Rashmi Kothary, Ph.D - Publications

Affiliations: 
Ottawa Hospital Research Institute 
Area:
Muscle and nervous system integrity, pathology of neuromuscular diseases
Website:
http://www.ohri.ca/profiles/kothary.asp

137 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Smiley S, Nickerson PE, Comanita L, Daftarian N, El-Sehemy A, Tsai EL, Matan-Lithwick S, Yan K, Thurig S, Touahri Y, Dixit R, Aavani T, De Repentingy Y, Baker A, Tsilfidis C, ... ... Kothary R, et al. Establishment of a cone photoreceptor transplantation platform based on a novel cone-GFP reporter mouse line. Scientific Reports. 6: 22867. PMID 26965927 DOI: 10.1038/srep22867  0.52
2016 O'Meara RW, Cummings SE, Michalski JP, Kothary R. A new in vitro mouse oligodendrocyte precursor cell migration assay reveals a role for integrin-linked kinase in cell motility. Bmc Neuroscience. 17: 7. PMID 26831726 DOI: 10.1186/s12868-016-0242-2  0.52
2016 Lynch-Godrei A, Kothary R. Functional and Genetic Analysis of Neuronal Isoforms of BPAG1. Methods in Enzymology. 569: 355-72. PMID 26778567 DOI: 10.1016/bs.mie.2015.05.004  0.52
2015 Michalski JP, Cummings SE, O'Meara RW, Kothary R. Integrin-linked kinase regulates oligodendrocyte cytoskeleton, growth cone, and adhesion dynamics. Journal of Neurochemistry. PMID 26614167 DOI: 10.1111/jnc.13446  0.52
2015 Michalski JP, Kothary R. Oligodendrocytes in a Nutshell. Frontiers in Cellular Neuroscience. 9: 340. PMID 26388730 DOI: 10.3389/fncel.2015.00340  0.52
2015 Ferrier A, De Repentigny Y, Lynch-Godrei A, Gibeault S, Eid W, Kuo D, Zha X, Kothary R. Disruption in the autophagic process underlies the sensory neuropathy in dystonia musculorum mice. Autophagy. 11: 1025-36. PMID 26043942 DOI: 10.1080/15548627.2015.1052207  0.52
2014 McFall ER, Murray LM, Lunde JA, Jasmin BJ, Kothary R, Parks RJ. A reduction in the human adenovirus virion size through use of a shortened fibre protein does not enhance muscle transduction following systemic or localised delivery in mice. Virology. 468: 444-53. PMID 25243333 DOI: 10.1016/j.virol.2014.08.026  0.52
2014 Liu H, Yazdani A, Murray LM, Beauvais A, Kothary R. The Smn-independent beneficial effects of trichostatin A on an intermediate mouse model of spinal muscular atrophy. Plos One. 9: e101225. PMID 24984019 DOI: 10.1371/journal.pone.0101225  0.52
2014 Alvarez-Saavedra M, De Repentigny Y, Lagali PS, Raghu Ram EV, Yan K, Hashem E, Ivanochko D, Huh MS, Yang D, Mears AJ, Todd MA, Corcoran CP, Bassett EA, Tokarew NJ, Kokavec J, ... ... Kothary R, et al. Snf2h-mediated chromatin organization and histone H1 dynamics govern cerebellar morphogenesis and neural maturation. Nature Communications. 5: 4181. PMID 24946904 DOI: 10.1038/ncomms5181  0.52
2014 Hettich J, Ryan SD, de Souza ON, Saraiva Macedo Timmers LF, Tsai S, Atai NA, da Hora CC, Zhang X, Kothary R, Snapp E, Ericsson M, Grundmann K, Breakefield XO, Nery FC. Biochemical and cellular analysis of human variants of the DYT1 dystonia protein, TorsinA/TOR1A. Human Mutation. 35: 1101-13. PMID 24930953 DOI: 10.1002/humu.22602  0.52
2014 Boyer JG, Deguise MO, Murray LM, Yazdani A, De Repentigny Y, Boudreau-Larivière C, Kothary R. Myogenic program dysregulation is contributory to disease pathogenesis in spinal muscular atrophy. Human Molecular Genetics. 23: 4249-59. PMID 24691550 DOI: 10.1093/hmg/ddu142  0.52
2014 Bowerman M, Michalski JP, Beauvais A, Murray LM, DeRepentigny Y, Kothary R. Defects in pancreatic development and glucose metabolism in SMN-depleted mice independent of canonical spinal muscular atrophy neuromuscular pathology. Human Molecular Genetics. 23: 3432-44. PMID 24497575 DOI: 10.1093/hmg/ddu052  0.52
2014 Murray L, Gillingwater TH, Kothary R. Dissection of the transversus abdominis muscle for whole-mount neuromuscular junction analysis. Journal of Visualized Experiments : Jove. e51162. PMID 24457471 DOI: 10.3791/51162  0.52
2014 Ferrier A, Sato T, De Repentigny Y, Gibeault S, Bhanot K, O'Meara RW, Lynch-Godrei A, Kornfeld SF, Young KG, Kothary R. Transgenic expression of neuronal dystonin isoform 2 partially rescues the disease phenotype of the dystonia musculorum mouse model of hereditary sensory autonomic neuropathy VI. Human Molecular Genetics. 23: 2694-710. PMID 24381311 DOI: 10.1093/hmg/ddt663  0.52
2013 Boyer JG, Ferrier A, Kothary R. More than a bystander: the contributions of intrinsic skeletal muscle defects in motor neuron diseases. Frontiers in Physiology. 4: 356. PMID 24391590 DOI: 10.3389/fphys.2013.00356  0.52
