Ernest Arenas - Publications

Affiliations: 
Karolinska Institute, Stockholm, Sweden 
Area:
Stem cells, dopamine neurons, Wnts

182 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Sif Ásgrímsdóttir E, Arenas E. Generation of a fluorescent hESC reporter line (Kle033-A-1) for the isolation of distinct midbrain progenitor cell types. Stem Cell Research. 81: 103523. PMID 39383604 DOI: 10.1016/j.scr.2024.103523  0.319
2023 Siletti K, Hodge R, Mossi Albiach A, Lee KW, Ding SL, Hu L, Lönnerberg P, Bakken T, Casper T, Clark M, Dee N, Gloe J, Hirschstein D, Shapovalova NV, Keene CD, ... ... Arenas E, et al. Transcriptomic diversity of cell types across the adult human brain. Science (New York, N.Y.). 382: eadd7046. PMID 37824663 DOI: 10.1126/science.add7046  0.598
2023 Braun E, Danan-Gotthold M, Borm LE, Lee KW, Vinsland E, Lönnerberg P, Hu L, Li X, He X, Andrusivová Ž, Lundeberg J, Barker RA, Arenas E, Sundström E, Linnarsson S. Comprehensive cell atlas of the first-trimester developing human brain. Science (New York, N.Y.). 382: eadf1226. PMID 37824650 DOI: 10.1126/science.adf1226  0.673
2023 Nishimura K, Ásgrímsdóttir ES, Yang S, Arenas E. A protocol for the differentiation of human embryonic stem cells into midbrain dopaminergic neurons. Star Protocols. 4: 102355. PMID 37310863 DOI: 10.1016/j.xpro.2023.102355  0.838
2022 Conforti P, Bocchi VD, Campus I, Scaramuzza L, Galimberti M, Lischetti T, Talpo F, Pedrazzoli M, Murgia A, Ferrari I, Cordiglieri C, Fasciani A, Arenas E, Felsenfeld D, Biella G, et al. -derived medium spiny neurons recapitulate human striatal development and complexity at single-cell resolution. Cell Reports Methods. 2: 100367. PMID 36590694 DOI: 10.1016/j.crmeth.2022.100367  0.379
2022 Nishimura K, Yang S, Lee KW, Ásgrímsdóttir ES, Nikouei K, Paslawski W, Gnodde S, Lyu G, Hu L, Saltó C, Svenningsson P, Hjerling-Leffler J, Linnarsson S, Arenas E. Single-cell transcriptomics reveals correct developmental dynamics and high-quality midbrain cell types by improved hESC differentiation. Stem Cell Reports. PMID 36400027 DOI: 10.1016/j.stemcr.2022.10.016  0.834
2022 Kaiser K, Jang A, Kompanikova P, Lun MP, Prochazka J, Machon O, Dani N, Prochazkova M, Laurent B, Gyllborg D, van Amerongen R, Fame RM, Gupta S, Wu F, Barker RA, ... ... Arenas E, et al. Correction: MEIS-WNT5A axis regulates development of fourth ventricle choroid plexus. Development (Cambridge, England). 149. PMID 35119069 DOI: 10.1242/dev.200517  0.783
2021 Ahmed M, Owens MJS, Toledo EM, Arenas E, Bradley M, Ffrench-Constant C. Combinatorial ECM Arrays Identify Cooperative Roles for Matricellular Proteins in Enhancing the Generation of TH+ Neurons From Human Pluripotent Cells. Frontiers in Cell and Developmental Biology. 9: 755406. PMID 34926447 DOI: 10.3389/fcell.2021.755406  0.762
2021 Griffiths WJ, Abdel-Khalik J, Moore SF, Wijeyekoon RS, Crick PJ, Yutuc E, Farrell K, Breen DP, Williams-Gray CH, Theofilopoulos S, Arenas E, Trupp M, Barker RA, Wang Y. The Cerebrospinal Fluid Profile of Cholesterol Metabolites in Parkinson's Disease and Their Association With Disease State and Clinical Features. Frontiers in Aging Neuroscience. 13: 685594. PMID 34526889 DOI: 10.3389/fnagi.2021.685594  0.769
2021 Kaiser K, Jang A, Kompanikova P, Lun MP, Prochazka J, Machon O, Dani N, Prochazkova M, Laurent B, Gyllborg D, van Amerongen R, Fame RM, Gupta S, Wu F, Barker RA, ... ... Arenas E, et al. MEIS-WNT5A axis regulates development of fourth ventricle choroid plexus. Development (Cambridge, England). 148. PMID 34032267 DOI: 10.1242/dev.192054  0.807
2020 Ásgrímsdóttir ES, Arenas E. Midbrain Dopaminergic Neuron Development at the Single Cell Level: and in Stem Cells. Frontiers in Cell and Developmental Biology. 8: 463. PMID 32733875 DOI: 10.3389/Fcell.2020.00463  0.492
2020 Arenas E. Method to combat Parkinson's disease by astrocyte-to-neuron conversion. Nature. 582: 489-490. PMID 32581373 DOI: 10.1038/D41586-020-01817-4  0.445
2020 Toledo EM, Yang S, Gyllborg D, van Wijk KE, Sinha I, Varas-Godoy M, Grigsby CL, Lönnerberg P, Islam S, Steffensen KR, Linnarsson S, Arenas E. Srebf1 Controls Midbrain Dopaminergic Neurogenesis. Cell Reports. 31: 107601. PMID 32375051 DOI: 10.1016/J.Celrep.2020.107601  0.795
2020 Bryois J, Skene NG, Hansen TF, Kogelman LJA, Watson HJ, Liu Z, Brueggeman L, Breen G, Bulik CM, Arenas E, Hjerling-Leffler J, Sullivan PF. Genetic identification of cell types underlying brain complex traits yields insights into the etiology of Parkinson's disease. Nature Genetics. PMID 32341526 DOI: 10.1038/S41588-020-0610-9  0.704
2019 Ahmed M, Marziali LN, Arenas E, Feltri ML, Ffrench-Constant C. Laminin α2 controls mouse and human stem cell behaviour during midbrain dopaminergic neuron development. Development (Cambridge, England). PMID 31371375 DOI: 10.1242/Dev.172668  0.487
2019 Meljon A, Crick PJ, Yutuc E, Yau JL, Seckl JR, Theofilopoulos S, Arenas E, Wang Y, Griffiths WJ. Mining for Oxysterols in Mouse Brain and Plasma: Relevance to Spastic Paraplegia Type 5. Biomolecules. 9. PMID 31013940 DOI: 10.3390/biom9040149  0.776
2019 Kaiser K, Gyllborg D, Procházka J, Salašová A, Kompaníková P, Molina FL, Laguna-Goya R, Radaszkiewicz T, Harnoš J, Procházková M, Potěšil D, Barker RA, Casado ÁG, Zdráhal Z, Sedláček R, ... Arenas E, et al. WNT5A is transported via lipoprotein particles in the cerebrospinal fluid to regulate hindbrain morphogenesis. Nature Communications. 10: 1498. PMID 30940800 DOI: 10.1038/S41467-019-09298-4  0.781
2019 Rebellato P, Kaczynska D, Kanatani S, Rayyes IA, Zhang S, Villaescusa C, Falk A, Arenas E, Hermanson O, Louhivuori L, Uhlén P. The T-type Ca Channel Ca3.2 Regulates Differentiation of Neural Progenitor Cells During Cortical Development via Caspase-3. Neuroscience. PMID 30677486 DOI: 10.1016/J.Neuroscience.2019.01.015  0.757
2019 Theofilopoulos S, Abreu de Oliveira WA, Yang S, Yutuc E, Saeed A, Abdel-Khalik J, Ullgren A, Cedazo-Minguez A, Björkhem I, Wang Y, Griffiths WJ, Arenas E. 24(),25-Epoxycholesterol and () overexpression promote midbrain dopaminergic neurogenesis . The Journal of Biological Chemistry. PMID 30655290 DOI: 10.1074/Jbc.Ra118.005639  0.83
2018 Griffiths WJ, Crick PJ, Meljon A, Theofilopoulos S, Abdel-Khalik J, Yutuc E, Parker JE, Kelly DE, Kelly SL, Arenas E, Wang Y. Additional pathways of sterol metabolism: Evidence from analysis of Cyp27a1-/- mouse brain and plasma. Biochimica Et Biophysica Acta. Molecular and Cell Biology of Lipids. PMID 30471425 DOI: 10.1016/J.Bbalip.2018.11.006  0.8
