Zhili Huang - Publications

Affiliations: 
Pharmacology Fudan university, Shanghai, Shanghai Shi, China 

133 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Chen Y, Xie WY, Xia D, Zhang MT, Sun YR, Duan WX, Shen Y, Wang F, Qu WM, Huang ZL, Liu CF. GBA-AAV mitigates sleep disruptions and motor deficits in mice with REM sleep behavior disorder. Npj Parkinson's Disease. 10: 142. PMID 39095359 DOI: 10.1038/s41531-024-00756-5  0.477
2024 Pan G, Zhao B, Zhang M, Guo Y, Yan Y, Dai D, Zhang X, Yang H, Ni J, Huang Z, Li X, Duan S. Nucleus Accumbens Corticotropin-Releasing Hormone Neurons Projecting to the Bed Nucleus of the Stria Terminalis Promote Wakefulness and Positive Affective State. Neuroscience Bulletin. PMID 38980648 DOI: 10.1007/s12264-024-01233-y  0.315
2024 Li YD, Luo YJ, Su WK, Ge J, Crowther A, Chen ZK, Wang L, Lazarus M, Liu ZL, Qu WM, Huang ZL. Anterior cingulate cortex projections to the dorsal medial striatum underlie insomnia associated with chronic pain. Neuron. PMID 38354737 DOI: 10.1016/j.neuron.2024.01.014  0.349
2024 Zhou X, He Y, Xu T, Wu Z, Guo W, Xu X, Liu Y, Zhang Y, Shang H, Huang L, Yao Z, Li Z, Su L, Li Z, Feng T, ... ... Huang ZL, et al. 40 Hz light flickering promotes sleep through cortical adenosine signaling. Cell Research. PMID 38332199 DOI: 10.1038/s41422-023-00920-1  0.5
2024 Xiong Y, Zhu J, He Y, Qu W, Huang Z, Ding F. Sleep fragmentation reduces explorative behaviors and impairs motor coordination in male mice. Journal of Neuroscience Research. 102: e25268. PMID 38284850 DOI: 10.1002/jnr.25268  0.473
2024 Fei CJ, Li ZY, Ning J, Yang L, Wu BS, Kang JJ, Liu WS, He XY, You J, Chen SD, Yu H, Huang ZL, Feng JF, Yu JT, Cheng W. Exome sequencing identifies genes associated with sleep-related traits. Nature Human Behaviour. PMID 38177695 DOI: 10.1038/s41562-023-01785-5  0.449
2023 Zhang W, Yu M, Xu Y, Li X, Zuo H, Huang Z, Gao X. Self-reported sleep status and influencing factors: a web-based national cross-sectional survey in China. Annals of Medicine. 55: 2287706. PMID 38048387 DOI: 10.1080/07853890.2023.2287706  0.437
2023 Yao Z, Zhang BX, Chen H, Jiang XW, Qu WM, Huang ZL. Acute or Chronic Exposure to Corticosterone Promotes Wakefulness in Mice. Brain Sciences. 13. PMID 37891839 DOI: 10.3390/brainsci13101472  0.507
2023 Guo H, Jiang JB, Xu W, Zhang MT, Chen H, Shi HY, Wang L, He M, Lazarus M, Li SQ, Huang ZL, Qu WM. Parasubthalamic calretinin neurons modulate wakefulness associated with exploration in male mice. Nature Communications. 14: 2346. PMID 37095092 DOI: 10.1038/s41467-023-37797-y  0.438
2023 Ma WX, Yuan PC, Zhang H, Kong LX, Lazarus M, Qu WM, Wang YQ, Huang ZL. Adenosine and P1 receptors: Key targets in the regulation of sleep, torpor, and hibernation. Frontiers in Pharmacology. 14: 1098976. PMID 36969831 DOI: 10.3389/fphar.2023.1098976  0.443
2023 Bao WW, Jiang S, Qu WM, Li WX, Miao CH, Huang ZL. Understanding the neural mechanisms of general anesthesia from interaction with sleep-wake state: a decade of discovery. Pharmacological Reviews. PMID 36627210 DOI: 10.1124/pharmrev.122.000717  0.456
2022 Zhao YN, Jiang JB, Tao SY, Zhang Y, Chen ZK, Qu WM, Huang ZL, Yang SR. GABAergic neurons in the rostromedial tegmental nucleus are essential for rapid eye movement sleep suppression. Nature Communications. 13: 7552. PMID 36477665 DOI: 10.1038/s41467-022-35299-x  0.533
2022 Chen ZK, Dong H, Liu CW, Liu WY, Zhao YN, Xu W, Sun X, Xiong YY, Liu YY, Yuan XS, Wang B, Lazarus M, Chérasse Y, Li YD, Han F, ... ... Huang ZL, et al. A cluster of mesopontine GABAergic neurons suppresses REM sleep and curbs cataplexy. Cell Discovery. 8: 115. PMID 36280664 DOI: 10.1038/s41421-022-00456-5  0.52
2022 Shen YC, Sun X, Li L, Zhang HY, Huang ZL, Wang YQ. Roles of Neuropeptides in Sleep-Wake Regulation. International Journal of Molecular Sciences. 23. PMID 35562990 DOI: 10.3390/ijms23094599  0.52
2022 Li L, Zhang MQ, Sun X, Liu WY, Huang ZL, Wang YQ. Role of Dorsomedial Hypothalamus GABAergic Neurons in Sleep-Wake States in Response to Changes in Ambient Temperature in Mice. International Journal of Molecular Sciences. 23. PMID 35163194 DOI: 10.3390/ijms23031270  0.508
2022 Dong H, Chen ZK, Guo H, Yuan XS, Liu CW, Qu WM, Huang ZL. Striatal neurons expressing dopamine D receptor promote wakefulness in mice. Current Biology : Cb. PMID 35021048 DOI: 10.1016/j.cub.2021.12.026  0.432
