| Year |
Citation |
Score |
| 2023 |
Illes P, Ulrich H, Chen JF, Tang Y. Purinergic receptors in cognitive disturbances. Neurobiology of Disease. 106229. PMID 37453562 DOI: 10.1016/j.nbd.2023.106229 |
0.305 |
|
| 2022 |
Shen HY, Baer SB, Gesese R, Cook JM, Weltha L, Coffman SQ, Wu J, Chen JF, Gao M, Ji T. Adenosine-A Receptor Signaling Plays a Crucial Role in Sudden Unexpected Death in Epilepsy. Frontiers in Pharmacology. 13: 910535. PMID 35754505 DOI: 10.3389/fphar.2022.910535 |
0.304 |
|
| 2020 |
Zeng XJ, Li P, Ning YL, Zhao Y, Peng Y, Yang N, Xu YW, Chen JF, Zhou YG. A R inhibition in alleviating spatial recognition memory impairment after TBI is associated with improvement in autophagic flux in RSC. Journal of Cellular and Molecular Medicine. PMID 32394486 DOI: 10.1111/Jcmm.15361 |
0.352 |
|
| 2019 |
Chen Y, Zhang ZX, Zheng LP, Wang L, Liu YF, Yin WY, Chen YY, Wang XS, Hou ST, Chen JF, Zheng RY. The adenosine A receptor antagonist SCH58261 reduces macrophage/microglia activation and protects against experimental autoimmune encephalomyelitis in mice. Neurochemistry International. 104490. PMID 31226280 DOI: 10.1016/J.Neuint.2019.104490 |
0.396 |
|
| 2019 |
Korkutata M, Saitoh T, Cherasse Y, Ioka S, Duo F, Qin R, Murakoshi N, Fujii S, Zhou X, Sugiyama F, Chen JF, Kumagai H, Nagase H, Lazarus M. Corrigendum to "Enhancing endogenous adenosine A receptor signaling induces slow-wave sleep without affecting body temperature and cardiovascular function" [Neuropharmacology 144 (2019) 122-132]. Neuropharmacology. PMID 31101360 DOI: 10.1016/J.Neuropharm.2019.04.027 |
0.334 |
|
| 2019 |
Hong S, Kang S, Chen J, Choi D. Activation of Adenosine A2A receptor-containing indirect medium spiny neurons in the dorsomedial striatum reduces ethanol containing conditioned reward seeking Ibro Reports. 6: S492. DOI: 10.1016/J.Ibror.2019.07.1543 |
0.349 |
|
| 2018 |
Korkutata M, Saitoh T, Cherasse Y, Ioka S, Duo F, Qin R, Murakoshi N, Fujii S, Zhou X, Sugiyama F, Chen JF, Kumagai H, Nagase H, Lazarus M. Enhancing endogenous adenosine A receptor signaling induces slow-wave sleep without affecting body temperature and cardiovascular function. Neuropharmacology. PMID 30336152 DOI: 10.1016/J.Neuropharm.2018.10.022 |
0.377 |
|
| 2018 |
Li Y, Pan X, He Y, Ruan Y, Huang L, Zhou Y, Hou Z, He C, Wang Z, Zhang X, Chen JF. Pharmacological Blockade of Adenosine A but Not A Receptors Enhances Goal-Directed Valuation in Satiety-Based Instrumental Behavior. Frontiers in Pharmacology. 9: 393. PMID 29740319 DOI: 10.3389/Fphar.2018.00393 |
0.369 |
|
| 2018 |
Zheng W, Zhou J, Luan Y, Yang J, Ge Y, Wang M, Wu B, Wu Z, Chen X, Li F, Li Z, Vakal S, Guo W, Chen JF. Spatiotemporal Control of GPR37 Signaling and Its Behavioral Effects by Optogenetics. Frontiers in Molecular Neuroscience. 11: 95. PMID 29643766 DOI: 10.3389/Fnmol.2018.00095 |
0.342 |
|
| 2018 |
Zeng XJ, Li P, Ning YL, Zhao Y, Peng Y, Yang N, Zhao ZA, Chen JF, Zhou YG. Impaired autophagic flux is associated with the severity of trauma and the role of AR in brain cells after traumatic brain injury. Cell Death & Disease. 9: 252. PMID 29449536 DOI: 10.1038/S41419-018-0316-4 |
0.326 |
|
| 2017 |
Fang T, Dong H, Xu XH, Yuan XS, Chen ZK, Chen JF, Qu WM, Huang ZL. Adenosine A2A receptor mediates hypnotic effects of ethanol in mice. Scientific Reports. 7: 12678. PMID 28978989 DOI: 10.1038/S41598-017-12689-6 |
0.324 |
|
| 2017 |
Li Z, Chen X, Wang T, Gao Y, Li F, Chen L, Xue J, He Y, Li Y, Guo W, Zheng W, Zhang L, Ye F, Ren X, Feng Y, ... ... Chen JF, et al. The Corticostriatal Adenosine A2A Receptor Controls Maintenance and Retrieval of Spatial Working Memory. Biological Psychiatry. PMID 28941549 DOI: 10.1016/J.Biopsych.2017.07.017 |
0.338 |
|
| 2017 |
Lazarus M, Chen JF, Huang ZL, Urade Y, Fredholm BB. Adenosine and Sleep. Handbook of Experimental Pharmacology. PMID 28646346 DOI: 10.1007/164_2017_36 |
0.37 |
|
| 2017 |
Zhao ZA, Li P, Ye SY, Ning YL, Wang H, Peng Y, Yang N, Zhao Y, Zhang ZH, Chen JF, Zhou YG. Perivascular AQP4 dysregulation in the hippocampal CA1 area after traumatic brain injury is alleviated by adenosine A2A receptor inactivation. Scientific Reports. 7: 2254. PMID 28533515 DOI: 10.1038/S41598-017-02505-6 |
0.334 |
|
| 2017 |
Dai QX, Geng WJ, Zhuang XX, Wang HF, Mo YC, Xin H, Chen JF, Wang JL. Electroacupuncture-induced neuroprotection against focal cerebral ischemia in the rat is mediated by adenosine A1 receptors. Neural Regeneration Research. 12: 228-234. PMID 28400804 DOI: 10.4103/1673-5374.200806 |
0.347 |
|
| 2017 |
Zhao ZA, Ning YL, Li P, Yang N, Peng Y, Xiong RP, Zhao Y, Liu D, Zeng XJ, Chen JF, Zhou YG. Widespread hyperphosphorylated tau in the working memory circuit early after cortical impact injury of brain (Original study). Behavioural Brain Research. PMID 28163095 DOI: 10.1016/J.Bbr.2017.02.002 |
0.303 |
|
| 2017 |
Zhang BJ, Huang ZL, Chen JF, Urade Y, Qu WM. Adenosine A2A receptor deficiency attenuates the somnogenic effect of prostaglandin D2 in mice. Acta Pharmacologica Sinica. PMID 28112177 DOI: 10.1038/Aps.2016.140 |
