| Year |
Citation |
Score |
| 2021 |
Griffiths WJ, Abdel-Khalik J, Moore SF, Wijeyekoon RS, Crick PJ, Yutuc E, Farrell K, Breen DP, Williams-Gray CH, Theofilopoulos S, Arenas E, Trupp M, Barker RA, Wang Y. The Cerebrospinal Fluid Profile of Cholesterol Metabolites in Parkinson's Disease and Their Association With Disease State and Clinical Features. Frontiers in Aging Neuroscience. 13: 685594. PMID 34526889 DOI: 10.3389/fnagi.2021.685594 |
0.463 |
|
| 2020 |
Yutuc E, Angelini R, Baumert M, Mast N, Pikuleva I, Newton J, Clench MR, Skibinski DOF, Howell OW, Wang Y, Griffiths WJ. Localization of sterols and oxysterols in mouse brain reveals distinct spatial cholesterol metabolism. Proceedings of the National Academy of Sciences of the United States of America. PMID 32132201 DOI: 10.1073/Pnas.1917421117 |
0.338 |
|
| 2019 |
Griffiths WJ, Wang Y. Sterolomics in biology, biochemistry, medicine. Trends in Analytical Chemistry : Trac. 120: 115280. PMID 31839688 DOI: 10.1016/J.Trac.2018.10.016 |
0.345 |
|
| 2019 |
Griffiths WJ, Wang Y. Oxysterols as Lipid Mediators: Their Biosynthetic Genes, Enzymes and Metabolites. Prostaglandins & Other Lipid Mediators. 106381. PMID 31698146 DOI: 10.1016/J.Prostaglandins.2019.106381 |
0.309 |
|
| 2019 |
Crick PJ, Yutuc E, Abdel-Khalik J, Saeed A, Betsholtz C, Genove G, Björkhem I, Wang Y, Griffiths WJ. Formation and Metabolism of Oxysterols and Cholestenoic acids Found in the Mouse Circulation: Lessons Learnt from Deuterium-Enrichment Experiments and the CYP46A1 Transgenic Mouse. The Journal of Steroid Biochemistry and Molecular Biology. 105475. PMID 31541728 DOI: 10.1016/J.Jsbmb.2019.105475 |
0.337 |
|
| 2019 |
Meljon A, Crick PJ, Yutuc E, Yau JL, Seckl JR, Theofilopoulos S, Arenas E, Wang Y, Griffiths WJ. Mining for Oxysterols in Mouse Brain and Plasma: Relevance to Spastic Paraplegia Type 5. Biomolecules. 9. PMID 31013940 DOI: 10.3390/biom9040149 |
0.524 |
|
| 2019 |
Abdel-Khalik J, Crick PJ, Yutuc E, Wang Y, Griffiths WJ. Developing an Enzyme-Assisted Derivatization Method for Analysis of C Bile Alcohols and Acids by Electrospray Ionization-Mass Spectrometry. Molecules (Basel, Switzerland). 24. PMID 30736477 DOI: 10.3390/Molecules24030597 |
0.326 |
|
| 2019 |
Theofilopoulos S, Abreu de Oliveira WA, Yang S, Yutuc E, Saeed A, Abdel-Khalik J, Ullgren A, Cedazo-Minguez A, Björkhem I, Wang Y, Griffiths WJ, Arenas E. 24(),25-Epoxycholesterol and () overexpression promote midbrain dopaminergic neurogenesis . The Journal of Biological Chemistry. PMID 30655290 DOI: 10.1074/Jbc.Ra118.005639 |
0.529 |
|
| 2018 |
Griffiths WJ, Crick PJ, Meljon A, Theofilopoulos S, Abdel-Khalik J, Yutuc E, Parker JE, Kelly DE, Kelly SL, Arenas E, Wang Y. Additional pathways of sterol metabolism: Evidence from analysis of Cyp27a1-/- mouse brain and plasma. Biochimica Et Biophysica Acta. Molecular and Cell Biology of Lipids. PMID 30471425 DOI: 10.1016/J.Bbalip.2018.11.006 |
0.571 |
|
| 2018 |
Abdel-Khalik J, Crick PJ, Yutuc E, DeBarber AE, Duell PB, Steiner RD, Laina I, Wang Y, Griffiths WJ. Identification of 7α,24-Dihydroxy-3-oxocholest-4-en-26-oic and 7α,25-Dihydroxy-3-oxocholest-4-en-26-oic Acids in Human Cerebrospinal Fluid and Plasma. Biochimie. PMID 29960034 DOI: 10.1016/J.Biochi.2018.06.020 |
0.316 |
|
| 2017 |
Rees DO, Crick PJ, Jenkins GJ, Wang Y, Griffiths WJ, Brown TH, Al-Sarireh B. Comparison of the composition of bile acids in bile of patients with adenocarcinoma of the pancreas and benign disease. The Journal of Steroid Biochemistry and Molecular Biology. PMID 29031685 DOI: 10.1016/J.Jsbmb.2017.10.011 |
0.335 |
|
| 2017 |
Griffiths WJ, Hearn T, Crick PJ, Abdel-Khalik J, Dickson A, Yutuc E, Wang Y. Charge-Tagging Liquid Chromatography-Mass Spectrometry Methodology Targeting Oxysterol Diastereoisomers. Chemistry and Physics of Lipids. PMID 28411018 DOI: 10.1016/J.Chemphyslip.2017.04.004 |
0.35 |
|
| 2017 |
Griffiths WJ, Wang Y. Sterolomics: State of the Art, Developments, Limitations and Challenges. Biochimica Et Biophysica Acta. PMID 28302589 DOI: 10.1016/J.Bbalip.2017.03.001 |
0.302 |
|
| 2017 |
Griffiths WJ, Abdel-Khalik J, Yutuc E, Morgan AH, Gilmore I, Hearn T, Wang Y. Cholesterolomics: An update. Analytical Biochemistry. PMID 28087213 DOI: 10.1016/J.Ab.2017.01.009 |