2018 Tanaka N, Katayama S, Reddy A, Nishimura K, Niwa N, Hongo H, Ogihara K, Kosaka T, Mizuno R, Kikuchi E, Mikami S, Miyakawa A, Arenas E, Kere J, Oya M, et al. Single-cell RNA-seq analysis reveals the platinum resistance gene COX7B and the surrogate marker CD63. Cancer Medicine. PMID 30367559 DOI: 10.1002/Cam4.1828  0.749
2018 Yang S, Toledo EM, Rosmaninho P, Peng C, Uhlén P, Castro DS, Arenas E. A Zeb2-miR-200c loop controls midbrain dopaminergic neuron neurogenesis and migration. Communications Biology. 1: 75. PMID 30271956 DOI: 10.1038/s42003-018-0080-0  0.829
2018 Gyllborg D, Ahmed M, Toledo EM, Theofilopoulos S, Yang S, Ffrench-Constant C, Arenas E. The Matricellular Protein R-Spondin 2 Promotes Midbrain Dopaminergic Neurogenesis and Differentiation. Stem Cell Reports. PMID 30146491 DOI: 10.1016/J.Stemcr.2018.07.014  0.835
2018 Zeisel A, Hochgerner H, Lönnerberg P, Johnsson A, Memic F, van der Zwan J, Häring M, Braun E, Borm LE, La Manno G, Codeluppi S, Furlan A, Lee K, Skene N, Harris KD, ... ... Arenas E, et al. Molecular Architecture of the Mouse Nervous System. Cell. 174: 999-1014.e22. PMID 30096314 DOI: 10.1016/J.Cell.2018.06.021  0.817
2018 Okawa S, Saltó C, Ravichandran S, Yang S, Toledo EM, Arenas E, Del Sol A. Transcriptional synergy as an emergent property defining cell subpopulation identity enables population shift. Nature Communications. 9: 2595. PMID 29968757 DOI: 10.1038/S41467-018-05016-8  0.812
2017 Zhang D, Yang S, Toledo EM, Gyllborg D, Saltó C, Carlos Villaescusa J, Arenas E. Niche-derived laminin-511 promotes midbrain dopaminergic neuron survival and differentiation through YAP. Science Signaling. 10. PMID 28831020 DOI: 10.1126/Scisignal.Aal4165  0.842
2017 Kitambi SS, Toledo EM, Usoskin D, Wee S, Harisankar A, Svensson R, Sigmundsson K, Kalderén C, Niklasson M, Kundu S, Aranda S, Westermark B, Uhrbom L, Andäng M, Damberg P, ... ... Arenas E, et al. Retraction Notice to: Vulnerability of Glioblastoma Cells to Catastrophic Vacuolization and Death Induced by a Small Molecule. Cell. 170: 407. PMID 28709005 DOI: 10.1016/j.cell.2017.06.044  0.775
2017 Salašová A, Yokota C, Potěšil D, Zdráhal Z, Bryja V, Arenas E. A proteomic analysis of LRRK2 binding partners reveals interactions with multiple signaling components of the WNT/PCP pathway. Molecular Neurodegeneration. 12: 54. PMID 28697798 DOI: 10.1186/S13024-017-0193-9  0.638
2017 Strakova K, Matricon P, Yokota C, Arthofer E, Bernatik O, Rodriguez D, Arenas E, Carlsson J, Bryja V, Schulte G. The tyrosine Y250(2.39) in Frizzled 4 defines a conserved motif important for structural integrity of the receptor and recruitment of Disheveled. Cellular Signalling. PMID 28668722 DOI: 10.1016/J.Cellsig.2017.06.018  0.712
2017 Toledo EM, Gyllborg D, Arenas E. Translation of WNT developmental programs into stem cell replacement strategies for the treatment of Parkinson's disease. British Journal of Pharmacology. PMID 28547771 DOI: 10.1111/Bph.13871  0.836
2017 Hörtenhuber M, Toledo EM, Smedler E, Arenas E, Malmersjö S, Louhivuori L, Uhlén P. Mapping Genes for Calcium Signaling and Their Associated Human Genetic Disorders. Bioinformatics (Oxford, England). PMID 28430858 DOI: 10.1093/Bioinformatics/Btx225  0.765
2017 Kaucka M, Zikmund T, Tesarova M, Gyllborg D, Hellander A, Jaros J, Kaiser J, Petersen J, Szarowska B, Newton PT, Dyachuk V, Li L, Qian H, Johansson AS, Mishina Y, ... ... Arenas E, et al. Oriented clonal cell dynamics enables accurate growth and shaping of vertebrate cartilage. Elife. 6. PMID 28414273 DOI: 10.7554/Elife.25902  0.771
2017 di Val Cervo PR, Romanov RA, Spigolon G, Masini D, Martín-Montañez E, Toledo EM, La Manno G, Feyder M, Pifl C, Ng YH, Sánchez SP, Linnarsson S, Wernig M, Harkany T, Fisone G, ... Arenas E, et al. Induction of functional dopamine neurons from human astrocytes in vitro and mouse astrocytes in a Parkinson's disease model. Nature Biotechnology. PMID 28398344 DOI: 10.1038/Nbt.3835  0.831
2017 Kaucka M, Zikmund T, Tesarova M, Gyllborg D, Hellander A, Jaros J, Kaiser J, Petersen J, Szarowska B, Newton PT, Dyachuk V, Li L, Qian H, Johansson A, Mishina Y, ... ... Arenas E, et al. Author response: Oriented clonal cell dynamics enables accurate growth and shaping of vertebrate cartilage Elife. DOI: 10.7554/Elife.25902.028  0.772
2016 La Manno G, Gyllborg D, Codeluppi S, Nishimura K, Salto C, Zeisel A, Borm LE, Stott SR, Toledo EM, Villaescusa JC, Lönnerberg P, Ryge J, Barker RA, Arenas E, Linnarsson S. Molecular Diversity of Midbrain Development in Mouse, Human, and Stem Cells. Cell. 167: 566-580.e19. PMID 27716510 DOI: 10.1016/J.Cell.2016.09.027  0.832
2016 Kaucka M, Ivashkin E, Gyllborg D, Zikmund T, Tesarova M, Kaiser J, Xie M, Petersen J, Pachnis V, Nicolis SK, Yu T, Sharpe P, Arenas E, Brismar H, Blom H, et al. Analysis of neural crest-derived clones reveals novel aspects of facial development. Science Advances. 2: e1600060. PMID 27493992 DOI: 10.1126/Sciadv.1600060  0.798
2016 Villaescusa JC, Li B, Toledo EM, Rivetti di Val Cervo P, Yang S, Stott SR, Kaiser K, Islam S, Gyllborg D, Laguna-Goya R, Landreh M, Lönnerberg P, Falk A, Bergman T, Barker RA, ... ... Arenas E, et al. A PBX1 transcriptional network controls dopaminergic neuron development and is impaired in Parkinson's disease. The Embo Journal. PMID 27354364 DOI: 10.15252/Embj.201593725  0.815
2016 Marques S, Zeisel A, Codeluppi S, van Bruggen D, Mendanha Falcão A, Xiao L, Li H, Häring M, Hochgerner H, Romanov RA, Gyllborg D, Muñoz-Manchado AB, La Manno G, Lönnerberg P, Floriddia EM, ... ... Arenas E, et al. Oligodendrocyte heterogeneity in the mouse juvenile and adult central nervous system. Science (New York, N.Y.). 352: 1326-9. PMID 27284195 DOI: 10.1126/Science.Aaf6463  0.785
2016 Hedlund E, Belnoue L, Theofilopoulos S, Salto C, Bye C, Parish C, Deng Q, Kadkhodaei B, Ericson J, Arenas E, Perlmann T, Simon A. Dopamine Receptor Antagonists Enhance Proliferation and Neurogenesis of Midbrain Lmx1a-expressing Progenitors. Scientific Reports. 6: 26448. PMID 27246266 DOI: 10.1038/Srep26448  0.816
2016 Månsson-Broberg A, Rodin S, Bulatovic I, Ibarra C, Löfling M, Genead R, Wärdell E, Felldin U, Granath C, Alici E, Le Blanc K, Smith CI, Salašová A, Westgren M, Sundström E, ... ... Arenas E, et al. Wnt/β-Catenin Stimulation and Laminins Support Cardiovascular Cell Progenitor Expansion from Human Fetal Cardiac Mesenchymal Stromal Cells. Stem Cell Reports. PMID 27052314 DOI: 10.1016/J.Stemcr.2016.02.014  0.657
2015 Arenas E, Saltó C, Villaescusa C. WNT signaling in midbrain dopaminergic neuron development and cell replacement therapies for Parkinson's disease. Springerplus. 4: L49. PMID 27386211 DOI: 10.1186/2193-1801-4-S1-L49  0.523