0.356 |
|
| 2016 |
Hu Q, Ren X, Liu Y, Li Z, Zhang L, Chen X, He C, Chen JF. Aberrant adenosine A2A receptor signaling contributes to neurodegeneration and cognitive impairments in a mouse model of synucleinopathy. Experimental Neurology. PMID 27342081 DOI: 10.1016/J.Expneurol.2016.05.040 |
0.326 |
|
| 2015 |
Zhang S, Li H, Li B, Zhong D, Gu X, Tang L, Wang Y, Wang C, Zhou R, Li Y, He Y, Chen M, Huo Y, Liu XL, Chen JF. Adenosine A1 Receptors Selectively Modulate Oxygen-Induced Retinopathy at the Hyperoxic and Hypoxic Phases by Distinct Cellular Mechanisms. Investigative Ophthalmology & Visual Science. 56: 8108-8119. PMID 26720463 DOI: 10.1167/iovs.15-17202 |
0.36 |
|
| 2015 |
Shang P, He ZY, Chen JF, Huang SY, Liu BH, Liu HX, Wang XT. Absence of the Adenosine A2A Receptor Confers Pulmonary Arterial Hypertension Through RhoA/ROCK Signaling Pathway in Mice. Journal of Cardiovascular Pharmacology. 66: 569-75. PMID 26647014 DOI: 10.1097/Fjc.0000000000000305 |
0.337 |
|
| 2015 |
Yin D, Liu YY, Wang TX, Hu ZZ, Qu WM, Chen JF, Cheng NN, Huang ZL. Paeoniflorin exerts analgesic and hypnotic effects via adenosine A1 receptors in a mouse neuropathic pain model. Psychopharmacology. PMID 26514553 DOI: 10.1007/S00213-015-4108-6 |
0.341 |
|
| 2015 |
Chen C, Sun Y, Luo YJ, Zhao X, Chen JF, Yanagawa Y, Qu W, Huang ZL. Paeoniflorin Promotes Non-rapid Eye Movement Sleep via Adenosine A1 Receptors. The Journal of Pharmacology and Experimental Therapeutics. PMID 26491061 DOI: 10.1124/Jpet.115.227819 |
0.42 |
|
| 2015 |
Li Y, He Y, Chen M, Pu Z, Chen L, Li P, Li B, Li H, Huang Z, Li Z, Chen JF. Opotogenetic Activation of Adenosine A2A Receptor Signaling in the Dorsomedial Striatopallidal Neurons Suppresses Goal-Directed Behavior. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 26216520 DOI: 10.1038/Npp.2015.227 |
0.337 |
|
| 2015 |
Li W, Silva HB, Real J, Wang YM, Rial D, Li P, Payen MP, Zhou Y, Muller CE, Tomé AR, Cunha RA, Chen JF. Inactivation of adenosine A2A receptors reverses working memory deficits at early stages of Huntington's disease models. Neurobiology of Disease. 79: 70-80. PMID 25892655 DOI: 10.1016/J.Nbd.2015.03.030 |
0.445 |
|
| 2015 |
Matos M, Shen HY, Augusto E, Wang Y, Wei CJ, Wang YT, Agostinho P, Boison D, Cunha RA, Chen JF. Deletion of Adenosine A2A Receptors from Astrocytes Disrupts Glutamate Homeostasis Leading to Psychomotor and Cognitive Impairment: Relevance to Schizophrenia. Biological Psychiatry. PMID 25869810 DOI: 10.1016/J.Biopsych.2015.02.026 |
0.738 |
|
| 2015 |
Yan T, Xiong W, Huang F, Zheng F, Ying H, Chen JF, Qu J, Zhou X. Daily Injection But Not Continuous Infusion of Apomorphine Inhibits Form-Deprivation Myopia in Mice. Investigative Ophthalmology & Visual Science. 56: 2475-85. PMID 25744977 DOI: 10.1167/Iovs.13-12361 |
0.347 |
|
| 2015 |
Bai G, Cheung I, Shulha HP, Coelho JE, Li P, Dong X, Jakovcevski M, Wang Y, Grigorenko A, Jiang Y, Hoss A, Patel K, Zheng M, Rogaev E, Myers RH, ... ... Chen JF, et al. Epigenetic dysregulation of hairy and enhancer of split 4 (HES4) is associated with striatal degeneration in postmortem Huntington brains. Human Molecular Genetics. 24: 1441-56. PMID 25480889 DOI: 10.1093/Hmg/Ddu561 |
0.304 |
|
| 2014 |
Chen JF. Adenosine receptor control of cognition in normal and disease. International Review of Neurobiology. 119: 257-307. PMID 25175970 DOI: 10.1016/B978-0-12-801022-8.00012-X |
0.444 |
|
| 2014 |
Chen JF, Lee CF, Chern Y. Adenosine receptor neurobiology: overview. International Review of Neurobiology. 119: 1-49. PMID 25175959 DOI: 10.1016/B978-0-12-801022-8.00001-5 |
0.475 |
|
| 2014 |
Huang F, Yan T, Shi F, An J, Xie R, Zheng F, Li Y, Chen J, Qu J, Zhou X. Activation of dopamine D2 receptor is critical for the development of form-deprivation myopia in the C57BL/6 mouse. Investigative Ophthalmology & Visual Science. 55: 5537-44. PMID 25097246 DOI: 10.1167/Iovs.13-13211 |
0.364 |
|
| 2014 |
Wang T, Xi NN, Chen Y, Shang XF, Hu Q, Chen JF, Zheng RY. Chronic caffeine treatment protects against experimental autoimmune encephalomyelitis in mice: therapeutic window and receptor subtype mechanism. Neuropharmacology. 86: 203-11. PMID 25019206 DOI: 10.1016/J.Neuropharm.2014.06.029 |
0.42 |
|
| 2014 |
Wei CJ, Augusto E, Gomes CA, Singer P, Wang Y, Boison D, Cunha RA, Yee BK, Chen JF. Regulation of fear responses by striatal and extrastriatal adenosine A2A receptors in forebrain. Biological Psychiatry. 75: 855-63. PMID 23820821 DOI: 10.1016/J.Biopsych.2013.05.003 |
0.74 |
|
| 2013 |
Shen HY, Canas PM, Garcia-Sanz P, Lan JQ, Boison D, Moratalla R, Cunha RA, Chen JF. Adenosine Aâ‚‚A receptors in striatal glutamatergic terminals and GABAergic neurons oppositely modulate psychostimulant action and DARPP-32 phosphorylation. Plos One. 8: e80902. PMID 24312250 DOI: 10.1371/Journal.Pone.0080902 |
0.406 |
|
| 2013 |
