D. Kacy Cullen - Publications

Affiliations: 
Neurosurgery University of Pennsylvania/Philadelphia VA Medical Center 

72 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Das S, Browne KD, Laimo FA, Maggiore JC, Hilman MC, Kaisaier H, Aguilar CA, Ali ZS, Mourkioti F, Cullen DK. Pre-innervated tissue-engineered muscle promotes a pro-regenerative microenvironment following volumetric muscle loss. Communications Biology. 3: 330. PMID 32587337 DOI: 10.1038/s42003-020-1056-4  0.6
2020 Das S, Gordián-Vélez WJ, Ledebur HC, Mourkioti F, Rompolas P, Chen HI, Serruya MD, Cullen DK. Innervation: the missing link for biofabricated tissues and organs. Npj Regenerative Medicine. 5: 11. PMID 32550009 DOI: 10.1038/s41536-020-0096-1  0.68
2020 Katiyar KS, Struzyna LA, Morand JP, Burrell JC, Clements B, Laimo FA, Browne KD, Kohn J, Ali Z, Ledebur HC, Smith DH, Cullen DK. Tissue Engineered Axon Tracts Serve as Living Scaffolds to Accelerate Axonal Regeneration and Functional Recovery Following Peripheral Nerve Injury in Rats. Frontiers in Bioengineering and Biotechnology. 8: 492. PMID 32523945 DOI: 10.3389/fbioe.2020.00492  0.92
2020 Marinov T, López Sánchez HA, Yuchi L, Adewole DO, Cullen DK, Kraft RH. A computational model of bidirectional axonal growth in micro-tissue engineered neuronal networks (micro-TENNs). In Silico Biology. PMID 32390612 DOI: 10.3233/ISB-180172  0.68
2020 Keating CE, Browne K, Duda JE, Cullen DK. Neurons in Subcortical Oculomotor Regions are Vulnerable to Plasma Membrane Damage after Repetitive Diffuse Traumatic Brain Injury in Swine. Journal of Neurotrauma. PMID 32178582 DOI: 10.1089/neu.2019.6738  0.52
2020 Grovola MR, Paleologos N, Wofford KL, Harris JP, Browne KD, Johnson V, Duda JE, Wolf JA, Cullen DK. Mossy cell hypertrophy and synaptic changes in the hilus following mild diffuse traumatic brain injury in pigs. Journal of Neuroinflammation. 17: 44. PMID 32005260 DOI: 10.1186/s12974-020-1720-0  0.68
2020 Harris JP, Burrell JC, Struzyna LA, Chen HI, Serruya MD, Wolf JA, Duda JE, Cullen DK. Emerging regenerative medicine and tissue engineering strategies for Parkinson's disease. Npj Parkinson's Disease. 6: 4. PMID 31934611 DOI: 10.1038/s41531-019-0105-5  0.68
2019 Wofford KL, Singh BS, Cullen DK, Spiller KL. Biomaterial-mediated Reprogramming of Monocytes via Microparticle Phagocytosis for Sustained Modulation of Macrophage Phenotype. Acta Biomaterialia. PMID 31731024 DOI: 10.1016/j.actbio.2019.11.021  0.36
2019 Cullen DK, Gordián-Vélez WJ, Struzyna LA, Jgamadze D, Lim J, Wofford KL, Browne KD, Chen HI. Bundled Three-Dimensional Human Axon Tracts Derived from Brain Organoids. Iscience. 21: 57-67. PMID 31654854 DOI: 10.1016/j.isci.2019.10.004  0.64
2019 Katiyar KS, Struzyna LA, Das S, Cullen DK. "Stretch-Growth" of Motor Axons in Custom Mechanobioreactors to Generate Long-Projecting Axonal Constructs. Journal of Tissue Engineering and Regenerative Medicine. PMID 31469944 DOI: 10.1002/term.2955  0.8
2019 Wofford KL, Loane DJ, Cullen DK. Acute drivers of neuroinflammation in traumatic brain injury. Neural Regeneration Research. 14: 1481-1489. PMID 31089036 DOI: 10.4103/1673-5374.255958  0.36
