3 |
0.219 |
|
1994 |
Fuleihan R, Ahern D, Geha RS. Decreased expression of the ligand for CD40 in newborn lymphocytes. European Journal of Immunology. 24: 1925-8. PMID 7914491 DOI: 10.1002/eji.1830240832 |
0.219 |
|
2023 |
Fiskin E, Eraslan G, Alora-Palli MB, Leyva-Castillo JM, Kim S, Choe H, Lareau CA, Lau H, Finan EP, Teixeira-Soldano I, LaBere B, Chu A, Woods B, Chou J, Slyper M, ... ... Geha R, et al. Multi-modal skin atlas identifies a multicellular immune-stromal community associated with altered cornification and specific T cell expansion in atopic dermatitis. Biorxiv : the Preprint Server For Biology. PMID 37961084 DOI: 10.1101/2023.10.29.563503 |
0.219 |
|
2006 |
Gallego MD, de la Fuente MA, Anton IM, Snapper S, Fuhlbrigge R, Geha RS. WIP and WASP play complementary roles in T cell homing and chemotaxis to SDF-1alpha. International Immunology. 18: 221-32. PMID 16141245 DOI: 10.1093/intimm/dxh310 |
0.218 |
|
1991 |
Jabara HH, Fu SM, Geha RS, Vercelli D. CD40 and IgE: synergism between anti-CD40 monoclonal antibody and interleukin 4 in the induction of IgE synthesis by highly purified human B cells. The Journal of Experimental Medicine. 172: 1861-4. PMID 1701824 DOI: 10.1084/Jem.172.6.1861 |
0.218 |
|
2003 |
Brodeur SR, Angelini F, Bacharier LB, Blom AM, Mizoguchi E, Fujiwara H, Plebani A, Notarangelo LD, Dahlback B, Tsitsikov E, Geha RS. C4b-binding protein (C4BP) activates B cells through the CD40 receptor. Immunity. 18: 837-48. PMID 12818164 DOI: 10.1016/S1074-7613(03)00149-3 |
0.218 |
|
2016 |
Platt CD, Massaad MJ, Cangemi B, Schmidt B, Aldhekri H, Geha RS. JAK3 deficiency caused by a homozygous synonymous exonic mutation that creates a dominant splice site. The Journal of Allergy and Clinical Immunology. PMID 27956217 DOI: 10.1016/J.Jaci.2016.09.057 |
0.218 |
|
1987 |
Leung DY, Burns JC, Newburger JW, Geha RS. Reversal of lymphocyte activation in vivo in the Kawasaki syndrome by intravenous gammaglobulin. The Journal of Clinical Investigation. 79: 468-72. PMID 2433307 DOI: 10.1172/Jci112835 |
0.217 |
|
1992 |
Chatila T, Scholl P, Spertini F, Ramesh N, Trede N, Fuleihan R, Geha RS. Toxic shock syndrome toxin-1, toxic shock, and the immune system. Current Topics in Microbiology and Immunology. 174: 63-79. PMID 1802619 DOI: 10.1007/978-3-642-50998-8_5 |
0.217 |
|
2020 |
Lee PY, Kellner ES, Huang Y, Furutani E, Huang Z, Bainter W, Alosaimi MF, Stafstrom K, Platt CD, Stauber T, Raz S, Tirosh I, Weiss A, Jordan MB, Krupski C, ... ... Geha RS, et al. Genotype and functional correlates of disease phenotype in deficiency of adenosine deaminase 2 (DADA2). The Journal of Allergy and Clinical Immunology. PMID 31945408 DOI: 10.1016/J.Jaci.2019.12.908 |
0.217 |
|
1984 |
Young MC, Leung DYM, Geha RS. Production of IgE-potentiating factor in man by T cell lines bearing Fc receptors for IgE European Journal of Immunology. 14: 871-878. PMID 6237918 DOI: 10.1002/eji.1830141003 |
0.217 |
|
1987 |
Geha RS. Regulation of IgE synthesis in man. New England and Regional Allergy Proceedings. 6: 170-3. PMID 2957582 DOI: 10.2500/108854185779045161 |
0.217 |
|
2011 |
Oyoshi MK, Elkhal A, Scott JE, Wurbel MA, Hornick JL, Campbell JJ, Geha RS. Epicutaneous challenge of orally immunized mice redirects antigen-specific gut-homing T cells to the skin. The Journal of Clinical Investigation. 121: 2210-20. PMID 21537081 DOI: 10.1172/JCI43586 |
0.217 |
|
1981 |
Geha RS, Reinherz E, Leung D, McKee KT, Schlossman S, Rosen FS. Deficiency of suppressor T cells in the hyperimmunoglobulin E syndrome. The Journal of Clinical Investigation. 68: 783-91. PMID 6456275 DOI: 10.1172/JCI110315 |
0.217 |
|
1985 |
Chu E, Gesner M, Gorga J, Geha RS. Role of Ia antigens and interleukin 1 in T-cell proliferation to phytohemagglutinin. Clinical Immunology and Immunopathology. 36: 70-80. PMID 2988840 DOI: 10.1016/0090-1229(85)90040-6 |
0.216 |
|
1987 |
Umetsu DT, Katzen D, Chatila T, Miller R, Jabara HH, Maher M, Oettgen H, Terhorst C, Geha RS. Requirements for activation of human peripheral blood T cells by mouse monoclonal antibodies to CD3. Clinical Immunology and Immunopathology. 43: 48-64. PMID 3103959 DOI: 10.1016/0090-1229(87)90156-5 |
0.216 |
|
1997 |
Tsitsikov EN, Wright DA, Geha RS. CD30 induction of human immunodeficiency virus gene transcription is mediated by TRAF2. Proceedings of the National Academy of Sciences of the United States of America. 94: 1390-5. PMID 9037063 DOI: 10.1073/pnas.94.4.1390 |
0.215 |
|
1995 |
Castigli E, Fuleihan R, Ramesh N, Tsitsikov E, Tsytsykova A, Geha RS. CD40 ligand/CD40 deficiency. International Archives of Allergy and Immunology. 107: 37-9. PMID 7542090 DOI: 10.1159/000236923 |
0.215 |
|
1983 |
Saryan JA, Rappeport J, Leung DY, Parkman R, Geha RS. Regulation of human immunoglobulin E synthesis in acute graft versus host disease. The Journal of Clinical Investigation. 71: 556-64. PMID 6338041 DOI: 10.1172/JCI110800 |
0.215 |
|
2012 |
Alangari A, Alsultan A, Adly N, Massaad MJ, Kiani IS, Aljebreen A, Raddaoui E, Almomen AK, Al-Muhsen S, Geha RS, Alkuraya FS. LPS-responsive beige-like anchor (LRBA) gene mutation in a family with inflammatory bowel disease and combined immunodeficiency. The Journal of Allergy and Clinical Immunology. 130: 481-8.e2. PMID 22721650 DOI: 10.1016/J.Jaci.2012.05.043 |
0.215 |
|
2015 |
Chou J, Massaad MJ, Cangemi B, Bainter W, Platt C, Badran YR, Raphael BP, Kamin DS, Goldsmith JD, Pai SY, Al-Herz W, Geha RS. A novel mutation in ICOS presenting as hypogammaglobulinemia with susceptibility to opportunistic pathogens. The Journal of Allergy and Clinical Immunology. 136: 794-797.e1. PMID 25678089 DOI: 10.1016/J.Jaci.2014.12.1940 |
0.214 |
|
2020 |
Wilkie H, Janssen E, Leyva-Castillo JM, Geha RS. DOCK8 expression in Treg cells maintains their stability and limits contact hypersensitivity. The Journal of Investigative Dermatology. PMID 33171169 DOI: 10.1016/j.jid.2020.09.027 |
0.213 |
|
1996 |
Fuleihan R, Ramesh N, Geha RS. X-linked agammaglobulinemia and immunoglobulin deficiency with normal or elevated IgM: immunodeficiencies of B cell development and differentiation. Advances in Immunology. 60: 37-56. PMID 8607374 DOI: 10.1016/S0065-2776(08)60583-0 |
0.212 |
|
1990 |
Chatila T, Castigli E, Pahwa R, Pahwa S, Chirmule N, Oyaizu N, Good RA, Geha RS. Primary combined immunodeficiency resulting from defective transcription of multiple T-cell lymphokine genes. Proceedings of the National Academy of Sciences of the United States of America. 87: 10033-7. PMID 2263604 DOI: 10.1073/pnas.87.24.10033 |
0.212 |
|
1986 |
Young M, Geha RS. Human regulatory T-cell subsets. Annual Review of Medicine. 37: 165-72. PMID 2939789 DOI: 10.1146/annurev.me.37.020186.001121 |
0.211 |
|
1998 |
Ramesh N, Antón IM, Hartwig JH, Geha RS. WIP, a protein associated with wiskott-aldrich syndrome protein, induces actin polymerization and redistribution in lymphoid cells. Proceedings of the National Academy of Sciences of the United States of America. 94: 14671-6. PMID 9405671 DOI: 10.1073/PNAS.94.26.14671 |
0.211 |
|
2000 |
Bacharier LB, Geha RS. Molecular mechanisms of IgE regulation. The Journal of Allergy and Clinical Immunology. 105: S547-58. PMID 10669540 DOI: 10.1016/S0091-6749(00)90059-9 |
0.211 |
|
2015 |
Engelhardt KR, Gertz ME, Keles S, Schäffer AA, Sigmund EC, Glocker C, Saghafi S, Pourpak Z, Ceja R, Sassi A, Graham LE, Massaad MJ, Mellouli F, Ben-Mustapha I, Khemiri M, ... ... Geha RS, et al. The extended clinical phenotype of 64 patients with dedicator of cytokinesis 8 deficiency. The Journal of Allergy and Clinical Immunology. PMID 25724123 DOI: 10.1016/J.Jaci.2014.12.1945 |
0.21 |
|
2014 |
Massaad MJ, Oyoshi MK, Kane J, Koduru S, Alcaide P, Nakamura F, Ramesh N, Luscinskas FW, Hartwig J, Geha RS. Binding of WIP to actin is essential for T cell actin cytoskeleton integrity and tissue homing. Molecular and Cellular Biology. 34: 4343-54. PMID 25246631 DOI: 10.1128/Mcb.00533-14 |
0.209 |
|
1983 |
Leung DY, Bhan AK, Schneeberger EE, Geha RS. Characterization of the mononuclear cell infiltrate in atopic dermatitis using monoclonal antibodies. The Journal of Allergy and Clinical Immunology. 71: 47-56. PMID 6337197 DOI: 10.1016/0091-6749(83)90546-8 |
0.209 |
|
2015 |
Sobh A, Crestani E, Cangemi B, Kane J, Chou J, Pai SY, Notarangelo LD, El-Herz W, Geha RS, Massaad MJ. Autoimmune lymphoproliferative syndrome caused by a homozygous FasL mutation that disrupts FasL assembly. The Journal of Allergy and Clinical Immunology. PMID 26456038 DOI: 10.1016/J.Jaci.2015.08.025 |
0.209 |
|
1995 |
Ren CL, Fu SM, Geha RS. Protein tyrosine kinase activation and protein kinase C translocation are functional components of CD40 signal transduction in resting human B cells. Immunological Investigations. 23: 437-48. PMID 7531671 DOI: 10.3109/08820139409066838 |
0.209 |
|
1990 |
Vercelli D, Jabara HH, Cunningham-Rundles C, Abrams JS, Lewis DB, Meyer J, Schneider LC, Leung DYM, Geha RS. Regulation of immunoglobulin (Ig)E synthesis in the Hyper-IgE syndrome Journal of Clinical Investigation. 85: 1666-1671. PMID 2110192 DOI: 10.1172/Jci114618 |
0.209 |
|
1979 |
Geha RS. Regulation of human B cell activation. Immunological Reviews. 45: 275-305. PMID 89730 DOI: 10.1111/j.1600-065X.1979.tb00281.x |
0.208 |
|
2019 |
Calzoni E, Platt CD, Keles S, Kuehn HS, Beaussant-Cohen S, Zhang Y, Pazmandi J, Lanzi G, Pala F, Tahiat A, Artac H, Heredia RJ, Dmytrus J, Reisli I, Uygun V, ... ... Geha RS, et al. F-BAR domain only protein 1 (FCHO1) deficiency is a novel cause of combined immune deficiency in humans. The Journal of Allergy and Clinical Immunology. PMID 30822429 DOI: 10.1016/J.Jaci.2019.02.014 |
0.208 |
|
2014 |