Matos M, Augusto E, Agostinho P, Cunha RA, Chen JF. Antagonistic interaction between adenosine A2A receptors and Na+/K+-ATPase-α2 controlling glutamate uptake in astrocytes. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 18492-502. PMID 24259572 DOI: 10.1523/Jneurosci.1828-13.2013 |
0.341 |
|
| 2013 |
Ning YL, Yang N, Chen X, Xiong RP, Zhang XZ, Li P, Zhao Y, Chen XY, Liu P, Peng Y, Wang ZG, Chen JF, Zhou YG. Adenosine A2A receptor deficiency alleviates blast-induced cognitive dysfunction. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 33: 1789-98. PMID 23921902 DOI: 10.1038/Jcbfm.2013.127 |
0.388 |
|
| 2013 |
Augusto E, Matos M, Sévigny J, El-Tayeb A, Bynoe MS, Müller CE, Cunha RA, Chen JF. Ecto-5'-nucleotidase (CD73)-mediated formation of adenosine is critical for the striatal adenosine A2A receptor functions. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 11390-9. PMID 23843511 DOI: 10.1523/Jneurosci.5817-12.2013 |
0.363 |
|
| 2013 |
Chen JF, Eltzschig HK, Fredholm BB. Adenosine receptors as drug targets--what are the challenges? Nature Reviews. Drug Discovery. 12: 265-86. PMID 23535933 DOI: 10.1038/Nrd3955 |
0.423 |
|
| 2013 |
Dai SS, Wang H, Yang N, An JH, Li W, Ning YL, Zhu PF, Chen JF, Zhou YG. Plasma glutamate-modulated interaction of A2AR and mGluR5 on BMDCs aggravates traumatic brain injury-induced acute lung injury. The Journal of Experimental Medicine. 210: 839-51. PMID 23478188 DOI: 10.1084/Jem.20122196 |
0.36 |
|
| 2013 |
Lazarus M, Chen JF, Urade Y, Huang ZL. Role of the basal ganglia in the control of sleep and wakefulness. Current Opinion in Neurobiology. 23: 780-5. PMID 23465424 DOI: 10.1016/J.Conb.2013.02.001 |
0.319 |
|
| 2013 |
Wills AM, Eberly S, Tennis M, Lang AE, Messing S, Togasaki D, Tanner CM, Kamp C, Chen JF, Oakes D, McDermott MP, Schwarzschild MA. Caffeine consumption and risk of dyskinesia in CALM-PD. Movement Disorders : Official Journal of the Movement Disorder Society. 28: 380-3. PMID 23339054 DOI: 10.1002/Mds.25319 |
0.371 |
|
| 2013 |
Singer P, Wei CJ, Chen JF, Boison D, Yee BK. Deletion of striatal adenosine A(2A) receptor spares latent inhibition and prepulse inhibition but impairs active avoidance learning. Behavioural Brain Research. 242: 54-61. PMID 23276608 DOI: 10.1016/J.Bbr.2012.12.024 |
0.762 |
|
| 2012 |
Lazarus M, Huang ZL, Lu J, Urade Y, Chen JF. How do the basal ganglia regulate sleep-wake behavior? Trends in Neurosciences. 35: 723-32. PMID 22858523 DOI: 10.1016/J.Tins.2012.07.001 |
0.337 |
|
| 2012 |
Shen HY, Singer P, Lytle N, Wei CJ, Lan JQ, Williams-Karnesky RL, Chen JF, Yee BK, Boison D. Adenosine augmentation ameliorates psychotic and cognitive endophenotypes of schizophrenia. The Journal of Clinical Investigation. 122: 2567-77. PMID 22706302 DOI: 10.1172/Jci62378 |
0.739 |
|
| 2012 |
Yao SQ, Li ZZ, Huang QY, Li F, Wang ZW, Augusto E, He JC, Wang XT, Chen JF, Zheng RY. Genetic inactivation of the adenosine A(2A) receptor exacerbates brain damage in mice with experimental autoimmune encephalomyelitis. Journal of Neurochemistry. 123: 100-12. PMID 22639925 DOI: 10.1111/J.1471-4159.2012.07807.X |
0.526 |
|
| 2012 |
Mills JH, Kim DG, Krenz A, Chen JF, Bynoe MS. A2A adenosine receptor signaling in lymphocytes and the central nervous system regulates inflammation during experimental autoimmune encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). 188: 5713-22. PMID 22529293 DOI: 10.4049/Jimmunol.1200545 |
0.393 |
|
| 2012 |
Matos M, Augusto E, Santos-Rodrigues AD, Schwarzschild MA, Chen JF, Cunha RA, Agostinho P. Adenosine A2A receptors modulate glutamate uptake in cultured astrocytes and gliosomes. Glia. 60: 702-16. PMID 22298379 DOI: 10.1002/Glia.22290 |
0.428 |
|
| 2011 |
Lazarus M, Shen HY, Cherasse Y, Qu WM, Huang ZL, Bass CE, Winsky-Sommerer R, Semba K, Fredholm BB, Boison D, Hayaishi O, Urade Y, Chen JF. Arousal effect of caffeine depends on adenosine A2A receptors in the shell of the nucleus accumbens. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 10067-75. PMID 21734299 DOI: 10.1523/Jneurosci.6730-10.2011 |
0.486 |
|
| 2011 |
Huang NK, Lin JH, Lin JT, Lin CI, Liu EM, Lin CJ, Chen WP, Shen YC, Chen HM, Chen JB, Lai HL, Yang CW, Chiang MC, Wu YS, Chang C, ... Chen JF, et al. A new drug design targeting the adenosinergic system for Huntington's disease. Plos One. 6: e20934. PMID 21713039 DOI: 10.1371/Journal.Pone.0020934 |
0.42 |
|
| 2011 |
Wei CJ, Singer P, Coelho J, Boison D, Feldon J, Yee BK, Chen JF. Selective inactivation of adenosine A(2A) receptors in striatal neurons enhances working memory and reversal learning. Learning & Memory (Cold Spring Harbor, N.Y.). 18: 459-74. PMID 21693634 DOI: 10.1101/Lm.2136011 |
0.745 |
|
| 2011 |
Garcia GE, Truong LD, Chen JF, Johnson RJ, Feng L. Adenosine A(2A) receptor activation prevents progressive kidney fibrosis in a model of immune-associated chronic inflammation. Kidney International. 80: 378-88. PMID 21508927 DOI: 10.1038/ki.2011.101 |
0.325 |
|
| 2011 |