2015 Fukusumi Y, Meier F, Götz S, Matheus F, Irmler M, Beckervordersandforth R, Faus-Kessler T, Minina E, Rauser B, Zhang J, Arenas E, Andersson E, Niehrs C, Beckers J, Simeone A, et al. Dickkopf 3 Promotes the Differentiation of a Rostrolateral Midbrain Dopaminergic Neuronal Subset In Vivo and from Pluripotent Stem Cells In Vitro in the Mouse. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 13385-401. PMID 26424886 DOI: 10.1523/Jneurosci.1722-15.2015  0.765
2015 Theofilopoulos S, Arenas E. Liver X receptors and cholesterol metabolism: role in ventral midbrain development and neurodegeneration. F1000prime Reports. 7: 37. PMID 26097711 DOI: 10.12703/P7-37  0.809
2015 Arenas E, Denham M, Villaescusa JC. How to make a midbrain dopaminergic neuron. Development (Cambridge, England). 142: 1918-36. PMID 26015536 DOI: 10.1242/Dev.097394  0.831
2014 Theofilopoulos S, Griffiths WJ, Crick PJ, Yang S, Meljon A, Ogundare M, Kitambi SS, Lockhart A, Tuschl K, Clayton PT, Morris AA, Martinez A, Reddy MA, Martinuzzi A, Bassi MT, ... ... Arenas E, et al. Cholestenoic acids regulate motor neuron survival via liver X receptors. The Journal of Clinical Investigation. 124: 4829-42. PMID 25271621 DOI: 10.1172/Jci68506  0.792
2014 Kitambi SS, Toledo EM, Usoskin D, Wee S, Harisankar A, Svensson R, Sigmundsson K, Kalderén C, Niklasson M, Kundu S, Aranda S, Westermark B, Uhrbom L, Andäng M, Damberg P, ... ... Arenas E, et al. Vulnerability of glioblastoma cells to catastrophic vacuolization and death induced by a small molecule. Cell. 157: 313-28. PMID 24656405 DOI: 10.1016/J.Cell.2014.02.021  0.793
2014 Arenas E. Wnt signaling in midbrain dopaminergic neuron development and regenerative medicine for Parkinson's disease. Journal of Molecular Cell Biology. 6: 42-53. PMID 24431302 DOI: 10.1093/Jmcb/Mju001  0.503
2013 Pereira SL, Grãos M, Rodrigues AS, Anjo SI, Carvalho RA, Oliveira PJ, Arenas E, Ramalho-Santos J. Inhibition of mitochondrial complex III blocks neuronal differentiation and maintains embryonic stem cell pluripotency. Plos One. 8: e82095. PMID 24312632 DOI: 10.1371/Journal.Pone.0082095  0.458
2013 Yang S, Edman LC, Sánchez-Alcañiz JA, Fritz N, Bonilla S, Hecht J, Uhlén P, Pleasure SJ, Villaescusa JC, Marín O, Arenas E. Cxcl12/Cxcr4 signaling controls the migration and process orientation of A9-A10 dopaminergic neurons. Development (Cambridge, England). 140: 4554-64. PMID 24154522 DOI: 10.1242/Jcs.145136  0.825
2013 Malmersjö S, Rebellato P, Smedler E, Planert H, Kanatani S, Liste I, Nanou E, Sunner H, Abdelhady S, Zhang S, Andäng M, El Manira A, Silberberg G, Arenas E, Uhlén P. Neural progenitors organize in small-world networks to promote cell proliferation. Proceedings of the National Academy of Sciences of the United States of America. 110: E1524-32. PMID 23576737 DOI: 10.1073/Pnas.1220179110  0.665
2013 Andersson ER, Saltó C, Villaescusa JC, Cajanek L, Yang S, Bryjova L, Nagy II, Vainio SJ, Ramirez C, Bryja V, Arenas E. Wnt5a cooperates with canonical Wnts to generate midbrain dopaminergic neurons in vivo and in stem cells. Proceedings of the National Academy of Sciences of the United States of America. 110: E602-10. PMID 23324743 DOI: 10.1073/Pnas.1208524110  0.851
2013 González P, Fernández-Martos CM, Arenas E, Rodríguez FJ. The Ryk receptor is expressed in glial and fibronectin-expressing cells after spinal cord injury. Journal of Neurotrauma. 30: 806-17. PMID 23320533 DOI: 10.1089/Neu.2012.2613  0.529
2013 Theofilopoulos S, Wang Y, Kitambi SS, Sacchetti P, Sousa KM, Bodin K, Kirk J, Saltó C, Gustafsson M, Toledo EM, Karu K, Gustafsson JÃ…, Steffensen KR, Ernfors P, Sjövall J, ... ... Arenas E, et al. Brain endogenous liver X receptor ligands selectively promote midbrain neurogenesis. Nature Chemical Biology. 9: 126-33. PMID 23292650 DOI: 10.1038/Nchembio.1156  0.82
2013 ÄŒajánek L, Ganji RS, Henriques-Oliveira C, Theofilopoulos S, Koník P, Bryja V, Arenas E. Tiam1 regulates the Wnt/Dvl/Rac1 signaling pathway and the differentiation of midbrain dopaminergic neurons. Molecular and Cellular Biology. 33: 59-70. PMID 23109420 DOI: 10.1128/Mcb.00745-12  0.848
2013 Ribeiro D, Laguna Goya R, Ravindran G, Vuono R, Parish CL, Foldi C, Piroth T, Yang S, Parmar M, Nikkhah G, Hjerling-Leffler J, Lindvall O, Barker RA, Arenas E. Efficient expansion and dopaminergic differentiation of human fetal ventral midbrain neural stem cells by midbrain morphogens. Neurobiology of Disease. 49: 118-27. PMID 22940632 DOI: 10.1016/J.Nbd.2012.08.006  0.84
2013 Pereira SL, Grãos M, Rodrigues AS, Anjo SI, Carvalho RA, Oliveira PJ, Arenas E, Ramalho-Santos J. Antimycin A disturbs mESC neuronal differentiation. Plos One. DOI: 10.1371/Journal.Pone.0082095.G001  0.453
2012 Gonzalez P, Fernandez-Martos CM, Gonzalez-Fernandez C, Arenas E, Rodriguez FJ. Spatio-temporal expression pattern of frizzled receptors after contusive spinal cord injury in adult rats. Plos One. 7: e50793. PMID 23251385 DOI: 10.1371/Journal.Pone.0050793  0.506
2012 Rogers HA, Sousa S, Salto C, Arenas E, Coyle B, Grundy RG. WNT/β-catenin pathway activation in Myc immortalised cerebellar progenitor cells inhibits neuronal differentiation and generates tumours resembling medulloblastoma. British Journal of Cancer. 107: 1144-52. PMID 22929883 DOI: 10.1038/bjc.2012.377  0.345
2012 Meljon A, Theofilopoulos S, Shackleton CH, Watson GL, Javitt NB, Knölker HJ, Saini R, Arenas E, Wang Y, Griffiths WJ. Analysis of bioactive oxysterols in newborn mouse brain by LC/MS. Journal of Lipid Research. 53: 2469-83. PMID 22891291 DOI: 10.1194/Jlr.D028233  0.783
2012 Halleskog C, Dijksterhuis JP, Kilander MB, Becerril-Ortega J, Villaescusa JC, Lindgren E, Arenas E, Schulte G. Heterotrimeric G protein-dependent WNT-5A signaling to ERK1/2 mediates distinct aspects of microglia proinflammatory transformation. Journal of Neuroinflammation. 9: 111. PMID 22647544 DOI: 10.1186/1742-2094-9-111  0.796
2012 Schwartz CM, Tavakoli T, Jamias C, Park SS, Maudsley S, Martin B, Phillips TM, Yao PJ, Itoh K, Ma W, Rao MS, Arenas E, Mattson MP. Stromal factors SDF1α, sFRP1, and VEGFD induce dopaminergic neuron differentiation of human pluripotent stem cells. Journal of Neuroscience Research. 90: 1367-81. PMID 22535492 DOI: 10.1002/Jnr.23064  0.826
2012 Kele J, Andersson ER, Villaescusa JC, Cajanek L, Parish CL, Bonilla S, Toledo EM, Bryja V, Rubin JS, Shimono A, Arenas E. SFRP1 and SFRP2 dose-dependently regulate midbrain dopamine neuron development in vivo and in embryonic stem cells. Stem Cells (Dayton, Ohio). 30: 865-75. PMID 22290867 DOI: 10.1002/Stem.1049  0.84
2011 Fernández-Martos CM, González-Fernández C, González P, Maqueda A, Arenas E, Rodríguez FJ. Differential expression of Wnts after spinal cord contusion injury in adult rats. Plos One. 6: e27000. PMID 22073235 DOI: 10.1371/Journal.Pone.0027000  0.506
