| Year |
Citation |
Score |
| 2019 |
Wattanavanitchakorn S, Ansari IH, El Azzouny M, Longacre MJ, Stoker SW, Jitrapakdee S, MacDonald MJ. Differential contribution of pyruvate carboxylation to anaplerosis and cataplerosis during non-gluconeogenic and gluconeogenic conditions in HepG2 cells. Archives of Biochemistry and Biophysics. 108124. PMID 31585072 DOI: 10.1016/J.Abb.2019.108124 |
0.348 |
|
| 2017 |
Ansari IH, Longacre MJ, Stoker SW, Kendrick MA, O'Neill LM, Zitur LJ, Fernandez LA, Ntambi JM, MacDonald MJ. Characterization of Acyl-CoA synthetase isoforms in pancreatic beta cells: Gene silencing shows participation of ACSL3 and ACSL4 in insulin secretion. Archives of Biochemistry and Biophysics. PMID 28193492 DOI: 10.1016/J.Abb.2017.02.001 |
0.493 |
|
| 2016 |
Phannasil P, Ansari IH, El Azzouny M, Longacre MJ, Rattanapornsompong K, Burant CF, Jitrapakdee S, MacDonald MJ. Mass spectrometry analysis shows the biosynthetic pathways supported by pyruvate carboxylase in highly invasive breast cancer cells. Biochimica Et Biophysica Acta. PMID 27890529 DOI: 10.1016/J.Bbadis.2016.11.021 |
0.314 |
|
| 2016 |
El Azzouny M, Longacre MJ, Ansari IU, Kennedy RT, Burant CF, MacDonald MJ. Knockdown of ATP citrate lyase in pancreatic beta cells does not inhibit insulin secretion or glucose flux and implicates the acetoacetate pathway in insulin secretion. Molecular Metabolism. 5: 980-7. PMID 27689010 DOI: 10.1016/J.Molmet.2016.07.011 |
0.487 |
|
| 2016 |
MacDonald MJ, Hasan NM, Ansari IH, Longacre MJ, Kendrick MA, Stoker SW. Discovery of a Genetic Metabolic Cause for Mauriac Syndrome in Type 1 Diabetes. Diabetes. PMID 27207549 DOI: 10.2337/Db16-0099 |
0.377 |
|
| 2015 |
Ansari IU, Longacre MJ, Paulusma CC, Stoker SW, Kendrick MA, MacDonald MJ. Characterization of P4 ATPase Phospholipid Translocases (Flippases) in Human and Rat Pancreatic Beta Cells: THEIR GENE SILENCING INHIBITS INSULIN SECRETION. The Journal of Biological Chemistry. 290: 23110-23. PMID 26240149 DOI: 10.1074/Jbc.M115.655027 |
0.407 |
|
| 2015 |
MacDonald MJ, Ade L, Ntambi JM, Ansari IU, Stoker SW. Characterization of phospholipids in insulin secretory granules and mitochondria in pancreatic beta cells and their changes with glucose stimulation. The Journal of Biological Chemistry. 290: 11075-92. PMID 25762724 DOI: 10.1074/Jbc.M114.628420 |
0.39 |
|
| 2015 |
Hasan NM, Longacre MJ, Stoker SW, Kendrick MA, MacDonald MJ. Mitochondrial malic enzyme 3 is important for insulin secretion in pancreatic β-cells. Molecular Endocrinology (Baltimore, Md.). 29: 396-410. PMID 25594249 DOI: 10.1210/Me.2014-1249 |
0.483 |
|
| 2014 |
Wutthisathapornchai A, Vongpipatana T, Muangsawat S, Boonsaen T, MacDonald MJ, Jitrapakdee S. Multiple E-boxes in the distal promoter of the rat pyruvate carboxylase gene function as a glucose-responsive element. Plos One. 9: e102730. PMID 25054881 DOI: 10.1371/Journal.Pone.0102730 |
0.387 |
|
| 2014 |
Madiraju AK, Erion DM, Rahimi Y, Zhang XM, Braddock DT, Albright RA, Prigaro BJ, Wood JL, Bhanot S, MacDonald MJ, Jurczak MJ, Camporez JP, Lee HY, Cline GW, Samuel VT, et al. Metformin suppresses gluconeogenesis by inhibiting mitochondrial glycerophosphate dehydrogenase. Nature. 510: 542-6. PMID 24847880 DOI: 10.1038/Nature13270 |
0.412 |
|
| 2014 |
Perez J, MacDonald M. Knockdown of UDP-glucose dehydrogenase in INS-1 832/13 cells inhibits insulin release (767.12) The Faseb Journal. 28. DOI: 10.1096/Fasebj.28.1_Supplement.767.12 |
0.485 |
|
| 2013 |
Wolfgram PM, Macdonald MJ. Severe Hypertriglyceridemia Causing Acute Pancreatitis in a Child with New Onset Type I Diabetes Mellitus Presenting in Ketoacidosis. Journal of Pediatric Intensive Care. 2: 77-80. PMID 24455446 DOI: 10.3233/Pic-13053 |
0.35 |
|
| 2013 |
MacDonald MJ, Brown LJ, Longacre MJ, Stoker SW, Kendrick MA, Hasan NM. Knockdown of both mitochondrial isocitrate dehydrogenase enzymes in pancreatic beta cells inhibits insulin secretion. Biochimica Et Biophysica Acta. 1830: 5104-11. PMID 23876293 DOI: 10.1016/J.Bbagen.2013.07.013 |
0.427 |
|
| 2013 |
