Ek Han Tan - Publications

Affiliations: 
The University of Maine, Orono, ME, United States 

12/113 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Amundson KR, Ordoñez B, Santayana M, Tan EH, Henry IM, Mihovilovich E, Bonierbale M, Comai L. Genomic Outcomes of Haploid Induction Crosses in Potato ( L.). Genetics. PMID 31871130 DOI: 10.1534/Genetics.119.302843  0.351
2019 Comai L, Tan EH. Haploid Induction and Genome Instability. Trends in Genetics : Tig. PMID 31421911 DOI: 10.1016/J.Tig.2019.07.005  0.375
2018 Henry IM, Comai L, Tan EH. Detection of Chromothripsis in Plants. Methods in Molecular Biology (Clifton, N.J.). 1769: 119-132. PMID 29564821 DOI: 10.1007/978-1-4939-7780-2_8  0.37
2017 Wang J, Blevins T, Podicheti R, Haag JR, Tan EH, Wang F, Pikaard CS. Mutation of Arabidopsis SMC4 identifies condensin as a corepressor of pericentromeric transposons and conditionally expressed genes. Genes & Development. PMID 28882854 DOI: 10.1101/Gad.301499.117  0.525
2015 Kuppu S, Tan EH, Nguyen H, Rodgers A, Comai L, Chan SW, Britt AB. Point Mutations in Centromeric Histone Induce Post-zygotic Incompatibility and Uniparental Inheritance. Plos Genetics. 11: e1005494. PMID 26352591 DOI: 10.1371/Journal.Pgen.1005494  0.383
2015 Tan EH, Henry IM, Ravi M, Bradnam KR, Mandakova T, Marimuthu MP, Korf I, Lysak MA, Comai L, Chan SW. Catastrophic chromosomal restructuring during genome elimination in plants. Elife. 4. PMID 25977984 DOI: 10.7554/Elife.06516  0.384
2015 Maheshwari S, Tan EH, West A, Franklin FC, Comai L, Chan SW. Naturally occurring differences in CENH3 affect chromosome segregation in zygotic mitosis of hybrids. Plos Genetics. 11: e1004970. PMID 25622028 DOI: 10.1371/Journal.Pgen.1004970  0.404
2015 Tan EH, Henry IM, Ravi M, Bradnam KR, Mandakova T, Marimuthu MP, Korf I, Lysak MA, Comai L, Chan SW. Author response: Catastrophic chromosomal restructuring during genome elimination in plants Elife. DOI: 10.7554/Elife.06516.029  0.311
2014 Ravi M, Marimuthu MP, Tan EH, Maheshwari S, Henry IM, Marin-Rodriguez B, Urtecho G, Tan J, Thornhill K, Zhu F, Panoli A, Sundaresan V, Britt AB, Comai L, Chan SW. A haploid genetics toolbox for Arabidopsis thaliana. Nature Communications. 5: 5334. PMID 25358957 DOI: 10.1038/Ncomms6334  0.304
2012 Tan EH, Blevins T, Ream TS, Pikaard CS. Functional Consequences of Subunit Diversity in RNA Polymerases II and V Cell Reports. 1: 208-214. PMID 22550619 DOI: 10.1016/J.Celrep.2012.01.004  0.525
2011 Mosher RA, Tan EH, Shin J, Fischer RL, Pikaard CS, Baulcombe DC. An atypical epigenetic mechanism affects uniparental expression of Pol IV-dependent siRNAs. Plos One. 6: e25756. PMID 22003406 DOI: 10.1371/Journal.Pone.0025756  0.664
2011 Song J, Durrant WE, Wang S, Yan S, Tan EH, Dong X. DNA repair proteins are directly involved in regulation of gene expression during plant immune response. Cell Host & Microbe. 9: 115-24. PMID 21320694 DOI: 10.1016/J.Chom.2011.01.011  0.385
Low-probability matches (unlikely to be authored by this person)
2021 Amundson KR, Ordoñez B, Santayana M, Nganga ML, Henry IM, Bonierbale M, Khan A, Tan EH, Comai L. Rare instances of haploid inducer DNA in potato dihaploids and ploidy-dependent genome instability. The Plant Cell. PMID 33792719 DOI: 10.1093/plcell/koab100  0.245
2022 Hoopes G, Meng X, Hamilton JP, Achakkagari SR, de Alves Freitas Guesdes F, Bolger ME, Coombs JJ, Esselink D, Kaiser NR, Kodde L, Kyriakidou M, Lavrijssen B, van Lieshout N, Shereda R, Tuttle HK, ... ... Tan EH, et al. Phased, chromosome-scale genome assemblies of tetraploid potato reveals a complex genome, transcriptome, and predicted proteome landscape underpinning genetic diversity. Molecular Plant. PMID 35026436 DOI: 10.1016/j.molp.2022.01.003  0.234
2023 Tan EH, Ordoñez B, Thondehaalmath T, Seymour DK, Maloof JN, Maruthachalam R, Comai L. Establishment and inheritance of minichromosomes from Arabidopsis haploid induction. Chromosoma. PMID 36964786 DOI: 10.1007/s00412-023-00788-5  0.231
2001 Tan E, Ashizawa T. Genetic testing in spinocerebellar ataxias: defining a clinical role. Jama Neurology. 58: 191-195. PMID 11176956 DOI: 10.1001/Archneur.58.2.191  0.207
2021 Marimuthu MPA, Maruthachalam R, Bondada R, Kuppu S, Tan EH, Britt A, Chan SWL, Comai L. Epigenetically mismatched parental centromeres trigger genome elimination in hybrids. Science Advances. 7: eabk1151. PMID 34797718 DOI: 10.1126/sciadv.abk1151  0.197
