| Year |
Citation |
Score |
| 2023 |
Castro J, Maddern J, Chow CY, Tran P, Vetter I, King GF, Brierley SM. The voltage-gated sodium channel Na 1.7 underlies endometriosis-associated chronic pelvic pain. Journal of Neurochemistry. PMID 36840383 DOI: 10.1111/jnc.15795 |
0.3 |
|
| 2022 |
Grundy L, Tay C, Christie S, Harrington AM, Castro J, Cardoso FC, Lewis RJ, Zagorodnyuk V, Brierley SM. The T type calcium channel CaV3.2 regulates bladder afferent responses to mechanical stimuli. Pain. PMID 36279179 DOI: 10.1097/j.pain.0000000000002795 |
0.306 |
|
| 2022 |
Caldwell A, Grundy L, Harrington AM, Garcia-Caraballo S, Castro J, Bunnett NW, Brierley SM. TGR5 agonists induce peripheral and central hypersensitivity to bladder distension. Scientific Reports. 12: 9920. PMID 35705684 DOI: 10.1038/s41598-022-14195-w |
0.311 |
|
| 2021 |
Jiang Y, Castro J, Blomster LV, Agwa AJ, Maddern J, Schober G, Herzig V, Chow CY, Cardoso FC, Demétrio De Souza França P, Gonzales J, Schroeder CI, Esche S, Reiner T, Brierley SM, et al. Pharmacological Inhibition of the Voltage-Gated Sodium Channel Na1.7 Alleviates Chronic Visceral Pain in a Rodent Model of Irritable Bowel Syndrome. Acs Pharmacology & Translational Science. 4: 1362-1378. PMID 34423271 DOI: 10.1021/acsptsci.1c00072 |
0.302 |
|
| 2021 |
Brizuela M, Castro J, Harrington AM, Brierley SM. Pruritogenic mechanisms and gut sensation: putting the "irritant" into irritable bowel syndrome. American Journal of Physiology. Gastrointestinal and Liver Physiology. 320: G1131-G1141. PMID 33949199 DOI: 10.1152/ajpgi.00331.2020 |
0.354 |
|
| 2021 |
Grundy L, Caldwell A, Garcia-Caraballo S, Grundy D, Spencer NJ, Dong X, Castro J, Harrington AM, Brierley SM. Activation of MrgprA3 and MrgprC11 on bladder-innervating afferents induces peripheral and central hypersensitivity to bladder distension. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 33727332 DOI: 10.1523/JNEUROSCI.0033-21.2021 |
0.345 |
|
| 2020 |
Cardoso FC, Castro J, Grundy L, Schober G, Garcia-Caraballo S, Zhao T, Herzig V, King GF, Brierley SM, Lewis RJ. A spider-venom peptide with multi-target activity on sodium and calcium channels alleviates chronic visceral pain in a model of irritable bowel syndrome. Pain. PMID 32826759 DOI: 10.1097/J.Pain.0000000000002041 |
0.415 |
|
| 2020 |
Castro J, Maddern J, Erickson A, Caldwell A, Grundy L, Harrington AM, Brierley SM. Pharmacological modulation of voltage-gated sodium (NaV) channels alters nociception arising from the female reproductive tract. Pain. PMID 32826751 DOI: 10.1097/J.Pain.0000000000002036 |
0.423 |
|
| 2020 |
Tsukimi Y, Pustovit RV, Harrington AM, Garcia-Caraballo S, Brierley SM, Di Natale M, Molero JC, Furness JB. Effects and sites of action of a M1 receptor positive allosteric modulator on colonic motility in rats and dogs compared with 5-HT agonism and cholinesterase inhibition. Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society. e13866. PMID 32337809 DOI: 10.1111/Nmo.13866 |
0.319 |
|
| 2020 |
Morrie RD, Bayrer J, Brierley S, Ingraham H, Julius D. SPARC ‐ Mapping Gut‐Spinal Cord Connections in Visceral Pain The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.06185 |
0.311 |
|
| 2020 |
Harrington A, Garcia-Caraballo S, Grundy L, Castro J, Hannig G, Brierley S. Mo1146 CHRONIC INTRA-COLONIC LINACLOTIDE ADMINISTRATION ALTERS GLIAL ACTIVATION IN A MOUSE MODEL OF CHRONIC VISCERAL HYPERSENSITIVITY Gastroenterology. 158: S-803. DOI: 10.1016/S0016-5085(20)32687-1 |
0.304 |
|
| 2020 |
Castro J, Maddern J, Garcia-Caraballo S, Schober G, Lindstrom B, Schmiel S, Brierley S. Sa1078 CANNABINOID RECEPTOR EXPRESSION AND THE EFFECT OF OLORINAB, A PERIPHERALLY ACTING, HIGHLY SELECTIVE, FULL AGONIST OF THE CANNABINOID RECEPTOR 2 (CB2), IN RODENTS WITH COLITIS AND CHRONIC VISCERAL HYPERSENSITIVITY Gastroenterology. 158: S-269. DOI: 10.1016/S0016-5085(20)31353-6 |
0.349 |
|
| 2019 |
Grundy L, Caldwell A, Garcia Caraballo S, Erickson A, Schober G, Castro J, Harrington AM, Brierley SM. Histamine induces peripheral and central hypersensitivity to bladder distension via the histamine H receptor and TRPV1. American Journal of Physiology. Renal Physiology. PMID 31790304 DOI: 10.1152/Ajprenal.00435.2019 |
0.449 |
|
| 2019 |