Geha RS, Rosen FS. Immunoregulatory T-cell defects. Immunology Today. 4: 233-6. PMID 25290118 DOI: 10.1016/0167-5699(83)90034-8 |
0.208 |
|
2006 |
Bryce PJ, Mathias CB, Harrison KL, Watanabe T, Geha RS, Oettgen HC. The H1 histamine receptor regulates allergic lung responses. The Journal of Clinical Investigation. 116: 1624-32. PMID 16680192 DOI: 10.1172/JCI26150 |
0.208 |
|
1983 |
Chu E, Umetsu D, Rosen F, Geha RS. Major histocompatibility restriction of antigen recognition by T cells in a recipient of haplotype mismatched human bone marrow transplantation. The Journal of Clinical Investigation. 72: 1124-9. PMID 6193142 DOI: 10.1172/JCI111037 |
0.208 |
|
1986 |
Leung DYM, Collins T, Lapierre LA, Geha RS, Pober JS. Immunoglobulin M antibodies present in the acute phase of Kawasaki syndrome lyse cultured vascular endothelial cells stimulated by gamma interferon Journal of Clinical Investigation. 77: 1428-1435. PMID 3084559 DOI: 10.1172/Jci112454 |
0.207 |
|
1985 |
Umetsu DT, Pober JS, Jabara HH, Fiers W, Yunis EJ, Burakoff SJ, Reiss CS, Geha RS. Human dermal fibroblasts present tetanus toxoid antigen to antigen-specific T cell clones. The Journal of Clinical Investigation. 76: 254-60. PMID 3160726 DOI: 10.1172/Jci111955 |
0.207 |
|
1986 |
Burns JC, Geha RS, Schneeberger EE, Newburger JW, Rosen FS, Glezen LS, Huang AS, Natale J, Leung DY. Polymerase activity in lymphocyte culture supernatants from patients with Kawasaki disease. Nature. 323: 814-6. PMID 2430187 DOI: 10.1038/323814A0 |
0.207 |
|
1990 |
Mourad W, Geha RS, Chatila T. Engagement of major histocompatibility complex class II molecules induces sustained, lymphocyte function-associated molecule 1-dependent cell adhesion Journal of Experimental Medicine. 172: 1513-1516. PMID 2230655 DOI: 10.1084/Jem.172.5.1513 |
0.205 |
|
2018 |
Malhotra N, Leyva-Castillo JM, Jadhav U, Barreiro O, Kam C, O'Neill NK, Meylan F, Chambon P, von Andrian UH, Siegel RM, Wang EC, Shivdasani R, Geha RS. RORα-expressing T regulatory cells restrain allergic skin inflammation. Science Immunology. 3. PMID 29500225 DOI: 10.1126/Sciimmunol.Aao6923 |
0.205 |
|
1993 |
Geha R, Buckley CE, Greenberger P, Patterson R, Polmar S, Saxon A, Rohr A, Yang W, Drouin M. Aspartame is no more likely than placebo to cause urticaria/angioedema: Results of a multicenter, randomized, double-blind, placebo-controlled, crossover study The Journal of Allergy and Clinical Immunology. 92: 513-520. PMID 8409113 DOI: 10.1016/0091-6749(93)90075-Q |
0.205 |
|
2004 |
Vivarelli MS, McDonald D, Miller M, Cusson N, Kelliher M, Geha RS. RIP links TLR4 to Akt and is essential for cell survival in response to LPS stimulation. The Journal of Experimental Medicine. 200: 399-404. PMID 15280422 DOI: 10.1084/jem.20040446 |
0.205 |
|
2020 |
Harb H, Stephen-Victor E, Crestani E, Benamar M, Massoud A, Cui Y, Charbonnier LM, Arbag S, Baris S, Cunnigham A, Leyva-Castillo JM, Geha RS, Mousavi AJ, Guennewig B, Schmitz-Abe K, et al. A regulatory T cell Notch4-GDF15 axis licenses tissue inflammation in asthma. Nature Immunology. PMID 32929274 DOI: 10.1038/S41590-020-0777-3 |
0.204 |
|
2018 |
Biswas A, Shouval DS, Griffith A, Goettel JA, Field M, Kang YH, Konnikova L, Janssen E, Redhu NS, Thrasher AJ, Chatila T, Kuchroo VK, Geha RS, Notarangelo LD, Pai SY, et al. WASP-mediated regulation of anti-inflammatory macrophages is IL-10 dependent and is critical for intestinal homeostasis. Nature Communications. 9: 1779. PMID 29725003 DOI: 10.1038/S41467-018-03670-6 |
0.204 |
|
2002 |
Sasahara Y, Rachid R, Byrne MJ, de la Fuente MA, Abraham RT, Ramesh N, Geha RS. Mechanism of recruitment of WASP to the immunological synapse and of its activation following TCR ligation. Molecular Cell. 10: 1269-81. PMID 12504004 DOI: 10.1016/S1097-2765(02)00728-1 |
0.204 |
|
2019 |
Chou J, Alazami AM, Jaber F, Hoyos-Bachiloglu R, Jones J, Weeks S, Alosaimi MF, Bainter W, Cangemi B, Badran YR, Mohammed R, Alroqi F, Almutairi A, Al-Onazi N, AlAjaji S, ... ... Geha RS, et al. Hypomorphic variants in AK2 reveal the contribution of mitochondrial function to B cell activation. The Journal of Allergy and Clinical Immunology. PMID 31862378 DOI: 10.1016/J.Jaci.2019.12.004 |
0.203 |
|
2004 |
Dedeoglu F, Horwitz B, Chaudhuri J, Alt FW, Geha RS. Induction of activation-induced cytidine deaminase gene expression by IL-4 and CD40 ligation is dependent on STAT6 and NFkappaB. International Immunology. 16: 395-404. PMID 14978013 DOI: 10.1093/Intimm/Dxh042 |
0.203 |
|
2018 |
Hoff S, Oyoshi MK, Hornick JL, Geha RS. MyD88 signaling in T regulatory cells by endogenous ligands dampens skin inflammation in filaggrin deficient mice. Clinical Immunology (Orlando, Fla.). 195: 88-92. PMID 30099194 DOI: 10.1016/j.clim.2018.08.001 |
0.202 |
|
2001 |
Celestin J, Rotschke O, Falk K, Ramesh N, Jabara H, Strominger J, Geha RS. IL-3 induces B7.2 (CD86) expression and costimulatory activity in human eosinophils Journal of Immunology. 167: 6097-6104. PMID 11714768 DOI: 10.4049/Jimmunol.167.11.6097 |
0.202 |
|
2020 |
Leyva-Castillo JM, Jabara HH, Wenzel J, McGurk A, Wong D, Bieber T, Geha RS. APRIL expression is upregulated in atopic dermatitis skin lesions and at sites of antigen driven allergic skin inflammation in mice. Clinical Immunology (Orlando, Fla.). 108556. PMID 32777271 DOI: 10.1016/j.clim.2020.108556 |
0.201 |
|
1998 |
Worm MM, Tsytsykova A, Geha RS. CD40 ligation and IL-4 use different mechanisms of transcriptional activation of the human lymphotoxin alpha promoter in B cells. European Journal of Immunology. 28: 901-6. PMID 9541585 DOI: 10.1002/(SICI)1521-4141(199803)28:03<901::AID-IMMU901>3.0.CO;2-S |
0.201 |
|
1979 |
Geha RS, Milgrom H, Broff M, Alpert S, Martin S, Yunis EJ. Effect of anti-HLA antisera on macrophage-T-cell interactions. Proceedings of the National Academy of Sciences of the United States of America. 76: 4038-41. PMID 115010 DOI: 10.1073/pnas.76.8.4038 |
0.201 |
|
2002 |
Ma W, Bryce PJ, Humbles AA, Laouini D, Yalcindag A, Alenius H, Friend DS, Oettgen HC, Gerard C, Geha RS. CCR3 is essential for skin eosinophilia and airway hyperresponsiveness in a murine model of allergic skin inflammation. The Journal of Clinical Investigation. 109: 621-8. PMID 11877470 DOI: 10.1172/Jci14097 |
0.2 |
|
2019 |
Wallace JG, Zambrano-Rodas P, Córdova-Calderón W, Estrada-Turriate S, Mendoza-Quispe D, Ontiveros YL, Geha RS, Chou J, Platt CD. Dysregulated actin dynamics in activated PI3Kδ syndrome. Clinical Immunology (Orlando, Fla.). 108311. PMID 31760094 DOI: 10.1016/J.Clim.2019.108311 |
0.2 |
|
2017 |
Al-Herz W, Massaad MJ, Chou J, Notarangelo LD, Geha RS. DNA recombination defects in Kuwait: Clinical, immunologic and genetic profile. Clinical Immunology (Orlando, Fla.). PMID 29051008 DOI: 10.1016/J.Clim.2017.10.006 |
0.199 |
|
1984 |
Leung DY, Brozek C, Frankel R, Geha RS. IgE-specific suppressor factors in normal human serum. Clinical Immunology and Immunopathology. 32: 339-50. PMID 6467688 DOI: 10.1016/0090-1229(84)90277-0 |
0.199 |
|
2016 |
Yu H, Zhang VW, Stray-Pedersen A, Hanson IC, Forbes LR, de la Morena MT, Chinn IK, Gorman E, Mendelsohn NJ, Pozos T, Wiszniewski W, Nicholas SK, Yates AB, Moore LE, Berge KE, ... ... Geha RS, et al. Rapid molecular diagnostics of severe primary immunodeficiency determined by using targeted next-generation sequencing. The Journal of Allergy and Clinical Immunology. PMID 27484032 DOI: 10.1016/J.Jaci.2016.05.035 |
0.199 |
|
1979 |
Fineman SM, Rosen FS, Geha RS. Transient hypogammaglobulinemia, elevated immunoglobulin E levels, and food allergy. The Journal of Allergy and Clinical Immunology. 64: 216-22. PMID 89129 DOI: 10.1016/0091-6749(79)90098-8 |
0.199 |
|
2005 |
Jabara HH, Geha RS. Jun N-terminal kinase is essential for CD40-mediated IgE class switching in B cells. The Journal of Allergy and Clinical Immunology. 115: 856-63. PMID 15806010 DOI: 10.1016/j.jaci.2005.01.020 |
0.198 |
|
1981 |
Broff MD, Jonsen ME, Geha RS. Nature of the immunogenic moiety recognized by the human T cell proliferating in response to tetanus toxoid antigen. European Journal of Immunology. 11: 365-71. PMID 6973474 DOI: 10.1002/eji.1830110504 |
0.198 |
|
2002 |
Jabara H, Laouini D, Tsitsikov E, Mizoguchi E, Bhan A, Castigli E, Dedeoglu F, Pivniouk V, Brodeur S, Geha R. The binding site for TRAF2 and TRAF3 but not for TRAF6 is essential for CD40-mediated immunoglobulin class switching. Immunity. 17: 265-76. PMID 12354380 DOI: 10.1016/S1074-7613(02)00394-1 |
0.197 |
|
2008 |
Jabara HH, Chaudhuri J, Dutt S, Dedeoglu F, Weng Y, Murphy MM, Franco S, Alt FW, Manis J, Geha RS. B-cell receptor cross-linking delays activation-induced cytidine deaminase induction and inhibits class-switch recombination to IgE. The Journal of Allergy and Clinical Immunology. 121: 191-196.e2. PMID 17900678 DOI: 10.1016/j.jaci.2007.08.008 |
0.197 |
|
1991 |
Spertini F, Spits H, Geha RS. Staphylococcal exotoxins deliver activation signals to human T-cell clones via major histocompatibility complex class II molecules. Proceedings of the National Academy of Sciences of the United States of America. 88: 7533-7. PMID 1881894 DOI: 10.1073/pnas.88.17.7533 |
0.196 |
|
2007 |
Geha RS, Notarangelo LD, Casanova JL, Chapel H, Conley ME, Fischer A, Hammarström L, Nonoyama S, Ochs HD, Puck JM, Roifman C, Seger R, Wedgwood J. Primary immunodeficiency diseases: an update from the International Union of Immunological Societies Primary Immunodeficiency Diseases Classification Committee. The Journal of Allergy and Clinical Immunology. 120: 776-94. PMID 17952897 DOI: 10.1016/j.jaci.2007.08.053 |
0.196 |
|
1993 |
Castigli E, Pahwa R, Good RA, Geha RS, Chatila TA. Molecular basis of a multiple lymphokine deficiency in a patient with severe combined immunodeficiency. Proceedings of the National Academy of Sciences of the United States of America. 90: 4728-32. PMID 8506326 DOI: 10.1073/pnas.90.10.4728 |
