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Yuehai Ke, PhD - Publications

Affiliations: 
Zhejiang University School of Medicine 
Area:
Stem Cells
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43 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Song P, Xu H, He Y, Sun J, Xu Z, Huang P, Ge M, Zhang X, Ke Y, Cheng H. GAB1 is upregulated to promote anaplastic thyroid cancer cell migration through AKT-MDR1. Biochemical and Biophysical Research Communications. 607: 36-43. PMID 35366541 DOI: 10.1016/j.bbrc.2022.03.101  0.31
2021 Zhang Y, Li Y, Liu P, Gong D, Zhou H, Li W, Zhang H, Zheng W, Xu J, Cheng H, Zhang X, Ke Y. Phosphatase Shp2 regulates biogenesis of small extracellular vesicles by dephosphorylating Syntenin. Journal of Extracellular Vesicles. 10: e12078. PMID 33732417 DOI: 10.1002/jev2.12078  0.341
2020 Shi Y, Wang X, Xu Z, He Y, Guo C, He L, Huan C, Cai C, Huang J, Zhang J, Li Y, Zeng C, Zhang X, Wang L, Ke Y, et al. PDLIM5 inhibits STUB1-mediated degradation of SMAD3 and promotes the migration and invasion of lung cancer cells. The Journal of Biological Chemistry. PMID 32737199 DOI: 10.1074/Jbc.Ra120.014976  0.413
2020 Lv D, Xu Y, Cheng H, Ke Y, Zhang X, Ying K. A novel cell-based assay for dynamically detecting neutrophil extracellular traps-induced lung epithelial injuries. Experimental Cell Research. 112101. PMID 32474064 DOI: 10.1016/J.Yexcr.2020.112101  0.329
2020 Xu Y, Zhang Y, Yang Y, Liu Y, Tian Q, Liu P, Ding Z, Cheng H, Zhang X, Ke Y. Tyrosine phosphatase Shp2 regulates p115RhoGEF/Rho-dependent dendritic cell migration. Cellular & Molecular Immunology. PMID 32350404 DOI: 10.1038/S41423-020-0414-Y  0.397
2020 Huang J, Cai C, Zheng T, Wu X, Wang D, Zhang K, Xu B, Yan R, Gong H, Zhang J, Shi Y, Xu Z, Zhang X, Zhang X, Shang T, ... ... Ke Y, et al. Endothelial Scaffolding Protein ENH (Enigma Homolog Protein) Promotes PHLPP2 (Pleckstrin Homology Domain and Leucine-Rich Repeat Protein Phosphatase 2)-Mediated Dephosphorylation of AKT1 and eNOS (Endothelial NO Synthase) Promoting Vascular Remodeling. Arteriosclerosis, Thrombosis, and Vascular Biology. ATVBAHA120314172. PMID 32268790 DOI: 10.1161/Atvbaha.120.314172  0.321
2019 Gong H, Ni J, Xu Z, Huang J, Zhang J, Huang Y, Zeng C, Zhang X, Cheng H, Ke Y. Shp2 in myocytes is essential for cardiovascular and neointima development. Journal of Molecular and Cellular Cardiology. PMID 31634485 DOI: 10.1016/J.Yjmcc.2019.09.014  0.333
2019 He L, Li Y, Huang X, Cheng H, Ke Y, Wang L. The prognostic significance of SHP2 and its binding protein Hook1 in non-small cell lung cancer. Oncotargets and Therapy. 12: 5897-5906. PMID 31413587 DOI: 10.2147/Ott.S210223  0.313
2018 Ma L, Zhang X, Xu X, Ke Y, Dai J, Cheng H, Mao W. Compatibility principle in the Tanyu Tongzhi Formula revealed by a cell-based analysis. Journal of Ethnopharmacology. PMID 30508622 DOI: 10.1016/J.Jep.2018.11.043  0.381
2018 Zhang J, Huang J, Qi T, Huang Y, Lu Y, Zhan T, Gong H, Zhu Z, Shi Y, Zhou J, Yu L, Zhang X, Cheng H, Ke Y. SHP2 protects endothelial cell barrier through suppressing VE-cadherin internalization regulated by MET-ARF1. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201800284R. PMID 30102570 DOI: 10.1096/Fj.201800284R  0.355