Chess-Williams R, Sellers DJ, Brierley SM, Grundy D, Grundy L. Purinergic receptor mediated calcium signalling in urothelial cells. Scientific Reports. 9: 16101. PMID 31695098 DOI: 10.1038/S41598-019-52531-9 |
0.307 |
|
| 2019 |
Castro J, Harrington AM, Lieu T, Garcia-Caraballo S, Maddern J, Schober G, O'Donnell T, Grundy L, Lumsden AL, Miller PE, Ghetti A, Steinhoff MS, Poole DP, Dong X, Chang L, ... ... Brierley SM, et al. Activation of pruritogenic TGR5, MRGPRA3, and MRGPRC11 on colon-innervating afferents induces visceral hypersensitivity. Jci Insight. PMID 31536477 DOI: 10.1172/Jci.Insight.131712 |
0.473 |
|
| 2019 |
Konthapakdee N, Grundy L, O'Donnell T, Garcia-Caraballo S, Brierley SM, Grundy D, Daly DM. Serotonin exerts a direct modulatory role on bladder afferent firing in mice. The Journal of Physiology. PMID 31520534 DOI: 10.1113/Jp278751 |
0.365 |
|
| 2019 |
Brierley SM, Goh KGK, Sullivan MJ, Moore KH, Ulett GC, Grundy L. Innate immune response to bacterial urinary tract infection sensitises high-threshold bladder afferents and recruits silent nociceptors. Pain. PMID 31479069 DOI: 10.1097/J.Pain.0000000000001692 |
0.367 |
|
| 2019 |
Ge P, Ren J, Harrington AM, Grundy L, Castro J, Brierley SM, Hannig G. Linaclotide treatment reduces endometriosis-associated vaginal hyperalgesia and mechanical allodynia through viscero-visceral cross-talk. Pain. PMID 31335750 DOI: 10.1097/J.Pain.0000000000001657 |
0.426 |
|
| 2019 |
Harrington AM, Garcia Caraballo S, Maddern JE, Grundy L, Castro J, Brierley SM. Colonic afferent input and dorsal horn neuron activation differs between the thoracolumbar and lumbosacral spinal cord. American Journal of Physiology. Gastrointestinal and Liver Physiology. PMID 31188624 DOI: 10.1152/Ajpgi.00013.2019 |
0.342 |
|
| 2019 |
Israel MR, Tanaka BS, Castro J, Thongyoo P, Robinson SD, Zhao P, Deuis JR, Craik DJ, Durek T, Brierley SM, Waxman SG, Dib-Hajj SD, Vetter I. Na 1.6 regulates excitability of mechanosensitive sensory neurons. The Journal of Physiology. PMID 31087362 DOI: 10.1113/Jp278148 |
0.389 |
|
| 2019 |
Grundy* L, Harrington A, Caldwell A, Castro J, Zagorodnyuk V, Brookes S, Spencer N, Brierley S. PD14-05 LOW AND HIGH THRESHOLD MECHANOSENSITIVE BLADDER AFFERENT PATHWAYS CONVERGE TO A SIMILAR DISTRIBUTION OF LUMBOSACRAL SPINAL NEURONS Journal of Urology. 201. DOI: 10.1097/01.Ju.0000555474.19797.83 |
0.314 |
|
| 2019 |
Lindstrom BF, Ruckle JL, Turner SA, Stauber K, Brierley SM, English BA, Yacyshyn B. P139 OLORINAB, A PERIPHERALLY RESTRICTED, HIGHLY SELECTIVE AGONIST OF THE CANNABINOID RECEPTOR TYPE 2 FOR THE MANAGEMENT OF VISCERAL PAIN IN INFLAMMATORY BOWEL DISEASE (IBD) – PRECLINICAL AND EARLY CLINICAL DEVELOPMENT Gastroenterology. 156: S92-S93. DOI: 10.1053/J.Gastro.2019.01.215 |
0.358 |
|
| 2019 |
Castro J, Harrington A, Maddern J, Schober G, Grundy LA, Ge P, Hannig G, Brierley S. Su1578 – Chronic Intracolonic Administration of Linaclotide Inhibits Nociceptive Signaling in a Mouse Model of Chronic Visceral Hypersensitivity Gastroenterology. 156: S-570. DOI: 10.1016/S0016-5085(19)38317-9 |
0.301 |
|
| 2019 |
Castro J, Maddern J, Garcia-Caraballo S, Lumsden AL, Lindstrom B, Adams J, Brierley S. Sa1738 – Olorinab (Formerly Apd371), a Peripherally Restricted, Highly Selective, Full Agonist of the Cannabinoid Receptor 2 (CB2), Reduces Visceral Hypersensitivity in Animal Models Gastroenterology. 156: S-382. DOI: 10.1016/S0016-5085(19)37805-9 |
0.307 |
|
| 2018 |
Grundy L, Caldwell A, Brierley SM. Mechanisms Underlying Overactive Bladder and Interstitial Cystitis/Painful Bladder Syndrome. Frontiers in Neuroscience. 12: 931. PMID 30618560 DOI: 10.3389/Fnins.2018.00931 |
0.391 |
|
| 2018 |
Brierley SM, Hibberd TJ, Spencer NJ. Spinal Afferent Innervation of the Colon and Rectum. Frontiers in Cellular Neuroscience. 12: 467. PMID 30564102 DOI: 10.3389/Fncel.2018.00467 |
0.382 |
|
| 2018 |
Grundy L, Harrington AM, Caldwell A, Castro J, Staikopoulos V, Zagorodnyuk VP, Brookes SJH, Spencer NJ, Brierley SM. Translating peripheral bladder afferent mechanosensitivity to neuronal activation within the lumbosacral spinal cord of mice. Pain. PMID 30531372 DOI: 10.1097/J.Pain.0000000000001453 |
0.341 |
|
| 2018 |