0.196 |
|
2010 |
McDonald DR, Goldman F, Gomez-Duarte OD, Issekutz AC, Kumararatne DS, Doffinger R, Geha RS. Impaired T-cell receptor activation in IL-1 receptor-associated kinase-4-deficient patients. The Journal of Allergy and Clinical Immunology. 126: 332-7, 337.e1-2. PMID 20621347 DOI: 10.1016/j.jaci.2010.05.013 |
0.196 |
|
1997 |
Bonilla FA, Kokron CM, Swinton P, Geha RS. Targeted gene disruption of murine CD7. International Immunology. 9: 1875-83. PMID 9466315 DOI: 10.1093/intimm/9.12.1875 |
0.195 |
|
2014 |
Jing H, Zhang Q, Zhang Y, Hill BJ, Dove CG, Gelfand EW, Atkinson TP, Uzel G, Matthews HF, Mustillo PJ, Lewis DB, Kavadas FD, Hanson IC, Kumar AR, Geha RS, et al. Somatic reversion in dedicator of cytokinesis 8 immunodeficiency modulates disease phenotype. The Journal of Allergy and Clinical Immunology. 133: 1667-75. PMID 24797421 DOI: 10.1016/j.jaci.2014.03.025 |
0.195 |
|
1994 |
Scholl PR, Geha RS. MHC class II signaling in B-cell activation. Immunology Today. 15: 418-22. PMID 7524519 DOI: 10.1016/0167-5699(94)90271-2 |
0.195 |
|
1997 |
Tsitsikov EN, Gutierrez-Ramos JC, Geha RS. Impaired CD19 expression and signaling, enhanced antibody response to type II T independent antigen and reduction of B-1 cells in CD81-deficient mice. Proceedings of the National Academy of Sciences of the United States of America. 94: 10844-9. PMID 9380722 DOI: 10.1073/PNAS.94.20.10844 |
0.194 |
|
1983 |
Leung DY, Saryan JA, Frankel R, Lareau M, Geha RS. Impairment of the autologous mixed lymphocyte reaction in atopic dermatitis. The Journal of Clinical Investigation. 72: 1482-6. PMID 6226679 DOI: 10.1172/JCI111104 |
0.193 |
|
2021 |
Platt JL, de Mattos Barbosa MG, Huynh D, Lefferts AR, Katta J, Kharas C, Freddolino PL, Bassis CM, Wobus CE, Geha R, Bram RJ, Nunez G, Kamada N, Cascalho M. TNFRSF13B polymorphisms counteract microbial adaptation to natural IgA. Jci Insight. PMID 34111031 DOI: 10.1172/jci.insight.148208 |
0.193 |
|
1981 |
Geha RS, Mudawwar F, Rosen FS, Siegel RL. 915 DEFICIENCY OF HELPER T CELLS IN TRANSIENT HYPOGAMMA-GLOBULINEMIA Pediatric Research. 15: 595-595. DOI: 10.1203/00006450-198104001-00940 |
0.193 |
|
2010 |
He R, Oyoshi MK, Wang JY, Hodge MR, Jin H, Geha RS. The prostaglandin D₂ receptor CRTH2 is important for allergic skin inflammation after epicutaneous antigen challenge. The Journal of Allergy and Clinical Immunology. 126: 784-90. PMID 20713302 DOI: 10.1016/j.jaci.2010.07.006 |
0.192 |
|
1978 |
Mudawwar FB, Yunis EJ, Geha RS. Antigen-specific helper factor in man. The Journal of Experimental Medicine. 148: 1032-43. PMID 359749 DOI: 10.1084/jem.148.4.1032 |
0.191 |
|
1995 |
Castigli E, Irani AM, Geha RS, Chatila T. Defective expression of early activation genes in cartilage-hair hypoplasia (CHH) with severe combined immunodeficiency (SCID). Clinical and Experimental Immunology. 102: 6-10. PMID 7554401 DOI: 10.1111/j.1365-2249.1995.tb06628.x |
0.191 |
|
2014 |
Platt C, Geha RS, Chou J. Gene hunting in the genomic era: Approaches to diagnostic dilemmas in patients with primary immunodeficiencies Journal of Allergy and Clinical Immunology. 134: 262-268. PMID 24100122 DOI: 10.1016/J.Jaci.2013.08.021 |
0.191 |
|
2009 |
Jabara HH, Weng Y, Sannikova T, Geha RS. TRAF2 and TRAF3 independently mediate Ig class switching driven by CD40. International Immunology. 21: 477-88. PMID 19228877 DOI: 10.1093/intimm/dxp013 |
0.191 |
|
2008 |
Hidano S, Sasanuma H, Ohshima K, Seino K, Kumar L, Hayashi K, Hikida M, Kurosaki T, Taniguchi M, Geha RS, Kitamura D, Goitsuka R. Distinct regulatory functions of SLP-76 and MIST in NK cell cytotoxicity and IFN-gamma production. International Immunology. 20: 345-52. PMID 18203684 DOI: 10.1093/intimm/dxm150 |
0.191 |
|
1982 |
Alpert SD, Jonsen ME, Broff MD, Schneeberger E, Geha RS. Macrophage T-cell interaction in man: handling of tetanus toxoid antigen by human monocytes. Journal of Clinical Immunology. 1: 21-9. PMID 6977550 DOI: 10.1007/BF00915473 |
0.191 |
|
1994 |
Fuleihan R, Ramesh N, Horner A, Ahern D, Belshaw PJ, Alberg DG, Stamenkovic I, Harmon W, Geha RS. Cyclosporin A inhibits CD40 ligand expression in T lymphocytes. The Journal of Clinical Investigation. 93: 1315-20. PMID 7907604 DOI: 10.1172/JCI117089 |
0.19 |
|
1994 |
Loh RK, Jabara HH, Ren CL, Fu SM, Geha RS. Role of protein tyrosine kinases in CD40/interleukin-4-mediated isotype switching to IgE. The Journal of Allergy and Clinical Immunology. 94: 784-92. PMID 7523475 DOI: 10.1016/0091-6749(94)90187-2 |
0.189 |
|
1986 |
Leung DY, Frankel R, Wood N, Geha RS. Potentiation of human immunoglobulin E synthesis by plasma immunoglobulin E binding factors from patients with the hyperimmunoglobulin E syndrome. The Journal of Clinical Investigation. 77: 952-7. PMID 3485112 DOI: 10.1172/JCI112395 |
0.189 |
|
1991 |
IABARA H, FU S, GEHA R, VERCELLI D. 417 Engagement of CD40 in the presence of rIL-4 induces IgE synthesis by highly purified human B cells Journal of Allergy and Clinical Immunology. 87: 244. DOI: 10.1016/0091-6749(91)91700-4 |
0.189 |
|
1985 |
Geha RS, Quinti I, Austen KF, Cicardi M, Sheffer A, Rosen FS. Acquired C1-inhibitor deficiency associated with antiidiotypic antibody to monoclonal immunoglobulins. The New England Journal of Medicine. 312: 534-40. PMID 3918266 DOI: 10.1056/NEJM198502283120902 |
0.189 |
|
1975 |
Geha RS, Colten HR, Schneeberger E, Merler E. Cooperation between human thymus-derived and bone marrow-derived lymphocytes in the antibody response to ragweed antigen E in vitro. The Journal of Clinical Investigation. 56: 386-90. PMID 50327 DOI: 10.1172/JCI108103 |
0.188 |
|
2018 |
Al-Herz W, Chou J, Delmonte OM, Massaad MJ, Bainter W, Castagnoli R, Klein C, Bryceson YT, Geha RS, Notarangelo LD. Comprehensive Genetic Results for Primary Immunodeficiency Disorders in a Highly Consanguineous Population. Frontiers in Immunology. 9: 3146. PMID 30697212 DOI: 10.3389/Fimmu.2018.03146 |
0.188 |
|
1984 |
Chu ET, Rosenwasser LJ, Dinarello CA, Rosen FS, Geha RS. Immunodeficiency with defective T-cell response to interleukin 1. Proceedings of the National Academy of Sciences of the United States of America. 81: 4945-9. PMID 6611555 DOI: 10.1073/pnas.81.15.4945 |
0.185 |
|
1995 |
Ramesh N, Horner A, Ahern D, Geha RS. Bacterial superantigens induce the proliferation of resting gamma/delta receptor bearing T cells. Immunological Investigations. 24: 713-24. PMID 8543336 DOI: 10.3109/08820139509060700 |
0.185 |
|
1982 |
Issekutz T, Jebara H, Geha RS. Induction of proliferation of human T cells and T-cell blasts by monocyte-derived factors and lectin. Clinical Immunology and Immunopathology. 23: 634-47. PMID 6981478 DOI: 10.1016/0090-1229(82)90326-9 |
0.185 |
|
1991 |
Geha RS, Castigli E, Chatila T. Novel immune deficiencies: defective transcription of lymphokine genes. Clinical and Experimental Allergy : Journal of the British Society For Allergy and Clinical Immunology. 190-4. PMID 2032144 DOI: 10.1111/j.1365-2222.1991.tb01726.x |
0.185 |
|
1989 |
Vercelli D, Leung DY, Jabara HH, Geha RS. Interleukin 4 dependent induction of IgE synthesis and CD23 expression by the supernatants of a human helper T cell clone. International Archives of Allergy and Applied Immunology. 88: 119-21. PMID 2523353 DOI: 10.1159/000234761 |
0.184 |
|
1994 |
Fuleihan R, Trede N, Chatila T, Geha RS. Superantigens activate HIV-1 gene expression in monocytic cells. Clinical Immunology and Immunopathology. 72: 357-61. PMID 8062448 DOI: 10.1006/Clin.1994.1153 |
0.184 |
|
1995 |
Insel RA, Varade WS, Chu YW, Marin E, Fuleihan R, Geha RS. Somatic mutation of human immunoglobulin V genes: bias, rate, and regulation. Annals of the New York Academy of Sciences. 764: 158-69. PMID 7486516 DOI: 10.1111/J.1749-6632.1995.Tb55820.X |
0.183 |
|
2019 |
Alosaimi MF, Shendi H, Beano A, Stafstrom K, El Hawary R, Meshaal S, Galal N, Pai SY, El-Marsafy A, Geha RS, Chou J. T cell mitochondrial dysfunction and lymphopenia in DOCK2-deficient patients. The Journal of Allergy and Clinical Immunology. PMID 30826364 DOI: 10.1016/j.jaci.2019.02.020 |
0.183 |
|
1987 |
Leung DY, Schneeberger EE, Siraganian RP, Geha RS, Bhan AK. The presence of IgE on macrophages and dendritic cells infiltrating into the skin lesion of atopic dermatitis. Clinical Immunology and Immunopathology. 42: 328-37. PMID 3549069 DOI: 10.1016/0090-1229(87)90021-3 |
0.183 |
|
2020 |
Wildermann C, Alosaimi M, Liebenehm S, Jacobsen E, Barth TFE, Möller P, Debatin KM, Schulz A, Sirin M, Abosoudah IF, Alkuraya FS, Geha RS, Hönig M. Successful hematopoietic stem cell transplantation in a 4-1BB deficient patient with EBV-induced lymphoproliferation. Clinical Immunology (Orlando, Fla.). 108639. PMID 33259966 DOI: 10.1016/j.clim.2020.108639 |
0.183 |
|
1993 |
Castigli E, Geha RS, Chatila T. Severe Combined Immunodeficiency with Selective T-Cell Cytokine Genes Pediatric Research. 33: S20-S23. DOI: 10.1203/00006450-199333011-00005 |
0.183 |
|
1993 |
Castigli E, Geha RS, Chatila T. Severe Combined Immunodeficiency with Selective T-Cell Cytokine Genes Pediatric Research. 33: S20-S23. DOI: 10.1203/00006450-199304001-00005 |
0.183 |
|
1998 |
Jabara HH, Buckley RH, Roberts JL, Lefranc G, Loiselet J, Khalil G, Geha RS. Role of JAK3 in CD40-Mediated Signaling Blood. 92: 2435-2440. DOI: 10.1182/BLOOD.V92.7.2435.2435_2435_2440 |
0.182 |
|
2002 |
Dedeoglu F, Castigli E, Jabara H, Brodeour S, Geha RS. Regulation of AID gene in B cells Journal of Allergy and Clinical Immunology. 109: S277-S277. DOI: 10.1016/S0091-6749(02)81979-0 |
0.182 |
|
1987 |