Wei CJ, Li W, Chen JF. Normal and abnormal functions of adenosine receptors in the central nervous system revealed by genetic knockout studies. Biochimica Et Biophysica Acta. 1808: 1358-79. PMID 21185258 DOI: 10.1016/J.Bbamem.2010.12.018 |
0.764 |
|
| 2011 |
Chen JF, Chern Y. Impacts of methylxanthines and adenosine receptors on neurodegeneration: Human and experimental studies Handbook of Experimental Pharmacology. 200: 267-310. PMID 20859800 DOI: 10.1007/978-3-642-13443-2_10 |
0.453 |
|
| 2011 |
Xiao D, Cassin JJ, Healy B, Burdett TC, Chen JF, Fredholm BB, Schwarzschild MA. Deletion of adenosine Aâ‚ or A(â‚‚A) receptors reduces L-3,4-dihydroxyphenylalanine-induced dyskinesia in a model of Parkinson's disease. Brain Research. 1367: 310-8. PMID 20828543 DOI: 10.1016/J.Brainres.2010.08.099 |
0.451 |
|
| 2010 |
Liu XL, Zhou R, Pan QQ, Jia XL, Gao WN, Wu J, Lin J, Chen JF. Genetic inactivation of the adenosine A2A receptor attenuates pathologic but not developmental angiogenesis in the mouse retina. Investigative Ophthalmology & Visual Science. 51: 6625-32. PMID 20610844 DOI: 10.1167/iovs.09-4900 |
0.301 |
|
| 2010 |
Sturgess JE, Ting-A-Kee RA, Podbielski D, Sellings LH, Chen JF, van der Kooy D. Adenosine A1 and A2A receptors are not upstream of caffeine's dopamine D2 receptor-dependent aversive effects and dopamine-independent rewarding effects. The European Journal of Neuroscience. 32: 143-54. PMID 20576036 DOI: 10.1111/J.1460-9568.2010.07247.X |
0.503 |
|
| 2010 |
Goldman N, Chen M, Fujita T, Xu Q, Peng W, Liu W, Jensen TK, Pei Y, Wang F, Han X, Chen JF, Schnermann J, Takano T, Bekar L, Tieu K, et al. Adenosine A1 receptors mediate local anti-nociceptive effects of acupuncture. Nature Neuroscience. 13: 883-8. PMID 20512135 DOI: 10.1038/Nn.2562 |
0.464 |
|
| 2010 |
Dai SS, Zhou YG, Li W, An JH, Li P, Yang N, Chen XY, Xiong RP, Liu P, Zhao Y, Shen HY, Zhu PF, Chen JF. Local glutamate level dictates adenosine A2A receptor regulation of neuroinflammation and traumatic brain injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 5802-10. PMID 20410132 DOI: 10.1523/Jneurosci.0268-10.2010 |
0.448 |
|
| 2010 |
Dai SS, Li W, An JH, Wang H, Yang N, Chen XY, Zhao Y, Li P, Liu P, Chen JF, Zhou YG. Adenosine A2A receptors in both bone marrow cells and non-bone marrow cells contribute to traumatic brain injury. Journal of Neurochemistry. 113: 1536-44. PMID 20367749 DOI: 10.1111/J.1471-4159.2010.06716.X |
0.467 |
|
| 2010 |
Chen JF, Yu L, Shen HY, He JC, Wang X, Zheng R. What knock-out animals tell us about the effects of caffeine. Journal of Alzheimer's Disease : Jad. 20: S17-24. PMID 20182058 DOI: 10.3233/Jad-2010-1403 |
0.442 |
|
| 2010 |
Sehba FA, Flores R, Muller A, Friedrich V, Chen JF, Britz GW, Winn HR, Bederson JB. Adenosine A(2A) receptors in early ischemic vascular injury after subarachnoid hemorrhage. Laboratory investigation. Journal of Neurosurgery. 113: 826-34. PMID 19895201 DOI: 10.3171/2009.9.JNS09802 |
0.39 |
|
| 2010 |
Boison D, Chen JF, Fredholm BB. Adenosine signaling and function in glial cells. Cell Death and Differentiation. 17: 1071-82. PMID 19763139 DOI: 10.1038/Cdd.2009.131 |
0.356 |
|
| 2009 |
Shen HY, Chen JF. Adenosine A(2A) receptors in psychopharmacology: modulators of behavior, mood and cognition. Current Neuropharmacology. 7: 195-206. PMID 20190961 DOI: 10.2174/157015909789152191 |
0.413 |
|
| 2009 |
Yu C, Gupta J, Chen JF, Yin HH. Genetic deletion of A2A adenosine receptors in the striatum selectively impairs habit formation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 15100-3. PMID 19955361 DOI: 10.1523/JNEUROSCI.4215-09.2009 |
0.415 |
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| 2009 |
Zhou SJ, Zhu ME, Shu D, Du XP, Song XH, Wang XT, Zheng RY, Cai XH, Chen JF, He JC. Preferential enhancement of working memory in mice lacking adenosine A(2A) receptors. Brain Research. 1303: 74-83. PMID 19785999 DOI: 10.1016/J.Brainres.2009.09.082 |
0.425 |
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| 2009 |
Gui L, Duan W, Tian H, Li C, Zhu J, Chen JF, Zheng J. Adenosine A 2A receptor deficiency reduces striatal glutamate outflow and attenuates brain injury induced by transient focal cerebral ischemia in mice. Brain Research. 1297: 185-93. PMID 19703429 DOI: 10.1016/J.Brainres.2009.08.050 |
0.469 |
|
| 2009 |
Tebano MT, Martire A, Chiodi V, Pepponi R, Ferrante A, Domenici MR, Frank C, Chen JF, Ledent C, Popoli P. Adenosine A2A receptors enable the synaptic effects of cannabinoid CB1 receptors in the rodent striatum. Journal of Neurochemistry. 110: 1921-30. PMID 19627447 DOI: 10.1111/J.1471-4159.2009.06282.X |
0.45 |
|
| 2009 |
Duan W, Gui L, Zhou Z, Liu Y, Tian H, Chen JF, Zheng J. Adenosine A2A receptor deficiency exacerbates white matter lesions and cognitive deficits induced by chronic cerebral hypoperfusion in mice. Journal of the Neurological Sciences. 285: 39-45. PMID 19524941 DOI: 10.1016/J.Jns.2009.05.010 |
0.435 |
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| 2009 |
