Seth Blackshaw - Publications

Affiliations: 
Johns Hopkins University School of Medicine, Baltimore, MD, United States 
Area:
Cell fate specification
Website:
http://neuroscience.jhu.edu/SethBlackshaw.php

139 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Pitarresi JR, Liu X, Avendano A, Thies KA, Sizemore GM, Hammer AM, Hildreth BE, Wang DJ, Steck SA, Donohue S, Cuitiño MC, Kladney RD, Mace TA, Chang JJ, Ennis CS, ... ... Blackshaw S, et al. Disruption of stromal hedgehog signaling initiates RNF5-mediated proteasomal degradation of PTEN and accelerates pancreatic tumor growth. Life Science Alliance. 1: e201800190. PMID 30456390 DOI: 10.26508/lsa.201800190  0.32
2018 Newman EA, Wu D, Taketo MM, Zhang J, Blackshaw S. Canonical Wnt signaling regulates patterning, differentiation and nucleogenesis in mouse hypothalamus and prethalamus. Developmental Biology. PMID 30063881 DOI: 10.1016/j.ydbio.2018.07.021  0.92
2018 Bedont JL, Rohr KE, Bathini A, Hattar S, Blackshaw S, Sehgal A, Evans JA. Asymmetric vasopressin signaling spatially organizes the master circadian clock. The Journal of Comparative Neurology. PMID 29931690 DOI: 10.1002/cne.24478  0.92
2018 Newman EA, Kim DW, Wan J, Wang J, Qian J, Blackshaw S. Foxd1 is required for terminal differentiation of anterior hypothalamic neuronal subtypes. Developmental Biology. PMID 29679559 DOI: 10.1016/j.ydbio.2018.04.012  0.92
2018 de Melo J, Clark BS, Venkataraman A, Shiau F, Zibetti C, Blackshaw S. Ldb1 and Rnf12-dependent regulation of Lhx2 controls the relative balance between neurogenesis and gliogenesis in retina. Development (Cambridge, England). PMID 29650591 DOI: 10.1242/dev.159970  1
2018 Venkataraman A, Yang K, Irizarry J, Mackiewicz M, Mita P, Kuang Z, Xue L, Ghosh D, Liu S, Ramos P, Hu S, Bayron Kain D, Keegan S, Saul R, Colantonio S, ... ... Blackshaw S, et al. A toolbox of immunoprecipitation-grade monoclonal antibodies to human transcription factors. Nature Methods. PMID 29638227 DOI: 10.1038/nmeth.4632  1
2018 Wang J, Zibetti C, Shang P, Sripathi SR, Zhang P, Cano M, Hoang T, Xia S, Ji H, Merbs SL, Zack DJ, Handa JT, Sinha D, Blackshaw S, Qian J. ATAC-Seq analysis reveals a widespread decrease of chromatin accessibility in age-related macular degeneration. Nature Communications. 9: 1364. PMID 29636475 DOI: 10.1038/s41467-018-03856-y  0.8
2018 Uzoma I, Hu J, Cox E, Xia S, Zhou J, Rho HS, Guzzo C, Paul C, Ajala O, Goodwin CR, Jeong J, Moore C, Zhang H, Meluh P, Blackshaw S, et al. Global Identification of SUMO Substrates Reveals Crosstalk between SUMOylation and Phosphorylation Promotes Cell Migration. Molecular & Cellular Proteomics : McP. PMID 29438996 DOI: 10.1074/mcp.RA117.000014  0.76
2018 de Melo J, Blackshaw S. In Vivo Electroporation of Developing Mouse Retina. Methods in Molecular Biology (Clifton, N.J.). 1715: 101-111. PMID 29188509 DOI: 10.1007/978-1-4939-7522-8_8  1
2017 Aleen Remez L, Onishi A, Menuchin-Lasowski Y, Biran A, Blackshaw S, Wahlin KJ, Zack DJ, Ashery-Padan R. Pax6 is essential for the generation of late-born retinal neurons and for inhibition of photoreceptor-fate during late stages of retinogenesis. Developmental Biology. PMID 28993200 DOI: 10.1016/j.ydbio.2017.09.030  0.8
2017 Liu K, Kim J, Kim DW, Stephanie Zhang Y, Bao H, Denaxa M, Lim SA, Kim E, Liu C, Wickersham IR, Pachnis V, Hattar S, Song J, Brown SP, Blackshaw S. Corrigendum: Lhx6-positive GABA-releasing neurons of the zona incerta promote sleep. Nature. PMID 28953871 DOI: 10.1038/nature24274  0.52
2017 Liu K, Kim J, Kim DW, Zhang YS, Bao H, Denaxa M, Lim SA, Kim E, Liu C, Wickersham IR, Pachinis V, Hattar S, Song J, Brown SP, Blackshaw S. Lhx6-positive GABA-releasing neurons of the zona incerta promote sleep. Nature. PMID 28847002 DOI: 10.1038/nature23663  0.52
2017 Clark BS, Blackshaw S. Understanding the Role of lncRNAs in Nervous System Development. Advances in Experimental Medicine and Biology. 1008: 253-282. PMID 28815543 DOI: 10.1007/978-981-10-5203-3_9  0.96
2017 Liu S, Zibetti C, Wan J, Wang G, Blackshaw S, Qian J. Assessing the model transferability for prediction of transcription factor binding sites based on chromatin accessibility. Bmc Bioinformatics. 18: 355. PMID 28750606 DOI: 10.1186/s12859-017-1769-7  0.8
2017 Cox E, Hwang W, Uzoma I, Hu J, Guzzo C, Jeong J, Matunis M, Qian J, Zhu H, Blackshaw S. Global analysis of SUMO-binding proteins identifies SUMOylation as a key regulator of the INO80 chromatin remodeling complex. Molecular & Cellular Proteomics : McP. PMID 28254775 DOI: 10.1074/mcp.M116.063719  0.76
2017 Barry G, Briggs JA, Hwang DW, Nayler SP, Fortuna PR, Jonkhout N, Dachet F, Maag JL, Mestdagh P, Singh EM, Avesson L, Kaczorowski DC, Ozturk E, Jones NC, Vetter I, ... ... Blackshaw S, et al. The long non-coding RNA NEAT1 is responsive to neuronal activity and is associated with hyperexcitability states. Scientific Reports. 7: 40127. PMID 28054653 DOI: 10.1038/srep40127  0.36