2021 Ba L, Huang L, He Z, Deng S, Xie Y, Zhang M, Jacob C, Antonecchia E, Liu Y, Xiao W, Xie Q, Huang Z, Yi C, D'Ascenzo N, Ding F. Does Chronic Sleep Fragmentation Lead to Alzheimer's Disease in Young Wild-Type Mice? Frontiers in Aging Neuroscience. 13: 759983. PMID 34992526 DOI: 10.3389/fnagi.2021.759983  0.35
2021 Chen CR, Zhong YH, Jiang S, Xu W, Xiao L, Wang Z, Qu WM, Huang ZL. Dysfunctions of the paraventricular hypothalamic nucleus induce hypersomnia in mice. Elife. 10. PMID 34787078 DOI: 10.7554/eLife.69909  0.424
2021 Huang J, Song P, Hang K, Chen Z, Zhu Z, Zhang Y, Xu J, Qin J, Wang B, Qu W, Huang Z, Liang C. Sleep Deprivation Disturbs Immune Surveillance and Promotes the Progression of Hepatocellular Carcinoma. Frontiers in Immunology. 12: 727959. PMID 34539666 DOI: 10.3389/fimmu.2021.727959  0.349
2021 Hao SM, Zhong ZG, Qu WM, Huang ZL, Sun FY, Qiu MH. Melatonin supplementation in the subacute phase after ischemia alleviates postischemic sleep disturbances in rats. Brain and Behavior. e32366. PMID 34520636 DOI: 10.1002/brb3.2366  0.376
2021 Zhong YH, Jiang S, Qu WM, Zhang W, Huang ZL, Chen CR. Saikosaponin a promotes sleep by decreasing neuronal activities in the lateral hypothalamus. Journal of Sleep Research. e13484. PMID 34510626 DOI: 10.1111/jsr.13484  0.525
2021 Sun X, Li L, Zhang HY, He W, Wang DR, Huang ZL, Wang YQ. Adenosine A Receptor Neurons in the Olfactory Bulb Mediate Odor-Guided Behaviors in Miceg. Brain Research. 147590. PMID 34310936 DOI: 10.1016/j.brainres.2021.147590  0.331
2021 Wang YQ, Liu WY, Li L, Qu WM, Huang ZL. Neural circuitry underlying REM sleep: A review of the literature and current concepts. Progress in Neurobiology. 102106. PMID 34144122 DOI: 10.1016/j.pneurobio.2021.102106  0.487
2021 Xu Q, Wang DR, Dong H, Chen L, Lu J, Lazarus M, Cherasse Y, Chen GH, Qu WM, Huang ZL. Medial Parabrachial Nucleus Is Essential in Controlling Wakefulness in Rats. Frontiers in Neuroscience. 15: 645877. PMID 33841086 DOI: 10.3389/fnins.2021.645877  0.491
2021 Wang RF, Guo H, Jiang SY, Liu ZL, Qu WM, Huang ZL, Wang L. Control of wakefulness by lateral hypothalamic glutamatergic neurons in male mice. Journal of Neuroscience Research. PMID 33713502 DOI: 10.1002/jnr.24828  0.388
2021 Yan YD, Chen YQ, Wang CY, Ye CB, Hu ZZ, Behnisch T, Huang ZL, Yang SR. Chronic modafinil therapy ameliorates depressive-like behavior, spatial memory and hippocampal plasticity impairments, and sleep-wake changes in a surgical mouse model of menopause. Translational Psychiatry. 11: 116. PMID 33558464 DOI: 10.1038/s41398-021-01229-6  0.373
2020 Zhao YN, Yan YD, Wang CY, Qu WM, Jhou TC, Huang ZL, Yang SR. The Rostromedial Tegmental Nucleus: Anatomical Studies and Roles in Sleep and Substance Addictions in Rats and Mice. Nature and Science of Sleep. 12: 1215-1223. PMID 33380853 DOI: 10.2147/NSS.S278026  0.472
2020 Li YD, Luo YJ, Xu W, Ge J, Cherasse Y, Wang YQ, Lazarus M, Qu WM, Huang ZL. Ventral pallidal GABAergic neurons control wakefulness associated with motivation through the ventral tegmental pathway. Molecular Psychiatry. PMID 33057171 DOI: 10.1038/s41380-020-00906-0  0.38
2020 Xu W, Wang L, Yuan XS, Wang TX, Li WX, Qu WM, Hong ZY, Huang ZL. Sevoflurane depresses neurons in the medial parabrachial nucleus by potentiating postsynaptic GABA receptors and background potassium channels. Neuropharmacology. 108249. PMID 32931816 DOI: 10.1016/J.Neuropharm.2020.108249  0.335
2020 Yuan MY, Chen ZK, Ni J, Wang TX, Jiang SY, Dong H, Qu WM, Huang ZL, Li RX. Ablation of olfactory bulb glutamatergic neurons induces depressive-like behaviors and sleep disturbances in mice. Psychopharmacology. PMID 32445053 DOI: 10.1007/S00213-020-05552-6  0.392
2020 Liu WY, Liu H, Aggarwal J, Huang ZL, Horner RL. Differential Activating Effects of Thyrotropin-Releasing Hormone and its Analog Taltirelin on Motor Output to the Tongue Musculature In-Vivo. Sleep. PMID 32227104 DOI: 10.1093/Sleep/Zsaa053  0.509
2020 Guo H, Yuan XS, Zhou JC, Chen H, Li SQ, Qu WM, Huang ZL. Whole-Brain Monosynaptic Inputs to Hypoglossal Motor Neurons in Mice. Neuroscience Bulletin. PMID 32096114 DOI: 10.1007/S12264-020-00468-9  0.51
2019 Li R, Wang YQ, Liu WY, Zhang MQ, Li L, Cherasse Y, Schiffmann SN, de Kerchove d'Exaerde A, Lazarus M, Qu WM, Huang ZL. Activation of adenosine A receptors in the olfactory tubercle promotes sleep in rodents. Neuropharmacology. 107923. PMID 31874169 DOI: 10.1016/J.Neuropharm.2019.107923  0.601
