David Meaney, Ph.D. - Publications

Bioengineering University of Pennsylvania, Philadelphia, PA, United States 
Biomechanics, Traumatic Brain Injury

119 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Schroeder ME, Bassett DS, Meaney DF. A multilayer network model of neuron-astrocyte populations in vitro reveals mGluR inhibition is protective following traumatic injury. Network Neuroscience (Cambridge, Mass.). 6: 499-527. PMID 35733423 DOI: 10.1162/netn_a_00227  0.341
2022 Billiar K, Gaver DP, Barbee K, Singh A, DesJardins JD, Pruitt B, Tranquillo J, Gaudette G, Winkelstein B, Makowski L, Amos JR, Saterbak A, LeDoux J, Helmke B, Grimm M, ... ... Meaney D, et al. Learning Environments and Evidence-Based Practices in Bioengineering and Biomedical Engineering. Biomedical Engineering Education. 2: 1-16. PMID 35599985 DOI: 10.1007/s43683-021-00062-z  0.632
2022 Shin S, Hefti MM, Mazandi VM, Issadore DA, Meaney D, Christman Schneider ALLC, Diaz-Arrastia R, Kilbaugh TJ. Plasma Neurofilament Light and Glial Fibrillary Acidic Protein Levels over 30 days in a Porcine Model of Traumatic Brain Injury. Journal of Neurotrauma. PMID 35369719 DOI: 10.1089/neu.2022.0070  0.348
2022 Wu T, Rifkin JA, Rayfield A, Panzer MB, Meaney DF. An interdisciplinary computational model for predicting traumatic brain injury: Linking biomechanics and functional neural networks. Neuroimage. 251: 119002. PMID 35176490 DOI: 10.1016/j.neuroimage.2022.119002  0.402
2022 Schumm SN, Gabrieli D, Meaney DF. Plasticity impairment exposes CA3 vulnerability in a hippocampal network model of mild traumatic brain injury. Hippocampus. PMID 34978378 DOI: 10.1002/hipo.23402  0.315
2021 Beard K, Yang Z, Haber M, Flamholz M, Diaz-Arrastia R, Sandsmark D, Meaney DF, Issadore D. Extracellular vesicles as distinct biomarker reservoirs for mild traumatic brain injury diagnosis. Brain Communications. 3: fcab151. PMID 34622206 DOI: 10.1093/braincomms/fcab151  0.362
2021 Mott RE, von Reyn CR, Firestein BL, Meaney DF. Regional Neurodegeneration : The Protective Role of Neural Activity. Frontiers in Computational Neuroscience. 15: 580107. PMID 33854425 DOI: 10.3389/fncom.2021.580107  0.819
2021 Smith DH, Dollé JP, Ameen-Ali KE, Bretzin A, Cortes E, Crary JF, Dams-O'Connor K, Diaz-Arrastia R, Edlow BL, Folkerth R, Hazrati LN, Hinds SR, Iacono D, Johnson VE, Keene CD, ... ... Meaney D, et al. COllaborative Neuropathology NEtwork Characterizing ouTcomes of TBI (CONNECT-TBI). Acta Neuropathologica Communications. 9: 32. PMID 33648593 DOI: 10.1186/s40478-021-01122-9  0.319
2020 Saikumar J, Kim J, Byrns CN, Hemphill M, Meaney DF, Bonini NM. Inducing different severities of traumatic brain injury in Drosophila using a piezoelectric actuator. Nature Protocols. PMID 33277631 DOI: 10.1038/s41596-020-00415-y  0.355
2020 Gabrieli D, Schumm SN, Vigilante NF, Meaney DF. NMDA Receptor Alterations after Mild Traumatic Brain Injury Induce Deficits in Memory Acquisition and Recall. Neural Computation. 1-29. PMID 33253030 DOI: 10.1162/neco_a_01343  0.357
2020 Gabrieli D, Schumm SN, Vigilante NF, Parvesse B, Meaney DF. Neurodegeneration exposes firing rate dependent effects on oscillation dynamics in computational neural networks. Plos One. 15: e0234749. PMID 32966291 DOI: 10.1371/journal.pone.0234749  0.337
2020 Saikumar J, Byrns CN, Hemphill M, Meaney DF, Bonini NM. Dynamic neural and glial responses of a head-specific model for traumatic brain injury in . Proceedings of the National Academy of Sciences of the United States of America. PMID 32611818 DOI: 10.1073/Pnas.2003909117  0.387
2020 Beard K, Meaney D, Issadore DA. Clinical applications of extracellular vesicles in the diagnosis and treatment of traumatic brain injury. Journal of Neurotrauma. PMID 32312151 DOI: 10.1089/Neu.2020.6990  0.302