2016 Bedont JL, LeGates TA, Buhr E, Bathini A, Ling JP, Bell B, Wu MN, Wong PC, Van Gelder RN, Mongrain V, Hattar S, Blackshaw S. An LHX1-Regulated Transcriptional Network Controls Sleep/Wake Coupling and Thermal Resistance of the Central Circadian Clockworks. Current Biology : Cb. PMID 28017605 DOI: 10.1016/j.cub.2016.11.008  0.92
2016 Wang Y, An R, Umanah GK, Park H, Nambiar K, Eacker SM, Kim B, Bao L, Harraz MM, Chang C, Chen R, Wang JE, Kam TI, Jeong JS, Xie Z, ... ... Blackshaw S, et al. A nuclease that mediates cell death induced by DNA damage and poly(ADP-ribose) polymerase-1. Science (New York, N.Y.). 354. PMID 27846469 DOI: 10.1126/science.aad6872  0.76
2016 Gueta K, David A, Cohen T, Menuchin-Lasowski Y, Nobel H, Narkis G, Li L, Love P, de Melo J, Blackshaw S, Westphal H, Ashery-Padan R. The stage-dependent roles of Ldb1 and functional redundancy with Ldb2 in mammalian retinogenesis. Development (Cambridge, England). PMID 27697904 DOI: 10.1242/dev.129734  1
2016 Blackshaw S, Venkataraman A, Irizarry J, Yang K, Anderson S, Campbell E, Gatlin CL, Freeman NL, Basavappa R, Stewart R, Loss MA, Pino I, Zhu H, Bader JS. The NIH Protein Capture Reagents Program (PCRP): a standardized protein affinity reagent toolbox. Nature Methods. 13: 805-806. PMID 27684578 DOI: 10.1038/nmeth.4013  1
2016 Thein T, de Melo J, Zibetti C, Clark BS, Juarez F, Blackshaw S. Control of lens development by Lhx2-regulated neuroretinal FGFs. Development (Cambridge, England). PMID 27633990 DOI: 10.1242/dev.137760  1
2016 de Melo J, Clark BS, Blackshaw S. Multiple intrinsic factors act in concert with Lhx2 to direct retinal gliogenesis. Scientific Reports. 6: 32757. PMID 27605455 DOI: 10.1038/srep32757  1
2016 Li H, Edie S, Klinedinst D, Jeong JS, Blackshaw S, Maslen CL, Reeves RH. Penetrance of Congenital Heart Disease in a Mouse Model of Down Syndrome Depends on a Trisomic Potentiator of a Disomic Modifier. Genetics. PMID 27029737 DOI: 10.1534/genetics.116.188045  1
2016 Lagerlöf O, Slocomb JE, Hong I, Aponte Y, Blackshaw S, Hart GW, Huganir RL. The nutrient sensor OGT in PVN neurons regulates feeding. Science (New York, N.Y.). 351: 1293-6. PMID 26989246 DOI: 10.1126/science.aad5494  1
2016 de Melo J, Zibetti C, Clark BS, Hwang W, Miranda-Angulo AL, Qian J, Blackshaw S. Lhx2 Is an Essential Factor for Retinal Gliogenesis and Notch Signaling. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 2391-405. PMID 26911688 DOI: 10.1523/JNEUROSCI.3145-15.2016  1
2015 Freyburger M, Pierre A, Paquette G, Bélanger-Nelson E, Bedont J, Gaudreault PO, Drolet G, Laforest S, Blackshaw S, Cermakian N, Doucet G, Mongrain V. EphA4 is Involved in Sleep Regulation But Not in the Electrophysiological Response to Sleep Deprivation. Sleep. PMID 26612390 DOI: 10.5665/sleep.5538  1
2015 Bedont JL, Blackshaw S. Constructing the suprachiasmatic nucleus: a watchmaker's perspective on the central clockworks. Frontiers in Systems Neuroscience. 9: 74. PMID 26005407 DOI: 10.3389/fnsys.2015.00074  0.92
2015 Cox E, Uzoma I, Guzzo C, Jeong JS, Matunis M, Blackshaw S, Zhu H. Identification of SUMO E3 ligase-specific substrates using the HuProt human proteome microarray. Methods in Molecular Biology (Clifton, N.J.). 1295: 455-63. PMID 25820740 DOI: 10.1007/978-1-4939-2550-6_32  1
2015 Bedont JL, Newman EA, Blackshaw S. Patterning, specification, and differentiation in the developing hypothalamus. Wiley Interdisciplinary Reviews. Developmental Biology. PMID 25820448 DOI: 10.1002/wdev.187  1
2015 Mattar P, Ericson J, Blackshaw S, Cayouette M. A conserved regulatory logic controls temporal identity in mouse neural progenitors. Neuron. 85: 497-504. PMID 25654255 DOI: 10.1016/j.neuron.2014.12.052  1
2015 Bedont JL, Blackshaw S. Constructing the suprachiasmatic nucleus: A watchmaker's perspective on the central clockworks Frontiers in Systems Neuroscience. 9: 1-21. DOI: 10.3389/fnsys.2015.00074  1
2015 Shimogori T, Blackshaw S. Large-scale ISH on mouse brain sections for systematic gene expression analysis in developing mouse diencephalon Neuromethods. 99: 207-220. DOI: 10.1007/978-1-4939-2303-8_10  1
2014 Salvatierra J, Lee DA, Zibetti C, Duran-Moreno M, Yoo S, Newman EA, Wang H, Bedont JL, de Melo J, Miranda-Angulo AL, Gil-Perotin S, Garcia-Verdugo JM, Blackshaw S. The LIM homeodomain factor Lhx2 is required for hypothalamic tanycyte specification and differentiation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 16809-20. PMID 25505333 DOI: 10.1523/JNEUROSCI.1711-14.2014  1