Gould HJ, Helm BA, Marsh PJ, Geha RS. Recombinant human IgE. International Archives of Allergy and Applied Immunology. 82: 392-3. PMID 2952601 DOI: 10.1159/000234235 |
0.181 |
|
1982 |
Leung DY, Rhodes AR, Geha RS. Enumeration of T cell subsets in atopic dermatitis using monoclonal antibodies. The Journal of Allergy and Clinical Immunology. 67: 450-5. PMID 6980906 DOI: 10.1016/0091-6749(81)90098-1 |
0.181 |
|
2014 |
Wurbel MA, Le Bras S, Ibourk M, Pardo M, McIntire MG, Coco D, Geha RS, Fiebiger E, Snapper SB. CCL25/CCR9 interactions are not essential for colitis development but are required for innate immune cell protection from chronic experimental murine colitis. Inflammatory Bowel Diseases. 20: 1165-76. PMID 24874458 DOI: 10.1097/MIB.0000000000000059 |
0.18 |
|
1987 |
Leung DY, Geha RS, Newburger JW, Burns JC, Fiers W, Lapierre LA, Pober JS. Two monokines, interleukin 1 and tumor necrosis factor, render cultured vascular endothelial cells susceptible to lysis by antibodies circulating during Kawasaki syndrome. The Journal of Experimental Medicine. 164: 1958-72. PMID 3491174 DOI: 10.1084/Jem.164.6.1958 |
0.18 |
|
1991 |
Sekaly RP, Croteau G, Bowman M, Scholl P, Burakoff S, Geha RS. The CD4 molecule is not always required for the T cell response to bacterial enterotoxins Journal of Experimental Medicine. 173: 367-371. PMID 1988539 DOI: 10.1084/Jem.173.2.367 |
0.179 |
|
2009 |
Oyoshi M, ElKhal A, Scott J, He R, Jin H, Wurbel M, Campbell J, Geha R. Epicutaneous Antigen Challenge of Orally Sensitized Mice Elicits Allergic Dermatitis by Redirecting α4β7 Gut Homing T Cells to the Skin Journal of Allergy and Clinical Immunology. 123: S70-S70. DOI: 10.1016/J.Jaci.2008.12.240 |
0.179 |
|
2016 |
Badran YR, Massaad MJ, Bainter W, Cangemi B, Naseem SU, Javad H, Al-Tamemi S, Geha RS, Chou J. Combined immunodeficiency due to a homozygous mutation in ORAI1 that deletes the C-terminus that interacts with STIM 1. Clinical Immunology (Orlando, Fla.). PMID 27063589 DOI: 10.1016/J.Clim.2016.03.012 |
0.179 |
|
1973 |
Geha RS, Rosen FS, Merler E. Identification and characterization of subpopulations of lymphocytes in human peripheral blood after fractionation on discontinuous gradients of albumin. The cellular defect in X-linked agammaglobulinemia. The Journal of Clinical Investigation. 52: 1726-34. PMID 4578158 DOI: 10.1172/JCI107354 |
0.178 |
|
1982 |
Leung DY, Siegel RL, Grady S, Krensky A, Meade R, Reinherz EL, Geha RS. Immunoregulatory abnormalities in mucocutaneous lymph node syndrome. Clinical Immunology and Immunopathology. 23: 100-12. PMID 7047030 DOI: 10.1016/0090-1229(82)90075-7 |
0.178 |
|
1991 |
Geha RS, Castigli E, Chatila T. Novel immune deficiencies: defective transcription of lymphokine genes. Clinical Immunology and Immunopathology. 61: S16-20. PMID 1934609 DOI: 10.1016/S0090-1229(05)80033-9 |
0.178 |
|
2019 |
Beaussant-Cohen S, Jaber F, Massaad MJ, Weeks S, Jones J, Alosaimi MF, Wallace J, Al-Herz W, Geha RS, Chou J. Combined immunodeficiency in a patient with deficiency of c-Rel. The Journal of Allergy and Clinical Immunology. PMID 31103457 DOI: 10.1016/J.Jaci.2019.05.003 |
0.177 |
|
2019 |
Çakan M, Aktay-Ayaz N, Karadağ ŞG, Tahir-Turanlı E, Stafstrom K, Bainter W, Geha RS, Chou J. Atypical phenotype of an old disease or typical phenotype of a new disease: deficiency of adenosine deaminase 2. The Turkish Journal of Pediatrics. 61: 413-417. PMID 31916720 DOI: 10.24953/turkjped.2019.03.014 |
0.176 |
|
2002 |
Alenius H, Laouini D, Woodward A, Mizoguchi E, Bhan AK, Castigli E, Oettgen HC, Geha RS. Mast cells regulate IFN-gamma expression in the skin and circulating IgE levels in allergen-induced skin inflammation. The Journal of Allergy and Clinical Immunology. 109: 106-13. PMID 11799374 DOI: 10.1067/MAI.2002.120553 |
0.175 |
|
1987 |
Chatila TA, Schwartz DH, Miller R, Geha RS. Requirement for mitogen, T cell-accessory cell contact, and interleukin 1 in the induction of resting T-cell proliferation. Clinical Immunology and Immunopathology. 44: 235-47. PMID 3111768 DOI: 10.1016/0090-1229(87)90068-7 |
0.175 |
|
1981 |
Geha RS. Dynamics of human circulating antigen reactive cells following secondary immunization with tetanus toxoid. Clinical Immunology and Immunopathology. 19: 196-205. PMID 6971719 DOI: 10.1016/0090-1229(81)90063-5 |
0.175 |
|
1988 |
Helm B, Marsh P, Vercelli D, Padlan E, Gould H, Geha R. The mast cell binding site on human immunoglobulin E. Nature. 331: 180-3. PMID 3123993 DOI: 10.1038/331180a0 |
0.175 |
|
1993 |
Mourad W, Al-Daccak R, Chatila T, Geha RS. Staphylococcal superantigens as inducers of signal transduction in MHC class II-positive cells Seminars in Immunology. 5: 47-55. PMID 8467095 DOI: 10.1006/Smim.1993.1007 |
0.174 |
|
2010 |
Diamond B, Cunningham-Rundles C, Fischer A, Geha R, Notarangelo L, Ochs H, Rotrosen D, Terhorst C. Josiah F. Wedgwood (1950-2009). The Journal of Allergy and Clinical Immunology. 125: 506. PMID 20042229 DOI: 10.1016/J.Jaci.2009.12.932 |
0.174 |
|
1992 |
Shapira SK, Vercelli D, Jabara HH, Fu SM, Geha RS. Molecular analysis of the induction of immunoglobulin E synthesis in human B cells by interleukin 4 and engagement of CD40 antigen. The Journal of Experimental Medicine. 175: 289-92. PMID 1370532 DOI: 10.1084/Jem.175.1.289 |
0.174 |
|
2021 |
Leyva-Castillo JM, Geha RS. Cutaneous Type 2 Innate Lymphoid Cells Come in Distinct Flavors. Jid Innovations : Skin Science From Molecules to Population Health. 1: 100059. PMID 34909740 DOI: 10.1016/j.xjidi.2021.100059 |
0.174 |
|
1985 |
Umetsu DT, Yunis EJ, Matsui Y, Jabara HH, Geha RS. HLA-DR-4-associated alloreactivity of an HLA-DR-3-restricted human tetanus toxoid-specific T cell clone: inhibition of both reactivities by an alloantiserum. European Journal of Immunology. 15: 356-61. PMID 3157581 DOI: 10.1002/eji.1830150410 |
0.173 |
|
2016 |
Sobh A, Chou J, Schneider L, Geha RS, Massaad MJ. Chronic mucocutaneous candidiasis associated with an SH2 domain gain-of-function mutation that enhances STAT1 phosphorylation. The Journal of Allergy and Clinical Immunology. PMID 26948078 DOI: 10.1016/J.Jaci.2015.12.1320 |
0.172 |
|
1996 |
Matsumoto M, Lo SF, Carruthers CJL, Min J, Mariathasan S, Huang G, Plas DR, Martin SM, Geha RS, Nahm MH, Chaplin DD. Affinity maturation without germinal centres in lymphotoxin-α- deficient mice Nature. 382: 462-466. PMID 8684487 DOI: 10.1038/382462A0 |
0.172 |
|
1999 |
Vaduva G, Martinez-Quiles N, Anton IM, Martin NC, Geha RS, Hopper AK, Ramesh N. The human WASP-interacting protein, WIP, activates the cell polarity pathway in yeast. The Journal of Biological Chemistry. 274: 17103-8. PMID 10358064 DOI: 10.1074/Jbc.274.24.17103 |
0.172 |
|
1995 |
Jabara HH, Vercelli D, Schneider LC, Williams DP, Genbauffe FS, Poisson LR, Waters CA, Geha RS. Interleukin-4 receptor expression by human B cells: functional analysis with a human interleukin-4 toxin, DAB389IL-4. The Journal of Allergy and Clinical Immunology. 95: 893-900. PMID 7722171 DOI: 10.1016/S0091-6749(95)70134-6 |
0.171 |
|
2016 |
Badran YR, Rajab M, Hanna-Wakim R, Bainter W, Cangemi B, Massaad MJ, Dbaibo G, Geha RS, Chou J. Mutations in pyrin masquerading as a primary immunodeficiency. Clinical Immunology (Orlando, Fla.). PMID 27538774 DOI: 10.1016/J.Clim.2016.08.016 |
0.171 |
|
2014 |
Janssen E, Tsitsikov E, Al-Herz W, Lefranc G, Megarbane A, Dasouki M, Bonilla FA, Chatila T, Schneider L, Geha RS. Flow cytometry biomarkers distinguish DOCK8 deficiency from severe atopic dermatitis. Clinical Immunology (Orlando, Fla.). 150: 220-4. PMID 24440647 DOI: 10.1016/J.Clim.2013.12.006 |
0.171 |
|
1991 |
GEHA R, IABARA H, SHAPIRA S, SCHNEIDER L, ALFIERI C, MOODY C, KIEFF E, VERCELLI D. 418 rIL-4 and EBV induce germ-line and mature Cε transcripts in human B cells Journal of Allergy and Clinical Immunology. 87: 244. DOI: 10.1016/0091-6749(91)91701-T |
0.17 |
|
1995 |
Loh RK, Jabara HH, Ren CL, Fu SM, Vercelli D, Geha RS. Role of protein tyrosine kinases and phosphatases in isotype switching: crosslinking CD45 to CD40 inhibits IgE isotype switching in human B cells. Immunology Letters. 45: 99-106. PMID 7542629 DOI: 10.1016/0165-2478(94)00233-H |
0.17 |
|
1997 |
Wright DA, Futcher B, Ghosh P, Geha RS. Association of human fas (CD95) with a ubiquitin-conjugating enzyme (UBC-FAP). The Journal of Biological Chemistry. 271: 31037-43. PMID 8940097 DOI: 10.1074/jbc.271.49.31037 |
0.17 |
|
1978 |
Geha RS. Circulating immune complexes and activation of the complement sequence in acute allergic bronchopulmonary aspergillosis. The Journal of Allergy and Clinical Immunology. 60: 357-9. PMID 144747 DOI: 10.1016/0091-6749(77)90066-5 |
0.17 |
|
2014 |
Keles S, Jabara HH, Reisli I, McDonald DR, Barlan I, Hanna-Wakim R, Dbaibo G, Lefranc G, Al-Herz W, Geha RS, Chatila TA. Plasmacytoid dendritic cell depletion in DOCK8 deficiency: rescue of severe herpetic infections with IFN-α 2b therapy. The Journal of Allergy and Clinical Immunology. 133: 1753-5.e3. PMID 24767873 DOI: 10.1016/j.jaci.2014.03.032 |
0.17 |
|
2021 |
Das M, Leyva-Castillo JM, Geha RS. Basophils: the cell that itches. The Journal of Allergy and Clinical Immunology. PMID 34147536 DOI: 10.1016/j.jaci.2021.06.010 |
0.169 |
|
1991 |
LUE K, LAUENER R, GEHA R, VERCELLI D. 106 Engagement of CD14 on monocytes inhibits the proliferation of human T cells Journal of Allergy and Clinical Immunology. 87: 165. DOI: 10.1016/0091-6749(91)91389-B |
0.169 |
|
2002 |
Yalcindag A, Laouini D, Lu B, Bryce PJ, Humbles A, Oettgen HC, Gerard C, Geha RS. The complement receptor C3aR is an important regulator of Th cell polarization following epicutaneous sensitization with antigen Journal of Allergy and Clinical Immunology. 109: S279-S279. DOI: 10.1016/S0091-6749(02)81988-1 |
0.168 |
|
1981 |