Grundy L, Harrington AM, Castro J, Garcia-Caraballo S, Deiteren A, Maddern J, Rychkov GY, Ge P, Peters S, Feil R, Miller P, Ghetti A, Hannig G, Kurtz CB, Silos-Santiago I, ... Brierley SM, et al. Chronic linaclotide treatment reduces colitis-induced neuroplasticity and reverses persistent bladder dysfunction. Jci Insight. 3. PMID 30282832 DOI: 10.1172/Jci.Insight.121841 |
0.434 |
|
| 2018 |
Grundy L, Erickson A, Caldwell A, Garcia-Caraballo S, Rychkov G, Harrington A, Brierley SM. Tetrodotoxin-sensitive voltage-gated sodium channels regulate bladder afferent responses to distension. Pain. PMID 30157135 DOI: 10.1097/J.Pain.0000000000001368 |
0.387 |
|
| 2018 |
Jimenez-Vargas NN, Pattison LA, Zhao P, Lieu T, Latorre R, Jensen DD, Castro J, Aurelio L, Le GT, Flynn B, Herenbrink CK, Yeatman HR, Edgington-Mitchell L, Porter CJH, Halls ML, ... ... Brierley SM, et al. Protease-activated receptor-2 in endosomes signals persistent pain of irritable bowel syndrome. Proceedings of the National Academy of Sciences of the United States of America. PMID 30012612 DOI: 10.1073/Pnas.1721891115 |
0.411 |
|
| 2018 |
Grundy L, Chess-Williams R, Brierley SM, Mills K, Moore KH, Mansfield K, Rose'Meyer R, Sellers DJ, Grundy D. NKA enhances bladder afferent mechanosensitivity via urothelial and detrusor activation. American Journal of Physiology. Renal Physiology. PMID 29897284 DOI: 10.1152/Ajprenal.00106.2018 |
0.397 |
|
| 2018 |
Salvatierra J, Castro J, Erickson A, Li Q, Braz J, Gilchrist J, Grundy L, Rychkov GY, Deiteren A, Rais R, King GF, Slusher BS, Basbaum A, Pasricha PJ, Brierley SM, et al. NaV1.1 inhibition can reduce visceral hypersensitivity. Jci Insight. 3. PMID 29875317 DOI: 10.1172/Jci.Insight.121000 |
0.452 |
|
| 2018 |
Sadeghi M, Carstens BB, Callaghan BP, Daniel JT, Tae HS, O'Donnell T, Castro J, Brierley SM, Adams DJ, Craik DJ, Clark RJ. Structure-activity studies reveal the molecular basis for GABAB-receptor mediated inhibition of high voltage-activated calcium channels by α-conotoxin Vc1.1. Acs Chemical Biology. PMID 29746088 DOI: 10.1021/Acschembio.8B00190 |
0.509 |
|
| 2018 |
Guerrero-Alba R, Valdez-Morales EE, Jiménez-Vargas NN, Bron R, Poole D, Reed D, Castro J, Campaniello M, Hughes PA, Brierley SM, Bunnett N, Lomax AE, Vanner S. CO-EXPRESSION OF μ AND ∂ OPIOID RECEPTORS BY MOUSE COLONIC NOCICEPTORS. British Journal of Pharmacology. PMID 29579315 DOI: 10.1111/Bph.14222 |
0.342 |
|
| 2018 |
Desormeaux C, Bautzova T, Garcia-Caraballo S, Rolland C, Barbaro MR, Brierley SM, Barbara G, Vergnolle N, Cenac N. Protease-Activated Receptor 1 is Implicated in Irritable Bowel Syndrome Mediators-Induced Signalling to Thoracic Human Sensory Neurons. Pain. PMID 29554016 DOI: 10.1097/J.Pain.0000000000001208 |
0.371 |
|
| 2018 |
Sadeghi M, Erickson A, Castro J, Deiteren A, Harrington AM, Grundy L, Adams DJ, Brierley SM. Contribution of membrane receptor signalling to chronic visceral pain. The International Journal of Biochemistry & Cell Biology. PMID 29477359 DOI: 10.1016/J.Biocel.2018.02.017 |
0.537 |
|
| 2018 |
Erickson A, Deiteren A, Harrington AM, Garcia-Caraballo S, Castro J, Caldwell A, Grundy L, Brierley SM. Voltage-gated sodium channels: (NaV )igating the field to determine their contribution to visceral nociception. The Journal of Physiology. PMID 29318638 DOI: 10.1113/Jp273461 |
0.391 |
|
| 2017 |
Jami S, Erickson A, Brierley SM, Vetter I. Pain-Causing Venom Peptides: Insights into Sensory Neuron Pharmacology. Toxins. 10. PMID 29280959 DOI: 10.3390/Toxins10010015 |
0.382 |
|
| 2017 |
Castro J, Grundy L, Deiteren A, Harrington AM, O'Donnell T, Maddern J, Moore J, Garcia-Caraballo S, Rychkov GY, Yu R, Kaas Q, Craik DJ, Adams DJ, Brierley SM. Cyclic analogues of α-conotoxin Vc1.1 inhibit colonic nociceptors and provide analgesia in a mouse model of chronic abdominal pain. British Journal of Pharmacology. PMID 29194563 DOI: 10.1111/Bph.14115 |
0.526 |
|
| 2017 |
Spencer NJ, Greenheigh S, Kyloh M, Hibberd TJ, Sharma H, Grundy L, Brierley SM, Harrington AM, Beckett EA, Brookes SJ, Zagorodnyuk VP. Identifying unique subtypes of spinal afferent nerve endings within the urinary bladder of mice. The Journal of Comparative Neurology. PMID 29178500 DOI: 10.1002/Cne.24362 |
0.341 |
|
| 2017 |