MacDonald MJ, Langberg EC, Tibell A, Sabat G, Kendrick MA, Szweda LI, Ostenson CG. Identification of ATP synthase as a lipid peroxide protein adduct in pancreatic islets from humans with and without type 2 diabetes mellitus. The Journal of Clinical Endocrinology and Metabolism. 98: E727-31. PMID 23463654 DOI: 10.1210/Jc.2012-4203 |
0.327 |
|
| 2013 |
Thonpho A, Rojvirat P, Jitrapakdee S, MacDonald MJ. Characterization of the distal promoter of the human pyruvate carboxylase gene in pancreatic beta cells. Plos One. 8: e55139. PMID 23383084 DOI: 10.1371/Journal.Pone.0055139 |
0.344 |
|
| 2013 |
MacDonald MJ, Hasan NM, Dobrzyn A, Stoker SW, Ntambi JM, Liu X, Sampath H. Knockdown of pyruvate carboxylase or fatty acid synthase lowers numerous lipids and glucose-stimulated insulin release in insulinoma cells. Archives of Biochemistry and Biophysics. 532: 23-31. PMID 23357280 DOI: 10.1016/J.Abb.2013.01.002 |
0.471 |
|
| 2013 |
MacDonald MJ, Longacre MJ, Warner TF, Thonpho A. High level of ATP citrate lyase expression in human and rat pancreatic islets. Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et MéTabolisme. 45: 391-3. PMID 23225248 DOI: 10.1055/S-0032-1329987 |
0.411 |
|
| 2013 |
MacDonald MJ, Langberg EC, Tibell A, Sabat G, Kendrick MA, Szweda LI, Ostenson CG. Identification of ATP synthase as a lipid peroxide protein adduct in pancreatic islets from humans with and without type 2 diabetes mellitus (Journal of Clinical Endocrinology and Metabolism (2013) 98, (E727-E731) DOI: 10.1210/jc.2012-4203) Journal of Clinical Endocrinology and Metabolism. 98: 3091. DOI: 10.1210/Jc.2013-2189 |
0.323 |
|
| 2013 |
MacDonald MJ, Brown LJ, Longacre MJ, Stoker SW, Kendrick MA, Hasan NM. Corrigendum to "Knockdown of both mitochondrial isocitrate dehydrogenase enzymes in pancreatic beta cells inhibits insulin secretion" [Biochim. Biophys. Acta Gen. Subj. 1830 (2013) 5104-5111] (DOI:10.1016/j.bbagen.2013.07.013) Biochimica Et Biophysica Acta - General Subjects. DOI: 10.1016/J.Bbagen.2013.09.024 |
0.452 |
|
| 2012 |
Hasan NM, Longacre MJ, Stoker SW, Kendrick MA, Druckenbrod NR, Laychock SG, Mastrandrea LD, MacDonald MJ. Sphingosine kinase 1 knockdown reduces insulin synthesis and secretion in a rat insulinoma cell line. Archives of Biochemistry and Biophysics. 518: 23-30. PMID 22155656 DOI: 10.1016/J.Abb.2011.11.016 |
0.468 |
|
| 2011 |
Fahien LA, Macdonald MJ. The complex mechanism of glutamate dehydrogenase in insulin secretion. Diabetes. 60: 2450-4. PMID 21948999 DOI: 10.2337/Db10-1150 |
0.482 |
|
| 2011 |
MacDonald MJ, Longacre MJ, Stoker SW, Kendrick M, Thonpho A, Brown LJ, Hasan NM, Jitrapakdee S, Fukao T, Hanson MS, Fernandez LA, Odorico J. Differences between human and rodent pancreatic islets: low pyruvate carboxylase, atp citrate lyase, and pyruvate carboxylation and high glucose-stimulated acetoacetate in human pancreatic islets. The Journal of Biological Chemistry. 286: 18383-96. PMID 21454710 DOI: 10.1074/Jbc.M111.241182 |
0.494 |
|
| 2010 |
Hasan NM, Longacre MJ, Seed Ahmed M, Kendrick MA, Gu H, Ostenson CG, Fukao T, MacDonald MJ. Lower succinyl-CoA:3-ketoacid-CoA transferase (SCOT) and ATP citrate lyase in pancreatic islets of a rat model of type 2 diabetes: knockdown of SCOT inhibits insulin release in rat insulinoma cells. Archives of Biochemistry and Biophysics. 499: 62-8. PMID 20460097 DOI: 10.1016/J.Abb.2010.05.007 |
0.513 |
|
| 2010 |
Jitrapakdee S, Wutthisathapornchai A, Wallace JC, MacDonald MJ. Regulation of insulin secretion: role of mitochondrial signalling. Diabetologia. 53: 1019-32. PMID 20225132 DOI: 10.1007/S00125-010-1685-0 |
0.51 |
|
| 2009 |
Brown LJ, Longacre MJ, Hasan NM, Kendrick MA, Stoker SW, Macdonald MJ. Chronic reduction of the cytosolic or mitochondrial NAD(P)-malic enzyme does not affect insulin secretion in a rat insulinoma cell line. The Journal of Biological Chemistry. 284: 35359-67. PMID 19858194 DOI: 10.1074/Jbc.M109.040394 |
0.474 |
|
| 2009 |
