Year |
Citation |
Score |
2022 |
Song P, Xu H, He Y, Sun J, Xu Z, Huang P, Ge M, Zhang X, Ke Y, Cheng H. GAB1 is upregulated to promote anaplastic thyroid cancer cell migration through AKT-MDR1. Biochemical and Biophysical Research Communications. 607: 36-43. PMID 35366541 DOI: 10.1016/j.bbrc.2022.03.101 |
0.31 |
|
2021 |
Zhang Y, Li Y, Liu P, Gong D, Zhou H, Li W, Zhang H, Zheng W, Xu J, Cheng H, Zhang X, Ke Y. Phosphatase Shp2 regulates biogenesis of small extracellular vesicles by dephosphorylating Syntenin. Journal of Extracellular Vesicles. 10: e12078. PMID 33732417 DOI: 10.1002/jev2.12078 |
0.34 |
|
2020 |
Shi Y, Wang X, Xu Z, He Y, Guo C, He L, Huan C, Cai C, Huang J, Zhang J, Li Y, Zeng C, Zhang X, Wang L, Ke Y, et al. PDLIM5 inhibits STUB1-mediated degradation of SMAD3 and promotes the migration and invasion of lung cancer cells. The Journal of Biological Chemistry. PMID 32737199 DOI: 10.1074/Jbc.Ra120.014976 |
0.413 |
|
2020 |
Lv D, Xu Y, Cheng H, Ke Y, Zhang X, Ying K. A novel cell-based assay for dynamically detecting neutrophil extracellular traps-induced lung epithelial injuries. Experimental Cell Research. 112101. PMID 32474064 DOI: 10.1016/J.Yexcr.2020.112101 |
0.329 |
|
2020 |
Xu Y, Zhang Y, Yang Y, Liu Y, Tian Q, Liu P, Ding Z, Cheng H, Zhang X, Ke Y. Tyrosine phosphatase Shp2 regulates p115RhoGEF/Rho-dependent dendritic cell migration. Cellular & Molecular Immunology. PMID 32350404 DOI: 10.1038/S41423-020-0414-Y |
0.397 |
|
2020 |
Huang J, Cai C, Zheng T, Wu X, Wang D, Zhang K, Xu B, Yan R, Gong H, Zhang J, Shi Y, Xu Z, Zhang X, Zhang X, Shang T, ... ... Ke Y, et al. Endothelial Scaffolding Protein ENH (Enigma Homolog Protein) Promotes PHLPP2 (Pleckstrin Homology Domain and Leucine-Rich Repeat Protein Phosphatase 2)-Mediated Dephosphorylation of AKT1 and eNOS (Endothelial NO Synthase) Promoting Vascular Remodeling. Arteriosclerosis, Thrombosis, and Vascular Biology. ATVBAHA120314172. PMID 32268790 DOI: 10.1161/Atvbaha.120.314172 |
0.321 |
|
2019 |
Gong H, Ni J, Xu Z, Huang J, Zhang J, Huang Y, Zeng C, Zhang X, Cheng H, Ke Y. Shp2 in myocytes is essential for cardiovascular and neointima development. Journal of Molecular and Cellular Cardiology. PMID 31634485 DOI: 10.1016/J.Yjmcc.2019.09.014 |
0.333 |
|
2019 |
He L, Li Y, Huang X, Cheng H, Ke Y, Wang L. The prognostic significance of SHP2 and its binding protein Hook1 in non-small cell lung cancer. Oncotargets and Therapy. 12: 5897-5906. PMID 31413587 DOI: 10.2147/Ott.S210223 |
0.313 |
|
2018 |
Ma L, Zhang X, Xu X, Ke Y, Dai J, Cheng H, Mao W. Compatibility principle in the Tanyu Tongzhi Formula revealed by a cell-based analysis. Journal of Ethnopharmacology. PMID 30508622 DOI: 10.1016/J.Jep.2018.11.043 |
0.381 |
|
2018 |
Zhang J, Huang J, Qi T, Huang Y, Lu Y, Zhan T, Gong H, Zhu Z, Shi Y, Zhou J, Yu L, Zhang X, Cheng H, Ke Y. SHP2 protects endothelial cell barrier through suppressing VE-cadherin internalization regulated by MET-ARF1. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201800284R. PMID 30102570 DOI: 10.1096/Fj.201800284R |
0.355 |
|
2018 |
Xu C, Zou C, Hussain M, Shi W, Shao Y, Jiang Z, Wu X, Lu M, Wu J, Xie Q, Ke Y, Long F, Tang L, Wu X. High expression of Sonic hedgehog in allergic airway epithelia contributes to goblet cell metaplasia. Mucosal Immunology. PMID 29867080 DOI: 10.1038/S41385-018-0033-4 |
