Year |
Citation |
Score |
2023 |
Rauschenberger V, Piro I, Kasaragod VB, Hörlin V, Eckes AL, Kluck CJ, Schindelin H, Meinck HM, Wickel J, Geis C, Tüzün E, Doppler K, Sommer C, Villmann C. Glycine receptor autoantibody binding to the extracellular domain is independent from receptor glycosylation. Frontiers in Molecular Neuroscience. 16: 1089101. PMID 36860666 DOI: 10.3389/fnmol.2023.1089101 |
0.381 |
|
2021 |
Breitinger U, Weinländer K, Pechmann Y, Langlhofer G, Enz R, Becker CM, Sticht H, Kneussel M, Villmann C, Breitinger HG. A proline-rich motif in the large intracellular loop of the glycine receptor α1 subunit interacts with the Pleckstrin homology domain of collybistin. Journal of Advanced Research. 29: 95-106. PMID 33842008 DOI: 10.1016/j.jare.2020.09.009 |
0.326 |
|
2021 |
Zlotos DP, Abdelmalek CM, Botros LS, Banoub MM, Mandour YM, Breitinger U, El Nady A, Breitinger HG, Sotriffer C, Villmann C, Jensen AA, Holzgrabe U. C-2-Linked Dimeric Strychnine Analogues as Bivalent Ligands Targeting Glycine Receptors. Journal of Natural Products. PMID 33596384 DOI: 10.1021/acs.jnatprod.0c01030 |
0.339 |
|
2020 |
Rauschenberger V, Wardenburg NV, Schaefer N, Ogino K, Hirata H, Lillesaar C, Kluck CJ, Meinck HM, Borrmann M, Weishaupt A, Doppler K, Wickel J, Geis C, Sommer C, Villmann C. GlyR autoantibodies impair receptor function and induce motor dysfunction. Annals of Neurology. PMID 32588476 DOI: 10.1002/Ana.25832 |
0.416 |
|
2020 |
Olander ER, Janzen D, Villmann C, Jensen AA. Comparison of biophysical properties of α1β2 and α3β2 GABAA receptors in whole-cell patch-clamp electrophysiological recordings. Plos One. 15: e0234080. PMID 32479525 DOI: 10.1371/Journal.Pone.0234080 |
0.446 |
|
2020 |
Langlhofer G, Schaefer N, Maric HM, Keramidas A, Zhang Y, Baumann P, Blum R, Breitinger U, Strømgaard K, Schlosser A, Kessels MM, Koch D, Qualmann B, Breitinger HG, Lynch JW, ... Villmann C, et al. A novel glycine receptor variant with startle disease affects syndapin I and glycinergic inhibition. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 32354853 DOI: 10.1523/Jneurosci.2490-19.2020 |
0.534 |
|
2019 |
Zlotos DP, Mohsen AMY, Mandour YM, Marzouk MA, Breitinger U, Villmann C, Breitinger HG, Sotriffer C, Jensen AA, Holzgrabe U. 11-Aminostrychnine and -(Strychnine-11-yl)propionamide: Synthesis, Configuration, and Pharmacological Evaluation at Glycine Receptors. Journal of Natural Products. PMID 31385511 DOI: 10.1021/Acs.Jnatprod.9B00180 |
0.43 |
|
2019 |
Kitzenmaier A, Schaefer N, Kasaragod VB, Polster T, Hantschmann R, Schindelin H, Villmann C. The P429L loss of function mutation of the human glycine transporter 2 associated with hyperekplexia. The European Journal of Neuroscience. PMID 31370103 DOI: 10.1111/Ejn.14533 |
0.336 |
|
2019 |
Kasaragod VB, Hausrat TJ, Schaefer N, Kuhn M, Christensen NR, Tessmer I, Maric HM, Madsen KL, Sotriffer C, Villmann C, Kneussel M, Schindelin H. Elucidating the Molecular Basis for Inhibitory Neurotransmission Regulation by Artemisinins. Neuron. PMID 30704910 DOI: 10.2210/Pdb6Fgd/Pdb |
0.369 |
|
2019 |