2013 Boyer JG, Murray LM, Scott K, De Repentigny Y, Renaud JM, Kothary R. Early onset muscle weakness and disruption of muscle proteins in mouse models of spinal muscular atrophy. Skeletal Muscle. 3: 24. PMID 24119341 DOI: 10.1186/2044-5040-3-24  0.52
2013 Goulet BB, McFall ER, Wong CM, Kothary R, Parks RJ. Supraphysiological expression of survival motor neuron protein from an adenovirus vector does not adversely affect cell function. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 91: 252-64. PMID 23859020 DOI: 10.1139/bcb-2012-0094  0.52
2013 Liu Y, Chakroun I, Yang D, Horner E, Liang J, Aziz A, Chu A, De Repentigny Y, Dilworth FJ, Kothary R, Blais A. Six1 regulates MyoD expression in adult muscle progenitor cells. Plos One. 8: e67762. PMID 23840772 DOI: 10.1371/journal.pone.0067762  0.52
2013 Storbeck CJ, Al-Zahrani KN, Sriram R, Kawesa S, O'Reilly P, Daniel K, McKay M, Kothary R, Tsilfidis C, Sabourin LA. Distinct roles for Ste20-like kinase SLK in muscle function and regeneration. Skeletal Muscle. 3: 16. PMID 23815977 DOI: 10.1186/2044-5040-3-16  0.52
2013 O'Meara RW, Michalski JP, Anderson C, Bhanot K, Rippstein P, Kothary R. Integrin-linked kinase regulates process extension in oligodendrocytes via control of actin cytoskeletal dynamics. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 9781-93. PMID 23739974 DOI: 10.1523/JNEUROSCI.5582-12.2013  0.52
2013 Goulet BB, Kothary R, Parks RJ. At the "junction" of spinal muscular atrophy pathogenesis: the role of neuromuscular junction dysfunction in SMA disease progression. Current Molecular Medicine. 13: 1160-74. PMID 23514457 DOI: 10.2174/15665240113139990044  0.52
2013 Ferrier A, Boyer JG, Kothary R. Cellular and molecular biology of neuronal dystonin. International Review of Cell and Molecular Biology. 300: 85-120. PMID 23273860 DOI: 10.1016/B978-0-12-405210-9.00003-5  0.52
2013 Sanchez G, Dury AY, Murray LM, Biondi O, Tadesse H, El Fatimy R, Kothary R, Charbonnier F, Khandjian EW, Côté J. A novel function for the survival motoneuron protein as a translational regulator. Human Molecular Genetics. 22: 668-84. PMID 23136128 DOI: 10.1093/hmg/dds474  0.52
2013 Murray LM, Beauvais A, Bhanot K, Kothary R. Defects in neuromuscular junction remodelling in the Smn(2B/-) mouse model of spinal muscular atrophy. Neurobiology of Disease. 49: 57-67. PMID 22960106 DOI: 10.1016/j.nbd.2012.08.019  0.52
2012 Bowerman M, Swoboda KJ, Michalski JP, Wang GS, Reeks C, Beauvais A, Murphy K, Woulfe J, Screaton RA, Scott FW, Kothary R. Glucose metabolism and pancreatic defects in spinal muscular atrophy. Annals of Neurology. 72: 256-68. PMID 22926856 DOI: 10.1002/ana.23582  0.52
2012 Ryan SD, Ferrier A, Kothary R. A novel role for the cytoskeletal linker protein dystonin in the maintenance of microtubule stability and the regulation of ER-Golgi transport. Bioarchitecture. 2: 2-5. PMID 22754620  0.6
2012 Ghanem N, Andrusiak MG, Svoboda D, Al Lafi SM, Julian LM, McClellan KA, De Repentigny Y, Kothary R, Ekker M, Blais A, Park DS, Slack RS. The Rb/E2F pathway modulates neurogenesis through direct regulation of the Dlx1/Dlx2 bigene cluster. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 8219-30. PMID 22699903 DOI: 10.1523/JNEUROSCI.1344-12.2012  0.52
2012 Atai NA, Ryan SD, Kothary R, Breakefield XO, Nery FC. Untethering the nuclear envelope and cytoskeleton: biologically distinct dystonias arising from a common cellular dysfunction. International Journal of Cell Biology. 2012: 634214. PMID 22611399 DOI: 10.1155/2012/634214  0.52
2012 Ryan SD, Bhanot K, Ferrier A, De Repentigny Y, Chu A, Blais A, Kothary R. Microtubule stability, Golgi organization, and transport flux require dystonin-a2-MAP1B interaction. The Journal of Cell Biology. 196: 727-42. PMID 22412020 DOI: 10.1083/jcb.201107096  0.52
2012 Bowerman M, Murray LM, Boyer JG, Anderson CL, Kothary R. Fasudil improves survival and promotes skeletal muscle development in a mouse model of spinal muscular atrophy. Bmc Medicine. 10: 24. PMID 22397316 DOI: 10.1186/1741-7015-10-24  0.52
2012 Knight JD, Tian R, Lee RE, Wang F, Beauvais A, Zou H, Megeney LA, Gingras AC, Pawson T, Figeys D, Kothary R. A novel whole-cell lysate kinase assay identifies substrates of the p38 MAPK in differentiating myoblasts. Skeletal Muscle. 2: 5. PMID 22394512 DOI: 10.1186/2044-5040-2-5  0.52