Geha RS, Siegel L, Krensky A, Grady S, Meade R, Rosen FS, Leung D. 916 IMMUNOREGULATORY ABNORMALITIES IN KAWASAKI DISEASE Pediatric Research. 15: 595-595. DOI: 10.1203/00006450-198104001-00941 |
0.168 |
|
2018 |
Cohen SB, Bainter W, Johnson JL, Lin TY, Wong JCY, Wallace J, Jones J, Mir F, Qamar F, Cantley LC, Geha RS, Chou J. Human primary immunodeficiency caused by expression of a kinase-dead p110δ mutant. The Journal of Allergy and Clinical Immunology. PMID 30336224 DOI: 10.1016/J.Jaci.2018.10.005 |
0.168 |
|
2020 |
Leyva-Castillo JM, Das M, Artru E, Yoon Y, Galand C, Geha R. Mast cell-derived IL-13 downregulates IL-12 production by skin dendritic cells to inhibit the Th1 response to cutaneous antigen exposure. The Journal of Allergy and Clinical Immunology. PMID 33316284 DOI: 10.1016/j.jaci.2020.11.036 |
0.168 |
|
2004 |
Kawamoto S, Yalcindag A, Laouini D, Brodeur S, Bryce P, Lu B, Humbles AA, Oettgen H, Gerard C, Geha RS. The anaphylatoxin C3a downregulates the Th2 response to epicutaneously introduced antigen. The Journal of Clinical Investigation. 114: 399-407. PMID 15286806 DOI: 10.1172/Jci19082 |
0.167 |
|
1999 |
Dunn IF, Geha RS, Tsitsikov EN. Structure of the murine TRAF1 gene. Molecular Immunology. 36: 611-7. PMID 10499814 DOI: 10.1016/S0161-5890(99)00075-9 |
0.167 |
|
1980 |
Geha RS. Suppressor T cells in man Allergy and Asthma Proceedings. 1: 102-105. DOI: 10.2500/108854180779109453 |
0.166 |
|
2020 |
Rigoni R, Fontana E, Dobbs K, Marrella V, Taverniti V, Maina V, Facoetti A, D'Amico G, Al-Herz W, Cruz-Munoz ME, Schuetz C, Gennery AR, Garabedian EK, Giliani S, Draper D, ... ... Geha RS, et al. Cutaneous barrier leakage and gut inflammation drive skin disease in Omenn Syndrome. The Journal of Allergy and Clinical Immunology. PMID 32311393 DOI: 10.1016/j.jaci.2020.04.005 |
0.166 |
|
1994 |
Fuleihan R, Ramesh N, Geha RS. Role of CD40-CD40-ligand interaction in Ig-isotype switching. Current Opinion in Immunology. 5: 963-7. PMID 7507684 DOI: 10.1016/0952-7915(93)90113-7 |
0.166 |
|
1991 |
Lauener RP, Lue KH, Geha RS, Vercelli D. 2 Engagement of the monocyte antigen CD14 induces a state of IL-2 unresponsiveness in T cells Pediatric Research. 30: 628-628. DOI: 10.1203/00006450-199112000-00032 |
0.166 |
|
2024 |
Wilkie H, Das M, Pelovitz T, Bainter W, Woods B, Alasharee M, Sobh A, Baris S, Eltan SB, Al-Herz W, Barbouche MR, Ben-Mustapha I, Ben-Ali M, Sallam MTH, Awad A, ... ... Geha RS, et al. Treg cell dysfunction and cutaneous exposure to S. aureus underlie eczema in DOCK8 deficiency. The Journal of Allergy and Clinical Immunology. PMID 38185418 DOI: 10.1016/j.jaci.2023.12.020 |
0.166 |
|
1993 |
Trede NS, Chatila T, Geha RS. Activator protein-1 (AP-1) is stimulated by microbial superantigens in human monocytic cells. European Journal of Immunology. 23: 2129-35. PMID 8370396 DOI: 10.1002/Eji.1830230913 |
0.164 |
|
2013 |
Watanabe Y, Sasahara Y, Ramesh N, Massaad MJ, Yeng Looi C, Kumaki S, Kure S, Geha RS, Tsuchiya S. T-cell receptor ligation causes Wiskott-Aldrich syndrome protein degradation and F-actin assembly downregulation. The Journal of Allergy and Clinical Immunology. 132: 648-655.e1. PMID 23684068 DOI: 10.1016/J.Jaci.2013.03.046 |
0.164 |
|
2022 |
Nelson RW, Geha RS, McDonald DR. Inborn Errors of the Immune System Associated With Atopy. Frontiers in Immunology. 13: 860821. PMID 35572516 DOI: 10.3389/fimmu.2022.860821 |
0.162 |
|
2022 |
Jamee M, Azizi G, Baris S, Karakoc-Aydiner E, Ozen A, Kiliç SŞ, Kose H, Chavoshzadeh Z, Mahdaviani SA, Momen T, Shamsian BS, Fallahi M, Sharafian S, Gülez N, Aygun A, ... ... Geha RS, et al. Clinical, immunological, molecular and therapeutic findings in monogenic immune dysregulation diseases: Middle East and North Africa registry. Clinical Immunology (Orlando, Fla.). 244: 109131. PMID 36179983 DOI: 10.1016/j.clim.2022.109131 |
0.162 |
|
1985 |
Geha RS. Idiotypic-antiidiotypic interactions in man. La Ricerca in Clinica E in Laboratorio. 15: 1-8. PMID 3158061 DOI: 10.1007/BF03029155 |
0.162 |
|
1974 |
Geha RS, Merler E. Response of human thymus-derived (T) and non-thymus-derived (B) lymphocytes to mitogenic stimulation in vitro. European Journal of Immunology. 4: 193-9. PMID 4605055 DOI: 10.1002/eji.1830040308 |
0.161 |
|
1996 |
Morio T, Hanissian S, Geha RS. Characterization of a 23-kDa protein associated with CD40. Proceedings of the National Academy of Sciences of the United States of America. 92: 11633-6. PMID 8524818 DOI: 10.1073/pnas.92.25.11633 |
0.161 |
|
2000 |
Pivniouk VI, Geha RS. The role of SLP-76 and LAT in lymphocyte development. Current Opinion in Immunology. 12: 173-8. PMID 10712938 DOI: 10.1016/S0952-7915(99)00068-0 |
0.16 |
|
2007 |
He R, Oyoshi MK, Jin H, Geha RS. Epicutaneous antigen exposure induces a Th17 response that drives airway inflammation after inhalation challenge. Proceedings of the National Academy of Sciences of the United States of America. 104: 15817-22. PMID 17893340 DOI: 10.1073/pnas.0706942104 |
0.16 |
|
1980 |
Geha RS. Suppressor T cells in human allergic disease. The Journal of Allergy and Clinical Immunology. 64: 477-8. PMID 159919 DOI: 10.1016/0091-6749(79)90055-1 |
0.16 |
|
2012 |
Al-Herz W, Ragupathy R, Massaad MJ, Al-Attiyah R, Nanda A, Engelhardt KR, Grimbacher B, Notarangelo L, Chatila T, Geha RS. Clinical, immunologic and genetic profiles of DOCK8-deficient patients in Kuwait. Clinical Immunology (Orlando, Fla.). 143: 266-72. PMID 22534316 DOI: 10.1016/J.Clim.2012.03.002 |
0.16 |
|
2011 |
Oyoshi M, Larson R, Ziegler S, Geha R. Mechanical Injury Polarizes Skin Dendritic Cells to Elicit a Th2 Response by Inducing Cutaneous TSLP Expression Journal of Allergy and Clinical Immunology. 127: AB259-AB259. DOI: 10.1016/J.Jaci.2010.12.1031 |
0.16 |
|
2020 |
Li P, Hu M, Wang C, Feng X, Zhao Z, Yang Y, Sahoo N, Gu M, Yang Y, Xiao S, Sah R, Cover TL, Chou J, Geha R, Benavides F, et al. LRRC8 family proteins within lysosomes regulate cellular osmoregulation and enhance cell survival to multiple physiological stresses. Proceedings of the National Academy of Sciences of the United States of America. PMID 33139539 DOI: 10.1073/pnas.2016539117 |
0.16 |
|
1982 |
Siegel RL, Yunis EJ, Geha RS. Nature of the immunogenic moiety recognized by the human T cell proliferating in response to trinitrophenyl-modified self-antigens. Human Immunology. 4: 287-99. PMID 6811516 DOI: 10.1016/0198-8859(82)90002-7 |
0.159 |
|
2003 |
Orange JS, Harris KE, Andzelm MM, Valter MM, Geha RS, Strominger JL. The mature activating natural killer cell immunologic synapse is formed in distinct stages. Proceedings of the National Academy of Sciences of the United States of America. 100: 14151-6. PMID 14612578 DOI: 10.1073/Pnas.1835830100 |
0.159 |
|
1982 |
Geha R, Yunis E, Siegel R. Nature of the immunogeneic moeity recognized by the human T cell proliferating in response to trinitrophenyl modified self antigens Journal of Allergy and Clinical Immunology. 69: 129. DOI: 10.1016/S0091-6749(62)80430-8 |
0.158 |
|
1998 |
Spergel JM, Mizoguchi E, Brewer JP, Martin TR, Bhan AK, Geha RS. Epicutaneous sensitization with protein antigen induces localized allergic dermatitis and hyperresponsiveness to methacholine after single exposure to aerosolized antigen in mice Journal of Clinical Investigation. 101: 1614-1622. PMID 9541491 DOI: 10.1172/JCI1647 |
0.158 |
|
2010 |
Wang J, Geha R, Oyoshi M. The TLR9 Ligand CpG Promotes Cutaneous Expression of IFN-γ the Skin in a Mouse Model of Atopic Dermatitis (AD) Journal of Allergy and Clinical Immunology. 125: AB106. DOI: 10.1016/j.jaci.2009.12.419 |
0.158 |
|
1995 |
Worm M, Geha RS. CD40-mediated lymphotoxin alpha expression in human B cells is tyrosine kinase dependent. European Journal of Immunology. 25: 2438-44. PMID 7589108 DOI: 10.1002/eji.1830250905 |
0.158 |
|
2010 |
Oyoshi MK, Larson RP, Ziegler SF, Geha RS. Mechanical injury polarizes skin dendritic cells to elicit a T(H)2 response by inducing cutaneous thymic stromal lymphopoietin expression. The Journal of Allergy and Clinical Immunology. 126: 976-84, 984.e1-5. PMID 21050944 DOI: 10.1016/J.Jaci.2010.08.041 |
0.157 |
|
2013 |
Saadoun D, Romberg N, Chamberlain N, Geha R, Grimbacher B, Cunningham Rundles C, Meffre E. Les mutations de TACI associées aux DICV affectent la sélection et l’activation des lymphocytes B autoréactifs La Revue De MéDecine Interne. 34: A35. DOI: 10.1016/j.revmed.2013.03.231 |
0.157 |
|
1994 |
Wang AV, Scholl PR, Geha RS. Physical and functional association of the high affinity immunoglobulin G receptor (Fc gamma RI) with the kinases Hck and Lyn. The Journal of Experimental Medicine. 180: 1165-70. PMID 8064233 DOI: 10.1084/jem.180.3.1165 |
0.157 |
|
1975 |
Geha RS, Merler E. Human lymphocyte mitogenic factor: synthesis by sensitized thymus-derived lymphocytes, dependence of expression on the presence of antigen. Cellular Immunology. 10: 86-104. PMID 4549021 DOI: 10.1016/0008-8749(74)90154-3 |
0.157 |
|
2011 |
Jabara HH, Angelini F, Brodeur SR, Geha RS. Ligation of CD46 to CD40 inhibits CD40 signaling in B cells. International Immunology. 23: 215-21. PMID 21393637 DOI: 10.1093/intimm/dxq474 |
0.157 |
|
1999 |
Spergel JM, Mizoguchi E, Oettgen H, Bhan AK, Geha RS. Roles of TH1 and TH2 cytokines in a murine model of allergic dermatitis. The Journal of Clinical Investigation. 103: 1103-11. PMID 10207161 DOI: 10.1172/JCI5669 |
0.157 |
|
2003 |
Antón IM, Saville SP, Byrne MJ, Curcio C, Ramesh N, Hartwig JH, Geha RS. WIP participates in actin reorganization and ruffle formation induced by PDGF. Journal of Cell Science. 116: 2443-51. PMID 12724353 DOI: 10.1242/jcs.00433 |
0.157 |
|
2023 |
Wilkie H, Timilshina M, Das M, Pelovitz T, Geha RS. DOCK8 is essential for neutrophil mediated clearance of cutaneous S. aureus infection. Clinical Immunology (Orlando, Fla.). 109681. PMID 37385324 DOI: 10.1016/j.clim.2023.109681 |
