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Solange P. Brown, M.D. Ph.D. - Publications

Affiliations: 
Johns Hopkins University, Baltimore, MD 
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36 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Frandolig JE, Matney CJ, Lee K, Kim J, Chevée M, Kim SJ, Bickert AA, Brown SP. The Synaptic Organization of Layer 6 Circuits Reveals Inhibition as a Major Output of a Neocortical Sublamina. Cell Reports. 28: 3131-3143.e5. PMID 31533036 DOI: 10.1016/j.celrep.2019.08.048  1
2018 Chevée M, Brown SP. The development of local circuits in the neocortex: recent lessons from the mouse visual cortex. Current Opinion in Neurobiology. 53: 103-109. PMID 30053693 DOI: 10.1016/j.conb.2018.06.009  0.96
2018 Minamisawa G, Kwon SE, Chevée M, Brown SP, O'Connor DH. A Non-canonical Feedback Circuit for Rapid Interactions between Somatosensory Cortices. Cell Reports. 23: 2718-2731.e6. PMID 29847801 DOI: 10.1016/j.celrep.2018.04.115  0.96
2018 Chevée M, Robertson JJ, Cannon GH, Brown SP, Goff LA. Variation in Activity State, Axonal Projection, and Position Define the Transcriptional Identity of Individual Neocortical Projection Neurons. Cell Reports. 22: 441-455. PMID 29320739 DOI: 10.1016/j.celrep.2017.12.046  0.96
2017 Liu K, Kim J, Kim DW, Stephanie Zhang Y, Bao H, Denaxa M, Lim SA, Kim E, Liu C, Wickersham IR, Pachnis V, Hattar S, Song J, Brown SP, Blackshaw S. Corrigendum: Lhx6-positive GABA-releasing neurons of the zona incerta promote sleep. Nature. PMID 28953871 DOI: 10.1038/nature24274  1
2017 Liu K, Kim J, Kim DW, Zhang YS, Bao H, Denaxa M, Lim SA, Kim E, Liu C, Wickersham IR, Pachinis V, Hattar S, Song J, Brown SP, Blackshaw S. Lhx6-positive GABA-releasing neurons of the zona incerta promote sleep. Nature. PMID 28847002 DOI: 10.1038/nature23663  1
2017 Kim J, Hughes EG, Shetty AS, Arlotta P, Goff LA, Bergles DE, Brown SP. Changes in the excitability of neocortical neurons in a mouse model of amyotrophic lateral sclerosis are not specific to corticospinal neurons and are modulated by advancing disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28821643 DOI: 10.1523/JNEUROSCI.0811-17.2017  1
2017 Langseth AJ, Kim J, Ugolino JE, Shah Y, Hwang HY, Wang J, Bergles DE, Brown SP. Cell-type specific differences in promoter activity of the ALS-linked C9orf72 mouse ortholog. Scientific Reports. 7: 5685. PMID 28720882 DOI: 10.1038/s41598-017-05864-2  1
2016 Zhang Y, Nikolovski N, Sorieul M, Vellosillo T, McFarlane HE, Dupree R, Kesten C, Schneider R, Driemeier C, Lathe R, Lampugnani E, Yu X, Ivakov A, Doblin MS, Mortimer JC, ... Brown SP, et al. Golgi-localized STELLO proteins regulate the assembly and trafficking of cellulose synthase complexes in Arabidopsis. Nature Communications. 7: 11656. PMID 27277162 DOI: 10.1038/ncomms11656  0.32
2016 Kim J, Matney CJ, Roth RH, Brown SP. Synaptic Organization of the Neuronal Circuits of the Claustrum. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 773-84. PMID 26791208 DOI: 10.1523/JNEUROSCI.3643-15.2016  1
2015 Peters OM, Cabrera GT, Tran H, Gendron TF, McKeon JE, Metterville J, Weiss A, Wightman N, Salameh J, Kim J, Sun H, Boylan KB, Dickson D, Kennedy Z, Lin Z, ... ... Brown SP, et al. Human C9ORF72 Hexanucleotide Expansion Reproduces RNA Foci and Dipeptide Repeat Proteins but Not Neurodegeneration in BAC Transgenic Mice. Neuron. 88: 902-909. PMID 26637797 DOI: 10.1016/j.neuron.2015.11.018  1