2012 Ryan SD, Ferrier A, Sato T, O'Meara RW, De Repentigny Y, Jiang SX, Hou ST, Kothary R. Neuronal dystonin isoform 2 is a mediator of endoplasmic reticulum structure and function. Molecular Biology of the Cell. 23: 553-66. PMID 22190742 DOI: 10.1091/mbc.E11-06-0573  0.52
2012 Bowerman M, Murray LM, Beauvais A, Pinheiro B, Kothary R. A critical smn threshold in mice dictates onset of an intermediate spinal muscular atrophy phenotype associated with a distinct neuromuscular junction pathology. Neuromuscular Disorders : Nmd. 22: 263-76. PMID 22071333 DOI: 10.1016/j.nmd.2011.09.007  0.52
2011 Poulin KL, Tong G, Vorobyova O, Pool M, Kothary R, Parks RJ. Use of Cre/loxP recombination to swap cell binding motifs on the adenoviral capsid protein IX. Virology. 420: 146-55. PMID 21968200 DOI: 10.1016/j.virol.2011.09.004  0.52
2011 Bhanot K, Young KG, Kothary R. MAP1B and clathrin are novel interacting partners of the giant cyto-linker dystonin. Journal of Proteome Research. 10: 5118-27. PMID 21936565 DOI: 10.1021/pr200564g  0.52
2011 Knight JD, Kothary R. The myogenic kinome: protein kinases critical to mammalian skeletal myogenesis. Skeletal Muscle. 1: 29. PMID 21902831 DOI: 10.1186/2044-5040-1-29  0.52
2011 O'Meara RW, Ryan SD, Colognato H, Kothary R. Derivation of enriched oligodendrocyte cultures and oligodendrocyte/neuron myelinating co-cultures from post-natal murine tissues. Journal of Visualized Experiments : Jove. PMID 21876528 DOI: 10.3791/3324  0.52
2011 De Repentigny Y, Ferrier A, Ryan SD, Sato T, Kothary R. Motor unit abnormalities in Dystonia musculorum mice. Plos One. 6: e21093. PMID 21698255 DOI: 10.1371/journal.pone.0021093  0.52
2011 Michalski JP, Anderson C, Beauvais A, De Repentigny Y, Kothary R. The proteolipid protein promoter drives expression outside of the oligodendrocyte lineage during embryonic and early postnatal development. Plos One. 6: e19772. PMID 21572962 DOI: 10.1371/journal.pone.0019772  0.52
2011 Fukuda K, Knight JD, Piszczek G, Kothary R, Qin J. Biochemical, proteomic, structural, and thermodynamic characterizations of integrin-linked kinase (ILK): cross-validation of the pseudokinase. The Journal of Biological Chemistry. 286: 21886-95. PMID 21524996 DOI: 10.1074/jbc.M111.240093  0.52
2011 Abdul-Ghani M, Dufort D, Stiles R, De Repentigny Y, Kothary R, Megeney LA. Wnt11 promotes cardiomyocyte development by caspase-mediated suppression of canonical Wnt signals. Molecular and Cellular Biology. 31: 163-78. PMID 21041481 DOI: 10.1128/MCB.01539-09  0.52
2011 Liu H, Beauvais A, Baker AN, Tsilfidis C, Kothary R. Smn deficiency causes neuritogenesis and neurogenesis defects in the retinal neurons of a mouse model of spinal muscular atrophy. Developmental Neurobiology. 71: 153-69. PMID 20862739 DOI: 10.1002/dneu.20840  0.52
2010 Hammond SM, Gogliotti RG, Rao V, Beauvais A, Kothary R, DiDonato CJ. Mouse survival motor neuron alleles that mimic SMN2 splicing and are inducible rescue embryonic lethality early in development but not late. Plos One. 5: e15887. PMID 21249120 DOI: 10.1371/journal.pone.0015887  0.52
2010 Poulin KL, Lanthier RM, Smith AC, Christou C, Risco Quiroz M, Powell KL, O'Meara RW, Kothary R, Lorimer IA, Parks RJ. Retargeting of adenovirus vectors through genetic fusion of a single-chain or single-domain antibody to capsid protein IX. Journal of Virology. 84: 10074-86. PMID 20631131 DOI: 10.1128/JVI.02665-09  0.52
2010 Boyer JG, Bhanot K, Kothary R, Boudreau-Larivière C. Hearts of dystonia musculorum mice display normal morphological and histological features but show signs of cardiac stress. Plos One. 5: e9465. PMID 20209123 DOI: 10.1371/journal.pone.0009465  0.52
2010 Shafey D, Boyer JG, Bhanot K, Kothary R. Identification of novel interacting protein partners of SMN using tandem affinity purification. Journal of Proteome Research. 9: 1659-69. PMID 20201562 DOI: 10.1021/pr9006987  0.52
2010 De Repentigny Y, Kothary R. Production of mouse chimeras by injection of embryonic stem cells into the perivitelline space of one-cell stage embryos. Transgenic Research. 19: 1137-44. PMID 20143261 DOI: 10.1007/s11248-010-9369-6  0.52
2010 Bowerman M, Beauvais A, Anderson CL, Kothary R. Rho-kinase inactivation prolongs survival of an intermediate SMA mouse model. Human Molecular Genetics. 19: 1468-78. PMID 20097679 DOI: 10.1093/hmg/ddq021  0.52
