| Year |
Citation |
Score |
| 2024 |
Bah TM, Davis CM, Allen E, Borkar RN, Perez R, Grafe MR, Raber J, Pike MM, Alkayed NJ. Soluble Epoxide Hydrolase Inhibition Reverses Cognitive Dysfunction in a Mouse Model of Metabolic Syndrome by Modulating Inflammation. Prostaglandins & Other Lipid Mediators. 106850. PMID 38735559 DOI: 10.1016/j.prostaglandins.2024.106850 |
0.374 |
|
| 2023 |
Davis CM, Ammi AY, Zhu W, Methner C, Cao Z, Giraud D, Alkayed NJ, Woltjer RL, Kaul S. Low-Intensity Ultrasound Reduces Brain Infarct Size by Upregulating Phosphorylated Endothelial Nitric Oxide in Mouse Model of Middle Cerebral Artery Occlusion. Ultrasound in Medicine & Biology. PMID 36739244 DOI: 10.1016/j.ultrasmedbio.2022.12.008 |
0.329 |
|
| 2023 |
Zhu W, Davis CM, Allen EM, Feller SL, Bah TM, Shangraw RE, Wang RK, Alkayed NJ. Sex Difference in Capillary Reperfusion After Transient Middle Cerebral Artery Occlusion in Diabetic Mice. Stroke. 54: 364-373. PMID 36689578 DOI: 10.1161/STROKEAHA.122.040972 |
0.413 |
|
| 2022 |
Davis CM, Lyon-Scott K, Varlamov EV, Zhang WH, Alkayed NJ. Role of Endothelial STAT3 in Cerebrovascular Function and Protection from Ischemic Brain Injury. International Journal of Molecular Sciences. 23. PMID 36293020 DOI: 10.3390/ijms232012167 |
0.344 |
|
| 2022 |
Xu Y, Zhang WH, Allen EM, Fedorov LM, Barnes AP, Qian ZY, Bah TM, Li Y, Wang RK, Shangraw RE, Alkayed NJ. GPR39 Knockout Worsens Microcirculatory Response to Experimental Stroke in a Sex-Dependent Manner. Translational Stroke Research. PMID 36181628 DOI: 10.1007/s12975-022-01093-6 |
0.387 |
|
| 2022 |
Davis CM, Zhang WH, Bah TM, Roese NE, Allen EM, Leung P, Boutros SJ, Marzulla T, Patel E, Nie X, Alkayed FN, Huang JH, Jensen MA, Raber J, Pike MM, ... Alkayed NJ, et al. Age-dependent cognitive impairment, hydrocephalus and leukocyte infiltration in transgenic mice with endothelial expression of human EPHX2. Npj Aging. 8: 9. PMID 35927273 DOI: 10.1038/s41514-022-00090-1 |
0.356 |
|
| 2022 |
Bah TM, Allen EM, Garcia-Jaramillo M, Perez R, Zarnegarnia Y, Davis CM, Bloom MB, Magana AA, Choi J, Bobe G, Pike MM, Raber J, Maier CS, Alkayed NJ. GPR39 Deficiency Impairs Memory and Alters Oxylipins and Inflammatory Cytokines Without Affecting Cerebral Blood Flow in a High-Fat Diet Mouse Model of Cognitive Impairment. Frontiers in Cellular Neuroscience. 16: 893030. PMID 35875352 DOI: 10.3389/fncel.2022.893030 |
0.391 |
|
| 2021 |
Davis CM, Zhang WH, Allen EM, Bah TM, Shangraw RE, Alkayed NJ. Soluble Epoxide Hydrolase Blockade after Stroke Onset Protects Normal but Not Diabetic Mice. International Journal of Molecular Sciences. 22. PMID 34063817 DOI: 10.3390/ijms22115419 |
0.451 |
|
| 2019 |
Seifert HA, Zhu W, Vandenbark AA, Alkayed NJ, Offner H. Sex differences in the therapeutic effects of anti-PDL2 neutralizing antibody on stroke. Metabolic Brain Disease. PMID 31410774 DOI: 10.1007/S11011-019-00476-3 |
0.339 |
|
| 2016 |
Jia J, Davis CM, Zhang W, Edin ML, Jouihan S, Jia T, Bradbury JA, Graves JP, DeGraff LM, Lee CR, Ronnekleiv O, Wang R, Xu Y, Zeldin DC, Alkayed NJ. Sex- and isoform-specific mechanism of neuroprotection by transgenic expression of P450 epoxygenase in vascular endothelium. Experimental Neurology. PMID 26902473 DOI: 10.1016/J.Expneurol.2016.02.016 |