2015 Tan EH, Henry IM, Ravi M, Bradnam KR, Mandakova T, Marimuthu MPA, Korf I, Lysak MA, Comai L, Chan SWL. Catastrophic chromosomal restructuring during genome elimination in plants Elife. 4. DOI: 10.7554/eLife.06516  0.193
2016 Tan E, Comai L, Henry I. Chromosome Dosage Analysis in Plants Using Whole Genome Sequencing Bio-Protocol. 6. DOI: 10.21769/BIOPROTOC.1854  0.172
2014 Tan DS, Camilleri-Broët S, Tan EH, Alifano M, Lim WT, Bobbio A, Zhang S, Ng QS, Ang MK, Iyer NG, Takano A, Lim KH, Régnard JF, Tan P, Broët P. Intertumor heterogeneity of non-small-cell lung carcinomas revealed by multiplexed mutation profiling and integrative genomics. International Journal of Cancer. Journal International Du Cancer. 135: 1092-100. PMID 24482041 DOI: 10.1002/ijc.28750  0.138
2017 Tan DSW, Chong FT, Leong HS, Toh SY, Lau DP, Kwang XL, Zhang X, Sundaram GM, Tan GS, Chang MM, Chua BT, Lim WT, Tan EH, Ang MK, Lim TKH, et al. Long noncoding RNA EGFR-AS1 mediates epidermal growth factor receptor addiction and modulates treatment response in squamous cell carcinoma. Nature Medicine. PMID 28920960 DOI: 10.1038/Nm.4401  0.128
2014 Tan EH, Morton JP, Timpson P, Tucci P, Melino G, Flores ER, Sansom OJ, Vousden KH, Muller PA. Functions of TAp63 and p53 in restraining the development of metastatic cancer. Oncogene. 33: 3325-33. PMID 23873029 DOI: 10.1038/onc.2013.287  0.127
2021 Ge T, Jiang H, Tan EH, Johnson SB, Larkin R, Charkowski AO, Secor G, Hao J. Pangenomic Analysis of Strains Related to the Outbreak of Blackleg and Soft Rot of Potato in USA. Plant Disease. PMID 34213964 DOI: 10.1094/PDIS-03-21-0587-RE  0.124
2017 Phua T, Sng MK, Tan EH, Chee DS, Li Y, Wee JW, Teo Z, Chan JS, Lim MM, Tan CK, Zhu P, Arulampalam V, Tan NS. Angiopoietin-like 4 Mediates Colonic Inflammation by Regulating Chemokine Transcript Stability via Tristetraprolin. Scientific Reports. 7: 44351. PMID 28287161 DOI: 10.1038/srep44351  0.112
2012 Ng KP, Hillmer AM, Chuah CT, Juan WC, Ko TK, Teo AS, Ariyaratne PN, Takahashi N, Sawada K, Fei Y, Soh S, Lee WH, Huang JW, Allen JC, Woo XY, ... ... Tan EH, et al. A common BIM deletion polymorphism mediates intrinsic resistance and inferior responses to tyrosine kinase inhibitors in cancer. Nature Medicine. 18: 521-8. PMID 22426421 DOI: 10.1038/Nm.2713  0.11
2012 Tan EH, Razak SA, Abdullah JM, Mohamed Yusoff AA. De-novo mutations and genetic variation in the SCN1A gene in Malaysian patients with generalized epilepsy with febrile seizures plus (GEFS+). Epilepsy Research. 102: 210-5. PMID 22944210 DOI: 10.1016/j.eplepsyres.2012.08.004  0.108
2016 Klughammer B, Brugger W, Cappuzzo F, Ciuleanu T, Mok T, Reck M, Tan EH, Delmar P, Klingelschmitt G, Yin AY, Spleiss O, Wu L, Shames DS. Examining Treatment Outcomes with Erlotinib in Patients with Advanced Non-Small-Cell Lung Cancer Whose Tumors Harbor Uncommon Epidermal Growth Factor Receptors Mutations. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. PMID 26773740 DOI: 10.1016/J.Jtho.2015.12.107  0.102
2017 Marvalim C, Wong JX, Sutiman N, Lim WT, Tan SW, Kanesvaran R, Ng QS, Jain A, Ang MK, Tan WL, Toh CK, Tan EH, Chowbay B. Influence of the KDM4A rs586339 polymorphism on overall survival in Asian non-small-cell lung cancer patients. Pharmacogenetics and Genomics. PMID 28059867 DOI: 10.1097/FPC.0000000000000266  0.097
2015 Ma BB, Goh BC, Lim WT, Hui EP, Tan EH, Lopes GL, Lo KW, Li L, Loong H, Foster NR, Erlichman C, King AD, Kam MK, Leung SF, Chan KC, et al. Multicenter phase II study of the AKT inhibitor MK-2206 in recurrent or metastatic nasopharyngeal carcinoma from patients in the mayo phase II consortium and the cancer therapeutics research group (MC1079). Investigational New Drugs. PMID 26084990 DOI: 10.1007/s10637-015-0264-0  0.097
2012 Ng C, Guan MSH, Koh C, Ouyang X, Yu F, Tan E, O'Neill SP, Zhang X, Chung J, Lim K. AMP Kinase Activation Mitigates Dopaminergic Dysfunction and Mitochondrial Abnormalities in Drosophila Models of Parkinson's Disease The Journal of Neuroscience. 32: 14311-14317. PMID 23055502 DOI: 10.1523/Jneurosci.0499-12.2012  0.097
2017 Fumagalli A, Drost J, Suijkerbuijk SJ, van Boxtel R, de Ligt J, Offerhaus GJ, Begthel H, Beerling E, Tan EH, Sansom OJ, Cuppen E, Clevers H, van Rheenen J. Genetic dissection of colorectal cancer progression by orthotopic transplantation of engineered cancer organoids. Proceedings of the National Academy of Sciences of the United States of America. PMID 28270604 DOI: 10.1073/Pnas.1701219114  0.094