MacDonald MJ, Longacre MJ, Kendrick MA. Mitochondrial malic enzyme (ME2) in pancreatic islets of the human, rat and mouse and clonal insulinoma cells. Archives of Biochemistry and Biophysics. 488: 100-4. PMID 19691144 DOI: 10.1016/J.Abb.2009.07.004 |
0.422 |
|
| 2009 |
MacDonald MJ, Longacre MJ, Langberg EC, Tibell A, Kendrick MA, Fukao T, Ostenson CG. Decreased levels of metabolic enzymes in pancreatic islets of patients with type 2 diabetes. Diabetologia. 52: 1087-91. PMID 19296078 DOI: 10.1007/S00125-009-1319-6 |
0.432 |
|
| 2008 |
Hasan NM, Longacre MJ, Stoker SW, Boonsaen T, Jitrapakdee S, Kendrick MA, Wallace JC, MacDonald MJ. Impaired anaplerosis and insulin secretion in insulinoma cells caused by small interfering RNA-mediated suppression of pyruvate carboxylase. The Journal of Biological Chemistry. 283: 28048-59. PMID 18697738 DOI: 10.1074/Jbc.M804170200 |
0.503 |
|
| 2008 |
Fallon MJ, MacDonald MJ. Beta-cell alpha-ketoglutarate hydroxylases may acutely participate in insulin secretion. Metabolism: Clinical and Experimental. 57: 1148-54. PMID 18640395 DOI: 10.1016/J.Metabol.2008.03.022 |
0.462 |
|
| 2008 |
Macdonald MJ, Hasan NM, Longacre MJ. Studies with leucine, beta-hydroxybutyrate and ATP citrate lyase-deficient beta cells support the acetoacetate pathway of insulin secretion. Biochimica Et Biophysica Acta. 1780: 966-72. PMID 18439432 DOI: 10.1016/J.Bbagen.2008.03.017 |
0.482 |
|
| 2008 |
MacDonald MJ, Stoker SW, Hasan NM. Anaplerosis from glucose, alpha-ketoisocaproate, and pyruvate in pancreatic islets, INS-1 cells and liver mitochondria. Molecular and Cellular Biochemistry. 313: 195-202. PMID 18414997 DOI: 10.1007/S11010-008-9757-X |
0.428 |
|
| 2008 |
Edghill EL, Flanagan SE, Patch AM, Boustred C, Parrish A, Shields B, Shepherd MH, Hussain K, Kapoor RR, Malecki M, MacDonald MJ, Støy J, Steiner DF, Philipson LH, Bell GI, et al. Insulin mutation screening in 1,044 patients with diabetes: mutations in the INS gene are a common cause of neonatal diabetes but a rare cause of diabetes diagnosed in childhood or adulthood. Diabetes. 57: 1034-42. PMID 18162506 DOI: 10.2337/Db07-1405 |
0.313 |
|
| 2008 |
MacDonald MJ, Longacre MJ, Stoker SW, Brown LJ, Hasan NM, Kendrick MA. Acetoacetate and beta-hydroxybutyrate in combination with other metabolites release insulin from INS-1 cells and provide clues about pathways in insulin secretion. American Journal of Physiology. Cell Physiology. 294: C442-50. PMID 18160486 DOI: 10.1152/Ajpcell.00368.2007 |
0.474 |
|
| 2008 |
MacDonald MJ, Dobrzyn A, Ntambi J, Stoker SW. The role of rapid lipogenesis in insulin secretion: Insulin secretagogues acutely alter lipid composition of INS-1 832/13 cells. Archives of Biochemistry and Biophysics. 470: 153-62. PMID 18082128 DOI: 10.1016/J.Abb.2007.11.017 |
0.474 |
|
| 2007 |
MacDonald MJ, Smith AD, Hasan NM, Sabat G, Fahien LA. Feasibility of pathways for transfer of acyl groups from mitochondria to the cytosol to form short chain acyl-CoAs in the pancreatic beta cell. The Journal of Biological Chemistry. 282: 30596-606. PMID 17724028 DOI: 10.1074/Jbc.M702732200 |
0.489 |
|
| 2007 |
McVean JJ, Eickhoff JC, MacDonald MJ. Factors correlating with improved A1C in children using continuous subcutaneous insulin infusion. Diabetes Care. 30: 2499-500. PMID 17586738 DOI: 10.2337/Dc07-0614 |
0.318 |
|
| 2007 |
MacDonald MJ. Synergistic potent insulin release by combinations of weak secretagogues in pancreatic islets and INS-1 cells. The Journal of Biological Chemistry. 282: 6043-52. PMID 17210580 DOI: 10.1074/Jbc.M606652200 |
0.493 |
|
| 2006 |
MacDonald MJ, Chaplen FW, Triplett CK, Gong Q, Drought H. Stimulation of insulin release by glyceraldehyde may not be similar to glucose. Archives of Biochemistry and Biophysics. 447: 118-26. PMID 16530160 DOI: 10.1016/J.Abb.2006.01.019 |
0.396 |
|
| 2005 |
MacDonald MJ, Fahien LA, Brown LJ, Hasan NM, Buss JD, Kendrick MA. Perspective: emerging evidence for signaling roles of mitochondrial anaplerotic products in insulin secretion. American Journal of Physiology. Endocrinology and Metabolism. 288: E1-15. PMID 15585595 DOI: 10.1152/Ajpendo.00218.2004 |
0.46 |
|
| 2004 |