0.373 |
|
| 2016 |
Johnson LA, Zuloaga KL, Kugelman TL, Mader KS, Morré JT, Zuloaga DG, Weber S, Marzulla T, Mulford A, Button D, Lindner JR, Alkayed NJ, Stevens JF, Raber J. Amelioration of Metabolic Syndrome-Associated Cognitive Impairments in Mice via a Reduction in Dietary Fat Content or Infusion of Non-Diabetic Plasma. Ebiomedicine. 3: 26-42. PMID 26870815 DOI: 10.1016/J.Ebiom.2015.12.008 |
0.638 |
|
| 2015 |
Zuloaga KL, Johnson LA, Roese NE, Marzulla T, Zhang W, Nie X, Alkayed FN, Hong C, Grafe MR, Pike MM, Raber J, Alkayed NJ. High fat diet-induced diabetes in mice exacerbates cognitive deficit due to chronic hypoperfusion. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. PMID 26661233 DOI: 10.1177/0271678X15616400 |
0.653 |
|
| 2015 |
Chen Y, Zhu W, Zhang W, Libal N, Murphy SJ, Offner H, Alkayed NJ. A Novel Mouse Model of Thromboembolic Stroke. Journal of Neuroscience Methods. PMID 26386284 DOI: 10.1016/J.Jneumeth.2015.09.013 |
0.396 |
|
| 2015 |
Zuloaga KL, Zhang W, Yeiser LA, Stewart B, Kukino A, Nie X, Roese NE, Grafe MR, Pike MM, Raber J, Alkayed NJ. Neurobehavioral and Imaging Correlates of Hippocampal Atrophy in a Mouse Model of Vascular Cognitive Impairment. Translational Stroke Research. PMID 26040424 DOI: 10.1007/S12975-015-0412-Z |
0.662 |
|
| 2015 |
Siler DA, Berlow YA, Kukino A, Davis CM, Nelson JW, Grafe MR, Ono H, Cetas JS, Pike M, Alkayed NJ. Soluble Epoxide Hydrolase in Hydrocephalus, Cerebral Edema, and Vascular Inflammation After Subarachnoid Hemorrhage. Stroke; a Journal of Cerebral Circulation. 46: 1916-22. PMID 25991416 DOI: 10.1161/Strokeaha.114.008560 |
0.306 |
|
| 2015 |
Zhu W, Dotson AL, Libal NL, Lapato AS, Bodhankar S, Offner H, Alkayed NJ. Recombinant T-cell receptor ligand RTL1000 limits inflammation and decreases infarct size after experimental ischemic stroke in middle-aged mice. Neuroscience. 288: 112-9. PMID 25556831 DOI: 10.1016/J.Neuroscience.2014.12.037 |
0.369 |
|
| 2015 |
Zhu W, Casper A, Libal NL, Murphy SJ, Bodhankar S, Offner H, Alkayed NJ. Preclinical evaluation of recombinant T cell receptor ligand RTL1000 as a therapeutic agent in ischemic stroke. Translational Stroke Research. 6: 60-8. PMID 25270354 DOI: 10.1007/S12975-014-0373-7 |
0.302 |
|
| 2015 |
Siler DA, Martini RP, Ward JP, Nelson JW, Borkar RN, Zuloaga KL, Liu JJ, Fairbanks SL, Raskin JS, Anderson VC, Dogan A, Wang RK, Alkayed NJ, Cetas JS. Protective role of p450 epoxyeicosanoids in subarachnoid hemorrhage. Neurocritical Care. 22: 306-19. PMID 25231529 DOI: 10.1007/S12028-014-0011-Y |
0.604 |
|
| 2014 |
Zuloaga KL, Zhang W, Roese NE, Alkayed NJ. Soluble epoxide hydrolase gene deletion improves blood flow and reduces infarct size after cerebral ischemia in reproductively senescent female mice. Frontiers in Pharmacology. 5: 290. PMID 25642188 DOI: 10.3389/Fphar.2014.00290 |
0.674 |
|
| 2014 |