2016 Tan WL, Jain A, Takano A, Newell EW, Iyer NG, Lim WT, Tan EH, Zhai W, Hillmer AM, Tam WL, Tan DS. Novel therapeutic targets on the horizon for lung cancer. The Lancet. Oncology. 17: e347-62. PMID 27511159 DOI: 10.1016/S1470-2045(16)30123-1  0.089
2016 Yoo EH, Park KJ, Won HH, Park JH, Park JH, Lee ST, Kim HJ, Bang SM, Chi HS, Jung CW, Kim SH, Yun H, Sun CH, Park I, Lee S, ... ... Tan EH, et al. Genetic Characteristics of Polycythemia Vera and Essential Thrombocythemia in Korean Patients. Journal of Clinical Laboratory Analysis. PMID 27132877 DOI: 10.1002/jcla.21981  0.087
2012 Zhuo J, Tan EH, Yan B, Tochhawng L, Jayapal M, Koh S, Tay HK, Maciver SK, Hooi SC, Salto-Tellez M, Kumar AP, Goh YC, Lim YC, Yap CT. Gelsolin induces colorectal tumor cell invasion via modulation of the urokinase-type plasminogen activator cascade. Plos One. 7: e43594. PMID 22927998 DOI: 10.1371/Journal.Pone.0043594  0.086
2011 Tan EH, Lloyd-Jones GC, Harvey JN, Lennox AJ, Mills BM. [(RCN)2PdCl2]-catalyzed E/Z isomerization of alkenes: a non-hydride binuclear addition-elimination pathway. Angewandte Chemie (International Ed. in English). 50: 9602-6. PMID 21938759 DOI: 10.1002/Anie.201103947  0.085
2017 Soh SX, Siddiqui FJ, Allen JC, Kim GW, Lee JC, Yatabe Y, Soda M, Mano H, Soo RA, Chin TM, Ebi H, Yano S, Matsuo K, Niu X, Lu S, ... ... Tan EH, et al. A systematic review and meta-analysis of individual patient data on the impact of the BIM deletion polymorphism on treatment outcomes in epidermal growth factor receptor mutant lung cancer. Oncotarget. PMID 28467813 DOI: 10.18632/oncotarget.17102  0.083
2011 Broët P, Dalmasso C, Tan EH, Alifano M, Zhang S, Wu J, Lee MH, Régnard JF, Lim D, Koong HN, Agasthian T, Miller LD, Lim E, Camilleri-Broët S, Tan P. Genomic profiles specific to patient ethnicity in lung adenocarcinoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 3542-50. PMID 21521776 DOI: 10.1158/1078-0432.CCR-10-2185  0.078
2016 Ho YS, Yip LY, Basri N, Chong VS, Teo CC, Tan E, Lim KL, Tan GS, Yang X, Yeo SY, Koh MS, Devanand A, Takano A, Tan EH, Tan DS, et al. Lipidomic Profiling of Lung Pleural Effusion Identifies Unique Metabotype for EGFR Mutants in Non-Small Cell Lung Cancer. Scientific Reports. 6: 35110. PMID 27739449 DOI: 10.1038/srep35110  0.078
2016 Ahmad I, Mui E, Galbraith L, Patel R, Tan EH, Salji M, Rust AG, Repiscak P, Hedley A, Markert E, Loveridge C, van der Weyden L, Edwards J, Sansom OJ, Adams DJ, et al. Sleeping Beauty screen reveals Pparg activation in metastatic prostate cancer. Proceedings of the National Academy of Sciences of the United States of America. PMID 27357679 DOI: 10.1073/Pnas.1601571113  0.077
2014 Bennouna J, Havel L, Krzakowski M, Kollmeier J, Gervais R, Dansin E, Serke M, Favaretto A, Szczesna A, Cobo M, Ciuffreda L, Jassem J, Nicolini M, Ramlau R, Amoroso D, ... ... Tan EH, et al. Oral vinorelbine plus cisplatin as first-line chemotherapy in nonsquamous non-small-cell lung cancer: final results of an International randomized phase II study (NAVotrial 01). Clinical Lung Cancer. 15: 258-65. PMID 24954228 DOI: 10.1016/j.cllc.2014.04.007  0.077
2010 Krzakowski M, Ramlau R, Jassem J, Szczesna A, Zatloukal P, Von Pawel J, Sun X, Bennouna J, Santoro A, Biesma B, Delgado FM, Salhi Y, Vaissiere N, Hansen O, Tan EH, et al. Phase III trial comparing vinflunine with docetaxel in second-line advanced non-small-cell lung cancer previously treated with platinum-containing chemotherapy. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 28: 2167-73. PMID 20351334 DOI: 10.1200/JCO.2009.23.4146  0.077
2013 Tan CK, Tan EH, Luo B, Huang CL, Loo JS, Choong C, Tan NS. SMAD3 deficiency promotes inflammatory aortic aneurysms in angiotensin II-infused mice via activation of iNOS. Journal of the American Heart Association. 2: e000269. PMID 23782924 DOI: 10.1161/JAHA.113.000269  0.076
2012 Manegold C, van Zandwijk N, Szczesna A, Zatloukal P, Au JS, Blasinska-Morawiec M, Serwatowski P, Krzakowski M, Jassem J, Tan EH, Benner RJ, Ingrosso A, Meech SJ, Readett D, Thatcher N. A phase III randomized study of gemcitabine and cisplatin with or without PF-3512676 (TLR9 agonist) as first-line treatment of advanced non-small-cell lung cancer. Annals of Oncology : Official Journal of the European Society For Medical Oncology / Esmo. 23: 72-7. PMID 21464154 DOI: 10.1093/annonc/mdr030  0.076