0.366 |
|
| 2016 |
Crick PJ, Griffiths WJ, Zhang J, Beibel M, Abdel-Khalik J, Kuhle J, Sailer AW, Wang Y. Reduced Plasma Levels of 25-Hydroxycholesterol and Increased Cerebrospinal Fluid Levels of Bile Acid Precursors in Multiple Sclerosis Patients. Molecular Neurobiology. PMID 27878760 DOI: 10.1007/S12035-016-0281-9 |
0.329 |
|
| 2016 |
Abdel-Khalik J, Yutuc E, Crick PJ, Gustafsson JÅ, Warner M, Roman G, Talbot K, Gray E, Griffiths WJ, Turner MR, Wang Y. Defective cholesterol metabolism in amyotrophic lateral sclerosis. Journal of Lipid Research. PMID 27811233 DOI: 10.1194/Jlr.P071639 |
0.316 |
|
| 2015 |
Griffiths WJ, Abdel-Khalik J, Crick PJ, Yutuc E, Wang Y. New methods for analysis of oxysterols and related compounds by LC-MS. The Journal of Steroid Biochemistry and Molecular Biology. PMID 26639636 DOI: 10.1016/J.Jsbmb.2015.11.017 |
0.383 |
|
| 2015 |
Crick PJ, Bentley TW, Wang Y, Griffiths WJ. Revised sample preparation for the analysis of oxysterols by enzyme-assisted derivatisation for sterol analysis (EADSA). Analytical and Bioanalytical Chemistry. 407: 5235-9. PMID 25796527 DOI: 10.1007/S00216-015-8609-2 |
0.319 |
|
| 2015 |
Crick PJ, Beckers L, Baes M, Van Veldhoven PP, Wang Y, Griffiths WJ. The oxysterol and cholestenoic acid profile of mouse cerebrospinal fluid. Steroids. 99: 172-7. PMID 25759118 DOI: 10.1016/J.Steroids.2015.02.021 |
0.335 |
|
| 2015 |
Iuliano L, Crick PJ, Zerbinati C, Tritapepe L, Abdel-Khalik J, Poirot M, Wang Y, Griffiths WJ. Cholesterol metabolites exported from human brain. Steroids. 99: 189-93. PMID 25668615 DOI: 10.1016/J.Steroids.2015.01.026 |
0.352 |
|
| 2015 |
Crick PJ, William Bentley T, Abdel-Khalik J, Matthews I, Clayton PT, Morris AA, Bigger BW, Zerbinati C, Tritapepe L, Iuliano L, Wang Y, Griffiths WJ. Quantitative charge-tags for sterol and oxysterol analysis. Clinical Chemistry. 61: 400-11. PMID 25512642 DOI: 10.1373/Clinchem.2014.231332 |
0.331 |
|
| 2014 |
Theofilopoulos S, Griffiths WJ, Crick PJ, Yang S, Meljon A, Ogundare M, Kitambi SS, Lockhart A, Tuschl K, Clayton PT, Morris AA, Martinez A, Reddy MA, Martinuzzi A, Bassi MT, et al. Cholestenoic acids regulate motor neuron survival via liver X receptors. The Journal of Clinical Investigation. 124: 4829-42. PMID 25271621 DOI: 10.1172/Jci68506 |
0.535 |
|
| 2014 |
Wang Y, Karu K, Meljon A, Turton J, Yau JL, Seckl JR, Wang Y, Griffiths WJ. 24S,25-Epoxycholesterol in mouse and rat brain. Biochemical and Biophysical Research Communications. 449: 229-34. PMID 24832732 DOI: 10.1016/J.Bbrc.2014.05.012 |
0.308 |
|
| 2014 |
Autio KJ, Schmitz W, Nair RR, Selkälä EM, Sormunen RT, Miinalainen IJ, Crick PJ, Wang Y, Griffiths WJ, Reddy JK, Baes M, Hiltunen JK. Role of AMACR (α-methylacyl-CoA racemase) and MFE-1 (peroxisomal multifunctional enzyme-1) in bile acid synthesis in mice. The Biochemical Journal. 461: 125-35. PMID 24735479 DOI: 10.1042/Bj20130915 |
0.307 |
|
| 2014 |
Dai D, Mills PB, Footitt E, Gissen P, McClean P, Stahlschmidt J, Coupry I, Lavie J, Mochel F, Goizet C, Mizuochi T, Kimura A, Nittono H, Schwarz K, Crick PJ, ... ... Griffiths WJ, et al. Liver disease in infancy caused by oxysterol 7 α-hydroxylase deficiency: successful treatment with chenodeoxycholic acid. Journal of Inherited Metabolic Disease. 37: 851-61. PMID 24658845 DOI: 10.1007/S10545-014-9695-6 |
0.36 |
|
| 2014 |
Rigdova K, Wang Y, Ward M, Griffiths WJ. A new derivative for oxosteroid analysis by mass spectrometry. Biochemical and Biophysical Research Communications. 446: 762-7. PMID 24525129 DOI: 10.1016/J.Bbrc.2014.01.190 |
0.364 |
|
| 2014 |
Crick PJ, Aponte J, Bentley TW, Matthews I, Wang Y, Griffiths WJ. Evaluation of novel derivatisation reagents for the analysis of oxysterols. Biochemical and Biophysical Research Communications. 446: 756-61. PMID 24525124 DOI: 10.1016/J.Bbrc.2014.01.173 |
0.374 |
|
| 2013 |
Liebisch G, Vizcaíno JA, Köfeler H, Trötzmüller M, Griffiths WJ, Schmitz G, Spener F, Wakelam MJ. Shorthand notation for lipid structures derived from mass spectrometry. Journal of Lipid Research. 54: 1523-30. PMID 23549332 DOI: 10.1194/Jlr.M033506 |
0.329 |
|
| 2013 |