Schaefer N, Janzen D, Bakirci E, Hrynevich A, Dalton PD, Villmann C. 3D Electrophysiological Measurements on Cells Embedded within Fiber-Reinforced Matrigel. Advanced Healthcare Materials. e1801226. PMID 30637979 DOI: 10.1002/Adhm.201801226 |
0.331 |
|
2018 |
Schaefer N, Roemer V, Janzen D, Villmann C. Impaired Glycine Receptor Trafficking in Neurological Diseases. Frontiers in Molecular Neuroscience. 11: 291. PMID 30186111 DOI: 10.3389/Fnmol.2018.00291 |
0.434 |
|
2018 |
Schaefer N, Zheng F, van Brederode J, Berger A, Leacock S, Hirata H, Paige CJ, Harvey RJ, Alzheimer C, Villmann C. Functional Consequences of the Postnatal Switch From Neonatal to Mutant Adult Glycine Receptor α1 Subunits in the Mouse Model of Startle Disease. Frontiers in Molecular Neuroscience. 11: 167. PMID 29910711 DOI: 10.3389/Fnmol.2018.00167 |
0.342 |
|
2018 |
Breitinger U, Bahnassawy LM, Janzen D, Roemer V, Becker CM, Villmann C, Breitinger HG. PKA and PKC Modulators Affect Ion Channel Function and Internalization of Recombinant Alpha1 and Alpha1-Beta Glycine Receptors. Frontiers in Molecular Neuroscience. 11: 154. PMID 29867346 DOI: 10.3389/Fnmol.2018.00154 |
0.424 |
|
2017 |
Milanos S, Kuenzel K, Gilbert DF, Janzen D, Sasi M, Buettner A, Frimurer TM, Villmann C. Structural changes at the myrtenol backbone reverse its positive allosteric potential into inhibitory GABAA receptor modulation. Biological Chemistry. PMID 29408795 DOI: 10.1515/Hsz-2017-0262 |
0.426 |
|
2017 |
Janzen D, Schaefer N, Delto C, Schindelin H, Villmann C. The GlyR Extracellular β8-β9 Loop - A Functional Determinant of Agonist Potency. Frontiers in Molecular Neuroscience. 10: 322. PMID 29062270 DOI: 10.3389/Fnmol.2017.00322 |
0.415 |
|
2017 |
Schaefer N, Berger A, van Brederode J, Zheng F, Zhang Y, Leacock S, Littau L, Jablonka S, Malhotra S, Topf M, Winter F, Davydova D, Lynch JW, Paige CJ, Alzheimer C, ... ... Villmann C, et al. Disruption of a structurally important extracellular element in the glycine receptor leads to decreased synaptic integration and signaling resulting in severe startle disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28724750 DOI: 10.1523/Jneurosci.0009-17.2017 |
0.386 |
|
2017 |
Milanos S, Elsharif SA, Janzen D, Buettner A, Villmann C. Metabolic Products of Linalool and Modulation of GABAA Receptors. Frontiers in Chemistry. 5: 46. PMID 28680877 DOI: 10.3389/Fchem.2017.00046 |
0.379 |
|
2017 |
Langlhofer G, Villmann C. The role of charged residues in independent glycine receptor folding domains for intermolecular interactions and ion channel function. Journal of Neurochemistry. PMID 28429370 DOI: 10.1111/Jnc.14049 |
0.488 |
|
2017 |
Sahin S, Eulenburg V, Heinlein A, Villmann C, Pischetsrieder M. Identification of eugenol as the major determinant of GABAA-receptor activation by aqueous Syzygium aromaticum L. (clove buds) extract Journal of Functional Foods. 37: 641-649. DOI: 10.1016/J.Jff.2017.08.033 |
0.323 |
|
2016 |
Mohsen AM, Mandour YM, Sarukhanyan E, Breitinger U, Villmann C, Banoub MM, Breitinger HG, Dandekar T, Holzgrabe U, Sotriffer C, Jensen AA, Zlotos DP. Oxime Ethers of (E)-11-Isonitrosostrychnine as Highly Potent Glycine Receptor Antagonists. Journal of Natural Products. PMID 27966945 DOI: 10.1021/Acs.Jnatprod.6B00479 |