2010 Miura P, Coriati A, Bélanger G, De Repentigny Y, Lee J, Kothary R, Holcik M, Jasmin BJ. The utrophin A 5'-UTR drives cap-independent translation exclusively in skeletal muscles of transgenic mice and interacts with eEF1A2. Human Molecular Genetics. 19: 1211-20. PMID 20053670 DOI: 10.1093/hmg/ddp591  0.52
2010 Liu H, Shafey D, Moores JN, Kothary R. Neurodevelopmental consequences of Smn depletion in a mouse model of spinal muscular atrophy. Journal of Neuroscience Research. 88: 111-22. PMID 19642194 DOI: 10.1002/jnr.22189  0.52
2010 Michaud JL, Stitt-Cavanaugh E, Endlich N, Endlich K, De Repentigny Y, Kothary R, Kennedy CR. Mice with podocyte-specific overexpression of wild type alpha-actinin-4 are healthy controls for K256E-alpha-actinin-4 mutant transgenic mice. Transgenic Research. 19: 285-9. PMID 19585264 DOI: 10.1007/s11248-009-9305-9  0.52
2010 Boyer JG, Bowerman M, Kothary R. The many faces of SMN: Deciphering the function critical to spinal muscular atrophy pathogenesis Future Neurology. 5: 873-890. DOI: 10.2217/fnl.10.57  0.52
2009 Savory JG, Bouchard N, Pierre V, Rijli FM, De Repentigny Y, Kothary R, Lohnes D. Cdx2 regulation of posterior development through non-Hox targets. Development (Cambridge, England). 136: 4099-110. PMID 19906845 DOI: 10.1242/dev.041582  0.52
2009 Fernando P, Sandoz JS, Ding W, de Repentigny Y, Brunette S, Kelly JF, Kothary R, Megeney LA. Bin1 SRC homology 3 domain acts as a scaffold for myofiber sarcomere assembly. The Journal of Biological Chemistry. 284: 27674-86. PMID 19633357 DOI: 10.1074/jbc.M109.029538  0.52
2009 Bowerman M, Anderson CL, Beauvais A, Boyl PP, Witke W, Kothary R. SMN, profilin IIa and plastin 3: a link between the deregulation of actin dynamics and SMA pathogenesis. Molecular and Cellular Neurosciences. 42: 66-74. PMID 19497369 DOI: 10.1016/j.mcn.2009.05.009  0.52
2009 Knight JD, Hamelberg D, McCammon JA, Kothary R. The role of conserved water molecules in the catalytic domain of protein kinases. Proteins. 76: 527-35. PMID 19425109 DOI: 10.1002/prot.22451  0.52
2008 Young KG, Kothary R. Dystonin/Bpag1 is a necessary endoplasmic reticulum/nuclear envelope protein in sensory neurons. Experimental Cell Research. 314: 2750-61. PMID 18638474 DOI: 10.1016/j.yexcr.2008.06.021  0.52
2008 Ichikawa H, Terayama R, Yamaai T, De Repentigny Y, Kothary R, Sugimoto T. The number of nociceptors in the trigeminal ganglion but not proprioceptors in the mesencephalic trigeminal tract nucleus is reduced in dystonin deficient dystonia musculorum mice. Brain Research. 1226: 33-8. PMID 18619576 DOI: 10.1016/j.brainres.2008.05.063  0.52
2008 Mattis VB, Bowerman M, Kothary R, Lorson CL. A SMNDelta7 read-through product confers functionality to the SMNDelta7 protein. Neuroscience Letters. 442: 54-8. PMID 18601974 DOI: 10.1016/j.neulet.2008.06.059  0.52
2008 Shafey D, MacKenzie AE, Kothary R. Neurodevelopmental abnormalities in neurosphere-derived neural stem cells from SMN-depleted mice. Journal of Neuroscience Research. 86: 2839-47. PMID 18521935 DOI: 10.1002/jnr.21743  0.52
2007 Knight JD, Qian B, Baker D, Kothary R. Conservation, variability and the modeling of active protein kinases. Plos One. 2: e982. PMID 17912359 DOI: 10.1371/journal.pone.0000982  0.52
2007 Bowerman M, Shafey D, Kothary R. Smn depletion alters profilin II expression and leads to upregulation of the RhoA/ROCK pathway and defects in neuronal integrity. Journal of Molecular Neuroscience : Mn. 32: 120-31. PMID 17873296 DOI: 10.1007/s12031-007-0024-5  0.52
2007 Young KG, Kothary R. Dystonin/Bpag1--a link to what? Cell Motility and the Cytoskeleton. 64: 897-905. PMID 17849487 DOI: 10.1002/cm.20235  0.52
2007 Young KG, De Repentigny Y, Kothary R. Re: "A possible cellular mechanism of neuronal loss in the dorsal root ganglia of dystonia musculorum (dt) mice". Journal of Neuropathology and Experimental Neurology. 66: 248-9; author reply . PMID 17356386 DOI: 10.1097/01.jnen.0000248560.60703.45  0.52
2007 Ichikawa H, Terayama R, Yamaai T, De Repentigny Y, Kothary R, Sugimoto T. Dystonin deficiency reduces taste buds and fungiform papillae in the anterior part of the tongue. Brain Research. 1129: 142-6. PMID 17156752 DOI: 10.1016/j.brainres.2006.04.044  0.52
2006 Karamboulas C, Dakubo GD, Liu J, De Repentigny Y, Yutzey K, Wallace VA, Kothary R, Skerjanc IS. Disruption of MEF2 activity in cardiomyoblasts inhibits cardiomyogenesis. Journal of Cell Science. 119: 4315-21. PMID 17003108 DOI: 10.1242/jcs.03186  0.52