Meljon A, Watson GL, Wang Y, Shackleton CH, Griffiths WJ. Analysis by liquid chromatography-mass spectrometry of sterols and oxysterols in brain of the newborn Dhcr7(Δ3-5/T93M) mouse: a model of Smith-Lemli-Opitz syndrome. Biochemical Pharmacology. 86: 43-55. PMID 23500538 DOI: 10.1016/J.Bcp.2013.03.003 |
0.326 |
|
| 2013 |
Theofilopoulos S, Wang Y, Kitambi SS, Sacchetti P, Sousa KM, Bodin K, Kirk J, Saltó C, Gustafsson M, Toledo EM, Karu K, Gustafsson JÅ, Steffensen KR, Ernfors P, Sjövall J, ... Griffiths WJ, et al. Brain endogenous liver X receptor ligands selectively promote midbrain neurogenesis. Nature Chemical Biology. 9: 126-33. PMID 23292650 DOI: 10.1038/Nchembio.1156 |
0.531 |
|
| 2013 |
Griffiths WJ, Crick PJ, Wang Y, Ogundare M, Tuschl K, Morris AA, Bigger BW, Clayton PT, Wang Y. Analytical strategies for characterization of oxysterol lipidomes: liver X receptor ligands in plasma. Free Radical Biology & Medicine. 59: 69-84. PMID 22846477 DOI: 10.1016/J.Freeradbiomed.2012.07.027 |
0.336 |
|
| 2012 |
Meljon A, Theofilopoulos S, Shackleton CH, Watson GL, Javitt NB, Knölker HJ, Saini R, Arenas E, Wang Y, Griffiths WJ. Analysis of bioactive oxysterols in newborn mouse brain by LC/MS. Journal of Lipid Research. 53: 2469-83. PMID 22891291 DOI: 10.1194/Jlr.D028233 |
0.557 |
|
| 2011 |
Rai DK, Brunton NP, Koidis A, Rawson A, McLoughlin P, Griffiths WJ. Characterisation of polyacetylenes isolated from carrot (Daucus carota) extracts by negative ion tandem mass spectrometry Rapid Communications in Mass Spectrometry : Rcm. 25: 2231-2239. PMID 21735506 DOI: 10.1002/Rcm.5103 |
0.328 |
|
| 2011 |
Griffiths WJ, Wang Y. Analysis of oxysterol metabolomes. Biochimica Et Biophysica Acta. 1811: 784-99. PMID 21718802 DOI: 10.1016/J.Bbalip.2011.05.012 |
0.37 |
|
| 2011 |
Karu K, Turton J, Wang Y, Griffiths WJ. Nano-liquid chromatography-tandem mass spectrometry analysis of oxysterols in brain: monitoring of cholesterol autoxidation. Chemistry and Physics of Lipids. 164: 411-24. PMID 21575613 DOI: 10.1016/J.Chemphyslip.2011.04.011 |
0.365 |
|
| 2011 |
Griffiths WJ, Ogundare M, Williams CM, Wang Y. On the future of "omics": lipidomics. Journal of Inherited Metabolic Disease. 34: 583-92. PMID 21318352 DOI: 10.1007/S10545-010-9274-4 |
0.306 |
|
| 2011 |
Theofilopoulos S, Karu K, Kitambi S, Sacchetti P, Sousa K, Sjovall J, Griffiths W, Arenas E. Identification and characterisation of endogenous LXR ligands in ventral midbrain development Neuroscience Research. 71: e50. DOI: 10.1016/J.Neures.2011.07.211 |
0.498 |
|
| 2010 |
Griffiths WJ, Koal T, Wang Y, Kohl M, Enot DP, Deigner HP. Targeted metabolomics for biomarker discovery. Angewandte Chemie (International Ed. in English). 49: 5426-45. PMID 20629054 DOI: 10.1002/Anie.200905579 |
0.315 |
|
| 2010 |
Griffiths WJ, Sjövall J. Analytical strategies for characterization of bile acid and oxysterol metabolomes. Biochemical and Biophysical Research Communications. 396: 80-4. PMID 20494115 DOI: 10.1016/J.Bbrc.2010.02.149 |
0.352 |
|
| 2010 |
Griffiths WJ, Sjövall J. Bile acids: analysis in biological fluids and tissues. Journal of Lipid Research. 51: 23-41. PMID 20008121 DOI: 10.1194/Jlr.R001941-Jlr200 |
0.379 |
|
| 2010 |
Ogundare M, Theofilopoulos S, Lockhart A, Hall LJ, Arenas E, Sjövall J, Brenton AG, Wang Y, Griffiths WJ. Cerebrospinal fluid steroidomics: are bioactive bile acids present in brain? The Journal of Biological Chemistry. 285: 4666-79. PMID 19996111 DOI: 10.1074/Jbc.M109.086678 |
0.554 |
|
| 2009 |
Seibert C, Davidson BR, Fuller BJ, Patterson LH, Griffiths WJ, Wang Y. Multiple-approaches to the identification and quantification of cytochromes P450 in human liver tissue by mass spectrometry. Journal of Proteome Research. 8: 1672-81. PMID 19714871 DOI: 10.1021/Pr800795R |
0.343 |
|
| 2009 |
Griffiths WJ, Wang Y. Analysis of neurosterols by GC-MS and LC-MS/MS. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 877: 2778-805. PMID 19560986 DOI: 10.1016/J.Jchromb.2009.05.017 |
0.335 |
|
| 2009 |
Griffiths WJ, Wang Y. Mass spectrometry: from proteomics to metabolomics and lipidomics. Chemical Society Reviews. 38: 1882-96. PMID 19551169 DOI: 10.1039/B618553N |
0.352 |
|
| 2009 |