2019 Omelchenko A, Shrirao AB, Bhattiprolu AK, Zahn JD, Schloss RS, Dickson S, Meaney DF, Boustany NN, Yarmush ML, Firestein BL. Dynamin and reverse-mode sodium calcium exchanger blockade confers neuroprotection from diffuse axonal injury. Cell Death & Disease. 10: 727. PMID 31562294 DOI: 10.1038/S41419-019-1908-3  0.338
2019 Ko J, Hemphill M, Yang Z, Beard K, Sewell E, Shallcross J, Schweizer M, Sandsmark D, Diaz-Arrastia R, Kim J, Meaney D, Issadore DA. Multidimensional mapping of brain-derived extracellular vesicle (EV) miRNA biomarker for traumatic brain injury diagnostics. Journal of Neurotrauma. PMID 30950328 DOI: 10.1089/Neu.2018.6220  0.356
2019 Patel MV, Sewell E, Dickson S, Kim H, Meaney D, Firestein BL. A Role for Postsynaptic Density 95 and its Binding Partners in Models of Traumatic Brain Injury. Journal of Neurotrauma. PMID 30747034 DOI: 10.1089/neu.2018.6291  0.445
2018 Swiatkowski P, Sewell E, Sweet ES, Dickson S, Swanson RA, McEwan SA, Cuccolo N, McDonnell ME, Patel MV, Varghese N, Morrison B, Reitz AB, Meaney DF, Firestein BL. Cypin: A novel target for traumatic brain injury. Neurobiology of Disease. PMID 30031156 DOI: 10.1016/J.Nbd.2018.07.019  0.444
2018 LaPlaca MC, Lessing MC, Prado GR, Zhou R, Tate CC, Geddes-Klein D, Meaney DF, Zhang L. Mechanoporation is a potential indicator of tissue strain and subsequent degeneration following experimental traumatic brain injury. Clinical Biomechanics (Bristol, Avon). PMID 29933966 DOI: 10.1016/J.Clinbiomech.2018.05.016  0.619
2018 DeWitt D, Hawkins BE, Dixon CE, Kochanek PM, Armstead WM, Bass C', Bramlett HM, Büki A, Dietrich WD, Ferguson AR, Hall ED, Hayes RL, Hinds Ii CSR, LaPlaca M, Long J, ... Meaney D, et al. Preclinical Testing of Therapies for Traumatic Brain Injury. Journal of Neurotrauma. PMID 29756522 DOI: 10.1089/Neu.2018.5778  0.723
2018 Johnson VE, Weber MT, Xiao R, Cullen DK, Meaney DF, Stewart W, Smith DH. Mechanical disruption of the blood-brain barrier following experimental concussion. Acta Neuropathologica. PMID 29460006 DOI: 10.1007/S00401-018-1824-0  0.387
2017 Vogel EW, Morales FN, Meaney DF, Bass CR, Morrison B. Phosphodiesterase-4 inhibition restored hippocampal long term potentiation after primary blast. Experimental Neurology. PMID 28366471 DOI: 10.1016/J.Expneurol.2017.03.025  0.381
2016 Cullen DK, Harris JP, Browne KD, Wolf JA, Duda JE, Meaney DF, Margulies SS, Smith DH. A Porcine Model of Traumatic Brain Injury via Head Rotational Acceleration. Methods in Molecular Biology (Clifton, N.J.). 1462: 289-324. PMID 27604725 DOI: 10.1007/978-1-4939-3816-2_17  0.605
2016 Vogel Iii EW, Rwema SH, Meaney D, Bass C', Morrison Iii B. Primary blast injury depressed hippocampal long-term potentiation through disruption of synaptic proteins. Journal of Neurotrauma. PMID 27573357 DOI: 10.1089/neu.2016.4578  0.307
2016 Beamer M, Tummala SR, Gullotti D, Kopil K, Gorka S, Ted Abel, Bass CR, Morrison B, Cohen AS, Meaney DF. Primary blast injury causes cognitive impairments and hippocampal circuit alterations. Experimental Neurology. PMID 27246999 DOI: 10.1016/J.Expneurol.2016.05.025  0.326
2015 Effgen GB, Ong T, Nammalwar S, Ortuno AI, Meaney D, Bass C', Morrison Iii B. Primary blast exposure increases hippocampal vulnerability to subsequent exposure reducing long-term potentiation. Journal of Neurotrauma. PMID 26699926 DOI: 10.1089/neu.2015.4327  0.331
2015 Hue CD, Cho FS, Cao S, Nicholls RE, Vogel Iii EW, Sibindi C, Arancio O, Bass C', Meaney D, Morrison Iii B. Time Course and Size of Blood-Brain Barrier Opening in a Mouse Model of Blast-Induced Traumatic Brain Injury. Journal of Neurotrauma. PMID 26414212 DOI: 10.1089/Neu.2015.4067  0.461
2015 Vogel Iii EW, Effgen GB, Patel T, Bass C', Meaney D, Morrison Iii B. Isolated Primary Blast Inhibits Long-Term Potentiation in Organotypic Hippocampal Slice Cultures. Journal of Neurotrauma. PMID 26414012 DOI: 10.1089/Neu.2015.4045  0.675
2015 Nikolaeva I, Crowell B, Valenziano J, Meaney D, D'Arcangelo G. Beneficial Effects of Early mTORC1 Inhibition after Traumatic Brain Injury. Journal of Neurotrauma. PMID 26122481 DOI: 10.1089/Neu.2015.3899  0.534