2019 Li YD, Ge J, Luo YJ, Xu W, Wang J, Lazarus M, Hong ZY, Qu WM, Huang ZL. High cortical delta power correlates with aggravated allodynia by activating anterior cingulate cortex GABAergic neurons in neuropathic pain mice. Pain. PMID 31651580 DOI: 10.1097/J.Pain.0000000000001725  0.371
2019 Shi HY, Xu W, Guo H, Dong H, Qu WM, Huang ZL. Lesion of intergeniculate leaflet GABAergic neurons attenuates sleep in mice exposed to light. Sleep. PMID 31552427 DOI: 10.1093/Sleep/Zsz212  0.541
2019 Yin D, Dong H, Wang TX, Hu ZZ, Cheng NN, Qu WM, Huang ZL. Glutamate Activates the Histaminergic Tuberomammillary Nucleus and Increases Wakefulness in Rats. Neuroscience. PMID 31202706 DOI: 10.1016/J.Neuroscience.2019.05.032  0.493
2019 Liu YY, Wang TX, Zhou JC, Qu WM, Huang ZL. Dopamine D and D receptors mediate analgesic and hypnotic effects of l-tetrahydropalmatine in a mouse neuropathic pain model. Psychopharmacology. PMID 31172225 DOI: 10.1007/S00213-019-05275-3  0.38
2019 Ma Z, Wang W, Wang T, Xu W, Qu W, Huang Z, Hong Z. Ethanol Induces Sedation and Hypnosis via Inhibiting Histamine Release in Mice. Neurochemical Research. PMID 31093904 DOI: 10.1007/S11064-019-02813-5  0.397
2019 Chen ZK, Yuan XS, Dong H, Wu YF, Chen GH, He M, Qu WM, Huang ZL. Whole-Brain Neural Connectivity to Lateral Pontine Tegmentum GABAergic Neurons in Mice. Frontiers in Neuroscience. 13: 375. PMID 31068780 DOI: 10.3389/Fnins.2019.00375  0.527
2019 Dong H, Wang J, Yang YF, Shen Y, Qu WM, Huang ZL. Dorsal Striatum Dopamine Levels Fluctuate Across the Sleep-Wake Cycle and Respond to Salient Stimuli in Mice. Frontiers in Neuroscience. 13: 242. PMID 30949023 DOI: 10.3389/Fnins.2019.00242  0.55
2019 Zhang F, Zhong R, Li S, Fu Z, Wang R, Wang T, Huang Z, Le W. Alteration in sleep architecture and electroencephalogram as an early sign of Alzheimer's disease preceding the disease pathology and cognitive decline. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 30819626 DOI: 10.1016/J.Jalz.2018.12.004  0.438
2019 Zhang Z, Liu WY, Diao YP, Xu W, Zhong YH, Zhang JY, Lazarus M, Liu YY, Qu WM, Huang ZL. Superior Colliculus GABAergic Neurons Are Essential for Acute Dark Induction of Wakefulness in Mice. Current Biology : Cb. PMID 30713103 DOI: 10.1016/J.Cub.2018.12.031  0.548
2019 Yang Y, Wang T, Guan J, Wang J, Chen J, Liu X, Qian J, Xu X, Qu W, Huang Z, Zhan C. Oral Delivery of Honokiol Microparticles for Nonrapid Eye Movement Sleep. Molecular Pharmaceutics. PMID 30652875 DOI: 10.1021/Acs.Molpharmaceut.8B01016  0.509
2019 Yang Y, Dong H, Huang Z. Midbrain dopaminergic neurons mediate modafinil induced arousal Sleep Medicine. 64. DOI: 10.1016/J.Sleep.2019.11.1208  0.33
2019 Wang T, Wu Y, Xu W, Gong W, Ni J, Qu W, Huang Z. The anxiolytic effects of Bai Le Mian capsule, a traditional Chinese hypnotic in mice Sleep and Biological Rhythms. 17: 191-201. DOI: 10.1007/S41105-018-00199-5  0.317
2018 Yuan XS, Wei HH, Xu W, Wang L, Qu WM, Li RX, Huang ZL. Whole-Brain Monosynaptic Afferent Projections to the Cholecystokinin Neurons of the Suprachiasmatic Nucleus. Frontiers in Neuroscience. 12: 807. PMID 30455627 DOI: 10.3389/Fnins.2018.00807  0.332
2018 Wang TX, Xiong B, Xu W, Wei HH, Qu WM, Hong ZY, Huang ZL. Activation of Parabrachial Nucleus Glutamatergic Neurons Accelerates Reanimation from Sevoflurane Anesthesia in Mice. Anesthesiology. PMID 30325744 DOI: 10.1097/Aln.0000000000002475  0.346
2018 Luo YJ, Li YD, Wang L, Yang SR, Yuan XS, Wang J, Cherasse Y, Lazarus M, Chen JF, Qu WM, Huang ZL. Nucleus accumbens controls wakefulness by a subpopulation of neurons expressing dopamine D receptors. Nature Communications. 9: 1576. PMID 29679009 DOI: 10.1038/S41467-018-03889-3  0.44
2018 Yang SR, Hu ZZ, Luo YJ, Zhao YN, Sun HX, Yin D, Wang CY, Yan YD, Wang DR, Yuan XS, Ye CB, Guo W, Qu WM, Cherasse Y, Lazarus M, ... ... Huang ZL, et al. The rostromedial tegmental nucleus is essential for non-rapid eye movement sleep. Plos Biology. 16: e2002909. PMID 29652889 DOI: 10.1371/Journal.Pbio.2002909  0.599
2017 Zhang Z, Wang HJ, Wang DR, Qu WM, Huang ZL. Red light at intensities above 10 lx alters sleep-wake behavior in mice. Light, Science & Applications. 6: e16231. PMID 30167247 DOI: 10.1038/Lsa.2016.231  0.532
2017 Zhang MQ, Li R, Wang YQ, Huang ZL. Neural Plasticity Is Involved in Physiological Sleep, Depressive Sleep Disturbances, and Antidepressant Treatments. Neural Plasticity. 2017: 5870735. PMID 29181202 DOI: 10.1155/2017/5870735  0.546