2019 Ulyanova AV, Cottone C, Adam CD, Gagnon KG, Cullen DK, Holtzman T, Jamieson BG, Koch PF, Chen HI, Johnson VE, Wolf JA. Multichannel Silicon Probes for Awake Hippocampal Recordings in Large Animals. Frontiers in Neuroscience. 13: 397. PMID 31080400 DOI: 10.3389/fnins.2019.00397  0.68
2019 Adewole DO, Serruya MD, Wolf JA, Cullen DK. Bioactive Neuroelectronic Interfaces. Frontiers in Neuroscience. 13: 269. PMID 30983957 DOI: 10.3389/fnins.2019.00269  0.68
2019 Wofford KL, Cullen DK, Spiller KL. Modulation of Macrophage Phenotype via Phagocytosis of Drug-Loaded Microparticles. Journal of Biomedical Materials Research. Part A. PMID 30672109 DOI: 10.1002/jbm.a.36617  0.36
2018 Shen W, Das S, Vitale F, Richardson A, Ananthakrishnan A, Struzyna LA, Brown DP, Song N, Ramkumar M, Lucas T, Cullen DK, Litt B, Allen MG. Microfabricated intracortical extracellular matrix-microelectrodes for improving neural interfaces. Microsystems & Nanoengineering. 4: 30. PMID 31057918 DOI: 10.1038/s41378-018-0030-5  0.64
2018 O'Donnell JC, Browne KD, Kilbaugh TJ, Chen HI, Whyte J, Cullen DK. Challenges and demand for modeling disorders of consciousness following traumatic brain injury. Neuroscience and Biobehavioral Reviews. PMID 30550859 DOI: 10.1016/j.neubiorev.2018.12.015  0.56
2018 Vitale F, Shen W, Driscoll N, Burrell JC, Richardson AG, Adewole O, Murphy B, Ananthakrishnan A, Oh H, Wang T, Lucas TH, Cullen DK, Allen MG, Litt B. Biomimetic extracellular matrix coatings improve the chronic biocompatibility of microfabricated subdural microelectrode arrays. Plos One. 13: e0206137. PMID 30383805 DOI: 10.1371/journal.pone.0206137  0.52
2018 O'Donnell JC, Katiyar KS, Panzer KV, Cullen DK. A tissue-engineered rostral migratory stream for directed neuronal replacement. Neural Regeneration Research. 13: 1327-1331. PMID 30106034 DOI: 10.4103/1673-5374.235215  0.8
2018 Struzyna LA, Browne KD, Brodnik ZD, Burrell JC, Harris JP, Isaac Chen H, Wolf JA, Panzer KV, Lim J, Duda JE, España RA, Kacy Cullen D. Tissue engineered nigrostriatal pathway for treatment of Parkinson's disease. Journal of Tissue Engineering and Regenerative Medicine. PMID 29766664 DOI: 10.1002/term.2698  0.32
2018 Zhang Q, Nguyen PD, Shi S, Burrell JC, Cullen DK, Le AD. 3D bio-printed scaffold-free nerve constructs with human gingiva-derived mesenchymal stem cells promote rat facial nerve regeneration. Scientific Reports. 8: 6634. PMID 29700345 DOI: 10.1038/s41598-018-24888-w  0.52
2018 Johnson VE, Weber MT, Xiao R, Cullen DK, Meaney DF, Stewart W, Smith DH. Mechanical disruption of the blood-brain barrier following experimental concussion. Acta Neuropathologica. PMID 29460006 DOI: 10.1007/s00401-018-1824-0  0.92
2018 Katiyar KS, Winter CC, Gordián-Vélez WJ, O'Donnell JC, Song YJ, Hernandez NS, Struzyna LA, Cullen DK. Three-dimensional Tissue Engineered Aligned Astrocyte Networks to Recapitulate Developmental Mechanisms and Facilitate Nervous System Regeneration. Journal of Visualized Experiments : Jove. PMID 29364269 DOI: 10.3791/55848  0.8