0.156 |
|
1990 |
Scholl PR, Sekaly RP, Diez A, Glimcher LH, Geha RS. Binding of toxic shock syndrome toxin-1 to murine major histocompatibility complex class II molecules European Journal of Immunology. 20: 1911-1916. PMID 2209697 DOI: 10.1002/Eji.1830200907 |
0.155 |
|
2009 |
Jin H, Oyoshi MK, Le Y, Bianchi T, Koduru S, Mathias CB, Kumar L, Le Bras S, Young D, Collins M, Grusby MJ, Wenzel J, Bieber T, Boes M, Silberstein LE, ... ... Geha RS, et al. IL-21R is essential for epicutaneous sensitization and allergic skin inflammation in humans and mice. The Journal of Clinical Investigation. 119: 47-60. PMID 19075398 DOI: 10.1172/Jci32310 |
0.154 |
|
1995 |
Worm M, Geha RS. CD40 ligation induces lymphotoxin alpha gene expression in human B cells. International Immunology. 6: 1883-90. PMID 7535097 DOI: 10.1093/intimm/6.12.1883 |
0.153 |
|
1999 |
Morio T, Hanissian SH, Bacharier LB, Teraoka H, Nonoyama S, Seki M, Kondo J, Nakano H, Lee SK, Geha RS, Yata J. Ku in the cytoplasm associates with CD40 in human B cells and translocates into the nucleus following incubation with IL-4 and anti-CD40 mAb. Immunity. 11: 339-48. PMID 10514012 DOI: 10.1016/S1074-7613(00)80109-0 |
0.153 |
|
2006 |
Notarangelo L, Casanova JL, Conley ME, Chapel H, Fischer A, Puck J, Roifman C, Seger R, Geha RS. Primary immunodeficiency diseases: an update from the International Union of Immunological Societies Primary Immunodeficiency Diseases Classification Committee Meeting in Budapest, 2005. The Journal of Allergy and Clinical Immunology. 117: 883-96. PMID 16680902 DOI: 10.1016/j.jaci.2005.12.1347 |
0.153 |
|
2015 |
Chou J, Hsu JT, Bainter W, Al-Attiyah R, Al-Herz W, Geha RS. A novel mutation in NCF2 associated with autoimmune disease and a solitary late-onset infection. Clinical Immunology (Orlando, Fla.). 161: 128-130. PMID 26272171 DOI: 10.1016/j.clim.2015.08.003 |
0.153 |
|
1992 |
al-Rayes H, Pachas W, Mirza N, Ahern DJ, Geha RS, Vercelli D. IgE regulation and lymphokine patterns in aging humans. The Journal of Allergy and Clinical Immunology. 90: 630-6. PMID 1328343 DOI: 10.1016/0091-6749(92)90136-P |
0.152 |
|
2013 |
Leisten S, Oyoshi MK, Galand C, Hornick JL, Gurish MF, Geha RS. Development of skin lesions in filaggrin-deficient mice is dependent on adaptive immunity. The Journal of Allergy and Clinical Immunology. 131: 1247-50, 1250.e1. PMID 23540619 DOI: 10.1016/j.jaci.2012.12.1576 |
0.152 |
|
1994 |
Morio T, Geha RS, Chatila TA. Engagement of MHC class II molecules by staphylococcal superantigens activates src-type protein tyrosine kinases. European Journal of Immunology. 24: 651-8. PMID 7510238 DOI: 10.1002/eji.1830240325 |
0.152 |
|
2022 |
Leyva-Castillo JM, Sun L, Wu SY, Rockowitz S, Sliz P, Geha R. Single cell transcriptome profile of mouse skin undergoing antigen driven allergic inflammation recapitulates findings in atopic dermatitis skin lesions. The Journal of Allergy and Clinical Immunology. PMID 35300986 DOI: 10.1016/j.jaci.2022.03.002 |
0.15 |
|
2010 |
McDonald DR, Massaad MJ, Johnston A, Keles S, Chatila T, Geha RS, Pai SY. Successful engraftment of donor marrow after allogeneic hematopoietic cell transplantation in autosomal-recessive hyper-IgE syndrome caused by dedicator of cytokinesis 8 deficiency. The Journal of Allergy and Clinical Immunology. 126: 1304-5.e3. PMID 20810158 DOI: 10.1016/J.Jaci.2010.07.034 |
0.15 |
|
2021 |
Vavassori S, Chou J, Faletti LE, Haunerdinger V, Opitz L, Joset P, Fraser CJ, Prader S, Gao X, Schuch LA, Wagner M, Hoefele J, Maccari ME, Zhu Y, Elakis G, ... ... Geha R, et al. Multisystem Inflammation and Susceptibility to Viral infections in Human ZNFX1 Deficiency. The Journal of Allergy and Clinical Immunology. PMID 33872655 DOI: 10.1016/j.jaci.2021.03.045 |
0.149 |
|
1994 |
Trede NS, Morio T, Scholl PR, Geha RS, Chatila T. Early activation events induced by the staphylococcal superantigen toxic shock syndrome toxin-1 in human peripheral blood monocytes. Clinical Immunology and Immunopathology. 70: 137-44. PMID 8299229 DOI: 10.1006/Clin.1994.1021 |
0.148 |
|
1997 |
Hanissian SH, Geha RS. Jak3 is associated with CD40 and is critical for CD40 induction of gene expression in B cells. Immunity. 6: 379-87. PMID 9133417 DOI: 10.1016/S1074-7613(00)80281-2 |
0.147 |
|
2003 |
Geha RS, Jabara HH, Brodeur SR. The regulation of immunoglobulin E class-switch recombination. Nature Reviews. Immunology. 3: 721-32. PMID 12949496 DOI: 10.1038/nri1181 |
0.146 |
|
1979 |
Fineman SM, Mudawwar FB, Geha RS. Characteristics and mechanisms of action of the concanavalin A-activated suppressor cell in man. Cellular Immunology. 45: 120-32. PMID 313272 DOI: 10.1016/0008-8749(79)90367-8 |
0.146 |
|
1989 |
Scholl P, Diez A, Mourad W, Parsonnet J, Geha RS, Chatila T. Toxic shock syndrome toxin 1 binds to major histocompatibility complex class II molecules Proceedings of the National Academy of Sciences of the United States of America. 86: 4210-4214. PMID 2542966 DOI: 10.1073/Pnas.86.11.4210 |
0.145 |
|
2012 |
Oyoshi MK, He R, Kanaoka Y, ElKhal A, Kawamoto S, Lewis CN, Austen KF, Geha RS. Eosinophil-derived leukotriene C4 signals via type 2 cysteinyl leukotriene receptor to promote skin fibrosis in a mouse model of atopic dermatitis. Proceedings of the National Academy of Sciences of the United States of America. 109: 4992-7. PMID 22416124 DOI: 10.1073/pnas.1203127109 |
0.145 |
|
2008 |
Shinohara M, Koga T, Okamoto K, Sakaguchi S, Arai K, Yasuda H, Takai T, Kodama T, Morio T, Geha RS, Kitamura D, Kurosaki T, Ellmeier W, Takayanagi H. Tyrosine kinases Btk and Tec regulate osteoclast differentiation by linking RANK and ITAM signals. Cell. 132: 794-806. PMID 18329366 DOI: 10.1016/j.cell.2007.12.037 |
0.145 |
|
1983 |
Geha RS, Comunale M. Regulation of immunoglobulin E antibody synthesis in man by antiidiotypic antibodies. The Journal of Clinical Investigation. 71: 46-54. PMID 6600236 DOI: 10.1172/JCI110750 |
0.144 |
|
1989 |
Chatila T, Wood N, Parsonnet J, Rosen F, Geha RS. Toxic Shock Syndrome Toxin 1 Induces Inositol Phospholipid Turnover, Protein Kinase C Translocation, And Calcium Mobilization In Human T Cells Reviews of Infectious Diseases. 11: S330-S330. DOI: 10.1093/clinids/11.Supplement_1.S330-a |
0.143 |
|
1986 |
Quinti I, Brozek C, Wood N, Geha RS, Leung DY. Circulating IgG autoantibodies to IgE in atopic syndromes. The Journal of Allergy and Clinical Immunology. 77: 586-94. PMID 3958387 DOI: 10.1016/0091-6749(86)90350-7 |
0.143 |
|
1991 |
Shapira SK, Jabara HH, Thienes CP, Ahern DJ, Vercelli D, Gould HJ, Geha RS. Deletional switch recombination occurs in interleukin-4-induced isotype switching to IgE expression by human B cells Proceedings of the National Academy of Sciences of the United States of America. 88: 7528-7532. PMID 1881893 DOI: 10.1073/Pnas.88.17.7528 |
0.143 |
|
1997 |
Fujiwara H, Hanissian SH, Tsytsykova A, Geha RS. Homodimerization of the human interleukin 4 receptor alpha chain induces Cepsilon germline transcripts in B cells in the absence of the interleukin 2 receptor gamma chain. Proceedings of the National Academy of Sciences of the United States of America. 94: 5866-71. PMID 9159166 DOI: 10.1073/pnas.94.11.5866 |
0.142 |
|
2020 |
Jennifer B, Berg V, Modak M, Puck A, Seyerl-Jiresch M, Künig S, Zlabinger GJ, Steinberger P, Chou J, Geha RS, Öhler L, Yachie A, Choe H, Kraller M, Stockinger H, et al. Transferrin receptor 1 is a cellular receptor for human heme-albumin. Communications Biology. 3: 621. PMID 33110194 DOI: 10.1038/s42003-020-01294-5 |
0.142 |
|
1988 |
Leung D, Jabara H, Ackerman S, Vercelli D, Geha R. 542 Induction of IgE synthesis and eosinophil (EOS) differentiation by supernatants (SUPS) of a human type 2 (Th2) helper t cell clone Journal of Allergy and Clinical Immunology. 81: 303. DOI: 10.1016/0091-6749(88)90776-2 |
0.142 |
|
2015 |
Oyoshi MK, Beaupré J, Venturelli N, Lewis CN, Iwakura Y, Geha RS. Filaggrin deficiency promotes the dissemination of cutaneously inoculated vaccinia virus. The Journal of Allergy and Clinical Immunology. 135: 1511-1518.e6. PMID 25649082 DOI: 10.1016/j.jaci.2014.12.1923 |
0.142 |
|
1996 |
Tsitsikov EN, Fuleihan R, McIntosh K, Scholl PR, Geha RS. Cross-linking of Fc gamma receptors activates HIV-1 long terminal repeat-driven transcription in human monocytes. International Immunology. 7: 1665-70. PMID 8562512 DOI: 10.1093/intimm/7.10.1665 |
0.141 |
|
1985 |
YOUNG M, LEUNG D, GEHA R. 17 Production of IgE potentiating factor by FCR+ human T cell lines Journal of Allergy and Clinical Immunology. 75: 109. DOI: 10.1016/0091-6749(85)90152-6 |
0.141 |
|
2002 |
Ma W, Bryce PJ, Humbles A, Laouini D, Yalcindag A, Alenius HT, Friend D, Oettgen HC, Gerard C, Geha RS. The CC chemokine receptor 3 is essential for skin eosinophilia and for airway hyper-responsiveness to inhaled antigen in a murine model of allergic skin inflammation Journal of Allergy and Clinical Immunology. 109: S256-S256. DOI: 10.1016/S0091-6749(02)81915-7 |
0.141 |
|
1995 |
Fuleihan R, Ahern D, Geha RS. CD40 ligand expression is developmentally regulated in human thymocytes. Clinical Immunology and Immunopathology. 76: 52-8. PMID 7606868 DOI: 10.1006/clin.1995.1087 |
0.14 |
|
1980 |
Mudawwar F, Awdeh Z, Ault K, Geha RS. Regulation of monoclonal immunoglobulin G synthesis by antiidiotypic antibody in a patient with hypogammaglobulinemia. The Journal of Clinical Investigation. 65: 1202-9. PMID 6767740 DOI: 10.1172/JCI109775 |
0.139 |
|
2016 |