2015 Hue CD, Cho FS, Cao S, Dale Bass CR, Meaney DF, Morrison Iii B. Dexamethasone potentiates in vitro blood-brain barrier recovery after primary blast injury by glucocorticoid receptor-mediated upregulation of ZO-1 tight junction protein. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 35: 1191-8. PMID 25757751 DOI: 10.1038/jcbfm.2015.38  0.38
2015 Johnson VE, Meaney DF, Cullen DK, Smith DH. Animal models of traumatic brain injury. Handbook of Clinical Neurology. 127: 115-28. PMID 25702213 DOI: 10.1016/B978-0-444-52892-6.00008-8  0.377
2015 Meaney DF, Smith DH. Cellular biomechanics of central nervous system injury. Handbook of Clinical Neurology. 127: 105-14. PMID 25702212 DOI: 10.1016/B978-0-444-52892-6.00007-6  0.355
2015 Patel TP, Man K, Firestein BL, Meaney DF. Automated quantification of neuronal networks and single-cell calcium dynamics using calcium imaging. Journal of Neuroscience Methods. 243: 26-38. PMID 25629800 DOI: 10.1016/J.Jneumeth.2015.01.020  0.618
2015 Kang WH, Cao W, Graudejus O, Patel TP, Wagner S, Meaney DF, Morrison B. Alterations in Hippocampal Network Activity after In Vitro Traumatic Brain Injury. Journal of Neurotrauma. 32: 1011-9. PMID 25517970 DOI: 10.1089/Neu.2014.3667  0.702
2015 Meaney DF. Biomechanics of brain injury: Looking to the future Accidental Injury: Biomechanics and Prevention. 247-257. DOI: 10.1007/978-1-4939-1732-7_10  0.384
2014 Patel TP, Gullotti DM, Hernandez P, O'Brien WT, Capehart BP, Morrison B, Bass C, Eberwine JE, Abel T, Meaney DF. An open-source toolbox for automated phenotyping of mice in behavioral tasks. Frontiers in Behavioral Neuroscience. 8: 349. PMID 25339878 DOI: 10.3389/Fnbeh.2014.00349  0.61
2014 Chen Y, Mao H, Yang KH, Abel T, Meaney DF. A modified controlled cortical impact technique to model mild traumatic brain injury mechanics in mice. Frontiers in Neurology. 5: 100. PMID 24994996 DOI: 10.3389/Fneur.2014.00100  0.405
2014 Gullotti DM, Beamer M, Panzer MB, Chen YC, Patel TP, Yu A, Jaumard N, Winkelstein B, Bass CR, Morrison B, Meaney DF. Significant head accelerations can influence immediate neurological impairments in a murine model of blast-induced traumatic brain injury. Journal of Biomechanical Engineering. 136: 091004. PMID 24950710 DOI: 10.1115/1.4027873  0.687
2014 Patel TP, Ventre SC, Geddes-Klein D, Singh PK, Meaney DF. Single-neuron NMDA receptor phenotype influences neuronal rewiring and reintegration following traumatic injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 4200-13. PMID 24647941 DOI: 10.1523/Jneurosci.4172-13.2014  0.804
2014 Effgen GB, Vogel EW, Lynch KA, Lobel A, Hue CD, Meaney DF, Bass CR, Morrison B. Isolated primary blast alters neuronal function with minimal cell death in organotypic hippocampal slice cultures. Journal of Neurotrauma. 31: 1202-10. PMID 24558968 DOI: 10.1089/Neu.2013.3227  0.446
2014 Meaney DF, Morrison B, Dale Bass C. The mechanics of traumatic brain injury: a review of what we know and what we need to know for reducing its societal burden. Journal of Biomechanical Engineering. 136: 021008. PMID 24384610 DOI: 10.1115/1.4026364  0.386
2014 Hue CD, Cao S, Dale Bass CR, Meaney DF, Morrison B. Repeated primary blast injury causes delayed recovery, but not additive disruption, in an in vitro blood-brain barrier model. Journal of Neurotrauma. 31: 951-60. PMID 24372353 DOI: 10.1089/Neu.2013.3149  0.444
2013 Weerakkody TN, Patel TP, Yue C, Takano H, Anderson HC, Meaney DF, Coulter DA, Wolfe JH. Engraftment of nonintegrating neural stem cells differentially perturbs cortical activity in a dose-dependent manner. Molecular Therapy : the Journal of the American Society of Gene Therapy. 21: 2258-67. PMID 23831593 DOI: 10.1038/Mt.2013.163  0.606
2013 Hue CD, Cao S, Haider SF, Vo KV, Effgen GB, Vogel E, Panzer MB, Bass CR, Meaney DF, Morrison B. Blood-brain barrier dysfunction after primary blast injury in vitro. Journal of Neurotrauma. 30: 1652-63. PMID 23581482 DOI: 10.1089/Neu.2012.2773  0.471