2011 Blakely BD, Bye CR, Fernando CV, Horne MK, Macheda ML, Stacker SA, Arenas E, Parish CL. Wnt5a regulates midbrain dopaminergic axon growth and guidance. Plos One. 6: e18373. PMID 21483795 DOI: 10.1371/Journal.Pone.0018373  0.36
2011 Tønnesen J, Parish CL, Sørensen AT, Andersson A, Lundberg C, Deisseroth K, Arenas E, Lindvall O, Kokaia M. Functional integration of grafted neural stem cell-derived dopaminergic neurons monitored by optogenetics in an in vitro Parkinson model. Plos One. 6: e17560. PMID 21394212 DOI: 10.1371/Journal.Pone.0017560  0.637
2011 Ribeiro D, Ellwanger K, Glagow D, Theofilopoulos S, Corsini NS, Martin-Villalba A, Niehrs C, Arenas E. Dkk1 regulates ventral midbrain dopaminergic differentiation and morphogenesis. Plos One. 6: e15786. PMID 21347250 DOI: 10.1371/Journal.Pone.0015786  0.848
2011 Theofilopoulos S, Karu K, Kitambi S, Sacchetti P, Sousa K, Sjovall J, Griffiths W, Arenas E. Identification and characterisation of endogenous LXR ligands in ventral midbrain development Neuroscience Research. 71: e50. DOI: 10.1016/J.Neures.2011.07.211  0.774
2010 Cajanek L, Adlerz L, Bryja V, Arenas E. WNT unrelated activities in commercially available preparations of recombinant WNT3a. Journal of Cellular Biochemistry. 111: 1077-9. PMID 20665540 DOI: 10.1002/Jcb.22771  0.784
2010 Lonardo E, Parish CL, Ponticelli S, Marasco D, Ribeiro D, Ruvo M, De Falco S, Arenas E, Minchiotti G. A small synthetic cripto blocking Peptide improves neural induction, dopaminergic differentiation, and functional integration of mouse embryonic stem cells in a rat model of Parkinson's disease. Stem Cells (Dayton, Ohio). 28: 1326-37. PMID 20641036 DOI: 10.1002/Stem.458  0.729
2010 Tang M, Villaescusa JC, Luo SX, Guitarte C, Lei S, Miyamoto Y, Taketo MM, Arenas E, Huang EJ. Interactions of Wnt/beta-catenin signaling and sonic hedgehog regulate the neurogenesis of ventral midbrain dopamine neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 9280-91. PMID 20610763 DOI: 10.1523/Jneurosci.0860-10.2010  0.787
2010 Arenas E. Towards stem cell replacement therapies for Parkinson's disease. Biochemical and Biophysical Research Communications. 396: 152-6. PMID 20494130 DOI: 10.1016/J.Bbrc.2010.04.037  0.427
2010 Jäderstad J, Jäderstad LM, Li J, Chintawar S, Salto C, Pandolfo M, Ourednik V, Teng YD, Sidman RL, Arenas E, Snyder EY, Herlenius E. Communication via gap junctions underlies early functional and beneficial interactions between grafted neural stem cells and the host. Proceedings of the National Academy of Sciences of the United States of America. 107: 5184-9. PMID 20147621 DOI: 10.1073/Pnas.0915134107  0.414
2010 Lindqvist M, Horn Z, Bryja V, Schulte G, Papachristou P, Ajima R, Dyberg C, Arenas E, Yamaguchi TP, Lagercrantz H, Ringstedt T. Vang-like protein 2 and Rac1 interact to regulate adherens junctions. Journal of Cell Science. 123: 472-83. PMID 20067994 DOI: 10.1242/Jcs.048074  0.755
2010 Villaescusa JC, Arenas E. Transplantable midbrain dopamine neurons: a moving target. Experimental Neurology. 222: 173-8. PMID 20059999 DOI: 10.1016/J.Expneurol.2009.12.028  0.789
2010 Malmersjö S, Liste I, Dyachok O, Tengholm A, Arenas E, Uhlén P. Ca2+ and cAMP signaling in human embryonic stem cell-derived dopamine neurons. Stem Cells and Development. 19: 1355-64. PMID 20043754 DOI: 10.1089/Scd.2009.0436  0.75
2010 Sousa KM, Villaescusa JC, Cajanek L, Ondr JK, Castelo-Branco G, Hofstra W, Bryja V, Palmberg C, Bergman T, Wainwright B, Lang RA, Arenas E. Wnt2 regulates progenitor proliferation in the developing ventral midbrain. The Journal of Biological Chemistry. 285: 7246-53. PMID 20018874 DOI: 10.1074/Jbc.M109.079822  0.853
2010 Inestrosa NC, Arenas E. Emerging roles of Wnts in the adult nervous system. Nature Reviews. Neuroscience. 11: 77-86. PMID 20010950 DOI: 10.1038/Nrn2755  0.33
2010 Ogundare M, Theofilopoulos S, Lockhart A, Hall LJ, Arenas E, Sjövall J, Brenton AG, Wang Y, Griffiths WJ. Cerebrospinal fluid steroidomics: are bioactive bile acids present in brain? The Journal of Biological Chemistry. 285: 4666-79. PMID 19996111 DOI: 10.1074/Jbc.M109.086678  0.769
2010 Castelo-Branco G, Andersson ER, Minina E, Sousa KM, Ribeiro D, Kokubu C, Imai K, Prakash N, Wurst W, Arenas E. Delayed dopaminergic neuron differentiation in Lrp6 mutant mice. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 239: 211-21. PMID 19795519 DOI: 10.1002/Dvdy.22094  0.846
2010 Andersson ER, Bryjova L, Biris K, Yamaguchi TP, Arenas E, Bryja V. Genetic interaction between Lrp6 and Wnt5a during mouse development. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 239: 237-45. PMID 19795512 DOI: 10.1002/Dvdy.22101  0.746
2010 Edman LC, Mira H, Arenas E. Corrigendum to "The β-chemokines CCL2 and CCL7 are two novel differentiation factors for midbrain dopaminergic precursors and neurons" [Exp. Cell Res. 314 (2008), pp. 2123-2130] Experimental Cell Research. 316: 676-677. DOI: 10.1016/J.Yexcr.2009.12.002  0.73
2009 Sacchetti P, Sousa KM, Hall AC, Liste I, Steffensen KR, Theofilopoulos S, Parish CL, Hazenberg C, Richter LA, Hovatta O, Gustafsson JA, Arenas E. Liver X receptors and oxysterols promote ventral midbrain neurogenesis in vivo and in human embryonic stem cells. Cell Stem Cell. 5: 409-19. PMID 19796621 DOI: 10.1016/J.Stem.2009.08.019  0.848
2009 Cajánek L, Ribeiro D, Liste I, Parish CL, Bryja V, Arenas E. Wnt/beta-catenin signaling blockade promotes neuronal induction and dopaminergic differentiation in embryonic stem cells. Stem Cells (Dayton, Ohio). 27: 2917-27. PMID 19725118 DOI: 10.1002/Stem.210  0.853
2009 Rawal N, Corti O, Sacchetti P, Ardilla-Osorio H, Sehat B, Brice A, Arenas E. Parkin protects dopaminergic neurons from excessive Wnt/beta-catenin signaling. Biochemical and Biophysical Research Communications. 388: 473-8. PMID 19591802 DOI: 10.1016/J.Bbrc.2009.07.014  0.841
2009 Kunke D, Bryja V, Mygland L, Arenas E, Krauss S. Inhibition of canonical Wnt signaling promotes gliogenesis in P0-NSCs. Biochemical and Biophysical Research Communications. 386: 628-33. PMID 19545542 DOI: 10.1016/J.Bbrc.2009.06.084  0.664
2009 Wang Y, Sousa KM, Bodin K, Theofilopoulos S, Sacchetti P, Hornshaw M, Woffendin G, Karu K, Sjövall J, Arenas E, Griffiths WJ. Targeted lipidomic analysis of oxysterols in the embryonic central nervous system. Molecular Biosystems. 5: 529-41. PMID 19381367 DOI: 10.1039/B819502A  0.775
2009 Yang DH, Yoon JY, Lee SH, Bryja V, Andersson ER, Arenas E, Kwon YG, Choi KY. Wnt5a is required for endothelial differentiation of embryonic stem cells and vascularization via pathways involving both Wnt/beta-catenin and protein kinase Calpha. Circulation Research. 104: 372-9. PMID 19096028 DOI: 10.1161/Circresaha.108.185405  0.76