2006 Anderson CL, De Repentigny Y, Cifelli C, Marshall P, Renaud JM, Worton RG, Kothary R. The mouse dystrophin muscle promoter/enhancer drives expression of mini-dystrophin in transgenic mdx mice and rescues the dystrophy in these mice. Molecular Therapy : the Journal of the American Society of Gene Therapy. 14: 724-34. PMID 16807118 DOI: 10.1016/j.ymthe.2006.04.013  0.52
2006 Lee KK, de Repentigny Y, Saulnier R, Rippstein P, Macklin WB, Kothary R. Dominant-negative beta1 integrin mice have region-specific myelin defects accompanied by alterations in MAPK activity. Glia. 53: 836-44. PMID 16575886 DOI: 10.1002/glia.20343  0.52
2006 Pool M, Rippstein P, McBride H, Kothary R. Trafficking of macromolecules and organelles in cultured Dystonia musculorum sensory neurons is normal. The Journal of Comparative Neurology. 494: 549-58. PMID 16374799 DOI: 10.1002/cne.20815  0.52
2006 Ichikawa H, De Repentigny Y, Kothary R, Sugimoto T. The survival of vagal and glossopharyngeal sensory neurons is dependent upon dystonin. Neuroscience. 137: 531-6. PMID 16289886 DOI: 10.1016/j.neuroscience.2005.08.081  0.52
2006 Young KG, Pinheiro B, Kothary R. A Bpag1 isoform involved in cytoskeletal organization surrounding the nucleus. Experimental Cell Research. 312: 121-34. PMID 16289082 DOI: 10.1016/j.yexcr.2005.10.002  0.52
2005 Pool M, Boudreau Larivière C, Bernier G, Young KG, Kothary R. Genetic alterations at the Bpag1 locus in dt mice and their impact on transcript expression. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 16: 909-17. PMID 16341670 DOI: 10.1007/s00335-005-0073-4  0.52
2005 Shafey D, Côté PD, Kothary R. Hypomorphic Smn knockdown C2C12 myoblasts reveal intrinsic defects in myoblast fusion and myotube morphology. Experimental Cell Research. 311: 49-61. PMID 16219305 DOI: 10.1016/j.yexcr.2005.08.019  0.52
2005 Davies KE. Regulation of utrophin in transgenic mice. Neuromuscular Disorders : Nmd. 15: 648; author reply 64. PMID 16081285 DOI: 10.1016/j.nmd.2005.06.013  0.52
2005 Naas T, Ghorbani M, Alvarez-Maya I, Lapner M, Kothary R, De Repentigny Y, Gomes S, Babiuk L, Giulivi A, Soare C, Azizi A, Diaz-Mitoma F. Characterization of liver histopathology in a transgenic mouse model expressing genotype 1a hepatitis C virus core and envelope proteins 1 and 2. The Journal of General Virology. 86: 2185-96. PMID 16033966 DOI: 10.1099/vir.0.80969-0  0.52
2005 Stocksley MA, Chakkalakal JV, Bradford A, Miura P, De Repentigny Y, Kothary R, Jasmin BJ. A 1.3 kb promoter fragment confers spatial and temporal expression of utrophin A mRNA in mouse skeletal muscle fibers. Neuromuscular Disorders : Nmd. 15: 437-49. PMID 15907291 DOI: 10.1016/j.nmd.2005.03.008  0.52
2005 Côté PD, De Repentigny Y, Coupland SG, Schwab Y, Roux MJ, Levinson SR, Kothary R. Physiological maturation of photoreceptors depends on the voltage-gated sodium channel NaV1.6 (Scn8a). The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 5046-50. PMID 15901786 DOI: 10.1523/JNEUROSCI.4692-04.2005  0.52
2005 Fernando P, Deng W, Pekalska B, DeRepentigny Y, Kothary R, Kelly JF, Megeney LA. Active kinase proteome screening reveals novel signal complexity in cardiomyopathy. Molecular & Cellular Proteomics : McP. 4: 673-82. PMID 15722372 DOI: 10.1074/mcp.M400200-MCP200  0.52
2005 Young KG, Kothary R. Spectrin repeat proteins in the nucleus. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 27: 144-52. PMID 15666356 DOI: 10.1002/bies.20177  0.52
2005 Horsford DJ, Nguyen MT, Sellar GC, Kothary R, Arnheiter H, McInnes RR. Chx10 repression of Mitf is required for the maintenance of mammalian neuroretinal identity. Development (Cambridge, England). 132: 177-87. PMID 15576400 DOI: 10.1242/dev.01571  0.52
2004 De Repentigny Y, Marshall P, Worton RG, Kothary R. The mouse dystrophin muscle enhancer-1 imparts skeletal muscle, but not cardiac muscle, expression onto the dystrophin Purkinje promoter in transgenic mice. Human Molecular Genetics. 13: 2853-62. PMID 15385445 DOI: 10.1093/hmg/ddh305  0.52
2003 Young KG, Pool M, Kothary R. Bpag1 localization to actin filaments and to the nucleus is regulated by its N-terminus. Journal of Cell Science. 116: 4543-55. PMID 14576348 DOI: 10.1242/jcs.00764  0.52
2003 De Repentigny Y, Deschênes-Furry J, Jasmin BJ, Kothary R. Impaired fast axonal transport in neurons of the sciatic nerves from dystonia musculorum mice. Journal of Neurochemistry. 86: 564-71. PMID 12859670 DOI: 10.1046/j.1471-4159.2003.01861.x  0.52
