Louis H. Philipson - Publications

Affiliations: 
University of Chicago, Chicago, IL 
Area:
Molecular Biology, Neuroscience Biology, General Biophysics

150 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Haliyur R, Walker JT, Sanyoura M, Reihsmann CV, Shrestha S, Aramandla R, Poffenberger G, Ramirez AH, Redick SD, Babon JAB, Prasad N, Hegele RA, Kent SC, Harlan DM, Bottino R, ... Philipson LH, et al. Integrated Analysis of the Pancreas and Islets Reveals Unexpected Findings in Human Male With Type 1 Diabetes. Journal of the Endocrine Society. 5: bvab162. PMID 34870058 DOI: 10.1210/jendso/bvab162  0.304
2020 Herold KC, Reynolds J, Dziura J, Baidal D, Gaglia J, Gitelman SE, Gottlieb PA, Marks J, Philipson LH, Pop-Busui R, Weinstock RS. Exenatide ER in patients with Type 1 diabetes with and without residual insulin production. Diabetes, Obesity & Metabolism. PMID 32573927 DOI: 10.1111/Dom.14121  0.382
2020 Chung WK, Erion K, Florez JC, Hattersley AT, Hivert MF, Lee CG, McCarthy MI, Nolan JJ, Norris JM, Pearson ER, Philipson L, McElvaine AT, Cefalu WT, Rich SS, Franks PW. Precision Medicine in Diabetes: A Consensus Report From the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD). Diabetes Care. 43: 1617-1635. PMID 32561617 DOI: 10.2337/Dci20-0022  0.363
2020 Chung WK, Erion K, Florez JC, Hattersley AT, Hivert MF, Lee CG, McCarthy MI, Nolan JJ, Norris JM, Pearson ER, Philipson L, McElvaine AT, Cefalu WT, Rich SS, Franks PW. Precision medicine in diabetes: a Consensus Report from the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD). Diabetologia. PMID 32556613 DOI: 10.1007/S00125-020-05181-W  0.363
2020 Pratley RE, Kanapka LG, Rickels MR, Ahmann A, Aleppo G, Beck R, Bhargava A, Bode BW, Carlson A, Chaytor NS, Fox DS, Goland R, Hirsch IB, Kruger D, Kudva YC, ... ... Philipson L, et al. Effect of Continuous Glucose Monitoring on Hypoglycemia in Older Adults With Type 1 Diabetes: A Randomized Clinical Trial. Jama. 323: 2397-2406. PMID 32543682 DOI: 10.1001/Jama.2020.6928  0.348
2020 Philipson LH. Harnessing heterogeneity in type 2 diabetes mellitus. Nature Reviews Endocrinology. 16: 79-80. PMID 31831872 DOI: 10.1038/S41574-019-0308-1  0.335
2020 Harris A, Naylor RN, Sanyoura M, Greeley SAW, Kandasamy B, Philipson LH, Letourneau-Freiberg LR. 178-LB: Insights from the University of Chicago Monogenic Diabetes Registry on Diagnosis and Management of Monogenic Diabetes Diabetes. 69. DOI: 10.2337/Db20-178-Lb  0.357
2020 Zhang H, Maloney KA, Barbetti F, Greeley SAW, Kettunen JLT, Miranda JP, Mirshahi UL, Molnes J, Murphy R, Naylor RN, Pakyz RE, Philipson LH, Prudente S, Tuomi T, Udler M, et al. 1453-P: Adaption of the ACMG/AMP Variant Interpretation Guidelines for GCK, HNF1A, HNF4A-MODY: Recommendations from the ClinGen Monogenic Diabetes Expert Panel Diabetes. 69. DOI: 10.2337/Db20-1453-P  0.347
2020 Virostko J, Williams JM, Hilmes MA, Du L, Kang H, Russell WE, Triolo TM, Philipson LH, Sims EK, Evans-Molina C, Thomas HE, Kay T, Greeley SAW, Steck A, Powers AC, et al. 1283-P: Multicenter Assessment of the Pancreas in Type 1 Diabetes (MAP-T1D) Diabetes. 69. DOI: 10.2337/Db20-1283-P  0.326
2020 Herold KC, Reynolds J, Dziura J, Baidal D, Gaglia J, Gitelman SE, Gottlieb PA, Marks J, Philipson LH, Pop‐Busui R, Weinstock RS. Author response for "Exenatide ER in patients with Type 1 diabetes with and without residual insulin production" Diabetes, Obesity and Metabolism. DOI: 10.1111/Dom.14121/V2/Response1  0.382
2019 Gregory JM, Smith TJ, Slaughter JC, Mason HR, Hughey CC, Smith MS, Kandasamy B, Greeley SAW, Philipson LH, Naylor RN, Letourneau LR, Abumrad NN, Cherrington AD, Moore DJ. Iatrogenic Hyperinsulinemia, Not Hyperglycemia, Drives Insulin Resistance in Type 1 Diabetes as Revealed by Comparison to GCK-MODY (MODY2). Diabetes. PMID 31092478 DOI: 10.2337/Db19-0324  0.412
2019 Sanyoura M, Letourneau L, Knight Johnson AE, Del Gaudio D, Greeley SAW, Philipson LH, Naylor RN. GCK-MODY in the US Monogenic Diabetes Registry: Description of 27 unpublished variants. Diabetes Research and Clinical Practice. 151: 231-236. PMID 31063852 DOI: 10.1016/J.Diabres.2019.04.017  0.328
2019 McCauley M, Letourneau L, Harris A, Philipson L, Naylor R, Greeley SA. SAT-129 Examining the Role of Genetic Testing in Early Onset Diabetes Occurring After 6 Months of Age Journal of the Endocrine Society. 3. DOI: 10.1210/Js.2019-Sat-129  0.315
2018 Haliyur R, Tong X, Sanyoura M, Shrestha S, Lindner J, Saunders DC, Aramandla R, Poffenberger G, Redick SD, Bottino R, Prasad N, Levy SE, Blind RD, Harlan DM, Philipson LH, et al. Human islets expressing HNF1A variant have defective β cell transcriptional regulatory networks. The Journal of Clinical Investigation. PMID 30507613 DOI: 10.1172/Jci121994  0.437
2018 Feng J, Hajizadeh I, Yu X, Rashid M, Turksoy K, Samadi S, Sevil M, Hobbs N, Brandt R, Lazaro C, Maloney Z, Littlejohn E, Philipson LH, Cinar A. Multi-level Supervision and Modification of Artificial Pancreas Control System. Computers & Chemical Engineering. 112: 57-69. PMID 30287976 DOI: 10.1016/J.Compchemeng.2018.02.002  0.305