2018 Xu C, Zou C, Hussain M, Shi W, Shao Y, Jiang Z, Wu X, Lu M, Wu J, Xie Q, Ke Y, Long F, Tang L, Wu X. High expression of Sonic hedgehog in allergic airway epithelia contributes to goblet cell metaplasia. Mucosal Immunology. PMID 29867080 DOI: 10.1038/S41385-018-0033-4  0.376
2017 Liu Y, Hu M, Luo D, Yue M, Wang S, Chen X, Zhou Y, Wang Y, Cai Y, Hu X, Ke Y, Yang Z, Hu H. Class III PI3K Positively Regulates Platelet Activation and Thrombosis via PI(3)P-Directed Function of NADPH Oxidase. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 28882875 DOI: 10.1161/Atvbaha.117.309751  0.321
2017 Xu J, Tao B, Guo X, Zhou S, Li Y, Zhang Y, Zhou Z, Cheng H, Zhang X, Ke Y. Macrophage-Restricted Shp2 Tyrosine Phosphatase Acts as a Rheostat for MMP12 through TGF-β Activation in the Prevention of Age-Related Emphysema in Mice. Journal of Immunology (Baltimore, Md. : 1950). PMID 28814604 DOI: 10.4049/Jimmunol.1601696  0.304
2017 Guo X, Li T, Xu Y, Xu X, Zhu Z, Zhang Y, Xu J, Xu K, Cheng H, Zhang X, Ke Y. Increased levels of Gab1 and Gab2 adaptor proteins skew IL-4 signaling toward M2 macrophage-driven pulmonary fibrosis in mice. The Journal of Biological Chemistry. PMID 28687632 DOI: 10.1074/Jbc.M117.802066  0.336
2017 Qiu Z, Zhou J, Liu F, Qin X, Dai Y, Ke Y, Chen Z, Li W, Ying S, Shen H. Deletion of Shp2 in bronchial epithelial cells impairs IL-25 production in vitro, but has minor influence on asthmatic inflammation in vivo. Plos One. 12: e0177334. PMID 28481957 DOI: 10.1371/Journal.Pone.0177334  0.381
2017 Fu G, Xu Q, Qiu Y, Jin X, Xu T, Dong S, Wang J, Ke Y, Hu H, Cao X, Wang D, Cantor H, Gao X, Lu L. Suppression of Th17 cell differentiation by misshapen/NIK-related kinase MINK1. The Journal of Experimental Medicine. PMID 28400474 DOI: 10.1084/Jem.20161120  0.406
2016 Zhang Y, Xu Y, Liu S, Guo X, Cen D, Xu J, Li H, Li K, Zeng C, Lu L, Zhou Y, Shen H, Cheng H, Zhang X, Ke Y. Scaffolding protein Gab1 regulates myeloid dendritic cell migration in allergic asthma. Cell Research. 26: 1226-1241. PMID 27811945 DOI: 10.1038/Cr.2016.124  0.328
2016 Wang K, Qin S, Liang Z, Zhang Y, Xu Y, Chen A, Guo X, Cheng H, Zhang X, Ke Y. Epithelial Disruption of Gab1 Perturbs Surfactant Homeostasis and Predisposes Mice to Lung Injuries. American Journal of Physiology. Lung Cellular and Molecular Physiology. ajplung.00107.2016. PMID 27793798 DOI: 10.1152/Ajplung.00107.2016  0.334
2016 Guo C, Xie S, Chi Z, Zhang J, Liu Y, Zhang L, Zheng M, Zhang X, Xia D, Ke Y, Lu L, Wang D. Bile Acids Control Inflammation and Metabolic Disorder through Inhibition of NLRP3 Inflammasome. Immunity. PMID 27692610 DOI: 10.1016/J.Immuni.2016.09.008  0.36
2016 Cao Q, Yao J, Li H, Tao B, Cai Y, Xiao P, Cheng H, Ke Y. Cellular Phenotypic Analysis of Macrophage Activation Unveils Kinetic Responses of Agents Targeting Phosphorylation. Journal of Biomolecular Screening. PMID 27554457 DOI: 10.1177/1087057116663166  0.341
2016 Qin S, Wang X, Wu H, Xiao P, Cheng H, Zhang X, Ke Y. Cell-based phenotypic screening of mast cell degranulation unveils kinetic perturbations of agents targeting phosphorylation. Scientific Reports. 6: 31320. PMID 27502076 DOI: 10.1038/Srep31320  0.395