2015 Brown SP, Smith AB. Peptide/protein stapling and unstapling: introduction of s-tetrazine, photochemical release, and regeneration of the peptide/protein. Journal of the American Chemical Society. 137: 4034-7. PMID 25793939 DOI: 10.1021/ja512880g  0.32
2015 Dupree R, Simmons TJ, Mortimer JC, Patel D, Iuga D, Brown SP, Dupree P. Probing the molecular architecture of Arabidopsis thaliana secondary cell walls using two- and three-dimensional (13)C solid state nuclear magnetic resonance spectroscopy. Biochemistry. 54: 2335-45. PMID 25739924 DOI: 10.1021/bi501552k  0.32
2014 Kim J, Matney CJ, Blankenship A, Hestrin S, Brown SP. Layer 6 corticothalamic neurons activate a cortical output layer, layer 5a. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 9656-64. PMID 25031405 DOI: 10.1523/JNEUROSCI.1325-14.2014  1
2014 Liu JJ, Wang Y, Ma Z, Schmitt M, Zhu L, Brown SP, Dransfield PJ, Sun Y, Sharma R, Guo Q, Zhuang R, Zhang J, Luo J, Tonn GR, Wong S, et al. Optimization of GPR40 Agonists for Type 2 Diabetes. Acs Medicinal Chemistry Letters. 5: 517-21. PMID 24900872 DOI: 10.1021/ml400501x  0.44
2014 Du X, Dransfield PJ, Lin DC, Wong S, Wang Y, Wang Z, Kohn T, Yu M, Brown SP, Vimolratana M, Zhu L, Li AR, Su Y, Jiao X, Liu JJ, et al. Improving the Pharmacokinetics of GPR40/FFA1 Full Agonists. Acs Medicinal Chemistry Letters. 5: 384-9. PMID 24900845 DOI: 10.1021/ml4005123  0.44
2014 Courter JR, Abdo M, Brown SP, Tucker MJ, Hochstrasser RM, Smith AB. The design and synthesis of alanine-rich α-helical peptides constrained by an S,S-tetrazine photochemical trigger: a fragment union approach. The Journal of Organic Chemistry. 79: 759-68. PMID 24359446 DOI: 10.1021/jo402680v  0.32
2014 Brown SP, Taygerly JP. Small-molecule modulators of GPR40 (FFA1) Annual Reports in Medicinal Chemistry. 49: 77-86. DOI: 10.1016/B978-0-12-800167-7.00006-7  0.44
2014 Brown SP. Optogenetic approaches for deciphering the neural circuits of the cortex Optics Infobase Conference Papers.  1
2013 Wang Y, Liu JJ, Dransfield PJ, Zhu L, Wang Z, Du X, Jiao X, Su Y, Li AR, Brown SP, Kasparian A, Vimolratana M, Yu M, Pattaropong V, Houze JB, et al. Discovery and Optimization of Potent GPR40 Full Agonists Containing Tricyclic Spirocycles. Acs Medicinal Chemistry Letters. 4: 551-5. PMID 24900707 DOI: 10.1021/ml300427u  0.44
2013 Tucker MJ, Abdo M, Courter JR, Chen J, Brown SP, Smith AB, Hochstrasser RM. Nonequilibrium dynamics of helix reorganization observed by transient 2D IR spectroscopy. Proceedings of the National Academy of Sciences of the United States of America. 110: 17314-9. PMID 24106309 DOI: 10.1073/pnas.1311876110  0.32
2012 Brown SP, Dransfield PJ, Vimolratana M, Jiao X, Zhu L, Pattaropong V, Sun Y, Liu J, Luo J, Zhang J, Wong S, Zhuang R, Guo Q, Li F, Medina JC, et al. Discovery of AM-1638: A Potent and Orally Bioavailable GPR40/FFA1 Full Agonist. Acs Medicinal Chemistry Letters. 3: 726-30. PMID 24900539 DOI: 10.1021/ml300133f  0.44