Grundy L, Brierley SM. Cross-organ sensitisation between the colon and bladder: To pee, or not to pee? American Journal of Physiology. Gastrointestinal and Liver Physiology. ajpgi.00272.2017. PMID 29146678 DOI: 10.1152/Ajpgi.00272.2017 |
0.389 |
|
| 2017 |
Bellono NW, Bayrer JR, Leitch DB, Castro J, Zhang C, O'Donnell TA, Brierley SM, Ingraham HA, Julius D. Enterochromaffin Cells Are Gut Chemosensors that Couple to Sensory Neural Pathways. Cell. PMID 28648659 DOI: 10.1016/J.Cell.2017.05.034 |
0.323 |
|
| 2017 |
Lee MC, McCubbin JA, Christensen AD, Poole DP, Rajasekhar P, Lieu T, Bunnett NW, Garcia-Caraballo S, Erickson A, Brierley SM, Saleh R, Achuthan A, Fleetwood AJ, Anderson RL, Hamilton JA, et al. G-CSF Receptor Blockade Ameliorates Arthritic Pain and Disease. Journal of Immunology (Baltimore, Md. : 1950). PMID 28320832 DOI: 10.4049/Jimmunol.1602127 |
0.363 |
|
| 2017 |
Inserra MC, Israel MR, Caldwell A, Castro J, Deuis JR, Harrington AM, Keramidas A, Garcia-Caraballo S, Maddern J, Erickson A, Grundy L, Rychkov GY, Zimmermann K, Lewis RJ, Brierley SM, et al. Multiple sodium channel isoforms mediate the pathological effects of Pacific ciguatoxin-1. Scientific Reports. 7: 42810. PMID 28225079 DOI: 10.1038/Srep42810 |
0.382 |
|
| 2017 |
Wan J, Mobli M, Brust A, Muttenthaler M, Andersson Å, Ragnarsson L, Castro J, Vetter I, Huang JX, Nilsson M, Brierley SM, Cooper MA, Lewis RJ, Alewood PF. Synthesis of Multivalent [Lys8]-Oxytocin Dendrimers that Inhibit Visceral Nociceptive Responses Australian Journal of Chemistry. 70: 162. DOI: 10.1071/Ch16407 |
0.342 |
|
| 2017 |
Castro J, Deiteren A, Harrington A, Maddern J, Moore J, Garcia-Caraballo S, O'Donnell T, Grundy LA, Hannig G, Kurtz C, Silos-Santiago A, Brierley S. Chronic Oral Administration of Linaclotide Inhibits Nociceptive Signalling in Response to Noxious Colorectal Distension in a Model of Chronic Visceral Hypersensitivity Gastroenterology. 152: S204. DOI: 10.1016/S0016-5085(17)30989-7 |
0.319 |
|
| 2017 |
Grundy LA, Castro J, Harrington A, Peters S, Feil R, Miller P, Ghetti A, Hannig G, Kurtz C, Silos-Santiago A, Brierley S. Extracellular CGMP Reduces the Excitability of Sensory Dorsal Root Ganglion Neurons via an Extracellular Mechanism Gastroenterology. 152: S156. DOI: 10.1016/S0016-5085(17)30847-8 |
0.338 |
|
| 2017 |
Grundy L, Garcia-Caraballo S, Maddern J, Rychkov G, Ge P, Hannig G, Kurtz C, Silos-Santiago A, Brierley S. MP42-05 CHRONIC ORAL ADMINISTRATION OF THE GUANYLATE CYCLASE-C AGONIST LINACLOTIDE ATTENUATES COLITIS INDUCED BLADDER AFFERENT AND DORSAL ROOT GANGLION HYPERACTIVITY Journal of Urology. 197. DOI: 10.1016/J.Juro.2017.02.1294 |
0.355 |
|
| 2016 |
Campaniello MA, Mavrangelos C, Eade S, Harrington AM, Ashley Blackshaw L, Brierley SM, Smid SD, Hughes PA. Acute colitis chronically alters immune infiltration mechanisms and sensory neuro-immune interactions. Brain, Behavior, and Immunity. PMID 27864046 DOI: 10.1016/J.Bbi.2016.11.015 |
0.349 |
|
| 2016 |
Brierley S. Altered Ion Channel/Receptor Expression and Function in Extrinsic Sensory Neurons: The Cause of and Solution to Chronic Visceral Pain? Advances in Experimental Medicine and Biology. 891: 75-90. PMID 27379637 DOI: 10.1007/978-3-319-27592-5_9 |
0.432 |
|
| 2016 |
Osteen JD, Herzig V, Gilchrist J, Emrick JJ, Zhang C, Wang X, Castro J, Garcia-Caraballo S, Grundy L, Rychkov GY, Weyer AD, Dekan Z, Undheim EA, Alewood P, Stucky CL, ... Brierley SM, et al. Selective spider toxins reveal a role for the Nav1.1 channel in mechanical pain. Nature. PMID 27281198 DOI: 10.1038/Nature17976 |
0.421 |
|
| 2016 |
Carstens BB, Berecki G, Daniel JT, Lee HS, Jackson KA, Tae HS, Sadeghi M, Castro J, O'Donnell T, Deiteren A, Brierley SM, Craik DJ, Adams DJ, Clark RJ. Structure-Activity Studies of Cysteine-Rich α-Conotoxins that Inhibit High Voltage-Activated Calcium Channels via GABAB Receptor Activation Reveal a Minimal Functional Motif. Angewandte Chemie (International Ed. in English). PMID 26948522 DOI: 10.1002/Anie.201600297 |
0.449 |
|
| 2016 |
Castro J, Harrington AM, Garcia-Caraballo S, Maddern J, Grundy L, Zhang J, Page G, Miller PE, Craik DJ, Adams DJ, Brierley SM. α-Conotoxin Vc1.1 inhibits human dorsal root ganglion neuroexcitability and mouse colonic nociception via GABAB receptors. Gut. PMID 26887818 DOI: 10.1136/Gutjnl-2015-310971 |
0.503 |
|
| 2016 |