0.376 |
|
2017 |
Liu Y, Hu M, Luo D, Yue M, Wang S, Chen X, Zhou Y, Wang Y, Cai Y, Hu X, Ke Y, Yang Z, Hu H. Class III PI3K Positively Regulates Platelet Activation and Thrombosis via PI(3)P-Directed Function of NADPH Oxidase. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 28882875 DOI: 10.1161/Atvbaha.117.309751 |
0.321 |
|
2017 |
Xu J, Tao B, Guo X, Zhou S, Li Y, Zhang Y, Zhou Z, Cheng H, Zhang X, Ke Y. Macrophage-Restricted Shp2 Tyrosine Phosphatase Acts as a Rheostat for MMP12 through TGF-β Activation in the Prevention of Age-Related Emphysema in Mice. Journal of Immunology (Baltimore, Md. : 1950). PMID 28814604 DOI: 10.4049/Jimmunol.1601696 |
0.304 |
|
2017 |
Guo X, Li T, Xu Y, Xu X, Zhu Z, Zhang Y, Xu J, Xu K, Cheng H, Zhang X, Ke Y. Increased levels of Gab1 and Gab2 adaptor proteins skew IL-4 signaling toward M2 macrophage-driven pulmonary fibrosis in mice. The Journal of Biological Chemistry. PMID 28687632 DOI: 10.1074/Jbc.M117.802066 |
0.336 |
|
2017 |
Qiu Z, Zhou J, Liu F, Qin X, Dai Y, Ke Y, Chen Z, Li W, Ying S, Shen H. Deletion of Shp2 in bronchial epithelial cells impairs IL-25 production in vitro, but has minor influence on asthmatic inflammation in vivo. Plos One. 12: e0177334. PMID 28481957 DOI: 10.1371/Journal.Pone.0177334 |
0.381 |
|
2017 |
Fu G, Xu Q, Qiu Y, Jin X, Xu T, Dong S, Wang J, Ke Y, Hu H, Cao X, Wang D, Cantor H, Gao X, Lu L. Suppression of Th17 cell differentiation by misshapen/NIK-related kinase MINK1. The Journal of Experimental Medicine. PMID 28400474 DOI: 10.1084/Jem.20161120 |
0.406 |
|
2016 |
Zhang Y, Xu Y, Liu S, Guo X, Cen D, Xu J, Li H, Li K, Zeng C, Lu L, Zhou Y, Shen H, Cheng H, Zhang X, Ke Y. Scaffolding protein Gab1 regulates myeloid dendritic cell migration in allergic asthma. Cell Research. 26: 1226-1241. PMID 27811945 DOI: 10.1038/Cr.2016.124 |
0.328 |
|
2016 |
Wang K, Qin S, Liang Z, Zhang Y, Xu Y, Chen A, Guo X, Cheng H, Zhang X, Ke Y. Epithelial Disruption of Gab1 Perturbs Surfactant Homeostasis and Predisposes Mice to Lung Injuries. American Journal of Physiology. Lung Cellular and Molecular Physiology. ajplung.00107.2016. PMID 27793798 DOI: 10.1152/Ajplung.00107.2016 |
0.334 |
|
2016 |
Guo C, Xie S, Chi Z, Zhang J, Liu Y, Zhang L, Zheng M, Zhang X, Xia D, Ke Y, Lu L, Wang D. Bile Acids Control Inflammation and Metabolic Disorder through Inhibition of NLRP3 Inflammasome. Immunity. PMID 27692610 DOI: 10.1016/J.Immuni.2016.09.008 |
0.36 |
|
2016 |
Cao Q, Yao J, Li H, Tao B, Cai Y, Xiao P, Cheng H, Ke Y. Cellular Phenotypic Analysis of Macrophage Activation Unveils Kinetic Responses of Agents Targeting Phosphorylation. Journal of Biomolecular Screening. PMID 27554457 DOI: 10.1177/1087057116663166 |
0.341 |
|
2016 |
Qin S, Wang X, Wu H, Xiao P, Cheng H, Zhang X, Ke Y. Cell-based phenotypic screening of mast cell degranulation unveils kinetic perturbations of agents targeting phosphorylation. Scientific Reports. 6: 31320. PMID 27502076 DOI: 10.1038/Srep31320 |
0.394 |
|
2016 |
Fu H, Cheng H, Cao G, Zhang X, Tu J, Sun M, Mou X, Shou Q, Ke Y. The Inhibition of Mast Cell Activation of Radix Paeoniae alba Extraction Identified by TCRP Based and Conventional Cell Function Assay Systems. Plos One. 11: e0155930. PMID 27195739 DOI: 10.1371/Journal.Pone.0155930 |