Gunawardana SC, Liu YJ, Macdonald MJ, Straub SG, Sharp GW. Anaplerotic input is sufficient to induce time-dependent potentiation of insulin release in rat pancreatic islets. American Journal of Physiology. Endocrinology and Metabolism. 287: E828-33. PMID 15475511 DOI: 10.1152/Ajpendo.00381.2003 |
0.389 |
|
| 2004 |
MacDonald MJ. Production and export of metabolites from liver and heart mitochondria and anaplerosis. Molecular and Cellular Biochemistry. 258: 201-10. PMID 15030185 DOI: 10.1023/B:Mcbi.0000012856.31929.91 |
0.314 |
|
| 2003 |
MacDonald MJ, Fahien LA, Buss JD, Hasan NM, Fallon MJ, Kendrick MA. Citrate oscillates in liver and pancreatic beta cell mitochondria and in INS-1 insulinoma cells. The Journal of Biological Chemistry. 278: 51894-900. PMID 14522964 DOI: 10.1074/Jbc.M309038200 |
0.384 |
|
| 2003 |
Macdonald MJ. Export of metabolites from pancreatic islet mitochondria as a means to study anaplerosis in insulin secretion. Metabolism: Clinical and Experimental. 52: 993-8. PMID 12898463 DOI: 10.1016/S0026-0495(03)00149-5 |
0.498 |
|
| 2003 |
Liu YJ, Cheng H, Drought H, MacDonald MJ, Sharp GW, Straub SG. Activation of the KATP channel-independent signaling pathway by the nonhydrolyzable analog of leucine, BCH. American Journal of Physiology. Endocrinology and Metabolism. 285: E380-9. PMID 12709398 DOI: 10.1152/Ajpendo.00008.2003 |
0.426 |
|
| 2003 |
MacDonald MJ. The export of metabolites from mitochondria and anaplerosis in insulin secretion. Biochimica Et Biophysica Acta. 1619: 77-88. PMID 12495818 DOI: 10.1016/S0304-4165(02)00443-9 |
0.471 |
|
| 2002 |
Hasan NM, MacDonald MJ. Sp/Krüppel-like transcription factors are essential for the expression of mitochondrial glycerol phosphate dehydrogenase promoter B. Gene. 296: 221-34. PMID 12383520 DOI: 10.1016/S0378-1119(02)00865-X |
0.313 |
|
| 2002 |
Fahien LA, MacDonald MJ. The succinate mechanism of insulin release. Diabetes. 51: 2669-76. PMID 12196457 DOI: 10.2337/Diabetes.51.9.2669 |
0.399 |
|
| 2002 |
MacDonald MJ. Differences between mouse and rat pancreatic islets: succinate responsiveness, malic enzyme, and anaplerosis. American Journal of Physiology. Endocrinology and Metabolism. 283: E302-10. PMID 12110535 DOI: 10.1152/Ajpendo.00041.2002 |
0.434 |
|
| 2002 |
MacDonald MJ, Kelley PC, Laclau M. Histochemical evidence for pathways insulin cells use to oxidize glycolysis-derived NADH. Metabolism: Clinical and Experimental. 51: 318-21. PMID 11887167 DOI: 10.1053/Meta.2002.29960 |
0.495 |
|
| 2001 |
Laclau M, Lu F, MacDonald MJ. Enzymes in pancreatic islets that use NADP(H) as a cofactor including evidence for a plasma membrane aldehyde reductase. Molecular and Cellular Biochemistry. 225: 151-60. PMID 11716357 DOI: 10.1023/A:1012238709063 |
0.475 |
|
| 2001 |
MacDonald MJ, Marshall LK. Survey of normal appearing mouse strain which lacks malic enzyme and Nad+-linked glycerol phosphate dehydrogenase: normal pancreatic beta cell function, but abnormal metabolite pattern in skeletal muscle. Molecular and Cellular Biochemistry. 220: 117-25. PMID 11451371 DOI: 10.1023/A:1010821821921 |
0.424 |
|
| 2000 |
MacDonald MJ, Marshall LK. Mouse lacking NAD+-linked glycerol phosphate dehydrogenase has normal pancreatic beta cell function but abnormal metabolite pattern in skeletal muscle. Archives of Biochemistry and Biophysics. 384: 143-53. PMID 11147825 DOI: 10.1006/Abbi.2000.2107 |
0.443 |
|
| 2000 |
MacDonald MJ, Fahien LA. Glutamate is not a messenger in insulin secretion. The Journal of Biological Chemistry. 275: 34025-7. PMID 10967090 DOI: 10.1074/Jbc.C000411200 |
0.451 |
|
| 2000 |
Clifford KS, MacDonald MJ. Survey of mRNAs encoding zinc transporters and other metal complexing proteins in pancreatic islets of rats from birth to adulthood: similar patterns in the Sprague-Dawley and Wistar BB strains. Diabetes Research and Clinical Practice. 49: 77-85. PMID 10963817 DOI: 10.1016/S0168-8227(00)00141-8 |
0.35 |
|
| 2000 |
Gong Q, Brown LJ, MacDonald MJ. Functional analysis of two promoters for the human mitochondrial glycerol phosphate dehydrogenase gene. The Journal of Biological Chemistry. 275: 38012-21. PMID 10954707 DOI: 10.1074/Jbc.M004078200 |