Liere P, Pianos A, Eychenne B, Cambourg A, Bodin K, Griffiths W, Schumacher M, Baulieu E, Sjövall J. Analysis of pregnenolone and dehydroepiandrosterone in rodent brain: cholesterol autoxidation is the key Journal of Lipid Research. 50: 2430-2444. PMID 19506304 DOI: 10.1194/Jlr.M900162-Jlr200 |
0.344 |
|
| 2009 |
Wang Y, Sousa KM, Bodin K, Theofilopoulos S, Sacchetti P, Hornshaw M, Woffendin G, Karu K, Sjövall J, Arenas E, Griffiths WJ. Targeted lipidomic analysis of oxysterols in the embryonic central nervous system. Molecular Biosystems. 5: 529-41. PMID 19381367 DOI: 10.1039/B819502A |
0.562 |
|
| 2009 |
Smyth R, Lane CS, Ashiq R, Turton JA, Clarke CJ, Dare TO, York MJ, Griffiths W, Munday MR. Proteomic investigation of urinary markers of carbon-tetrachloride-induced hepatic fibrosis in the Hanover Wistar rat. Cell Biology and Toxicology. 25: 499-512. PMID 18777138 DOI: 10.1007/S10565-008-9104-8 |
0.312 |
|
| 2008 |
Griffiths WJ, Hornshaw M, Woffendin G, Baker SF, Lockhart A, Heidelberger S, Gustafsson M, Sjövall J, Wang Y. Discovering oxysterols in plasma: a window on the metabolome. Journal of Proteome Research. 7: 3602-12. PMID 18605750 DOI: 10.1021/Pr8001639 |
0.361 |
|
| 2008 |
Griffiths WJ, Wang Y, Karu K, Samuel E, McDonnell S, Hornshaw M, Shackleton C. Potential of sterol analysis by liquid chromatography-tandem mass spectrometry for the prenatal diagnosis of Smith-Lemli-Opitz syndrome. Clinical Chemistry. 54: 1317-24. PMID 18556335 DOI: 10.1373/Clinchem.2007.100644 |
0.325 |
|
| 2008 |
Wang Y, Muneton S, Sjövall J, Jovanovic JN, Griffiths WJ. The effect of 24S-hydroxycholesterol on cholesterol homeostasis in neurons: quantitative changes to the cortical neuron proteome. Journal of Proteome Research. 7: 1606-14. PMID 18303831 DOI: 10.1021/Pr7006076 |
0.338 |
|
| 2008 |
Feltenmark S, Gautam N, Brunnström A, Griffiths W, Backman L, Edenius C, Lindbom L, Björkholm M, Claesson HE. Eoxins are proinflammatory arachidonic acid metabolites produced via the 15-lipoxygenase-1 pathway in human eosinophils and mast cells. Proceedings of the National Academy of Sciences of the United States of America. 105: 680-5. PMID 18184802 DOI: 10.1073/Pnas.0710127105 |
0.325 |
|
| 2008 |
Schumacher M, Liere P, Akwa Y, Rajkowski K, Griffiths W, Bodin K, Sjövall J, Baulieu E. Pregnenolone sulfate in the brain: a controversial neurosteroid. Neurochemistry International. 52: 522-540. PMID 18068870 DOI: 10.1016/J.Neuint.2007.08.022 |
0.37 |
|
| 2008 |
Wang Y, Griffiths WJ. Capillary liquid chromatography combined with tandem mass spectrometry for the study of neurosteroids and oxysterols in brain. Neurochemistry International. 52: 506-21. PMID 17850923 DOI: 10.1016/J.Neuint.2007.07.009 |
0.371 |
|
| 2007 |
Karu K, Hornshaw M, Woffendin G, Bodin K, Hamberg M, Alvelius G, Sjövall J, Turton J, Wang Y, Griffiths WJ. Liquid chromatography-mass spectrometry utilizing multi-stage fragmentation for the identification of oxysterols. Journal of Lipid Research. 48: 976-87. PMID 17251593 DOI: 10.1194/Jlr.M600497-Jlr200 |
0.374 |
|
| 2007 |
Wang Y, Al-Gazzar A, Seibert C, Sharif A, Lane C, Griffiths WJ. Proteomic analysis of cytochromes P450: a mass spectrometry approach. Biochemical Society Transactions. 34: 1246-51. PMID 17073795 DOI: 10.1042/Bst0341246 |
0.327 |
|
| 2006 |
Rai DK, Landin B, Alvelius G, Griffiths WJ. Haemoglobin Södertälje (β118 Phe→Val): A new mutation in human haemoglobin identified by electrospray ionisation mass spectrometry [2] Rapid Communications in Mass Spectrometry. 20: 3481-3482. PMID 17066374 DOI: 10.1002/Rcm.2746 |
0.371 |
|
| 2006 |
Griffiths WJ, Wang Y, Alvelius G, Liu S, Bodin K, Sjövall J. Analysis of oxysterols by electrospray tandem mass spectrometry. Journal of the American Society For Mass Spectrometry. 17: 341-62. PMID 16442307 DOI: 10.1016/J.Jasms.2005.10.012 |
0.375 |
|
| 2006 |
Wang Y, Hornshaw M, Alvelius G, Bodin K, Liu S, Sjövall J, Griffiths WJ. Matrix-assisted laser desorption/ionization high-energy collision-induced dissociation of steroids: analysis of oxysterols in rat brain. Analytical Chemistry. 78: 164-73. PMID 16383324 DOI: 10.1021/Ac051461B |
0.368 |
|
| 2006 |
Khan MA, Wang Y, Heidelberger S, Alvelius G, Liu S, Sjövall J, Griffiths WJ. Analysis of derivatised steroids by matrix-assisted laser desorption/ionisation and post-source decay mass spectrometry. Steroids. 71: 42-53. PMID 16199070 DOI: 10.1016/J.Steroids.2005.08.002 |