2013 Schoch KM, von Reyn CR, Bian J, Telling GC, Meaney DF, Saatman KE. Brain injury-induced proteolysis is reduced in a novel calpastatin-overexpressing transgenic mouse. Journal of Neurochemistry. 125: 909-20. PMID 23305291 DOI: 10.1111/Jnc.12144  0.839
2013 Choo AM, Miller WJ, Chen YC, Nibley P, Patel TP, Goletiani C, Morrison B, Kutzing MK, Firestein BL, Sul JY, Haydon PG, Meaney DF. Antagonism of purinergic signalling improves recovery from traumatic brain injury. Brain : a Journal of Neurology. 136: 65-80. PMID 23293266 DOI: 10.1093/Brain/Aws286  0.73
2012 Mesfin MN, von Reyn CR, Mott RE, Putt ME, Meaney DF. In vitro stretch injury induces time- and severity-dependent alterations of STEP phosphorylation and proteolysis in neurons. Journal of Neurotrauma. 29: 1982-98. PMID 22435660 DOI: 10.1089/Neu.2011.2253  0.801
2012 von Reyn CR, Mott RE, Siman R, Smith DH, Meaney DF. Mechanisms of calpain mediated proteolysis of voltage gated sodium channel α-subunits following in vitro dynamic stretch injury. Journal of Neurochemistry. 121: 793-805. PMID 22428606 DOI: 10.1111/J.1471-4159.2012.07735.X  0.837
2012 Spaethling J, Le L, Meaney DF. NMDA receptor mediated phosphorylation of GluR1 subunits contributes to the appearance of calcium-permeable AMPA receptors after mechanical stretch injury. Neurobiology of Disease. 46: 646-54. PMID 22426393 DOI: 10.1016/J.Nbd.2012.03.003  0.826
2012 Effgen GB, Hue CD, Vogel E, Panzer MB, Meaney DF, Bass CR, Morrison B. A Multiscale Approach to Blast Neurotrauma Modeling: Part II: Methodology for Inducing Blast Injury to in vitro Models. Frontiers in Neurology. 3: 23. PMID 22375134 DOI: 10.3389/fneur.2012.00023  0.377
2012 Choo AM, Geddes-Klein DM, Hockenberry A, Scarsella D, Mesfin MN, Singh P, Patel TP, Meaney DF. NR2A and NR2B subunits differentially mediate MAP kinase signaling and mitochondrial morphology following excitotoxic insult. Neurochemistry International. 60: 506-16. PMID 22366650 DOI: 10.1016/J.Neuint.2012.02.007  0.789
2012 Singh P, Doshi S, Spaethling JM, Hockenberry AJ, Patel TP, Geddes-Klein DM, Lynch DR, Meaney DF. N-methyl-D-aspartate receptor mechanosensitivity is governed by C terminus of NR2B subunit. The Journal of Biological Chemistry. 287: 4348-59. PMID 22179603 DOI: 10.1074/Jbc.M111.253740  0.8
2012 Patel TP, Ventre SC, Meaney DF. Dynamic changes in neural circuit topology following mild mechanical injury in vitro. Annals of Biomedical Engineering. 40: 23-36. PMID 21994056 DOI: 10.1007/S10439-011-0390-6  0.703
2012 Ji J, Tyurina YY, Tang M, Feng W, Stolz DB, Clark RS, Meaney DF, Kochanek PM, Kagan VE, Bay?r H. Mitochondrial injury after mechanical stretch of cortical neurons in vitro: biomarkers of apoptosis and selective peroxidation of anionic phospholipids. Journal of Neurotrauma. 29: 776-88. PMID 21895519 DOI: 10.1089/Neu.2010.1602  0.32
2011 LaPlaca MC, Meaney DF. Perspectives on the role of bioengineering in neurotrauma research. Journal of Neurotrauma. 28: 2201-2. PMID 22082448 DOI: 10.1089/neu.2011.9944  0.502
2011 Volpicelli-Daley LA, Luk KC, Patel TP, Tanik SA, Riddle DM, Stieber A, Meaney DF, Trojanowski JQ, Lee VM. Exogenous α-synuclein fibrils induce Lewy body pathology leading to synaptic dysfunction and neuron death. Neuron. 72: 57-71. PMID 21982369 DOI: 10.1016/J.Neuron.2011.08.033  0.608
2011 Browne KD, Chen XH, Meaney DF, Smith DH. Mild traumatic brain injury and diffuse axonal injury in swine. Journal of Neurotrauma. 28: 1747-55. PMID 21740133 DOI: 10.1089/Neu.2011.1913  0.325
2011 Singh P, Hockenberry AJ, Tiruvadi VR, Meaney DF. Computational investigation of the changing patterns of subtype specific NMDA receptor activation during physiological glutamatergic neurotransmission. Plos Computational Biology. 7: e1002106. PMID 21738464 DOI: 10.1371/Journal.Pcbi.1002106  0.586