2014 Tan DS, Haaland B, Gan JM, Tham SC, Sinha I, Tan EH, Lim KH, Takano A, Krisna SS, Thu MM, Liew HP, Ullrich A, Lim WT, Chua BT. Bosutinib inhibits migration and invasion via ACK1 in KRAS mutant non-small cell lung cancer. Molecular Cancer. 13: 13. PMID 24461128 DOI: 10.1186/1476-4598-13-13  0.072
2015 Kundu P, Genander M, Strååt K, Classon J, Ridgway RA, Tan EH, Björk J, Martling A, van Es J, Sansom OJ, Clevers H, Pettersson S, Frisén J. An EphB-Abl signaling pathway is associated with intestinal tumor initiation and growth. Science Translational Medicine. 7: 281ra44. PMID 25834110 DOI: 10.1126/Scitranslmed.3010567  0.071
2013 Tan DS, Montoya J, Ng QS, Chan KS, Lynette O, Sakktee Krisna S, Takano A, Lim WT, Tan EH, Lim KH. Molecular profiling for druggable genetic abnormalities in carcinoma of unknown primary. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 31: e237-9. PMID 23547070 DOI: 10.1200/JCO.2012.44.3937  0.07
2017 Kannan S, Pradhan MR, Tiwari G, Tan WC, Chowbay B, Tan EH, Tan DS, Verma C. Hydration effects on the efficacy of the Epidermal growth factor receptor kinase inhibitor afatinib. Scientific Reports. 7: 1540. PMID 28484248 DOI: 10.1038/S41598-017-01491-Z  0.069
2016 Aix SP, Park K, Tan EH, O'Byrne K, Zhang L, Boyer M, Mok T, Hirsh V, Chih-Hsin Yang J, Märten A, Paz-Ares L. P1.34: First-Line Afatinib vs Gefitinib for Patients With EGFR Mutation-Positive Non-Small-Cell Lung Cancer: The LUX-Lung 7 Trial: Track: Advanced NSCLC. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 11: S203-S204. PMID 27676520 DOI: 10.1016/J.Jtho.2016.08.056  0.067
2016 Simoni Y, Fehlings M, Kløverpris HN, McGovern N, Koo SL, Loh CY, Lim S, Kurioka A, Fergusson JR, Tang CL, Kam MH, Dennis K, Lim TK, Fui AC, Hoong CW, ... ... Tan EH, et al. Human Innate Lymphoid Cell Subsets Possess Tissue-Type Based Heterogeneity in Phenotype and Frequency. Immunity. PMID 27986455 DOI: 10.1016/J.Immuni.2016.11.005  0.067
2016 Park K, Tan EH, O'Byrne K, Zhang L, Boyer M, Mok T, Hirsh V, Yang JC, Lee KH, Lu S, Shi Y, Kim SW, Laskin J, Kim DW, Arvis CD, et al. Afatinib versus gefitinib as first-line treatment of patients with EGFR mutation-positive non-small-cell lung cancer (LUX-Lung 7): a phase 2B, open-label, randomised controlled trial. The Lancet. Oncology. PMID 27083334 DOI: 10.1016/S1470-2045(16)30033-X  0.065
2011 Reck M, Hermes A, Tan EH, Felip E, Klughammer B, Baselga J. Tissue sampling in lung cancer: A review in light of the MERIT experience Lung Cancer. 74: 1-6. PMID 21658788 DOI: 10.1016/j.lungcan.2011.05.002  0.064
2011 Chan A, Tan EH. How well does the MESTT correlate with CTCAE scale for the grading of dermatological toxicities associated with oral tyrosine kinase inhibitors? Supportive Care in Cancer. 19: 1667-1674. PMID 20820812 DOI: 10.1007/s00520-010-0999-2  0.064
2016 Sutiman N, Tan SW, Tan EH, Lim WT, Kanesvaran R, Ng QS, Jain A, Ang MK, Tan WL, Toh CK, Chowbay B. EGFR mutation subtypes influence survival outcomes following first-line gefitinib therapy in advanced Asian NSCLC patients. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. PMID 27908825 DOI: 10.1016/j.jtho.2016.11.2225  0.064
2016 Elbediwy A, Vincent-Mistiaen ZI, Spencer-Dene B, Stone RK, Boeing S, Wculek SK, Cordero J, Tan EH, Ridgway R, Brunton VG, Sahai E, Gerhardt H, Behrens A, Malanchi I, Sansom OJ, et al. Integrin signalling regulates YAP/TAZ to control skin homeostasis. Development (Cambridge, England). PMID 26989177 DOI: 10.1242/Dev.133728  0.062
2012 Tan EH, Yusoff AA, Abdullah JM, Razak SA. Generalized epilepsy with febrile seizure plus (GEFS+) spectrum: Novel de novo mutation of SCN1A detected in a Malaysian patient. Journal of Pediatric Neurosciences. 7: 123-5. PMID 23248692 DOI: 10.4103/1817-1745.102575  0.062
2012 Chia WK, Wang WW, Teo M, Tai WM, Lim WT, Tan EH, Leong SS, Sun L, Chen JJ, Gottschalk S, Toh HC. A phase II study evaluating the safety and efficacy of an adenovirus-ΔLMP1-LMP2 transduced dendritic cell vaccine in patients with advanced metastatic nasopharyngeal carcinoma. Annals of Oncology : Official Journal of the European Society For Medical Oncology / Esmo. 23: 997-1005. PMID 21821548 DOI: 10.1093/annonc/mdr341  0.061
2012 Miller VA, Hirsh V, Cadranel J, Chen YM, Park K, Kim SW, Zhou C, Su WC, Wang M, Sun Y, Heo DS, Crino L, Tan EH, Chao TY, Shahidi M, et al. Afatinib versus placebo for patients with advanced, metastatic non-small-cell lung cancer after failure of erlotinib, gefitinib, or both, and one or two lines of chemotherapy (LUX-Lung 1): a phase 2b/3 randomised trial. The Lancet. Oncology. 13: 528-38. PMID 22452896 DOI: 10.1016/S1470-2045(12)70087-6  0.059