0.329 |
|
| 2005 |
Lengqvist J, Mata de Urquiza A, Perlmann T, Sjövall J, Griffiths WJ. Specificity of receptor-ligand interactions and their effect on dimerisation as observed by electrospray mass spectrometry: bile acids form stable adducts to the RXRalpha. Journal of Mass Spectrometry : Jms. 40: 1448-61. PMID 16258897 DOI: 10.1002/Jms.925 |
0.321 |
|
| 2005 |
Lengqvist J, Alvélius G, Jörnvall H, Sjövall J, Perlmann T, Griffiths WJ. Electrospray mass spectrometry for the direct accurate mass measurement of ligands in complex with the retinoid X receptor alpha ligand binding domain. Journal of the American Society For Mass Spectrometry. 16: 1631-40. PMID 16085421 DOI: 10.1016/J.Jasms.2005.06.003 |
0.351 |
|
| 2004 |
Liere P, Pianos A, Eychenne B, Cambourg A, Liu S, Griffiths W, Schumacher M, Sjövall J, Baulieu E. Novel lipoidal derivatives of pregnenolone and dehydroepiandrosterone and absence of their sulfated counterparts in rodent brain Journal of Lipid Research. 45: 2287-2302. PMID 15342680 DOI: 10.1194/Jlr.M400244-Jlr200 |
0.31 |
|
| 2004 |
Tjernberg A, Carnö S, Oliv F, Benkestock K, Edlund PO, Griffiths WJ, Hallén D. Determination of dissociation constants for protein-ligand complexes by electrospray ionization mass spectrometry. Analytical Chemistry. 76: 4325-31. PMID 15283568 DOI: 10.1021/Ac0497914 |
0.339 |
|
| 2004 |
Norberg A, Griffiths WJ, Hjelmqvist L, Jörnvall H, Rökaeus A. Identification of variant forms of the neuroendocrine peptide galanin. Rapid Communications in Mass Spectrometry : Rcm. 18: 1583-91. PMID 15282783 DOI: 10.1002/Rcm.1522 |
0.302 |
|
| 2004 |
Griffiths WJ, Alvelius G, Liu S, Sjövall J. High-energy collision-induced dissociation of oxosteroids derivatised to Girard hydrazones. European Journal of Mass Spectrometry (Chichester, England). 10: 63-88. PMID 15100480 DOI: 10.1255/Ejms.625 |
0.302 |
|
| 2004 |
Lengqvist J, Mata De Urquiza A, Bergman AC, Willson TM, Sjövall J, Perlmann T, Griffiths WJ. Polyunsaturated fatty acids including docosahexaenoic and arachidonic acid bind to the retinoid X receptor alpha ligand-binding domain. Molecular & Cellular Proteomics : McP. 3: 692-703. PMID 15073272 DOI: 10.1074/Mcp.M400003-Mcp200 |
0.309 |
|
| 2004 |
Rai DK, Green BN, Landin B, Alvelius G, Griffiths WJ. Accurate mass measurement and tandem mass spectrometry of intact globin chains identify the low proportion variant hemoglobin Lepore-Boston-Washington from the blood of a heterozygote Journal of Mass Spectrometry. 39: 289-294. PMID 15039936 DOI: 10.1002/Jms.581 |
0.348 |
|
| 2004 |
Nisar S, Lane CS, Wilderspin AF, Welham KJ, Griffiths WJ, Patterson LH. A proteomic approach to the identification of cytochrome P450 isoforms in male and female rat liver by nanoscale liquid chromatography-electrospray ionization-tandem mass spectrometry. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 32: 382-6. PMID 15039290 DOI: 10.1124/Dmd.32.4.382 |
0.322 |
|
| 2004 |
Lengqvist J, Svensson R, Evergren E, Morgenstern R, Griffiths WJ. Observation of an intact noncovalent homotrimer of detergent-solubilized rat microsomal glutathione transferase-1 by electrospray mass spectrometry. The Journal of Biological Chemistry. 279: 13311-6. PMID 14726533 DOI: 10.1074/Jbc.M310958200 |
0.333 |
|
| 2003 |
Liu S, Sjövall J, Griffiths WJ. Neurosteroids in rat brain: extraction, isolation, and analysis by nanoscale liquid chromatography-electrospray mass spectrometry. Analytical Chemistry. 75: 5835-46. PMID 14588024 DOI: 10.1021/Ac0346297 |
0.362 |
|
| 2003 |
Griffiths WJ. Tandem mass spectrometry in the study of fatty acids, bile acids, and steroids. Mass Spectrometry Reviews. 22: 81-152. PMID 12820273 DOI: 10.1002/Mas.10046 |
0.375 |
|
| 2003 |
Rai DK, Griffiths WJ, Landin B, Wild BJ, Alvelius G, Green BN. Accurate mass measurement by electrospray ionization quadrupole mass spectrometry: Detection of variants differing by <6 Da from normal in human hemoglobin heterozygotes Analytical Chemistry. 75: 1978-1982. PMID 12720330 DOI: 10.1021/Ac026228H |
0.334 |
|
| 2003 |