2003 DiDonato CJ, Parks RJ, Kothary R. Development of a gene therapy strategy for the restoration of survival motor neuron protein expression: implications for spinal muscular atrophy therapy. Human Gene Therapy. 14: 179-88. PMID 12614569 DOI: 10.1089/104303403321070874  0.52
2003 Lee SH, Zafer A, de Repentigny Y, Kothary R, Tremblay ML, Gros P, Duplay P, Webb JR, Vidal SM. Transgenic expression of the activating natural killer receptor Ly49H confers resistance to cytomegalovirus in genetically susceptible mice. The Journal of Experimental Medicine. 197: 515-26. PMID 12591908 DOI: 10.1084/jem.20021713  0.52
2002 Boudreau-Larivière C, Kothary R. Differentiation potential of primary myogenic cells derived from skeletal muscle of dystonia musculorum mice. Differentiation; Research in Biological Diversity. 70: 247-56. PMID 12190986 DOI: 10.1046/j.1432-0436.2002.700603.x  0.52
2002 Campsall KD, Mazerolle CJ, De Repentingy Y, Kothary R, Wallace VA. Characterization of transgene expression and Cre recombinase activity in a panel of Thy-1 promoter-Cre transgenic mice. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 224: 135-43. PMID 12112467 DOI: 10.1002/dvdy.10092  0.52
2002 Saulnier R, De Repentigny Y, Yong VW, Kothary R. Alterations in myelination in the central nervous system of dystonia musculorum mice. Journal of Neuroscience Research. 69: 233-42. PMID 12111805 DOI: 10.1002/jnr.10289  0.52
2002 Marshall P, Chartrand N, De Repentigny Y, Kothary R, Pelletier L, Mueller R, Worton RG. Mouse dystrophin enhancer preferentially targets lacZ expression in skeletal and cardiac muscle. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 224: 30-8. PMID 11984871 DOI: 10.1002/dvdy.10080  0.52
2002 Young PJ, DiDonato CJ, Hu D, Kothary R, Androphy EJ, Lorson CL. SRp30c-dependent stimulation of survival motor neuron (SMN) exon 7 inclusion is facilitated by a direct interaction with hTra2 beta 1. Human Molecular Genetics. 11: 577-87. PMID 11875052  0.52
2002 Bérubé NG, Jagla M, Smeenk C, De Repentigny Y, Kothary R, Picketts DJ. Neurodevelopmental defects resulting from ATRX overexpression in transgenic mice. Human Molecular Genetics. 11: 253-61. PMID 11823444  0.52
2001 DiDonato CJ, Lorson CL, De Repentigny Y, Simard L, Chartrand C, Androphy EJ, Kothary R. Regulation of murine survival motor neuron (Smn) protein levels by modifying Smn exon 7 splicing. Human Molecular Genetics. 10: 2727-36. PMID 11726560  0.52
2001 De Repentigny Y, Côté PD, Pool M, Bernier G, Girard S, Vidal SM, Kothary R. Pathological and genetic analysis of the degenerating muscle (dmu) mouse: a new allele of Scn8a. Human Molecular Genetics. 10: 1819-27. PMID 11532991  0.52
2001 Dagenais A, Denis C, Vives MF, Girouard S, Massé C, Nguyen T, Yamagata T, Grygorczyk C, Kothary R, Berthiaume Y. Modulation of alpha-ENaC and alpha1-Na+-K+-ATPase by cAMP and dexamethasone in alveolar epithelial cells. American Journal of Physiology. Lung Cellular and Molecular Physiology. 281: L217-30. PMID 11404265  0.52
2001 Carlsten JA, Kothary R, Wright DE. Glial cell line-derived neurotrophic factor-responsive and neurotrophin-3-responsive neurons require the cytoskeletal linker protein dystonin for postnatal survival. The Journal of Comparative Neurology. 432: 155-68. PMID 11241383 DOI: 10.1002/cne.1094  0.52
2000 Mei Q, Kothary R, Wall L. The tkNeo gene, but not the pgkPuro gene, can influence the ability of the beta-globin LCR to enhance and confer position-independent expression onto the beta-globin gene. Experimental Cell Research. 260: 304-12. PMID 11035925 DOI: 10.1006/excr.2000.5030  0.52
2000 Bernier G, Pool M, Kilcup M, Alfoldi J, De Repentigny Y, Kothary R. Acf7 (MACF) is an actin and microtubule linker protein whose expression predominates in neural, muscle, and lung development. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 219: 216-25. PMID 11002341 DOI: 10.1002/1097-0177(2000)9999:9999<::AID-DVDY1041>3.0.CO;2-O  0.52
2000 Mainguy G, Montesinos ML, Lesaffre B, Zevnik B, Karasawa M, Kothary R, Wurst W, Prochiantz A, Volovitch M. An induction gene trap for identifying a homeoprotein-regulated locus. Nature Biotechnology. 18: 746-9. PMID 10888842 DOI: 10.1038/77312  0.52
1999 Kolodziejczyk SM, Wang L, Balazsi K, DeRepentigny Y, Kothary R, Megeney LA. MEF2 is upregulated during cardiac hypertrophy and is required for normal post-natal growth of the myocardium. Current Biology : Cb. 9: 1203-6. PMID 10531040 DOI: 10.1016/S0960-9822(00)80027-5  0.52