0.382 |
|
2014 |
Wang D, Zheng M, Qiu Y, Guo C, Ji J, Lei L, Zhang X, Liang J, Lou J, Huang W, Dong B, Wu S, Wang J, Ke Y, Cao X, et al. Tespa1 negatively regulates FcεRI-mediated signaling and the mast cell-mediated allergic response. The Journal of Experimental Medicine. 211: 2635-49. PMID 25422497 DOI: 10.1084/Jem.20140470 |
0.45 |
|
2014 |
Li S, Wang L, Zhao Q, Liu Y, He L, Xu Q, Sun X, Teng L, Cheng H, Ke Y. SHP2 positively regulates TGFβ1-induced epithelial-mesenchymal transition modulated by its novel interacting protein Hook1. The Journal of Biological Chemistry. 289: 34152-60. PMID 25331952 DOI: 10.1074/Jbc.M113.546077 |
0.417 |
|
2014 |
Zhang X, Shi Y, Weng Y, Lai Q, Luo T, Zhao J, Ren G, Li W, Pan H, Ke Y, Zhang W, He Q, Wang Q, Zhou R. The truncate mutation of Notch2 enhances cell proliferation through activating the NF-κB signal pathway in the diffuse large B-cell lymphomas. Plos One. 9: e108747. PMID 25314575 DOI: 10.1371/Journal.Pone.0108747 |
0.377 |
|
2014 |
Tao B, Jin W, Xu J, Liang Z, Yao J, Zhang Y, Wang K, Cheng H, Zhang X, Ke Y. Myeloid-specific disruption of tyrosine phosphatase Shp2 promotes alternative activation of macrophages and predisposes mice to pulmonary fibrosis. Journal of Immunology (Baltimore, Md. : 1950). 193: 2801-11. PMID 25127857 DOI: 10.4049/Jimmunol.1303463 |
0.348 |
|
2014 |
Pan Y, Fu H, Kong Q, Xiao Y, Shou Q, Chen H, Ke Y, Chen M. Prevention of pulmonary fibrosis with salvianolic acid a by inducing fibroblast cell cycle arrest and promoting apoptosis. Journal of Ethnopharmacology. 155: 1589-96. PMID 25102244 DOI: 10.1016/J.Jep.2014.07.049 |
0.328 |
|
2014 |
Wang X, Zhang A, Gao J, Chen W, Wang S, Wu X, Shen Y, Ke Y, Hua Z, Tan R, Sun Y, Xu Q. Trichomide A, a natural cyclodepsipeptide, exerts immunosuppressive activity against activated T lymphocytes by upregulating SHP2 activation to overcome contact dermatitis. The Journal of Investigative Dermatology. 134: 2737-46. PMID 24933319 DOI: 10.1038/Jid.2014.252 |
0.382 |
|
2013 |
Zhang T, Guo W, Yang Y, Liu W, Guo L, Gu Y, Shu Y, Wang L, Wu X, Hua Z, Ke Y, Sun Y, Shen Y, Xu Q. Loss of SHP-2 activity in CD4+ T cells promotes melanoma progression and metastasis. Scientific Reports. 3: 2845. PMID 24088816 DOI: 10.1038/Srep02845 |
0.347 |
|
2013 |
Lin C, Guo X, Lange S, Liu J, Ouyang K, Yin X, Jiang L, Cai Y, Mu Y, Sheikh F, Ye S, Chen J, Ke Y, Cheng H. Cypher/ZASP is a novel A-kinase anchoring protein. The Journal of Biological Chemistry. 288: 29403-13. PMID 23996002 DOI: 10.1074/Jbc.M113.470708 |
0.31 |
|
2012 |
Wu X, Guo W, Wu L, Gu Y, Gu L, Xu S, Wu X, Shen Y, Ke Y, Tan R, Sun Y, Xu Q. Selective sequestration of STAT1 in the cytoplasm via phosphorylated SHP-2 ameliorates murine experimental colitis. Journal of Immunology (Baltimore, Md. : 1950). 189: 3497-507. PMID 22942432 DOI: 10.4049/Jimmunol.1201006 |
0.413 |
|
2012 |
Li FF, Shen J, Shen HJ, Zhang X, Cao R, Zhang Y, Qui Q, Lin XX, Xie YC, Zhang LH, Jia YL, Dong XW, Jiang JX, Bao MJ, Zhang S, ... ... Ke Y, et al. Shp2 plays an important role in acute cigarette smoke-mediated lung inflammation. Journal of Immunology (Baltimore, Md. : 1950). 189: 3159-67. PMID 22891281 DOI: 10.4049/Jimmunol.1200197 |