2009 Bryja V, Andersson ER, Schambony A, Esner M, Bryjová L, Biris KK, Hall AC, Kraft B, Cajanek L, Yamaguchi TP, Buckingham M, Arenas E. The extracellular domain of Lrp5/6 inhibits noncanonical Wnt signaling in vivo. Molecular Biology of the Cell. 20: 924-36. PMID 19056682 DOI: 10.1091/Mbc.E08-07-0711  0.791
2008 Jung GA, Yoon JY, Moon BS, Yang DH, Kim HY, Lee SH, Bryja V, Arenas E, Choi KY. Valproic acid induces differentiation and inhibition of proliferation in neural progenitor cells via the beta-catenin-Ras-ERK-p21Cip/WAF1 pathway. Bmc Cell Biology. 9: 66. PMID 19068119 DOI: 10.1186/1471-2121-9-66  0.648
2008 Saltó C, Saindon E, Bolin M, Kanciurzewska A, Fahlman M, Jager EW, Tengvall P, Arenas E, Berggren M. Control of neural stem cell adhesion and density by an electronic polymer surface switch. Langmuir : the Acs Journal of Surfaces and Colloids. 24: 14133-8. PMID 19053638 DOI: 10.1021/La8028337  0.345
2008 Andersson ER, Prakash N, Cajanek L, Minina E, Bryja V, Bryjova L, Yamaguchi TP, Hall AC, Wurst W, Arenas E. Wnt5a regulates ventral midbrain morphogenesis and the development of A9-A10 dopaminergic cells in vivo. Plos One. 3: e3517. PMID 18953410 DOI: 10.1371/Journal.Pone.0003517  0.842
2008 Bryja V, Schambony A, Cajánek L, Dominguez I, Arenas E, Schulte G. Beta-arrestin and casein kinase 1/2 define distinct branches of non-canonical WNT signalling pathways. Embo Reports. 9: 1244-50. PMID 18953287 DOI: 10.1038/Embor.2008.193  0.783
2008 Edman LC, Mira H, Erices A, Malmersjö S, Andersson E, Uhlén P, Arenas E. Alpha-chemokines regulate proliferation, neurogenesis, and dopaminergic differentiation of ventral midbrain precursors and neurospheres. Stem Cells (Dayton, Ohio). 26: 1891-900. PMID 18436867 DOI: 10.1634/Stemcells.2007-0753  0.839
2008 Edman LC, Mira H, Arenas E. The beta-chemokines CCL2 and CCL7 are two novel differentiation factors for midbrain dopaminergic precursors and neurons. Experimental Cell Research. 314: 2123-30. PMID 18420193 DOI: 10.1016/J.Yexcr.2008.02.019  0.785
2008 Arenas E. Foxa2: the rise and fall of dopamine neurons. Cell Stem Cell. 2: 110-2. PMID 18371430 DOI: 10.1016/J.Stem.2008.01.012  0.487
2008 Bonilla S, Hall AC, Pinto L, Attardo A, Götz M, Huttner WB, Arenas E. Identification of midbrain floor plate radial glia-like cells as dopaminergic progenitors. Glia. 56: 809-20. PMID 18351630 DOI: 10.1002/Glia.20654  0.802
2008 Andäng M, Hjerling-Leffler J, Moliner A, Lundgren TK, Castelo-Branco G, Nanou E, Pozas E, Bryja V, Halliez S, Nishimaru H, Wilbertz J, Arenas E, Koltzenburg M, Charnay P, El Manira A, et al. Histone H2AX-dependent GABA(A) receptor regulation of stem cell proliferation. Nature. 451: 460-4. PMID 18185516 DOI: 10.1038/Nature06488  0.812
2008 Parish CL, Castelo-Branco G, Rawal N, Tonnesen J, Sorensen AT, Salto C, Kokaia M, Lindvall O, Arenas E. Wnt5a-treated midbrain neural stem cells improve dopamine cell replacement therapy in parkinsonian mice. The Journal of Clinical Investigation. 118: 149-60. PMID 18060047 DOI: 10.1172/Jci32273  0.85
2008 Prakash N, Andersson E, Minina E, Klafke R, Simeone A, Arenas E, Wurst W. [ST3]: Genetic pathways controlling midbrain dopaminergic neuron development in vivo International Journal of Developmental Neuroscience. 26: 833-833. DOI: 10.1016/J.Ijdevneu.2008.09.029  0.583
2007 Parish CL, Arenas E. Stem-cell-based strategies for the treatment of Parkinson's disease. Neuro-Degenerative Diseases. 4: 339-47. PMID 17627139 DOI: 10.1159/000101892  0.374
2007 Parish CL, Beljajeva A, Arenas E, Simon A. Midbrain dopaminergic neurogenesis and behavioural recovery in a salamander lesion-induced regeneration model. Development (Cambridge, England). 134: 2881-7. PMID 17611231 DOI: 10.1242/Dev.002329  0.681
2007 Bryja V, Gradl D, Schambony A, Arenas E, Schulte G. Beta-arrestin is a necessary component of Wnt/beta-catenin signaling in vitro and in vivo. Proceedings of the National Academy of Sciences of the United States of America. 104: 6690-5. PMID 17426148 DOI: 10.1073/Pnas.0611356104  0.711
2007 Bryja V, Schulte G, Rawal N, Grahn A, Arenas E. Wnt-5a induces Dishevelled phosphorylation and dopaminergic differentiation via a CK1-dependent mechanism. Journal of Cell Science. 120: 586-95. PMID 17244647 DOI: 10.1242/Jcs.03368  0.797
2007 Sousa KM, Mira H, Hall AC, Jansson-Sjöstrand L, Kusakabe M, Arenas E. Microarray analyses support a role for Nurr1 in resistance to oxidative stress and neuronal differentiation in neural stem cells. Stem Cells (Dayton, Ohio). 25: 511-9. PMID 17038671 DOI: 10.1634/Stemcells.2006-0238  0.798
2007 Bryja V, Schulte G, Arenas E. Wnt-3a utilizes a novel low dose and rapid pathway that does not require casein kinase 1-mediated phosphorylation of Dvl to activate beta-catenin. Cellular Signalling. 19: 610-6. PMID 17027228 DOI: 10.1016/J.Cellsig.2006.08.011  0.718
2007 Pineda JR, Rubio N, Akerud P, Urbán N, Badimon L, Arenas E, Alberch J, Blanco J, Canals JM. Neuroprotection by GDNF-secreting stem cells in a Huntington's disease model: optical neuroimage tracking of brain-grafted cells. Gene Therapy. 14: 118-28. PMID 16943855 DOI: 10.1038/Sj.Gt.3302847  0.731
2007 Rawal N, Parish C, Castelo-Branco G, Arenas E. Inhibition of JNK increases survival of transplanted dopamine neurons in Parkinsonian rats. Cell Death and Differentiation. 14: 381-3. PMID 16858428 DOI: 10.1038/Sj.Cdd.4402010  0.798
2006 Bryja V, Bonilla S, Arenas E. Derivation of mouse embryonic stem cells. Nature Protocols. 1: 2082-7. PMID 17487198 DOI: 10.1038/Nprot.2006.355  0.596
2006 Holm PC, Rodríguez FJ, Kele J, Castelo-Branco G, Kitajewski J, Arenas E. BMPs, FGF8 and Wnts regulate the differentiation of locus coeruleus noradrenergic neuronal precursors. Journal of Neurochemistry. 99: 343-52. PMID 16987254 DOI: 10.1111/J.1471-4159.2006.04039.X  0.835
2006 Castelo-Branco G, Arenas E. Function of Wnts in dopaminergic neuron development. Neuro-Degenerative Diseases. 3: 5-11. PMID 16909030 DOI: 10.1159/000092086  0.767
2006 Bakshi A, Shimizu S, Keck CA, Cho S, LeBold DG, Morales D, Arenas E, Snyder EY, Watson DJ, McIntosh TK. Neural progenitor cells engineered to secrete GDNF show enhanced survival, neuronal differentiation and improve cognitive function following traumatic brain injury. The European Journal of Neuroscience. 23: 2119-34. PMID 16630059 DOI: 10.1111/J.1460-9568.2006.04743.X  0.393
2006 Rawal N, Castelo-Branco G, Sousa KM, Kele J, Kobayashi K, Okano H, Arenas E. Dynamic temporal and cell type-specific expression of Wnt signaling components in the developing midbrain. Experimental Cell Research. 312: 1626-36. PMID 16510140 DOI: 10.1016/J.Yexcr.2006.01.032  0.849