2018 Sanyoura M, Philipson LH, Naylor R. Monogenic Diabetes in Children and Adolescents: Recognition and Treatment Options. Current Diabetes Reports. 18: 58-58. PMID 29931562 DOI: 10.1007/S11892-018-1024-2  0.379
2018 Greeley SAW, Letourneau LR, Philipson LH. Precision medicine in KCNJ11 permanent neonatal diabetes. The Lancet. Diabetes & Endocrinology. PMID 29880307 DOI: 10.1016/S2213-8587(18)30138-4  0.345
2018 Brissova M, Haliyur R, Saunders D, Shrestha S, Dai C, Blodgett DM, Bottino R, Campbell-Thompson M, Aramandla R, Poffenberger G, Lindner J, Pan FC, von Herrath MG, Greiner DL, Shultz LD, ... ... Philipson LH, et al. α Cell Function and Gene Expression Are Compromised in Type 1 Diabetes. Cell Reports. 22: 2667-2676. PMID 29514095 DOI: 10.1016/J.Celrep.2018.02.032  0.367
2018 Letourneau LR, Carmody D, Philipson LH, Greeley SAW. Early Intensive Insulin Use May Preserve β-Cell Function in Neonatal Diabetes Due to Mutations in the Proinsulin Gene. Journal of the Endocrine Society. 2: 1-8. PMID 29308449 DOI: 10.1210/Js.2017-00356  0.402
2018 Vierra NC, Dickerson MT, Philipson LH, Jacobson DA. Simultaneous Real-Time Measurement of the β-Cell Membrane Potential and Ca(2+) Influx to Assess the Role of Potassium Channels on β-Cell Function. Methods in Molecular Biology (Clifton, N.J.). 1684: 73-84. PMID 29058185 DOI: 10.1007/978-1-4939-7362-0_7  0.32
2018 Bosi E, Geyer S, Sosenko J, Becker DJ, Battaglia M, Ismail HM, Atkinson MA, Philipson LH, Palmer JP, Evans-Molina C. Metabolic Markers Associated with Increased Risk for Progression from Single to Multiple Autoantibodies in Type 1 Diabetes Relatives Diabetes. 67. DOI: 10.2337/Db18-94-Or  0.32
2018 Sanyoura M, Letourneau LR, Naylor RN, Philipson LH, Weedon MN, Oram RA, Greeley SAW. Clinical Utility of the T1D Genetic Risk Score—Examples from the U.S. Monogenic Diabetes Registry Diabetes. 67. DOI: 10.2337/Db18-264-Or  0.315
2018 Dickens LT, Letourneau LR, Sanyoura M, Philipson LH, Greeley SAW, Naylor RN. Identifying Patients with GDM at Risk for GCK-MODY Diabetes. 67. DOI: 10.2337/Db18-2353-Pub  0.354
2018 Dickens LT, Letourneau LR, Philipson LH, Greeley SAW, Naylor RN. Management of GCK-MODY in Pregnancy—Does Clinical Practice Follow Current Recommendations? Diabetes. 67. DOI: 10.2337/Db18-1453-P  0.301
2018 Letourneau LR, Carmody D, Denson AM, Sanyoura M, Naylor RN, Philipson LH, Greeley SAW. Insulin Treatment and Clinical Outcomes in 67 Participants with Infancy-Onset Diabetes Diabetes. 67. DOI: 10.2337/Db18-1379-P  0.37
2017 Gołębiewska JE, Solomina J, Thomas C, Kijek M, Bachul P, Basto L, Golab K, Wang LJ, Fillman N, Tibudan M, Cieply K, Philipson L, Dębska-Ślizień A, Millis JM, Fung J, et al. Comparative evaluation of simple indices using a single fasting blood sample to estimate beta cell function after islet transplantation. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 29218834 DOI: 10.1111/Ajt.14620  0.317
2017 Hwang JL, Park SY, Ye H, Sanyoura M, Pastore AN, Carmody D, Del Gaudio D, Wilson JF, Hanis CL, Liu X, Atzmon G, Glaser B, Philipson LH, Greeley SAW. FOXP3 mutations causing early-onset insulin-requiring diabetes but without other features of immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome. Pediatric Diabetes. PMID 29193502 DOI: 10.1111/Pedi.12612  0.385
2017 Bergeron V, Ghislain J, Vivot K, Tamarina N, Philipson LH, Fielitz J, Poitout V. Deletion of Protein Kinase D1 in Pancreatic Beta Cells Impairs Insulin Secretion in High-Fat Fed Mice. Diabetes. PMID 29038309 DOI: 10.2337/Db17-0982  0.368
2017 Sanyoura M, Jacobsen L, Carmody D, Gaudio DD, Alkorta-Aranburu G, Arndt K, Hu YY, Kobiernicki F, Kusmartseva I, Atkinson MA, Philipson LH, Schatz D, Campbell-Thompson M, Greeley SAW. Pancreatic Histopathology of Human Monogenic Diabetes Due to Causal Variants in KCNJ11, HNF1A, GATA6, and LMNA. The Journal of Clinical Endocrinology and Metabolism. PMID 28938416 DOI: 10.1210/Jc.2017-01159  0.365
2017 Letourneau LR, Carmody D, Wroblewski K, Denson AM, Sanyoura M, Naylor RN, Philipson LH, Greeley SAW. Diabetes Presentation in Infancy: High Risk of Diabetic Ketoacidosis. Diabetes Care. 40: e147-e148. PMID 28779000 DOI: 10.2337/Dc17-1145  0.368
2017 Fridlyand L, Philipson LH. Computational Model of Cellular Energy Homeostasis and ROS Dynamics for Nonmuscle and Cancer Cells Biophysical Journal. 112: 283. DOI: 10.1016/J.Bpj.2016.11.1533  0.303
2016 Greeley SA, Zielinski MC, Poudel A, Ye H, Berry S, Taxy JB, Carmody D, Steiner DF, Philipson LH, Wood JR, Hara M. Case Report: Preservation of Reduced Numbers of Insulin-Positive Cells in Sulfonylurea-Unresponsive KCNJ11-related Diabetes. The Journal of Clinical Endocrinology and Metabolism. jc20162826. PMID 27802092 DOI: 10.1210/Jc.2016-2826  0.399
2016 Fridlyand LE, Tamarina NA, Schally AV, Philipson LH. Growth Hormone-Releasing Hormone in Diabetes. Frontiers in Endocrinology. 7: 129. PMID 27777568 DOI: 10.3389/Fendo.2016.00129  0.428
2016 Carmody D, Pastore AN, Landmeier KA, Letourneau LR, Martin R, Hwang JL, Naylor RN, Hunter SJ, Msall ME, Philipson LH, Scott MN, Greeley SA. Patients with KCNJ11-related diabetes frequently have neuropsychological impairments compared with sibling controls. Diabetic Medicine : a Journal of the British Diabetic Association. PMID 27223594 DOI: 10.1111/Dme.13159  0.345