0.415 |
|
2016 |
Sahin S, Eulenburg V, Kreis W, Villmann C, Pischetsrieder M. Three-Step Test System for the Identification of Novel GABAA Receptor Modulating Food Plants. Plant Foods For Human Nutrition (Dordrecht, Netherlands). 71: 355-360. PMID 27392961 DOI: 10.1007/S11130-016-0566-1 |
0.311 |
|
2016 |
Langlhofer G, Villmann C. The Intracellular Loop of the Glycine Receptor: It's not all about the Size. Frontiers in Molecular Neuroscience. 9: 41. PMID 27330534 DOI: 10.3389/Fnmol.2016.00041 |
0.485 |
|
2016 |
van Brederode J, Atak S, Kessler A, Pischetsrieder M, Villmann C, Alzheimer C. The terpenoids Myrtenol and Verbenol act on δ subunit-containing GABAA receptors and enhance tonic inhibition in dentate gyrus granule cells. Neuroscience Letters. PMID 27312536 DOI: 10.1016/J.Neulet.2016.06.027 |
0.367 |
|
2015 |
Atak S, Langlhofer G, Schaefer N, Kessler D, Meiselbach H, Delto C, Schindelin H, Villmann C. Disturbances of Ligand Potency and Enhanced Degradation of the Human Glycine Receptor at Affected Positions G160 and T162 Originally Identified in Patients Suffering from Hyperekplexia. Frontiers in Molecular Neuroscience. 8: 79. PMID 26733802 DOI: 10.3389/Fnmol.2015.00079 |
0.492 |
|
2015 |
Langlhofer G, Janzen D, Meiselbach H, Villmann C. Length of the TM3-4 loop of the glycine receptor modulates receptor desensitization. Neuroscience Letters. 600: 176-81. PMID 26079326 DOI: 10.1016/J.Neulet.2015.06.017 |
0.489 |
|
2015 |
Schaefer N, Kluck CJ, Price KL, Meiselbach H, Vornberger N, Schwarzinger S, Hartmann S, Langlhofer G, Schulz S, Schlegel N, Brockmann K, Lynch B, Becker CM, Lummis SC, Villmann C. Disturbed neuronal ER-Golgi sorting of unassembled glycine receptors suggests altered subcellular processing is a cause of human hyperekplexia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 422-37. PMID 25568133 DOI: 10.1523/Jneurosci.1509-14.2015 |
0.484 |
|
2014 |
Meiselbach H, Vogel N, Langlhofer G, Stangl S, Schleyer B, Bahnassawy L, Sticht H, Breitinger HG, Becker CM, Villmann C. Single expressed glycine receptor domains reconstitute functional ion channels without subunit-specific desensitization behavior. The Journal of Biological Chemistry. 289: 29135-47. PMID 25143388 DOI: 10.1074/Jbc.M114.559138 |
0.532 |
|
2014 |
Kessler A, Sahin-Nadeem H, Lummis SC, Weigel I, Pischetsrieder M, Buettner A, Villmann C. GABA(A) receptor modulation by terpenoids from Sideritis extracts. Molecular Nutrition & Food Research. 58: 851-62. PMID 24273211 DOI: 10.1002/Mnfr.201300420 |
0.362 |
|
2013 |
Schaefer N, Langlhofer G, Kluck CJ, Villmann C. Glycine receptor mouse mutants: model systems for human hyperekplexia. British Journal of Pharmacology. 170: 933-52. PMID 23941355 DOI: 10.1111/Bph.12335 |
0.415 |
|
2012 |
Schaefer N, Vogel N, Villmann C. Glycine receptor mutants of the mouse: what are possible routes of inhibitory compensation? Frontiers in Molecular Neuroscience. 5: 98. PMID 23118727 DOI: 10.3389/Fnmol.2012.00098 |