Wang H, Zhang W, Zhu C, Bucher C, Blazar BR, Zhang C, Chen JF, Linden J, Wu C, Huo Y. Inactivation of the adenosine A2A receptor protects apolipoprotein E-deficient mice from atherosclerosis. Arteriosclerosis, Thrombosis, and Vascular Biology. 29: 1046-52. PMID 19407243 DOI: 10.1161/Atvbaha.109.188839 |
0.382 |
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| 2009 |
Yu L, Coelho JE, Zhang X, Fu Y, Tillman A, Karaoz U, Fredholm BB, Weng Z, Chen JF. Uncovering multiple molecular targets for caffeine using a drug target validation strategy combining A 2A receptor knockout mice with microarray profiling. Physiological Genomics. 37: 199-210. PMID 19258493 DOI: 10.1152/Physiolgenomics.90353.2008 |
0.469 |
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| 2009 |
Yang JN, Chen JF, Fredholm BB. Physiological roles of A1 and A2A adenosine receptors in regulating heart rate, body temperature, and locomotion as revealed using knockout mice and caffeine. American Journal of Physiology. Heart and Circulatory Physiology. 296: H1141-9. PMID 19218506 DOI: 10.1152/Ajpheart.00754.2008 |
0.446 |
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| 2009 |
Yang GK, Chen JF, Kieffer TJ, Kwok YN. Regulation of somatostatin release by adenosine in the mouse stomach. The Journal of Pharmacology and Experimental Therapeutics. 329: 729-37. PMID 19208896 DOI: 10.1124/Jpet.108.146050 |
0.368 |
|
| 2009 |
Miekisiak G, Yoo K, Sandler AL, Kulik TB, Chen JF, Winn HR. The role of adenosine in hypercarbic hyperemia: in vivo and in vitro studies in adenosine 2(A) receptor knockout and wild-type mice. Journal of Neurosurgery. 110: 981-8. PMID 19199466 DOI: 10.3171/2008.8.Jns08460 |
0.492 |
|
| 2009 |
Petzer JP, Castagnoli N, Schwarzschild MA, Chen JF, Van der Schyf CJ. Dual-target-directed drugs that block monoamine oxidase B and adenosine A(2A) receptors for Parkinson's disease. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 6: 141-51. PMID 19110205 DOI: 10.1016/J.Nurt.2008.10.035 |
0.321 |
|
| 2009 |
Yang JN, Björklund O, Lindström-Törnqvist K, Lindgren E, Eriksson TM, Kahlström J, Chen JF, Schwarzschild MA, Tobler I, Fredholm BB. Mice heterozygous for both A1 and A(2A) adenosine receptor genes show similarities to mice given long-term caffeine. Journal of Applied Physiology (Bethesda, Md. : 1985). 106: 631-9. PMID 19036889 DOI: 10.1152/Japplphysiol.90971.2008 |
0.425 |
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| 2009 |
Li W, Dai S, An J, Xiong R, Li P, Chen X, Zhao Y, Liu P, Wang H, Zhu P, Chen J, Zhou Y. Genetic inactivation of adenosine A2A receptors attenuates acute traumatic brain injury in the mouse cortical impact model. Experimental Neurology. 215: 69-76. PMID 18938161 DOI: 10.1016/J.Expneurol.2008.09.012 |
0.387 |
|
| 2008 |
Miekisiak G, Kulik T, Kusano Y, Kung D, Chen JF, Winn HR. Cerebral blood flow response in adenosine 2a receptor knockout mice during transient hypoxic hypoxia. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 28: 1656-64. PMID 18545261 DOI: 10.1038/Jcbfm.2008.57 |
0.393 |
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| 2008 |
Cunha RA, Ferré S, Vaugeois JM, Chen JF. Potential therapeutic interest of adenosine A2A receptors in psychiatric disorders. Current Pharmaceutical Design. 14: 1512-24. PMID 18537674 DOI: 10.2174/138161208784480090 |
0.511 |
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| 2008 |
Chen JF, Pedata F. Modulation of ischemic brain injury and neuroinflammation by adenosine A2A receptors. Current Pharmaceutical Design. 14: 1490-9. PMID 18537672 DOI: 10.2174/138161208784480126 |
0.343 |
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| 2008 |
Shen HY, Coelho JE, Ohtsuka N, Canas PM, Day YJ, Huang QY, Rebola N, Yu L, Boison D, Cunha RA, Linden J, Tsien JZ, Chen JF. A critical role of the adenosine A2A receptor in extrastriatal neurons in modulating psychomotor activity as revealed by opposite phenotypes of striatum and forebrain A2A receptor knock-outs. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 2970-5. PMID 18354001 DOI: 10.1523/Jneurosci.5255-07.2008 |
0.384 |
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| 2008 |
Yu L, Shen HY, Coelho JE, Araújo IM, Huang QY, Day YJ, Rebola N, Canas PM, Rapp EK, Ferrara J, Taylor D, Müller CE, Linden J, Cunha RA, Chen JF. Adenosine A2A receptor antagonists exert motor and neuroprotective effects by distinct cellular mechanisms. Annals of Neurology. 63: 338-46. PMID 18300283 DOI: 10.1002/Ana.21313 |
0.477 |
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| 2008 |
Tikh EI, Fenton RA, Chen JF, Schwarzschild MA, Dobson JG. Adenosine A1 and A2A receptor regulation of protein phosphatase 2A in the murine heart. Journal of Cellular Physiology. 216: 83-90. PMID 18181173 DOI: 10.1002/Jcp.21375 |
0.446 |
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| 2007 |
Dong F, An JH, Ren YP, Yan DS, Zhou XT, Lü F, Hu DN, Chen JF, Qu J. [Expression of dopamine receptor D2 and adenosine receptor A2A in human retinal pigment epithelium]. [Zhonghua Yan Ke Za Zhi] Chinese Journal of Ophthalmology. 43: 1110-3. PMID 18331682 DOI: 10.3760/J.Issn:0412-4081.2007.12.013 |