2014 Jung JG, Stoeck A, Guan B, Wu RC, Zhu H, Blackshaw S, Shih IeM, Wang TL. Notch3 interactome analysis identified WWP2 as a negative regulator of Notch3 signaling in ovarian cancer. Plos Genetics. 10: e1004751. PMID 25356737 DOI: 10.1371/journal.pgen.1004751  1
2014 Ma TM, Paul BD, Fu C, Hu S, Zhu H, Blackshaw S, Wolosker H, Snyder SH. Serine racemase regulated by binding to stargazin and PSD-95: potential N-methyl-D-aspartate-α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (NMDA-AMPA) glutamate neurotransmission cross-talk. The Journal of Biological Chemistry. 289: 29631-41. PMID 25164819 DOI: 10.1074/jbc.M114.571604  1
2014 Guzzo CM, Ringel A, Cox E, Uzoma I, Zhu H, Blackshaw S, Wolberger C, Matunis MJ. Characterization of the SUMO-binding activity of the myeloproliferative and mental retardation (MYM)-type zinc fingers in ZNF261 and ZNF198. Plos One. 9: e105271. PMID 25133527 DOI: 10.1371/journal.pone.0105271  1
2014 Lee DA, Yoo S, Pak T, Salvatierra J, Velarde E, Aja S, Blackshaw S. Dietary and sex-specific factors regulate hypothalamic neurogenesis in young adult mice. Frontiers in Neuroscience. 8: 157. PMID 24982613 DOI: 10.3389/fnins.2014.00157  1
2014 Clark BS, Blackshaw S. Long non-coding RNA-dependent transcriptional regulation in neuronal development and disease. Frontiers in Genetics. 5: 164. PMID 24936207 DOI: 10.3389/fgene.2014.00164  1
2014 Bedont JL, LeGates TA, Slat EA, Byerly MS, Wang H, Hu J, Rupp AC, Qian J, Wong GW, Herzog ED, Hattar S, Blackshaw S. Lhx1 controls terminal differentiation and circadian function of the suprachiasmatic nucleus. Cell Reports. 7: 609-22. PMID 24767996 DOI: 10.1016/j.celrep.2014.03.060  1
2014 Pak T, Yoo S, Miranda-Angulo AL, Miranda-Angulo AM, Wang H, Blackshaw S. Rax-CreERT2 knock-in mice: a tool for selective and conditional gene deletion in progenitor cells and radial glia of the retina and hypothalamus. Plos One. 9: e90381. PMID 24699247 DOI: 10.1371/journal.pone.0090381  1
2014 Liu S, Lamaze A, Liu Q, Tabuchi M, Yang Y, Fowler M, Bharadwaj R, Zhang J, Bedont J, Blackshaw S, Lloyd TE, Montell C, Sehgal A, Koh K, Wu MN. WIDE AWAKE mediates the circadian timing of sleep onset. Neuron. 82: 151-66. PMID 24631345 DOI: 10.1016/j.neuron.2014.01.040  0.52
2014 Lee DA, Blackshaw S. Feed your head: neurodevelopmental control of feeding and metabolism. Annual Review of Physiology. 76: 197-223. PMID 24274739 DOI: 10.1146/annurev-physiol-021113-170347  1
2014 Lee YI, Giovinazzo D, Kang HC, Lee Y, Jeong JS, Doulias PT, Xie Z, Hu J, Ghasemi M, Ischiropoulos H, Qian J, Zhu H, Blackshaw S, Dawson VL, Dawson TM. Protein microarray characterization of the S-nitrosoproteome. Molecular & Cellular Proteomics : McP. 13: 63-72. PMID 24105792 DOI: 10.1074/mcp.M113.032235  1
2014 Miranda-Angulo AL, Byerly MS, Mesa J, Wang H, Blackshaw S. Rax regulates hypothalamic tanycyte differentiation and barrier function in mice. The Journal of Comparative Neurology. 522: 876-99. PMID 23939786 DOI: 10.1002/cne.23451  1
2014 Barry G, Briggs JA, Vanichkina DP, Poth EM, Beveridge NJ, Ratnu VS, Nayler SP, Nones K, Hu J, Bredy TW, Nakagawa S, Rigo F, Taft RJ, Cairns MJ, Blackshaw S, et al. The long non-coding RNA Gomafu is acutely regulated in response to neuronal activation and involved in schizophrenia-associated alternative splicing. Molecular Psychiatry. 19: 486-94. PMID 23628989 DOI: 10.1038/mp.2013.45  1
2014 Pak T, Yoo S, Miranda-Angulo AL, Wang H, Blackshaw S. Rax-CreERT2 knock-in mice: A tool for selective and conditional gene deletion in progenitor cells and radial glia of the retina and hypothalamus (PLoS ONE 9, 4 (e90381) DOI:10.1371/journal.pone.0090381) Plos One. 9. DOI: 10.1371/journal.pone.0102875  1
2013 Byerly MS, Swanson RD, Wong GW, Blackshaw S. Stage-specific inhibition of TrkB activity leads to long-lasting and sexually dimorphic effects on body weight and hypothalamic gene expression. Plos One. 8: e80781. PMID 24312242 DOI: 10.1371/journal.pone.0080781  1
2013 Lee DA, Salvatierra J, Velarde E, Wong J, Ford EC, Blackshaw S. Functional interrogation of adult hypothalamic neurogenesis with focal radiological inhibition. Journal of Visualized Experiments : Jove. e50716. PMID 24300415 DOI: 10.3791/50716  1
2013 Donnelly CJ, Zhang PW, Pham JT, Haeusler AR, Heusler AR, Mistry NA, Vidensky S, Daley EL, Poth EM, Hoover B, Fines DM, Maragakis N, Tienari PJ, Petrucelli L, Traynor BJ, ... ... Blackshaw S, et al. RNA toxicity from the ALS/FTD C9ORF72 expansion is mitigated by antisense intervention. Neuron. 80: 415-28. PMID 24139042 DOI: 10.1016/j.neuron.2013.10.015  1
2013 Byerly MS, Swanson RD, Wong GW, Blackshaw S. Estrogen-related receptor β deficiency alters body composition and response to restraint stress. Bmc Physiology. 13: 10. PMID 24053666 DOI: 10.1186/1472-6793-13-10  1