2017 Liu J, Zhang MQ, Wu X, Lazarus M, Cherasse Y, Yuan MY, Huang ZL, Li RX. Activation of Parvalbumin Neurons in the Rostro-Dorsal Sector of the Thalamic Reticular Nucleus Promotes Sensitivity to Pain in Mice. Neuroscience. PMID 29042322 DOI: 10.1016/J.Neuroscience.2017.10.013  0.35
2017 Yuan XS, Wang L, Dong H, Qu WM, Yang SR, Cherasse Y, Lazarus M, Schiffmann SN, d'Exaerde AK, Li RX, Huang ZL. Striatal adenosine A2A receptor neurons control active-period sleep via parvalbumin neurons in external globus pallidus. Elife. 6. PMID 29022877 DOI: 10.7554/Elife.29055  0.585
2017 Fang T, Dong H, Xu XH, Yuan XS, Chen ZK, Chen JF, Qu WM, Huang ZL. Adenosine A2A receptor mediates hypnotic effects of ethanol in mice. Scientific Reports. 7: 12678. PMID 28978989 DOI: 10.1038/S41598-017-12689-6  0.504
2017 Oishi Y, Xu Q, Wang L, Zhang BJ, Takahashi K, Takata Y, Luo YJ, Cherasse Y, Schiffmann SN, de Kerchove d'Exaerde A, Urade Y, Qu WM, Huang ZL, Lazarus M. Slow-wave sleep is controlled by a subset of nucleus accumbens core neurons in mice. Nature Communications. 8: 734. PMID 28963505 DOI: 10.1038/S41467-017-00781-4  0.602
2017 Um MY, Kim S, Jin YH, Yoon M, Yang H, Lee J, Jung J, Urade Y, Huang ZL, Kwon S, Cho S. A novel neurological function of rice bran: a standardized rice bran supplement promotes non-rapid eye movement sleep in mice through histamine H1 receptors. Molecular Nutrition & Food Research. PMID 28722302 DOI: 10.1002/Mnfr.201700316  0.576
2017 Lazarus M, Chen JF, Huang ZL, Urade Y, Fredholm BB. Adenosine and Sleep. Handbook of Experimental Pharmacology. PMID 28646346 DOI: 10.1007/164_2017_36  0.584
2017 Wang YQ, Zhang MQ, Li R, Qu WM, Huang ZL. The mutual interaction between sleep and epilepsy on the neurobiological basis and therapy. Current Neuropharmacology. PMID 28486925 DOI: 10.2174/1570159X15666170509101237  0.545
2017 Liu Q, Gan L, Ni J, Chen Y, Chen Y, Huang Z, Huang X, Wen T. Dcf1 Improves Behavior Deficit in Drosophila and Mice Caused by Optogenetic Suppression. Journal of Cellular Biochemistry. PMID 28401598 DOI: 10.1002/Jcb.26048  0.313
2017 Sun HX, Wang DR, Ye CB, Hu ZZ, Wang CY, Huang ZL, Yang SR. Activation of the ventral tegmental area increased wakefulness in mice. Sleep and Biological Rhythms. 15: 107-115. PMID 28386207 DOI: 10.1007/S41105-017-0094-X  0.583
2017 Zhang MQ, Wang TX, Li R, Huang ZL, Han WJ, Dai XC, Wang YQ. Helicid alleviates pain and sleep disturbances in a neuropathic pain-like model in mice. Journal of Sleep Research. PMID 28318068 DOI: 10.1111/Jsr.12518  0.489
2017 Zhang BJ, Huang ZL, Chen JF, Urade Y, Qu WM. Adenosine A2A receptor deficiency attenuates the somnogenic effect of prostaglandin D2 in mice. Acta Pharmacologica Sinica. PMID 28112177 DOI: 10.1038/Aps.2016.140  0.573
2017 Yuan X, Wang L, Dong H, Qu W, Yang S, Cherasse Y, Lazarus M, Schiffmann SN, d'Exaerde AdK, Li R, Huang Z. Author response: Striatal adenosine A2A receptor neurons control active-period sleep via parvalbumin neurons in external globus pallidus Elife. DOI: 10.7554/Elife.29055.030  0.506
2017 Sun H, Wang D, Ye C, Hu Z, Wang C, Huang Z, Yang S. Erratum to: Activation of the ventral tegmental area increased wakefulness in mice Sleep and Biological Rhythms. 15: 343-344. DOI: 10.1007/S41105-017-0115-9  0.357
2016 Zhang BJ, Shao SR, Aritake K, Takeuchi A, Urade Y, Huang ZL, Lazarus M, Qu WM. Interleukin-1β induces sleep independent of prostaglandin D2 in rats and mice. Neuroscience. PMID 27815021 DOI: 10.1016/J.Neuroscience.2016.09.053  0.513
2016 Sun Y, Jiang SY, Ni J, Luo YJ, Chen CR, Hong ZY, Yanagawa Y, Qu WM, Wang L, Huang ZL. Ethanol inhibits histaminergic neurons in mouse tuberomammillary nucleus slices via potentiating GABAergic transmission onto the neurons at both pre- and postsynaptic sites. Acta Pharmacologica Sinica. PMID 27498778 DOI: 10.1038/Aps.2016.66  0.39
2016 Wang YQ, Li R, Wang DR, Cherasse Y, Zhang Z, Zhang MQ, Lavielle O, McEown K, Schiffmann SN, de Kerchove d'Exaerde A, Qu WM, Lazarus M, Huang ZL. Adenosine A2A receptors in the olfactory bulb suppress rapid eye movement sleep in rodents. Brain Structure & Function. PMID 27485749 DOI: 10.1007/S00429-016-1281-2  0.597
2016 Liu ZL, Wu X, Luo YJ, Wang L, Qu WM, Li SQ, Huang ZL. Signaling mechanism underlying the histamine-modulated action of hypoglossal motoneurons. Journal of Neurochemistry. PMID 26811198 DOI: 10.1111/Jnc.13548  0.435