2012 Luo J, Swaminath G, Brown SP, Zhang J, Guo Q, Chen M, Nguyen K, Tran T, Miao L, Dransfield PJ, Vimolratana M, Houze JB, Wong S, Toteva M, Shan B, et al. A potent class of GPR40 full agonists engages the enteroinsular axis to promote glucose control in rodents. Plos One. 7: e46300. PMID 23056280 DOI: 10.1371/journal.pone.0046300  0.44
2012 Lin DC, Guo Q, Luo J, Zhang J, Nguyen K, Chen M, Tran T, Dransfield PJ, Brown SP, Houze J, Vimolratana M, Jiao XY, Wang Y, Birdsall NJ, Swaminath G. Identification and pharmacological characterization of multiple allosteric binding sites on the free fatty acid 1 receptor. Molecular Pharmacology. 82: 843-59. PMID 22859723 DOI: 10.1124/mol.112.079640  0.44
2012 Abdo M, Brown SP, Courter JR, Tucker MJ, Hochstrasser RM, Smith AB. Design, synthesis, and photochemical validation of peptide linchpins containing the S,S-tetrazine phototrigger. Organic Letters. 14: 3518-21. PMID 22731895 DOI: 10.1021/ol301490h  0.32
2012 Arroyo S, Bennett C, Aziz D, Brown SP, Hestrin S. Prolonged disynaptic inhibition in the cortex mediated by slow, non-α7 nicotinic excitation of a specific subset of cortical interneurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 3859-64. PMID 22423106 DOI: 10.1523/JNEUROSCI.0115-12.2012  1
2012 Brown SP, Taygerly JP. Small-Molecule Antagonists of Bcl-2 Family Proteins Annual Reports in Medicinal Chemistry. 47: 253-266. DOI: 10.1016/B978-0-12-396492-2.00017-5  0.44
2011 Vimolratana M, Simard JL, Brown SP. Palladium-catalyzed amidation of 2-chloropyrimidines Tetrahedron Letters. 52: 1020-1022. DOI: 10.1016/j.tetlet.2010.12.088  0.44
2009 Brown SP, Hestrin S. Cell-type identity: a key to unlocking the function of neocortical circuits. Current Opinion in Neurobiology. 19: 415-21. PMID 19674891 DOI: 10.1016/j.conb.2009.07.011  1
2009 Brown SP, Hestrin S. Intracortical circuits of pyramidal neurons reflect their long-range axonal targets. Nature. 457: 1133-6. PMID 19151698 DOI: 10.1038/nature07658  1
2004 Brown SP, Safo PK, Regehr WG. Endocannabinoids inhibit transmission at granule cell to Purkinje cell synapses by modulating three types of presynaptic calcium channels. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 5623-31. PMID 15201335 DOI: 10.1523/JNEUROSCI.0918-04.2004  1
2003 Brown SP, Brenowitz SD, Regehr WG. Brief presynaptic bursts evoke synapse-specific retrograde inhibition mediated by endogenous cannabinoids. Nature Neuroscience. 6: 1048-57. PMID 14502290 DOI: 10.1038/nn1126  1
2002 Rockhill RL, Daly FJ, MacNeil MA, Brown SP, Masland RH. The diversity of ganglion cells in a mammalian retina. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 3831-43. PMID 11978858  1
2001 Brown SP, Masland RH. Spatial scale and cellular substrate of contrast adaptation by retinal ganglion cells. Nature Neuroscience. 4: 44-51. PMID 11135644 DOI: 10.1038/82888  1
2000 Brown SP, He S, Masland RH. Receptive field microstructure and dendritic geometry of retinal ganglion cells. Neuron. 27: 371-83. PMID 10985356  1
1999 Brown SP, Masland RH. Costratification of a population of bipolar cells with the direction-selective circuitry of the rabbit retina. The Journal of Comparative Neurology. 408: 97-106. PMID 10331582 DOI: 10.1002/(SICI)1096-9861(19990524)408:1<97::AID-CNE7>3.0.CO;2-P  1
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