Kelvin Y. Kwan - Publications

Affiliations: 
Rutgers University, New Brunswick/Piscataway, New Brunswick, NJ, United States 
Area:
Neuroscience, Stem Cells, Auditory System
Website:
https://sites.google.com/view/kwan-lab-rutgers/home

33 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Jin M, Xu R, Wang L, Alam MM, Ma Z, Zhu S, Martini AC, Jadali A, Bernabucci M, Xie P, Kwan KY, Pang ZP, Head E, Liu Y, Hart RP, et al. Type-I-interferon signaling drives microglial dysfunction and senescence in human iPSC models of Down syndrome and Alzheimer's disease. Cell Stem Cell. 29: 1135-1153.e8. PMID 35803230 DOI: 10.1016/j.stem.2022.06.007  0.756
2021 Kwan KY, White PM. Understanding the differentiation and epigenetics of cochlear sensory progenitors in pursuit of regeneration. Current Opinion in Otolaryngology & Head and Neck Surgery. PMID 34374667 DOI: 10.1097/MOO.0000000000000741  0.396
2020 Xu R, Li X, Boreland AJ, Posyton A, Kwan K, Hart RP, Jiang P. Human iPSC-derived mature microglia retain their identity and functionally integrate in the chimeric mouse brain. Nature Communications. 11: 1577. PMID 32221280 DOI: 10.1038/S41467-020-15411-9  0.328
2019 Rathnam C, Chueng SD, Ying YM, Lee KB, Kwan K. Developments in Bio-Inspired Nanomaterials for Therapeutic Delivery to Treat Hearing Loss. Frontiers in Cellular Neuroscience. 13: 493. PMID 31780898 DOI: 10.3389/Fncel.2019.00493  0.348
2019 Song Z, Laureano AS, Patel K, Yip S, Jadali A, Kwan KY. Single-Cell Fluorescence Analysis of Pseudotemporal Ordered Cells Provides Protein Expression Dynamics for Neuronal Differentiation. Frontiers in Cell and Developmental Biology. 7: 87. PMID 31192206 DOI: 10.3389/Fcell.2019.00087  0.743
2017 Li Y, Anderson J, Kwan KY, Cai L. Single-Cell Transcriptome Analysis of Neural Stem Cells. Current Pharmacology Reports. 3: 68-76. PMID 29862164 DOI: 10.1007/S40495-017-0084-3  0.418
2017 Song Z, Jadali A, Fritzsch B, Kwan KY. NEUROG1 Regulates CDK2 to Promote Proliferation in Otic Progenitors. Stem Cell Reports. PMID 29033307 DOI: 10.1016/J.Stemcr.2017.09.011  0.782
2017 Sun N, Nasello C, Deng L, Wang N, Zhang Y, Xu Z, Song Z, Kwan K, King RA, Pang ZP, Xing J, Heiman GA, Tischfield JA. The PNKD gene is associated with Tourette Disorder or Tic disorder in a multiplex family. Molecular Psychiatry. PMID 28894297 DOI: 10.1038/Mp.2017.179  0.746
2017 Ebeid M, Sripal P, Pecka J, Beisel KW, Kwan K, Soukup GA. Transcriptome-wide comparison of the impact of Atoh1 and miR-183 family on pluripotent stem cells and multipotent otic progenitor cells. Plos One. 12: e0180855. PMID 28686713 DOI: 10.1371/Journal.Pone.0180855  0.445
2017 Jadali A, Ying YM, Kwan KY. Activation of CHK1 in Supporting Cells Indirectly Promotes Hair Cell Survival. Frontiers in Cellular Neuroscience. 11: 137. PMID 28572758 DOI: 10.3389/Fncel.2017.00137  0.798
2016 Kwan KY. Single-Cell Transcriptome Analysis of Developing and Regenerating Spiral Ganglion Neurons. Current Pharmacology Reports. 2: 211-220. PMID 28758056 DOI: 10.1007/S40495-016-0064-Z  0.56
2016 Li Y, Tzatzalos E, Kwan KY, Grumet M, Cai L. Transcriptional Regulation of Notch1 Expression by Nkx6.1 in Neural Stem/Progenitor Cells during Ventral Spinal Cord Development. Scientific Reports. 6: 38665. PMID 27924849 DOI: 10.1038/Srep38665  0.41
2016 Vogl C, Panou I, Yamanbaeva G, Wichmann C, Mangosing SJ, Vilardi F, Indzhykulian AA, Pangršič T, Santarelli R, Rodriguez-Ballesteros M, Weber T, Jung S, Cardenas E, Wu X, Wojcik SM, ... Kwan KY, et al. Tryptophan-rich basic protein (WRB) mediates insertion of the tail-anchored protein otoferlin and is required for hair cell exocytosis and hearing. The Embo Journal. PMID 27458190 DOI: 10.15252/Embj.201593565  0.8
2016 Jadali A, Kwan KY. Activation of PI3K signaling prevents aminoglycoside-induced hair cell death in the murine cochlea. Biology Open. PMID 27142333 DOI: 10.1242/Bio.016758  0.792
2016 Azadeh J, Song Z, Laureano AS, Toro-Ramos A, Kwan K. Initiating Differentiation in Immortalized Multipotent Otic Progenitor Cells. Journal of Visualized Experiments : Jove. PMID 26780605 DOI: 10.3791/53692  0.76
2016 Azadeh J, Song Z, Laureano AS, Toro-Ramos A, Kwan K. Initiating differentiation in immortalized multipotent otic progenitor cells Journal of Visualized Experiments. 2016. DOI: 10.3791/53692  0.748