2017 Struzyna LA, Adewole DO, Gordián-Vélez WJ, Grovola MR, Burrell JC, Katiyar KS, Petrov D, Harris JP, Cullen DK. Anatomically Inspired Three-dimensional Micro-tissue Engineered Neural Networks for Nervous System Reconstruction, Modulation, and Modeling. Journal of Visualized Experiments : Jove. PMID 28605376 DOI: 10.3791/55609  0.8
2017 Wolf JA, Johnson BN, Johnson VE, Putt ME, Browne KD, Mietus CJ, Brown DP, Wofford KL, Smith DH, Grady MS, Cohen AS, Cullen DK. Concussion Induces Hippocampal Circuitry Disruption in Swine. Journal of Neurotrauma. PMID 28298170 DOI: 10.1089/neu.2016.4848  0.92
2017 Wofford KL, Harris JP, Browne KD, Brown DP, Grovola MR, Mietus CJ, Wolf JA, Duda JE, Putt ME, Spiller KL, Kacy Cullen D. Rapid Neuroinflammatory Response Localized to Injured Neurons After Diffuse Traumatic Brain Injury in Swine. Experimental Neurology. PMID 28081963 DOI: 10.1016/j.expneurol.2017.01.004  0.48
2016 Roberts SE, Thibaudeau S, Burrell JC, Zager EL, Cullen DK, Levin LS. To reverse or not to reverse? A systematic review of autograft polarity on functional outcomes following peripheral nerve repair surgery. Microsurgery. PMID 27935644 DOI: 10.1002/micr.30133  0.52
2016 Adewole DO, Serruya MD, Harris JP, Burrell JC, Petrov D, Chen HI, Wolf JA, Cullen DK. The Evolution of Neuroprosthetic Interfaces. Critical Reviews in Biomedical Engineering. 44: 123-52. PMID 27652455 DOI: 10.1615/CritRevBiomedEng.2016017198  0.68
2016 Cullen DK, Harris JP, Browne KD, Wolf JA, Duda JE, Meaney DF, Margulies SS, Smith DH. A Porcine Model of Traumatic Brain Injury via Head Rotational Acceleration. Methods in Molecular Biology (Clifton, N.J.). 1462: 289-324. PMID 27604725 DOI: 10.1007/978-1-4939-3816-2_17  0.92
2016 Katiyar KS, Winter CC, Struzyna LA, Harris JP, Cullen DK. Mechanical elongation of astrocyte processes to create living scaffolds for nervous system regeneration. Journal of Tissue Engineering and Regenerative Medicine. PMID 27273796 DOI: 10.1002/term.2168  0.8
2016 Winter CC, Katiyar KS, Hernandez NS, Song YJ, Struzyna LA, Harris JP, Kacy Cullen D. Transplantable living scaffolds comprised of micro-tissue engineered aligned astrocyte networks to facilitate central nervous system regeneration. Acta Biomaterialia. PMID 27090594 DOI: 10.1016/j.actbio.2016.04.021  1
2016 Chen HI, Jgamadze D, Serruya MD, Cullen DK, Wolf JA, Smith DH. Neural Substrate Expansion for the Restoration of Brain Function. Frontiers in Systems Neuroscience. 10: 1. PMID 26834579 DOI: 10.3389/fnsys.2016.00001  1
2016 Harris JP, Struzyna LA, Murphy PL, Adewole DO, Kuo E, Cullen DK. Advanced biomaterial strategies to transplant preformed micro-tissue engineered neural networks into the brain. Journal of Neural Engineering. 13: 016019. PMID 26760138 DOI: 10.1088/1741-2560/13/1/016019  1
2015 Johnson VE, Stewart W, Weber MT, Cullen DK, Siman R, Smith DH. SNTF immunostaining reveals previously undetected axonal pathology in traumatic brain injury. Acta Neuropathologica. PMID 26589592 DOI: 10.1007/s00401-015-1506-0  1