2006 Kele J, Simplicio N, Ferri AL, Mira H, Guillemot F, Arenas E, Ang SL. Neurogenin 2 is required for the development of ventral midbrain dopaminergic neurons. Development (Cambridge, England). 133: 495-505. PMID 16410412 DOI: 10.1242/Dev.02223  0.826
2006 Bryja V, Bonilla S, Cajánek L, Parish CL, Schwartz CM, Luo Y, Rao MS, Arenas E. An efficient method for the derivation of mouse embryonic stem cells. Stem Cells (Dayton, Ohio). 24: 844-9. PMID 16339993 DOI: 10.1634/Stemcells.2005-0444  0.801
2006 Prakash N, Brodski C, Naserke T, Puelles E, Gogoi R, Hall A, Panhuysen M, Echevarria D, Sussel L, Weisenhorn DM, Martinez S, Arenas E, Simeone A, Wurst W. A Wnt1-regulated genetic network controls the identity and fate of midbrain-dopaminergic progenitors in vivo. Development (Cambridge, England). 133: 89-98. PMID 16339193 DOI: 10.1242/Dev.02181  0.828
2006 Castelo-Branco G, Sousa KM, Bryja V, Pinto L, Wagner J, Arenas E. Ventral midbrain glia express region-specific transcription factors and regulate dopaminergic neurogenesis through Wnt-5a secretion. Molecular and Cellular Neurosciences. 31: 251-62. PMID 16243537 DOI: 10.1016/J.Mcn.2005.09.014  0.833
2005 Schwartz CM, Spivak CE, Baker SC, McDaniel TK, Loring JF, Nguyen C, Chrest FJ, Wersto R, Arenas E, Zeng X, Freed WJ, Rao MS. NTera2: a model system to study dopaminergic differentiation of human embryonic stem cells. Stem Cells and Development. 14: 517-34. PMID 16305337 DOI: 10.1089/Scd.2005.14.517  0.791
2005 Shariatmadari M, Peyronnet J, Papachristou P, Horn Z, Sousa KM, Arenas E, Ringstedt T. Increased Wnt levels in the neural tube impair the function of adherens junctions during neurulation. Molecular and Cellular Neurosciences. 30: 437-51. PMID 16154760 DOI: 10.1016/J.Mcn.2005.08.008  0.383
2005 Arenas E. Engineering a dopaminergic phenotype in stem/precursor cells: role of Nurr1, glia-derived signals, and Wnts. Annals of the New York Academy of Sciences. 1049: 51-66. PMID 15965107 DOI: 10.1196/Annals.1334.007  0.509
2005 Bergman P, Termén S, Johansson L, Nyström L, Arenas E, Jonsson AB, Hökfelt T, Gudmundsson GH, Agerberth B. The antimicrobial peptide rCRAMP is present in the central nervous system of the rat. Journal of Neurochemistry. 93: 1132-40. PMID 15934934 DOI: 10.1111/J.1471-4159.2005.03081.X  0.473
2005 Parish CL, Parisi S, Persico MG, Arenas E, Minchiotti G. Cripto as a target for improving embryonic stem cell-based therapy in Parkinson's disease. Stem Cells (Dayton, Ohio). 23: 471-6. PMID 15790767 DOI: 10.1634/Stemcells.2004-0294  0.418
2005 Schulte G, Bryja V, Rawal N, Castelo-Branco G, Sousa KM, Arenas E. Purified Wnt-5a increases differentiation of midbrain dopaminergic cells and dishevelled phosphorylation. Journal of Neurochemistry. 92: 1550-3. PMID 15748172 DOI: 10.1111/J.1471-4159.2004.03022.X  0.801
2004 Brunkhorst A, Neuman T, Hall A, Arenas E, Bartfai T, Hermanson O, Metsis M. Novel isoforms of the TFIID subunit TAF4 modulate nuclear receptor-mediated transcriptional activity. Biochemical and Biophysical Research Communications. 325: 574-9. PMID 15530431 DOI: 10.1016/J.Bbrc.2004.10.078  0.79
2004 Castelo-Branco G, Rawal N, Arenas E. GSK-3beta inhibition/beta-catenin stabilization in ventral midbrain precursors increases differentiation into dopamine neurons. Journal of Cell Science. 117: 5731-7. PMID 15522889 DOI: 10.1242/Jcs.01505  0.833
2004 Grothe C, Timmer M, Scholz T, Winkler C, Nikkhah G, Claus P, Itoh N, Arenas E. Fibroblast growth factor-20 promotes the differentiation of Nurr1-overexpressing neural stem cells into tyrosine hydroxylase-positive neurons. Neurobiology of Disease. 17: 163-70. PMID 15474354 DOI: 10.1016/J.Nbd.2004.07.007  0.543
2004 Sieber BA, Kuzmin A, Canals JM, Danielsson A, Paratcha G, Arenas E, Alberch J, Ogren SO, Ibáñez CF. Disruption of EphA/ephrin-a signaling in the nigrostriatal system reduces dopaminergic innervation and dissociates behavioral responses to amphetamine and cocaine. Molecular and Cellular Neurosciences. 26: 418-28. PMID 15234346 DOI: 10.1016/J.Mcn.2004.03.009  0.737
2004 Castelo-Branco G, Wagner J, Rodriguez FJ, Kele J, Sousa K, Rawal N, Pasolli HA, Fuchs E, Kitajewski J, Arenas E. Erratum: Differential regulation of midbrain dopaminergic neuron development by Wnt-1, Wnt-3a, and Wnt-5a (Proceedings of the National Academy of Sciences of the United States of America (October 28, 2003) 100:22 (1247-12752)) Proceedings of the National Academy of Sciences of the United States of America. 101. DOI: 10.1073/Pnas.0407231101  0.804
2003 Wallen-Mackenzie A, Mata de Urquiza A, Petersson S, Rodriguez FJ, Friling S, Wagner J, Ordentlich P, Lengqvist J, Heyman RA, Arenas E, Perlmann T. Nurr1-RXR heterodimers mediate RXR ligand-induced signaling in neuronal cells. Genes & Development. 17: 3036-47. PMID 14681209 DOI: 10.1101/Gad.276003  0.72
2003 Castelo-Branco G, Wagner J, Rodriguez FJ, Kele J, Sousa K, Rawal N, Pasolli HA, Fuchs E, Kitajewski J, Arenas E. Differential regulation of midbrain dopaminergic neuron development by Wnt-1, Wnt-3a, and Wnt-5a. Proceedings of the National Academy of Sciences of the United States of America. 100: 12747-52. PMID 14557550 DOI: 10.1073/Pnas.1534900100  0.835
2003 Holm PC, Rodríguez FJ, Kresse A, Canals JM, Silos-Santiago I, Arenas E. Crucial role of TrkB ligands in the survival and phenotypic differentiation of developing locus coeruleus noradrenergic neurons. Development (Cambridge, England). 130: 3535-45. PMID 12810600 DOI: 10.1242/Dev.00565  0.818
2003 Lillesaar C, Arenas E, Hildebrand C, Fried K. Responses of rat trigeminal neurones to dental pulp cells or fibroblasts overexpressing neurotrophic factors in vitro. Neuroscience. 119: 443-51. PMID 12770558 DOI: 10.1016/S0306-4522(02)00938-7  0.405
2003 Hall AC, Mira H, Wagner J, Arenas E. Region-specific effects of glia on neuronal induction and differentiation with a focus on dopaminergic neurons. Glia. 43: 47-51. PMID 12761866 DOI: 10.1002/Glia.10229  0.812
2002 Tcherpakov M, Bronfman FC, Conticello SG, Vaskovsky A, Levy Z, Niinobe M, Yoshikawa K, Arenas E, Fainzilber M. The p75 neurotrophin receptor interacts with multiple MAGE proteins. The Journal of Biological Chemistry. 277: 49101-4. PMID 12414813 DOI: 10.1074/Jbc.C200533200  0.304
2002 Akerud P, Holm PC, Castelo-Branco G, Sousa K, Rodriguez FJ, Arenas E. Persephin-overexpressing neural stem cells regulate the function of nigral dopaminergic neurons and prevent their degeneration in a model of Parkinson's disease. Molecular and Cellular Neurosciences. 21: 205-22. PMID 12401443 DOI: 10.1006/Mcne.2002.1171  0.803