2016 Rosario W, Singh I, Wautlet A, Patterson C, Flak J, Becker TC, Ali A, Tamarina N, Philipson LH, Enquist LW, Myers MG, Rhodes CJ. The Brain to Pancreatic Islet Neuronal Map Reveals Differential Glucose Regulation from Distinct Hypothalamic Regions. Diabetes. PMID 27207534 DOI: 10.2337/Db15-0629  0.358
2016 Fridlyand LE, Philipson LH. Pancreatic Beta Cell G-Protein Coupled Receptors and Second Messenger Interactions: A Systems Biology Computational Analysis. Plos One. 11: e0152869. PMID 27138453 DOI: 10.1371/Journal.Pone.0152869  0.388
2016 Carmody D, Naylor RN, Bell CD, Berry S, Montgomery JT, Tadie EC, Hwang JL, Greeley SA, Philipson LH. GCK-MODY in the US National Monogenic Diabetes Registry: frequently misdiagnosed and unnecessarily treated. Acta Diabetologica. PMID 27106716 DOI: 10.1007/S00592-016-0859-8  0.352
2016 Yi Y, Sun X, Gibson-Corley K, Xie W, Liang B, He N, Tyler SR, Uc A, Philipson LH, Wang K, Hara M, Larson Ode K, Norris AW, Engelhardt JF. A Transient Metabolic Recovery from Early Life Glucose Intolerance in Cystic Fibrosis Ferrets Occurs During Pancreatic Remodeling. Endocrinology. en20151935. PMID 26862997 DOI: 10.1210/En.2015-1935  0.373
2016 Naylor R, Montgomery J, Lindauer K, Letourneau L, Bindal A, Sanyoura M, Carmody D, Greeley S, Philipson L. Id: 23: Long Delay In Accurate Diagnosis Of Hnf1A-Mody In The Us Monogenic Diabetes Registry Journal of Investigative Medicine. 64: 934-934. DOI: 10.1136/Jim-2016-000120.47  0.4
2015 Campbell JE, Ussher JR, Mulvihill EE, Kolic J, Baggio LL, Cao X, Liu Y, Lamont BJ, Morii T, Streutker CJ, Tamarina N, Philipson LH, Wrana JL, MacDonald PE, Drucker DJ. TCF1 links GIPR signaling to the control of beta cell function and survival. Nature Medicine. PMID 26642437 DOI: 10.1038/Nm.3997  0.392
2015 Oropeza D, Jouvet N, Bouyakdan K, Perron G, Ringuette LJ, Philipson LH, Kiss RS, Poitout V, Alquier T, Estall JL. PGC-1 coactivators in β-cells regulate lipid metabolism and are essential for insulin secretion coupled to fatty acids. Molecular Metabolism. 4: 811-22. PMID 26629405 DOI: 10.1016/J.Molmet.2015.08.001  0.404
2015 Fan F, Ji C, Wu Y, Ferguson SM, Tamarina N, Philipson LH, Lou X. Dynamin 2 regulates biphasic insulin secretion and plasma glucose homeostasis. The Journal of Clinical Investigation. PMID 26413867 DOI: 10.1172/Jci80652  0.411
2015 Perrone ME, Carmody D, Philipson LH, Greeley SA. An online monogenic diabetes discussion group: supporting families and fueling new research. Translational Research : the Journal of Laboratory and Clinical Medicine. 166: 425-31. PMID 26184072 DOI: 10.1016/J.Trsl.2015.06.013  0.317
2015 Swisa A, Granot Z, Tamarina N, Sayers S, Bardeesy N, Philipson L, Hodson DJ, Wikstrom JD, Rutter GA, Leibowitz G, Glaser B, Dor Y. Loss of Liver Kinase B1 (LKB1) in Beta Cells Enhances Glucose-stimulated Insulin Secretion Despite Profound Mitochondrial Defects. The Journal of Biological Chemistry. 290: 20934-46. PMID 26139601 DOI: 10.1074/Jbc.M115.639237  0.359
2015 Carmody D, Park SY, Ye H, Perrone ME, Alkorta-Aranburu G, Highland HM, Hanis CL, Philipson LH, Bell GI, Greeley SA. Continued lessons from the INS gene: an intronic mutation causing diabetes through a novel mechanism. Journal of Medical Genetics. PMID 26101329 DOI: 10.1136/Jmedgenet-2015-103220  0.359
2015 Carmody D, Naylor RN, Philipson LH. Insulin dosing in pediatric diabetic ketoacidosis: where to start? Jama. 313: 2274-5. PMID 26057288 DOI: 10.1001/Jama.2015.135  0.362
2015 Carmody D, Beca FA, Bell CD, Hwang JL, Dickens JT, Devine NA, Mackay DJ, Temple IK, Hays LR, Naylor RN, Philipson LH, Greeley SA. Role of noninsulin therapies alone or in combination in chromosome 6q24-related transient neonatal diabetes: sulfonylurea improves but does not always normalize insulin secretion. Diabetes Care. 38: e86-7. PMID 25998302 DOI: 10.2337/Dc14-3056  0.386
2015 Thurber BW, Carmody D, Tadie EC, Pastore AN, Dickens JT, Wroblewski KE, Naylor RN, Philipson LH, Greeley SA. Age at the time of sulfonylurea initiation influences treatment outcomes in KCNJ11-related neonatal diabetes. Diabetologia. 58: 1430-5. PMID 25877689 DOI: 10.1007/S00125-015-3593-9  0.37
2015 Rajan S, Dickson LM, Mathew E, Orr CM, Ellenbroek JH, Philipson LH, Wicksteed B. Chronic hyperglycemia downregulates GLP-1 receptor signaling in pancreatic β-cells via protein kinase A. Molecular Metabolism. 4: 265-76. PMID 25830090 DOI: 10.1016/J.Molmet.2015.01.010  0.385
2015 Ducat L, Rubenstein A, Philipson LH, Anderson BJ. A review of the mental health issues of diabetes conference. Diabetes Care. 38: 333-8. PMID 25614689 DOI: 10.2337/Dc14-1383  0.322
2015 Philipson LH, Bell G, Polonsky KS. Donald F. Steiner MD, 1930-2014: discoverer of proinsulin. Proceedings of the National Academy of Sciences of the United States of America. 112: 940-1. PMID 25561547 DOI: 10.1073/Pnas.1423774112  0.302
2015 Thomas CC, Philipson LH. Update on diabetes classification. The Medical Clinics of North America. 99: 1-16. PMID 25456640 DOI: 10.1016/J.Mcna.2014.08.015  0.362
