Takeshi Yagi, Ph.D. - Publications

Affiliations: 
Frontier Bioscience Osaka University, Toyonaka-shi, Ōsaka-fu, Japan 
Area:
molecular biology, protocadherin

114 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Asai H, Ohkawa N, Saitoh Y, Ghandour K, Murayama E, Nishizono H, Matsuo M, Hirayama T, Kaneko R, Muramatsu SI, Yagi T, Inokuchi K. Pcdhβ deficiency affects hippocampal CA1 ensemble activity and contextual fear discrimination. Molecular Brain. 13: 7. PMID 31959219 DOI: 10.1186/S13041-020-0547-Z  0.57
2019 Alvarez-Saavedra M, Yan K, De Repentigny Y, Hashem LE, Chaudary N, Sarwar S, Yang D, Ioshikhes I, Kothary R, Hirayama T, Yagi T, Picketts DJ. Snf2h Drives Chromatin Remodeling to Prime Upper Layer Cortical Neuron Development. Frontiers in Molecular Neuroscience. 12: 243. PMID 31680852 DOI: 10.3389/Fnmol.2019.00243  0.4
2018 Yamagishi T, Yoshitake K, Kamatani D, Watanabe K, Tsukano H, Hishida R, Takahashi K, Takahashi S, Horii A, Yagi T, Shibuki K. Molecular diversity of clustered protocadherin-α required for sensory integration and short-term memory in mice. Scientific Reports. 8: 9616. PMID 29941942 DOI: 10.1038/S41598-018-28034-4  0.348
2017 Katori S, Noguchi-Katori Y, Okayama A, Kawamura Y, Luo W, Sakimura K, Hirabayashi T, Iwasato T, Yagi T. Protocadherin-αC2 is required for diffuse projections of serotonergic axons. Scientific Reports. 7: 15908. PMID 29162883 DOI: 10.1038/S41598-017-16120-Y  0.303
2017 Onishi K, Uyeda A, Shida M, Hirayama T, Yagi T, Yamamoto N, Sugo N. Genome Stability by DNA polymerase β in Neural Progenitors Contributes to Neuronal Differentiation in Cortical Development. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28765330 DOI: 10.1523/Jneurosci.0665-17.2017  0.346
2017 Jiang Y, Loh YE, Rajarajan P, Hirayama T, Liao W, Kassim BS, Javidfar B, Hartley BJ, Kleofas L, Park RB, Labonte B, Ho SM, Chandrasekaran S, Do C, Ramirez BR, ... ... Yagi T, et al. The methyltransferase SETDB1 regulates a large neuron-specific topological chromatin domain. Nature Genetics. PMID 28671686 DOI: 10.1038/Ng.3906  0.54
2017 Nakamura F, Okada T, Shishikura M, Uetani N, Taniguchi M, Yagi T, Iwakura Y, Ohshima T, Goshima Y, Strittmatter SM. Protein Tyrosine Phosphatase δ mediates the Sema3A-induced cortical basal dendritic arborization through the activation of Fyn tyrosine kinase. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28637841 DOI: 10.1523/Jneurosci.2519-16.2017  0.338
2017 Hirayama T, Yagi T. Regulation of clustered protocadherin genes in individual neurons. Seminars in Cell & Developmental Biology. PMID 28591566 DOI: 10.1016/J.Semcdb.2017.05.026  0.357
2017 Hasegawa S, Kobayashi H, Kumagai M, Nishimaru H, Tarusawa E, Kanda H, Sanbo M, Yoshimura Y, Hirabayashi M, Hirabayashi T, Yagi T. Clustered Protocadherins Are Required for Building Functional Neural Circuits. Frontiers in Molecular Neuroscience. 10: 114. PMID 28484370 DOI: 10.3389/Fnmol.2017.00114  0.393
2017 Nakamura T, Nagata M, Yagi T, Graybiel AM, Yamamori T, Kitsukawa T. Learning New Sequential Stepping Patterns Requires Striatal Plasticity during the Earliest Phase of Acquisition. The European Journal of Neuroscience. PMID 28177160 DOI: 10.1111/Ejn.13537  0.303
2016 Hasegawa S, Kumagai M, Hagihara M, Nishimaru H, Hirano K, Kaneko R, Okayama A, Hirayama T, Sanbo M, Hirabayashi M, Watanabe M, Hirabayashi T, Yagi T. Distinct and Cooperative Functions for the Protocadherin-α, -β and -γ Clusters in Neuronal Survival and Axon Targeting. Frontiers in Molecular Neuroscience. 9: 155. PMID 28066179 DOI: 10.3389/Fnmol.2016.00155  0.337
2016 Tarusawa E, Sanbo M, Okayama A, Miyashita T, Kitsukawa T, Hirayama T, Hirabayashi T, Hasegawa S, Kaneko R, Toyoda S, Kobayashi T, Kato-Itoh M, Nakauchi H, Hirabayashi M, Yagi T, et al. Establishment of high reciprocal connectivity between clonal cortical neurons is regulated by the Dnmt3b DNA methyltransferase and clustered protocadherins. Bmc Biology. 14: 103. PMID 27912755 DOI: 10.1186/S12915-016-0326-6  0.331