Griffiths WJ, Liu S, Alvelius G, Sjövall J. Derivatisation for the characterisation of neutral oxosteroids by electrospray and matrix-assisted laser desorption/ionisation tandem mass spectrometry: the Girard P derivative. Rapid Communications in Mass Spectrometry : Rcm. 17: 924-35. PMID 12717765 DOI: 10.1002/Rcm.1002 |
0.349 |
|
| 2003 |
Liu S, Griffiths WJ, Sjövall J. Capillary liquid chromatography/electrospray mass spectrometry for analysis of steroid sulfates in biological samples. Analytical Chemistry. 75: 791-7. PMID 12622368 DOI: 10.1021/Ac0262154 |
0.305 |
|
| 2002 |
Rai DK, Landin B, Griffiths WJ, Alvelius G. Identification of N-terminal acetylation in Hb Raleigh (β1Val →Ac-Ala) by electrospray tandem mass spectrometry Rapid Communications in Mass Spectrometry. 16: 1793-1796. PMID 12207369 DOI: 10.1002/Rcm.774 |
0.325 |
|
| 2002 |
Rai DK, Landin B, Alvelius G, Griffiths WJ. Electrospray tandem mass spectrometry of intact β-chain hemoglobin variants Analytical Chemistry. 74: 2097-2102. PMID 12033312 DOI: 10.1021/Ac011068F |
0.346 |
|
| 2002 |
Wang Y, Griffiths WJ, Jörnvall H, Agerberth B, Johansson J. Antibacterial peptides in stimulated human granulocytes: characterization of ubiquitinated histone H1A. European Journal of Biochemistry / Febs. 269: 512-8. PMID 11856309 DOI: 10.1046/J.0014-2956.2001.02675.X |
0.318 |
|
| 2002 |
Rai DK, Landin B, Griffiths WJ, Alvelius G, Green BN. Characterization of the elusive disulfide bridge forming human Hb variant:Hb Ta-Li β83 (EF7)Gly → Cysby electrospray mass spectrometry Journal of the American Society For Mass Spectrometry. 13: 187-191. PMID 11838022 DOI: 10.1016/S1044-0305(01)00349-X |
0.344 |
|
| 2001 |
Stark M, Danielsson O, Griffiths WJ, Jörnvall H, Johansson J. Peptide repertoire of human cerebrospinal fluid: novel proteolytic fragments of neuroendocrine proteins. Journal of Chromatography B: Biomedical Sciences and Applications. 754: 357-367. PMID 11339279 DOI: 10.1016/S0378-4347(00)00628-9 |
0.323 |
|
| 2001 |
Griffiths WJ, Jonsson AP, Liu S, Rai DK, Wang Y. Electrospray and tandem mass spectrometry in biochemistry. Biochemical Journal. 355: 545-561. PMID 11311115 DOI: 10.1042/Bj3550545 |
0.366 |
|
| 2001 |
Wang Y, Johansson J, Griffiths WJ. Characterisation of variant forms of prophenin: mechanistic aspects of the fragmentation of proline-rich peptides. Rapid Communications in Mass Spectrometry : Rcm. 14: 2182-202. PMID 11114029 DOI: 10.1002/1097-0231(20001215)14:23<2182::Aid-Rcm151>3.0.Co;2-7 |
0.311 |
|
| 2001 |
Yang Y, Griffiths WJ, Nordling M, Nygren J, Möller L, Bergman J, Liepinsh E, Otting G, Gustafsson JA, Rafter J, Sjövall J. Ring opening of benzo[a]pyrene in the germ-free rat is a novel pathway for formation of potentially genotoxic metabolites. Biochemistry. 39: 15585-91. PMID 11112546 DOI: 10.1021/Bi001148Y |
0.351 |
|
| 2001 |
Griffiths WJ, Jonsson AP. Gas-Phase Conformation Can Have an Influence on Peptide Fragmentation European Journal of Mass Spectrometry. 7: 89-99. DOI: 10.1255/Ejms.394 |
0.353 |
|
| 2001 |
Rai DK, Griffiths WJ, Alvelius G, Landin B. Electrospray Mass Spectrometry: An Efficient Method to Detect Silent Hemoglobin Variants Causing Erythrocytosis Clinical Chemistry. 47: 1308-1311. DOI: 10.1093/Clinchem/47.7.1308 |
0.323 |
|
| 2000 |
Urquiza AMd, Liu S, Sjöberg M, Zetterström RH, Griffiths W, Sjövall J, Perlmann T. Docosahexaenoic Acid, a Ligand for the Retinoid X Receptor in Mouse Brain Science. 290: 2140-2144. PMID 11118147 DOI: 10.1126/Science.290.5499.2140 |
0.312 |
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| 2000 |
Lindh I, Hjelmqvist L, Bergman T, Sjövall J, Griffiths WJ. De novo sequencing of proteolytic peptides by a combination of C-terminal derivatization and nano-electrospray/collision-induced dissociation mass spectrometry Journal of the American Society For Mass Spectrometry. 11: 673-686. PMID 10937790 DOI: 10.1016/S1044-0305(00)00138-0 |
0.318 |
|
| 2000 |
Rai DK, Alvelius G, Landin B, Griffiths WJ. Electrospray tandem mass spectrometry in the rapid identification of ?-chain haemoglobin variants Rapid Communications in Mass Spectrometry. 14: 1184-1194. PMID 10918366 DOI: 10.1002/1097-0231(20000730)14:14<1184::Aid-Rcm7>3.0.Co;2-S |
0.323 |
|
| 2000 |