Brust A, Croker DE, Colless B, Ragnarsson L, Andersson A, Jain K, Caraballo SG, Castro J, Brierley SM, Alewood PF, Lewis RJ. Conopeptide-derived κ-opioid agonists (conorphins): potent, selective and metabolic stable dynorphinA mimetics with anti-nociceptive properties. Journal of Medicinal Chemistry. PMID 26859603 DOI: 10.1021/Acs.Jmedchem.5B00911 |
0.332 |
|
| 2016 |
Grundy LA, Garcia-Carraballo S, Maddern J, Rychkov G, Hannig G, Kurtz CB, Silos-Santiago A, Brierley S. 561 Chronic Oral Administration of the Guanylate Cyclase-C Agonist Linaclotide Attenuates Colitis Induced Bladder Afferent Hyperactivity Gastroenterology. 150: S118-S119. DOI: 10.1016/S0016-5085(16)30506-6 |
0.338 |
|
| 2015 |
Campaniello MA, Harrington AM, Martin CM, Ashley Blackshaw L, Brierley SM, Hughes PA. Activation of colo-rectal high-threshold afferent nerves by Interleukin-2 is tetrodotoxin-sensitive and upregulated in a mouse model of chronic visceral hypersensitivity. Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society. PMID 26468044 DOI: 10.1111/Nmo.12696 |
0.363 |
|
| 2015 |
Castro J, Harrington AM, Lieu T, Garcia-Caraballo S, Maddern J, O'Donnell T, Grundy L, Poole DP, Bunnett NW, Brierley SM. Mo1876 A Visceral Representation of Itch: Identification ‘Itch-Specific’ Pruritogenic Mechanisms Within Colonic Sensory Pathways Gastroenterology. 148: S-733. DOI: 10.1016/S0016-5085(15)32505-1 |
0.318 |
|
| 2015 |
Castro J, Harrington AM, Garcia-Caraballo S, Maddern J, O'Donnell T, Grundy L, Kurtz CB, Silos-Santiago A, Brierley SM. 1028 Chronic Activation of the GC-C/cGMP Pathway by Linaclotide Inhibits Ascending Nociceptive Pathways and Restores Aberrant Spinal Cord Signaling Gastroenterology. 148: S-194. DOI: 10.1016/S0016-5085(15)30645-4 |
0.309 |
|
| 2014 |
Hughes PA, Moretta M, Lim A, Grasby DJ, Bird D, Brierley SM, Liebregts T, Adam B, Blackshaw LA, Holtmann G, Bampton P, Hoffmann P, Andrews JM, Zola H, Krumbiegel D. Immune derived opioidergic inhibition of viscerosensory afferents is decreased in Irritable Bowel Syndrome patients. Brain, Behavior, and Immunity. 42: 191-203. PMID 25063707 DOI: 10.1016/J.Bbi.2014.07.001 |
0.36 |
|
| 2014 |
Malsch P, Andratsch M, Vogl C, Link AS, Alzheimer C, Brierley SM, Hughes PA, Kress M. Deletion of interleukin-6 signal transducer gp130 in small sensory neurons attenuates mechanonociception and down-regulates TRPA1 expression. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 9845-56. PMID 25057188 DOI: 10.1523/Jneurosci.5161-13.2014 |
0.369 |
|
| 2014 |
Brierley SM, Linden DR. Neuroplasticity and dysfunction after gastrointestinal inflammation. Nature Reviews. Gastroenterology & Hepatology. 11: 611-27. PMID 25001973 DOI: 10.1038/Nrgastro.2014.103 |
0.362 |
|
| 2014 |
de Araujo AD, Mobli M, Castro J, Harrington AM, Vetter I, Dekan Z, Muttenthaler M, Wan J, Lewis RJ, King GF, Brierley SM, Alewood PF. Selenoether oxytocin analogues have analgesic properties in a mouse model of chronic abdominal pain. Nature Communications. 5: 3165. PMID 24476666 DOI: 10.1038/Ncomms4165 |
0.372 |
|
| 2014 |
Hughes PA, Castro J, Harrington AM, Isaacs N, Moretta M, Hicks GA, Urso DM, Brierley SM. Increased κ-opioid receptor expression and function during chronic visceral hypersensitivity. Gut. 63: 1199-200. PMID 24285775 DOI: 10.1136/Gutjnl-2013-306240 |
0.405 |
|
| 2014 |
Castro J, Rychkov GY, Ghetti A, Harrington AM, Kurtz CB, Silos-Santiago I, Brierley SM. Mo2029 Extracellular Cyclic GMP (cGMP), the Downstream Mediator Released in Response to Linaclotide-Induced Activation of Guanylate Cyclase-C (GC-C), Reduces Excitability of Murine and Human Dorsal Root Ganglion (DRG) Neurons Gastroenterology. 146: S-722. DOI: 10.1016/S0016-5085(14)62618-4 |
0.374 |
|
| 2014 |
Harrington AM, Castro J, Garcia-Caraballo S, Maddern J, Craik D, Adams DJ, Brierley SM. 888 α-Conotoxin Vc1.1 Targets GABAB Receptors Modulating CaV2.2 and CaV2.3 Calcium Channels in Sensory Pathways Mediating Chronic Visceral Pain Gastroenterology. 146: S-156. DOI: 10.1016/S0016-5085(14)60555-2 |
0.505 |
|
| 2013 |
Castro J, Harrington AM, Hughes PA, Martin CM, Ge P, Shea CM, Jin H, Jacobson S, Hannig G, Mann E, Cohen MB, MacDougall JE, Lavins BJ, Kurtz CB, Silos-Santiago I, ... ... Brierley SM, et al. Linaclotide inhibits colonic nociceptors and relieves abdominal pain via guanylate cyclase-C and extracellular cyclic guanosine 3',5'-monophosphate. Gastroenterology. 145: 1334-46.e1-11. PMID 23958540 DOI: 10.1053/J.Gastro.2013.08.017 |