2015 Patel S, Chueng ST, Yin PT, Dardir K, Song Z, Pasquale N, Kwan K, Sugiyama H, Lee KB. Induction of Stem-Cell-Derived Functional Neurons by NanoScript-Based Gene Repression. Angewandte Chemie (International Ed. in English). 54: 11983-8. PMID 26292201 DOI: 10.1002/Anie.201504902  0.81
2015 Shen J, Scheffer DI, Kwan KY, Corey DP. SHIELD: an integrative gene expression database for inner ear research. Database : the Journal of Biological Databases and Curation. 2015: bav071. PMID 26209310 DOI: 10.1093/Database/Bav071  0.586
2015 Kwan KY, Shen J, Corey DP. C-MYC transcriptionally amplifies SOX2 target genes to regulate self-renewal in multipotent otic progenitor cells. Stem Cell Reports. 4: 47-60. PMID 25497456 DOI: 10.1016/J.Stemcr.2014.11.001  0.724
2014 Clarke ST, Song Z, Kwan KY, DeMarco C, Rukavishnikov A, Singh U, Gee K. Abstract 5098: GFP compatibility with EdU cell proliferation assay Cancer Research. 74: 5098-5098. DOI: 10.1158/1538-7445.Am2014-5098  0.783
2012 Shigetomi E, Tong X, Kwan KY, Corey DP, Khakh BS. TRPA1 channels regulate astrocyte resting calcium and inhibitory synapse efficacy through GAT-3. Nature Neuroscience. 15: 70-80. PMID 22158513 DOI: 10.1038/Nn.3000  0.547
2009 Brierley SM, Hughes PA, Page AJ, Kwan KY, Martin CM, O'Donnell TA, Cooper NJ, Harrington AM, Adam B, Liebregts T, Holtmann G, Corey DP, Rychkov GY, Blackshaw LA. The ion channel TRPA1 is required for normal mechanosensation and is modulated by algesic stimuli. Gastroenterology. 137: 2084-2095.e3. PMID 19632231 DOI: 10.1053/J.Gastro.2009.07.048  0.594
2009 Kwan KY, Glazer JM, Corey DP, Rice FL, Stucky CL. TRPA1 modulates mechanotransduction in cutaneous sensory neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 4808-19. PMID 19369549 DOI: 10.1523/Jneurosci.5380-08.2009  0.592
2009 Kwan KY, Corey DP. Burning cold: involvement of TRPA1 in noxious cold sensation. The Journal of General Physiology. 133: 251-6. PMID 19237590 DOI: 10.1085/Jgp.200810146  0.591
2009 Karashima Y, Talavera K, Everaerts W, Janssens A, Kwan KY, Vennekens R, Nilius B, Voets T. TRPA1 acts as a cold sensor in vitro and in vivo Proceedings of the National Academy of Sciences of the United States of America. 106: 1273-1278. PMID 19144922 DOI: 10.1073/Pnas.0808487106  0.336
2008 Brierley SM, Hughes PA, Page AJ, O'Donnell TA, Martin CM, Kwan KY, Corey DP, Blackshaw LA. 50 Novel and Specific Roles for the Ion Channel TRPA1 in Visceral Sensory Transduction Gastroenterology. 134: A-8. DOI: 10.1016/S0016-5085(08)60045-1  0.572
2007 Macpherson LJ, Xiao B, Kwan KY, Petrus MJ, Dubin AE, Hwang S, Cravatt B, Corey DP, Patapoutian A. An ion channel essential for sensing chemical damage. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 11412-5. PMID 17942735 DOI: 10.1523/Jneurosci.3600-07.2007  0.567
2007 Kwan KY, Greenwald RJ, Mohanty S, Sharpe AH, Shaw AC, Wang JC. Development of autoimmunity in mice lacking DNA topoisomerase 3β Proceedings of the National Academy of Sciences of the United States of America. 104: 9242-9247. PMID 17517607 DOI: 10.1073/Pnas.0703587104  0.466
2007 Vollrath MA, Kwan KY, Corey DP. The micromachinery of mechanotransduction in hair cells. Annual Review of Neuroscience. 30: 339-65. PMID 17428178 DOI: 10.1146/Annurev.Neuro.29.051605.112917  0.784
2006 Kwan KY, Allchorne AJ, Vollrath MA, Christensen AP, Zhang DS, Woolf CJ, Corey DP. TRPA1 contributes to cold, mechanical, and chemical nociception but is not essential for hair-cell transduction. Neuron. 50: 277-89. PMID 16630838 DOI: 10.1016/J.Neuron.2006.03.042  0.792
2004 Corey DP, García-Añoveros J, Holt JR, Kwan KY, Lin SY, Vollrath MA, Amalfitano A, Cheung EL, Derfler BH, Duggan A, Géléoc GS, Gray PA, Hoffman MP, Rehm HL, Tamasauskas D, et al. TRPA1 is a candidate for the mechanosensitive transduction channel of vertebrate hair cells. Nature. 432: 723-30. PMID 15483558 DOI: 10.1038/Nature03066  0.717
2003 Kwan KY, Moens PB, Wang JC. Infertility and aneuploidy in mice lacking a type IA DNA topoisomerase IIIβ Proceedings of the National Academy of Sciences of the United States of America. 100: 2526-2531. PMID 12591952 DOI: 10.1073/Pnas.0437998100  0.435
2001 Kwan KY, Wang JC. Mice lacking DNA topoisomerase III/β develop to maturity but show a reduced mean lifespan Proceedings of the National Academy of Sciences of the United States of America. 98: 5717-5721. PMID 11331780 DOI: 10.1073/Pnas.101132498  0.431
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