2013 Chen Y, Yang LN, Cheng L, Tu S, Guo SJ, Le HY, Xiong Q, Mo R, Li CY, Jeong JS, Jiang L, Blackshaw S, Bi LJ, Zhu H, Tao SC, et al. Bcl2-associated athanogene 3 interactome analysis reveals a new role in modulating proteasome activity. Molecular & Cellular Proteomics : McP. 12: 2804-19. PMID 23824909 DOI: 10.1074/mcp.M112.025882  1
2013 Roy A, de Melo J, Chaturvedi D, Thein T, Cabrera-Socorro A, Houart C, Meyer G, Blackshaw S, Tole S. LHX2 is necessary for the maintenance of optic identity and for the progression of optic morphogenesis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 6877-84. PMID 23595746 DOI: 10.1523/JNEUROSCI.4216-12.2013  1
2013 Byerly MS, Swanson RD, Semsarzadeh NN, McCulloh PS, Kwon K, Aja S, Moran TH, Wong GW, Blackshaw S. Identification of hypothalamic neuron-derived neurotrophic factor as a novel factor modulating appetite. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 304: R1085-95. PMID 23576617 DOI: 10.1152/ajpregu.00368.2012  1
2013 Newman RH, Hu J, Rho HS, Xie Z, Woodard C, Neiswinger J, Cooper C, Shirley M, Clark HM, Hu S, Hwang W, Jeong JS, Wu G, Lin J, Gao X, ... ... Blackshaw S, et al. Construction of human activity-based phosphorylation networks. Molecular Systems Biology. 9: 655. PMID 23549483 DOI: 10.1038/msb.2013.12  1
2013 Byerly MS, Al Salayta M, Swanson RD, Kwon K, Peterson JM, Wei Z, Aja S, Moran TH, Blackshaw S, Wong GW. Estrogen-related receptor β deletion modulates whole-body energy balance via estrogen-related receptor γ and attenuates neuropeptide Y gene expression. The European Journal of Neuroscience. 37: 1033-47. PMID 23360481 DOI: 10.1111/ejn.12122  1
2013 Blackshaw S. High-throughput RNA in situ hybridization in mouse retina. Methods in Molecular Biology (Clifton, N.J.). 935: 215-26. PMID 23150371 DOI: 10.1007/978-1-62703-080-9_15  1
2013 Donnelly CJ, Zhang PW, Pham JT, Haeusler AR, Mistry NA, Vidensky S, Daley EL, Poth EM, Hoover B, Fines DM, Maragakis N, Tienari PJ, Petrucelli L, Traynor BJ, Wang J, ... ... Blackshaw S, et al. RNA Toxicity from the ALS/FTD C9ORF72 expansion is mitigated by antisense intervention [Neuron, 79, (September 18, 2013), 1222-1231] Neuron. 80: 1102. DOI: 10.1016/j.neuron.2013.10.055  1
2012 Lee DA, Blackshaw S. Functional implications of hypothalamic neurogenesis in the adult mammalian brain. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 30: 615-21. PMID 22867732 DOI: 10.1016/j.ijdevneu.2012.07.003  1
2012 Lee DA, Blackshaw S. WITHDRAWN: Functional implications of hypothalamic neurogenesis in the adult mammalian brain. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. PMID 22814121 DOI: 10.1016/j.ijdevneu.2012.03.300  0.92
2012 Hu CJ, Song G, Huang W, Liu GZ, Deng CW, Zeng HP, Wang L, Zhang FC, Zhang X, Jeong JS, Blackshaw S, Jiang LZ, Zhu H, Wu L, Li YZ. Identification of new autoantigens for primary biliary cirrhosis using human proteome microarrays. Molecular & Cellular Proteomics : McP. 11: 669-80. PMID 22647870 DOI: 10.1074/mcp.M111.015529  1
2012 Lee DA, Bedont JL, Pak T, Wang H, Song J, Miranda-Angulo A, Takiar V, Charubhumi V, Balordi F, Takebayashi H, Aja S, Ford E, Fishell G, Blackshaw S. Tanycytes of the hypothalamic median eminence form a diet-responsive neurogenic niche. Nature Neuroscience. 15: 700-2. PMID 22446882 DOI: 10.1038/nn.3079  1
2012 Chi Z, Zhang J, Tokunaga A, Harraz MM, Byrne ST, Dolinko A, Xu J, Blackshaw S, Gaiano N, Dawson TM, Dawson VL. Botch promotes neurogenesis by antagonizing Notch. Developmental Cell. 22: 707-20. PMID 22445366 DOI: 10.1016/j.devcel.2012.02.011  1
2012 de Melo J, Miki K, Rattner A, Smallwood P, Zibetti C, Hirokawa K, Monuki ES, Campochiaro PA, Blackshaw S. Injury-independent induction of reactive gliosis in retina by loss of function of the LIM homeodomain transcription factor Lhx2. Proceedings of the National Academy of Sciences of the United States of America. 109: 4657-62. PMID 22393024 DOI: 10.1073/pnas.1107488109  1
2012 Jeong JS, Jiang L, Albino E, Marrero J, Rho HS, Hu J, Hu S, Vera C, Bayron-Poueymiroy D, Rivera-Pacheco ZA, Ramos L, Torres-Castro C, Qian J, Bonaventura J, Boeke JD, ... ... Blackshaw S, et al. Rapid identification of monospecific monoclonal antibodies using a human proteome microarray. Molecular & Cellular Proteomics : McP. 11: O111.016253. PMID 22307071 DOI: 10.1074/mcp.O111.016253  0.76
2012 Tarrant MK, Rho HS, Xie Z, Jiang YL, Gross C, Culhane JC, Yan G, Qian J, Ichikawa Y, Matsuoka T, Zachara N, Etzkorn FA, Hart GW, Jeong JS, Blackshaw S, et al. Regulation of CK2 by phosphorylation and O-GlcNAcylation revealed by semisynthesis. Nature Chemical Biology. 8: 262-9. PMID 22267120 DOI: 10.1038/nchembio.771  1