0.425 |
|
| 2013 |
Blackshaw LA, Brierley SM. Emerging receptor target in the pharmacotherapy of irritable bowel syndrome with constipation. Expert Review of Gastroenterology & Hepatology. 7: 15-9. PMID 23859756 DOI: 10.1586/17474124.2013.820045 |
0.384 |
|
| 2013 |
Kentish SJ, O'Donnell TA, Isaacs NJ, Young RL, Li H, Harrington AM, Brierley SM, Wittert GA, Blackshaw LA, Page AJ. Gastric vagal afferent modulation by leptin is influenced by food intake status. The Journal of Physiology. 591: 1921-34. PMID 23266933 DOI: 10.1113/Jphysiol.2012.247577 |
0.315 |
|
| 2013 |
Hughes PA, Harrington AM, Castro J, Liebregts T, Adam B, Grasby DJ, Isaacs NJ, Maldeniya L, Martin CM, Persson J, Andrews JM, Holtmann G, Blackshaw LA, Brierley SM. Sensory neuro-immune interactions differ between irritable bowel syndrome subtypes. Gut. 62: 1456-65. PMID 22767422 DOI: 10.1136/Gutjnl-2011-301856 |
0.301 |
|
| 2013 |
Blackshaw LA, Brierley SM, Harrington AM, Hughes PA. TRP channels in visceral pain Open Pain Journal. 6: 23-30. DOI: 10.2174/1876386301306010023 |
0.436 |
|
| 2013 |
Castro J, Harrington AM, Mann E, Cohen MB, Kurtz C, Silos-Santiago A, Brierley SM. Mechanisms of linaclotide-induced inhibition of colonic nociception Neurogastroenterology and Motility. DOI: 10.1111/Nmo.12186 |
0.315 |
|
| 2013 |
Hughes PA, Harrington AM, Castro J, Isaacs NJ, Moretta M, Hicks GA, Urso DM, Brierley SM. Tu2119 Increased Efficacy of the Peripherally-Restricted Selective Kappa-Opioid Receptor Agonist, Asimadoline, in Chronic Visceral Hypersensitivity Gastroenterology. 144: S-934-S-935. DOI: 10.1016/S0016-5085(13)63474-5 |
0.317 |
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| 2013 |
Castro J, Harrington AM, Mann EA, Cohen MB, Kurtz CB, Silos-Santiago A, Brierley SM. 743 Mechanisms Underlying Linaclotide Induced Inhibition of Colonic Nociception Gastroenterology. 144: S-134. DOI: 10.1016/S0016-5085(13)60483-7 |
0.317 |
|
| 2012 |
Brierley SM. Guanylate cyclase-C receptor activation: unexpected biology. Current Opinion in Pharmacology. 12: 632-40. PMID 23131468 DOI: 10.1016/J.Coph.2012.10.005 |
0.342 |
|
| 2012 |
Harrington AM, Brierley SM, Isaacs N, Hughes PA, Castro J, Blackshaw LA. Sprouting of colonic afferent central terminals and increased spinal mitogen-activated protein kinase expression in a mouse model of chronic visceral hypersensitivity Journal of Comparative Neurology. 520: 2241-2255. PMID 22237807 DOI: 10.1002/Cne.23042 |
0.397 |
|
| 2012 |
Hughes PA, Isaacs NJ, Moretta M, Hicks GA, Urso DM, Blackshaw LA, Brierley SM. Mo1860 Identification of Kappa Opioid Receptors on Colonic Sensory Nerves and Their Up-Regulation in a Mouse Model of Chronic Visceral Hypersensitivity Gastroenterology. 142: S-702. DOI: 10.1016/S0016-5085(12)62712-7 |
0.463 |
|
| 2012 |
Castro J, Harrington AM, Hughes PA, Martin C, Silos-Santiago A, Kurtz CB, Blackshaw LA, Brierley SM. Mo1849 Mechanism of Action for Linaclotide Induced Abdominal Pain Relief Gastroenterology. 142: S-699. DOI: 10.1016/S0016-5085(12)62701-2 |
0.405 |
|
| 2012 |
Harrington AM, Brierley SM, Castro J, Isaacs NJ, Blackshaw LA. Mo1848 Characterization of Dorsal Horn Neurons Activated by Noxious Colorectal Distension in Health and Chronic Visceral Hypersensitivity Gastroenterology. 142: S-699. DOI: 10.1016/S0016-5085(12)62700-0 |
0.354 |
|
| 2011 |
Brierley SM, Kelber O. Use of natural products in gastrointestinal therapies. Current Opinion in Pharmacology. 11: 604-11. PMID 21996284 DOI: 10.1016/J.Coph.2011.09.007 |
0.331 |
|
| 2011 |
Brierley SM, Castro J, Harrington AM, Hughes PA, Page AJ, Rychkov GY, Blackshaw LA. TRPA1 contributes to specific mechanically activated currents and sensory neuron mechanical hypersensitivity Journal of Physiology. 589: 3575-3593. PMID 21558163 DOI: 10.1113/Jphysiol.2011.206789 |
0.395 |
|
| 2011 |
Harrington AM, Hughes PA, Martin CM, Yang J, Castro J, Isaacs NJ, Ashley Blackshaw L, Brierley SM. A novel role for TRPM8 in visceral afferent function Pain. 152: 1459-1468. PMID 21489690 DOI: 10.1016/J.Pain.2011.01.027 |
0.442 |
|
| 2011 |