Jonsson AP, Griffiths WJ, Bratt P, Johansson I, Strömberg N, Jörnvall H, Bergman T. A novel Ser O-glucuronidation in acidic proline-rich proteins identified by tandem mass spectrometry. Febs Letters. 475: 131-134. PMID 10858503 DOI: 10.1016/S0014-5793(00)01645-8 |
0.344 |
|
| 2000 |
Liu S, Sjövall J, Griffiths WJ. Analysis of oxosteroids by nano-electrospray mass spectrometry of their oximes. Rapid Communications in Mass Spectrometry : Rcm. 14: 390-400. PMID 10717647 DOI: 10.1002/(Sici)1097-0231(20000331)14:6<390::Aid-Rcm882>3.0.Co;2-7 |
0.332 |
|
| 2000 |
Yang Y, Griffiths WJ, Midtvedt T, Sjövall J, Rafter J, Gustafsson JA. Characterization of conjugated metabolites of benzo[a]pyrene in germ-free rat urine by liquid chromatography/electrospray tandem mass spectrometry. Chemical Research in Toxicology. 12: 1182-9. PMID 10604867 DOI: 10.1021/Tx990101E |
0.324 |
|
| 1999 |
Jonsson AP, Carlquist M, Husman B, Ljunggren J, Jörnvall H, Bergman T, Griffiths WJ. Structural analysis of the thyroid hormone receptor ligand binding domain: studies using a quadrupole time-of-flight tandem mass spectrometer. Rapid Communications in Mass Spectrometry : Rcm. 13: 1782-91. PMID 10482889 DOI: 10.1002/(Sici)1097-0231(19990930)13:18<1782::Aid-Rcm714>3.0.Co;2-W |
0.356 |
|
| 1999 |
Griffiths WJ, Liu S, Yang Y, Purdy RH, Sjövall J. Nano-electrospray tandem mass spectrometry for the analysis of neurosteroid sulphates. Rapid Communications in Mass Spectrometry. 13: 1595-1610. PMID 10421902 DOI: 10.1002/(Sici)1097-0231(19990815)13:15<1595::Aid-Rcm681>3.0.Co;2-1 |
0.355 |
|
| 1998 |
Hamberg M, Liepinsh E, Otting G, Griffiths W. Isolation And Structure Of A New Galactolipid From Oat Seeds Lipids. 33: 355-363. PMID 9590622 DOI: 10.1007/S11745-998-0215-9 |
0.318 |
|
| 1998 |
Yang Y, Rafter J, Gustafsson JA, Sjövall J, Griffiths WJ. Analysis of the major mercapturic acid pathway metabolites of benzo[a]pyrene found in rat urine by nano-electrospray mass spectrometry. Rapid Communications in Mass Spectrometry : Rcm. 12: 465-71. PMID 9586234 DOI: 10.1002/(Sici)1097-0231(19980430)12:8<465::Aid-Rcm180>3.0.Co;2-F |
0.372 |
|
| 1998 |
Lindh I, Sjövall J, Bergman T, Griffiths WJ. Negative-ion electrospray tandem mass spectrometry of peptides derivatized with 4-aminonaphthalenesulphonic acid Journal of Mass Spectrometry. 33: 988-993. DOI: 10.1002/(Sici)1096-9888(1998100)33:10<988::Aid-Jms713>3.0.Co;2-S |
0.332 |
|
| 1997 |
Hjertman M, Wejde J, Dricu A, Carlberg M, Griffiths WJ, Sjövall J, Larsson O. Evidence for protein dolichylation. Febs Letters. 416: 235-8. PMID 9373159 DOI: 10.1016/S0014-5793(97)01208-8 |
0.306 |
|
| 1997 |
Yang Y, Griffiths WJ, Nazer H, Sjövall J. Analysis of bile acids and bile alcohols in urine by capillary column liquid chromatography-mass spectrometry using fast atom bombardment or electrospray ionization and collision-induced dissociation. Biomedical Chromatography : Bmc. 11: 240-55. PMID 9257002 DOI: 10.1002/(Sici)1099-0801(199707)11:4<240::Aid-Bmc686>3.0.Co;2-6 |
0.367 |
|
| 1997 |
Yang Y, Rafter J, Gustafsson JÅ, Sjövall J, Griffiths W. Letter: Differentiation of isomeric mercapturic acid pathway metabolites of benzo[a]pyrene European Journal of Mass Spectrometry. 3: 396. DOI: 10.1255/Ejms.172 |
0.331 |
|
| 1997 |
Yang Y, Griffiths WJ, Sjövall J, Gustafsson J, Rafter J. Liquid chromatography-mass spectrometry with collision-induced dissociation of conjugated metabolites of benzol[a]pyrene Journal of the American Society For Mass Spectrometry. 8: 50-61. DOI: 10.1016/S1044-0305(96)00136-5 |
0.351 |
|
| 1997 |
Lindh I, Griffiths WJ, Bergman T, Sjövall J. Electrospray/collision-induced dissociation of derivatised peptides: studies on a hybrid magnetic sector–orthogonal time-of-flight mass spectrometer International Journal of Mass Spectrometry and Ion Processes. 164: 71-79. DOI: 10.1016/S0168-1176(97)00052-9 |
0.322 |
|
| 1997 |
Zhang J, Griffiths WJ, Sjövall J. The synthesis of taurine-conjugated bile acids and bile acid sulfates labeled with 14C or 3H in the taurine moiety Journal of Labelled Compounds and Radiopharmaceuticals. 39: 159-164. DOI: 10.1002/(Sici)1099-1344(199702)39:2<159::Aid-Jlcr954>3.0.Co;2-W |
0.306 |
|
| 1997 |