2016 Fu H, Cheng H, Cao G, Zhang X, Tu J, Sun M, Mou X, Shou Q, Ke Y. The Inhibition of Mast Cell Activation of Radix Paeoniae alba Extraction Identified by TCRP Based and Conventional Cell Function Assay Systems. Plos One. 11: e0155930. PMID 27195739 DOI: 10.1371/Journal.Pone.0155930  0.382
2014 Wang D, Zheng M, Qiu Y, Guo C, Ji J, Lei L, Zhang X, Liang J, Lou J, Huang W, Dong B, Wu S, Wang J, Ke Y, Cao X, et al. Tespa1 negatively regulates FcεRI-mediated signaling and the mast cell-mediated allergic response. The Journal of Experimental Medicine. 211: 2635-49. PMID 25422497 DOI: 10.1084/Jem.20140470  0.451
2014 Li S, Wang L, Zhao Q, Liu Y, He L, Xu Q, Sun X, Teng L, Cheng H, Ke Y. SHP2 positively regulates TGFβ1-induced epithelial-mesenchymal transition modulated by its novel interacting protein Hook1. The Journal of Biological Chemistry. 289: 34152-60. PMID 25331952 DOI: 10.1074/Jbc.M113.546077  0.418
2014 Zhang X, Shi Y, Weng Y, Lai Q, Luo T, Zhao J, Ren G, Li W, Pan H, Ke Y, Zhang W, He Q, Wang Q, Zhou R. The truncate mutation of Notch2 enhances cell proliferation through activating the NF-κB signal pathway in the diffuse large B-cell lymphomas. Plos One. 9: e108747. PMID 25314575 DOI: 10.1371/Journal.Pone.0108747  0.378
2014 Tao B, Jin W, Xu J, Liang Z, Yao J, Zhang Y, Wang K, Cheng H, Zhang X, Ke Y. Myeloid-specific disruption of tyrosine phosphatase Shp2 promotes alternative activation of macrophages and predisposes mice to pulmonary fibrosis. Journal of Immunology (Baltimore, Md. : 1950). 193: 2801-11. PMID 25127857 DOI: 10.4049/Jimmunol.1303463  0.348
2014 Pan Y, Fu H, Kong Q, Xiao Y, Shou Q, Chen H, Ke Y, Chen M. Prevention of pulmonary fibrosis with salvianolic acid a by inducing fibroblast cell cycle arrest and promoting apoptosis. Journal of Ethnopharmacology. 155: 1589-96. PMID 25102244 DOI: 10.1016/J.Jep.2014.07.049  0.328
2014 Wang X, Zhang A, Gao J, Chen W, Wang S, Wu X, Shen Y, Ke Y, Hua Z, Tan R, Sun Y, Xu Q. Trichomide A, a natural cyclodepsipeptide, exerts immunosuppressive activity against activated T lymphocytes by upregulating SHP2 activation to overcome contact dermatitis. The Journal of Investigative Dermatology. 134: 2737-46. PMID 24933319 DOI: 10.1038/Jid.2014.252  0.382
2013 Zhang T, Guo W, Yang Y, Liu W, Guo L, Gu Y, Shu Y, Wang L, Wu X, Hua Z, Ke Y, Sun Y, Shen Y, Xu Q. Loss of SHP-2 activity in CD4+ T cells promotes melanoma progression and metastasis. Scientific Reports. 3: 2845. PMID 24088816 DOI: 10.1038/Srep02845  0.347
2013 Lin C, Guo X, Lange S, Liu J, Ouyang K, Yin X, Jiang L, Cai Y, Mu Y, Sheikh F, Ye S, Chen J, Ke Y, Cheng H. Cypher/ZASP is a novel A-kinase anchoring protein. The Journal of Biological Chemistry. 288: 29403-13. PMID 23996002 DOI: 10.1074/Jbc.M113.470708  0.31
2012 Wu X, Guo W, Wu L, Gu Y, Gu L, Xu S, Wu X, Shen Y, Ke Y, Tan R, Sun Y, Xu Q. Selective sequestration of STAT1 in the cytoplasm via phosphorylated SHP-2 ameliorates murine experimental colitis. Journal of Immunology (Baltimore, Md. : 1950). 189: 3497-507. PMID 22942432 DOI: 10.4049/Jimmunol.1201006  0.414
2012 Li FF, Shen J, Shen HJ, Zhang X, Cao R, Zhang Y, Qui Q, Lin XX, Xie YC, Zhang LH, Jia YL, Dong XW, Jiang JX, Bao MJ, Zhang S, ... ... Ke Y, et al. Shp2 plays an important role in acute cigarette smoke-mediated lung inflammation. Journal of Immunology (Baltimore, Md. : 1950). 189: 3159-67. PMID 22891281 DOI: 10.4049/Jimmunol.1200197  0.355