2016 Chen L, Yin D, Wang TX, Guo W, Dong H, Xu Q, Luo YJ, Cherasse Y, Lazarus M, Qiu ZL, Lu J, Qu WM, Huang ZL. Basal Forebrain Cholinergic Neurons Primarily Contribute to Inhibition of Electroencephalogram Delta Activity, Rather than Inducing Behavioral Wakefulness in Mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 26797244 DOI: 10.1038/Npp.2016.13  0.436
2015 Lazarus M, Huang ZL, Urade Y. Osamu Hayaishi-from the discovery of oxygenases in soil microorganisms to unraveling the enigma of sleep in mammals. Temperature (Austin, Tex.). 2: 303-7. PMID 27227031 DOI: 10.1080/23328940.2015.1072658  0.376
2015 Yin D, Liu YY, Wang TX, Hu ZZ, Qu WM, Chen JF, Cheng NN, Huang ZL. Paeoniflorin exerts analgesic and hypnotic effects via adenosine A1 receptors in a mouse neuropathic pain model. Psychopharmacology. PMID 26514553 DOI: 10.1007/S00213-015-4108-6  0.419
2015 Chen C, Sun Y, Luo YJ, Zhao X, Chen JF, Yanagawa Y, Qu W, Huang ZL. Paeoniflorin Promotes Non-rapid Eye Movement Sleep via Adenosine A1 Receptors. The Journal of Pharmacology and Experimental Therapeutics. PMID 26491061 DOI: 10.1124/Jpet.115.227819  0.64
2015 Wang YQ, Li R, Zhang MQ, Zhang Z, Qu WM, Huang ZL. The Neurobiological Mechanisms and Treatments of REM Sleep Disturbances in Depression. Current Neuropharmacology. 13: 543-53. PMID 26412074 DOI: 10.2174/1570159X13666150310002540  0.534
2015 Wu YE, Li YD, Luo YJ, Wang TX, Wang HJ, Chen SN, Qu WM, Huang ZL. Gelsemine alleviates both neuropathic pain and sleep disturbance in partial sciatic nerve ligation mice. Acta Pharmacologica Sinica. PMID 26388157 DOI: 10.1038/Aps.2015.86  0.547
2015 Wang TX, Yin D, Guo W, Liu YY, Li YD, Qu WM, Han WJ, Hong ZY, Huang ZL. Antinociceptive and hypnotic activities of pregabalin in a neuropathic pain-like model in mice. Pharmacology, Biochemistry, and Behavior. 135: 31-9. PMID 25989046 DOI: 10.1016/J.Pbb.2015.05.007  0.5
2015 Wang YQ, Takata Y, Li R, Zhang Z, Zhang MQ, Urade Y, Qu WM, Huang ZL. Doxepin and diphenhydramine increased non-rapid eye movement sleep through blockade of histamine H1 receptors. Pharmacology, Biochemistry, and Behavior. 129: 56-64. PMID 25498564 DOI: 10.1016/J.Pbb.2014.12.002  0.478
2014 Guo JH, Qu WM, Chen SG, Chen XP, Lv K, Huang ZL, Wu YL. Keeping the right time in space: importance of circadian clock and sleep for physiology and performance of astronauts. Military Medical Research. 1: 23. PMID 26000169 DOI: 10.1186/2054-9369-1-23  0.412
2014 Huang ZL, Zhang Z, Qu WM. Roles of adenosine and its receptors in sleep-wake regulation. International Review of Neurobiology. 119: 349-71. PMID 25175972 DOI: 10.1016/B978-0-12-801022-8.00014-3  0.591
2014 Qiu MH, Chen MC, Huang ZL, Lu J. Neuronal activity (c-Fos) delineating interactions of the cerebral cortex and basal ganglia. Frontiers in Neuroanatomy. 8: 13. PMID 24723855 DOI: 10.3389/Fnana.2014.00013  0.37
2014 Liu YY, Yin D, Chen L, Qu WM, Chen CR, Laudon M, Cheng NN, Urade Y, Huang ZL. Piromelatine exerts antinociceptive effect via melatonin, opioid, and 5HT1A receptors and hypnotic effect via melatonin receptors in a mouse model of neuropathic pain. Psychopharmacology. 231: 3973-85. PMID 24700387 DOI: 10.1007/S00213-014-3530-5  0.44
2014 Han Y, Shi YF, Xi W, Zhou R, Tan ZB, Wang H, Li XM, Chen Z, Feng G, Luo M, Huang ZL, Duan S, Yu YQ. Selective activation of cholinergic basal forebrain neurons induces immediate sleep-wake transitions. Current Biology : Cb. 24: 693-8. PMID 24613308 DOI: 10.1016/J.Cub.2014.02.011  0.57
2014 Cho S, Yoon M, Pae AN, Jin YH, Cho NC, Takata Y, Urade Y, Kim S, Kim JS, Yang H, Kim J, Kim J, Han JK, Shimizu M, Huang ZL. Marine polyphenol phlorotannins promote non-rapid eye movement sleep in mice via the benzodiazepine site of the GABAA receptor. Psychopharmacology. 231: 2825-37. PMID 24488362 DOI: 10.1007/S00213-014-3445-1  0.431
2014 Kaushik MK, Aritake K, Kamauchi S, Hayaishi O, Huang ZL, Lazarus M, Urade Y. Prostaglandin D(2) is crucial for seizure suppression and postictal sleep. Experimental Neurology. 253: 82-90. PMID 24333565 DOI: 10.1016/J.Expneurol.2013.12.002  0.427
2014 Xu Q, Xu XH, Qu WM, Lazarus M, Urade Y, Huang ZL. A mouse model mimicking human first night effect for the evaluation of hypnotics. Pharmacology, Biochemistry, and Behavior. 116: 129-36. PMID 24316349 DOI: 10.1016/J.Pbb.2013.11.029  0.582