2011 Reece-Hoyes JS, Barutcu AR, McCord RP, Jeong JS, Jiang L, MacWilliams A, Yang X, Salehi-Ashtiani K, Hill DE, Blackshaw S, Zhu H, Dekker J, Walhout AJ. Yeast one-hybrid assays for gene-centered human gene regulatory network mapping. Nature Methods. 8: 1050-2. PMID 22037702 DOI: 10.1038/nmeth.1764  1
2011 Rapicavoli NA, Poth EM, Zhu H, Blackshaw S. The long noncoding RNA Six3OS acts in trans to regulate retinal development by modulating Six3 activity. Neural Development. 6: 32. PMID 21936910 DOI: 10.1186/1749-8104-6-32  1
2011 Blackshaw S. We contain multitudes: the protean face of retinoblastoma. Cancer Cell. 20: 137-8. PMID 21840479 DOI: 10.1016/j.ccr.2011.08.002  1
2011 de Melo J, Blackshaw S. In vivo electroporation of developing mouse retina. Journal of Visualized Experiments : Jove. PMID 21730944 DOI: 10.3791/2847  1
2011 de Melo J, Peng GH, Chen S, Blackshaw S. The Spalt family transcription factor Sall3 regulates the development of cone photoreceptors and retinal horizontal interneurons. Development (Cambridge, England). 138: 2325-36. PMID 21558380 DOI: 10.1242/dev.061846  1
2011 Hu S, Xie Z, Blackshaw S, Qian J, Zhu H. Characterization of protein-DNA interactions using protein microarrays. Cold Spring Harbor Protocols. 2011: pdb.prot5614. PMID 21536762 DOI: 10.1101/pdb.prot5614  1
2011 Xie Z, Hu S, Qian J, Blackshaw S, Zhu H. Systematic characterization of protein-DNA interactions. Cellular and Molecular Life Sciences : Cmls. 68: 1657-68. PMID 21207099 DOI: 10.1007/s00018-010-0617-y  1
2011 Yuge K, Kataoka A, Yoshida AC, Itoh D, Aggarwal M, Mori S, Blackshaw S, Shimogori T. Region-specific gene expression in early postnatal mouse thalamus. The Journal of Comparative Neurology. 519: 544-61. PMID 21192083 DOI: 10.1002/cne.22532  1
2011 Suzuki-Hirano A, Ogawa M, Kataoka A, Yoshida AC, Itoh D, Ueno M, Blackshaw S, Shimogori T. Dynamic spatiotemporal gene expression in embryonic mouse thalamus. The Journal of Comparative Neurology. 519: 528-43. PMID 21192082 DOI: 10.1002/cne.22531  1
2011 Hu S, Xie Z, Qian J, Blackshaw S, Zhu H. Functional protein microarray technology. Wiley Interdisciplinary Reviews. Systems Biology and Medicine. 3: 255-68. PMID 20872749 DOI: 10.1002/wsbm.118  1
2010 Blackshaw S, Scholpp S, Placzek M, Ingraham H, Simerly R, Shimogori T. Molecular pathways controlling development of thalamus and hypothalamus: from neural specification to circuit formation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 14925-30. PMID 21068293 DOI: 10.1523/JNEUROSCI.4499-10.2010  1
2010 Onishi A, Peng GH, Chen S, Blackshaw S. Pias3-dependent SUMOylation controls mammalian cone photoreceptor differentiation. Nature Neuroscience. 13: 1059-65. PMID 20729845 DOI: 10.1038/nn.2618  1
2010 Aggarwal M, Mori S, Shimogori T, Blackshaw S, Zhang J. Three-dimensional diffusion tensor microimaging for anatomical characterization of the mouse brain. Magnetic Resonance in Medicine. 64: 249-61. PMID 20577980 DOI: 10.1002/mrm.22426  1
2010 Onishi A, Peng GH, Poth EM, Lee DA, Chen J, Alexis U, de Melo J, Chen S, Blackshaw S. The orphan nuclear hormone receptor ERRbeta controls rod photoreceptor survival. Proceedings of the National Academy of Sciences of the United States of America. 107: 11579-84. PMID 20534447 DOI: 10.1073/pnas.1000102107  1
2010 Rapicavoli NA, Poth EM, Blackshaw S. The long noncoding RNA RNCR2 directs mouse retinal cell specification. Bmc Developmental Biology. 10: 49. PMID 20459797 DOI: 10.1186/1471-213X-10-49  1
2010 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S. A genomic atlas of mouse hypothalamic development. Nature Neuroscience. 13: 767-75. PMID 20436479 DOI: 10.1038/nn.2545  1
2010 Xie Z, Hu S, Blackshaw S, Zhu H, Qian J. hPDI: a database of experimental human protein-DNA interactions. Bioinformatics (Oxford, England). 26: 287-9. PMID 19900953 DOI: 10.1093/bioinformatics/btp631  1
2009 Byerly MS, Blackshaw S. Vertebrate retina and hypothalamus development. Wiley Interdisciplinary Reviews. Systems Biology and Medicine. 1: 380-9. PMID 20836003 DOI: 10.1002/wsbm.22  1
2009 Hu S, Xie Z, Onishi A, Yu X, Jiang L, Lin J, Rho HS, Woodard C, Wang H, Jeong JS, Long S, He X, Wade H, Blackshaw S, Qian J, et al. Profiling the human protein-DNA interactome reveals ERK2 as a transcriptional repressor of interferon signaling. Cell. 139: 610-22. PMID 19879846 DOI: 10.1016/j.cell.2009.08.037  1
2009 Kim JS, Coon SL, Weller JL, Blackshaw S, Rath MF, Møller M, Klein DC. Muscleblind-like 2: circadian expression in the mammalian pineal gland is controlled by an adrenergic-cAMP mechanism. Journal of Neurochemistry. 110: 756-64. PMID 19457059 DOI: 10.1111/j.1471-4159.2009.06184.x  1
2009 Rapicavoli NA, Blackshaw S. New meaning in the message: noncoding RNAs and their role in retinal development. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 238: 2103-14. PMID 19191220 DOI: 10.1002/dvdy.21844  1