2012 Zhang X, Zhang Y, Tao B, Wang D, Cheng H, Wang K, Zhou R, Xie Q, Ke Y. Docking protein Gab2 regulates mucin expression and goblet cell hyperplasia through TYK2/STAT6 pathway. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 26: 4603-13. PMID 22859374 DOI: 10.1096/Fj.12-211755  0.386
2012 Zhang X, Zhang Y, Tao B, Teng L, Li Y, Cao R, Gui Q, Ye M, Mou X, Cheng H, Hu H, Zhou R, Wu X, Xie Q, Ning W, ... ... Ke Y, et al. Loss of Shp2 in alveoli epithelia induces deregulated surfactant homeostasis, resulting in spontaneous pulmonary fibrosis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 26: 2338-50. PMID 22362894 DOI: 10.1096/Fj.11-200139  0.525
2011 Futami M, Zhu QS, Whichard ZL, Xia L, Ke Y, Neel BG, Feng GS, Corey SJ. G-CSF receptor activation of the Src kinase Lyn is mediated by Gab2 recruitment of the Shp2 phosphatase. Blood. 118: 1077-86. PMID 21636860 DOI: 10.1182/Blood-2009-12-261636  0.526
2009 Hagihara K, Zhang EE, Ke YH, Liu G, Liu JJ, Rao Y, Feng GS. Shp2 acts downstream of SDF-1alpha/CXCR4 in guiding granule cell migration during cerebellar development. Developmental Biology. 334: 276-84. PMID 19635473 DOI: 10.1016/J.Ydbio.2009.07.029  0.653
2009 Wu D, Pang Y, Ke Y, Yu J, He Z, Tautz L, Mustelin T, Ding S, Huang Z, Feng GS. A conserved mechanism for control of human and mouse embryonic stem cell pluripotency and differentiation by shp2 tyrosine phosphatase. Plos One. 4: e4914. PMID 19290061 DOI: 10.1371/Journal.Pone.0004914  0.574
2009 Yu J, Zhang SS, Saito K, Williams S, Arimura Y, Ma Y, Ke Y, Baron V, Mercola D, Feng GS, Adamson E, Mustelin T. PTEN regulation by Akt-EGR1-ARF-PTEN axis. The Embo Journal. 28: 21-33. PMID 19057511 DOI: 10.1038/Emboj.2008.238  0.527
2008 Wu D, Pang Y, Ke Y, He Z, Feng G. A conserved role of Shp2 in regulation of human and mouse ES cell differentiation Cell Research. 18: S27-S27. DOI: 10.1038/Cr.2008.117  0.573
2007 Ke Y, Zhang EE, Hagihara K, Wu D, Pang Y, Klein R, Curran T, Ranscht B, Feng GS. Deletion of Shp2 in the brain leads to defective proliferation and differentiation in neural stem cells and early postnatal lethality. Molecular and Cellular Biology. 27: 6706-17. PMID 17646384 DOI: 10.1128/Mcb.01225-07  0.667
2007 Ke Y, Wu D, Princen F, Nguyen T, Pang Y, Lesperance J, Muller WJ, Oshima RG, Feng GS. Role of Gab2 in mammary tumorigenesis and metastasis. Oncogene. 26: 4951-60. PMID 17310989 DOI: 10.1038/sj.onc.1210315  0.473
2006 Nguyen TV, Ke Y, Zhang EE, Feng GS. Conditional deletion of Shp2 tyrosine phosphatase in thymocytes suppresses both pre-TCR and TCR signals. Journal of Immunology (Baltimore, Md. : 1950). 177: 5990-6. PMID 17056523 DOI: 10.4049/Jimmunol.177.9.5990  0.658
2006 Ke Y, Lesperance J, Zhang EE, Bard-Chapeau EA, Oshima RG, Muller WJ, Feng GS. Conditional deletion of Shp2 in the mammary gland leads to impaired lobulo-alveolar outgrowth and attenuated Stat5 activation. The Journal of Biological Chemistry. 281: 34374-80. PMID 16959766 DOI: 10.1074/Jbc.M607325200  0.657
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