2015 Kim K, Oh CM, Ohara-Imaizumi M, Park S, Namkung J, Yadav VK, Tamarina NA, Roe MW, Philipson LH, Karsenty G, Nagamatsu S, German MS, Kim H. Functional role of serotonin in insulin secretion in a diet-induced insulin-resistant state. Endocrinology. 156: 444-52. PMID 25426873 DOI: 10.1210/En.2014-1687  0.331
2015 Hara M, Fowler JL, Bell GI, Philipson LH. Resting beta-cells - A functional reserve? Diabetes and Metabolism. DOI: 10.1016/J.Diabet.2016.01.001  0.37
2015 Fridlyand LE, Philipson LH. Computational System Analysis of Ca2+ Signaling in the Pancreatic Beta-Cells Biophysical Journal. 108. DOI: 10.1016/J.Bpj.2014.11.593  0.322
2014 Tamarina NA, Roe MW, Philipson LH. Characterization of mice expressing Ins1 gene promoter driven CreERT recombinase for conditional gene deletion in pancreatic β-cells Islets. 6. PMID 25483876 DOI: 10.4161/Isl.27685  0.314
2014 Carmody D, Bell CD, Hwang JL, Dickens JT, Sima DI, Felipe DL, Zimmer CA, Davis AO, Kotlyarevska K, Naylor RN, Philipson LH, Greeley SA. Sulfonylurea treatment before genetic testing in neonatal diabetes: pros and cons. The Journal of Clinical Endocrinology and Metabolism. 99: E2709-14. PMID 25238204 DOI: 10.1210/Jc.2014-2494  0.367
2014 Ducat L, Philipson LH, Anderson BJ. The mental health comorbidities of diabetes. Jama. 312: 691-2. PMID 25010529 DOI: 10.1001/Jama.2014.8040  0.304
2014 Liew CW, Assmann A, Templin AT, Raum JC, Lipson KL, Rajan S, Qiang G, Hu J, Kawamori D, Lindberg I, Philipson LH, Sonenberg N, Goldfine AB, Stoffers DA, Mirmira RG, et al. Insulin regulates carboxypeptidase E by modulating translation initiation scaffolding protein eIF4G1 in pancreatic β cells. Proceedings of the National Academy of Sciences of the United States of America. 111: E2319-28. PMID 24843127 DOI: 10.1073/Pnas.1323066111  0.393
2014 Smith EP, An Z, Wagner C, Lewis AG, Cohen EB, Li B, Mahbod P, Sandoval D, Perez-Tilve D, Tamarina N, Philipson LH, Stoffers DA, Seeley RJ, D'Alessio DA. The role of β cell glucagon-like peptide-1 signaling in glucose regulation and response to diabetes drugs. Cell Metabolism. 19: 1050-7. PMID 24836562 DOI: 10.1016/J.Cmet.2014.04.005  0.356
2014 Sui H, Yi Y, Yao J, Liang B, Sun X, Hu S, Uc A, Nelson DJ, Ode KL, Philipson LH, Engelhardt JF, Norris AW. Quantifying insulin sensitivity and entero-insular responsiveness to hyper- and hypoglycemia in ferrets. Plos One. 9: e90519. PMID 24594704 DOI: 10.1371/Journal.Pone.0090519  0.393
2014 Coleman NJ, Miernik J, Philipson L, Fogelfeld L. Lean versus obese diabetes mellitus patients in the United States minority population. Journal of Diabetes and Its Complications. 28: 500-5. PMID 24581791 DOI: 10.1016/J.Jdiacomp.2013.11.010  0.338
2014 Tornovsky-Babeay S, Dadon D, Ziv O, Tzipilevich E, Kadosh T, Schyr-Ben Haroush R, Hija A, Stolovich-Rain M, Furth-Lavi J, Granot Z, Porat S, Philipson LH, Herold KC, Bhatti TR, Stanley C, et al. Type 2 diabetes and congenital hyperinsulinism cause DNA double-strand breaks and p53 activity in β cells. Cell Metabolism. 19: 109-21. PMID 24332968 DOI: 10.1016/J.Cmet.2013.11.007  0.384
2014 Shalev SA, Tenenbaum-Rakover Y, Horovitz Y, Paz VP, Ye H, Carmody D, Highland HM, Boerwinkle E, Hanis CL, Muzny DM, Gibbs RA, Bell GI, Philipson LH, Greeley SA. Microcephaly, epilepsy, and neonatal diabetes due to compound heterozygous mutations in IER3IP1: insights into the natural history of a rare disorder. Pediatric Diabetes. 15: 252-6. PMID 24138066 DOI: 10.1111/Pedi.12086  0.351
2014 Fridlyand LE, Philipson LH. Quantitative Analysis of Receptors and Second Messengers Interactions in Pancreatic Beta Cell Biophysical Journal. 106: 7-7. DOI: 10.1016/J.Bpj.2013.11.3966  0.382
2013 Eames SC, Kinkel MD, Rajan S, Prince VE, Philipson LH. Transgenic zebrafish model of the C43G human insulin gene mutation. Journal of Diabetes Investigation. 4: 157-67. PMID 24843647 DOI: 10.1111/Jdi.12015  0.406
2013 Carmody D, Philipson L. Neonatal diabetes: the brain comes into focus. The Lancet Diabetes & Endocrinology. 1: 167-168. PMID 24622356 DOI: 10.1016/S2213-8587(13)70094-9  0.316
2013 Fridlyand LE, Jacobson DA, Philipson LH. Ion channels and regulation of insulin secretion in human β-cells :A computational systems analysis Islets. 5: 1-15. PMID 23624892 DOI: 10.4161/Isl.24166  0.381
2013 Tabei SM, Burov S, Kim HY, Kuznetsov A, Huynh T, Jureller J, Philipson LH, Dinner AR, Scherer NF. Intracellular transport of insulin granules is a subordinated random walk. Proceedings of the National Academy of Sciences of the United States of America. 110: 4911-6. PMID 23479621 DOI: 10.1073/Pnas.1221962110  0.3
2013 Torres JM, Cox NJ, Philipson LH. Genome wide association studies for diabetes: perspective on results and challenges. Pediatric Diabetes. 14: 90-6. PMID 23350725 DOI: 10.1111/Pedi.12015  0.403
2013 Kaihara KA, Dickson LM, Jacobson DA, Tamarina N, Roe MW, Philipson LH, Wicksteed B. β-Cell-specific protein kinase A activation enhances the efficiency of glucose control by increasing acute-phase insulin secretion. Diabetes. 62: 1527-36. PMID 23349500 DOI: 10.2337/Db12-1013  0.355
2012 Fridlyand LE, Philipson LH. A computational systems analysis of factors regulating α cell glucagon secretion. Islets. 4: 262-83. PMID 23093806 DOI: 10.4161/Isl.22193  0.359