0.355 |
|
2012 |
Zhang X, Zhang Y, Tao B, Wang D, Cheng H, Wang K, Zhou R, Xie Q, Ke Y. Docking protein Gab2 regulates mucin expression and goblet cell hyperplasia through TYK2/STAT6 pathway. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 26: 4603-13. PMID 22859374 DOI: 10.1096/Fj.12-211755 |
0.386 |
|
2012 |
Zhang X, Zhang Y, Tao B, Teng L, Li Y, Cao R, Gui Q, Ye M, Mou X, Cheng H, Hu H, Zhou R, Wu X, Xie Q, Ning W, ... ... Ke Y, et al. Loss of Shp2 in alveoli epithelia induces deregulated surfactant homeostasis, resulting in spontaneous pulmonary fibrosis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 26: 2338-50. PMID 22362894 DOI: 10.1096/Fj.11-200139 |
0.525 |
|
2011 |
Futami M, Zhu QS, Whichard ZL, Xia L, Ke Y, Neel BG, Feng GS, Corey SJ. G-CSF receptor activation of the Src kinase Lyn is mediated by Gab2 recruitment of the Shp2 phosphatase. Blood. 118: 1077-86. PMID 21636860 DOI: 10.1182/Blood-2009-12-261636 |
0.525 |
|
2009 |
Hagihara K, Zhang EE, Ke YH, Liu G, Liu JJ, Rao Y, Feng GS. Shp2 acts downstream of SDF-1alpha/CXCR4 in guiding granule cell migration during cerebellar development. Developmental Biology. 334: 276-84. PMID 19635473 DOI: 10.1016/J.Ydbio.2009.07.029 |
0.651 |
|
2009 |
Wu D, Pang Y, Ke Y, Yu J, He Z, Tautz L, Mustelin T, Ding S, Huang Z, Feng GS. A conserved mechanism for control of human and mouse embryonic stem cell pluripotency and differentiation by shp2 tyrosine phosphatase. Plos One. 4: e4914. PMID 19290061 DOI: 10.1371/Journal.Pone.0004914 |
0.573 |
|
2009 |
Yu J, Zhang SS, Saito K, Williams S, Arimura Y, Ma Y, Ke Y, Baron V, Mercola D, Feng GS, Adamson E, Mustelin T. PTEN regulation by Akt-EGR1-ARF-PTEN axis. The Embo Journal. 28: 21-33. PMID 19057511 DOI: 10.1038/Emboj.2008.238 |
0.526 |
|
2008 |
Wu D, Pang Y, Ke Y, He Z, Feng G. A conserved role of Shp2 in regulation of human and mouse ES cell differentiation Cell Research. 18: S27-S27. DOI: 10.1038/Cr.2008.117 |
0.572 |
|
2007 |
Ke Y, Zhang EE, Hagihara K, Wu D, Pang Y, Klein R, Curran T, Ranscht B, Feng GS. Deletion of Shp2 in the brain leads to defective proliferation and differentiation in neural stem cells and early postnatal lethality. Molecular and Cellular Biology. 27: 6706-17. PMID 17646384 DOI: 10.1128/Mcb.01225-07 |
0.666 |
|
2007 |
Ke Y, Wu D, Princen F, Nguyen T, Pang Y, Lesperance J, Muller WJ, Oshima RG, Feng GS. Role of Gab2 in mammary tumorigenesis and metastasis. Oncogene. 26: 4951-60. PMID 17310989 DOI: 10.1038/sj.onc.1210315 |
0.473 |
|
2006 |
Nguyen TV, Ke Y, Zhang EE, Feng GS. Conditional deletion of Shp2 tyrosine phosphatase in thymocytes suppresses both pre-TCR and TCR signals. Journal of Immunology (Baltimore, Md. : 1950). 177: 5990-6. PMID 17056523 DOI: 10.4049/Jimmunol.177.9.5990 |
0.657 |
|
2006 |
Ke Y, Lesperance J, Zhang EE, Bard-Chapeau EA, Oshima RG, Muller WJ, Feng GS. Conditional deletion of Shp2 in the mammary gland leads to impaired lobulo-alveolar outgrowth and attenuated Stat5 activation. The Journal of Biological Chemistry. 281: 34374-80. PMID 16959766 DOI: 10.1074/Jbc.M607325200 |
0.655 |
|
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