0.4 |
|
| 1999 |
Jitrapakdee S, Gong Q, MacDonald MJ, Wallace JC. Regulation of rat pyruvate carboxylase gene expression by alternate promoters during development, in genetically obese rats and in insulin-secreting cells. Multiple transcripts with 5'-end heterogeneity modulate translation. The Journal of Biological Chemistry. 273: 34422-8. PMID 9852109 DOI: 10.1074/Jbc.273.51.34422 |
0.345 |
|
| 1997 |
MacDonald MJ, Al-Masri H, Jumelle-Laclau M, Cruz MO. Oscillations in activities of enzymes in pancreatic islet subcellular fractions induced by physiological concentrations of effectors Diabetes. 46: 1996-2001. PMID 9392486 DOI: 10.2337/Diab.46.12.1996 |
0.45 |
|
| 1997 |
MacDonald MJ, Brown LJ, Hasan NM, Stoffel M, Dills DG. Single-stranded conformational polymorphism analysis of the mitochondrial glycerol phosphate dehydrogenase gene in NIDDM. Diabetes. 46: 1660-1. PMID 9313767 DOI: 10.2337/Diacare.46.10.1660 |
0.35 |
|
| 1997 |
MacDonald MJ. Glucose-stimulated expressed sequence tags from rat pancreatic islets. Molecular and Cellular Endocrinology. 123: 199-204. PMID 8961257 DOI: 10.1016/S0303-7207(96)03918-4 |
0.459 |
|
| 1997 |
Koike G, Van Vooren P, Shiozawa M, Galli J, Li LS, Glaser A, Balasubramanyam A, Brown LJ, Luthman H, Szpirer C, MacDonald MJ, Jacob HJ. Genetic mapping and chromosome localization of the rat mitochondrial glycerol-3-phosphate dehydrogenase gene, a candidate for non-insulin-dependent diabetes mellitus. Genomics. 38: 96-9. PMID 8954787 DOI: 10.1006/Geno.1996.0599 |
0.379 |
|
| 1997 |
Koza RA, Kozak UC, Brown LJ, Leiter EH, MacDonald MJ, Kozak LP. Sequence and tissue-dependent RNA expression of mouse FAD-linked glycerol-3-phosphate dehydrogenase. Archives of Biochemistry and Biophysics. 336: 97-104. PMID 8951039 DOI: 10.1006/Abbi.1996.0536 |
0.309 |
|
| 1996 |
MacDonald MJ, Tang J, Polonsky KS. Low mitochondrial glycerol phosphate dehydrogenase and pyruvate carboxylase in pancreatic islets of Zucker diabetic fatty rats. Diabetes. 45: 1626-30. PMID 8866570 DOI: 10.2337/Diab.45.11.1626 |
0.423 |
|
| 1996 |
Simonson GD, Groskreutz DJ, Gorman CM, MacDonald MJ. Synthesis and processing of genetically modified human proinsulin by rat myoblast primary cultures Human Gene Therapy. 7: 71-78. PMID 8825870 DOI: 10.1089/Hum.1996.7.1-71 |
0.432 |
|
| 1996 |
Brown LJ, Stoffel M, Moran SM, Fernald AA, Lehn DA, LeBeau MM, MacDonald MJ. Structural organization and mapping of the human mitochondrial glycerol phosphate dehydrogenase-encoding gene and pseudogene. Gene. 172: 309-12. PMID 8682323 DOI: 10.1016/0378-1119(96)00019-4 |
0.334 |
|
| 1996 |
MacDonald MJ, Efendić S, Ostenson CG. Normalization by insulin treatment of low mitochondrial glycerol phosphate dehydrogenase and pyruvate carboxylase in pancreatic islets of the GK rat. Diabetes. 45: 886-90. PMID 8666138 DOI: 10.2337/Diab.45.7.886 |
0.477 |
|
| 1996 |
Warren-Perry MG, Stoffel M, Saker PJ, Zhang Y, Brown LJ, MacDonald MJ, Turner RC. Mitochondrial FAD-glycerophosphate dehydrogenase and G-protein-coupled inwardly rectifying K+ channel: No evidence for linkage in maturity-onset diabetes of the young or NIDDM. Diabetes. 45: 639-41. PMID 8621016 DOI: 10.2337/Diab.45.5.639 |
0.352 |
|
| 1996 |
Kerouz N, el-Hayek R, Langhough R, MacDonald MJ. Insulin doses in children using conventional therapy for insulin dependent diabetes. Diabetes Research and Clinical Practice. 29: 113-20. PMID 8591698 DOI: 10.1016/0168-8227(95)01122-6 |
0.391 |
|
| 1996 |
MacDonald MJ, Brown LJ. Calcium activation of mitochondrial glycerol phosphate dehydrogenase restudied Archives of Biochemistry and Biophysics. 326: 79-84. PMID 8579375 DOI: 10.1006/Abbi.1996.0049 |
0.381 |
|
| 1995 |
MacDonald MJ, Moran SM, Simonson GD. The amino acid sequence of the pancreatic islet mitochondrial glycerol phosphate dehydrogenase is not unique and the enzyme is not thyroid or glucose responsive Archives of Biochemistry and Biophysics. 319: 305-308. PMID 7771800 DOI: 10.1006/abbi.1995.1297 |