0.402 |
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| 2007 |
Chen JF, Sonsalla PK, Pedata F, Melani A, Domenici MR, Popoli P, Geiger J, Lopes LV, de Mendonça A. Adenosine A2A receptors and brain injury: broad spectrum of neuroprotection, multifaceted actions and "fine tuning" modulation. Progress in Neurobiology. 83: 310-31. PMID 18023959 DOI: 10.1016/J.Pneurobio.2007.09.002 |
0.338 |
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| 2007 |
Yee BK, Singer P, Chen JF, Feldon J, Boison D. Transgenic overexpression of adenosine kinase in brain leads to multiple learning impairments and altered sensitivity to psychomimetic drugs. The European Journal of Neuroscience. 26: 3237-52. PMID 18005073 DOI: 10.1111/J.1460-9568.2007.05897.X |
0.503 |
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| 2007 |
Björklund O, Kahlström J, Salmi P, Ogren SO, Vahter M, Chen JF, Fredholm BB, Daré E. The effects of methylmercury on motor activity are sex- and age-dependent, and modulated by genetic deletion of adenosine receptors and caffeine administration. Toxicology. 241: 119-33. PMID 17920182 DOI: 10.1016/J.Tox.2007.08.092 |
0.513 |
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| 2007 |
Mohsenin A, Mi T, Xia Y, Kellems RE, Chen JF, Blackburn MR. Genetic removal of the A2A adenosine receptor enhances pulmonary inflammation, mucin production, and angiogenesis in adenosine deaminase-deficient mice. American Journal of Physiology. Lung Cellular and Molecular Physiology. 293: L753-61. PMID 17601796 DOI: 10.1152/Ajplung.00187.2007 |
0.375 |
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| 2007 |
Huang QY, Yu L, Ferrante RJ, Chen JF. Mutant SOD1G93A in bone marrow-derived cells exacerbates 3-nitropropionic acid induced striatal damage in mice. Neuroscience Letters. 418: 175-80. PMID 17418947 DOI: 10.1016/J.Neulet.2007.03.038 |
0.31 |
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| 2007 |
Coelho JE, Shen HY, Goldstein KR, Chen JF. What animal models have taught us about adenosine receptor function Immunology, Endocrine and Metabolic Agents in Medicinal Chemistry. 7: 328-340. DOI: 10.2174/187152207781369869 |
0.47 |
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| 2007 |
Tang R, Wang H, Chen J, Linden J. Leukocyte adenosine A2A receptor activation inhibits leukocyte‐endothelial interactions in vivo The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A127 |
0.396 |
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| 2006 |
Xiao D, Bastia E, Xu YH, Benn CL, Cha JH, Peterson TS, Chen JF, Schwarzschild MA. Forebrain adenosine A2A receptors contribute to L-3,4-dihydroxyphenylalanine-induced dyskinesia in hemiparkinsonian mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 13548-55. PMID 17192438 DOI: 10.1523/Jneurosci.3554-06.2006 |
0.405 |
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| 2006 |
Huang QY, Wei C, Yu L, Coelho JE, Shen HY, Kalda A, Linden J, Chen JF. Adenosine A2A receptors in bone marrow-derived cells but not in forebrain neurons are important contributors to 3-nitropropionic acid-induced striatal damage as revealed by cell-type-selective inactivation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 11371-8. PMID 17079665 DOI: 10.1523/Jneurosci.1907-06.2006 |
0.748 |
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| 2006 |
Schwarzschild MA, Agnati L, Fuxe K, Chen JF, Morelli M. Targeting adenosine A2A receptors in Parkinson's disease. Trends in Neurosciences. 29: 647-54. PMID 17030429 DOI: 10.1016/J.Tins.2006.09.004 |
0.436 |
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| 2006 |
Kalda A, Yu L, Oztas E, Chen JF. Novel neuroprotection by caffeine and adenosine A(2A) receptor antagonists in animal models of Parkinson's disease. Journal of the Neurological Sciences. 248: 9-15. PMID 16806272 DOI: 10.1016/j.jns.2006.05.003 |
0.411 |
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| 2006 |
Seeman P, Schwarz J, Chen JF, Szechtman H, Perreault M, McKnight GS, Roder JC, Quirion R, Boksa P, Srivastava LK, Yanai K, Weinshenker D, Sumiyoshi T. Psychosis pathways converge via D2high dopamine receptors. Synapse (New York, N.Y.). 60: 319-46. PMID 16786561 DOI: 10.1002/Syn.20303 |
0.331 |
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| 2006 |
Chan ES, Montesinos MC, Fernandez P, Desai A, Delano DL, Yee H, Reiss AB, Pillinger MH, Chen JF, Schwarzschild MA, Friedman SL, Cronstein BN. Adenosine A(2A) receptors play a role in the pathogenesis of hepatic cirrhosis. British Journal of Pharmacology. 148: 1144-55. PMID 16783407 DOI: 10.1038/Sj.Bjp.0706812 |
0.48 |
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| 2006 |
Bilbao A, Cippitelli A, MartÃn AB, Granado N, Ortiz O, Bezard E, Chen JF, Navarro M, RodrÃguez de Fonseca F, Moratalla R. Absence of quasi-morphine withdrawal syndrome in adenosine A2A receptor knockout mice. Psychopharmacology. 185: 160-8. PMID 16470403 DOI: 10.1007/S00213-005-0284-0 |