2014 Chew SC, Lim J, Singh O, Chen X, Tan EH, Lee EJ, Chowbay B. Pharmacogenetic effects of regulatory nuclear receptors (PXR, CAR, RXRα and HNF4α) on docetaxel disposition in Chinese nasopharyngeal cancer patients. European Journal of Clinical Pharmacology. 70: 155-66. PMID 24193570 DOI: 10.1007/s00228-013-1596-3  0.058
2013 Lee CK, Brown C, Gralla RJ, Hirsh V, Thongprasert S, Tsai CM, Tan EH, Ho JC, Chu da T, Zaatar A, Osorio Sanchez JA, Vu VV, Au JS, Inoue A, Lee SM, et al. Impact of EGFR inhibitor in non-small cell lung cancer on progression-free and overall survival: a meta-analysis. Journal of the National Cancer Institute. 105: 595-605. PMID 23594426 DOI: 10.1093/jnci/djt072  0.058
2012 Tan EH, Goh C, Lim WT, Soo KC, Khoo ML, Tan T, Tan DS, Ang MK, Ng QS, Tan PH, Lim A, Hwang J, Teng YH, Lim TH, Tan SH, et al. Gefitinib, cisplatin, and concurrent radiotherapy for locally advanced head and neck cancer: EGFR FISH, protein expression, and mutational status are not predictive biomarkers. Annals of Oncology : Official Journal of the European Society For Medical Oncology / Esmo. 23: 1010-6. PMID 21768327 DOI: 10.1093/annonc/mdr327  0.057
2011 Lim WT, Ng QS, Ivy P, Leong SS, Singh O, Chowbay B, Gao F, Thng CH, Goh BC, Tan DS, Koh TS, Toh CK, Tan EH. A Phase II study of pazopanib in Asian patients with recurrent/metastatic nasopharyngeal carcinoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 5481-9. PMID 21712450 DOI: 10.1158/1078-0432.CCR-10-3409  0.057
2016 Park K, Tan EH, Zhang L, Hirsh V, O'Byrne K, Boyer M, Yang J, Mok T, Kim M, Paz-Ares L. 140PD: LUX-Lung 7: A Phase IIb, global, randomised, open-label trial of afatinib vs gefitinib as first-line treatment for patients (pts) with advanced non-small cell lung cancer (NSCLC) harbouring activating EGFR mutations. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 11: S117-8. PMID 27198277 DOI: 10.1016/S1556-0864(16)30250-7  0.055
2017 Paz-Ares L, Tan EH, O'Byrne K, Zhang L, Hirsh V, Boyer M, Yang JC, Mok T, Lee KH, Lu S, Shi Y, Lee DH, Laskin J, Kim DW, Laurie SA, et al. Afatinib versus gefitinib in patients with EGFR mutation-positive advanced non-small-cell lung cancer: overall survival data from the phase IIb LUX-Lung 7 trial. Annals of Oncology : Official Journal of the European Society For Medical Oncology. 28: 270-277. PMID 28426106 DOI: 10.1093/annonc/mdw611  0.054
2016 Rajasekaran T, Ng QS, Shao-Weng Tan D, Lim WT, Ang MK, Toh CK, Chowbay B, Kanesvaran R, Tan EH. Metronomic Chemotherapy: A Relook At Its Basis and Rationale. Cancer Letters. PMID 28003122 DOI: 10.1016/j.canlet.2016.12.013  0.054
2016 Wong MT, Ong DE, Lim FS, Teng KW, McGovern N, Narayanan S, Ho WQ, Cerny D, Tan HK, Anicete R, Tan BK, Lim TK, Chan CY, Cheow PC, Lee SY, ... ... Tan EH, ... ... Tan EY, et al. A High-Dimensional Atlas of Human T Cell Diversity Reveals Tissue-Specific Trafficking and Cytokine Signatures. Immunity. PMID 27521270 DOI: 10.1016/j.immuni.2016.07.007  0.053
2016 Kam Mok TS, Geater SL, Su WC, Tan EH, Yang JC, Chang GC, Han M, Komarnitsky P, Payumo F, Garrus JE, Close S, Park K. A randomized phase 2 study comparing the combination of ficlatuzumab and gefitinib with gefitinib alone in Asian patients with advanced stage pulmonary adenocarcinoma. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. PMID 27448761 DOI: 10.1016/j.jtho.2016.05.038  0.052
2011 Lee AW, Tung SY, Ngan RK, Chappell R, Chua DT, Lu TX, Siu L, Tan T, Chan LK, Ng WT, Leung TW, Fu YT, Au GK, Zhao C, O'Sullivan B, ... Tan EH, et al. Factors contributing to the efficacy of concurrent-adjuvant chemotherapy for locoregionally advanced nasopharyngeal carcinoma: combined analyses of NPC-9901 and NPC-9902 Trials. European Journal of Cancer (Oxford, England : 1990). 47: 656-66. PMID 21112774 DOI: 10.1016/J.Ejca.2010.10.026  0.051
2006 Tan EK, Lu ZY, Fook-Chong SMC, Tan E, Shen H, Chua E, Yih Y, Teo YY, Zhao Y. Exploring an interaction of adenosine A2A receptor variability with coffee and tea intake in Parkinson's disease American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics. 141: 634-636. PMID 16823803 DOI: 10.1002/ajmg.b.30359  0.051