Liebregts T, Adam B, Bredack C, Gururatsakul M, Pilkington KR, Brierley SM, Blackshaw LA, Gerken G, Talley NJ, Holtmann G. Small bowel homing T cells are associated with symptoms and delayed gastric emptying in functional dyspepsia. The American Journal of Gastroenterology. 106: 1089-98. PMID 21245834 DOI: 10.1016/S0016-5085(11)60565-9 |
0.304 |
|
| 2011 |
Hughes PA, Brierley SM, Martin CM. Post-inflammatory colonic afferent sensitisation: Different subtypes, different pathways and different time courses (Gut (2009) 58, (1333-1341)) Gut. 60: 140. DOI: 10.1136/Gut.2008.170811Corr1 |
0.302 |
|
| 2011 |
Hughes PA, Harrington A, Brierley SM, Maldeniya L, Martin C, Persson J, Liebregts T, Adam B, Holtmann G, Andrews JM, Blackshaw LA. Cytokine Modulation of Visceral Afferents via Cation Channels is Switched in Chronic Visceral Hypersensitivity Gastroenterology. 140: S-131. DOI: 10.1016/S0016-5085(11)60534-9 |
0.318 |
|
| 2011 |
Harrington A, Brierley SM, Castro J, Hughes PA, Blackshaw LA. Identification of Colonic Afferent Central Terminals and Changes Following Colonic Inflammation Gastroenterology. 140: S-131. DOI: 10.1016/S0016-5085(11)60533-7 |
0.316 |
|
| 2010 |
Brierley SM, Hughes PA, Harrington AM, Rychkov GY, Blackshaw LA. Identifying the Ion Channels Responsible for Signaling Gastro-Intestinal Based Pain. Pharmaceuticals (Basel, Switzerland). 3: 2768-2798. PMID 27713376 DOI: 10.3390/Ph3092768 |
0.377 |
|
| 2010 |
Brierley SM. Visualising vagal afferent neurons and their terminals whilst silencing TRPV1. The Journal of Physiology. 588: 4069-70. PMID 21037315 DOI: 10.1113/Jphysiol.2010.199711 |
0.361 |
|
| 2010 |
Brierley SM. All ahead stop! How intestinal motility adapts to cope with inflammation induced ulceration. The Journal of Physiology. 588: 753-4. PMID 20194135 DOI: 10.1113/Jphysiol.2010.187898 |
0.363 |
|
| 2010 |
Blackshaw LA, Brierley SM, Hughes PA. TRP channels: New targets for visceral pain Gut. 59: 126-135. PMID 20007960 DOI: 10.1136/Gut.2009.179523 |
0.413 |
|
| 2010 |
Brierley SM. Molecular basis of mechanosensitivity. Autonomic Neuroscience : Basic & Clinical. 153: 58-68. PMID 19683967 DOI: 10.1016/J.Autneu.2009.07.017 |
0.359 |
|
| 2010 |
Hughes PA, Brierley SM, Harrington AM, Castro J, Martin C, Blackshaw A. 942 Differential Coupling of Cytokine Receptors to Sensory Neurons in Health and Post Inflammation Gastroenterology. 138: S-136-S-137. DOI: 10.1016/S0016-5085(10)60626-9 |
0.33 |
|
| 2009 |
Brierley SM, Hughes PA, Page AJ, Kwan KY, Martin CM, O'Donnell TA, Cooper NJ, Harrington AM, Adam B, Liebregts T, Holtmann G, Corey DP, Rychkov GY, Blackshaw LA. The ion channel TRPA1 is required for normal mechanosensation and is modulated by algesic stimuli. Gastroenterology. 137: 2084-2095.e3. PMID 19632231 DOI: 10.1053/J.Gastro.2009.07.048 |
0.426 |
|
| 2009 |
Hughes PA, Brierley SM, Blackshaw LA. Post-inflammatory modification of colonic afferent mechanosensitivity Clinical and Experimental Pharmacology and Physiology. 36: 1034-1040. PMID 19566823 DOI: 10.1111/J.1440-1681.2009.05248.X |
0.393 |
|
| 2009 |
Hughes PA, Brierley SM, Martin CM, Brookes SJ, Linden DR, Blackshaw LA. Post-inflammatory colonic afferent sensitisation: different subtypes, different pathways and different time courses. Gut. 58: 1333-41. PMID 19324867 DOI: 10.1136/Gut.2008.170811 |
0.367 |
|
| 2009 |
Young RL, Sutherland K, Pezos N, Brierley SM, Horowitz M, Rayner CK, Blackshaw LA. Expression of taste molecules in the upper gastrointestinal tract in humans with and without type 2 diabetes. Gut. 58: 337-46. PMID 19039089 DOI: 10.1136/Gut.2008.148932 |
0.327 |
|
| 2009 |
Harrington AM, Hughes PA, Martin CM, Isaacs NJ, Brierley SM, Blackshaw LA. S5.5 Localisation and function of transient receptor potential ion channel melastatin subtype 8 (TRPM8) in mouse colonic primary afferent nerve fibres Autonomic Neuroscience: Basic and Clinical. 149: 29. DOI: 10.1016/J.Autneu.2009.05.028 |
0.339 |
|
| 2008 |
Brierley SM, Page AJ, Hughes PA, Adam B, Liebregts T, Cooper NJ, Holtmann G, Liedtke W, Blackshaw LA. Selective role for TRPV4 ion channels in visceral sensory pathways. Gastroenterology. 134: 2059-69. PMID 18343379 DOI: 10.1053/J.Gastro.2008.01.074 |
0.359 |
|
| 2008 |