0.482 |
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| 2006 |
Xu K, Xu Y, Brown-Jermyn D, Chen JF, Ascherio A, Dluzen DE, Schwarzschild MA. Estrogen prevents neuroprotection by caffeine in the mouse 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 535-41. PMID 16407551 DOI: 10.1523/Jneurosci.3008-05.2006 |
0.339 |
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| 2005 |
Kachroo A, Orlando LR, Grandy DK, Chen JF, Young AB, Schwarzschild MA. Interactions between metabotropic glutamate 5 and adenosine A2A receptors in normal and parkinsonian mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 10414-9. PMID 16280580 DOI: 10.1523/Jneurosci.3660-05.2005 |
0.376 |
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| 2005 |
Saura J, Angulo E, Ejarque A, Casadó V, Tusell JM, Moratalla R, Chen JF, Schwarzschild MA, Lluis C, Franco R, Serratosa J. Adenosine A2A receptor stimulation potentiates nitric oxide release by activated microglia. Journal of Neurochemistry. 95: 919-29. PMID 16092928 DOI: 10.1111/J.1471-4159.2005.03395.X |
0.423 |
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| 2005 |
Yu L, Haverty PM, Mariani J, Wang Y, Shen HY, Schwarzschild MA, Weng Z, Chen JF. Genetic and pharmacological inactivation of adenosine A2A receptor reveals an Egr-2-mediated transcriptional regulatory network in the mouse striatum. Physiological Genomics. 23: 89-102. PMID 16046619 DOI: 10.1152/Physiolgenomics.00068.2005 |
0.378 |
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| 2005 |
Huang ZL, Qu WM, Eguchi N, Chen JF, Schwarzschild MA, Fredholm BB, Urade Y, Hayaishi O. Adenosine A2A, but not A1, receptors mediate the arousal effect of caffeine. Nature Neuroscience. 8: 858-9. PMID 15965471 DOI: 10.1038/Nn1491 |
0.527 |
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| 2005 |
Fredholm BB, Chen JF, Masino SA, Vaugeois JM. Actions of adenosine at its receptors in the CNS: insights from knockouts and drugs. Annual Review of Pharmacology and Toxicology. 45: 385-412. PMID 15822182 DOI: 10.1146/Annurev.Pharmtox.45.120403.095731 |
0.384 |
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| 2005 |
Fredholm BB, Chen JF, Cunha RA, Svenningsson P, Vaugeois JM. Adenosine and brain function. International Review of Neurobiology. 63: 191-270. PMID 15797469 DOI: 10.1016/S0074-7742(05)63007-3 |
0.488 |
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| 2005 |
Bastia E, Xu YH, Scibelli AC, Day YJ, Linden J, Chen JF, Schwarzschild MA. A crucial role for forebrain adenosine A(2A) receptors in amphetamine sensitization. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 30: 891-900. PMID 15602504 DOI: 10.1038/Sj.Npp.1300630 |
0.393 |
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| 2004 |
Yu L, Huang Z, Mariani J, Wang Y, Moskowitz M, Chen JF. Selective inactivation or reconstitution of adenosine A2A receptors in bone marrow cells reveals their significant contribution to the development of ischemic brain injury. Nature Medicine. 10: 1081-7. PMID 15448683 DOI: 10.1038/nm1103 |
0.341 |
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| 2004 |
Fink JS, Kalda A, Ryu H, Stack EC, Schwarzschild MA, Chen JF, Ferrante RJ. Genetic and pharmacological inactivation of the adenosine A2A receptor attenuates 3-nitropropionic acid-induced striatal damage. Journal of Neurochemistry. 88: 538-44. PMID 14720203 DOI: 10.1046/J.1471-4159.2003.02145.X |
0.353 |
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| 2004 |
Sakata M, Eguchi N, Qu WM, Huang ZL, Chen JF, Schwarzschild MA, Urade Y, Hayaishi O. Lack of rebound of non-rapid eye movement sleep after sleep deprivation in adenosine A2A receptor knockout mice Sleep and Biological Rhythms. 2: S56. DOI: 10.1111/J.1479-8425.2004.00115.X |
0.325 |
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| 2004 |
Qu WM, Huang ZL, Mochizuki T, Eguchi N, Chen JF, Schwarzschild MA, Fink SJ, Urade Y, Hayaishi O. Adenosine A2A receptor deficiency attenuates the somnogenic effect of prostaglandin D2 Sleep and Biological Rhythms. 2: S55. DOI: 10.1111/J.1479-8425.2004.00114.X |
0.402 |
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| 2004 |
Chen J, Schwarzschild MA. Adenosine A2A receptors and neuroadaptation: Possible implications in sleep-wake physiology Sleep and Biological Rhythms. 2. DOI: 10.1111/J.1479-8425.2004.00093.X |
0.356 |
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| 2003 |
Urade Y, Eguchi N, Qu WM, Sakata M, Huang ZL, Chen JF, Schwarzschild MA, Fink JS, Hayaishi O. Sleep regulation in adenosine A2A receptor-deficient mice. Neurology. 61: S94-6. PMID 14663019 DOI: 10.1212/01.Wnl.0000095222.41066.5E |
0.357 |
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| 2003 |
Chen JF, Fredduzzi S, Bastia E, Yu L, Moratalla R, Ongini E, Schwarzschild MA. Adenosine A2A receptors in neuroadaptation to repeated dopaminergic stimulation: implications for the treatment of dyskinesias in Parkinson's disease. Neurology. 61: S74-81. PMID 14663016 DOI: 10.1212/01.Wnl.0000095218.26363.7B |