2014 Xu X, Qiu M, Dong H, Qu W, Urade Y, Huang Z. GABA transporter-1 inhibitor NO-711 alters the EEG power spectra and enhances non-rapid eye movement sleep during the active phase in mice. European Neuropsychopharmacology. 24: 585-594. PMID 24080505 DOI: 10.1016/J.Euroneuro.2013.09.002  0.591
2013 Zhang JP, Xu Q, Yuan XS, Cherasse Y, Schiffmann SN, de Kerchove d'Exaerde A, Qu WM, Urade Y, Lazarus M, Huang ZL, Li RX. Projections of nucleus accumbens adenosine A2A receptor neurons in the mouse brain and their implications in mediating sleep-wake regulation. Frontiers in Neuroanatomy. 7: 43. PMID 24409122 DOI: 10.3389/Fnana.2013.00043  0.465
2013 Xu X, Qu W, Bian M, Huang F, Fei J, Urade Y, Huang Z. Essential roles of GABA transporter-1 in controlling rapid eye movement sleep and in increased slow wave activity after sleep deprivation. Plos One. 8. PMID 24155871 DOI: 10.1371/Journal.Pone.0075823  0.593
2013 Chen CR, Yang SR, Liu YY, Qu WM, Urade Y, Huang ZL. Roles of adrenergic α1 and dopamine D1 and D2 receptors in the mediation of the desynchronization effects of modafinil in a mouse EEG synchronization model. Plos One. 8: e76102. PMID 24116090 DOI: 10.1371/Journal.Pone.0076102  0.348
2013 Chen MC, Yu H, Huang ZL, Lu J. Rapid eye movement sleep behavior disorder. Current Opinion in Neurobiology. 23: 793-8. PMID 23518139 DOI: 10.1016/J.Conb.2013.02.019  0.504
2013 Lazarus M, Chen JF, Urade Y, Huang ZL. Role of the basal ganglia in the control of sleep and wakefulness. Current Opinion in Neurobiology. 23: 780-5. PMID 23465424 DOI: 10.1016/J.Conb.2013.02.001  0.557
2013 Wang Q, Yue X, Qu W, Tan R, Zheng P, Urade Y, Huang Z. Morphine Inhibits Sleep-Promoting Neurons in the Ventrolateral Preoptic Area Via Mu Receptors and Induces Wakefulness in Rats Neuropsychopharmacology. 38: 791-801. PMID 23303062 DOI: 10.1038/Npp.2012.244  0.554
2012 Qiu MH, Liu W, Qu WM, Urade Y, Lu J, Huang ZL. The role of nucleus accumbens core/shell in sleep-wake regulation and their involvement in modafinil-induced arousal. Plos One. 7: e45471. PMID 23029032 DOI: 10.1371/Journal.Pone.0045471  0.492
2012 Lazarus M, Huang ZL, Lu J, Urade Y, Chen JF. How do the basal ganglia regulate sleep-wake behavior? Trends in Neurosciences. 35: 723-32. PMID 22858523 DOI: 10.1016/J.Tins.2012.07.001  0.542
2012 Wei B, Huang Z, He S, Sun C, You Y, Liu F, Yang Z. The onion skin-like organization of the septum arises from multiple embryonic origins to form multiple adult neuronal fates. Neuroscience. 222: 110-23. PMID 22820053 DOI: 10.1016/J.Neuroscience.2012.07.016  0.307
2012 Chen C, Zhou X, Luo Y, Huang Z, Urade Y, Qu W. Magnolol, a major bioactive constituent of the bark of Magnolia officinalis, induces sleep via the benzodiazepine site of GABAA receptor in mice Neuropharmacology. 63: 1191-1199. PMID 22771461 DOI: 10.1016/J.Neuropharm.2012.06.031  0.609
2012 Yang SR, Sun H, Huang ZL, Yao MH, Qu WM. Repeated sleep restriction in adolescent rats altered sleep patterns and impaired spatial learning/memory ability. Sleep. 35: 849-59. PMID 22654204 DOI: 10.5665/sleep.1888  0.394
2012 Liu Z, Xu X, Liu T, Hong Z, Urade Y, Huang Z, Qu W. Safranal Enhances Non-Rapid Eye Movement Sleep in Pentobarbital-Treated Mice Cns Neuroscience & Therapeutics. 18: 623-630. PMID 22632633 DOI: 10.1111/J.1755-5949.2012.00334.X  0.611
2012 Qu WM, Yue XF, Sun Y, Fan K, Chen CR, Hou YP, Urade Y, Huang ZL. Honokiol promotes non-rapid eye movement sleep via the benzodiazepine site of the GABA(A) receptor in mice. British Journal of Pharmacology. 167: 587-98. PMID 22537192 DOI: 10.1111/J.1476-5381.2012.02010.X  0.564
2012 Li YY, Hu ZZ, Huang ZL, Yang SR. [Role of stress in depression insomnia and sleep characteristics of commonly used animal stress models]. Yao Xue Xue Bao = Acta Pharmaceutica Sinica. 47: 1-6. PMID 22493798  0.312
2012 Masaki M, Aritake K, Tanaka H, Shoyama Y, Huang Z, Urade Y. Crocin promotes non‐rapid eye movement sleep in mice Molecular Nutrition & Food Research. 56: 304-308. PMID 22038919 DOI: 10.1002/Mnfr.201100181  0.581
2012 Wang Y, Tu Z, Xu X, Li R, Qu W, Urade Y, Huang Z. Acute administration of fluoxetine normalizes rapid eye movement sleep abnormality, but not depressive behaviors in olfactory bulbectomized rats. Journal of Neurochemistry. 120: 314-324. PMID 22035172 DOI: 10.1111/J.1471-4159.2011.07558.X  0.516