2015 Meguro R, Hishida R, Tsukano H, Yoshitake K, Imamura R, Tohmi M, Kitsukawa T, Hirabayashi T, Yagi T, Takebayashi H, Shibuki K. Impaired clustered protocadherin-α leads to aggregated retinogeniculate terminals and impaired visual acuity in mice. Journal of Neurochemistry. 133: 66-72. PMID 25650227 DOI: 10.1111/Jnc.13053  0.316
2014 Hirabayashi T, Yagi T. Protocadherins in neurological diseases. Advances in Neurobiology. 8: 293-314. PMID 25300142 DOI: 10.1007/978-1-4614-8090-7_13  0.342
2014 Kaneko R, Abe M, Hirabayashi T, Uchimura A, Sakimura K, Yanagawa Y, Yagi T. Expansion of stochastic expression repertoire by tandem duplication in mouse Protocadherin-α cluster. Scientific Reports. 4: 6263. PMID 25179445 DOI: 10.1038/Srep06263  0.328
2014 Toyoda S, Kawaguchi M, Kobayashi T, Tarusawa E, Toyama T, Okano M, Oda M, Nakauchi H, Yoshimura Y, Sanbo M, Hirabayashi M, Hirayama T, Hirabayashi T, Yagi T. Developmental epigenetic modification regulates stochastic expression of clustered protocadherin genes, generating single neuron diversity. Neuron. 82: 94-108. PMID 24698270 DOI: 10.1016/J.Neuron.2014.02.005  0.388
2013 Yagi T. Genetic basis of neuronal individuality in the mammalian brain. Journal of Neurogenetics. 27: 97-105. PMID 23808929 DOI: 10.3109/01677063.2013.801969  0.36
2013 Hirayama T, Yagi T. Clustered protocadherins and neuronal diversity. Progress in Molecular Biology and Translational Science. 116: 145-67. PMID 23481194 DOI: 10.1016/B978-0-12-394311-8.00007-8  0.342
2012 Yamamoto M, Matsuzaki T, Takahashi R, Adachi E, Maeda Y, Yamaguchi S, Kitayama H, Echizenya M, Morioka Y, Alexander DB, Yagi T, Itohara S, Nakamura T, Akiyama H, Noda M. The transformation suppressor gene Reck is required for postaxial patterning in mouse forelimbs. Biology Open. 1: 458-66. PMID 23213437 DOI: 10.1242/Bio.2012638  0.335
2012 Hasegawa S, Hirabayashi T, Kondo T, Inoue K, Esumi S, Okayama A, Hamada S, Yagi T. Constitutively expressed Protocadherin-α regulates the coalescence and elimination of homotypic olfactory axons through its cytoplasmic region. Frontiers in Molecular Neuroscience. 5: 97. PMID 23087612 DOI: 10.3389/Fnmol.2012.00097  0.303
2012 Hirano K, Kaneko R, Izawa T, Kawaguchi M, Kitsukawa T, Yagi T. Single-neuron diversity generated by Protocadherin-β cluster in mouse central and peripheral nervous systems. Frontiers in Molecular Neuroscience. 5: 90. PMID 22969705 DOI: 10.3389/Fnmol.2012.00090  0.393
2012 Hirayama T, Tarusawa E, Yoshimura Y, Galjart N, Yagi T. CTCF is required for neural development and stochastic expression of clustered Pcdh genes in neurons. Cell Reports. 2: 345-57. PMID 22854024 DOI: 10.1016/J.Celrep.2012.06.014  0.411
2012 Yagi T. Molecular codes for neuronal individuality and cell assembly in the brain. Frontiers in Molecular Neuroscience. 5: 45. PMID 22518100 DOI: 10.3389/Fnmol.2012.00045  0.361
2011 Yokota S, Hirayama T, Hirano K, Kaneko R, Toyoda S, Kawamura Y, Hirabayashi M, Hirabayashi T, Yagi T. Identification of the cluster control region for the protocadherin-beta genes located beyond the protocadherin-gamma cluster. The Journal of Biological Chemistry. 286: 31885-95. PMID 21771796 DOI: 10.1074/Jbc.M111.245605  0.314
2011 Yagi T, Okayama A, Inoue Y, Toyoda S, Hirayama T, Hirabayashi T. Loss of function analysis in mice for all protocadherin clusters Neuroscience Research. 71: e95. DOI: 10.1016/J.Neures.2011.07.406  0.311
2009 Noguchi Y, Hirabayashi T, Katori S, Kawamura Y, Sanbo M, Hirabayashi M, Kiyonari H, Nakao K, Uchimura A, Yagi T. Total expression and dual gene-regulatory mechanisms maintained in deletions and duplications of the Pcdha cluster. The Journal of Biological Chemistry. 284: 32002-14. PMID 19797050 DOI: 10.1074/Jbc.M109.046938  0.376