0.344 |
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| 2003 |
Castagnoli N, Petzer JP, Steyn S, Castagnoli K, Chen JF, Schwarzschild MA, Van der Schyf CJ. Monoamine oxidase B inhibition and neuroprotection: studies on selective adenosine A2A receptor antagonists. Neurology. 61: S62-8. PMID 14663013 DOI: 10.1212/01.Wnl.0000095215.97585.59 |
0.372 |
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| 2003 |
Schwarzschild MA, Xu K, Oztas E, Petzer JP, Castagnoli K, Castagnoli N, Chen JF. Neuroprotection by caffeine and more specific A2A receptor antagonists in animal models of Parkinson's disease. Neurology. 61: S55-61. PMID 14663012 DOI: 10.1212/01.Wnl.0000095214.53646.72 |
0.403 |
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| 2003 |
Chen J, Chase T, Schwarzschild M. J. Stephen Fink, MD, PhD (1950–2002) Neurology. 61. PMID 14663000 DOI: 10.1212/01.Wnl.0000095201.55121.8A |
0.33 |
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| 2003 |
Day YJ, Huang L, McDuffie MJ, Rosin DL, Ye H, Chen JF, Schwarzschild MA, Fink JS, Linden J, Okusa MD. Renal protection from ischemia mediated by A2A adenosine receptors on bone marrow-derived cells. The Journal of Clinical Investigation. 112: 883-91. PMID 12975473 DOI: 10.1172/Jci15483 |
0.356 |
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| 2003 |
Chen JF, Moratalla R, Yu L, MartÃn AB, Xu K, Bastia E, Hackett E, Alberti I, Schwarzschild MA. Inactivation of adenosine A2A receptors selectively attenuates amphetamine-induced behavioral sensitization. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 28: 1086-95. PMID 12700712 DOI: 10.1038/Sj.Npp.1300152 |
0.388 |
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| 2003 |
Petzer JP, Steyn S, Castagnoli KP, Chen JF, Schwarzschild MA, Van der Schyf CJ, Castagnoli N. Inhibition of monoamine oxidase B by selective adenosine A2A receptor antagonists. Bioorganic & Medicinal Chemistry. 11: 1299-310. PMID 12628657 DOI: 10.1016/S0968-0896(02)00648-X |
0.342 |
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| 2003 |
Montesinos MC, Desai A, Delano D, Chen JF, Fink JS, Jacobson MA, Cronstein BN. Adenosine A2A or A3 receptors are required for inhibition of inflammation by methotrexate and its analog MX-68. Arthritis and Rheumatism. 48: 240-7. PMID 12528125 DOI: 10.1002/Art.10712 |
0.387 |
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| 2003 |
Schwarzschild MA, Chen JF, Chase TN. A2A antagonists for PD: A prime example of translational neuroscience Neurology. 61: S3-S4. DOI: 10.1212/01.Wnl.0000095202.94814.0F |
0.389 |
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| 2002 |
Chen JF, Steyn S, Staal R, Petzer JP, Xu K, Van Der Schyf CJ, Castagnoli K, Sonsalla PK, Castagnoli N, Schwarzschild MA. 8-(3-Chlorostyryl)caffeine may attenuate MPTP neurotoxicity through dual actions of monoamine oxidase inhibition and A2A receptor antagonism. The Journal of Biological Chemistry. 277: 36040-4. PMID 12130655 DOI: 10.1074/Jbc.M206830200 |
0.401 |
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| 2002 |
Leibovich SJ, Chen JF, Pinhal-Enfield G, Belem PC, Elson G, Rosania A, Ramanathan M, Montesinos C, Jacobson M, Schwarzschild MA, Fink JS, Cronstein B. Synergistic up-regulation of vascular endothelial growth factor expression in murine macrophages by adenosine A(2A) receptor agonists and endotoxin. The American Journal of Pathology. 160: 2231-44. PMID 12057925 DOI: 10.1016/S0002-9440(10)61170-4 |
0.33 |
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| 2002 |
Montesinos MC, Desai A, Chen JF, Yee H, Schwarzschild MA, Fink JS, Cronstein BN. Adenosine promotes wound healing and mediates angiogenesis in response to tissue injury via occupancy of A(2A) receptors. The American Journal of Pathology. 160: 2009-18. PMID 12057906 DOI: 10.1016/S0002-9440(10)61151-0 |
0.37 |
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| 2002 |
Schwarzschild MA, Chen J, Ascherio A. Caffeinated clues and the promise of adenosine A2A antagonists in PD Neurology. 58: 1154-1160. PMID 11971080 DOI: 10.1212/Wnl.58.8.1154 |
0.368 |
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| 2002 |
Fredduzzi S, Moratalla R, Monopoli A, Cuellar B, Xu K, Ongini E, Impagnatiello F, Schwarzschild MA, Chen JF. Persistent behavioral sensitization to chronic L-DOPA requires A2A adenosine receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 1054-62. PMID 11826134 DOI: 10.1523/Jneurosci.22-03-01054.2002 |
0.383 |
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| 2000 |
Apasov S, Chen J, Smith P, Sitkovsky M. A2A receptor dependent and A2A receptor independent effects of extracellular adenosine on murine thymocytes in conditions of adenosine deaminase deficiency Blood. 95: 3859-3867. DOI: 10.1182/Blood.V95.12.3859.012K48_3859_3867 |
0.45 |
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