2012 Rajan S, Torres J, Thompson MS, Philipson LH. SUMO downregulates GLP-1-stimulated cAMP generation and insulin secretion. American Journal of Physiology. Endocrinology and Metabolism. 302: E714-23. PMID 22234371 DOI: 10.1152/Ajpendo.00486.2011  0.411
2012 Fridlyand L, Philipson LH. Computational Systems Analysis of Glucose Sensitivity, Electrical Activity and Glucagon Secretion in Pancreatic Alpha-Cells Biophysical Journal. 102. DOI: 10.1016/J.Bpj.2011.11.751  0.359
2012 Tabei SA, Burov S, Hee Kim A, Kuznetsov A, Philipson LH, Dinner AR, Scherer N. Understanding Non Brownian Dynamics of Intracellular Transport Biophysical Journal. 102: 378a. DOI: 10.1016/J.Bpj.2011.11.2067  0.315
2011 Naylor RN, Greeley SA, Bell GI, Philipson LH. Genetics and pathophysiology of neonatal diabetes mellitus. Journal of Diabetes Investigation. 2: 158-69. PMID 24843477 DOI: 10.1111/J.2040-1124.2011.00106.X  0.408
2011 Greeley SA, Naylor RN, Philipson LH, Bell GI. Neonatal diabetes: an expanding list of genes allows for improved diagnosis and treatment. Current Diabetes Reports. 11: 519-32. PMID 21993633 DOI: 10.1007/S11892-011-0234-7  0.407
2011 Fridlyand LE, Philipson LH. Coupling of metabolic, second messenger pathways and insulin granule dynamics in pancreatic beta-cells: a computational analysis. Progress in Biophysics and Molecular Biology. 107: 293-303. PMID 21920379 DOI: 10.1016/J.Pbiomolbio.2011.09.001  0.398
2011 Greeley SA, Naylor RN, Cook LS, Tucker SE, Lipton RB, Philipson LH. Creation of the Web-based University of Chicago Monogenic Diabetes Registry: using technology to facilitate longitudinal study of rare subtypes of diabetes. Journal of Diabetes Science and Technology. 5: 879-86. PMID 21880229 DOI: 10.1177/193229681100500409  0.365
2011 Naylor R, Philipson LH. Who should have genetic testing for maturity-onset diabetes of the young? Clinical Endocrinology. 75: 422-6. PMID 21521318 DOI: 10.1111/J.1365-2265.2011.04049.X  0.396
2011 Greeley SA, John PM, Winn AN, Ornelas J, Lipton RB, Philipson LH, Bell GI, Huang ES. The cost-effectiveness of personalized genetic medicine: the case of genetic testing in neonatal diabetes. Diabetes Care. 34: 622-7. PMID 21273495 DOI: 10.2337/Dc10-1616  0.382
2011 Dadi P, Philipson LH, Jacobson DA. The Two-Pore-Domain Potassium Channels, TASK-1 and TASK-3, regulate Pancreatic Beta-Cell Membrane Potential in Response to pH and Anesthetics Biophysical Journal. 100. DOI: 10.1016/J.Bpj.2010.12.743  0.332
2011 Fridlyand LE, Philipson LH. Ion Channels, Action Potentials and Ca2+ Handling in Human Pancreatic Beta-Cells. a Computational Approach Biophysical Journal. 100. DOI: 10.1016/J.Bpj.2010.12.696  0.32
2011 Støy J, Steiner DF, Park S, Ye H, Philipson LH, Bell GI. Erratum to: Clinical and molecular genetics of neonatal diabetes due to mutations in the insulin gene Reviews in Endocrine and Metabolic Disorders. 13: 79-81. DOI: 10.1007/S11154-011-9158-4  0.358
2010 Støy J, Steiner DF, Park SY, Ye H, Philipson LH, Bell GI. Clinical and molecular genetics of neonatal diabetes due to mutations in the insulin gene. Reviews in Endocrine & Metabolic Disorders. 11: 205-15. PMID 20938745 DOI: 10.1007/S11154-010-9151-3  0.411
2010 Lopez JP, Turner JR, Philipson LH. Glucose-induced ERM protein activation and translocation regulates insulin secretion. American Journal of Physiology. Endocrinology and Metabolism. 299: E772-85. PMID 20739507 DOI: 10.1152/Ajpendo.00199.2010  0.374
2010 Jacobson DA, Mendez F, Thompson M, Torres J, Cochet O, Philipson LH. Calcium-activated and voltage-gated potassium channels of the pancreatic islet impart distinct and complementary roles during secretagogue induced electrical responses. The Journal of Physiology. 588: 3525-37. PMID 20643768 DOI: 10.1113/Jphysiol.2010.190207  0.323
2010 Fridlyand LE, Tamarina N, Philipson LH. Bursting and calcium oscillations in pancreatic β-cells: Specific pacemakers for specific mechanisms American Journal of Physiology - Endocrinology and Metabolism. 299. PMID 20628025 DOI: 10.1152/Ajpendo.00177.2010  0.31
2010 Marcheva B, Ramsey KM, Buhr ED, Kobayashi Y, Su H, Ko CH, Ivanova G, Omura C, Mo S, Vitaterna MH, Lopez JP, Philipson LH, Bradfield CA, Crosby SD, JeBailey L, et al. Disruption of the clock components CLOCK and BMAL1 leads to hypoinsulinaemia and diabetes. Nature. 466: 627-31. PMID 20562852 DOI: 10.1038/Nature09253  0.419
2010 Eames SC, Philipson LH, Prince VE, Kinkel MD. Blood sugar measurement in zebrafish reveals dynamics of glucose homeostasis. Zebrafish. 7: 205-13. PMID 20515318 DOI: 10.1089/Zeb.2009.0640  0.326
2010 Fridlyand LE, Philipson LH. Glucose sensing in the pancreatic beta cell: a computational systems analysis. Theoretical Biology & Medical Modelling. 7: 15. PMID 20497556 DOI: 10.1186/1742-4682-7-15  0.356
2010 Greeley SA, Tucker SE, Naylor RN, Bell GI, Philipson LH. Neonatal diabetes mellitus: a model for personalized medicine. Trends in Endocrinology and Metabolism: Tem. 21: 464-72. PMID 20434356 DOI: 10.1016/J.Tem.2010.03.004  0.402
2010 Greeley SA, Tucker SE, Worrell HI, Skowron KB, Bell GI, Philipson LH. Update in neonatal diabetes. Current Opinion in Endocrinology, Diabetes, and Obesity. 17: 13-9. PMID 19952737 DOI: 10.1097/Med.0B013E328334F158  0.406