2011 Meaney DF, Smith DH. Biomechanics of concussion. Clinics in Sports Medicine. 30: 19-31, vii. PMID 21074079 DOI: 10.1016/J.Csm.2010.08.009  0.372
2009 von Reyn CR, Spaethling JM, Mesfin MN, Ma M, Neumar RW, Smith DH, Siman R, Meaney DF. Calpain mediates proteolysis of the voltage-gated sodium channel alpha-subunit. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 10350-6. PMID 19692609 DOI: 10.1523/Jneurosci.2339-09.2009  0.783
2009 Chen YC, Smith DH, Meaney DF. In-vitro approaches for studying blast-induced traumatic brain injury. Journal of Neurotrauma. 26: 861-76. PMID 19397424 DOI: 10.1089/Neu.2008.0645  0.371
2009 Sul JY, Wu CW, Zeng F, Jochems J, Lee MT, Kim TK, Peritz T, Buckley P, Cappelleri DJ, Maronski M, Kim M, Kumar V, Meaney D, Kim J, Eberwine J. Transcriptome transfer produces a predictable cellular phenotype. Proceedings of the National Academy of Sciences of the United States of America. 106: 7624-9. PMID 19380745 DOI: 10.1073/Pnas.0902161106  0.311
2009 Miller WJ, Leventhal I, Scarsella D, Haydon PG, Janmey P, Meaney DF. Mechanically induced reactive gliosis causes ATP-mediated alterations in astrocyte stiffness. Journal of Neurotrauma. 26: 789-97. PMID 19331521 DOI: 10.1089/Neu.2008.0727  0.397
2009 Ma M, Matthews BT, Lampe JW, Meaney DF, Shofer FS, Neumar RW. Immediate short-duration hypothermia provides long-term protection in an in vivo model of traumatic axonal injury. Experimental Neurology. 215: 119-27. PMID 18977220 DOI: 10.1016/J.Expneurol.2008.09.024  0.308
2008 Spaethling JM, Klein DM, Singh P, Meaney DF. Calcium-permeable AMPA receptors appear in cortical neurons after traumatic mechanical injury and contribute to neuronal fate. Journal of Neurotrauma. 25: 1207-16. PMID 18986222 DOI: 10.1089/Neu.2008.0532  0.843
2008 Zhang J, Groff RF, Chen XH, Browne KD, Huang J, Schwartz ED, Meaney DF, Johnson VE, Stein SC, Rojkjaer R, Smith DH. Hemostatic and neuroprotective effects of human recombinant activated factor VII therapy after traumatic brain injury in pigs. Experimental Neurology. 210: 645-55. PMID 18291370 DOI: 10.1016/J.Expneurol.2007.12.019  0.403
2007 Spaethling JM, Geddes-Klein DM, Miller WJ, von Reyn CR, Singh P, Mesfin M, Bernstein SJ, Meaney DF. Linking impact to cellular and molecular sequelae of CNS injury: modeling in vivo complexity with in vitro simplicity. Progress in Brain Research. 161: 27-39. PMID 17618968 DOI: 10.1016/S0079-6123(06)61003-0  0.773
2007 Ma M, Matthews B, Meaney D, Neumar R. Early Calpain Activity in a Rat Model of Traumatic Axonal Injury Academic Emergency Medicine. 14: S35-S36. DOI: 10.1197/J.Aem.2007.03.788  0.304
2006 Geddes-Klein DM, Serbest G, Mesfin MN, Cohen AS, Meaney DF. Pharmacologically induced calcium oscillations protect neurons from increases in cytosolic calcium after trauma. Journal of Neurochemistry. 97: 462-74. PMID 16539664 DOI: 10.1111/J.1471-4159.2006.03761.X  0.807
2006 Geddes-Klein DM, Schiffman KB, Meaney DF. Mechanisms and consequences of neuronal stretch injury in vitro differ with the model of trauma. Journal of Neurotrauma. 23: 193-204. PMID 16503803 DOI: 10.1089/neu.2006.23.193  0.459
2006 DeRidder MN, Simon MJ, Siman R, Auberson YP, Raghupathi R, Meaney DF. Traumatic mechanical injury to the hippocampus in vitro causes regional caspase-3 and calpain activation that is influenced by NMDA receptor subunit composition. Neurobiology of Disease. 22: 165-76. PMID 16356733 DOI: 10.1016/J.Nbd.2005.10.011  0.825
2005 Longhi L, Saatman KE, Fujimoto S, Raghupathi R, Meaney DF, Davis J, McMillan B S A, Conte V, Laurer HL, Stein S, Stocchetti N, McIntosh TK. Temporal window of vulnerability to repetitive experimental concussive brain injury. Neurosurgery. 56: 364-74; discussion 3. PMID 15670384 DOI: 10.1227/01.Neu.0000149008.73513.44  0.639
2005 Meaney DF, Grady MS. Should corticosteroids be used to treat traumatic brain injury? Nature Clinical Practice Neurology. 1: 74-75. DOI: 10.1038/ncpneuro0048  0.387