0.353 |
|
| 1995 |
MacDonald MJ. Influence of glucose on pyruvate carboxylase expression in pancreatic islets. Archives of Biochemistry and Biophysics. 319: 128-32. PMID 7771776 DOI: 10.1006/abbi.1995.1274 |
0.394 |
|
| 1995 |
MacDonald MJ. Is liver type pyruvate kinase present in the normal pancreatic islet? Diabetologia. 38: 125. PMID 7744221 DOI: 10.1007/Bf02369367 |
0.335 |
|
| 1995 |
MacDonald MJ. Feasibility of a mitochondrial pyruvate malate shuttle in pancreatic islets. Further implication of cytosolic NADPH in insulin secretion. The Journal of Biological Chemistry. 270: 20051-8. PMID 7650022 DOI: 10.1074/Jbc.270.34.20051 |
0.46 |
|
| 1994 |
MacDonald MJ, Shahidi NT, Allen DB, Lustig RH, Mitchell TL, Cornwell ST. Pentoxifylline in the treatment of children with new-onset type I diabetes mellitus. Jama. 271: 27-8. PMID 8258882 DOI: 10.1001/Jama.1994.03510250043028 |
0.401 |
|
| 1994 |
MacDonald MJ, Cook JD, Epstein ML, Flowers CH. Large amount of (Apo)ferritin in the pancreatic insulin cell and its stimulation by glucose Faseb Journal. 8: 777-781. PMID 8050678 DOI: 10.1096/fasebj.8.10.8050678 |
0.354 |
|
| 1993 |
MacDonald MJ. Metabolism of the insulin secretagogue methyl succinate by pancreatic islets. Archives of Biochemistry and Biophysics. 300: 201-5. PMID 8424653 DOI: 10.1006/abbi.1993.1028 |
0.344 |
|
| 1993 |
MacDonald MJ. Glucose enters mitochondrial metabolism via both carboxylation and decarboxylation of pyruvate in pancreatic islets. Metabolism: Clinical and Experimental. 42: 1229-31. PMID 8412734 DOI: 10.1016/0026-0495(93)90118-8 |
0.459 |
|
| 1993 |
MacDonald MJ. Estimates of glycolysis, pyruvate (de)carboxylation, pentose phosphate pathway, and methyl succinate metabolism in incapacitated pancreatic islets. Archives of Biochemistry and Biophysics. 305: 205-14. PMID 8373157 DOI: 10.1006/abbi.1993.1413 |
0.317 |
|
| 1992 |
Allen DB, Cornwell ST, Liston LA, Carlson IH, MacDonald MJ. Correlation of glycosylated hemoglobin measured by affinity vs ion exchange chromatography with mean blood sugar in pediatric IDDM patients. Diabetes Research and Clinical Practice. 14: 75-81. PMID 1748065 DOI: 10.1016/0168-8227(91)90055-I |
0.318 |
|
| 1992 |
MacDonald MJ, McKenzie DI, Walker TM, Kaysen JH. Lack of glyconeogenesis in pancreatic islets: expression of gluconeogenic enzyme genes in islets. Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et MéTabolisme. 24: 158-60. PMID 1601389 DOI: 10.1055/S-2007-1003284 |
0.498 |
|
| 1991 |
MacDonald MJ. Elusive proximal signals of beta-cells for insulin secretion. Diabetes. 39: 1461-6. PMID 2245873 DOI: 10.2337/Diab.39.12.1461 |
0.473 |
|
| 1991 |
MacDonald MJ, McKenzie DI, Kaysen JH, Walker TM, Moran SM, Fahien LA, Towle HC. Glucose regulates leucine-induced insulin release and the expression of the branched chain ketoacid dehydrogenase E1 alpha subunit gene in pancreatic islets. The Journal of Biological Chemistry. 266: 1335-40. PMID 1985951 |
0.379 |
|
| 1991 |
MacDonald MJ, Kaysen JH, Moran SM, Pomije CE. Pyruvate dehydrogenase and pyruvate carboxylase: Sites of pretranslational regulation by glucose of glucose-induced insulin release in pancreatic islets Journal of Biological Chemistry. 266: 22392-22397. PMID 1939263 |
0.361 |
|
| 1991 |
MacDonald MJ. Quinone reductase enzyme activity in pancreatic islets. Endocrinology. 129: 1370-4. PMID 1874176 DOI: 10.1210/Endo-129-3-1370 |
0.48 |
|
| 1991 |
MacDonald MJ. Stimulation of insulin release from pancreatic islets by quinones. Bioscience Reports. 11: 165-70. PMID 1720333 DOI: 10.1007/Bf01182485 |
0.481 |
|
| 1990 |
MacDonald MJ, Fahien LA, McKenzie DI, Moran SM. Novel effects of insulin secretagogues on capacitation of insulin release and survival of cultured pancreatic islets American Journal of Physiology - Endocrinology and Metabolism. 259. PMID 2221056 DOI: 10.1152/Ajpendo.1990.259.4.E548 |
0.463 |
|
| 1990 |
MacDonald MJ, Fahien LA. Insulin release in pancreatic islets by a glycolytic and a Krebs cycle intermediate: contrasting patterns of glyceraldehyde phosphate and succinate. Archives of Biochemistry and Biophysics. 279: 104-8. PMID 2186702 DOI: 10.1016/0003-9861(90)90468-E |