2010 Rajan S, Eames SC, Park SY, Labno C, Bell GI, Prince VE, Philipson LH. In vitro processing and secretion of mutant insulin proteins that cause permanent neonatal diabetes. American Journal of Physiology. Endocrinology and Metabolism. 298: E403-10. PMID 19952343 DOI: 10.1152/Ajpendo.00592.2009  0.408
2009 Steiner DF, Park SY, Støy J, Philipson LH, Bell GI. A brief perspective on insulin production. Diabetes, Obesity & Metabolism. 11: 189-96. PMID 19817801 DOI: 10.1111/J.1463-1326.2009.01106.X  0.404
2009 Deriy LV, Gomez EA, Jacobson DA, Wang X, Hopson JA, Liu XY, Zhang G, Bindokas VP, Philipson LH, Nelson DJ. The granular chloride channel ClC-3 is permissive for insulin secretion. Cell Metabolism. 10: 316-23. PMID 19808024 DOI: 10.1016/J.Cmet.2009.08.012  0.372
2009 Gimi B, Kwon J, Kuznetsov A, Vachha B, Magin RL, Philipson LH, Lee JB. A nanoporous, transparent microcontainer for encapsulated islet therapy. Journal of Diabetes Science and Technology. 3: 297-303. PMID 19746206 DOI: 10.1177/193229680900300210  0.315
2009 Kumaraguru J, Flanagan SE, Greeley SA, Nuboer R, Støy J, Philipson LH, Hattersley AT, Rubio-Cabezas O. Tooth discoloration in patients with neonatal diabetes after transfer onto glibenclamide: a previously unreported side effect. Diabetes Care. 32: 1428-30. PMID 19435956 DOI: 10.2337/Dc09-0280  0.32
2009 Chen WS, Peng XD, Wang Y, Xu PZ, Chen ML, Luo Y, Jeon SM, Coleman K, Haschek WM, Bass J, Philipson LH, Hay N. Leptin deficiency and beta-cell dysfunction underlie type 2 diabetes in compound Akt knockout mice. Molecular and Cellular Biology. 29: 3151-62. PMID 19289493 DOI: 10.1128/Mcb.01792-08  0.393
2009 Jacobson DA, Wicksteed BL, Philipson LH. The alpha-cell conundrum: ATP-sensitive K+ channels and glucose sensing. Diabetes. 58: 304-6. PMID 19171747 DOI: 10.2337/Db08-1618  0.382
2009 Monaghan MC, Støy J, Streisand R, Philipson L, Cogen FR. Case study: Transitioning from insulin to glyburide in permanent neonatal diabetes: Medical and psychosocial challenges in an 18-year-old male Clinical Diabetes. 27: 25-29. DOI: 10.2337/Diaclin.27.1.25  0.381
2009 Fridlyand LE, Philipson LH. Mitochondrial Energy Metabolism and Ca2+ Handling in Pancreatic Beta-cells. A System Analysis Approach Biophysical Journal. 96. DOI: 10.1016/J.Bpj.2008.12.936  0.313
2008 Støy J, Greeley SA, Paz VP, Ye H, Pastore AN, Skowron KB, Lipton RB, Cogen FR, Bell GI, Philipson LH. Diagnosis and treatment of neonatal diabetes: a United States experience. Pediatric Diabetes. 9: 450-9. PMID 18662362 DOI: 10.1111/J.1399-5448.2008.00433.X  0.357
2008 Tamarina NA, Kuznetsov A, Philipson LH. Reversible translocation of EYFP-tagged STIM1 is coupled to calcium influx in insulin secreting beta-cells. Cell Calcium. 44: 533-44. PMID 18452988 DOI: 10.1016/J.Ceca.2008.03.007  0.337
2008 Philipson LH, Roe MW. When BAD is good for beta cells. Cell Metabolism. 7: 280-1. PMID 18396130 DOI: 10.1016/J.Cmet.2008.03.009  0.329
2008 Adair B, Nunn R, Lewis S, Dukes I, Philipson L, Yeager M. Single particle image reconstruction of the human recombinant Kv2.1 channel. Biophysical Journal. 94: 2106-14. PMID 18212012 DOI: 10.1529/Biophysj.107.118562  0.317
2008 Molven A, Ringdal M, Nordbø AM, Raeder H, Støy J, Lipkind GM, Steiner DF, Philipson LH, Bergmann I, Aarskog D, Undlien DE, Joner G, Søvik O, Bell GI, et al. Mutations in the insulin gene can cause MODY and autoantibody-negative type 1 diabetes. Diabetes. 57: 1131-5. PMID 18192540 DOI: 10.2337/Db07-1467  0.398
2008 Edghill EL, Flanagan SE, Patch AM, Boustred C, Parrish A, Shields B, Shepherd MH, Hussain K, Kapoor RR, Malecki M, MacDonald MJ, Støy J, Steiner DF, Philipson LH, Bell GI, et al. Insulin mutation screening in 1,044 patients with diabetes: mutations in the INS gene are a common cause of neonatal diabetes but a rare cause of diabetes diagnosed in childhood or adulthood. Diabetes. 57: 1034-42. PMID 18162506 DOI: 10.2337/Db07-1405  0.387
2008 Bao S, Jacobson DA, Wohltmann M, Bohrer A, Jin W, Philipson LH, Turk J. Glucose homeostasis, insulin secretion, and islet phospholipids in mice that overexpress iPLA2beta in pancreatic beta-cells and in iPLA2beta-null mice. American Journal of Physiology. Endocrinology and Metabolism. 294: E217-29. PMID 17895289 DOI: 10.1152/Ajpendo.00474.2007  0.356
2008 Kim HY, Jureller JE, Kuznetsov A, Philipson LH, Scherer NF. Quantifying local heterogeneity of in vivo transport dynamics using stochastic scanning multiphoton multifocal microscopy and segmented spatiotemporal image correlation spectroscopy Progress in Biomedical Optics and Imaging - Proceedings of Spie. 6860. DOI: 10.1117/12.763300  0.309
2007 Fridlyand LE, Harbeck MC, Roe MW, Philipson LH. Regulation of cAMP dynamics by Ca2+ and G protein-coupled receptors in the pancreatic beta-cell: a computational approach. American Journal of Physiology. Cell Physiology. 293: C1924-33. PMID 17928534 DOI: 10.1152/Ajpcell.00555.2006  0.329
2007 Jacobson DA, Philipson LH. Action potentials and insulin secretion: New insights into the role of Kv channels Diabetes, Obesity and Metabolism. 9: 89-98. PMID 17919183 DOI: 10.1111/J.1463-1326.2007.00784.X  0.37