2005 DeRidder M, Meaney DF. Cellular basis for the nonlinear constitutive properties of brain tissue Solid Mechanics and Its Applications. 124: 291-304.  0.755
2004 Lusardi TA, Rangan J, Sun D, Smith DH, Meaney DF. A device to study the initiation and propagation of calcium transients in cultured neurons after mechanical stretch. Annals of Biomedical Engineering. 32: 1546-58. PMID 15636114 DOI: 10.1114/B:Abme.0000049038.75368.75  0.744
2004 Davis JE, Eberwine JH, Hinkle DA, Marciano PG, Meaney DF, McIntosh TK. Methodological considerations regarding single-cell gene expression profiling for brain injury. Neurochemical Research. 29: 1113-21. PMID 15176468 DOI: 10.1023/B:NERE.0000023598.04937.83  0.343
2004 Iwata A, Stys PK, Wolf JA, Chen XH, Taylor AG, Meaney DF, Smith DH. Traumatic axonal injury induces proteolytic cleavage of the voltage-gated sodium channels modulated by tetrodotoxin and protease inhibitors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 4605-13. PMID 15140932 DOI: 10.1523/Jneurosci.0515-03.2004  0.314
2004 Lusardi TA, Wolf JA, Putt ME, Smith DH, Meaney DF. Effect of acute calcium influx after mechanical stretch injury in vitro on the viability of hippocampal neurons. Journal of Neurotrauma. 21: 61-72. PMID 14987466 DOI: 10.1089/089771504772695959  0.754
2003 Saatman KE, Abai B, Grosvenor A, Vorwerk CK, Smith DH, Meaney DF. Traumatic axonal injury results in biphasic calpain activation and retrograde transport impairment in mice. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 23: 34-42. PMID 12500089 DOI: 10.1097/01.Wcb.0000035040.10031.B0  0.612
2003 Lusardi TA, Smith DH, Wolf JA, Meaney DF. The separate roles of calcium and mechanical forces in mediating cell death in mechanically injured neurons. Biorheology. 40: 401-9. PMID 12454433  0.727
2002 Marciano PG, Eberwine JH, Ragupathi R, Saatman KE, Meaney DF, McIntosh TK. Expression profiling following traumatic brain injury: a review. Neurochemical Research. 27: 1147-55. PMID 12462413 DOI: 10.1023/A:1020973308941  0.648
2001 Meaney DF, Margulies SS, Smith DH. Diffuse axonal injury. Journal of Neurosurgery. 95: 1108-10. PMID 11765833  0.538
2001 Bain AC, Raghupathi R, Meaney DF. Dynamic stretch correlates to both morphological abnormalities and electrophysiological impairment in a model of traumatic axonal injury. Journal of Neurotrauma. 18: 499-511. PMID 11393253 DOI: 10.1089/089771501300227305  0.351
2001 Wolf JA, Stys PK, Lusardi T, Meaney D, Smith DH. Traumatic axonal injury induces calcium influx modulated by tetrodotoxin-sensitive sodium channels. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 1923-30. PMID 11245677 DOI: 10.1523/Jneurosci.21-06-01923.2001  0.739
2001 DeRidder MN, Grosvenor AE, Morrison B, Meaney DF. Mechanical deformation of organotypic cultures induces cell death via both apoptosis and necrosis pathways American Society of Mechanical Engineers, Bioengineering Division (Publication) Bed. 50: 889-890.  0.76
2001 Lusardi TA, Smith DH, Wolf JA, DeRidder MN, Meaney DF. Mechanical stretch of cultured neurons: Relationships between acute cytosolic calcium changes and cell death American Society of Mechanical Engineers, Bioengineering Division (Publication) Bed. 50: 615-616.  0.774
2000 Prange MT, Meaney DF, Margulies SS. Defining brain mechanical properties: effects of region, direction, and species. Stapp Car Crash Journal. 44: 205-13. PMID 17458728 DOI: 10.4271/2000-01-Sc15  0.517
2000 Bain AC, Meaney DF. Tissue-level thresholds for axonal damage in an experimental model of central nervous system white matter injury. Journal of Biomechanical Engineering. 122: 615-22. PMID 11192383 DOI: 10.1115/1.1324667  0.303
2000 Smith FM, Raghupathi R, MacKinnon MA, McIntosh TK, Saatman KE, Meaney DF, Graham DI. TUNEL-positive staining of surface contusions after fatal head injury in man. Acta Neuropathologica. 100: 537-45. PMID 11045676 DOI: 10.1007/S004010000222  0.667