Nelson JW, Young JM, Borkar RN, Woltjer RL, Quinn JF, Silbert LC, Grafe MR, Alkayed NJ. Role of soluble epoxide hydrolase in age-related vascular cognitive decline. Prostaglandins & Other Lipid Mediators. 113: 30-7. PMID 25277097 DOI: 10.1016/j.prostaglandins.2014.09.003 |
0.302 |
|
| 2014 |
Martini RP, Ward J, Siler DA, Eastman JM, Nelson JW, Borkar RN, Alkayed NJ, Dogan A, Cetas JS. Genetic variation in soluble epoxide hydrolase: association with outcome after aneurysmal subarachnoid hemorrhage. Journal of Neurosurgery. 121: 1359-66. PMID 25216066 DOI: 10.3171/2014.7.Jns131990 |
0.319 |
|
| 2014 |
Zhu W, Libal NL, Casper A, Bodhankar S, Offner H, Alkayed NJ. Recombinant T cell receptor ligand treatment improves neurological outcome in the presence of tissue plasminogen activator in experimental ischemic stroke. Translational Stroke Research. 5: 612-7. PMID 24953050 DOI: 10.1007/S12975-014-0348-8 |
0.311 |
|
| 2014 |
Hutchens MP, Kosaka Y, Zhang W, Fujiyoshi T, Murphy S, Alkayed N, Anderson S. Estrogen-mediated renoprotection following cardiac arrest and cardiopulmonary resuscitation is robust to GPR30 gene deletion. Plos One. 9: e99910. PMID 24923556 DOI: 10.1371/Journal.Pone.0099910 |
0.304 |
|
| 2014 |
Zuloaga KL, Krasnow SM, Zhu X, Zhang W, Jouihan SA, Shangraw RE, Alkayed NJ, Marks DL. Mechanism of protection by soluble epoxide hydrolase inhibition in type 2 diabetic stroke. Plos One. 9: e97529. PMID 24824753 DOI: 10.1371/Journal.Pone.0097529 |
0.683 |
|
| 2014 |
Zuloaga KL, Davis CM, Zhang W, Alkayed NJ. Role of aromatase in sex-specific cerebrovascular endothelial function in mice. American Journal of Physiology. Heart and Circulatory Physiology. 306: H929-37. PMID 24508640 DOI: 10.1152/Ajpheart.00698.2013 |
0.643 |
|
| 2013 |
Jouihan SA, Zuloaga KL, Zhang W, Shangraw RE, Krasnow SM, Marks DL, Alkayed NJ. Role of soluble epoxide hydrolase in exacerbation of stroke by streptozotocin-induced type 1 diabetes mellitus. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 33: 1650-6. PMID 23899929 DOI: 10.1038/Jcbfm.2013.130 |
0.681 |
|
| 2013 |
Zhang W, Davis CM, Edin ML, Lee CR, Zeldin DC, Alkayed NJ. Role of endothelial soluble epoxide hydrolase in cerebrovascular function and ischemic injury. Plos One. 8: e61244. PMID 23585883 DOI: 10.1371/journal.pone.0061244 |
0.453 |
|
| 2012 |
Di Domenico F, Casalena G, Jia J, Sultana R, Barone E, Cai J, Pierce WM, Cini C, Mancuso C, Perluigi M, Davis CM, Alkayed NJ, Butterfield DA, Butterfield AD. Sex differences in brain proteomes of neuron-specific STAT3-null mice after cerebral ischemia/reperfusion. Journal of Neurochemistry. 121: 680-92. PMID 22394374 DOI: 10.1111/J.1471-4159.2012.07721.X |
0.314 |
|
| 2012 |
Domenico FD, Casalena G, Jia J, Sultana R, Barone E, Cai J, Pierce WM, Cini C, Mancuso C, Perluigi M, Davis C, Alkayed N, Butterfield AD. Erratum: Sex differences in brain proteomes of neuron-specific STAT3-null mice after cerebral ischemia/reperfusion (Journal of Neurochemistry (2012) 121 (680-692) Journal of Neurochemistry. 122: 1093. DOI: 10.1111/J.1471-4159.2012.07854.X |
0.451 |
|
| 2011 |