2009 Katori S, Hamada S, Noguchi Y, Fukuda E, Yamamoto T, Yamamoto H, Hasegawa S, Yagi T. Protocadherin-alpha family is required for serotonergic projections to appropriately innervate target brain areas. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 9137-47. PMID 19625505 DOI: 10.1523/Jneurosci.5478-08.2009  0.351
2009 Yamagata Y, Kobayashi S, Umeda T, Inoue A, Sakagami H, Fukaya M, Watanabe M, Hatanaka N, Totsuka M, Yagi T, Obata K, Imoto K, Yanagawa Y, Manabe T, Okabe S. Kinase-dead knock-in mouse reveals an essential role of kinase activity of Ca2+/calmodulin-dependent protein kinase IIalpha in dendritic spine enlargement, long-term potentiation, and learning. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 7607-18. PMID 19515929 DOI: 10.1523/Jneurosci.0707-09.2009  0.316
2009 Hattori K, Fukuzako H, Hashiguchi T, Hamada S, Murata Y, Isosaka T, Yuasa S, Yagi T. Decreased expression of Fyn protein and disbalanced alternative splicing patterns in platelets from patients with schizophrenia. Psychiatry Research. 168: 119-28. PMID 19501919 DOI: 10.1016/J.Psychres.2008.04.014  0.305
2009 Uchimura A, Hidaka Y, Hirabayashi T, Hirabayashi M, Yagi T. DNA polymerase delta is required for early mammalian embryogenesis. Plos One. 4: e4184. PMID 19145245 DOI: 10.1371/Journal.Pone.0004184  0.34
2009 Hirano K, Kaneko R, Izawa T, Kitsukawa T, Yagi T. Differential and monoallelic gene exprssion of Protocadherin-β family genes in the mouse brain Neuroscience Research. 65: S150. DOI: 10.1016/J.Neures.2009.09.760  0.302
2008 Fukuda E, Hamada S, Hasegawa S, Katori S, Sanbo M, Miyakawa T, Yamamoto T, Yamamoto H, Hirabayashi T, Yagi T. Down-regulation of protocadherin-alpha A isoforms in mice changes contextual fear conditioning and spatial working memory. The European Journal of Neuroscience. 28: 1362-76. PMID 18973563 DOI: 10.1111/J.1460-9568.2008.06428.X  0.309
2008 Kaneko K, Tamamaki N, Owada H, Kakizaki T, Kume N, Totsuka M, Yamamoto T, Yawo H, Yagi T, Obata K, Yanagawa Y. Noradrenergic excitation of a subpopulation of GABAergic cells in the basolateral amygdala via both activation of nonselective cationic conductance and suppression of resting K+ conductance: a study using glutamate decarboxylase 67-green fluorescent protein knock-in mice. Neuroscience. 157: 781-97. PMID 18950687 DOI: 10.1016/J.Neuroscience.2008.09.029  0.35
2008 Yagi T. Clustered protocadherin family. Development, Growth & Differentiation. 50: S131-40. PMID 18430161 DOI: 10.1111/J.1440-169X.2008.00991.X  0.362
2008 Hasegawa S, Hamada S, Kumode Y, Esumi S, Katori S, Fukuda E, Uchiyama Y, Hirabayashi T, Mombaerts P, Yagi T. The protocadherin-alpha family is involved in axonal coalescence of olfactory sensory neurons into glomeruli of the olfactory bulb in mouse. Molecular and Cellular Neurosciences. 38: 66-79. PMID 18353676 DOI: 10.1016/J.Mcn.2008.01.016  0.32
2008 Kawaguchi M, Toyama T, Kaneko R, Hirayama T, Kawamura Y, Yagi T. Relationship between DNA methylation states and transcription of individual isoforms encoded by the protocadherin-alpha gene cluster. The Journal of Biological Chemistry. 283: 12064-75. PMID 18204046 DOI: 10.1074/Jbc.M709648200  0.306
2007 Morishita H, Yagi T. Protocadherin family: diversity, structure, and function. Current Opinion in Cell Biology. 19: 584-92. PMID 17936607 DOI: 10.1016/J.Ceb.2007.09.006  0.495
2007 Aiba A, Inokuchi K, Ishida Y, Itohara S, Kobayashi K, Masu M, Mishina M, Miyakawa T, Mori H, Nakao K, Obata Y, Sakimura K, Shiroishi T, Wada K, Yagi T. Mouse liaison for integrative brain research. Neuroscience Research. 58: 103-4. PMID 17382419 DOI: 10.1016/J.Neures.2007.02.012  0.476
2007 Okayama A, Kaneko R, Yagi T. Localization of Protocadherin-α protein in the mouse hippocampal neuron Neuroscience Research. 58: S205. DOI: 10.1016/J.Neures.2007.06.930  0.302
2007 Noguchi Y, Kawamura Y, Hirabayashi T, Uchimura A, Kawaguchi M, Katori S, Hirayama T, Yagi T. Exchange of genome structure in Protocadherin-α gene cluster alters their neuronal expression pattern Neuroscience Research. 58: S142. DOI: 10.1016/J.Neures.2007.06.1403  0.332