0.49 |
|
| 1989 |
MacDonald MJ, Gapinski JP. A rapid ELISA for measuring insulin in a large number of research samples. Metabolism: Clinical and Experimental. 38: 450-2. PMID 2657325 DOI: 10.1016/0026-0495(89)90197-2 |
0.439 |
|
| 1989 |
MacDonald MJ, Fahien LA, Mertz RJ, Rana RS. Effect of esters of succinic acid and other citric acid cycle intermediates on insulin release and inositol phosphate formation by pancreatic islets Archives of Biochemistry and Biophysics. 269: 400-406. PMID 2645827 DOI: 10.1016/0003-9861(89)90123-9 |
0.489 |
|
| 1989 |
MacDonald MJ, Mertz RJ, Rana RS. Glyceraldehyde phosphate: An insulin secretagogue with possible effects on inositol phosphate formation in pancreatic islets Archives of Biochemistry and Biophysics. 269: 194-200. PMID 2644893 DOI: 10.1016/0003-9861(89)90100-8 |
0.493 |
|
| 1989 |
MacDonald MJ. Does glyceraldehyde enter pancreatic islet metabolism via both the triokinase and the glyceraldehyde phosphate dehydrogenase reactions? A study of these enzymes in islets. Archives of Biochemistry and Biophysics. 270: 15-22. PMID 2539042 |
0.431 |
|
| 1988 |
MacDonald MJ. Postexercise late-onset hypoglycemia in insulin-dependent diabetic patients. Diabetes Care. 10: 584-8. PMID 3677976 DOI: 10.2337/Diacare.10.5.584 |
0.35 |
|
| 1988 |
MacDonald MJ, Fahien LA. Glyceraldehyde phosphate and methyl esters of succinic acid. Two "new" potent insulin secretagogues. Diabetes. 37: 997-9. PMID 3290012 DOI: 10.2337/Diab.37.7.997 |
0.476 |
|
| 1988 |
Fahien LA, MacDonald MJ, Kmiotek EH, Mertz RJ, Fahien CM. Regulation of insulin release by factors that also modify glutamate dehydrogenase Journal of Biological Chemistry. 263: 13610-13614. PMID 3047128 |
0.306 |
|
| 1987 |
MacDonald MJ, Liston L, Carlson I. Seasonality in glycosylated hemoglobin in normal subjects. Does seasonal incidence in insulin-dependent diabetes suggest specific etiology? Diabetes. 36: 265-8. PMID 3803736 DOI: 10.2337/Diab.36.3.265 |
0.435 |
|
| 1986 |
Rana RS, Kowluru A, MacDonald MJ. Secretagogue-responsive and -unresponsive pools of phosphatidylinositol in pancreatic islets. Archives of Biochemistry and Biophysics. 245: 411-6. PMID 3513707 DOI: 10.1016/0003-9861(86)90232-8 |
0.621 |
|
| 1986 |
Rana RS, Kowluru A, MacDonald MJ. Enzymes of phospholipid metabolism in rat pancreatic islets: subcellular distribution and the effect of glucose and calcium. Journal of Cellular Biochemistry. 32: 143-50. PMID 3023405 DOI: 10.1002/Jcb.240320206 |
0.682 |
|
| 1986 |
MACDONALD MJ, GOTTISCHALL J, HUNTER JB, WINTER KL, JOHNSON SD, BLANK JL, MASON EP, MABY S. In Insulin-Dependent Diabetes, the Expression of an HLA-DR4-Related Susceptibility Gene Is Dominant, but Expression of a DR3-Related Gene Is Dependent on the DR4-Related Gene Annals of the New York Academy of Sciences. 475: 356-358. DOI: 10.1111/J.1749-6632.1986.Tb20892.X |
0.308 |
|
| 1985 |
Rana RS, Mertz RJ, Kowluru A, Dixon JF, Hokin LE, MacDonald MJ. Evidence for glucose-responsive and -unresponsive pools of phospholipid in pancreatic islets Journal of Biological Chemistry. 260: 7861-7867. PMID 3924909 |
0.631 |
|
| 1985 |
MacDonald MJ, Chang CM. Pancreatic islets contain the M2 isoenzyme of pyruvate kinase its phosphorylation has no effect on enzyme activity Molecular and Cellular Biochemistry. 68: 115-120. PMID 3908905 DOI: 10.1007/Bf00219375 |
0.347 |
|
| 1985 |
MacDonald MJ, Kowluru A, Chang CM. Evidence for phosphorylation of pancreatic islet pyruvate kinase. Metabolism: Clinical and Experimental. 34: 600-3. PMID 3892225 DOI: 10.1016/0026-0495(85)90084-8 |
0.62 |
|
| 1985 |
MacDonald MJ, Chang CM. Do pancreatic islets contain significant amounts of phosphoenolpyruvate carboxykinase or ferroactivator activity? Diabetes. 34: 246-250. PMID 3882492 DOI: 10.2337/Diab.34.3.246 |
0.405 |
|
| 1985 |
MacDonald MJ, Chang CM, Kowluru A. Activation of pancreatic islet myosin ATPase by ATP and actin. Biochemical Medicine. 33: 362-6. PMID 3160344 DOI: 10.1016/0006-2944(85)90011-0 |