2014 Chia WK, Teo M, Wang WW, Lee B, Ang SF, Tai WM, Chee CL, Ng J, Kan R, Lim WT, Tan SH, Ong WS, Cheung YB, Tan EH, Connolly JE, et al. Adoptive T-cell transfer and chemotherapy in the first-line treatment of metastatic and/or locally recurrent nasopharyngeal carcinoma. Molecular Therapy : the Journal of the American Society of Gene Therapy. 22: 132-9. PMID 24297049 DOI: 10.1038/mt.2013.242  0.048
2014 Ang SH, Haaland B, Acharyya S, Thu MM, Krisna SS, Hwang SG, Tan PH, Ng QS, Tan DS, Tai WM, Tan EH, Lim WT, Ang MK. Interactions between clinical factors, p16, and cyclin-D1 expression and survival outcomes in oropharyngeal and hypopharyngeal squamous cell carcinoma. Head & Neck. PMID 24953865 DOI: 10.1002/hed.23803  0.047
2012 Tan EH, Sansom OJ. A new tumour suppressor enters the network of intestinal progenitor cell homeostasis Embo Journal. 31: 2444-2445. PMID 22510881 DOI: 10.1038/emboj.2012.115  0.046
2015 Heigener DF, Pereira JR, Felip E, Mazal J, Manzyuk L, Tan EH, Merimsky O, Sarholz B, Esser R, Gatzemeier U. Weekly and every 2 weeks cetuximab maintenance therapy after platinum-based chemotherapy plus cetuximab as first-line treatment for non-small cell lung cancer: randomized non-comparative phase IIIb NEXT trial. Targeted Oncology. 10: 255-65. PMID 25195590 DOI: 10.1007/s11523-014-0336-7  0.046
2016 Zhang WC, Chin TM, Yang H, Nga ME, Lunny DP, Lim EK, Sun LL, Pang YH, Leow YN, Malusay SR, Lim PX, Lee JZ, Tan BJ, Shyh-Chang N, Lim EH, ... ... Tan EH, et al. Tumour-initiating cell-specific miR-1246 and miR-1290 expression converge to promote non-small cell lung cancer progression. Nature Communications. 7: 11702. PMID 27325363 DOI: 10.1038/Ncomms11702  0.046
2011 Tan IB, Cutcutache I, Zang ZJ, Iqbal J, Yap SF, Hwang W, Lim WT, Teh BT, Rozen S, Tan EH, Tan P. Fanconi's anemia in adulthood: Chemoradiation-induced bone marrow failure and a novel FANCA mutation identified by targeted deep sequencing Journal of Clinical Oncology. 29. PMID 21519011 DOI: 10.1200/JCO.2011.35.1064  0.046
2015 Iyer NG, Tan DS, Tan VK, Wang W, Hwang J, Tan NC, Sivanandan R, Tan HK, Lim WT, Ang MK, Wee J, Soo KC, Tan EH. Randomized trial comparing surgery and adjuvant radiotherapy versus concurrent chemoradiotherapy in patients with advanced, nonmetastatic squamous cell carcinoma of the head and neck: 10-year update and subset analysis. Cancer. 121: 1599-607. PMID 25639864 DOI: 10.1002/cncr.29251  0.045
2017 Aw DC, Tan EH, Chin TM, Lim HL, Lee HY, Soo RA. Management of epidermal growth factor receptor tyrosine kinase inhibitor-related cutaneous and gastrointestinal toxicities. Asia-Pacific Journal of Clinical Oncology. PMID 28464435 DOI: 10.1111/ajco.12687  0.045
2016 Sutiman N, Zhang Z, Tan EH, Ang MK, Tan SD, Toh CK, Ng QS, Chowbay B, Lim WT. Phase I Study of Oral Vinorelbine in Combination with Erlotinib in Advanced Non-Small Cell Lung Cancer (NSCLC) Using Two Different Schedules. Plos One. 11: e0154316. PMID 27135612 DOI: 10.1371/journal.pone.0154316  0.045
2016 Tan WL, Tan EH, Lim DW, Ng QS, Tan DS, Jain A, Ang MK. Advances in systemic treatment for nasopharyngeal carcinoma. Chinese Clinical Oncology. 5: 21. PMID 27121881 DOI: 10.21037/cco.2016.03.03  0.044
2014 Tan DC, Chin WW, Tan EH, Hong S, Gu W, Gokhale R. Effect of binders on the release rates of direct molded verapamil tablets using twin-screw extruder in melt granulation. International Journal of Pharmaceutics. 463: 89-97. PMID 24406670 DOI: 10.1016/j.ijpharm.2013.12.053  0.042
2015 Li L, Chong HC, Ng SY, Kwok KW, Teo Z, Tan EH, Choo CC, Seet JE, Choi HW, Buist ML, Chow VT, Tan NS. Angiopoietin-like 4 Increases Pulmonary Tissue Leakiness and Damage during Influenza Pneumonia. Cell Reports. PMID 25660016 DOI: 10.1016/j.celrep.2015.01.011  0.041
2011 Lee AW, Tung SY, Chan AT, Chappell R, Fu YT, Lu TX, Tan T, Chua DT, O'Sullivan B, Tung R, Ng WT, Leung TW, Leung SF, Yau S, Zhao C, ... Tan EH, et al. A randomized trial on addition of concurrent-adjuvant chemotherapy and/or accelerated fractionation for locally-advanced nasopharyngeal carcinoma. Radiotherapy and Oncology : Journal of the European Society For Therapeutic Radiology and Oncology. 98: 15-22. PMID 20971520 DOI: 10.1016/J.Radonc.2010.09.023  0.04
2011 Tan EH, Goss GD, Salgia R, Besse B, Gandara DR, Hanna NH, Yang JC, Thertulien R, Wertheim M, Mazieres J, Hensing T, Lee C, Gupta N, Pradhan R, Qian J, et al. Phase 2 trial of Linifanib (ABT-869) in patients with advanced non-small cell lung cancer. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 6: 1418-25. PMID 21597387 DOI: 10.1097/Jto.0B013E318220C93E  0.038