2002 Holm PC, Akerud P, Wagner J, Arenas E. Neurturin is a neuritogenic but not a survival factor for developing and adult central noradrenergic neurons. Journal of Neurochemistry. 81: 1318-27. PMID 12068079 DOI: 10.1046/J.1471-4159.2002.00926.X  0.714
2002 Arenas E. Stem cells in the treatment of Parkinson's disease. Brain Research Bulletin. 57: 795-808. PMID 12031276 DOI: 10.1016/S0361-9230(01)00772-9  0.472
2002 Marco S, Pérez-Navarro E, Tolosa E, Arenas E, Alberch J. Striatopallidal neurons are selectively protected by neurturin in an excitotoxic model of Huntington's disease. Journal of Neurobiology. 50: 323-32. PMID 11891666 DOI: 10.1002/Neu.10033  0.644
2002 Reiriz J, Holm PC, Alberch J, Arenas E. BMP-2 and cAMP elevation confer locus coeruleus neurons responsiveness to multiple neurotrophic factors. Journal of Neurobiology. 50: 291-304. PMID 11891664 DOI: 10.1002/Neu.10034  0.661
2001 Akerud P, Canals JM, Snyder EY, Arenas E. Neuroprotection through delivery of glial cell line-derived neurotrophic factor by neural stem cells in a mouse model of Parkinson's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 8108-18. PMID 11588183 DOI: 10.1523/Jneurosci.21-20-08108.2001  0.687
2001 Gratacòs E, Pérez-Navarro E, Tolosa E, Arenas E, Alberch J. Neuroprotection of striatal neurons against kainate excitotoxicity by neurotrophins and GDNF family members. Journal of Neurochemistry. 78: 1287-96. PMID 11579137 DOI: 10.1046/J.1471-4159.2001.00538.X  0.659
2001 Naveilhan P, Canals JM, Arenas E, Ernfors P. Distinct roles of the Y1 and Y2 receptors on neuropeptide Y-induced sensitization to sedation. Journal of Neurochemistry. 78: 1201-7. PMID 11579129 DOI: 10.1046/J.1471-4159.2001.00534.X  0.738
2001 Naveilhan P, Canals JM, Valjakka A, Vartiainen J, Arenas E, Ernfors P. Neuropeptide Y alters sedation through a hypothalamic Y1-mediated mechanism. The European Journal of Neuroscience. 13: 2241-6. PMID 11454027 DOI: 10.1046/J.0953-816X.2001.01601.X  0.751
2001 Ferrer I, Krupinski J, Goutan E, Martí E, Ambrosio S, Arenas E. Brain-derived neurotrophic factor reduces cortical cell death by ischemia after middle cerebral artery occlusion in the rat. Acta Neuropathologica. 101: 229-38. PMID 11307622 DOI: 10.1007/S004010000268  0.355
2001 Canals JM, Checa N, Marco S, Akerud P, Michels A, Pérez-Navarro E, Tolosa E, Arenas E, Alberch J. Expression of brain-derived neurotrophic factor in cortical neurons is regulated by striatal target area. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 117-24. PMID 11150327 DOI: 10.1523/Jneurosci.21-01-00117.2001  0.733
2000 Espejo M, Cutillas B, Arenas E, Ambrosio S. Increased Survival of Dopaminergic Neurons in Striatal Grafts of Fetal Ventral Mesencephalic Cells Exposed to Neurotrophin-3 or Glial Cell Line-Derived Neurotrophic Factor. Cell Transplantation. 9: 45-53. PMID 28876111 DOI: 10.1177/096368970000900107  0.312
2000 JerregÃ¥rd H, Akerud P, Arenas E, Hildebrand C. Fibroblast-like cells from rat plantar skin and neurotrophin-transfected 3T3 fibroblasts influence neurite growth from rat sensory neurons in vitro. Journal of Neurocytology. 29: 653-63. PMID 11353289 DOI: 10.1023/A:1010883320683  0.423
2000 Pérez-Navarro E, Canudas AM, Akerund P, Alberch J, Arenas E. Brain-derived neurotrophic factor, neurotrophin-3, and neurotrophin-4/5 prevent the death of striatal projection neurons in a rodent model of Huntington's disease. Journal of Neurochemistry. 75: 2190-9. PMID 11183872 DOI: 10.1046/J.1471-4159.2000.0752190.X  0.652
2000 Pérez-Navarro E, Akerud P, Marco S, Canals JM, Tolosa E, Arenas E, Alberch J. Neurturin protects striatal projection neurons but not interneurons in a rat model of Huntington's disease. Neuroscience. 98: 89-96. PMID 10858615 DOI: 10.1016/S0306-4522(00)00074-9  0.764
1999 Naveilhan P, Hassani H, Canals JM, Ekstrand AJ, Larefalk A, Chhajlani V, Arenas E, Gedda K, Svensson L, Thoren P, Ernfors P. Normal feeding behavior, body weight and leptin response require the neuropeptide Y Y2 receptor. Nature Medicine. 5: 1188-93. PMID 10502824 DOI: 10.1038/13514  0.742
1999 Wagner J, Akerud P, Castro DS, Holm PC, Canals JM, Snyder EY, Perlmann T, Arenas E. Induction of a midbrain dopaminergic phenotype in Nurr1-overexpressing neural stem cells by type 1 astrocytes. Nature Biotechnology. 17: 653-9. PMID 10404157 DOI: 10.1038/10862  0.793
1999 Pérez-Navarro E, Alberch J, Neveu I, Arenas E. Brain-derived neurotrophic factor, neurotrophin-3 and neurotrophin-4/5 differentially regulate the phenotype and prevent degenerative changes in striatal projection neurons after excitotoxicity in vivo. Neuroscience. 91: 1257-64. PMID 10391433 DOI: 10.1016/S0306-4522(98)00723-4  0.66
1999 Akerud P, Alberch J, Eketjäll S, Wagner J, Arenas E. Differential effects of glial cell line-derived neurotrophic factor and neurturin on developing and adult substantia nigra dopaminergic neurons. Journal of Neurochemistry. 73: 70-8. PMID 10386956 DOI: 10.1046/J.1471-4159.1999.0730070.X  0.794
1999 Pérez-Navarro E, Arenas E, Marco S, Alberch J. Intrastriatal grafting of a GDNF-producing cell line protects striatonigral neurons from quinolinic acid excitotoxicity in vivo. The European Journal of Neuroscience. 11: 241-9. PMID 9987028 DOI: 10.1046/J.1460-9568.1999.00433.X  0.667
1998 Canals JM, Marco S, Checa N, Michels A, Pérez-Navarro E, Arenas E, Alberch J. Differential regulation of the expression of nerve growth factor, brain-derived neurotrophic factor, and neurotrophin-3 after excitotoxicity in a rat model of Huntington's disease. Neurobiology of Disease. 5: 357-64. PMID 10069578 DOI: 10.1006/Nbdi.1998.0211  0.715
1998 Ringstedt T, Linnarsson S, Wagner J, Lendahl U, Kokaia Z, Arenas E, Ernfors P, Ibáñez CF. BDNF regulates reelin expression and Cajal-Retzius cell development in the cerebral cortex. Neuron. 21: 305-15. PMID 9728912 DOI: 10.1016/S0896-6273(00)80540-1  0.802
1998 Naveilhan P, Neveu I, Arenas E, Ernfors P. Complementary and overlapping expression of Y1, Y2 and Y5 receptors in the developing and adult mouse nervous system. Neuroscience. 87: 289-302. PMID 9722158 DOI: 10.1016/S0306-4522(98)00141-9  0.706
1998 Ferrer I, Ballabriga J, Martí E, Pérez E, Alberch J, Arenas E. BDNF up-regulates TrkB protein and prevents the death of CA1 neurons following transient forebrain ischemia. Brain Pathology (Zurich, Switzerland). 8: 253-61. PMID 9546284 DOI: 10.1111/J.1750-3639.1998.Tb00151.X  0.604
1998 Ferré S, Torvinen M, Antoniou K, Irenius E, Civelli O, Arenas E, Fredholm BB, Fuxe K. Adenosine A1 receptor-mediated modulation of dopamine D1 receptors in stably cotransfected fibroblast cells. The Journal of Biological Chemistry. 273: 4718-24. PMID 9468534 DOI: 10.1074/Jbc.273.8.4718  0.411