2009 Onishi A, Peng GH, Hsu C, Alexis U, Chen S, Blackshaw S. Pias3-dependent SUMOylation directs rod photoreceptor development. Neuron. 61: 234-46. PMID 19186166 DOI: 10.1016/j.neuron.2008.12.006  1
2008 Huang AS, Lee DA, Blackshaw S. D-Aspartate and D-aspartate oxidase show selective and developmentally dynamic localization in mouse retina. Experimental Eye Research. 86: 704-9. PMID 18314103 DOI: 10.1016/j.exer.2008.01.015  1
2007 Blackshaw S, St Croix B, Polyak K, Kim JB, Cai L. Serial analysis of gene expression (SAGE): experimental method and data analysis. Current Protocols in Human Genetics / Editorial Board, Jonathan L. Haines ... [Et Al.]. Unit 11.7. PMID 18428405 DOI: 10.1002/0471142905.hg1107s53  1
2007 Blackshaw S, Croix BS, Polyak K, Kim JB, Cai L. Serial analysis of gene expression (SAGE): experimental method and data analysis. Current Protocols in Molecular Biology / Edited by Frederick M. Ausubel ... [Et Al.]. Unit 25B.6. PMID 18265400 DOI: 10.1002/0471142727.mb25b06s80  1
2006 Weil ZM, Huang AS, Beigneux A, Kim PM, Molliver ME, Blackshaw S, Young SG, Nelson RJ, Snyder SH. Behavioural alterations in male mice lacking the gene for D-aspartate oxidase. Behavioural Brain Research. 171: 295-302. PMID 16725213 DOI: 10.1016/j.bbr.2006.04.008  1
2006 Huang AS, Beigneux A, Weil ZM, Kim PM, Molliver ME, Blackshaw S, Nelson RJ, Young SG, Snyder SH. D-aspartate regulates melanocortin formation and function: behavioral alterations in D-aspartate oxidase-deficient mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 2814-9. PMID 16525061 DOI: 10.1523/JNEUROSCI.5060-05.2006  1
2006 Blackshaw S. Genomics Retinal Development. 325-341. DOI: 10.1017/CBO9780511541629.018  1
2005 Kim JS, Coon SL, Blackshaw S, Cepko CL, Møller M, Mukda S, Zhao WQ, Charlton CG, Klein DC. Methionine adenosyltransferase:adrenergic-cAMP mechanism regulates a daily rhythm in pineal expression. The Journal of Biological Chemistry. 280: 677-84. PMID 15504733 DOI: 10.1074/jbc.M408438200  1
2004 Cai L, Huang H, Blackshaw S, Liu JS, Cepko C, Wong WH. Clustering analysis of SAGE data using a Poisson approach. Genome Biology. 5: R51. PMID 15239836 DOI: 10.1186/gb-2004-5-7-r51  1
2004 Blackshaw S, Harpavat S, Trimarchi J, Cai L, Huang H, Kuo WP, Weber G, Lee K, Fraioli RE, Cho SH, Yung R, Asch E, Ohno-Machado L, Wong WH, Cepko CL. Genomic analysis of mouse retinal development. Plos Biology. 2: E247. PMID 15226823 DOI: 10.1371/journal.pbio.0020247  1
2004 Danoff SK, Taylor HE, Blackshaw S, Desiderio S. TFII-I, a candidate gene for Williams syndrome cognitive profile: parallels between regional expression in mouse brain and human phenotype. Neuroscience. 123: 931-8. PMID 14751286 DOI: 10.1016/j.neuroscience.2003.08.038  1
2003 Blackshaw S, Eliasson MJ, Sawa A, Watkins CC, Krug D, Gupta A, Arai T, Ferrante RJ, Snyder SH. Species, strain and developmental variations in hippocampal neuronal and endothelial nitric oxide synthase clarify discrepancies in nitric oxide-dependent synaptic plasticity. Neuroscience. 119: 979-90. PMID 12831857 DOI: 10.1016/S0306-4522(03)00217-3  1
2003 Blackshaw S, Kuo WP, Park PJ, Tsujikawa M, Gunnersen JM, Scott HS, Boon WM, Tan SS, Cepko CL. MicroSAGE is highly representative and reproducible but reveals major differences in gene expression among samples obtained from similar tissues. Genome Biology. 4: R17. PMID 12620102  1
2002 Sezen SF, Blackshaw S, Steiner JP, Burnett AL. FK506 binding protein 12 is expressed in rat penile innervation and upregulated after cavernous nerve injury. International Journal of Impotence Research. 14: 506-12. PMID 12494287 DOI: 10.1038/sj.ijir.3900919  1
2002 Blackshaw S, Cepko CL. Stem cells that know their place. Nature Neuroscience. 5: 1251-2. PMID 12447376 DOI: 10.1038/nn1202-1251  1
2002 Akey DT, Zhu X, Dyer M, Li A, Sorensen A, Blackshaw S, Fukuda-Kamitani T, Daiger SP, Craft CM, Kamitani T, Sohocki MM. The inherited blindness associated protein AIPL1 interacts with the cell cycle regulator protein NUB1. Human Molecular Genetics. 11: 2723-33. PMID 12374762  1
2002 Bowne SJ, Sullivan LS, Blanton SH, Cepko CL, Blackshaw S, Birch DG, Hughbanks-Wheaton D, Heckenlively JR, Daiger SP. Mutations in the inosine monophosphate dehydrogenase 1 gene (IMPDH1) cause the RP10 form of autosomal dominant retinitis pigmentosa. Human Molecular Genetics. 11: 559-68. PMID 11875050  1
2002 Blackshaw S, Livesey R. Applying genomics technologies to neural development. Current Opinion in Neurobiology. 12: 110-4. PMID 11861173 DOI: 10.1016/S0959-4388(02)00298-2  1
2002 Sharon D, Blackshaw S, Cepko CL, Dryja TP. Profile of the genes expressed in the human peripheral retina, macula, and retinal pigment epithelium determined through serial analysis of gene expression (SAGE). Proceedings of the National Academy of Sciences of the United States of America. 99: 315-20. PMID 11756676 DOI: 10.1073/pnas.012582799  1