Yoon J, Leyva-Castillo JM, Wang G, Galand C, Oyoshi MK, Kumar L, Hoff S, He R, Chervonsky A, Oppenheim JJ, Kuchroo VK, van den Brink MR, Malefyt RW, Tessier PA, Fuhlbrigge R, ... ... Geha RS, et al. IL-23 induced in keratinocytes by endogenous TLR4 ligands polarizes dendritic cells to drive IL-22 responses to skin immunization. The Journal of Experimental Medicine. PMID 27551155 DOI: 10.1084/Jem.20150376 |
0.139 |
|
1999 |
Bacharier LB, Geha RS. Regulation of IgE synthesis: the molecular basis and implications for clinical modulation. Allergy and Asthma Proceedings. 20: 1-8. PMID 10076703 DOI: 10.2500/108854199778681558 |
0.138 |
|
2001 |
Geha RS, Meltzer EO. Desloratadine: A new, nonsedating, oral antihistamine Journal of Allergy and Clinical Immunology. 107: 751-762. PMID 11295678 DOI: 10.1067/MAI.2001.114239 |
0.138 |
|
1994 |
Ren CL, Morio T, Fu SM, Geha RS. Signal transduction via CD40 involves activation of lyn kinase and phosphatidylinositol-3-kinase, and phosphorylation of phospholipase C gamma 2. The Journal of Experimental Medicine. 179: 673-80. PMID 7507510 DOI: 10.1084/jem.179.2.673 |
0.138 |
|
2009 |
Oyoshi MK, He R, Kumar L, Yoon J, Geha RS. Cellular and molecular mechanisms in atopic dermatitis. Advances in Immunology. 102: 135-226. PMID 19477321 DOI: 10.1016/S0065-2776(09)01203-6 |
0.138 |
|
2012 |
Garber JJ, Takeshima F, Antón IM, Oyoshi MK, Lyubimova A, Kapoor A, Shibata T, Chen F, Alt FW, Geha RS, Leong JM, Snapper SB. Enteropathogenic Escherichia coli and vaccinia virus do not require the family of WASP-interacting proteins for pathogen-induced actin assembly. Infection and Immunity. 80: 4071-7. PMID 22966049 DOI: 10.1128/Iai.06148-11 |
0.138 |
|
2018 |
Leyva-Castillo J, Geha RS. Skin Innate Lymphoid Cells Type 2 Activated by Keratinocyte-derived IL-25 promote IL-13-mediated skin allergic inflammation Journal of Allergy and Clinical Immunology. 141: AB187. DOI: 10.1016/j.jaci.2017.12.595 |
0.137 |
|
2010 |
Picard C, von Bernuth H, Ghandil P, Chrabieh M, Levy O, Arkwright PD, McDonald D, Geha RS, Takada H, Krause JC, Creech CB, Ku CL, Ehl S, Maródi L, Al-Muhsen S, et al. Clinical features and outcome of patients with IRAK-4 and MyD88 deficiency. Medicine. 89: 403-25. PMID 21057262 DOI: 10.1097/Md.0B013E3181Fd8Ec3 |
0.137 |
|
2013 |
Brauweiler AM, Bin L, Kim BE, Oyoshi MK, Geha RS, Goleva E, Leung DY. Filaggrin-dependent secretion of sphingomyelinase protects against staphylococcal α-toxin-induced keratinocyte death. The Journal of Allergy and Clinical Immunology. 131: 421-7.e1-2. PMID 23246020 DOI: 10.1016/j.jaci.2012.10.030 |
0.137 |
|
2007 |
Carman CV, Sage PT, Sciuto TE, de la Fuente MA, Geha RS, Ochs HD, Dvorak HF, Dvorak AM, Springer TA. Transcellular diapedesis is initiated by invasive podosomes. Immunity. 26: 784-97. PMID 17570692 DOI: 10.1016/J.Immuni.2007.04.015 |
0.136 |
|
2018 |
Ben Farhat K, Alosaimi MF, Shendi H, Al-Hammadi S, Jones J, Schwarz K, Schulz A, Alawdah LS, Burchett S, Albuhairi S, Whangbo J, Kwatra N, Shamseldin HE, Alkuraya FS, Chou J, ... Geha RS, et al. Immunologic reconstitution following hematopoietic stem cell transplantation despite lymph node paucity in NIK deficiency. The Journal of Allergy and Clinical Immunology. PMID 30445060 DOI: 10.1016/j.jaci.2018.11.003 |
0.136 |
|
2016 |
Nakatsuji T, Chen TH, Two AM, Chun KA, Narala S, Geha RS, Hata TR, Gallo RL. Staphylococcus aureus exploits epidermal barrier defects in atopic dermatitis to trigger cytokine expression. The Journal of Investigative Dermatology. PMID 27381887 DOI: 10.1016/J.Jid.2016.05.127 |
0.135 |
|
2010 |
Oyoshi M, Geha R. Filaggrin Deficient Mice Exhibit Th17-dominated Skin Inflammation and Increased Susceptibility to Inoculation With Vaccinia Virus Journal of Allergy and Clinical Immunology. 125: AB123. DOI: 10.1016/J.JACI.2009.12.485 |
0.135 |
|
2003 |
Laouini D, Alenius H, Bryce P, Oettgen H, Tsitsikov E, Geha RS. IL-10 is critical for Th2 responses in a murine model of allergic dermatitis. The Journal of Clinical Investigation. 112: 1058-66. PMID 14523043 DOI: 10.1172/JCI18246 |
0.135 |
|
2024 |
Strakosha M, Vega-Mendoza D, Kane J, Jain A, Sun L, Rockowitz S, Elkins M, Miyake K, Chou J, Karasuyama H, Geha RS, Leyva-Castillo JM. Basophils play a protective role in the recovery of skin barrier function from mechanical injury in mice. The Journal of Investigative Dermatology. PMID 38286187 DOI: 10.1016/j.jid.2023.12.024 |
0.134 |
|
1978 |
Fineman SM, Mudaw-War FB, Geha RS. 696 IDENTIFICATION AND CHARACTERIZATION OF HUMAN SUPPRESSOR LYMPHOCYTES Pediatric Research. 12: 479-479. DOI: 10.1203/00006450-197804001-00701 |
0.133 |
|
1982 |
Leung DY, Geha RS. Immune mechanisms in atopic dermatitis. Springer Seminars in Immunopathology. 4: 275-91. PMID 7041302 DOI: 10.1007/BF01892182 |
0.133 |
|
1999 |
Tsytsykova AV, Tsitsikov EN, Wright DA, Futcher B, Geha RS. The mouse genome contains two expressed intronless retroposed pseudogenes for the sentrin/sumo-1/PIC1 conjugating enzyme Ubc9. Molecular Immunology. 35: 1057-67. PMID 10068040 DOI: 10.1016/S0161-5890(98)00094-7 |
0.132 |
|
1977 |
Geha RS. Origin of the antibody-dependent cytotoxic cell in man. Clinical Immunology and Immunopathology. 7: 253-61. PMID 324681 DOI: 10.1016/0090-1229(77)90052-6 |
0.132 |
|
2017 |
Liu H, Archer NK, Dillen CA, Wang Y, Ashbaugh AG, Ortines RV, Kao T, Lee SK, Cai SS, Miller RJ, Marchitto MC, Zhang E, Riggins DP, Plaut RD, Stibitz S, ... Geha RS, et al. Staphylococcus aureus Epicutaneous Exposure Drives Skin Inflammation via IL-36-Mediated T Cell Responses. Cell Host & Microbe. 22: 653-666.e5. PMID 29120743 DOI: 10.1016/j.chom.2017.10.006 |
0.132 |
|
2019 |
Farmer JR, Foldvari Z, Ujhazi B, De Ravin SS, Chen K, Bleesing JJH, Schuetz C, Al-Herz W, Abraham RS, Joshi AY, Costa-Carvalho BT, Buchbinder D, Booth C, Reiff A, Ferguson PJ, ... ... Geha RS, et al. Outcomes and treatment strategies for autoimmunity and hyperinflammation in patients with RAG deficiency. The Journal of Allergy and Clinical Immunology. in Practice. PMID 30877075 DOI: 10.1016/J.Jaip.2019.02.038 |
0.131 |
|
2012 |
Hidano S, Kitamura D, Kumar L, Geha RS, Goitsuka R. SLP-76 is required for high-affinity IgE receptor- and IL-3 receptor-mediated activation of basophils. International Immunology. 24: 719-27. PMID 22875843 DOI: 10.1093/intimm/dxs072 |
0.131 |
|
2003 |
Levy O, Orange JS, Hibberd P, Steinberg S, LaRussa P, Weinberg A, Wilson SB, Shaulov A, Fleisher G, Geha RS, Bonilla FA, Exley M. Disseminated varicella infection due to the vaccine strain of varicella-zoster virus, in a patient with a novel deficiency in natural killer T cells. The Journal of Infectious Diseases. 188: 948-53. PMID 14513412 DOI: 10.1086/378503 |
0.131 |
|
1990 |
Boguniewicz M, Jaffe HS, Izu A, Sullivan MJ, York D, Geha RS, Leung DY. Recombinant gamma interferon in treatment of patients with atopic dermatitis and elevated IgE levels. The American Journal of Medicine. 88: 365-70. PMID 2109531 DOI: 10.1016/0002-9343(90)90490-5 |
0.131 |
|
1993 |
Scholl PR, Geha RS. Physical association between the high-affinity IgG receptor (Fc gamma RI) and the gamma subunit of the high-affinity IgE receptor (Fc epsilon RI gamma). Proceedings of the National Academy of Sciences of the United States of America. 90: 8847-50. PMID 8415618 DOI: 10.1073/pnas.90.19.8847 |
0.131 |
|
1991 |
Schneider L, Antin J, Weinstein H, Abrams J, Pearce M, Geha R, Vercelli D. Lymphokine profile in bone marrow transplant recipients Blood. 78: 3076-3080. DOI: 10.1182/blood.v78.11.3076.3076 |
0.13 |
|
1988 |
Vercelli D, Jabara HH, Lee BW, Woodland N, Geha RS, Leung DY. Human recombinant interleukin 4 induces Fc epsilon R2/CD23 on normal human monocytes. The Journal of Experimental Medicine. 167: 1406-16. PMID 2965737 DOI: 10.1084/Jem.167.4.1406 |
0.13 |
|
1991 |
Schneider L, Antin J, Weinstein H, Abrams J, Pearce M, Geha R, Vercelli D. Lymphokine profile in bone marrow transplant recipients Blood. 78: 3076-3080. DOI: 10.1182/Blood.V78.11.3076.Bloodjournal78113076 |
0.13 |
|
2001 |
Oettgen HC, Geha RS. IgE regulation and roles in asthma pathogenesis. The Journal of Allergy and Clinical Immunology. 107: 429-40. PMID 11240941 DOI: 10.1067/MAI.2001.113759 |
0.129 |
|
1980 |
Geha RS, Rappaport JM, Twarog FJ, Parkman R, Rosen FS. Increased serum immunoglobulin E levels following allogeneic bone marrow transplantation. The Journal of Allergy and Clinical Immunology. 66: 78-81. PMID 6991585 DOI: 10.1016/0091-6749(80)90142-6 |
0.128 |
|
2018 |
Aydin SE, Freeman AF, Al-Herz W, Al-Mousa HA, Arnaout RK, Aydin RC, Barlogis V, Belohradsky BH, Bonfim C, Bredius RG, Chu JI, Ciocarlie OC, Doğu F, Gaspar HB, Geha RS, et al. Hematopoietic stem cell transplantation as treatment for patients with DOCK8 deficiency. The Journal of Allergy and Clinical Immunology. in Practice. PMID 30391550 DOI: 10.1016/j.jaip.2018.10.035 |
0.128 |
|
2019 |
Alosaimi MF, Maciag MC, Platt CD, Geha RS, Chou J, Bartnikas LM. A novel variant in STAT2 presenting with hemophagocytic lymphohistiocytosis. The Journal of Allergy and Clinical Immunology. PMID 31102697 DOI: 10.1016/J.Jaci.2019.05.008 |
0.128 |
|
1994 |
Tsitsikov EN, Ramesh N, Geha RS. Structure of the murine CD40 ligand gene. Molecular Immunology. 31: 895-900. PMID 7520529 DOI: 10.1016/0161-5890(94)90009-4 |
0.128 |
|
2001 |
Martinez-Quiles N, Rohatgi R, Antón IM, Medina M, Saville SP, Miki H, Yamaguchi H, Takenawa T, Hartwig JH, Geha RS, Ramesh N. WIP regulates N-WASP-mediated actin polymerization and filopodium formation. Nature Cell Biology. 3: 484-91. PMID 11331876 DOI: 10.1038/35074551 |
0.128 |
|
1981 |
Geha RS. Regulation of the immune response by idiotypic-antiidiotypic interactions. The New England Journal of Medicine. 305: 25-8. PMID 6164922 DOI: 10.1056/NEJM198107023050105 |
0.128 |
|
2020 |