1999 Dalpé G, Mathieu M, Comtois A, Zhu E, Wasiak S, De Repentigny Y, Leclerc N, Kothary R. Dystonin-deficient mice exhibit an intrinsic muscle weakness and an instability of skeletal muscle cytoarchitecture. Developmental Biology. 210: 367-80. PMID 10357897 DOI: 10.1006/dbio.1999.9263  0.52
1998 Krause R, Hemberger M, Messerschmid M, Mayer W, Kothary R, Dixkens C, Fundele R. Molecular cloning and characterization of murine Mpgc60, a gene predominantly expressed in the intestinal tract. Differentiation; Research in Biological Diversity. 63: 285-94. PMID 9810707 DOI: 10.1046/j.1432-0436.1998.6350285.x  0.52
1998 Dalpé G, Leclerc N, Vallée A, Messer A, Mathieu M, De Repentigny Y, Kothary R. Dystonin Is Essential for Maintaining Neuronal Cytoskeleton Organization. Molecular and Cellular Neurosciences. 10: 243-57. PMID 9618216 DOI: 10.1006/mcne.1997.0660  0.52
1998 Bernier G, Kothary R. Prenatal onset of axonopathy in Dystonia musculorum mice. Developmental Genetics. 22: 160-8. PMID 9581287 DOI: 10.1002/(SICI)1520-6408(1998)22:2<160::AID-DVG5>3.0.CO;2-4  0.52
1998 Bernier G, De Repentigny Y, Mathieu M, David S, Kothary R. Dystonin is an essential component of the Schwann cell cytoskeleton at the time of myelination. Development (Cambridge, England). 125: 2135-48. PMID 9570777  0.52
1997 Guy LG, Kothary R, Wall L. Position effects in mice carrying a lacZ transgene in cis with the beta-globin LCR can be explained by a graded model. Nucleic Acids Research. 25: 4400-7. PMID 9336475 DOI: 10.1093/nar/25.21.4400  0.52
1997 Dagenais A, Kothary R, Berthiaume Y. The alpha subunit of the epithelial sodium channel in the mouse: developmental regulation of its expression. Pediatric Research. 42: 327-34. PMID 9284273 DOI: 10.1203/00006450-199709000-00013  0.52
1996 Bernier G, Mathieu M, De Repentigny Y, Vidal SM, Kothary R. Cloning and characterization of mouse ACF7, a novel member of the dystonin subfamily of actin binding proteins. Genomics. 38: 19-29. PMID 8954775 DOI: 10.1006/geno.1996.0587  0.52
1996 Bérard J, Laboune F, Mukuna M, Massé S, Kothary R, Bradley WE. Lung tumors in mice expressing an antisense RARbeta2 transgene. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 10: 1091-7. PMID 8801172  0.52
1996 Guy LG, Kothary R, DeRepentigny Y, Delvoye N, Ellis J, Wall L. The beta-globin locus control region enhances transcription of but does not confer position-independent expression onto the lacZ gene in transgenic mice. The Embo Journal. 15: 3713-21. PMID 8670875  0.52
1995 Bernier G, Brown A, Dalpé G, De Repentigny Y, Mathieu M, Kothary R. Dystonin expression in the developing nervous system predominates in the neurons that degenerate in dystonia musculorum mutant mice. Molecular and Cellular Neurosciences. 6: 509-20. PMID 8742268 DOI: 10.1006/mcne.1995.0003  0.52
1995 Bernier G, Brown A, Dalpé G, Mathieu M, De Repentigny Y, Kothary R. Dystonin transcripts are altered and their levels are reduced in the mouse neurological mutant dt24J Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 73: 605-609. PMID 8714679  0.52
1995 Brown A, Dalpé G, Mathieu M, Kothary R. Cloning and characterization of the neural isoforms of human dystonin. Genomics. 29: 777-80. PMID 8575775 DOI: 10.1006/geno.1995.9936  0.52
1995 Brown A, Bernier G, Mathieu M, Rossant J, Kothary R. The mouse dystonia musculorum gene is a neural isoform of bullous pemphigoid antigen 1. Nature Genetics. 10: 301-6. PMID 7670468 DOI: 10.1038/ng0795-301  0.52
1995 Sévigny G, Kothary R, Tremblay E, De Repentigny Y, Joly EC, Bibor-Hardy V. The cytosolic chaperonin subunit TRiC-P5 begins to be expressed at the two-cell stage in mouse embryos. Biochemical and Biophysical Research Communications. 216: 279-83. PMID 7488101 DOI: 10.1006/bbrc.1995.2621  0.52
1995 Bender R, Fundele R, Surani MA, Li LL, Kothary R, Fürst DO, Christ B. Tissue specific loss of proliferative capacity of parthenogenetic cells in fetal mouse chimeras Roux's Archives of Developmental Biology. 204: 436-443. DOI: 10.1007/BF00360851  0.52
1994 Brown A, Copeland NG, Gilbert DJ, Jenkins NA, Rossant J, Kothary R. The genomic structure of an insertional mutation in the dystonia musculorum locus. Genomics. 20: 371-6. PMID 8034309 DOI: 10.1006/geno.1994.1190  0.52
1994 Bérard J, Gaboury L, Landers M, De Repentigny Y, Houle B, Kothary R, Bradley WE. Hyperplasia and tumours in lung, breast and other tissues in mice carrying a RAR beta 4-like transgene. The Embo Journal. 13: 5570-80. PMID 7988554  0.52