2012 Liu TY, Hong ZY, Qu WM, Huang ZL. [Advances in the study of histaminergic systems and sleep-wake regulation]. Yao Xue Xue Bao = Acta Pharmaceutica Sinica. 46: 247-52. PMID 21626776  0.491
2012 Liu X, Zhang B, Xu X, Huang Z, Qu W. Lesions of suprachiasmatic nucleus modify sleep structure but do not alter the total amount of daily sleep in rats Sleep and Biological Rhythms. 10: 293-301. DOI: 10.1111/J.1479-8425.2012.00572.X  0.552
2012 Huo X, Liu W, Qiu M, Huang Z, Qu W. Genistein induces non-rapid eye movement sleep in mice Sleep and Biological Rhythms. 10: 278-286. DOI: 10.1111/J.1479-8425.2012.00571.X  0.609
2012 Omori K, Kagami Y, Yokoyama C, Moriyama T, Matsumoto N, Masaki M, Nakamura H, Kamasaka H, Shiraishi K, Kometani T, Kuriki T, Huang Z, Urade Y. Promotion of non–rapid eye movement sleep in mice after oral administration of ornithine Sleep and Biological Rhythms. 10: 38-45. DOI: 10.1111/J.1479-8425.2011.00515.X  0.586
2011 Lazarus M, Shen HY, Cherasse Y, Qu WM, Huang ZL, Bass CE, Winsky-Sommerer R, Semba K, Fredholm BB, Boison D, Hayaishi O, Urade Y, Chen JF. Arousal effect of caffeine depends on adenosine A2A receptors in the shell of the nucleus accumbens. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 10067-75. PMID 21734299 DOI: 10.1523/Jneurosci.6730-10.2011  0.325
2011 Huang ZL, Urade Y, Hayaishi O. The role of adenosine in the regulation of sleep. Current Topics in Medicinal Chemistry. 11: 1047-57. PMID 21401496 DOI: 10.2174/156802611795347654  0.578
2011 YAN M, XU X, HUANG Z, YAO M, URADE Y, QU W. Selection of optimal epoch duration in assessment of rodent sleep-wake profiles Sleep and Biological Rhythms. 9: 46-55. DOI: 10.1111/J.1479-8425.2010.00484.X  0.541
2011 Huang ZL, Urade Y, Hayaishi O. Key roles of the histaminergic system in sleep-wake regulation Sleep and Biological Rhythms. 9: 34-37. DOI: 10.1111/J.1479-8425.2010.00471.X  0.606
2010 Qu W, Xu X, Yan M, Wang Y, Urade Y, Huang Z. Essential Role of Dopamine D2 Receptor in the Maintenance of Wakefulness, But Not in Homeostatic Regulation of Sleep, in Mice The Journal of Neuroscience. 30: 4382-4389. PMID 20335474 DOI: 10.1523/Jneurosci.4936-09.2010  0.546
2010 Nagata N, Kashiwagi K, Yamamoto T, Okazaki I, Mitamura E, Qu W, Michael L, Huang Z, Fujimori K, Urade Y. Function of a novel SOX5 splicing isoform expressed in mouse brain during sleep Neuroscience Research. 68. DOI: 10.1016/J.Neures.2010.07.2347  0.501
2009 Qiu MH, Qu WM, Xu XH, Yan MM, Urade Y, Huang ZL. D(1)/D(2) receptor-targeting L-stepholidine, an active ingredient of the Chinese herb Stephonia, induces non-rapid eye movement sleep in mice. Pharmacology, Biochemistry, and Behavior. 94: 16-23. PMID 19604496 DOI: 10.1016/J.Pbb.2009.06.018  0.605
2009 Makino Y, Kondo S, Nishimura Y, Tsukamoto Y, Huang Z, Urade Y. Hastatoside and verbenalin are sleep‐promoting components in Verbena officinalis Sleep and Biological Rhythms. 7: 211-217. DOI: 10.1111/J.1479-8425.2009.00405.X  0.547
2008 Oishi Y, Huang ZL, Fredholm BB, Urade Y, Hayaishi O. Adenosine in the tuberomammillary nucleus inhibits the histaminergic system via A1 receptors and promotes non-rapid eye movement sleep. Proceedings of the National Academy of Sciences of the United States of America. 105: 19992-7. PMID 19066225 DOI: 10.1073/Pnas.0810926105  0.597
2008 Qu W, Huang Z, Matsumoto N, Xu X, Urade Y. Drug delivery through a chronically implanted stomach catheter improves efficiency of evaluating wake-promoting components. Journal of Neuroscience Methods. 175: 58-63. PMID 18761374 DOI: 10.1016/J.Jneumeth.2008.08.002  0.379
2008 Qu W, Huang Z, Xu X, Matsumoto N, Urade Y. Dopaminergic D1 and D2 Receptors Are Essential for the Arousal Effect of Modafinil The Journal of Neuroscience. 28: 8462-8469. PMID 18716204 DOI: 10.1523/Jneurosci.1819-08.2008  0.303
2008 Terao A, Huang ZL, Wisor JP, Mochizuki T, Gerashchenko D, Urade Y, Kilduff TS. Gene expression in the rat brain during prostaglandin D2 and adenosinergically-induced sleep. Journal of Neurochemistry. 105: 1480-98. PMID 18331290 DOI: 10.1111/J.1471-4159.2008.05257.X  0.535
2008 Kohtoh S, Taguchi Y, Matsumoto N, Wada M, Huang Z, Urade Y. Algorithm for sleep scoring in experimental animals based on fast Fourier transform power spectrum analysis of the electroencephalogram Sleep and Biological Rhythms. 6: 163-171. DOI: 10.1111/J.1479-8425.2008.00355.X  0.512