0.652 |
|
| 1985 |
MacDonald MJ, Kowluru A. Evidence for calcium enhanced phosphorylation of pyruvate kinase by pancreatic islets. Molecular and Cellular Biochemistry. 68: 107-14. PMID 3001500 DOI: 10.1007/Bf00219374 |
0.587 |
|
| 1985 |
Kowluru A, Rana RS, MacDonald MJ. Phospholipid methyltransferase activity in pancreatic islets: activation by calcium. Archives of Biochemistry and Biophysics. 242: 72-81. PMID 2996436 DOI: 10.1016/0003-9861(85)90481-3 |
0.639 |
|
| 1984 |
Kowluru A, Rana RS, MacDonald MJ. Stimulation of phospholipid methylation by glucose in pancreatic islets. Biochemical and Biophysical Research Communications. 122: 706-11. PMID 6380500 DOI: 10.1016/S0006-291X(84)80091-1 |
0.646 |
|
| 1984 |
Kowluru A, MacDonald MJ. Glucose-induced, calcium-mediated protein phosphorylation in intact pancreatic islets. Archives of Biochemistry and Biophysics. 231: 320-7. PMID 6375571 DOI: 10.1016/0003-9861(84)90394-1 |
0.669 |
|
| 1984 |
Kowluru A, MacDonald MJ. Protein phosphorylation in pancreatic islets: evidence for separate Ca2+ and cAMP-enhanced phosphorylation of two 57,000 Mr proteins. Biochemical and Biophysical Research Communications. 118: 797-804. PMID 6322766 DOI: 10.1016/0006-291X(84)91465-7 |
0.602 |
|
| 1983 |
MacDonald MJ, Warner TF, Pellett JR. Increased mitochondrial glycerol phosphate dehydrogenase activity in insulinomas of two hypoglycemic infants. The Journal of Clinical Endocrinology and Metabolism. 57: 662-4. PMID 6308035 DOI: 10.1210/Jcem-57-3-662 |
0.473 |
|
| 1982 |
MacDonald MJ, Kowluru A. Calcium-activated factors in pancreatic islets that inhibit actin polymerization. Archives of Biochemistry and Biophysics. 219: 459-62. PMID 6762149 DOI: 10.1016/0003-9861(82)90178-3 |
0.632 |
|
| 1982 |
MacDonald MJ. Evidence for the malate aspartate shuttle in pancreatic islets. Archives of Biochemistry and Biophysics. 213: 643-9. PMID 6462111 DOI: 10.1016/0003-9861(82)90594-X |
0.474 |
|
| 1982 |
MacDonald MJ, Kowluru A. Calcium-calmodulin-dependent myosin phosphorylation by pancreatic islets. Diabetes. 31: 566-70. PMID 6295860 DOI: 10.2337/Diab.31.6.566 |
0.637 |
|
| 1981 |
MacDonald MJ. Rapid inactivation of rat liver phosphoenolpyruvate carboxykinase by microsomes and reversal by reductants. Biochimica Et Biophysica Acta. 615: 223-36. PMID 7426661 DOI: 10.1016/0005-2744(80)90025-X |
0.328 |
|
| 1981 |
MacDonald MJ, Grewe BK. Inhibition of phosphoenolpyruvate carboxykinase, glyceroneogenesis and fatty acid synthesis in rat adipose tissue by quinolinate and 3-mercaptopicolinate. Biochimica Et Biophysica Acta. 663: 302-13. PMID 7213768 DOI: 10.1016/0005-2760(81)90216-2 |
0.317 |
|
| 1981 |
MacDonald MJ. Flavin content of intracellular compartments of pancreatic islets compared with acinar tissue and liver. Endocrinology. 108: 1899-902. PMID 7011788 DOI: 10.1210/Endo-108-5-1899 |
0.351 |
|
| 1981 |
MacDonald MJ. Inexpensive modification of a Polytron for rapid mincing of pancreases for islet isolation. Analytical Biochemistry. 108: 419-21. PMID 7006456 DOI: 10.1016/0003-2697(80)90607-7 |
0.311 |
|
| 1978 |
MacDonald MJ, Huang MT, Lardy HA. Hyperglycaemic activity and metabolic effects of 3-aminopicolinic acid. The Biochemical Journal. 176: 495-504. PMID 743255 DOI: 10.1042/Bj1760495 |
0.423 |
|
| 1978 |
MacDonald MJ, Lardy HA. Structural requirements for pyridine carboxylate effects on phosphoenolpyruvate carboxykinase Bioorganic Chemistry. 7: 251-262. DOI: 10.1016/0045-2068(78)90053-6 |
0.308 |
|
| 1975 |
MacDonald MJ, Ball DH, Patel TN, Lauris V, Steinke J. Studies of insulin release and rat pancreatic islet metabolism with diastereomers of D-glucose. Biochimica Et Biophysica Acta. 385: 188-93. PMID 1092356 |
0.372 |
|
| 1974 |
MacDonald MJ, Ammon HP, Patel T, Steinke J. Failure of 6-aminonicotinamide to inhibit the potentiating effect of leucine and arginine on glucose-induced insulin release in vitrol. Diabetologia. 10: 761-5. PMID 4280366 |
0.323 |
|
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