2007 Hirano K, Kaneko R, Izawa T, Kitsukawa T, Yagi T. Monoallelic gene regulation and combinatorial expression of Protocadherin-β family genes confer neuronal diversity in the brain Neuroscience Research. 58: S141. DOI: 10.1016/J.Neures.2007.06.1401  0.346
2006 Esumi S, Kaneko R, Kawamura Y, Yagi T. Split single-cell RT-PCR analysis of Purkinje cells. Nature Protocols. 1: 2143-51. PMID 17487206 DOI: 10.1038/Nprot.2006.343  0.32
2006 Morishita H, Umitsu M, Murata Y, Shibata N, Udaka K, Higuchi Y, Akutsu H, Yamaguchi T, Yagi T, Ikegami T. Structure of the cadherin-related neuronal receptor/protocadherin-alpha first extracellular cadherin domain reveals diversity across cadherin families. The Journal of Biological Chemistry. 281: 33650-63. PMID 16916795 DOI: 10.1074/Jbc.M603298200  0.499
2006 Yamashita H, Nakamura T, Takahashi T, Nagano Y, Hiji M, Hirabayashi T, Amano T, Yagi T, Sakai N, Kohriyama T, Matsumoto M. Embryonic stem cell-derived neuron models of Parkinson's disease exhibit delayed neuronal death. Journal of Neurochemistry. 98: 45-56. PMID 16805795 DOI: 10.1111/J.1471-4159.2006.03815.X  0.315
2006 Hirayama T, Yagi T. The role and expression of the protocadherin-alpha clusters in the CNS. Current Opinion in Neurobiology. 16: 336-42. PMID 16697637 DOI: 10.1016/J.Conb.2006.05.003  0.339
2006 Morita A, Yamashita N, Sasaki Y, Uchida Y, Nakajima O, Nakamura F, Yagi T, Taniguchi M, Usui H, Katoh-Semba R, Takei K, Goshima Y. Regulation of dendritic branching and spine maturation by semaphorin3A-Fyn signaling. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 2971-80. PMID 16540575 DOI: 10.1523/Jneurosci.5453-05.2006  0.382
2006 Isosaka T, Hattori K, Yagi T. NMDA-receptor proteins are upregulated in the hippocampus of postnatal heterozygous reeler mice. Brain Research. 1073: 11-9. PMID 16438943 DOI: 10.1016/J.Brainres.2005.12.049  0.36
2006 Kai N, Iwase K, Imai K, Nakahira E, Soma M, Ohtsuka S, Yagi T, Kobayashi K, Koga H, Takiguchi M, Yuasa S. Altered gene expression in the subdivisions of the amygdala of Fyn-deficient mice as revealed by laser capture microdissection and mKIAA cDNA array analysis. Brain Research. 1073: 60-70. PMID 16427614 DOI: 10.1016/J.Brainres.2005.12.042  0.374
2006 Hattori K, Uchino S, Isosaka T, Maekawa M, Iyo M, Sato T, Kohsaka S, Yagi T, Yuasa S. Fyn is required for haloperidol-induced catalepsy in mice. The Journal of Biological Chemistry. 281: 7129-35. PMID 16407246 DOI: 10.1074/Jbc.M511608200  0.345
2005 Osada T, Tamamaki N, Song SY, Kakazu N, Yamazaki Y, Makino H, Sasaki A, Hirayama T, Hamada S, Nave KA, Yanagimachi R, Yagi T. Developmental pluripotency of the nuclei of neurons in the cerebral cortex of juvenile mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 8368-74. PMID 16162918 DOI: 10.1523/Jneurosci.1591-05.2005  0.339
2005 Makino H, Yamazaki Y, Hirabayashi T, Kaneko R, Hamada S, Kawamura Y, Osada T, Yanagimachi R, Yagi T. Mouse embryos and chimera cloned from neural cells in the postnatal cerebral cortex. Cloning and Stem Cells. 7: 45-61. PMID 15996117 DOI: 10.1089/Clo.2005.7.45  0.375
2005 Umitsu M, Morishita H, Murata Y, Udaka K, Akutsu H, Yagi T, Ikegami T. 1H, 13C and 15N resonance assignments of the first cadherin domain of Cadherin-related neuronal receptor (CNR)/protocadherin alpha. Journal of Biomolecular Nmr. 31: 365-6. PMID 15929006 DOI: 10.1007/S10858-005-2450-4  0.471
2005 Taguchi Y, Koide T, Shiroishi T, Yagi T. Molecular evolution of cadherin-related neuronal receptor/protocadherin(alpha) (CNR/Pcdh(alpha)) gene cluster in Mus musculus subspecies. Molecular Biology and Evolution. 22: 1433-43. PMID 15758202 DOI: 10.1093/Molbev/Msi130  0.317
2005 Esumi S, Kakazu N, Taguchi Y, Hirayama T, Sasaki A, Hirabayashi T, Koide T, Kitsukawa T, Hamada S, Yagi T. Monoallelic yet combinatorial expression of variable exons of the protocadherin-alpha gene cluster in single neurons. Nature Genetics. 37: 171-6. PMID 15640798 DOI: 10.1038/Ng1500  0.389