Jia Y, Grafe MR, Gruber A, Alkayed NJ, Wang RK. In vivo optical imaging of revascularization after brain trauma in mice. Microvascular Research. 81: 73-80. PMID 21075124 DOI: 10.1016/j.mvr.2010.11.003 |
0.316 |
|
| 2009 |
Iliff JJ, Alkayed NJ. Soluble Epoxide Hydrolase Inhibition: Targeting Multiple Mechanisms of Ischemic Brain Injury with a Single Agent. Future Neurology. 4: 179-199. PMID 19779591 DOI: 10.2217/14796708.4.2.179 |
0.314 |
|
| 2009 |
Cetas JS, Lee DR, Alkayed NJ, Wang R, Iliff JJ, Heinricher MM. Brainstem control of cerebral blood flow and application to acute vasospasm following experimental subarachnoid hemorrhage. Neuroscience. 163: 719-29. PMID 19539726 DOI: 10.1016/J.Neuroscience.2009.06.031 |
0.32 |
|
| 2009 |
Zhang W, Iliff JJ, Campbell CJ, Wang RK, Hurn PD, Alkayed NJ. Role of soluble epoxide hydrolase in the sex-specific vascular response to cerebral ischemia. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 29: 1475-81. PMID 19471280 DOI: 10.1038/jcbfm.2009.65 |
0.412 |
|
| 2009 |
Jia J, Guan D, Zhu W, Alkayed NJ, Wang MM, Hua Z, Xu Y. Estrogen inhibits Fas-mediated apoptosis in experimental stroke. Experimental Neurology. 215: 48-52. PMID 18950622 DOI: 10.1016/j.expneurol.2008.09.015 |
0.314 |
|
| 2008 |
Motoki A, Merkel MJ, Packwood WH, Cao Z, Liu L, Iliff J, Alkayed NJ, Van Winkle DM. Soluble epoxide hydrolase inhibition and gene deletion are protective against myocardial ischemia-reperfusion injury in vivo. American Journal of Physiology. Heart and Circulatory Physiology. 295: H2128-34. PMID 18835921 DOI: 10.1152/ajpheart.00428.2008 |
0.324 |
|
| 2008 |
Liu X, Zhang W, Alkayed NJ, Froehner SC, Adams ME, Amiry-Moghaddam M, Ottersen OP, Hurn PD, Bhardwaj A. Lack of sex-linked differences in cerebral edema and aquaporin-4 expression after experimental stroke. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 28: 1898-906. PMID 18648381 DOI: 10.1038/jcbfm.2008.83 |
0.356 |
|
| 2008 |
Zhang W, Otsuka T, Sugo N, Ardeshiri A, Alhadid YK, Iliff JJ, DeBarber AE, Koop DR, Alkayed NJ. Soluble epoxide hydrolase gene deletion is protective against experimental cerebral ischemia. Stroke; a Journal of Cerebral Circulation. 39: 2073-8. PMID 18369166 DOI: 10.1161/Strokeaha.107.508325 |
0.305 |
|
| 2008 |
Hutchens MP, Nakano T, Dunlap J, Traystman RJ, Hurn PD, Alkayed NJ. Soluble epoxide hydrolase gene deletion reduces survival after cardiac arrest and cardiopulmonary resuscitation. Resuscitation. 76: 89-94. PMID 17728042 DOI: 10.1016/j.resuscitation.2007.06.031 |
0.306 |
|
| 2007 |
Iliff JJ, Close LN, Selden NR, Alkayed NJ. A novel role for P450 eicosanoids in the neurogenic control of cerebral blood flow in the rat. Experimental Physiology. 92: 653-8. PMID 17639071 DOI: 10.1113/expphysiol.2006.036889 |
0.305 |
|
| 2007 |
Koerner IP, Jacks R, DeBarber AE, Koop D, Mao P, Grant DF, Alkayed NJ. Polymorphisms in the human soluble epoxide hydrolase gene EPHX2 linked to neuronal survival after ischemic injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 4642-9. PMID 17460077 DOI: 10.1097/00008506-200610000-00099 |
0.333 |
|
| 2007 |