1996 Dasgupta S, Ferré S, Kull B, Hedlund PB, Finnman UB, Ahlberg S, Arenas E, Fredholm BB, Fuxe K. Adenosine A2A receptors modulate the binding characteristics of dopamine D2 receptors in stably cotransfected fibroblast cells. European Journal of Pharmacology. 316: 325-31. PMID 8982704 DOI: 10.1016/S0014-2999(96)00665-6  0.49
1996 Dasgupta S, Li XM, Jansson A, Finnman UB, Matsui T, Rinken A, Arenas E, Agnati LF, Fuxe K. Regulation of dopamine D2 receptor affinity by cholecystokinin octapeptide in fibroblast cells cotransfected with human CCKB and D2L receptor cDNAs. Brain Research. Molecular Brain Research. 36: 292-9. PMID 8965650 DOI: 10.1016/0169-328X(95)00283-X  0.311
1996 Pérez-Navarro E, Arenas E, Reiriz J, Calvo N, Alberch J. Glial cell line-derived neurotrophic factor protects striatal calbindin-immunoreactive neurons from excitotoxic damage. Neuroscience. 75: 345-52. PMID 8931001 DOI: 10.1016/0306-4522(96)00336-3  0.669
1996 Arenas E, Akerud P, Wong V, Boylan C, Persson H, Lindsay RM, Altar CA. Effects of BDNF and NT-4/5 on striatonigral neuropeptides or nigral GABA neurons in vivo. The European Journal of Neuroscience. 8: 1707-17. PMID 8921261 DOI: 10.1111/J.1460-9568.1996.Tb01314.X  0.591
1996 Trupp M, Arenas E, Fainzilber M, Nilsson AS, Sieber BA, Grigoriou M, Kilkenny C, Salazar-Grueso E, Pachnis V, Arumäe U. Functional receptor for GDNF encoded by the c-ret proto-oncogene. Nature. 381: 785-9. PMID 8657281 DOI: 10.1038/381785A0  0.461
1996 Neveu I, Arenas E. Neurotrophins promote the survival and development of neurons in the cerebellum of hypothyroid rats in vivo. The Journal of Cell Biology. 133: 631-46. PMID 8636237 DOI: 10.1083/Jcb.133.3.631  0.465
1995 Arenas E, Trupp M, Akerud P, Ibáñez CF. GDNF prevents degeneration and promotes the phenotype of brain noradrenergic neurons in vivo. Neuron. 15: 1465-73. PMID 8845169 DOI: 10.1016/0896-6273(95)90024-1  0.456
1995 Timmusk T, Lendahl U, Funakoshi H, Arenas E, Persson H, Metsis M. Identification of brain-derived neurotrophic factor promoter regions mediating tissue-specific, axotomy-, and neuronal activity-induced expression in transgenic mice. The Journal of Cell Biology. 128: 185-99. PMID 7822414 DOI: 10.1083/Jcb.128.1.185  0.52
1995 Trupp M, Rydén M, Jörnvall H, Funakoshi H, Timmusk T, Arenas E, Ibáñez CF. Peripheral expression and biological activities of GDNF, a new neurotrophic factor for avian and mammalian peripheral neurons. The Journal of Cell Biology. 130: 137-48. PMID 7790368 DOI: 10.1083/Jcb.130.1.137  0.481
1995 Funakoshi H, Belluardo N, Arenas E, Yamamoto Y, Casabona A, Persson H, Ibáñez CF. Muscle-derived neurotrophin-4 as an activity-dependent trophic signal for adult motor neurons. Science (New York, N.Y.). 268: 1495-9. PMID 7770776 DOI: 10.1126/Science.7770776  0.491
1994 Arenas E, Persson H. Neurotrophin-3 prevents the death of adult central noradrenergic neurons in vivo. Nature. 367: 368-71. PMID 8114936 DOI: 10.1038/367368A0  0.591
1994 Pérez-Navarro E, Alberch J, Arenas E, Calvo N, Marsal J. Nerve growth factor and basic fibroblast growth factor protect cholinergic neurons against quinolinic acid excitotoxicity in rat neostriatum. The European Journal of Neuroscience. 6: 706-11. PMID 8075815 DOI: 10.1111/J.1460-9568.1994.Tb00982.X  0.553
1993 Pérez-Navarro E, Alberch J, Arenas E, Marsal J. Nerve growth factor and its receptor are differentially modified by chronic naltrexone treatment during rat brain development. Neuroscience Letters. 149: 47-50. PMID 8469378 DOI: 10.1016/0304-3940(93)90344-K  0.534
1993 Metsis M, Timmusk T, Arenas E, Persson H. Differential usage of multiple brain-derived neurotrophic factor promoters in the rat brain following neuronal activation. Proceedings of the National Academy of Sciences of the United States of America. 90: 8802-6. PMID 8415610 DOI: 10.1073/Pnas.90.19.8802  0.497
1993 Ibáñez CF, Ernfors P, Timmusk T, Ip NY, Arenas E, Yancopoulos GD, Persson H. Neurotrophin-4 is a target-derived neurotrophic factor for neurons of the trigeminal ganglion. Development (Cambridge, England). 117: 1345-53. PMID 8404536  0.767
1993 Arenas E, Pérez-Navarro E, Alberch J, Marsal J. Selective resistance of tachykinin-responsive cholinergic neurons in the quinolinic acid lesioned neostriatum. Brain Research. 603: 317-20. PMID 7681719 DOI: 10.1016/0006-8993(93)91254-P  0.573
1993 Alberch J, Arenas E, Pérez-Navarro E, Marsal J. Control of tachykinin-evoked acetylcholine release from rat striatal slices by dopaminergic neurons. Naunyn-Schmiedeberg's Archives of Pharmacology. 348: 445-9. PMID 7509458 DOI: 10.1007/Bf00173201  0.564
1991 Arenas E, Alberch J, Pérez-Navarro E, Solsona C, Marsal J. Neostriatal dopaminergic terminals prevent the GABAergic involvement in the mu- and delta-opioid inhibition of KCl-evoked endogenous acetylcholine release. Brain Research. 556: 349-52. PMID 1933369 DOI: 10.1016/0006-8993(91)90329-T  0.528
1991 Arenas E, Alberch J, Marsal J. Dopaminergic system mediates only delta-opiate inhibition of endogenous acetylcholine release evoked by glutamate from rat striatal slices. Neuroscience. 42: 707-14. PMID 1683474 DOI: 10.1016/0306-4522(91)90039-Q  0.522
1991 Alberch J, Pérez-Navarro E, Arenas E, Marsal J. Involvement of nerve growth factor and its receptor in the regulation of the cholinergic function in aged rats. Journal of Neurochemistry. 57: 1483-7. PMID 1655975 DOI: 10.1111/J.1471-4159.1991.Tb06342.X  0.524
1991 Arenas E, Alberch J, Perez-Navarro E, Solsona C, Marsal J. Neurokinin receptors differentially mediate endogenous acetylcholine release evoked by tachykinins in the neostriatum. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 11: 2332-8. PMID 1651375 DOI: 10.1523/Jneurosci.11-08-02332.1991  0.588
1990 Alberch J, Arenas E, Sánchez Arroyos R, Marsal J. Excitatory amino acids release endogenous acetylcholine from rat striatal slices: Regulation by gamma-aminobutyric acid. Neurochemistry International. 17: 107-16. PMID 20504609 DOI: 10.1016/0197-0186(90)90074-4  0.517
1990 Arenas E, Marsal J, Alberch J. GABAA and GABAB antagonists prevent the opioid inhibition of endogenous acetylcholine release evoked by glutamate from rat neostriatal slices. Neuroscience Letters. 120: 201-4. PMID 1981386 DOI: 10.1016/0304-3940(90)90038-B  0.525
1990 Arenas E, Alberch J, Sanchez Arroyos R, Marsal J. Effect of opioids on acetylcholine release evoked by K+ or glutamic acid from rat neostriatal slices. Brain Research. 523: 51-6. PMID 1976420 DOI: 10.1016/0006-8993(90)91633-R  0.523
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