Sipe WE, Brierley SM, Martin CM, Phillis BD, Cruz FB, Grady EF, Liedtke W, Cohen DM, Vanner S, Blackshaw LA, Bunnett NW. Transient receptor potential vanilloid 4 mediates protease activated receptor 2-induced sensitization of colonic afferent nerves and visceral hyperalgesia. American Journal of Physiology. Gastrointestinal and Liver Physiology. 294: G1288-98. PMID 18325985 DOI: 10.1152/Ajpgi.00002.2008 |
0.444 |
|
| 2008 |
Lindström E, Brusberg M, Hughes PA, Martin CM, Brierley SM, Phillis BD, Martinsson R, Abrahamsson C, Larsson H, Martinez V, Blackshaw LA. Involvement of metabotropic glutamate 5 receptor in visceral pain. Pain. 137: 295-305. PMID 17937975 DOI: 10.1016/J.Pain.2007.09.008 |
0.393 |
|
| 2008 |
Page AJ, O'Donnell TA, Koch L, Brierley SM, Blackshaw LA. 691 Switching of Leptin Effects On Peripheral Vagal Afferent Mechanosensitivity with Feeding and Fasting Gastroenterology. 134: A-97. DOI: 10.1016/S0016-5085(08)60453-9 |
0.352 |
|
| 2007 |
Page AJ, Slattery JA, Brierley SM, Jacoby AS, Blackshaw LA. Involvement of galanin receptors 1 and 2 in the modulation of mouse vagal afferent mechanosensitivity Journal of Physiology. 583: 675-684. PMID 17627995 DOI: 10.1113/Jphysiol.2007.135939 |
0.405 |
|
| 2007 |
Page AJ, Brierley SM, Martin CM, Hughes PA, Blackshaw LA. Acid sensing ion channels 2 and 3 are required for inhibition of visceral nociceptors by benzamil Pain. 133: 150-160. PMID 17467171 DOI: 10.1016/J.Pain.2007.03.019 |
0.436 |
|
| 2007 |
Page AJ, Slattery JA, Milte C, Laker R, O'Donnell T, Dorian C, Brierley SM, Blackshaw LA. Ghrelin selectively reduces mechanosensitivity of upper gastrointestinal vagal afferents American Journal of Physiology - Gastrointestinal and Liver Physiology. 292. PMID 17290011 DOI: 10.1152/Ajpgi.00536.2006 |
0.37 |
|
| 2007 |
Hughes PA, Brierley SM, Young RL, Blackshaw LA. Localization and comparative analysis of acid-sensing ion channel (ASIC1, 2, and 3) mRNA expression in mouse colonic sensory neurons within thoracolumbar dorsal root ganglia. The Journal of Comparative Neurology. 500: 863-75. PMID 17177258 DOI: 10.1002/Cne.21204 |
0.385 |
|
| 2006 |
Slattery JA, Page AJ, Dorian CL, Brierley SM, Blackshaw LA. Potentiation of mouse vagal afferent mechanosensitivity by ionotropic and metabotropic glutamate receptors Journal of Physiology. 577: 295-306. PMID 16945965 DOI: 10.1113/Jphysiol.2006.117762 |
0.323 |
|
| 2005 |
Brierley SM, Jones RC, Xu L, Gebhart GF, Blackshaw LA. Activation of splanchnic and pelvic colonic afferents by bradykinin in mice. Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society. 17: 854-62. PMID 16336501 DOI: 10.1111/J.1365-2982.2005.00710.X |
0.364 |
|
| 2005 |
Page AJ, Brierley SM, Martin CM, Price MP, Symonds E, Butler R, Wemmie JA, Blackshaw LA. Different contributions of ASIC channels 1a, 2, and 3 in gastrointestinal mechanosensory function Gut. 54: 1408-1415. PMID 15987792 DOI: 10.1136/Gut.2005.071084 |
0.391 |
|
| 2005 |
Brierley SM, Carter R, Jones W, Xu L, Robinson DR, Hicks GA, Gebhart GF, Blackshaw LA. Differential chemosensory function and receptor expression of splanchnic and pelvic colonic afferents in mice. The Journal of Physiology. 567: 267-81. PMID 15946967 DOI: 10.1113/Jphysiol.2005.089714 |
0.407 |
|
| 2004 |
Page AJ, Brierley SM, Martin CM, Martinez-Salgado C, Wemmie JA, Brennan TJ, Symonds E, Omari T, Lewin GR, Welsh MJ, Blackshaw LA. The ion channel ASIC1 contributes to visceral but not cutaneous mechanoreceptor function. Gastroenterology. 127: 1739-47. PMID 15578512 DOI: 10.1053/J.Gastro.2004.08.061 |
0.355 |
|
| 2004 |
Brierley SM, Jones RC, Gebhart GF, Blackshaw LA. Splanchnic and pelvic mechanosensory afferents signal different qualities of colonic stimuli in mice. Gastroenterology. 127: 166-78. PMID 15236183 DOI: 10.1053/J.Gastro.2004.04.008 |
0.346 |
|
| 2001 |
Brierley SM, Nichols K, Grasby DJ, Waterman SA. Neural mechanisms underlying migrating motor complex formation in mouse isolated colon. British Journal of Pharmacology. 132: 507-17. PMID 11159701 DOI: 10.1038/Sj.Bjp.0703814 |
0.333 |
|
| 2001 |
Brierley SM, Cooper NJ, Lynn PA, Blackshaw LA. Pelvic Vs splanchaic colonic primary afferents Gastroenterology. 120: A178. DOI: 10.1016/S0016-5085(08)80883-9 |
0.301 |
|
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