2015 Jain A, Lim C, Gan EM, Ng DZ, Ng QS, Ang MK, Takano A, Chan KS, Tan WM, Kanesvaran R, Toh CK, Loo CM, Hsu AA, Devanand A, Lim CH, ... ... Tan EH, et al. Impact of Smoking and Brain Metastasis on Outcomes of Advanced EGFR Mutation Lung Adenocarcinoma Patients Treated with First Line Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors. Plos One. 10: e0123587. PMID 25955322 DOI: 10.1371/journal.pone.0123587  0.036
2015 Tan EH, Tan DS, Li WY, Haaland B, Ang MK, Chau NM, Toh CK, Tan IB, Koh TS, Thng CH, Chowbay B, Hui KM, Lim WT, Ng QS. Metronomic vinorelbine (oral) in combination with sorafenib in advanced non-small cell lung cancer. Lung Cancer (Amsterdam, Netherlands). 88: 289-96. PMID 25896396 DOI: 10.1016/j.lungcan.2015.04.001  0.035
2011 Ngeow J, Lim WT, Leong SS, Ang MK, Toh CK, Gao F, Chowbay B, Tan EH. Docetaxel is effective in heavily pretreated patients with disseminated nasopharyngeal carcinoma Annals of Oncology. 22: 718-722. PMID 20716628 DOI: 10.1093/annonc/mdq425  0.034
2012 Tan CK, Chong HC, Tan EH, Tan NS. Getting 'Smad' about obesity and diabetes. Nutrition & Diabetes. 2: e29. PMID 23449528 DOI: 10.1038/nutd.2012.1  0.032
2013 Cheung YT, Shwe M, Tan EH, Chui WK, Ng R, Chan A. Acknowledging the relevance of cognitive changes in cancer patients: perspectives of oncology practitioners in Asia. Journal of Cancer Survivorship : Research and Practice. 7: 146-54. PMID 23392850 DOI: 10.1007/s11764-012-0256-4  0.03
2012 Ng QS, Thng CH, Lim WT, Hartono S, Thian YL, Lee PS, Tan DS, Tan EH, Koh TS. Dynamic contrast-enhanced computed tomography in metastatic nasopharyngeal carcinoma: reproducibility analysis and observer variability of the distributed parameter model. Investigative Radiology. 47: 5-10. PMID 21577128 DOI: 10.1097/RLI.0b013e3182199b9a  0.026
2017 Loveridge C, Mui E, Patel R, Tan EH, Ahmad I, Welsh M, Galbraith J, Hedley A, Nixon C, Blyth K, Sansom OJ, Leung HY. Increased T cell infiltration elicited by Erk5 deletion in a Pten-deficient mouse model of prostate carcinogenesis. Cancer Research. PMID 28515147 DOI: 10.1158/0008-5472.CAN-16-2565  0.026
2011 Toh HC, Chia WK, Sun L, Thng CH, Soe Y, Phoon YP, Yap SP, Lim WT, Tai WM, Hee SW, Tan SH, Leong SS, Tan EH. Graft-vs-tumor effect in patients with advanced nasopharyngeal cancer treated with nonmyeloablative allogeneic PBSC transplantation. Bone Marrow Transplantation. 46: 573-9. PMID 20661236 DOI: 10.1038/bmt.2010.161  0.025
2012 Cheung YT, Tan EH, Chan A. An evaluation on the neuropsychological tests used in the assessment of postchemotherapy cognitive changes in breast cancer survivors. Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer. 20: 1361-75. PMID 22476439 DOI: 10.1007/s00520-012-1445-4  0.023
2015 Hsu AA, Tan EH, Takano AM. Lower Respiratory Tract Adenoid Cystic Carcinoma: Its Management in the Past Decades. Clinical Oncology (Royal College of Radiologists (Great Britain)). PMID 26160258 DOI: 10.1016/j.clon.2015.06.012  0.023
2017 Tan EH, Parmentier J, Low A, Möschwitzer JP. Downstream drug product processing of itraconazole nanosuspension: Factors influencing tablet material properties and dissolution of compacted nanosuspension-layered sugar beads. International Journal of Pharmaceutics. PMID 28859940 DOI: 10.1016/j.ijpharm.2017.08.107  0.022
2016 Ng DZ, Tan WL, Ong WS, Gan EM, Jain A, Tan EH, Tan D. 139PD: Lifetime incidence of brain metastases (BM) in EGFR-mutant (M+) lung cancer treated with first-line EGFR TKIs. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 11: S117. PMID 27198278 DOI: 10.1016/S1556-0864(16)30249-0  0.022
2011 Kao YH, Tan EH, Teo TK, Ng CE, Goh SW. Imaging discordance between hepatic angiography versus Tc-99m-MAA SPECT/CT: a case series, technical discussion and clinical implications. Annals of Nuclear Medicine. 25: 669-76. PMID 21766243 DOI: 10.1007/s12149-011-0516-9  0.02
2010 Christianson MD, Tan EH, Landis CR. Stopped-flow NMR: determining the kinetics of [rac-(C2H4(1-indenyl)2)ZrMe][MeB(C6F5)3]-catalyzed polymerization of 1-hexene by direct observation. Journal of the American Chemical Society. 132: 11461-3. PMID 20672801 DOI: 10.1021/Ja105107Y  0.019
2015 Tai WM, Lim C, Ahmad A, Ong WS, Choo SP, Lim WT, Tan EH, Kanesvaran R, Tan DS. Do elderly patients benefit from enrollment into Phase I Trials? Journal of Geriatric Oncology. 6: 241-8. PMID 25779876 DOI: 10.1016/j.jgo.2015.02.003  0.019