2005 Ohsawa S, Hamada S, Kakinuma Y, Yagi T, Miura M. Novel function of neuronal PAS domain protein 1 in erythropoietin expression in neuronal cells. Journal of Neuroscience Research. 79: 451-8. PMID 15635607 DOI: 10.1002/Jnr.20365  0.351
2004 Morishita H, Kawaguchi M, Murata Y, Seiwa C, Hamada S, Asou H, Yagi T. Myelination triggers local loss of axonal CNR/protocadherin alpha family protein expression. The European Journal of Neuroscience. 20: 2843-7. PMID 15579137 DOI: 10.1111/J.1460-9568.2004.03803.X  0.487
2004 Morishita H, Murata Y, Esumi S, Hamada S, Yagi T. CNR/Pcdhalpha family in subplate neurons, and developing cortical connectivity. Neuroreport. 15: 2595-9. PMID 15570159 DOI: 10.1097/00001756-200412030-00007  0.537
2004 Hamaguchi-Hamada K, Hamada S, Yagi T. Exposure to hexanal odor induces extraordinary Fos expression in the medial preoptic area and amygdala of Fyn tyrosine kinase-deficient mice. Brain Research. Molecular Brain Research. 130: 187-90. PMID 15519689 DOI: 10.1016/J.Molbrainres.2004.07.006  0.318
2004 Kubota O, Hattori K, Hashimoto K, Yagi T, Sato T, Iyo M, Yuasa S. Auditory-conditioned-fear-dependent c-Fos expression is altered in the emotion-related brain structures of Fyn-deficient mice. Brain Research. Molecular Brain Research. 130: 149-60. PMID 15519685 DOI: 10.1016/J.Molbrainres.2004.07.018  0.36
2004 Tada MN, Senzaki K, Tai Y, Morishita H, Tanaka YZ, Murata Y, Ishii Y, Asakawa S, Shimizu N, Sugino H, Yagi T. Genomic organization and transcripts of the zebrafish Protocadherin genes. Gene. 340: 197-211. PMID 15475161 DOI: 10.1016/J.Gene.2004.07.014  0.491
2004 Murata Y, Hamada S, Morishita H, Mutoh T, Yagi T. Interaction with protocadherin-gamma regulates the cell surface expression of protocadherin-alpha. The Journal of Biological Chemistry. 279: 49508-16. PMID 15347688 DOI: 10.1074/Jbc.M408771200  0.484
2004 Sugino H, Toyama T, Taguchi Y, Esumi S, Miyazaki M, Yagi T. Negative and positive effects of an IAP-LTR on nearby Pcdaalpha gene expression in the central nervous system and neuroblastoma cell lines. Gene. 337: 91-103. PMID 15276205 DOI: 10.1016/J.Gene.2004.04.011  0.335
2004 Li C, Sasaki Y, Takei K, Yamamoto H, Shouji M, Sugiyama Y, Kawakami T, Nakamura F, Yagi T, Ohshima T, Goshima Y. Correlation between semaphorin3A-induced facilitation of axonal transport and local activation of a translation initiation factor eukaryotic translation initiation factor 4E. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 6161-70. PMID 15240808 DOI: 10.1523/Jneurosci.1476-04.2004  0.311
2004 Yuasa S, Hattori K, Yagi T. Defective neocortical development in Fyn-tyrosine-kinase-deficient mice. Neuroreport. 15: 819-22. PMID 15073522 DOI: 10.1097/00001756-200404090-00016  0.356
2003 Nakahara J, Tan-Takeuchi K, Seiwa C, Gotoh M, Kaifu T, Ujike A, Inui M, Yagi T, Ogawa M, Aiso S, Takai T, Asou H. Signaling via immunoglobulin Fc receptors induces oligodendrocyte precursor cell differentiation Developmental Cell. 4: 841-852. PMID 12791269 DOI: 10.1016/S1534-5807(03)00155-2  0.313
2003 Yagi T. Diversity of the cadherin-related neuronal receptor/protocadherin family and possible DNA rearrangement in the brain Genes to Cells. 8: 1-8. PMID 12558794 DOI: 10.1046/J.1365-2443.2003.00614.X  0.361
2002 Osada T, Kusakabe H, Akutsu H, Yagi T, Yanagimachi R. Adult murine neurons: Their chromatin and chromosome changes and failure to support embryonic development as revealed by nuclear transfer Cytogenetic and Genome Research. 97: 7-12. PMID 12438731 DOI: 10.1159/000064037  0.313
2002 Sasaki Y, Cheng C, Uchida Y, Nakajima O, Ohshima T, Yagi T, Taniguchi M, Nakayama T, Kishida R, Kudo Y, Ohno S, Nakamura F, Goshima Y. Fyn and Cdk5 mediate semaphorin-3A signaling, which is involved in regulation of dendrite orientation in cerebral cortex. Neuron. 35: 907-20. PMID 12372285 DOI: 10.1016/S0896-6273(02)00857-7  0.345