0.387 |
|
2012 |
Unterer B, Becker CM, Villmann C. The importance of TM3-4 loop subdomains for functional reconstitution of glycine receptors by independent domains. The Journal of Biological Chemistry. 287: 39205-15. PMID 22995908 DOI: 10.1074/Jbc.M112.376053 |
0.575 |
|
2012 |
Becker K, Braune M, Benderska N, Buratti E, Baralle F, Villmann C, Stamm S, Eulenburg V, Becker CM. A retroelement modifies pre-mRNA splicing: the murine Glrb(spa) allele is a splicing signal polymorphism amplified by long interspersed nuclear element insertion. The Journal of Biological Chemistry. 287: 31185-94. PMID 22782896 DOI: 10.1074/Jbc.M112.375691 |
0.332 |
|
2012 |
Kessler A, Villmann C, Sahin-Nadeem H, Pischetsrieder M, Buettner A. GABAA receptor modulation by the volatile fractions of Sideritis species used as ‘Greek’ or ‘Turkish’ mountain tea Flavour and Fragrance Journal. 27: 297-303. DOI: 10.1002/Ffj.3099 |
0.314 |
|
2010 |
Melzer N, Villmann C, Becker K, Harvey K, Harvey RJ, Vogel N, Kluck CJ, Kneussel M, Becker CM. Multifunctional basic motif in the glycine receptor intracellular domain induces subunit-specific sorting. The Journal of Biological Chemistry. 285: 3730-9. PMID 19959465 DOI: 10.1074/Jbc.M109.030460 |
0.494 |
|
2009 |
Villmann C, Oertel J, Melzer N, Becker CM. Recessive hyperekplexia mutations of the glycine receptor alpha1 subunit affect cell surface integration and stability. Journal of Neurochemistry. 111: 837-47. PMID 19732286 DOI: 10.1111/J.1471-4159.2009.06372.X |
0.415 |
|
2009 |
Breitinger HG, Villmann C, Melzer N, Rennert J, Breitinger U, Schwarzinger S, Becker CM. Novel regulatory site within the TM3-4 loop of human recombinant alpha3 glycine receptors determines channel gating and domain structure. The Journal of Biological Chemistry. 284: 28624-33. PMID 19661067 DOI: 10.1074/Jbc.M109.043174 |
0.564 |
|
2009 |
Villmann C, Oertel J, Ma-Högemeier ZL, Hollmann M, Sprengel R, Becker K, Breitinger HG, Becker CM. Functional complementation of Glra1(spd-ot), a glycine receptor subunit mutant, by independently expressed C-terminal domains. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 2440-52. PMID 19244519 DOI: 10.1523/Jneurosci.4400-08.2009 |
0.602 |
|
2008 |
Villmann C, Hoffmann J, Werner M, Kott S, Strutz-Seebohm N, Nilsson T, Hollmann M. Different structural requirements for functional ion pore transplantation suggest different gating mechanisms of NMDA and kainate receptors. Journal of Neurochemistry. 107: 453-65. PMID 18710418 DOI: 10.1111/J.1471-4159.2008.05623.X |
0.764 |
|
2007 |
Villmann C, Becker CM. On the hypes and falls in neuroprotection: targeting the NMDA receptor. The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. 13: 594-615. PMID 17911221 DOI: 10.1177/1073858406296259 |
0.42 |
|
2007 |
Oertel J, Villmann C, Kettenmann H, Kirchhoff F, Becker CM. A novel glycine receptor beta subunit splice variant predicts an unorthodox transmembrane topology. Assembly into heteromeric receptor complexes. The Journal of Biological Chemistry. 282: 2798-807. PMID 17145751 DOI: 10.1074/Jbc.M608941200 |
0.474 |
|
2006 |
Hoffmann J, Villmann C, Werner M, Hollmann M. Investigation via ion pore transplantation of the putative relationship between glutamate receptors and K+ channels. Molecular and Cellular Neurosciences. 33: 358-70. PMID 17011207 DOI: 10.1016/J.Mcn.2006.08.004 |
0.726 |
|
2005 |
Paarmann I, Frermann D, Keller BU, Villmann C, Breitinger HG, Hollmann M. Kinetics and subunit composition of NMDA receptors in respiratory-related neurons. Journal of Neurochemistry. 93: 812-24. PMID 15857385 DOI: 10.1111/J.1471-4159.2005.03027.X |
0.568 |
|
2002 |
Strutz N, Villmann C, Breitinger HG, Werner M, Wenthold RJ, Kizelsztein P, Teichberg VI, Hollmann M. Kainate-binding proteins are rendered functional ion channels upon transplantation of two short pore-flanking domains from a kainate receptor. The Journal of Biological Chemistry. 277: 48035-42. PMID 12370171 DOI: 10.1074/Jbc.M209647200 |
0.741 |
|
2002 |
Breitinger HG, Villmann C, Rennert J, Ballhausen D, Becker CM. Hydroxylated residues influence desensitization behaviour of recombinant alpha3 glycine receptor channels. Journal of Neurochemistry. 83: 30-6. PMID 12358726 DOI: 10.1046/J.1471-4159.2002.01109.X |
0.555 |
|
2001 |
Breitinger HG, Villmann C, Becker K, Becker CM. Opposing effects of molecular volume and charge at the hyperekplexia site alpha 1(P250) govern glycine receptor activation and desensitization. The Journal of Biological Chemistry. 276: 29657-63. PMID 11395484 DOI: 10.1074/Jbc.M100446200 |
0.455 |
|
2001 |
Strutz N, Villmann C, Thalhammer A, Kizelsztein P, Eisenstein M, Teichberg VI, Hollmann M. Identification of domains and amino acids involved in GLuR7 ion channel function. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 401-11. PMID 11160421 DOI: 10.1523/Jneurosci.21-02-00401.2001 |
0.748 |
|
2001 |
Strutz N, Villmann C, Thalhammer A, Kizelsztein P, Eisenstein M, Teichberg VI, Hollmann M. Identification of Domains and Amino Acids Involved in GluR7 Ion Channel Function The Journal of Neuroscience. 21: 401-411. DOI: 10.1523/JNEUROSCI.21-02-00401.2001 |
0.718 |
|
2000 |
Butler MH, Hayashi A, Ohkoshi N, Villmann C, Becker CM, Feng G, De Camilli P, Solimena M. Autoimmunity to gephyrin in Stiff-Man syndrome. Neuron. 26: 307-12. PMID 10839351 DOI: 10.1016/S0896-6273(00)81165-4 |
0.322 |
|
1999 |
Villmann C, Strutz N, Morth T, Hollmann M. Investigation by ion channel domain transplantation of rat glutamate receptor subunits, orphan receptors and a putative NMDA receptor subunit. The European Journal of Neuroscience. 11: 1765-78. PMID 10215929 DOI: 10.1046/J.1460-9568.1999.00594.X |
0.703 |
|
1997 |
Everts I, Villmann C, Hollmann M. N-Glycosylation is not a prerequisite for glutamate receptor function but Is essential for lectin modulation. Molecular Pharmacology. 52: 861-73. PMID 9351977 DOI: 10.1124/Mol.52.5.861 |
0.658 |
|
1997 |
Villmann C, Bull L, Hollmann M. Kainate binding proteins possess functional ion channel domains. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 7634-43. PMID 9315885 DOI: 10.1523/Jneurosci.17-20-07634.1997 |
0.68 |
|
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