Lee PY, Platt CD, Weeks S, Grace RF, Maher G, Gauthier K, Devana S, Vitali S, Randolph AG, McDonald DR, Geha RS, Chou J. Immune dysregulation and Multisystem Inflammatory Syndrome in Children (MIS-C) in individuals with haploinsufficiency of SOCS1. The Journal of Allergy and Clinical Immunology. PMID 32853638 DOI: 10.1016/J.Jaci.2020.07.033 |
0.127 |
|
1999 |
Förster E, Krenger W, Joergensen J, Hof R, Geha RS, Holländer GA. Contribution of CD40-CD154-mediated costimulation to an alloresponse in vivo. Transplantation. 67: 1284-7. PMID 10342324 DOI: 10.1097/00007890-199905150-00016 |
0.127 |
|
2003 |
Orange JS, Geha RS, Bonilla FA. Acute chylothorax in children: selective retention of memory T cells and natural killer cells. The Journal of Pediatrics. 143: 243-9. PMID 12970641 DOI: 10.1067/S0022-3476(03)00305-6 |
0.127 |
|
2011 |
Oyoshi MK, Wang JY, Geha RS. Immunization with modified vaccinia virus Ankara prevents eczema vaccinatum in a murine model of atopic dermatitis. The Journal of Allergy and Clinical Immunology. 128: 890-892.e3. PMID 21820712 DOI: 10.1016/j.jaci.2011.06.042 |
0.126 |
|
2021 |
Harb H, Stephen-Victor E, Crestani E, Benamar M, Massoud A, Cui Y, Charbonnier LM, Arbag S, Baris S, Cunnigham A, Leyva-Castillo JM, Geha RS, Mousavi AJ, Guennewig B, Schmitz-Abe K, et al. Author Correction: A regulatory T cell Notch4-GDF15 axis licenses tissue inflammation in asthma. Nature Immunology. PMID 33903767 DOI: 10.1038/s41590-021-00929-x |
0.126 |
|
2004 |
Martinez-Quiles N, Ho HY, Kirschner MW, Ramesh N, Geha RS. Erk/Src phosphorylation of cortactin acts as a switch on-switch off mechanism that controls its ability to activate N-WASP. Molecular and Cellular Biology. 24: 5269-80. PMID 15169891 DOI: 10.1128/Mcb.24.12.5269-5280.2004 |
0.125 |
|
1985 |
Umetsu DT, Hahn JS, Perez-Atayde AR, Geha RS. Serum sickness triggered by anaphylaxis: a complication of immunotherapy. The Journal of Allergy and Clinical Immunology. 76: 713-8. PMID 4056255 DOI: 10.1016/0091-6749(85)90676-1 |
0.125 |
|
1995 |
Worm M, Geha RS. Activation of tumor necrosis factor-alpha and lymphotoxin-alpha via anti-CD40 in human B cells. International Archives of Allergy and Immunology. 107: 368-9. PMID 7542089 DOI: 10.1159/000237037 |
0.125 |
|
2020 |
Harb H, Stephen-Victor E, Crestani E, Benamar M, Massoud A, Cui Y, Charbonnier LM, Arbag S, Baris S, Cunnigham A, Leyva-Castillo JM, Geha RS, Mousavi AJ, Guennewig B, Schmitz-Abe K, et al. Author Correction: A regulatory T cell Notch4-GDF15 axis licenses tissue inflammation in asthma. Nature Immunology. PMID 33214720 DOI: 10.1038/s41590-020-00841-w |
0.125 |
|
1997 |
Morio T, Chatila T, Geha RS. HIV glycoprotein gp120 inhibits TCR-CD3-mediated activation of fyn and lck. International Immunology. 9: 53-64. PMID 9043947 DOI: 10.1093/intimm/9.1.53 |
0.125 |
|
2021 |
Aghamohammadi A, Rezaei N, Yazdani R, Delavari S, Kutukculer N, Topyildiz E, Ozen A, Baris S, Karakoc-Aydiner E, Kilic SS, Kose H, Gulez N, Genel F, Reisli I, Djenouhat K, ... ... Geha RS, et al. Consensus Middle East and North Africa Registry on Inborn Errors of Immunity. Journal of Clinical Immunology. PMID 34052995 DOI: 10.1007/s10875-021-01053-z |
0.125 |
|
2003 |
Bryce P, Geha R, Oettgen H. Desloratadine inhibit T-cell responses, airway inflamation, and bronchial hyperresponsiveness (BHR) in murine models of asthma Journal of Allergy and Clinical Immunology. 111: S262. DOI: 10.1016/S0091-6749(03)80937-5 |
0.125 |
|
2006 |
Yalcindag A, He R, Laouini D, Alenius H, Carroll M, Oettgen HC, Geha RS. The complement component C3 plays a critical role in both Th1 and Th2 responses to antigen. The Journal of Allergy and Clinical Immunology. 117: 1455-61. PMID 16751013 DOI: 10.1016/J.JACI.2006.01.048 |
0.124 |
|
2005 |
Laouini D, Elkhal A, Yalcindag A, Kawamoto S, Oettgen H, Geha RS. COX-2 inhibition enhances the TH2 immune response to epicutaneous sensitization. The Journal of Allergy and Clinical Immunology. 116: 390-6. PMID 16083795 DOI: 10.1016/J.JACI.2005.03.042 |
0.123 |
|
2020 |
Wallace JG, Alosaimi M, Khayat CD, Jaber F, Almutairi A, Beaussant-Cohen S, Pinkus G, Fleming M, Mehawej C, Chou J, Geha RS. ITK deficiency presenting as Autoimmune Lymphoproliferative Syndrome. The Journal of Allergy and Clinical Immunology. PMID 32628964 DOI: 10.1016/j.jaci.2020.06.019 |
0.123 |
|
2015 |
Hoff S, Oyoshi MK, Macpherson A, Geha RS. The microbiota is important for IL-17A expression and neutrophil infiltration in lesional skin of Flg(ft/ft) mice. Clinical Immunology (Orlando, Fla.). 156: 128-30. PMID 25499749 DOI: 10.1016/j.clim.2014.12.001 |
0.123 |
|
2015 |
Gao L, Bin L, Rafaels NM, Huang L, Potee J, Ruczinski I, Beaty TH, Paller AS, Schneider LC, Gallo R, Hanifin JM, Beck LA, Geha RS, Mathias RA, Barnes KC, et al. Targeted deep sequencing identifies rare loss-of-function variants in IFNGR1 for risk of atopic dermatitis complicated by eczema herpeticum. The Journal of Allergy and Clinical Immunology. PMID 26343451 DOI: 10.1016/J.Jaci.2015.06.047 |
0.122 |
|
2014 |
Oyoshi MK, Beaupré J, Venturelli N, Geha RS. Thymic Stromal Lymphopoietin and Interleukin-33 Promote Skin Inflammation and Containment Of Vaccinia Virus In A Mouse Model Of Atopic Dermatitis Journal of Allergy and Clinical Immunology. 133: AB73. DOI: 10.1016/j.jaci.2013.12.282 |
0.122 |
|
1998 |
Dioun AF, Ewenstein BM, Geha RS, Schneider LC. IgE-mediated allergy and desensitization to factor IX in hemophilia B Journal of Allergy and Clinical Immunology. 102: 113-117. PMID 9679854 DOI: 10.1016/S0091-6749(98)70061-2 |
0.121 |
|
2017 |
Behe P, Foote JR, Levine AP, Platt CD, Chou J, Benavides F, Geha RS, Segal AW. The LRRC8A Mediated "Swell Activated" Chloride Conductance Is Dispensable for Vacuolar Homeostasis in Neutrophils. Frontiers in Pharmacology. 8: 262. PMID 28553230 DOI: 10.3389/Fphar.2017.00262 |
0.121 |
|
2018 |
Leyva-Castillo JM, Yoon J, Geha RS. IL-22 promotes allergic airway inflammation in epicutaneously sensitized mice. The Journal of Allergy and Clinical Immunology. PMID 29920352 DOI: 10.1016/j.jaci.2018.05.032 |
0.121 |
|
2019 |
Leyva-Castillo JM, Galand C, Kam C, Burton O, Gurish M, Musser MA, Goldsmith JD, Hait E, Nurko S, Brombacher F, Dong C, Finkelman FD, Lee RT, Ziegler S, Chiu I, ... ... Geha RS, et al. Mechanical Skin Injury Promotes Food Anaphylaxis by Driving Intestinal Mast Cell Expansion. Immunity. PMID 31027995 DOI: 10.1016/J.Immuni.2019.03.023 |
0.121 |
|
2009 |
Falet H, Marchetti MP, Hoffmeister KM, Massaad MJ, Geha RS, Hartwig JH. Platelet-associated IgAs and impaired GPVI responses in platelets lacking WIP Blood. 114: 4729-4737. PMID 19692704 DOI: 10.1182/Blood-2009-02-202721 |
0.121 |
|
2018 |
Geha RS, Leyva-Castillo J. Basophils and IL-4 Dampen the Protective Innate Immune Response Against Cutaneous Staphylococcus aureus Infection Journal of Allergy and Clinical Immunology. 141: AB18. DOI: 10.1016/J.JACI.2017.12.056 |
0.119 |
|
2018 |
Archer NK, Jo JH, Lee SK, Kim D, Smith B, Ortines RV, Wang Y, Marchitto MC, Ravipati A, Cai SS, Dillen CA, Liu H, Miller RJ, Ashbaugh AG, Uppal AS, ... ... Geha RS, et al. Injury, dysbiosis and filaggrin deficiency drive skin inflammation via keratinocyte IL-1α release. The Journal of Allergy and Clinical Immunology. PMID 30240702 DOI: 10.1016/j.jaci.2018.08.042 |
0.119 |
|
1991 |
Lauener RP, Goyert SM, Geha RS, Vercelli D. Interleukin 4 down-regulates the expression of CD14 in normal human monocytes. European Journal of Immunology. 20: 2375-81. PMID 1701391 DOI: 10.1002/Eji.1830201103 |
0.119 |
|
2005 |
Nishida K, Yamasaki S, Ito Y, Kabu K, Hattori K, Tezuka T, Nishizumi H, Kitamura D, Goitsuka R, Geha RS, Yamamoto T, Yagi T, Hirano T. Correction: FcεRI-mediated mast cell degranulation requires calcium-independent microtubule-dependent translocation of granules to the plasma membrane Journal of Cell Biology. 171: 177-177. DOI: 10.1083/jcb.200501111091905c |
0.119 |
|
1974 |
Geha RS, Schneeberger E, Gatien J, Rosen FS, Merler E. Synthesis of an M component by circulating B lymphocytes in severe combined immunodeficiency. The New England Journal of Medicine. 290: 726-8. PMID 4544349 DOI: 10.1056/NEJM197403282901308 |
0.118 |
|
2023 |
Leyva-Castillo JM, McGurk A, Strakosha M, Vega-Mendoza D, Smith S, Stafstrom K, Elkins M, Chou J, Wang YH, Geha RS. IL-4 Receptor alpha blockade dampens allergic inflammation and upregulates IL-17A expression to promote S. aureus clearance in antigen sensitized mouse skin. The Journal of Allergy and Clinical Immunology. PMID 37315811 DOI: 10.1016/j.jaci.2023.05.025 |
0.118 |
|
2021 |
Leyva-Castillo JM, Das M, Kane J, Strakosha M, Singh S, Wong DSH, Horswill AR, Karasuyama H, Brombacher F, Miller LS, Geha RS. Basophil-derived IL-4 promotes cutaneous Staphylococcus aureus infection. Jci Insight. 6. PMID 34747366 DOI: 10.1172/jci.insight.149953 |
0.118 |
|
2009 |
Notarangelo LD, Fischer A, Geha RS, Casanova JL, Chapel H, Conley ME, Cunningham-Rundles C, Etzioni A, Hammartröm L, Nonoyama S, Ochs HD, Puck J, Roifman C, Seger R, et al. Primary immunodeficiencies: 2009 update. The Journal of Allergy and Clinical Immunology. 124: 1161-78. PMID 20004777 DOI: 10.1016/j.jaci.2009.10.013 |
0.118 |
|
2017 |
Abolhassani H, Chou J, Bainter W, Platt C, Tavassoli M, Momen T, Tavakol M, Eslamian MH, Gharagozlou M, Movahedi M, Ghadami M, Hamidieh AA, Azizi G, Yazdani R, Afarideh M, ... ... Geha RS, et al. Clinical, Immunological and Genetic Spectrum of 696 Patients with Combined Immunodeficiency. The Journal of Allergy and Clinical Immunology. PMID 28916186 DOI: 10.1016/J.Jaci.2017.06.049 |
0.117 |
|
2021 |
Janssen E, Wilkie H, Geha RS. Macabre Th2 skewing in DOCK8 deficiency. The Journal of Allergy and Clinical Immunology. PMID 33667480 DOI: 10.1016/j.jaci.2021.02.025 |
0.117 |
|
Hide low-probability matches. |