2007 Nishida N, Huang Z, Mikuni N, Miura Y, Urade Y, Hashimoto N. Deep brain stimulation of the posterior hypothalamus activates the histaminergic system to exert antiepileptic effect in rat pentylenetetrazol model Experimental Neurology. 205: 132-144. PMID 17321522 DOI: 10.1016/J.Expneurol.2007.01.021  0.304
2007 Huang ZL, Urade Y, Hayaishi O. Prostaglandins and adenosine in the regulation of sleep and wakefulness. Current Opinion in Pharmacology. 7: 33-8. PMID 17129762 DOI: 10.1016/J.Coph.2006.09.004  0.611
2006 Qu WM, Huang ZL, Xu XH, Aritake K, Eguchi N, Nambu F, Narumiya S, Urade Y, Hayaishi O. Lipocalin-type prostaglandin D synthase produces prostaglandin D2 involved in regulation of physiological sleep. Proceedings of the National Academy of Sciences of the United States of America. 103: 17949-54. PMID 17093043 DOI: 10.1073/pnas.0608581103  0.521
2006 Yoshida G, Li MX, Horiuchi M, Nakagawa S, Sakata M, Kuchiiwa S, Kuchiiwa T, Jalil MA, Begum L, Lu YB, Iijima M, Hanada T, Nakazato M, Huang ZL, Eguchi N, et al. Fasting-induced reduction in locomotor activity and reduced response of orexin neurons in carnitine-deficient mice. Neuroscience Research. 55: 78-86. PMID 16540195 DOI: 10.1016/J.Neures.2006.02.003  0.381
2006 Huang ZL, Mochizuki T, Qu WM, Hong ZY, Watanabe T, Urade Y, Hayaishi O. Altered sleep-wake characteristics and lack of arousal response to H3 receptor antagonist in histamine H1 receptor knockout mice. Proceedings of the National Academy of Sciences of the United States of America. 103: 4687-92. PMID 16537376 DOI: 10.1073/Pnas.0600451103  0.518
2005 Huang ZL, Qu WM, Eguchi N, Chen JF, Schwarzschild MA, Fredholm BB, Urade Y, Hayaishi O. Adenosine A2A, but not A1, receptors mediate the arousal effect of caffeine. Nature Neuroscience. 8: 858-9. PMID 15965471 DOI: 10.1038/Nn1491  0.35
2005 Hong ZY, Huang ZL, Qu WM, Eguchi N, Urade Y, Hayaishi O. An adenosine A receptor agonist induces sleep by increasing GABA release in the tuberomammillary nucleus to inhibit histaminergic systems in rats. Journal of Neurochemistry. 92: 1542-9. PMID 15748171 DOI: 10.1111/J.1471-4159.2004.02991.X  0.516
2005 Hong Z, Huang Z, Qu W, Eguchi N. Orexin A promotes histamine, but not norepinephrine or serotonin, release in frontal cortex of mice. Acta Pharmacologica Sinica. 26: 155-159. PMID 15663891 DOI: 10.1111/J.1745-7254.2005.00523.X  0.301
2004 Chu M, Huang ZL, Qu WM, Eguchi N, Yao MH, Urade Y. Extracellular histamine level in the frontal cortex is positively correlated with the amount of wakefulness in rats. Neuroscience Research. 49: 417-20. PMID 15236867 DOI: 10.1016/J.Neures.2004.05.001  0.426
2004 Hayaishi O, Huang ZL. Role of orexin and prostaglandin E(2) in activating histaminergic neurotransmission. Drug News & Perspectives. 17: 105-9. PMID 15098064 DOI: 10.1358/Dnp.2004.17.2.829043  0.512
2004 Sakata M, Eguchi N, Qu WM, Huang ZL, Chen JF, Schwarzschild MA, Urade Y, Hayaishi O. Lack of rebound of non-rapid eye movement sleep after sleep deprivation in adenosine A2A receptor knockout mice Sleep and Biological Rhythms. 2: S56. DOI: 10.1111/J.1479-8425.2004.00115.X  0.577
2003 Urade Y, Eguchi N, Qu WM, Sakata M, Huang ZL, Chen JF, Schwarzschild MA, Fink JS, Hayaishi O. Sleep regulation in adenosine A2A receptor-deficient mice. Neurology. 61: S94-6. PMID 14663019 DOI: 10.1212/01.Wnl.0000095222.41066.5E  0.576
2003 Huang ZL, Sato Y, Mochizuki T, Okada T, Qu WM, Yamatodani A, Urade Y, Hayaishi O. Prostaglandin E2 activates the histaminergic system via the EP4 receptor to induce wakefulness in rats. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 5975-83. PMID 12853415 DOI: 10.1523/Jneurosci.23-14-05975.2003  0.375
2001 Mizoguchi A, Eguchi N, Kimura K, Kiyohara Y, Qu WM, Huang ZL, Mochizuki T, Lazarus M, Kobayashi T, Kaneko T, Narumiya S, Urade Y, Hayaishi O. Dominant localization of prostaglandin D receptors on arachnoid trabecular cells in mouse basal forebrain and their involvement in the regulation of non-rapid eye movement sleep. Proceedings of the National Academy of Sciences of the United States of America. 98: 11674-9. PMID 11562489 DOI: 10.1073/Pnas.201398898  0.538
2001 Huang ZL, Qu WM, Li WD, Mochizuki T, Eguchi N, Watanabe T, Urade Y, Hayaishi O. Arousal effect of orexin A depends on activation of the histaminergic system. Proceedings of the National Academy of Sciences of the United States of America. 98: 9965-70. PMID 11493714 DOI: 10.1073/Pnas.181330998  0.592
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