Edel Hennessy - Publications

Affiliations: 
University of California, San Francisco, San Francisco, CA 
Area:
Neuroinflammation, Neurodegeneration

17 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Askew KE, Beverley J, Sigfridsson E, Szymkowiak S, Emelianova K, Dando O, Hardingham GE, Duncombe J, Hennessy E, Koudelka J, Samarasekera N, Salman RA, Smith C, Tavares AAS, Gomez-Nicola D, et al. Inhibiting CSF1R alleviates cerebrovascular white matter disease and cognitive impairment. Glia. PMID 37909242 DOI: 10.1002/glia.24481  0.31
2021 Lopez-Rodriguez AB, Hennessy E, Murray CL, Nazmi A, Delaney HJ, Healy D, Fagan SG, Rooney M, Stewart E, Lewis A, de Barra N, Scarry P, Riggs-Miller L, Boche D, Cunningham MO, et al. Acute systemic inflammation exacerbates neuroinflammation in Alzheimer's disease: IL-1β drives amplified responses in primed astrocytes and neuronal network dysfunction. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 34080771 DOI: 10.1002/alz.12341  0.437
2021 McGarry N, Murray CL, Garvey S, Wilkinson A, Tortorelli L, Ryan L, Hayden L, Healy D, Griffin EW, Hennessy E, Arumugam M, Skelly DT, Mitchell KJ, Cunningham C. Double stranded RNA drives anti-viral innate immune responses, sickness behavior and cognitive dysfunction dependent on dsRNA length, IFNAR1 expression and age. Brain, Behavior, and Immunity. PMID 33892139 DOI: 10.1016/j.bbi.2021.04.016  0.32
2021 McGarry N, Murray C, Garvey S, Wilkinson A, Tortorelli L, Ryan L, Hayden L, Healy D, Griffin EW, Hennessy E, Skelly DT, Arumugam M, Mitchell KJ, Cunningham C. Double stranded RNA drives innate immune responses, sickness behavior and cognitive impairment dependent on dsRNA length, IFNAR1 expression and age. Biorxiv : the Preprint Server For Biology. PMID 33442686 DOI: 10.1101/2021.01.09.426034  0.305
2019 Skelly DT, Griffin ÉW, Murray CL, Harney S, O'Boyle C, Hennessy E, Dansereau MA, Nazmi A, Tortorelli L, Rawlins JN, Bannerman DM, Cunningham C. Correction: Acute transient cognitive dysfunction and acute brain injury induced by systemic inflammation occur by dissociable IL-1-dependent mechanisms. Molecular Psychiatry. PMID 30890763 DOI: 10.1038/s41380-019-0403-7  0.367
2019 Nazmi A, Field RH, Griffin EW, Haugh O, Hennessy E, Cox D, Reis R, Tortorelli L, Murray CL, Lopez-Rodriguez AB, Jin L, Lavelle EC, Dunne A, Cunningham C. Chronic neurodegeneration induces type I interferon synthesis via STING, shaping microglial phenotype and accelerating disease progression. Glia. PMID 30680794 DOI: 10.1002/Glia.23592  0.357
2018 Skelly DT, Griffin ÉW, Murray CL, Harney S, O'Boyle C, Hennessy E, Dansereau MA, Nazmi A, Tortorelli L, Rawlins JN, Bannerman DM, Cunningham C. Acute transient cognitive dysfunction and acute brain injury induced by systemic inflammation occur by dissociable IL-1-dependent mechanisms. Molecular Psychiatry. PMID 29875474 DOI: 10.1038/S41380-018-0075-8  0.452
2018 Nolan A, Hennessy E, Krukowski K, Guglielmetti C, Chaumeil M, Sohal VS, Rosi S. Repeated mild head injury leads to wide ranging deficits in higher order cognitive functions associated with the prefrontal cortex. Journal of Neurotrauma. PMID 29732949 DOI: 10.1089/Neu.2018.5731  0.35
2017 Manso Y, Holland PR, Kitamura A, Szymkowiak S, Duncombe J, Hennessy E, Searcy JL, Marangoni M, Randall AD, Brown JT, McColl BW, Horsburgh K. Minocycline reduces microgliosis and improves subcortical white matter function in a model of cerebral vascular disease. Glia. PMID 28722234 DOI: 10.1002/Glia.23190  0.311
2016 Hennessy E, Gormley S, Belen Lopez-Rodriguez A, Murray C, Murray C, Cunningham C. Systemic TNF-α produces acute cognitive dysfunction and exaggerated sickness behavior when superimposed upon progressive neurodegeneration. Brain, Behavior, and Immunity. PMID 27633985 DOI: 10.1016/J.Bbi.2016.09.011  0.48
2016 McDonald CL, Hennessy E, Araiz AR, Keogh B, McCormack W, McGuirk P, Reilly M, Lynch MA. Inhibiting TLR2 activation attenuates amyloid accumulation and glial activation in a mouse model of Alzheimer's disease. Brain, Behavior, and Immunity. PMID 27422717 DOI: 10.1016/J.Bbi.2016.07.143  0.345
2015 Hennessy E, Griffin ÉW, Cunningham C. Astrocytes Are Primed by Chronic Neurodegeneration to Produce Exaggerated Chemokine and Cell Infiltration Responses to Acute Stimulation with the Cytokines IL-1β and TNF-α. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 8411-22. PMID 26041910 DOI: 10.1523/Jneurosci.2745-14.2015  0.474
2015 Cunningham C, Hennessy E. Co-morbidity and systemic inflammation as drivers of cognitive decline: new experimental models adopting a broader paradigm in dementia research. Alzheimer's Research & Therapy. 7: 33. PMID 25802557 DOI: 10.1186/S13195-015-0117-2  0.454
2015 Davis DH, Skelly DT, Murray C, Hennessy E, Bowen J, Norton S, Brayne C, Rahkonen T, Sulkava R, Sanderson DJ, Rawlins JN, Bannerman DM, MacLullich AM, Cunningham C. Worsening cognitive impairment and neurodegenerative pathology progressively increase risk for delirium. The American Journal of Geriatric Psychiatry : Official Journal of the American Association For Geriatric Psychiatry. 23: 403-15. PMID 25239680 DOI: 10.1016/J.Jagp.2014.08.005  0.368
2013 Skelly DT, Hennessy E, Dansereau MA, Cunningham C. A Systematic Analysis of the Peripheral and CNS Effects of Systemic LPS, IL-1Β, TNF-α and IL-6 Challenges in C57BL/6 Mice Plos One. 8. PMID 23840908 DOI: 10.1371/Journal.Pone.0069123  0.441
2013 Skelly DT, Hennessy E, Dansereau M, Cunningham C. Correction: A Systematic Analysis of the Peripheral and CNS Effects of Systemic LPS, IL-1β, TNF-α and IL-6 Challenges in C57BL/6 Mice Plos One. 8. DOI: 10.1371/Annotation/90C76048-2Edd-4315-8404-4D9D8Cbd411E  0.39
2010 Skelly D, Hennessy E, Cunningham C. A comparative study of CNS effects of LPS and pro-inflammatory cytokines Brain Behavior and Immunity. 24. DOI: 10.1016/J.Bbi.2010.07.188  0.359
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