2001 Kim JB, Blackshaw S. One-step enzymatic purification of PCR products for direct sequencing. Current Protocols in Human Genetics / Editorial Board, Jonathan L. Haines ... [Et Al.]. Unit 11.6. PMID 18428248 DOI: 10.1002/0471142905.hg1106s30  1
2001 Dorit RL, Ohara O, Hwang CB, Kim JB, Blackshaw S. Direct DNA sequencing of PCR products. Current Protocols in Molecular Biology / Edited by Frederick M. Ausubel ... [Et Al.]. Unit 15.2. PMID 18265116 DOI: 10.1002/0471142727.mb1502s56  1
2001 Blackshaw S, Fraioli RE, Furukawa T, Cepko CL. Comprehensive analysis of photoreceptor gene expression and the identification of candidate retinal disease genes. Cell. 107: 579-89. PMID 11733058 DOI: 10.1016/S0092-8674(01)00574-8  1
2000 Ye K, Hurt KJ, Wu FY, Fang M, Luo HR, Hong JJ, Blackshaw S, Ferris CD, Snyder SH. Pike. A nuclear gtpase that enhances PI3kinase activity and is regulated by protein 4.1N. Cell. 103: 919-30. PMID 11136977  1
2000 Law A, Doré S, Blackshaw S, Gauthier S, Quirion R. Alteration of expression levels of neuronal nitric oxide synthase and haem oxygenase-2 messenger RNA in the hippocampi and cortices of young adult and aged cognitively unimpaired and impaired Long-Evans rats. Neuroscience. 100: 769-75. PMID 11036210 DOI: 10.1016/S0306-4522(00)00316-X  1
2000 Watkins CC, Sawa A, Jaffrey S, Blackshaw S, Barrow RK, Snyder SH, Ferris CD. Insulin restores neuronal nitric oxide synthase expression and function that is lost in diabetic gastropathy The Journal of Clinical Investigation. 106: 803. PMID 10995791  1
2000 Doré S, Goto S, Sampei K, Blackshaw S, Hester LD, Ingi T, Sawa A, Traystman RJ, Koehler RC, Snyder SH. Heme oxygenase-2 acts to prevent neuronal death in brain cultures and following transient cerebral ischemia. Neuroscience. 99: 587-92. PMID 10974422 DOI: 10.1016/S0306-4522(00)00216-5  1
2000 Watkins CC, Sawa A, Jaffrey S, Blackshaw S, Barrow RK, Snyder SH, Ferris CD. Insulin restores neuronal nitric oxide synthase expression and function that is lost in diabetic gastropathy. The Journal of Clinical Investigation. 106: 373-84. PMID 10930440 DOI: 10.1172/JCI8273  1
2000 Sohoki MM, Browne SJ, Sullivan LS, Blackshaw S, Cepko CL, Payne AM, Bhattacharya SS, Khaliq S, Mehdi SQ, Birch DG, Harrison WR, Elder FF, Heckenlively JR, Daiger SP. Mutations in a new photoreceptor-pineal gene on 17p cause leber congenital amaurosis. Nat gen 2000;24:79-83 American Journal of Ophthalmology. 129: 834-5. PMID 10927016  1
2000 Blackshaw S, Sawa A, Sharp AH, Ross CA, Snyder SH, Khan AA. Type 3 inositol 1,4,5-trisphosphate receptor modulates cell death. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 14: 1375-9. PMID 10877830  1
2000 Pieper AA, Blackshaw S, Clements EE, Brat DJ, Krug DK, White AJ, Pinto-Garcia P, Favit A, Conover JR, Snyder SH, Verma A. Poly(ADP-ribosyl)ation basally activated by DNA strand breaks reflects glutamate-nitric oxide neurotransmission. Proceedings of the National Academy of Sciences of the United States of America. 97: 1845-50. PMID 10677544 DOI: 10.1073/pnas.97.4.1845  1
2000 Parra M, Gascard P, Walensky LD, Gimm JA, Blackshaw S, Chan N, Takakuwa Y, Berger T, Lee G, Chasis JA, Snyder SH, Mohandas N, Conboy JG. Molecular and functional characterization of protein 4.1B, a novel member of the protein 4.1 family with high level, focal expression in brain. The Journal of Biological Chemistry. 275: 3247-55. PMID 10652311 DOI: 10.1074/jbc.275.5.3247  1
2000 Sohocki MM, Bowne SJ, Sullivan LS, Blackshaw S, Cepko CL, Payne AM, Bhattacharya SS, Khaliq S, Qasim Mehdi S, Birch DG, Harrison WR, Elder FF, Heckenlively JR, Daiger SP. Mutations in a new photoreceptor-pineal gene on 17p cause Leber congenital amaurosis. Nature Genetics. 24: 79-83. PMID 10615133 DOI: 10.1038/71732  1
1999 Halleck MS, Lawler JF JR, Blackshaw S, Gao L, Nagarajan P, Hacker C, Pyle S, Newman JT, Nakanishi Y, Ando H, Weinstock D, Williamson P, Schlegel RA. Differential expression of putative transbilayer amphipath transporters. Physiological Genomics. 1: 139-50. PMID 11015572  1
1999 Doré S, Sampei K, Goto S, Alkayed NJ, Guastella D, Blackshaw S, Gallagher M, Traystman RJ, Hurn PD, Koehler RC, Snyder SH. Heme oxygenase-2 is neuroprotective in cerebral ischemia. Molecular Medicine (Cambridge, Mass.). 5: 656-63. PMID 10602774  1
1999 Borjigin J, Deng J, Wang MM, Li X, Blackshaw S, Snyder SH. Circadian rhythm of patched1 transcription in the pineal regulated by adrenergic stimulation and cAMP. The Journal of Biological Chemistry. 274: 35012-5. PMID 10574978 DOI: 10.1074/jbc.274.49.35012  1