2000 Morrison B, Meaney DF, Margulies SS, McIntosh TK. Dynamic mechanical stretch of organotypic brain slice cultures induces differential genomic expression: relationship to mechanical parameters. Journal of Biomechanical Engineering. 122: 224-30. PMID 10923289 DOI: 10.1115/1.429650  0.519
2000 Morrison B, Eberwine JH, Meaney DF, McIntosh TK. Traumatic injury induces differential expression of cell death genes in organotypic brain slice cultures determined by complementary DNA array hybridization. Neuroscience. 96: 131-9. PMID 10683418 DOI: 10.1016/S0306-4522(99)00537-0  0.386
2000 Graham DI, Raghupathi R, Saatman KE, Meaney D, McIntosh TK. Tissue tears in the white matter after lateral fluid percussion brain injury in the rat: relevance to human brain injury. Acta Neuropathologica. 99: 117-24. PMID 10672317 DOI: 10.1007/Pl00007414  0.687
1999 Smith DH, Chen XH, Nonaka M, Trojanowski JQ, Lee VM, Saatman KE, Leoni MJ, Xu BN, Wolf JA, Meaney DF. Accumulation of amyloid beta and tau and the formation of neurofilament inclusions following diffuse brain injury in the pig. Journal of Neuropathology and Experimental Neurology. 58: 982-92. PMID 10499440  0.607
1999 Chen XH, Meaney DF, Xu BN, Nonaka M, McIntosh TK, Wolf JA, Saatman KE, Smith DH. Evolution of neurofilament subtype accumulation in axons following diffuse brain injury in the pig. Journal of Neuropathology and Experimental Neurology. 58: 588-96. PMID 10374749 DOI: 10.1097/00005072-199906000-00003  0.567
1999 Smith DH, Wolf JA, Lusardi TA, Lee VM, Meaney DF. High tolerance and delayed elastic response of cultured axons to dynamic stretch injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 4263-9. PMID 10341230 DOI: 10.1523/Jneurosci.19-11-04263.1999  0.735
1999 Shreiber DI, Bain AC, Ross DT, Smith DH, Gennarelli TA, McIntosh TK, Meaney DF. Experimental investigation of cerebral contusion: histopathological and immunohistochemical evaluation of dynamic cortical deformation. Journal of Neuropathology and Experimental Neurology. 58: 153-64. PMID 10029098 DOI: 10.1097/00005072-199902000-00005  0.395
1999 Shreiber DI, Smith DH, Meaney DF. Immediate in vivo response of the cortex and the blood-brain barrier following dynamic cortical deformation in the rat. Neuroscience Letters. 259: 5-8. PMID 10027542 DOI: 10.1016/S0304-3940(98)00853-2  0.377
1999 Miller RT, Smith DH, Chen X, Xu BN, Leoni M, Nonaka M, Meaney DF. Comparing experimental data to traumatic brain injury finite element models Stapp Car Crash Conference Proceedings. 303-311. DOI: 10.4271/99Sc20  0.314
1999 Lusardi TA, Meaney DF. Strain dependent channel activation in cultured neurons Annual International Conference of the Ieee Engineering in Medicine and Biology - Proceedings. 1: 36.  0.679
1999 Bain AC, Meaney DF. Thresholds for mechanical injury to the in vivo white matter Stapp Car Crash Conference Proceedings. 295-302.  0.348
1998 Morrison B, Saatman KE, Meaney DF, McIntosh TK. In vitro central nervous system models of mechanically induced trauma: a review. Journal of Neurotrauma. 15: 911-28. PMID 9840765 DOI: 10.1089/Neu.1998.15.911  0.688
1998 Cecil KM, Lenkinski RE, Meaney DF, McIntosh TK, Smith DH. High-field proton magnetic resonance spectroscopy of a swine model for axonal injury. Journal of Neurochemistry. 70: 2038-44. PMID 9572290 DOI: 10.1046/J.1471-4159.1998.70052038.X  0.325
1998 Morrison B, Meaney DF, McIntosh TK. Mechanical characterization of an in vitro device designed to quantitatively injure living brain tissue. Annals of Biomedical Engineering. 26: 381-90. PMID 9570221 DOI: 10.1114/1.61  0.338
1998 Miller RT, Margulies SS, Leoni M, Nonaka M, Chen X, Smith DH, Meaney DF. Finite element modeling approaches for predicting injury in an experimental model of severe diffuse axonal injury Sae Technical Papers. DOI: 10.4271/983154  0.563