2007 Støy J, Edghill EL, Flanagan SE, Ye H, Paz VP, Pluzhnikov A, Below JE, Hayes MG, Cox NJ, Lipkind GM, Lipton RB, Greeley SA, Patch AM, Ellard S, Steiner DF, ... ... Philipson LH, et al. Insulin gene mutations as a cause of permanent neonatal diabetes. Proceedings of the National Academy of Sciences of the United States of America. 104: 15040-4. PMID 17855560 DOI: 10.1073/Pnas.0707291104  0.402
2007 Jacobson DA, Kuznetsov A, Lopez JP, Kash S, Ammälä CE, Philipson LH. Kv2.1 ablation alters glucose-induced islet electrical activity, enhancing insulin secretion. Cell Metabolism. 6: 229-35. PMID 17767909 DOI: 10.1016/J.Cmet.2007.07.010  0.387
2007 Ross LF, Philipson LH. Ethics of hematopoietic stem cell transplantation in type 1 diabetes mellitus. Jama. 298: 285; author reply 28. PMID 17635886 DOI: 10.1001/Jama.298.3.285-A  0.322
2007 Kitiphongspattana K, Khan TA, Ishii-Schrade K, Roe MW, Philipson LH, Gaskins HR. Protective role for nitric oxide during the endoplasmic reticulum stress response in pancreatic beta-cells. American Journal of Physiology. Endocrinology and Metabolism. 292: E1543-54. PMID 17264231 DOI: 10.1152/Ajpendo.00620.2006  0.302
2007 Jacobson DA, Philipson LH. TRP channels of the pancreatic beta cell Handbook of Experimental Pharmacology. 179: 409-424. PMID 17217070 DOI: 10.1007/978-3-540-34891-7_24  0.352
2007 Jacobson DA, Weber CR, Bao S, Turk J, Philipson LH. Modulation of the pancreatic islet beta-cell-delayed rectifier potassium channel Kv2.1 by the polyunsaturated fatty acid arachidonate. The Journal of Biological Chemistry. 282: 7442-9. PMID 17197450 DOI: 10.1074/Jbc.M607858200  0.364
2006 Fridlyand LE, Philipson LH. Reactive species, cellular repair and risk factors in the onset of type 2 diabetes mellitus: review and hypothesis. Current Diabetes Reviews. 2: 241-59. PMID 18220630 DOI: 10.2174/157339906776818541  0.385
2006 Yin D, Tao J, Lee DD, Shen J, Hara M, Lopez J, Kuznetsov A, Philipson LH, Chong AS. Recovery of islet beta-cell function in streptozotocin- induced diabetic mice: an indirect role for the spleen. Diabetes. 55: 3256-63. PMID 17130468 DOI: 10.2337/Db05-1275  0.394
2006 Fridlyand LE, Philipson LH. Cold climate genes and the prevalence of type 2 diabetes mellitus. Medical Hypotheses. 67: 1034-41. PMID 16797871 DOI: 10.1016/J.Mehy.2006.04.057  0.31
2006 Gimi B, Leoni L, Oberholzer J, Braun M, Avila J, Wang Y, Desai T, Philipson LH, Magin RL, Roman BB. Functional MR microimaging of pancreatic beta-cell activation. Cell Transplantation. 15: 195-203. PMID 16719054 DOI: 10.3727/000000006783982151  0.364
2006 Jacobson DA, Cho J, Landa LR, Tamarina NA, Roe MW, Buxbaum JD, Philipson LH. Downstream regulatory element antagonistic modulator regulates islet prodynorphin expression. American Journal of Physiology. Endocrinology and Metabolism. 291: E587-95. PMID 16621893 DOI: 10.1152/Ajpendo.00612.2005  0.327
2006 Chong AS, Shen J, Tao J, Yin D, Kuznetsov A, Hara M, Philipson LH. Reversal of diabetes in non-obese diabetic mice without spleen cell-derived beta cell regeneration. Science (New York, N.Y.). 311: 1774-5. PMID 16556844 DOI: 10.1126/Science.1123510  0.366
2006 Fridlyand LE, Philipson LH. Reactive species and early manifestation of insulin resistance in type 2 diabetes Diabetes, Obesity and Metabolism. 8: 136-145. PMID 16448517 DOI: 10.1111/J.1463-1326.2005.00496.X  0.362
2006 Chong AS, Shen J, Tao J, Yin D, Kuznetsov A, Hara M, Philipson LH. Response to Comment on Chong et al. on Diabetes Reversal in NOD Mice Science. 314: 1243-1243. DOI: 10.1126/Science.1129918  0.351
2005 Tamarina NA, Kuznetsov A, Rhodes CJ, Bindokas VP, Philipson LH. Inositol (1,4,5)-trisphosphate dynamics and intracellular calcium oscillations in pancreatic beta-cells. Diabetes. 54: 3073-81. PMID 16249428 DOI: 10.2337/Diabetes.54.11.3073  0.338
2005 Tamarina NA, Kuznetsov A, Fridlyand LE, Philipson LH. Delayed-rectifier (KV2.1) regulation of pancreatic beta-cell calcium responses to glucose: inhibitor specificity and modeling. American Journal of Physiology. Endocrinology and Metabolism. 289: E578-85. PMID 16014354 DOI: 10.1152/Ajpendo.00054.2005  0.351
2005 Fridlyand LE, Ma L, Philipson LH. Adenine nucleotide regulation in pancreatic beta-cells: modeling of ATP/ADP-Ca2+ interactions. American Journal of Physiology. Endocrinology and Metabolism. 289: E839-48. PMID 15985450 DOI: 10.1152/Ajpendo.00595.2004  0.37
2005 Wang CZ, Wang Y, Di A, Magnuson MA, Ye H, Roe MW, Nelson DJ, Bell GI, Philipson LH. 5-amino-imidazole carboxamide riboside acutely potentiates glucose-stimulated insulin secretion from mouse pancreatic islets by KATP channel-dependent and -independent pathways. Biochemical and Biophysical Research Communications. 330: 1073-9. PMID 15823553 DOI: 10.1016/J.Bbrc.2005.03.093  0.377
2005 Kuznetsov A, Bindokas VP, Marks JD, Philipson LH. FRET-based voltage probes for confocal imaging: membrane potential oscillations throughout pancreatic islets. American Journal of Physiology. Cell Physiology. 289: C224-9. PMID 15758044 DOI: 10.1152/Ajpcell.00004.2005  0.327
2004 Fridlyand LE, Philipson LH. Does the glucose-dependent insulin secretion mechanism itself cause oxidative stress in pancreatic beta-cells? Diabetes. 53: 1942-8. PMID 15277370 DOI: 10.2337/Diabetes.53.8.1942  0.349