Zhang W, Koerner IP, Noppens R, Grafe M, Tsai HJ, Morisseau C, Luria A, Hammock BD, Falck JR, Alkayed NJ. Soluble epoxide hydrolase: a novel therapeutic target in stroke. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 27: 1931-40. PMID 17440491 DOI: 10.1038/Sj.Jcbfm.9600494 |
0.405 |
|
| 2007 |
Cheng J, Alkayed NJ, Hurn PD. Deleterious effects of dihydrotestosterone on cerebral ischemic injury. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 27: 1553-62. PMID 17311081 DOI: 10.1038/sj.jcbfm.9600457 |
0.325 |
|
| 2005 |
Koerner IP, Zhang W, Hurn PD, Koop D, Alkayed NJ. Soluble epoxide hydrolase gene deletion reduces inflammation after stroke Journal of Cerebral Blood Flow & Metabolism. 25: S93-S93. DOI: 10.1038/Sj.Jcbfm.9591524.0093 |
0.326 |
|
| 2003 |
Goto S, Sampei K, Alkayed NJ, Doré S, Koehler RC. Characterization of a new double-filament model of focal cerebral ischemia in heme oxygenase-2-deficient mice. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 285: R222-30. PMID 12663258 DOI: 10.1152/ajpregu.00067.2003 |
0.372 |
|
| 2001 |
DeVries AC, Joh HD, Bernard O, Hattori K, Hurn PD, Traystman RJ, Alkayed NJ. Social stress exacerbates stroke outcome by suppressing Bcl-2 expression. Proceedings of the National Academy of Sciences of the United States of America. 98: 11824-8. PMID 11553785 DOI: 10.1073/pnas.201215298 |
0.323 |
|
| 2001 |
McCullough LD, Alkayed NJ, Traystman RJ, Williams MJ, Hurn PD. Postischemic estrogen reduces hypoperfusion and secondary ischemia after experimental stroke. Stroke; a Journal of Cerebral Circulation. 32: 796-802. PMID 11239204 DOI: 10.1161/01.Str.32.3.796 |
0.305 |
|
| 2001 |
Vannucci SJ, Willing LB, Goto S, Alkayed NJ, Brucklacher RM, Wood TL, Towfighi J, Hurn PD, Simpson IA. Experimental stroke in the female diabetic, db/db, mouse. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 21: 52-60. PMID 11149668 DOI: 10.1097/00004647-200101000-00007 |
0.378 |
|
| 2000 |
Sampei K, Goto S, Alkayed NJ, Crain BJ, Korach KS, Traystman RJ, Demas GE, Nelson RJ, Hurn PD. Stroke in estrogen receptor-alpha-deficient mice. Stroke; a Journal of Cerebral Circulation. 31: 738-43; discussion 7. PMID 10700513 DOI: 10.1161/01.Str.31.3.738 |
0.356 |
|
| 2000 |
Sawada M, Alkayed NJ, Goto S, Crain BJ, Traystman RJ, Shaivitz A, Nelson RJ, Hurn PD. Estrogen receptor antagonist ICI182,780 exacerbates ischemic injury in female mouse. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 20: 112-8. PMID 10616799 DOI: 10.1097/00004647-200001000-00015 |
0.356 |
|
| 1999 |
Doré S, Sampei K, Goto S, Alkayed NJ, Guastella D, Blackshaw S, Gallagher M, Traystman RJ, Hurn PD, Koehler RC, Snyder SH. Heme oxygenase-2 is neuroprotective in cerebral ischemia. Molecular Medicine (Cambridge, Mass.). 5: 656-63. PMID 10602774 DOI: 10.1007/BF03401984 |
0.307 |
|
| 1999 |
Rusa R, Alkayed NJ, Crain BJ, Traystman RJ, Kimes AS, London ED, Klaus JA, Hurn PD. 17beta-estradiol reduces stroke injury in estrogen-deficient female animals. Stroke; a Journal of Cerebral Circulation. 30: 1665-70. PMID 10436119 DOI: 10.1161/01.Str.30.8.1665 |
0.308 |
|
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