1994 Brown A, Lemieux N, Rossant J, Kothary R. Human homolog of a mouse sequence from the dystonia musculorum locus is on chromosome 6p12. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 5: 434-7. PMID 7919656 DOI: 10.1007/BF00357004  0.52
1993 Franz T, Kothary R. Characterization of the neural crest defect in Splotch (Sp1H) mutant mice using a lacZ transgene. Brain Research. Developmental Brain Research. 72: 99-105. PMID 8453768 DOI: 10.1016/0165-3806(93)90163-5  0.52
1993 Franz T, Kothary R, Surani MA, Halata Z, Grim M. The Splotch mutation interferes with muscle development in the limbs. Anatomy and Embryology. 187: 153-60. PMID 8238963 DOI: 10.1007/BF00171747  0.52
1992 Jägerbauer EM, Fraser A, Herbst EW, Kothary R, Fundele R. Parthenogenetic stem cells in postnatal mouse chimeras. Development (Cambridge, England). 116: 95-102. PMID 1483398  0.52
1992 Kothary RK, Allen ND, Barton SC, Norris ML, Surani MA. Factors affecting cellular mosaicism in the expression of a lacZ transgene in two-cell stage mouse embryos Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 70: 1097-1104. PMID 1297334  0.52
1991 Fundele R, Howlett SK, Kothary R, Norris ML, Mills WE, Surani MA. Developmental potential of parthenogenetic cells: Role of genotype-specific modifiers Development. 113: 941-946. PMID 1821861  0.52
1991 Singh PB, Miller JR, Pearce J, Kothary R, Burton RD, Paro R, James TC, Gaunt SJ. A sequence motif found in a Drosophila heterochromatin protein is conserved in animals and plants. Nucleic Acids Research. 19: 789-94. PMID 1708124  0.52
1991 Kothary R, Barton SC, Franz T, Norris ML, Hettle S, Surani MA. Unusual cell specific expression of a major human cytomegalovirus immediate early gene promoter-lacZ hybrid gene in transgenic mouse embryos. Mechanisms of Development. 35: 25-31. PMID 1659441 DOI: 10.1016/0925-4773(91)90038-8  0.52
1990 Surani MA, Kothary R, Allen ND, Singh PB, Fundele R, Ferguson-Smith AC, Barton SC. Genome imprinting and development in the mouse Development (Cambridge, England). Supplement. 89-98. PMID 2090435  0.52
1989 Kothary RK, Allen ND, Surani MA. Transgenes as molecular probes of mammalian developmental genetics Oxford Surveys On Eukaryotic Genes. 6: 145-178. PMID 2698630  0.52
1989 Kothary R, Clapoff S, Darling S, Perry MD, Moran LA, Rossant J. Inducible expression of an hsp68-lacZ hybrid gene in transgenic mice. Development (Cambridge, England). 105: 707-14. PMID 2557196  0.52
1988 Varmuza S, Prideaux V, Kothary R, Rossant J. Polytene chromosomes in mouse trophoblast giant cells. Development (Cambridge, England). 102: 127-34. PMID 3166422  0.52
1988 Kothary R, Clapoff S, Brown A, Campbell R, Peterson A, Rossant J. A transgene containing lacZ inserted into the dystonia locus is expressed in neural tube. Nature. 335: 435-7. PMID 3138544 DOI: 10.1038/335435a0  0.52
1987 Kothary R, Perry MD, Moran LA, Rossant J. Cell-lineage-specific expression of the mouse hsp68 gene during embryogenesis. Developmental Biology. 121: 342-8. PMID 3582732 DOI: 10.1016/0012-1606(87)90170-9  0.52
1985 Kothary RK, Jones D, Candido EPM. IS186: An Escherichia coli insertion element isolated from a cDNA library Journal of Bacteriology. 164: 957-959. PMID 2997142  0.52
1985 Huszar D, Balling R, Kothary R, Magli MC, Hozumi N, Rossant J, Bernstein A. Insertion of a bacterial gene into the mouse germ line using an infectious retrovirus vector. Proceedings of the National Academy of Sciences of the United States of America. 82: 8587-91. PMID 2417225  0.52
1984 Burgess EA, Kothary RK, Candido EPM. Inducibility of heat shock polypeptides in cells containing hyperacetylated histones Experimental Cell Research. 155: 273-277. PMID 6489461 DOI: 10.1016/0014-4827(84)90789-4  0.52
1984 Kothary RK, Jones D, Candido EP. 70-Kilodalton heat shock polypeptides from rainbow trout: characterization of cDNA sequences Molecular and Cellular Biology. 4: 1785-1791. PMID 6092938  0.52
1984 Kothary RK, Burgess EA, Candido EPM. The heat-shock phenomenon in cultured cells of rainbow trout hsp70 mRNA synthesis and turnover Bba - Gene Structure and Expression. 783: 137-143. DOI: 10.1016/0167-4781(84)90005-8  0.52
1982 Kothary RK, Candido EP. Induction of a novel set of polypeptides by heat shock or sodium arsenite in cultured cells of rainbow trout, Salmo gairdnerii Canadian Journal of Biochemistry. 60: 347-355. PMID 6805927  0.52
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