1998 Lusardi TA, Wolf J, Smith DH, Meaney DF. Strain and strain rate dependent changes in cytosolic calcium of cultured neurons subjected to mechanical stretch American Society of Mechanical Engineers, Bioengineering Division (Publication) Bed. 40: 61-65.  0.678
1998 Bain AC, Meaney DF. Microstructural kinematics during elongation of central nervous system tissue: Implications for traumatic axonal injury American Society of Mechanical Engineers, Bioengineering Division (Publication) Bed. 39: 153-154.  0.306
1997 Smith DH, Chen XH, Xu BN, McIntosh TK, Gennarelli TA, Meaney DF. Characterization of diffuse axonal pathology and selective hippocampal damage following inertial brain trauma in the pig. Journal of Neuropathology and Experimental Neurology. 56: 822-34. PMID 9210879 DOI: 10.1097/00005072-199756070-00009  0.345
1996 McIntosh TK, Smith DH, Meaney DF, Kotapka MJ, Gennarelli TA, Graham DI. Neuropathological sequelae of traumatic brain injury: relationship to neurochemical and biomechanical mechanisms. Laboratory Investigation; a Journal of Technical Methods and Pathology. 74: 315-42. PMID 8780153  0.412
1996 Smith D, Meaney D, Lenkinski R. New magnetic resonance imaging techniques for the evaluation of traumatic brain injury Journal of Head Trauma Rehabilitation. 11: 100-101. DOI: 10.1097/00001199-199612000-00015  0.38
1995 Meaney DF, Smith DH, Shreiber DI, Bain AC, Miller RT, Ross DT, Gennarelli TA. Biomechanical analysis of experimental diffuse axonal injury. Journal of Neurotrauma. 12: 689-94. PMID 8683620 DOI: 10.1089/Neu.1995.12.689  0.365
1995 Smith DH, Soares HD, Pierce JS, Perlman KG, Saatman KE, Meaney DF, Dixon CE, McIntosh TK. A model of parasagittal controlled cortical impact in the mouse: cognitive and histopathologic effects. Journal of Neurotrauma. 12: 169-78. PMID 7629863 DOI: 10.1089/Neu.1995.12.169  0.684
1995 Landsman AS, Meaney DF, Cargill RS, Macarak EJ, Thibault LE. 1995 William J. Stickel Gold Award. High strain rate tissue deformation. A theory on the mechanical etiology of diabetic foot ulcerations. Journal of the American Podiatric Medical Association. 85: 519-27. PMID 7473083 DOI: 10.7547/87507315-85-10-519  0.755
1995 Arbogast KB, Meaney DF, Thibault LE. Biomechanical characterization of the constitutive relationship for the brainstem Sae Technical Papers. DOI: 10.4271/952716  0.559
1994 Ross DT, Meaney DF, Sabol MK, Smith DH, Gennarelli TA. Distribution of forebrain diffuse axonal injury following inertial closed head injury in miniature swine. Experimental Neurology. 126: 291-9. PMID 7925827 DOI: 10.1006/Exnr.1994.1067  0.345
1994 Meaney DF, Ross DT, Winkelstein BA, Brasko J, Goldstein D, Bilston LB, Thibault LE, Gennarelli TA. Modification of the cortical impact model to produce axonal injury in the rat cerebral cortex. Journal of Neurotrauma. 11: 599-612. PMID 7861451 DOI: 10.1089/Neu.1994.11.599  0.672
1993 Meaney DF, Smith D, Ross DT, Gennarelli TA. Diffuse axonal injury in the miniature pig: Biomechanical development and injury threshold American Society of Mechanical Engineers, Applied Mechanics Division, Amd. 169: 169-175.  0.319
1992 Thibault LE, Meaney DF, Anderson BJ, Marmarou A. Biomechanical aspects of a fluid percussion model of brain injury. Journal of Neurotrauma. 9: 311-22. PMID 1291691 DOI: 10.1089/Neu.1992.9.311  0.659
1992 Saatman KE, Thibault LE, Meaney DF. Biomechanics of isolated myelinated nerve as related to brain injury American Society of Mechanical Engineers, Bioengineering Division (Publication) Bed. 22: 549-552.  0.751
1992 Bilston LB, Meaney DF, Thibault LE. Modeling the mechanical behavior of the cervical spinal cord American Society of Mechanical Engineers, Bioengineering Division (Publication) Bed. 22: 71-74.  0.56
1992 Landsman AS, Thibault LE, Meaney DF, Cargill RS. New system to study mechanical deformation and the resultant calcium transients in endothelial cells American Society of Mechanical Engineers, Bioengineering Division (Publication) Bed. 22: 9-12.  0.766
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