| Year |
Citation |
Score |
| 2022 |
Han W, Yuan H, Allen JP, Kim S, Shaulsky GH, Perszyk RE, Traynelis SF, Myers SJ. . The Journal of Pharmacology and Experimental Therapeutics. PMID 35110392 DOI: 10.1124/jpet.121.001000 |
0.789 |
|
| 2021 |
Hansen KB, Wollmuth LP, Bowie D, Furukawa H, Menniti FS, Sobolevsky AI, Swanson GT, Swanger SA, Greger IH, Nakagawa T, McBain CJ, Jayaraman V, Low CM, Dell'Acqua ML, Diamond JS, ... ... Perszyk RE, et al. Structure, Function, and Pharmacology of Glutamate Receptor Ion Channels. Pharmacological Reviews. 73: 298-487. PMID 34753794 DOI: 10.1124/pharmrev.120.000131 |
0.778 |
|
| 2021 |
Perszyk RE, Kristensen AS, Lyuboslavsky P, Traynelis SF. Three-dimensional missense tolerance ratio analysis. Genome Research. PMID 34301626 DOI: 10.1101/gr.275528.121 |
0.695 |
|
| 2021 |
Perszyk RE, Yip MC, McConnell OL, Wang ET, Jenkins A, Traynelis SF, Forest CR. Automated intracellular pharmacological electrophysiology for ligand-gated ionotropic receptor and pharmacology screening. Molecular Pharmacology. PMID 33958481 DOI: 10.1124/molpharm.120.000195 |
0.68 |
|
| 2021 |
Perszyk RE, Zheng Z, Banke TG, Zhang J, Xie L, McDaniel MJ, Katzman BM, Pelly SC, Yuan H, Liotta DC, Traynelis SF. . Molecular Pharmacology. PMID 33688039 DOI: 10.1124/molpharm.120.000218 |
0.816 |
|
| 2020 |
Strong KL, Epplin MP, Ogden KK, Burger PB, Kaiser TM, Wilding TJ, Kusumoto H, Camp CR, Shaulsky G, Bhattacharya S, Perszyk RE, Menaldino DS, McDaniel MJ, Zhang J, Le P, et al. Distinct GluN1 and GluN2 Structural Determinants for Subunit-Selective Positive Allosteric Modulation of -Methyl-d-aspartate Receptors. Acs Chemical Neuroscience. PMID 33326224 DOI: 10.1021/acschemneuro.0c00561 |
0.727 |
|
| 2020 |
Perszyk RE, Myers SJ, Yuan H, Gibb AJ, Furukawa H, Sobolevsky AI, Traynelis SF. Hodgkin-huxley-katz prize lecture: genetic and pharmacological control of glutamate receptor channel through a highly conserved gating motif. The Journal of Physiology. PMID 32468591 DOI: 10.1113/Jp278086 |
0.789 |
|
| 2020 |
Perszyk RE, Swanger SA, Shelley C, Khatri A, Fernandez-Cuervo G, Epplin MP, Zhang J, Le P, Bülow P, Garnier-Amblard E, Gangireddy PKR, Bassell GJ, Yuan H, Menaldino DS, Liotta DC, et al. Biased modulators of NMDA receptors control channel opening and ion selectivity. Nature Chemical Biology. PMID 31959964 DOI: 10.1038/S41589-019-0449-5 |
0.773 |
|
| 2018 |
Hansen KB, Yi F, Perszyk RE, Furukawa H, Wollmuth LP, Gibb AJ, Traynelis SF. Structure, function, and allosteric modulation of NMDA receptors. The Journal of General Physiology. PMID 30037851 DOI: 10.1085/Jgp.201812032 |
0.798 |
|
| 2018 |
Perszyk R, Katzman BM, Kusumoto H, Kell SA, Epplin MP, Tahirovic YA, Moore RL, Menaldino D, Burger P, Liotta DC, Traynelis SF. An NMDAR positive and negative allosteric modulator series share a binding site and are interconverted by methyl groups. Elife. 7. PMID 29792594 DOI: 10.7554/Elife.34711 |
0.698 |
|
| 2018 |
Perszyk R, Katzman BM, Kusumoto H, Kell SA, Epplin MP, Tahirovic YA, Moore RL, Menaldino D, Burger P, Liotta DC, Traynelis SF. Author response: An NMDAR positive and negative allosteric modulator series share a binding site and are interconverted by methyl groups Elife. DOI: 10.7554/Elife.34711.058 |
0.457 |
|
| 2017 |
Hansen KB, Yi F, Perszyk RE, Menniti FS, Traynelis SF. NMDA Receptors in the Central Nervous System. Methods in Molecular Biology (Clifton, N.J.). 1677: 1-80. PMID 28986865 DOI: 10.1007/978-1-4939-7321-7_1 |
0.796 |
|
| 2017 |
Perszyk RE, Ogden KK, Strong KL, Liotta DC, Traynelis SF. Channel Open Probability Controls Allosteric Modulation of Potency and Efficacy Biophysical Journal. 112: 420a-421a. DOI: 10.1016/J.Bpj.2016.11.2249 |
0.728 |
|
| 2016 |
Perszyk RE, DiRaddo JO, Strong KL, Low CM, Ogden KK, Khatri A, Vargish GA, Pelkey KA, Tricoire L, Liotta DC, Smith Y, McBain CJ, Traynelis SF. GluN2D-containing NMDA receptors mediate synaptic transmission in hippocampal interneurons and regulate interneuron activity. Molecular Pharmacology. PMID 27625038 DOI: 10.1124/Mol.116.105130 |
0.751 |
|
| 2015 |
Katzman BM, Perszyk RE, Yuan H, Tahirovic YA, Sotimehin AE, Traynelis SF, Liotta DC. A novel class of negative allosteric modulators of NMDA receptor function. Bioorganic & Medicinal Chemistry Letters. 25: 5583-8. PMID 26525866 DOI: 10.1016/J.Bmcl.2015.10.046 |
0.797 |
|
| 2013 |
Hansen KB, Tajima N, Risgaard R, Perszyk RE, Jørgensen L, Vance KM, Ogden KK, Clausen RP, Furukawa H, Traynelis SF. Structural determinants of agonist efficacy at the glutamate binding site of N-methyl-D-aspartate receptors. Molecular Pharmacology. 84: 114-27. PMID 23625947 DOI: 10.1124/Mol.113.085803 |
0.811 |
|
| 2011 |
Perszyk RE, Wiliams CA, Jenkins A. A conserved Asparagine Between Loops A and E of Anion Ligand-Gated Channels is Critical for Gaba(A) Receptor Function Biophysical Journal. 100: 271a. DOI: 10.1016/j.bpj.2010.12.1690 |
0.557 |
|
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