2002 Hironaka N, Yagi T, Niki H. Light-potentiation of acoustic startle response (ASR) and monoamine efflux related to fearfulness in Fyn-deficient mice. Brain Research. Molecular Brain Research. 98: 102-10. PMID 11834300 DOI: 10.1016/S0169-328X(01)00329-1  0.317
2002 Maekawa M, Toyama Y, Yasuda M, Yagi T, Yuasa S. Fyn tyrosine kinase in Sertoli cells is involved in mouse spermatogenesis. Biology of Reproduction. 66: 211-21. PMID 11751285 DOI: 10.1095/Biolreprod66.1.211  0.343
2001 Yamazaki Y, Makino H, Hamaguchi-Hamada K, Hamada S, Sugino H, Kawase E, Miyata T, Ogawa M, Yanagimachi R, Yagi T. Assessment of the developmental totipotency of neural cells in the cerebral cortex of mouse embryo by nuclear transfer. Proceedings of the National Academy of Sciences of the United States of America. 98: 14022-6. PMID 11698647 DOI: 10.1073/Pnas.231489398  0.305
2001 Hamada S, Yagi T. The cadherin-related neuronal receptor family: A novel diversified cadherin family at the synapse Neuroscience Research. 41: 207-215. PMID 11672833 DOI: 10.1016/S0168-0102(01)00281-4  0.368
2001 Hattori K, Yagi T, Maekawa M, Sato T, Yuasa S. N-Methyl-D-aspartate-induced c-Fos expression is enhanced in the forebrain structures related to emotion in Fyn-deficient mice. Brain Research. 905: 188-98. PMID 11423094 DOI: 10.1016/S0006-8993(01)02534-3  0.363
2001 Takei Y, Hamada S, Senzaki K, Mutoh T, Sugino H, Yagi T. Two novel CNRs from the CNR gene cluster have molecular features distinct from those of CNR1 to 8. Genomics. 72: 321-30. PMID 11401448 DOI: 10.1006/Geno.2000.6468  0.365
2001 Miyakawa T, Yagi T, Takao K, Niki H. Differential effect of Fyn tyrosine kinase deletion on offensive and defensive aggression. Behavioural Brain Research. 122: 51-6. PMID 11287076 DOI: 10.1016/S0166-4328(01)00171-1  0.337
2001 Hirayama T, Sugino H, Yagi T. Somatic mutations of synaptic cadherin (CNR family) transcripts in the nervous system. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. 6: 151-64. PMID 11260260 DOI: 10.1046/J.1365-2443.2001.00403.X  0.349
2001 Nakamura K, Manabe T, Watanabe M, Mamiya T, Ichikawa R, Kiyama Y, Sanbo M, Yagi T, Inoue Y, Nabeshima T, Mori H, Mishina M. Enhancement of hippocampal LTP, reference memory and sensorimotor gating in mutant mice lacking a telencephalon-specific cell adhesion molecule. The European Journal of Neuroscience. 13: 179-89. PMID 11135016 DOI: 10.1046/J.0953-816X.2000.01366.X  0.315
2000 Shima T, Yagi T, Isojima Y, Okumura N, Okada M, Nagai K. Changes in circadian period and morphology of the hypothalamic suprachiasmatic nucleus in fyn kinase-deficient mice. Brain Research. 870: 36-43. PMID 10869499 DOI: 10.1016/S0006-8993(00)02399-4  0.354
2000 Seiwa C, Sugiyama I, Yagi T, Iguchi T, Asou H. Fyn tyrosine kinase participates in the compact myelin sheath formation in the central nervous system. Neuroscience Research. 37: 21-31. PMID 10802341 DOI: 10.1016/S0168-0102(00)00100-0  0.314
2000 Kitazawa H, Katoh A, Yagi T, Nagao S. Dynamic characteristics and adaptability of reflex eye movements of Fyn-kinase-deficient mice. Neuroscience Letters. 280: 179-82. PMID 10675790 DOI: 10.1016/S0304-3940(00)00779-5  0.34
2000 Sugino H, Hamada S, Yasuda R, Tuji A, Matsuda Y, Fujita M, Yagi T. Genomic organization of the family of CNR cadherin genes in mice and humans. Genomics. 63: 75-87. PMID 10662547 DOI: 10.1006/Geno.1999.6066  0.365
2000 Yamazaki Y, Yagi T, Ozaki T, Imoto K. In vivo gene transfer to mouse spermatogenic cells using green fluorescent protein as a marker. Journal of Experimental Zoology. 286: 212-218. PMID 10617863 DOI: 10.1002/(Sici)1097-010X(20000201)286:2<212::Aid-Jez13>3.0.Co;2-C  0.327
2000 Senzaki K, Ogawa M, Yagi T. Proteins of the CNR family are multiple receptors for Reelin. Cell. 99: 635-47. PMID 10612399 DOI: 10.1016/S0092-8674(00)81552-4  0.35
1998 Kohmura N, Senzaki K, Hamada S, Kai N, Yasuda R, Watanabe M, Ishii H, Yasuda M, Mishina M, Yagi T. Diversity revealed by a novel family of cadherins expressed in neurons at a synaptic complex. Neuron. 20: 1137-51. PMID 9655502 DOI: 10.1016/S0896-6273(00)80495-X  0.37