2016 Velentzis LS, Banks E, Sitas F, Salagame U, Tan EH, Canfell K. Use of Menopausal Hormone Therapy and Bioidentical Hormone Therapy in Australian Women 50 to 69 Years of Age: Results from a National, Cross-Sectional Study. Plos One. 11: e0146494. PMID 27008039 DOI: 10.1371/journal.pone.0146494  0.018
2014 Chin WW, Parmentier J, Widzinski M, Tan EH, Gokhale R. A brief literature and patent review of nanosuspensions to a final drug product. Journal of Pharmaceutical Sciences. 103: 2980-99. PMID 25099918 DOI: 10.1002/jps.24098  0.018
2016 Rannan-Eliya RP, Anuranga C, Manual A, Sararaks S, Jailani AS, Hamid AJ, Razif IM, Tan EH, Darzi A. Improving Health Care Coverage, Equity, And Financial Protection Through A Hybrid System: Malaysia's Experience. Health Affairs (Project Hope). 35: 838-46. PMID 27140990 DOI: 10.1377/Hlthaff.2015.0863  0.016
2017 Parmentier J, Tan EH, Low A, Moeschwitzer JP. Down-stream drug product processing of itraconazole nanosuspension: Factors influencing drug particle size and dissolution from nanosuspension-layered beads. International Journal of Pharmaceutics. PMID 28400290 DOI: 10.1016/j.ijpharm.2017.04.012  0.015
2011 Kao YH, Tan EH, Ng CE, Goh SW. Clinical implications of the body surface area method versus partition model dosimetry for yttrium-90 radioembolization using resin microspheres: a technical review. Annals of Nuclear Medicine. 25: 455-61. PMID 21643807 DOI: 10.1007/s12149-011-0499-6  0.014
2010 Tan EH, Goh SW. Exploring new frontiers in molecular imaging: Emergence of Ga PET/CT. World Journal of Radiology. 2: 55-67. PMID 21160919 DOI: 10.4329/wjr.v2.i2.55  0.012
2012 Kao YH, Tan EH, Lim KY, Ng CE, Goh SW. Yttrium-90 internal pair production imaging using first generation PET/CT provides high-resolution images for qualitative diagnostic purposes. The British Journal of Radiology. 85: 1018-9. PMID 21976634 DOI: 10.1259/bjr/33524085  0.011
2012 Tan IB, Pang GS, Yee A, Tan SH, Tan EH, Tan MH. Exploring the benefits of early access to palliative care in advanced lung cancer: living better, living longer, or both? Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 30: 2163-4; author reply. PMID 22547599 DOI: 10.1200/JCO.2012.41.8582  0.01
2012 Tan CH, Tan EH. Post-treatment Assessment of Glioblastoma Multiforme: Imaging with Fluorodeoxyglucose, Sestamibi, and Choline. World Journal of Nuclear Medicine. 11: 30-2. PMID 22942782 DOI: 10.4103/1450-1147.98745  0.01
2012 Chew SC, Sandanaraj E, Singh O, Chen X, Tan EH, Lim WT, Lee EJ, Chowbay B. Influence of SLCO1B3 haplotype-tag SNPs on docetaxel disposition in Chinese nasopharyngeal cancer patients. British Journal of Clinical Pharmacology. 73: 606-18. PMID 21995462 DOI: 10.1111/j.1365-2125.2011.04123.x  0.01
2011 Kao YH, Tan EH, Ng CE, Goh SW. Yttrium-90 time-of-flight PET/CT is superior to Bremsstrahlung SPECT/CT for postradioembolization imaging of microsphere biodistribution. Clinical Nuclear Medicine. 36: e186-7. PMID 22064104 DOI: 10.1097/RLU.0b013e31821c9a11  0.01
2011 Tan EH, Tan CH. Imaging of gastroenteropancreatic neuroendocrine tumors. World Journal of Clinical Oncology. 2: 28-43. PMID 21603312 DOI: 10.5306/wjco.v2.i1.28  0.01
2011 Yu CY, Ang GY, Chua AL, Tan EH, Lee SY, Falero-Diaz G, Otero O, Rodríguez I, Reyes F, Acosta A, Sarmiento ME, Ghosh S, Ramamurthy T, Yean Yean C, Lalitha P, et al. Dry-reagent gold nanoparticle-based lateral flow biosensor for the simultaneous detection of Vibrio cholerae serogroups O1 and O139. Journal of Microbiological Methods. 86: 277-82. PMID 21571011 DOI: 10.1016/j.mimet.2011.04.020  0.01
2011 Lim TC, Tan EH, Zaheer S. Use of Ga-68 DOTATATE PET/CT to confirm portal vein tumor thrombosis in a patient with pancreatic neuroendocrine tumor. Clinical Nuclear Medicine. 36: 498-9. PMID 21552039 DOI: 10.1097/RLU.0b013e318217398b  0.01
2011 Chew SC, Singh O, Chen X, Ramasamy RD, Kulkarni T, Lee EJ, Tan EH, Lim WT, Chowbay B. The effects of CYP3A4, CYP3A5, ABCB1, ABCC2, ABCG2 and SLCO1B3 single nucleotide polymorphisms on the pharmacokinetics and pharmacodynamics of docetaxel in nasopharyngeal carcinoma patients. Cancer Chemotherapy and Pharmacology. 67: 1471-8. PMID 21468756 DOI: 10.1007/s00280-011-1625-9  0.01
2010 Chia WK, Wang WW, Lim WT, Tai WM, Sun L, Thng CH, Soe Y, Yap SP, Tan EH, Toh HC. Nonmyeloablative allogeneic stem cell transplantation for nasopharyngeal carcinoma. The Oncologist. 15: 1192-7. PMID 20980417 DOI: 10.1634/theoncologist.2010-0204  0.01
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