2015 Struzyna LA, Wolf JA, Mietus CJ, Adewole DO, Chen HI, Smith D, Cullen DK. Rebuilding brain circuitry with living micro-tissue engineered neural networks. Tissue Engineering. Part A. PMID 26414439 DOI: 10.1089/ten.TEA.2014.0557  1
2015 Ross JD, Cullen DK, Harris JP, LaPlaca MC, DeWeerth SP. A three-dimensional image processing program for accurate, rapid, and semi-automated segmentation of neuronal somata with dense neurite outgrowth. Frontiers in Neuroanatomy. 9: 87. PMID 26257609 DOI: 10.3389/fnana.2015.00087  1
2015 Struzyna LA, Harris JP, Katiyar KS, Chen HI, Cullen DK. Restoring nervous system structure and function using tissue engineered living scaffolds. Neural Regeneration Research. 10: 679-85. PMID 26109930 DOI: 10.4103/1673-5374.156943  0.8
2015 Johnson VE, Meaney DF, Cullen DK, Smith DH. Animal models of traumatic brain injury. Handbook of Clinical Neurology. 127: 115-28. PMID 25702213 DOI: 10.1016/B978-0-444-52892-6.00008-8  1
2015 Ross JD, Cullen DK, Harris JP, LaPlaca MC, DeWeerth SP. A three-dimensional image processing program for accurate, rapid, and semi-automated segmentation of neuronal somata with dense neurite outgrowth Frontiers in Neuroanatomy. 9. DOI: 10.3389/fnana.2015.00087  1
2014 Struzyna LA, Katiyar K, Cullen DK. Living scaffolds for neuroregeneration. Current Opinion in Solid State & Materials Science. 18: 308-318. PMID 28736499 DOI: 10.1016/j.cossms.2014.07.004  0.64
2014 Struzyna LA, Katiyar K, Cullen DK. Living scaffolds for neuroregeneration Current Opinion in Solid State and Materials Science. 18: 308-318. DOI: 10.1016/j.cossms.2014.07.004  1
2013 Cullen DK, Smith DH. Bionic connections. Scientific American. 308: 52-7. PMID 23342452 DOI: 10.1038/scientificamerican0113-52  1
2013 Meng X, Browne KD, Huang SM, Mietus C, Cullen DK, Tofighi MR, Rosen A. Dynamic evaluation of a digital wireless intracranial pressure sensor for the assessment of traumatic brain injury in a swine model Ieee Transactions On Microwave Theory and Techniques. 61: 316-325. DOI: 10.1109/TMTT.2012.2224361  1
2012 Cullen DK, Tang-Schomer MD, Struzyna LA, Patel AR, Johnson VE, Wolf JA, Smith DH. Microtissue engineered constructs with living axons for targeted nervous system reconstruction. Tissue Engineering. Part A. 18: 2280-9. PMID 22702955 DOI: 10.1089/ten.TEA.2011.0534  0.56
2012 Meng X, Browne K, Huang SM, Cullen DK, Tofighi MR, Rosen A. Dynamic study of wireless intracranial pressure monitoring of rotational head injury in swine model Electronics Letters. 48: 363-364. DOI: 10.1049/el.2012.0281  1
2011 Cullen DK, Browne KD, Xu Y, Adeeb S, Wolf JA, McCarron RM, Yang S, Chavko M, Smith DH. Blast-induced color change in photonic crystals corresponds with brain pathology. Journal of Neurotrauma. 28: 2307-18. PMID 22082449 DOI: 10.1089/neu.2011.1718  1
2011 Cullen DK, Vernekar VN, LaPlaca MC. Trauma-induced plasmalemma disruptions in three-dimensional neural cultures are dependent on strain modality and rate. Journal of Neurotrauma. 28: 2219-33. PMID 22023556 DOI: 10.1089/neu.2011.1841  1
2011 Cullen DK, Wolf JA, Smith DH, Pfister BJ. Neural tissue engineering for neuroregeneration and biohybridized interface microsystems in vivo (Part 2). Critical Reviews in Biomedical Engineering. 39: 241-59. PMID 21967304  0.96