1998 Kitazawa H, Yagi T, Miyakawa T, Niki H, Kawai N. Abnormal synaptic transmission in the olfactory bulb of Fyn-kinase-deficient mice. Journal of Neurophysiology. 79: 137-42. PMID 9425184 DOI: 10.1152/Jn.1998.79.1.137  0.338
1998 Taniguchi M, Sanbo M, Watanabe S, Naruse I, Mishina M, Yagi T. Efficient production of Cre-mediated site-directed recombinants through the utilization of the puromycin resistance gene, pac: A transient gene-integration marker for ES cells Nucleic Acids Research. 26: 679-680. PMID 9421534 DOI: 10.1093/Nar/26.2.679  0.317
1998 Nakamura K, Mori H, Kiyama Y, Yagi T, Manabe T, Takahashi T, Watanabe M, Ichikawa R, Inoue Y, Mishina M. Production and analysis of mutant mice carrying the Cre recombinase gene inserted into the telencephalin gene Neuroscience Research. 31: S312. DOI: 10.1016/S0168-0102(98)82430-9  0.328
1998 Miyakawa T, Yagi T, Niki H. Aggressiveness of fyn-deficient mice Neuroscience Research. 31: S260. DOI: 10.1016/S0168-0102(98)82149-4  0.313
1997 Kitsukawa T, Shimizu M, Sanbo M, Hirata T, Taniguchi M, Bekku Y, Yagi T, Fujisawa H. Neuropilin-semaphorin III/D-mediated chemorepulsive signals play a crucial role in peripheral nerve projection in mice. Neuron. 19: 995-1005. PMID 9390514 DOI: 10.1016/S0896-6273(00)80392-X  0.355
1997 Miyakawa T, Yagi T, Kitazawa H, Yasuda M, Kawai N, Tsuboi K, Niki H. Fyn-kinase as a determinant of ethanol sensitivity: relation to NMDA-receptor function. Science (New York, N.Y.). 278: 698-701. PMID 9381182 DOI: 10.1126/Science.278.5338.698  0.317
1997 Asada H, Kawamura Y, Maruyama K, Kume H, Ding R, Ji FY, Kanbara N, Kuzume H, Sanbo M, Yagi T, Obata K. Mice lacking the 65 kDa isoform of glutamic acid decarboxylase (GAD65) maintain normal levels of GAD67 and GABA in their brains but are susceptible to seizures. Biochemical and Biophysical Research Communications. 229: 891-5. PMID 8954991 DOI: 10.1006/Bbrc.1996.1898  0.305
1997 Yuasa S, Hattori K, Yagi T. 2217 Disorganization of calcium binding protein-immunoreactive neurons in the brain of the Fyn-deficient mice Neuroscience Research. 28: S255. DOI: 10.1016/S0168-0102(97)90702-1  0.333
1997 Kitsukawa T, Yagi T, Sanbo M, Fujisawa H. 1012 Neuropilin is an essential cell surface molecule in PNS axons guidance - a study in neuropilin-deficient mice Neuroscience Research. 28: S120. DOI: 10.1016/S0168-0102(97)90317-5  0.307
1997 Nakamoto Y, Miyakawa T, Yagi T, Niki H, Yoshii M. 263 Central-and periph in vitro quantitative autoradiographic studies of the eral-type benzodiazepine receptors in fyn-deficient mice Neuroscience Research. 28: S52. DOI: 10.1016/S0168-0102(97)90131-0  0.326
1996 Miyakawa T, Yagi T, Tateishi K, Niki H. Susceptibility to drug-induced seizures of Fyn tyrosine kinase-deficient mice. Neuroreport. 7: 2723-6. PMID 8981455 DOI: 10.1097/00001756-199611040-00063  0.304
1996 Kutsuwada T, Sakimura K, Manabe T, Takayama C, Katakura N, Kushiya E, Natsume R, Watanabe M, Inoue Y, Yagi T, Aizawa S, Arakawa M, Takahashi T, Nakamura Y, Mori H, et al. Impairment of suckling response, trigeminal neuronal pattern formation, and hippocampal LTD in NMDA receptor epsilon 2 subunit mutant mice. Neuron. 16: 333-44. PMID 8789948 DOI: 10.1016/S0896-6273(00)80051-3  0.355
1996 Ikeda K, Araki K, Takayama C, Inoue Y, Yagi T, Aizawa S, Mishina M. Reduced spontaneous activity of mice defective in the epsilon 4 subunit of the NMDA receptor channel. Brain Research. Molecular Brain Research. 33: 61-71. PMID 8774946 DOI: 10.1016/0169-328X(95)00107-4  0.353
1996 Miyakawa T, Yagi T, Kagiyama A, Niki H. Radial maze performance, open-field and elevated plus-maze behaviors in Fyn-kinase deficient mice: further evidence for increased fearfulness. Brain Research. Molecular Brain Research. 37: 145-50. PMID 8738145 DOI: 10.1016/0169-328X(95)00300-H  0.337