1999 Wolosker H, Blackshaw S, Snyder SH. Serine racemase: a glial enzyme synthesizing D-serine to regulate glutamate-N-methyl-D-aspartate neurotransmission. Proceedings of the National Academy of Sciences of the United States of America. 96: 13409-14. PMID 10557334 DOI: 10.1073/pnas.96.23.13409  1
1999 Demas GE, Kriegsfeld LJ, Blackshaw S, Huang P, Gammie SC, Nelson RJ, Snyder SH. Elimination of aggressive behavior in male mice lacking endothelial nitric oxide synthase. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: RC30. PMID 10493775  1
1999 Walensky LD, Blackshaw S, Liao D, Watkins CC, Weier HU, Parra M, Huganir RL, Conboy JG, Mohandas N, Snyder SH. A novel neuron-enriched homolog of the erythrocyte membrane cytoskeletal protein 4.1. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 6457-67. PMID 10414974  1
1999 Sabatini DM, Barrow RK, Blackshaw S, Burnett PE, Lai MM, Field ME, Bahr BA, Kirsch J, Betz H, Snyder SH. Interaction of RAFT1 with gephyrin required for rapamycin-sensitive signaling. Science (New York, N.Y.). 284: 1161-4. PMID 10325225 DOI: 10.1126/science.284.5417.1161  1
1999 Blackshaw S, Snyder SH. Encephalopsin: a novel mammalian extraretinal opsin discretely localized in the brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 3681-90. PMID 10234000  1
1999 Pieper AA, Brat DJ, Krug DK, Watkins CC, Gupta A, Blackshaw S, Verma A, Wang ZQ, Snyder SH. Poly(ADP-ribose) polymerase-deficient mice are protected from streptozotocin-induced diabetes. Proceedings of the National Academy of Sciences of the United States of America. 96: 3059-64. PMID 10077636 DOI: 10.1073/pnas.96.6.3059  1
1999 Kriegsfeld LJ, Eliasson MJ, Demas GE, Blackshaw S, Dawson TM, Nelson RJ, Snyder SH. Nocturnal motor coordination deficits in neuronal nitric oxide synthase knock-out mice. Neuroscience. 89: 311-5. PMID 10077313 DOI: 10.1016/S0306-4522(98)00614-9  1
1998 Walensky LD, Shi ZT, Blackshaw S, DeVries AC, Demas GE, Gascard P, Nelson RJ, Conboy JG, Rubin EM, Snyder SH, Mohandas N. Neurobehavioral deficits in mice lacking the erythrocyte membrane cytoskeletal protein 4.1. Current Biology : Cb. 8: 1269-72. PMID 9822582  1
1998 Lai MM, Burnett PE, Wolosker H, Blackshaw S, Snyder SH. Cain, a novel physiologic protein inhibitor of calcineurin. The Journal of Biological Chemistry. 273: 18325-31. PMID 9660798 DOI: 10.1074/jbc.273.29.18325  1
1998 Burnett PE, Blackshaw S, Lai MM, Qureshi IA, Burnett AF, Sabatini DM, Snyder SH. Neurabin is a synaptic protein linking p70 S6 kinase and the neuronal cytoskeleton. Proceedings of the National Academy of Sciences of the United States of America. 95: 8351-6. PMID 9653190 DOI: 10.1073/pnas.95.14.8351  1
1998 Walensky LD, Ruat M, Bakin RE, Blackshaw S, Ronnett GV, Snyder SH. Two novel odorant receptor families expressed in spermatids undergo 5'-splicing. The Journal of Biological Chemistry. 273: 9378-87. PMID 9545261 DOI: 10.1074/jbc.273.16.9378  1
1998 Walensky LD, Gascard P, Fields ME, Blackshaw S, Conboy JG, Mohandas N, Snyder SH. The 13-kD FK506 binding protein, FKBP13, interacts with a novel homologue of the erythrocyte membrane cytoskeletal protein 4.1. The Journal of Cell Biology. 141: 143-53. PMID 9531554 DOI: 10.1083/jcb.141.1.143  1
1998 Wolosker H, Kline D, Bian Y, Blackshaw S, Cameron AM, Fralich TJ, Schnaar RL, Snyder SH. Molecularly cloned mammalian glucosamine-6-phosphate deaminase localizes to transporting epithelium and lacks oscillin activity. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 12: 91-9. PMID 9438414  1
1997 Blackshaw S, Snyder SH. Parapinopsin, a novel catfish opsin localized to the parapineal organ, defines a new gene family. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 8083-92. PMID 9334384  1
1997 Blackshaw S, Snyder SH. Developmental expression pattern of phototransduction components in mammalian pineal implies a light-sensing function. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 8074-82. PMID 9334383  1
1997 O'Brien RJ, Mammen AL, Blackshaw S, Ehlers MD, Rothstein JD, Huganir RL. The development of excitatory synapses in cultured spinal neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 7339-50. PMID 9295380  1
1997 Eliasson MJ, Blackshaw S, Schell MJ, Snyder SH. Neuronal nitric oxide synthase alternatively spliced forms: prominent functional localizations in the brain. Proceedings of the National Academy of Sciences of the United States of America. 94: 3396-401. PMID 9096405 DOI: 10.1073/pnas.94.7.3396  1
1994 Li XJ, Blackshaw S, Snyder SH. Expression and localization of amiloride-sensitive sodium channel indicate a role for non-taste cells in taste perception. Proceedings of the National Academy of Sciences of the United States of America. 91: 1814-8. PMID 8127886  1
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