2011 Cullen DK, Wolf JA, Vernekar VN, Vukasinovic J, LaPlaca MC. Neural tissue engineering and biohybridized microsystems for neurobiological investigation in vitro (Part 1). Critical Reviews in Biomedical Engineering. 39: 201-40. PMID 21967303  0.6
2011 Cullen DK, Pfister B. Transformative research in neural engineering: Foreword / editors' commentary (volume 3). Critical Reviews in Biomedical Engineering. 39: 181-3. PMID 21967301  0.6
2011 Higgins AZ, Cullen DK, LaPlaca MC, Karlsson JO. Effects of freezing profile parameters on the survival of cryopreserved rat embryonic neural cells. Journal of Neuroscience Methods. 201: 9-16. PMID 21816171 DOI: 10.1016/j.jneumeth.2011.06.033  1
2011 Pfister BJ, Gordon T, Loverde JR, Kochar AS, Mackinnon SE, Cullen DK. Biomedical engineering strategies for peripheral nerve repair: surgical applications, state of the art, and future challenges. Critical Reviews in Biomedical Engineering. 39: 81-124. PMID 21488817  0.4
2011 Cullen DK, Pfister B. State of the art and future challenges in neural engineering: strategies for nervous system repair foreword / editors' commentary (volume 2). Critical Reviews in Biomedical Engineering. 39: 79-80. PMID 21488816  0.32
2011 Cullen DK, Pfister B. State of the art and future challenges in neural engineering: neural interfaces: foreword / editors' commentary (volume 1). Critical Reviews in Biomedical Engineering. 39: 1-3. PMID 21488811  0.32
2011 Cullen DK, Xu Y, Reneer DV, Browne KD, Geddes JW, Yang S, Smith DH. Color changing photonic crystals detect blast exposure. Neuroimage. 54: S37-44. PMID 21040795 DOI: 10.1016/j.neuroimage.2010.10.076  1
2011 Meng X, Cullen DK, Tofighi MR, Rosen A. Pressure sensing system for the study of blast-induced traumatic brain injury 2011 Ieee 37th Annual Northeast Bioengineering Conference, Nebec 2011. DOI: 10.1109/NEBC.2011.5778619  1
2010 Cullen DK, Gilroy ME, Irons HR, Laplaca MC. Synapse-to-neuron ratio is inversely related to neuronal density in mature neuronal cultures. Brain Research. 1359: 44-55. PMID 20800585 DOI: 10.1016/j.brainres.2010.08.058  1
2009 LaPlaca MC, Prado GR, Cullen D, Simon CM. Plasma membrane damage as a marker of neuronal injury. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 2009: 1113-6. PMID 19964751 DOI: 10.1109/IEMBS.2009.5334457  1
2009 Vukasinovic J, Cullen DK, LaPlaca MC, Glezer A. A microperfused incubator for tissue mimetic 3D cultures. Biomedical Microdevices. 11: 1155-65. PMID 19562488 DOI: 10.1007/s10544-009-9332-6  1
2009 Huang JH, Cullen DK, Browne KD, Groff R, Zhang J, Pfister BJ, Zager EL, Smith DH. Long-term survival and integration of transplanted engineered nervous tissue constructs promotes peripheral nerve regeneration. Tissue Engineering. Part A. 15: 1677-85. PMID 19231968 DOI: 10.1089/ten.tea.2008.0294  1
2009 Vernekar VN, Cullen DK, Fogleman N, Choi Y, García AJ, Allen MG, Brewer GJ, LaPlaca MC. SU-8 2000 rendered cytocompatible for neuronal bioMEMS applications. Journal of Biomedical Materials Research. Part A. 89: 138-51. PMID 18431778 DOI: 10.1002/jbm.a.31839  1