1996 Nakamoto Y, Yagi T, Niki H, Yoshii M. 339 Role of central- and peripheral-type benzodiazepine receptors in fear-response and seizure susceptibility in fyn-deficient and el mice Neuroscience Research. 25: S61. DOI: 10.1016/0168-0102(96)88724-4  0.301
1996 Kitazawa H, Yagi T, Shimazaki K, Miyakawa T, Niki H, Kawai N. 316 Abnormal synaptic transmission in the olfactory system in fyn-kinase deficient mice Neuroscience Research. 25: S53. DOI: 10.1016/0168-0102(96)88701-3  0.314
1995 Kashiwabuchi N, Ikeda K, Araki K, Hirano T, Shibuki K, Takayama C, Inoue Y, Kutsuwada T, Yagi T, Kang Y, Aizawa S, Mishina M. Impairment of motor coordination, Purkinje cell synapse formation, and cerebellar long-term depression in GluRδ2 mutant mice Cell. 81: 245-252. PMID 7736576 DOI: 10.1016/0092-8674(95)90334-8  0.304
1995 Yoshida M, Yagi T, Furuta Y, Takayanagi K, Kominami R, Takeda N, Tokunaga T, Chiba J, Ikawa Y, Aizawa S. A new strategy of gene trapping in ES cells using 3'RACE. Transgenic Research. 4: 277-87. PMID 7655516 DOI: 10.1007/Bf01969122  0.319
1995 Watanabe S, Kai N, Yasuda M, Kohmura N, Sanbo M, Mishina M, Yagi T. Stable Production Of Mutant Mice From Double Gene Converted Es Cells With Puromycin And Neomycin Biochemical and Biophysical Research Communications. 213: 130-137. PMID 7639726 DOI: 10.1006/Bbrc.1995.2107  0.315
1994 Yagi T, Aizawa S, Tokunaga T, Shigetani Y, Takeda N, Ikawa Y. A role for Fyn tyrosine kinase in the suckling behaviour of neonatal mice. Nature. 366: 742-5. PMID 8264796 DOI: 10.1038/366742A0  0.371
1994 Yagi T, Nada S, Watanabe N, Tamemoto H, Kohmura N, Ikawa Y, Aizawa S. A novel negative selection for homologous recombinants using diphtheria toxin A fragment gene. Analytical Biochemistry. 214: 77-86. PMID 8250258 DOI: 10.1006/Abio.1993.1459  0.336
1994 Kohmura N, Yagi T, Tomooka Y, Oyanagi M, Kominami R, Takeda N, Chiba J, Ikawa Y, Aizawa S. A novel nonreceptor tyrosine kinase, Srm: Cloning and targeted disruption Molecular and Cellular Biology. 14: 6915-6925. PMID 7935409 DOI: 10.1128/Mcb.14.10.6915  0.323
1994 Miyakawa T, Yagi T, Watanabe S, Niki H. Increased fearfulness of Fyn tyrosine kinase deficient mice. Brain Research. Molecular Brain Research. 27: 179-82. PMID 7877449 DOI: 10.1016/0169-328X(94)90201-1  0.345
1994 Miyakawa T, Yagi T, Niki H. Increased fearfulness in Fyn-deficient mice Neuroscience Research Supplements. 19: S99. DOI: 10.1016/0921-8696(94)92541-0  0.314
1994 Yagi T. A role for Fyn tyrosine kinase in the suckling behaviour of neonatal mice Trends in Genetics. 10: 77. DOI: 10.1016/0168-9525(94)90224-0  0.31
1993 Nada S, Yagi T, Takeda H, Tokunaga T, Nakagawa H, Ikawa Y, Okada M, Aizawa S. Constitutive activation of Src family kinases in mouse embryos that lack Csk. Cell. 73: 1125-35. PMID 8513497 DOI: 10.1016/0092-8674(93)90642-4  0.307
1992 Saga Y, Yagi T, Ikawa Y, Sakakura T, Aizawa S. Mice develop normally without tenascin. Genes & Development. 6: 1821-31. PMID 1383086 DOI: 10.1101/Gad.6.10.1821  0.358
1992 Horita K, Yagi T, Kohmura N, Tomooka Y, Ikawa Y, Aizawa S. A novel tyrosine kinase, hyk, expressed in murine embryonic stem cells. Biochemical and Biophysical Research Communications. 189: 1747-1753. PMID 1282811 DOI: 10.1016/0006-291X(92)90280-X  0.315
1990 Yagi T, Ikawa Y, Yoshida K, Shigetani Y, Takeda N, Mabuchi I, Yamamoto T, Aizawa S. Homologous recombination at c-fyn locus of mouse embryonic stem cells with use of diphtheria toxin A-fragment gene in negative selection. Proceedings of the National Academy of Sciences of the United States of America. 87: 9918-22. PMID 2263643 DOI: 10.1073/Pnas.87.24.9918  0.305
1990 Suda Y, Aizawa S, Furuta Y, Yagi T, Ikawa Y, Saitoh K, Yamada Y, Toyoshima K, Yamamoto T. Induction of a variety of tumors by c-erbB2 and clonal nature of lymphomas even with the mutated gene (Val659----Glu659). The Embo Journal. 9: 181-190. DOI: 10.1002/J.1460-2075.1990.Tb08094.X  0.324
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