2004 Ma L, Bindokas VP, Kuznetsov A, Rhodes C, Hays L, Edwardson JM, Ueda K, Steiner DF, Philipson LH. Direct imaging shows that insulin granule exocytosis occurs by complete vesicle fusion. Proceedings of the National Academy of Sciences of the United States of America. 101: 9266-71. PMID 15197259 DOI: 10.1073/Pnas.0403201101  0.319
2003 Tamarina NA, Wang Y, Mariotto L, Kuznetsov A, Bond C, Adelman J, Philipson LH. Small-conductance calcium-activated K+ channels are expressed in pancreatic islets and regulate glucose responses Diabetes. 52: 2000-2006. PMID 12882916 DOI: 10.2337/Diabetes.52.8.2000  0.397
2003 Bindokas VP, Kuznetsov A, Sreenan S, Polonsky KS, Roe MW, Philipson LH. Visualizing superoxide production in normal and diabetic rat islets of Langerhans. The Journal of Biological Chemistry. 278: 9796-801. PMID 12514170 DOI: 10.1074/Jbc.M206913200  0.401
2003 Yaekura K, Julyan R, Wicksteed BL, Hays LB, Alarcon C, Sommers S, Poitout V, Baskin DG, Wang Y, Philipson LH, Rhodes CJ. Insulin secretory deficiency and glucose intolerance in Rab3A null mice. The Journal of Biological Chemistry. 278: 9715-21. PMID 12510060 DOI: 10.1074/Jbc.M211352200  0.398
2002 Qian F, Huang P, Ma L, Kuznetsov A, Tamarina N, Philipson LH. TRP genes: candidates for nonselective cation channels and store-operated channels in insulin-secreting cells. Diabetes. 51: S183-9. PMID 11815479 DOI: 10.2337/Diabetes.51.2007.S183  0.363
2000 Ma L, Tamarina N, Wang Y, Kuznetsov A, Patel N, Kending C, Hering BJ, Philipson LH. Baculovirus-mediated gene transfer into pancreatic islet cells Diabetes. 49: 1986-1991. PMID 11117998 DOI: 10.2337/Diabetes.49.12.1986  0.315
2000 Zhou YP, Pena JC, Roe MW, Mittal A, Levisetti M, Baldwin AC, Pugh W, Ostrega D, Ahmed N, Bindokas VP, Philipson LH, Hanahan D, Thompson CB, Polonsky KS. Overexpression of Bcl-x(L) in beta-cells prevents cell death but impairs mitochondrial signal for insulin secretion. American Journal of Physiology. Endocrinology and Metabolism. 278: E340-51. PMID 10662719 DOI: 10.1152/Ajpendo.2000.278.2.E340  0.349
1998 Dukes ID, Sreenan S, Roe MW, Levisetti M, Zhou Y, Ostrega D, Bell GI, Pontoglio M, Yaniv M, Philipson L, Polonsky KS. Defective Pancreatic β-Cell Glycolytic Signaling in Hepatocyte Nuclear Factor-1α-deficient Mice Journal of Biological Chemistry. 273: 24457-24464. PMID 9733737 DOI: 10.1074/Jbc.273.38.24457  0.401
1997 Dukes ID, Roe MW, Worley JF, Philipson LH. Glucose-induced alterations in β-cell cytoplasmic Ca2+ involving the coupling of intracellular Ca2+ stores and plasma membrane ion channels Current Opinion in Endocrinology & Diabetes. 4: 262-271. DOI: 10.1097/00060793-199708000-00003  0.344
1996 Roe MW, Worley JF, Mittal AA, Kuznetsov A, Dasgupta S, Mertz RJ, Witherspoon SM, Blair N, Lancaster ME, McIntyre MS, Ronald Shehee W, Dukes ID, Philipson LH. Expression and function of pancreatic β-cell delayed rectifier K+ channels. Role in stimulus-secretion coupling Journal of Biological Chemistry. 271: 32241-32246. PMID 8943282 DOI: 10.1074/Jbc.271.50.32241  0.377
1996 Roe MW, Worley JF, Tokuyama Y, Philipson LH, Sturis J, Tang J, Dukes ID, Bell GI, Polonsky KS. NIDDM is associated with loss of pancreatic beta-cell L-type Ca2+ channel activity. The American Journal of Physiology. 270: E133-40. PMID 8772485 DOI: 10.1152/Ajpendo.1996.270.1.E133  0.435
1996 Dukes ID, Philipson LH. K+ channels: Generating excitement in pancreatic β-cells Diabetes. 45: 845-853. PMID 8666132 DOI: 10.2337/Diab.45.7.845  0.322
1995 Philipson LH, Kuznetsov A, Toth PT, Murphy JF, Szabo G, Ma GH, Miller RJ. Functional expression of an epitope-tagged G protein-coupled K+ channel (GIRK1) Journal of Biological Chemistry. 270: 14604-14610. PMID 7540174 DOI: 10.1074/Jbc.270.24.14604  0.312
1995 Philipson LH. ATP-sensitive K+ channels: Paradigm lost, paradigm regained Science. 270: 1159. PMID 7502039 DOI: 10.1126/Science.270.5239.1159  0.31
1993 Philipson LH, Kusnetsov A, Larson T, Zeng Y, Westermark G. Human, rodent, and canine pancreatic β-cells express a sodium channel α1-subunit related to a fetal brain isoform Diabetes. 42: 1372-1377. PMID 8394258 DOI: 10.2337/Diab.42.9.1372  0.339
1993 Philipson LH, Malayev A, Kuznetsov A, Chang C, Nelson DJ. Functional and biochemical characterization of the human potassium channel Kv1.5 with a transplanted carboxyl-terminal epitope in stable mammalian cell lines Bba - Biomembranes. 1153: 111-121. PMID 7694656 DOI: 10.1016/0005-2736(93)90282-5  0.301
1992 Coccia EM, Cicala C, Charlesworth A, Ciccarelli C, Rossi GB, Philipson L, Sorrentino V. Regulation and expression of a growth arrest-specific gene (gas5) during growth, differentiation, and development. Molecular and Cellular Biology. 12: 3514-3521. PMID 1630459 DOI: 10.1128/Mcb.12.8.3514  0.303
1991 Philipson LH, Hice RE, Schaefer K, Lamendola J, Bell GI, Nelson DJ, Steiner DF. Sequence and functional expression in Xenopus oocytes of a human insulinoma and islet potassium channel Proceedings of the National Academy of Sciences of the United States of America. 88: 53-57. PMID 1986382 DOI: 10.1073/Pnas.88.1.53  0.326
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