2008 Kameswaran N, Cullen DK, Pfister BJ, Ranalli NJ, Huang JH, Zager EL, Smith DH. A novel neuroprosthetic interface with the peripheral nervous system using artificially engineered axonal tracts. Neurological Research. 30: 1063-7. PMID 19079981 DOI: 10.1179/174313208X362541  0.56
2008 Cullen DK, R Patel A, Doorish JF, Smith DH, Pfister BJ. Developing a tissue-engineered neural-electrical relay using encapsulated neuronal constructs on conducting polymer fibers. Journal of Neural Engineering. 5: 374-84. PMID 18827311 DOI: 10.1088/1741-2560/5/4/002  1
2008 Irons HR, Cullen DK, Shapiro NP, Lambert NA, Lee RH, Laplaca MC. Three-dimensional neural constructs: a novel platform for neurophysiological investigation. Journal of Neural Engineering. 5: 333-41. PMID 18756031 DOI: 10.1088/1741-2560/5/3/006  1
2007 Cullen DK, Stabenfeldt SE, Simon CM, Tate CC, LaPlaca MC. In vitro neural injury model for optimization of tissue-engineered constructs. Journal of Neuroscience Research. 85: 3642-51. PMID 17671988 DOI: 10.1002/jnr.21434  1
2007 LaPlaca MC, Simon CM, Prado GR, Cullen DK. CNS injury biomechanics and experimental models. Progress in Brain Research. 161: 13-26. PMID 17618967 DOI: 10.1016/S0079-6123(06)61002-9  1
2007 Cullen DK, Simon CM, LaPlaca MC. Strain rate-dependent induction of reactive astrogliosis and cell death in three-dimensional neuronal-astrocytic co-cultures. Brain Research. 1158: 103-15. PMID 17555726 DOI: 10.1016/j.brainres.2007.04.070  1
2007 Cullen DK, Vukasinovic J, Glezer A, Laplaca MC. Microfluidic engineered high cell density three-dimensional neural cultures. Journal of Neural Engineering. 4: 159-72. PMID 17409489 DOI: 10.1088/1741-2560/4/2/015  1
2007 Cullen DK, Lessing MC, LaPlaca MC. Collagen-dependent neurite outgrowth and response to dynamic deformation in three-dimensional neuronal cultures. Annals of Biomedical Engineering. 35: 835-46. PMID 17385044 DOI: 10.1007/s10439-007-9292-z  1
2006 LaPlaca MC, Prado GR, Cullen DK, Irons HR. High rate shear insult delivered to cortical neurons produces heterogeneous membrane permeability alterations. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 1: 2384-7. PMID 17946956 DOI: 10.1109/IEMBS.2006.260633  1
2006 Cullen DK, Vukasinovic J, Glezer A, LaPlaca MC. High cell density three-dimensional neural co-cultures require continuous medium perfusion for survival. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 1: 636-9. PMID 17946846 DOI: 10.1109/IEMBS.2006.260639  1
2006 Cullen DK, LaPlaca MC. Neuronal response to high rate shear deformation depends on heterogeneity of the local strain field. Journal of Neurotrauma. 23: 1304-19. PMID 16958583 DOI: 10.1089/neu.2006.23.1304  1
2005 LaPlaca MC, Cullen DK, McLoughlin JJ, Cargill RS. High rate shear strain of three-dimensional neural cell cultures: a new in vitro traumatic brain injury model. Journal of Biomechanics. 38: 1093-105. PMID 15797591 DOI: 10.1016/j.jbiomech.2004.05.032  1
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