Scott G. Kennedy - Publications

Affiliations: 
Genetics Harvard Medical School, Boston, MA, United States 

36 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Zhao C, Cai S, Shi R, Li X, Deng B, Li R, Yang S, