| Year |
Citation |
Score |
| 2018 |
Breitinger U, Bahnassawy LM, Janzen D, Roemer V, Becker CM, Villmann C, Breitinger HG. PKA and PKC Modulators Affect Ion Channel Function and Internalization of Recombinant Alpha1 and Alpha1-Beta Glycine Receptors. Frontiers in Molecular Neuroscience. 11: 154. PMID 29867346 DOI: 10.3389/Fnmol.2018.00154 |
0.372 |
|
| 2016 |
Dlugaiczyk J, Hecker D, Neubert C, Buerbank S, Campanelli D, Becker CM, Betz H, Knipper M, Rüttiger L, Schick B. Loss of glycine receptors containing the α3 subunit compromises auditory nerve activity, but not outer hair cell function. Hearing Research. PMID 27208792 DOI: 10.1016/j.heares.2016.05.004 |
0.309 |
|
| 2015 |
Schaefer N, Kluck CJ, Price KL, Meiselbach H, Vornberger N, Schwarzinger S, Hartmann S, Langlhofer G, Schulz S, Schlegel N, Brockmann K, Lynch B, Becker CM, Lummis SC, Villmann C. Disturbed neuronal ER-Golgi sorting of unassembled glycine receptors suggests altered subcellular processing is a cause of human hyperekplexia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 422-37. PMID 25568133 DOI: 10.1523/Jneurosci.1509-14.2015 |
0.401 |
|
| 2014 |
Meiselbach H, Vogel N, Langlhofer G, Stangl S, Schleyer B, Bahnassawy L, Sticht H, Breitinger HG, Becker CM, Villmann C. Single expressed glycine receptor domains reconstitute functional ion channels without subunit-specific desensitization behavior. The Journal of Biological Chemistry. 289: 29135-47. PMID 25143388 DOI: 10.1074/Jbc.M114.559138 |
0.391 |
|
| 2012 |
Unterer B, Becker CM, Villmann C. The importance of TM3-4 loop subdomains for functional reconstitution of glycine receptors by independent domains. The Journal of Biological Chemistry. 287: 39205-15. PMID 22995908 DOI: 10.1074/Jbc.M112.376053 |
0.407 |
|
| 2012 |
Becker K, Braune M, Benderska N, Buratti E, Baralle F, Villmann C, Stamm S, Eulenburg V, Becker CM. A retroelement modifies pre-mRNA splicing: the murine Glrb(spa) allele is a splicing signal polymorphism amplified by long interspersed nuclear element insertion. The Journal of Biological Chemistry. 287: 31185-94. PMID 22782896 DOI: 10.1074/Jbc.M112.375691 |
0.332 |
|
| 2011 |
Buerbank S, Becker K, Becker CM, Brandt N, Engel J, Knipper M, Schick B, Dlugaiczyk J. Developmental regulation of glycine receptors at efferent synapses of the murine cochlea. Histochemistry and Cell Biology. 136: 387-98. PMID 21850450 DOI: 10.1007/s00418-011-0855-6 |
0.335 |
|
| 2011 |
Seebahn A, Dinkel H, Mohrlüder J, Hartmann R, Vogel N, Becker CM, Sticht H, Enz R. Structural characterization of intracellular C-terminal domains of group III metabotropic glutamate receptors. Febs Letters. 585: 511-6. PMID 21219903 DOI: 10.1016/j.febslet.2010.12.042 |
0.345 |
|
| 2010 |
Melzer N, Villmann C, Becker K, Harvey K, Harvey RJ, Vogel N, Kluck CJ, Kneussel M, Becker CM. Multifunctional basic motif in the glycine receptor intracellular domain induces subunit-specific sorting. The Journal of Biological Chemistry. 285: 3730-9. PMID 19959465 DOI: 10.1074/Jbc.M109.030460 |
0.379 |
|
| 2009 |
Vogel N, Kluck CJ, Melzer N, Schwarzinger S, Breitinger U, Seeber S, Becker CM. Mapping of disulfide bonds within the amino-terminal extracellular domain of the inhibitory glycine receptor. The Journal of Biological Chemistry. 284: 36128-36. PMID 19861413 DOI: 10.1074/jbc.M109.043448 |
0.365 |
|
| 2009 |
Villmann C, Oertel J, Melzer N, Becker CM. Recessive hyperekplexia mutations of the glycine receptor alpha1 subunit affect cell surface integration and stability. Journal of Neurochemistry. 111: 837-47. PMID 19732286 DOI: 10.1111/J.1471-4159.2009.06372.X |
0.376 |
|
| 2009 |
Breitinger HG, Villmann C, Melzer N, Rennert J, Breitinger U, Schwarzinger S, Becker CM. Novel regulatory site within the TM3-4 loop of human recombinant alpha3 glycine receptors determines channel gating and domain structure. The Journal of Biological Chemistry. 284: 28624-33. PMID 19661067 DOI: 10.1074/Jbc.M109.043174 |
0.397 |
|
| 2009 |
Villmann C, Oertel J, Ma-Högemeier ZL, Hollmann M, Sprengel R, Becker K, Breitinger HG, Becker CM. Functional complementation of Glra1(spd-ot), a glycine receptor subunit mutant, by independently expressed C-terminal domains. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 2440-52. PMID 19244519 DOI: 10.1523/Jneurosci.4400-08.2009 |
0.377 |
|
| 2008 |
Hutchinson M, Waters P, McHugh J, Gorman G, O'Riordan S, Connolly S, Hager H, Yu P, Becker CM, Vincent A. Progressive encephalomyelitis, rigidity, and myoclonus: a novel glycine receptor antibody. Neurology. 71: 1291-2. PMID 18852446 DOI: 10.1212/01.wnl.0000327606.50322.f0 |
0.397 |
|
| 2008 |
Dlugaiczyk J, Singer W, Schick B, Iro H, Becker K, Becker CM, Zimmermann U, Rohbock K, Knipper M. Expression of glycine receptors and gephyrin in the rat cochlea. Histochemistry and Cell Biology. 129: 513-23. PMID 18231803 DOI: 10.1007/s00418-008-0387-x |
0.365 |
|
| 2008 |
Becker K, Breitinger HG, Humeny A, Meinck HM, Dietz B, Aksu F, Becker CM. The novel hyperekplexia allele GLRA1(S267N) affects the ethanol site of the glycine receptor. European Journal of Human Genetics : Ejhg. 16: 223-8. PMID 18043720 DOI: 10.1038/sj.ejhg.5201958 |
0.39 |
|
| 2007 |
Villmann C, Becker CM. On the hypes and falls in neuroprotection: targeting the NMDA receptor. The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. 13: 594-615. PMID 17911221 DOI: 10.1177/1073858406296259 |
0.342 |
|
| 2007 |
Meltretter J, Seeber S, Humeny A, Becker CM, Pischetsrieder M. Site-specific formation of Maillard, oxidation, and condensation products from whey proteins during reaction with lactose. Journal of Agricultural and Food Chemistry. 55: 6096-103. PMID 17590008 DOI: 10.1021/jf0705567 |
0.306 |
|
| 2007 |
Oertel J, Villmann C, Kettenmann H, Kirchhoff F, Becker CM. A novel glycine receptor beta subunit splice variant predicts an unorthodox transmembrane topology. Assembly into heteromeric receptor complexes. The Journal of Biological Chemistry. 282: 2798-807. PMID 17145751 DOI: 10.1074/Jbc.M608941200 |
0.419 |
|
| 2007 |
Ulrich M, Seeber S, Becker CM, Enz R. Tax1-binding protein 1 is expressed in the retina and interacts with the GABA(C) receptor rho1 subunit. The Biochemical Journal. 401: 429-36. PMID 16999686 DOI: 10.1042/BJ20061036 |
0.413 |
|
| 2007 |
Breitinger H, Becker K, Rennert J, Vohwinkel C, Becker C. Assembly of ligand-gated ion channel receptors – how individual subunits contribute to receptor function Bmc Neuroscience. 8. DOI: 10.1186/1471-2202-8-S1-P37 |
0.371 |
|
| 2006 |
Becker K, Hohoff C, Schmitt B, Christen HJ, Neubauer BA, Sandrieser T, Becker CM. Identification of the microdeletion breakpoint in a GLRA1null allele of Turkish hyperekplexia patients. Human Mutation. 27: 1061-2. PMID 16941485 DOI: 10.1002/humu.9455 |
0.321 |
|
| 2006 |
Eulenburg V, Becker K, Gomeza J, Schmitt B, Becker CM, Betz H. Mutations within the human GLYT2 (SLC6A5) gene associated with hyperekplexia. Biochemical and Biophysical Research Communications. 348: 400-5. PMID 16884688 DOI: 10.1016/j.bbrc.2006.07.080 |
0.324 |
|
| 2004 |
Breitinger HG, Lanig H, Vohwinkel C, Grewer C, Breitinger U, Clark T, Becker CM. Molecular dynamics simulation links conformation of a pore-flanking region to hyperekplexia-related dysfunction of the inhibitory glycine receptor. Chemistry & Biology. 11: 1339-50. PMID 15489161 DOI: 10.1016/J.Chembiol.2004.07.008 |
0.387 |
|
| 2004 |
Seeber S, Humeny A, Herkert M, Rau T, Eschenhagen T, Becker CM. Formation of molecular complexes by N-methyl-D-aspartate receptor subunit NR2B and ryanodine receptor 2 in neonatal rat myocard. The Journal of Biological Chemistry. 279: 21062-8. PMID 15010472 DOI: 10.1074/jbc.M313009200 |
0.374 |
|
| 2004 |
Brill J, Klocke R, Paul D, Boison D, Gouder N, Klugbauer N, Hofmann F, Becker CM, Becker K. entla, a novel epileptic and ataxic Cacna2d2 mutant of the mouse. The Journal of Biological Chemistry. 279: 7322-30. PMID 14660671 DOI: 10.1074/jbc.M308778200 |
0.547 |
|
| 2004 |
Breitinger U, Breitinger HG, Bauer F, Fahmy K, Glockenhammer D, Becker CM. Conserved high affinity ligand binding and membrane association in the native and refolded extracellular domain of the human glycine receptor alpha1-subunit. The Journal of Biological Chemistry. 279: 1627-36. PMID 14593111 DOI: 10.1074/jbc.M303811200 |
0.357 |
|
| 2002 |
Breitinger HG, Becker CM. The inhibitory glycine receptor-simple views of a complicated channel. Chembiochem : a European Journal of Chemical Biology. 3: 1042-52. PMID 12404628 DOI: 10.1002/1439-7633(20021104)3:11<1042::AID-CBIC1042>3.0.CO;2-7 |
0.419 |
|
| 2002 |
Breitinger HG, Becker CM. Statistical coassembly of glycine receptor alpha1 wildtype and the hyperekplexia mutant alpha1(P250T) in HEK 293 cells: impaired channel function is not dominant in the recombinant system. Neuroscience Letters. 331: 21-4. PMID 12359314 DOI: 10.1016/S0304-3940(02)00773-5 |
0.394 |
|
| 2002 |
Breitinger HG, Villmann C, Rennert J, Ballhausen D, Becker CM. Hydroxylated residues influence desensitization behaviour of recombinant alpha3 glycine receptor channels. Journal of Neurochemistry. 83: 30-6. PMID 12358726 DOI: 10.1046/J.1471-4159.2002.01109.X |
0.419 |
|
| 2002 |
Humeny A, Bonk T, Becker K, Jafari-Boroujerdi M, Stephani U, Reuter K, Becker CM. A novel recessive hyperekplexia allele GLRA1 (S231R): genotyping by MALDI-TOF mass spectrometry and functional characterisation as a determinant of cellular glycine receptor trafficking. European Journal of Human Genetics : Ejhg. 10: 188-96. PMID 11973623 DOI: 10.1038/sj.ejhg.5200779 |
0.403 |
|
| 2001 |
Sobetzko D, Sander T, Becker CM. Genetic variation of the human glycine receptor subunit genes GLRA3 and GLRB and susceptibility to idiopathic generalized epilepsies. American Journal of Medical Genetics. 105: 534-8. PMID 11496371 DOI: 10.1002/ajmg.1488 |
0.347 |
|
| 2001 |
Breitinger HG, Villmann C, Becker K, Becker CM. Opposing effects of molecular volume and charge at the hyperekplexia site alpha 1(P250) govern glycine receptor activation and desensitization. The Journal of Biological Chemistry. 276: 29657-63. PMID 11395484 DOI: 10.1074/Jbc.M100446200 |
0.377 |
|
| 2001 |
Plappert CF, Pilz PK, Becker K, Becker CM, Schnitzler HU. Increased sensitization of acoustic startle response in spasmodic mice with a mutation of the glycine receptor alpha1-subunit gene. Behavioural Brain Research. 121: 57-67. PMID 11275284 DOI: 10.1016/S0166-4328(00)00385-5 |
0.31 |
|
| 2000 |
Seeber S, Becker K, Rau T, Eschenhagen T, Becker CM, Herkert M. Transient expression of NMDA receptor subunit NR2B in the developing rat heart. Journal of Neurochemistry. 75: 2472-7. PMID 11080199 DOI: 10.1046/j.1471-4159.2000.0752472.x |
0.379 |
|
| 1999 |
Saul B, Kuner T, Sobetzko D, Brune W, Hanefeld F, Meinck HM, Becker CM. Novel GLRA1 missense mutation (P250T) in dominant hyperekplexia defines an intracellular determinant of glycine receptor channel gating. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 869-77. PMID 9920650 DOI: 10.1523/Jneurosci.19-03-00869.1999 |
0.387 |
|
| 1999 |
Charton JP, Herkert M, Becker CM, Schröder H. Cellular and subcellular localization of the 2B-subunit of the NMDA receptor in the adult rat telencephalon. Brain Research. 816: 609-17. PMID 9878886 DOI: 10.1016/S0006-8993(98)01243-8 |
0.355 |
|
| 1998 |
Herkert M, Röttger S, Becker CM. The NMDA receptor subunit NR2B of neonatal rat brain: complex formation and enrichment in axonal growth cones. The European Journal of Neuroscience. 10: 1553-62. PMID 9751128 DOI: 10.1046/J.1460-9568.1998.00164.X |
0.372 |
|
| 1998 |
Wässle H, Koulen P, Brandstätter JH, Fletcher EL, Becker CM. Glycine and GABA receptors in the mammalian retina. Vision Research. 38: 1411-30. PMID 9667008 DOI: 10.1016/S0042-6989(97)00300-3 |
0.367 |
|
| 1997 |
Kling C, Koch M, Saul B, Becker CM. The frameshift mutation oscillator (Glra1(spd-ot)) produces a complete loss of glycine receptor alpha1-polypeptide in mouse central nervous system. Neuroscience. 78: 411-7. PMID 9145798 DOI: 10.1016/S0306-4522(96)00567-2 |
0.319 |
|
| 1997 |
Becker C. Natural Glycine Receptor Mutants In Human And Murine Disease Biochemical Society Transactions. 25. DOI: 10.1042/Bst025535Sc |
0.342 |
|
| 1996 |
Koch M, Kling C, Becker CM. Increased startle responses in mice carrying mutations of glycine receptor subunit genes. Neuroreport. 7: 806-8. PMID 8733750 DOI: 10.1097/00001756-199602290-00030 |
0.382 |
|
| 1996 |
Kirchhoff F, Mülhardt C, Pastor A, Becker CM, Kettenmann H. Expression of glycine receptor subunits in glial cells of the rat spinal cord. Journal of Neurochemistry. 66: 1383-90. PMID 8627289 DOI: 10.1046/J.1471-4159.1996.66041383.X |
0.367 |
|
| 1995 |
Becker CM. Review : Glycine Receptors: Molecular Heterogeneity and Implications for Disease The Neuroscientist. 1: 130-141. DOI: 10.1177/107385849500100304 |
0.379 |
|
| 1994 |
Saul B, Schmieden V, Kling C, Mülhardt C, Gass P, Kuhse J, Becker CM. Point mutation of glycine receptor alpha 1 subunit in the spasmodic mouse affects agonist responses. Febs Letters. 350: 71-6. PMID 8062927 DOI: 10.1016/0014-5793(94)00736-5 |
0.433 |
|
| 1994 |
Becker CM, Kling C, Mülhardt C, Saul B, Herkert M, Kuhse J. The inhibitory glycine receptor. A candidate protein of signal transduction in neuroendocrine tissue. Annals of the New York Academy of Sciences. 733: 155-62. PMID 7978863 DOI: 10.1111/j.1749-6632.1994.tb17265.x |
0.323 |
|
| 1994 |
Mülhardt C, Fischer M, Gass P, Simon-Chazottes D, Guénet JL, Kuhse J, Betz H, Becker CM. The spastic mouse: aberrant splicing of glycine receptor beta subunit mRNA caused by intronic insertion of L1 element. Neuron. 13: 1003-15. PMID 7946325 DOI: 10.1016/0896-6273(94)90265-8 |
0.34 |
|
| 1993 |
Becker CM, Betz H, Schröder H. Expression of inhibitory glycine receptors in postnatal rat cerebral cortex. Brain Research. 606: 220-6. PMID 8387859 DOI: 10.1016/0006-8993(93)90988-Y |
0.335 |
|
| 1993 |
Gass P, Muelhardt C, Sommer C, Becker CM, Kiessling M. NMDA and glycine receptor mRNA expression following transient global ischemia in the gerbil brain. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 13: 337-41. PMID 8382215 DOI: 10.1038/jcbfm.1993.42 |
0.325 |
|
| 1992 |
Becker CM, Schmieden V, Tarroni P, Strasser U, Betz H. Isoform-selective deficit of glycine receptors in the mouse mutant spastic. Neuron. 8: 283-9. PMID 1371219 DOI: 10.1016/0896-6273(92)90295-O |
0.378 |
|
| 1991 |
Becker CM, Seitanidou T, Triller A. Conservation of antigenic epitopes of the inhibitory glycine receptor in rodent and goldfish CNS. Brain Research. Molecular Brain Research. 11: 327-33. PMID 1721995 DOI: 10.1016/0169-328X(91)90042-V |
0.415 |
|
| 1991 |
Naas E, Zilles K, Gnahn H, Betz H, Becker CM, Schröder H. Glycine receptor immunoreactivity in rat and human cerebral cortex. Brain Research. 561: 139-46. PMID 1665751 DOI: 10.1016/0006-8993(91)90758-N |
0.362 |
|
| 1990 |
Langosch D, Becker CM, Betz H. The inhibitory glycine receptor: a ligand-gated chloride channel of the central nervous system. European Journal of Biochemistry / Febs. 194: 1-8. PMID 2174770 DOI: 10.1111/j.1432-1033.1990.tb19419.x |
0.387 |
|
| 1990 |
Becker CM. Disorders of the inhibitory glycine receptor: the spastic mouse. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 4: 2767-74. PMID 2165011 DOI: 10.1096/Fasebj.4.10.2165011 |
0.388 |
|
| 1989 |
Hoch W, Betz H, Becker CM. Primary cultures of mouse spinal cord express the neonatal isoform of the inhibitory glycine receptor. Neuron. 3: 339-48. PMID 2561971 DOI: 10.1016/0896-6273(89)90258-4 |
0.395 |
|
| 1989 |
Sontheimer H, Becker CM, Pritchett DB, Schofield PR, Grenningloh G, Kettenmann H, Betz H, Seeburg PH. Functional chloride channels by mammalian cell expression of rat glycine receptor subunit. Neuron. 2: 1491-7. PMID 2483325 DOI: 10.1016/0896-6273(89)90195-5 |
0.394 |
|
| 1989 |
Becker CM, Hoch W, Betz H. Sensitive immunoassay shows selective association of peripheral and integral membrane proteins of the inhibitory glycine receptor complex. Journal of Neurochemistry. 53: 124-31. PMID 2470857 DOI: 10.1111/J.1471-4159.1989.Tb07303.X |
0.417 |
|
| 1988 |
Betz H, Becker CM. The mammalian glycine receptor: biology and structure of a neuronal chloride channel protein. Neurochemistry International. 13: 137-46. PMID 20501281 DOI: 10.1016/0197-0186(88)90048-4 |
0.428 |
|
| 1987 |
Rienitz A, Becker CM, Betz H, Schmitt B. The chloride channel blocking agent, t-butyl bicyclophosphorothionate, binds to the gamma-aminobutyric acid-benzodiazepine, but not to the glycine receptor in rodents. Neuroscience Letters. 76: 91-5. PMID 3035434 DOI: 10.1016/0304-3940(87)90198-4 |
0.376 |
|
| 1987 |
Betz H, Schmitt B, Becker CM, Grenningloh G, Rienitz A, Hermans-Borgmeyer I, Zopf D, Schloss P, Sawruk E, Gundelfinger E. Structure and biology of central nervous system neurotransmitter receptors. Biochemical Society Transactions. 15: 107-8. PMID 3030836 DOI: 10.1042/Bst0150107 |
0.344 |
|
| 1986 |
Becker CM, Hermans-Borgmeyer I, Schmitt B, Betz H. The glycine receptor deficiency of the mutant mouse spastic: evidence for normal glycine receptor structure and localization. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 6: 1358-64. PMID 3012014 DOI: 10.1523/Jneurosci.06-05-01358.1986 |
0.408 |
|
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