Griffiths WJ, Hjertman M, Wejde J, Larsson O, Sjövall J. Tandem Mass Spectrometry of Geranylgeranylcysteine Journal of Mass Spectrometry. 32: 899-903. DOI: 10.1002/(Sici)1096-9888(199708)32:8<899::Aid-Jms543>3.0.Co;2-6 |
0.332 |
|
| 1996 |
Griffiths WJ, Yang Y, Sjövall J, Lindgren JA. Electrospray/collision-induced dissociation mass spectrometry of mono-, di- and tri-hydroxylated lipoxygenase products, including leukotrienes of the B-series and lipoxins Rapid Communications in Mass Spectrometry. 10: 183-196. PMID 8616266 DOI: 10.1002/(Sici)1097-0231(19960131)10:2<183::Aid-Rcm456>3.0.Co;2-W |
0.339 |
|
| 1996 |
Griffiths WJ, Brown A, Reimendal R, Yang Y, Zhang J, Sjövall J. A Comparison of Fast-atom Bombardment and Electrospray as Methods of Ionization in the Study of Sulphated- and Sulphonated-lipids by Tandem Mass Spectrometry Rapid Communications in Mass Spectrometry. 10: 1169-1174. DOI: 10.1002/(Sici)1097-0231(19960731)10:10<1169::Aid-Rcm632>3.0.Co;2-M |
0.352 |
|
| 1996 |
Griffiths WJ, Yang Y, Sjövall J, Lindgren JÅ. Electrospray Tandem Mass Spectrometry of Cysteinyl Leukotrienes Rapid Communications in Mass Spectrometry. 10: 1054-1070. DOI: 10.1002/(Sici)1097-0231(19960715)10:9<1054::Aid-Rcm558>3.0.Co;2-T |
0.339 |
|
| 1996 |
Griffiths WJ, Hjertman M, Lundsjö A, Wejde J, Sjövall J, Larsson O. Analysis of Dolichols and Polyprenols and Their Derivatives by Electron Impact, Fast Atom Bombardment and Electrospray Ionization Tandem Mass Spectrometry Rapid Communications in Mass Spectrometry. 10: 663-675. DOI: 10.1002/(Sici)1097-0231(199604)10:6<663::Aid-Rcm523>3.0.Co;2-N |
0.359 |
|
| 1995 |
Lindh I, Griffiths WJ, Bergman T, Sjövall J. Charge-remote fragmentation of peptides derivatized with 4-aminonaphthalenesulphonic acid. Rapid Communications in Mass Spectrometry : Rcm. 8: 797-803. PMID 8000077 DOI: 10.1002/Rcm.1290081002 |
0.306 |
|
| 1995 |
Pettersson T, Ernström U, Griffiths W, Sjövall J, Bergman T, Jörnvall H. Lutein associated with a transthyretin indicates carotenoid derivation and novel multiplicity of transthyretin ligands. Febs Letters. 365: 23-6. PMID 7774708 DOI: 10.1016/0014-5793(95)00389-Q |
0.306 |
|
| 1995 |
Yang Y, Griffiths WJ, Lindgren JA, Sjövall J. Liquid chromatography/mass spectrometry with collision-induced dissociation of arachidonic acid metabolites derivatized with aminobenzenesulphonic acid Rapid Communications in Mass Spectrometry : Rcm. 9: 289-299. PMID 7756703 DOI: 10.1002/Rcm.1290090407 |
0.364 |
|
| 1995 |
Griffiths WJ, Lindh I, Bergman T, Sjövall J. Negative-ion electrospray mass spectra of peptides derivatized with 4-aminonaphthalenesulphonic acid Rapid Communications in Mass Spectrometry. 9: 667-676. DOI: 10.1002/Rcm.1290090809 |
0.318 |
|
| 1994 |
Marschall H, Griffiths WJ, Götze U, Zhang J, Wietholtz H, Busch N, Sjövall J, Matern S. The major metabolites of ursodeoxycholic acid in human urine are conjugated with N-acetylglucosamine Hepatology. 20: 845-853. PMID 7927225 DOI: 10.1002/Hep.1840200412 |
0.319 |
|
| 1994 |
Griffiths WJ, Zhang J, Sjövall J. Charge-remote fragmentation of sulphated and glucuronidated bile acids and their 2-aminoethanesulphonic acid derivatives Rapid Communications in Mass Spectrometry. 8: 227-236. DOI: 10.1002/Rcm.1290080302 |
0.35 |
|
| 1993 |
Griffiths WJ, Zhang J, Sjövall J. Charge-remote fragmentation of bile acids derivatized with amino-sulphonic acids Rapid Communications in Mass Spectrometry. 7: 235-240. DOI: 10.1002/Rcm.1290070314 |
0.336 |
|
| 1992 |
Griffiths WJ, Egestad B, Sjövall J. Charge-remote fragmentation of taurine-conjugated bile acids. Rapid Communications in Mass Spectrometry : Rcm. 5: 391-4. PMID 1841653 DOI: 10.1002/Rcm.1290050904 |
0.328 |
|
| 1991 |
Johnson LBN, Griffiths WJ, Roberts EV, Lam LKP, Vederas JC, Reid CJ, Ballantine JA. A mass spectral analysis of some cucurbitacins isolated from Fevillea cordifolia Journal of the Chemical Society-Perkin Transactions 1. 10: 2583-2588. DOI: 10.1039/P19910002583 |
0.309 |
|
| 1986 |
MULLINS CJ, WALTON TJ, NEWTON RP, BEYNON JH, BRENTON AG, GRIFFITHS WJ. The identification of δ-tocopherol in cyanobacteria using mass-analysed ion-kinetic energy spectroscopy Biochemical Society Transactions. 14: 969-970. DOI: 10.1042/Bst0140969 |
0.317 |
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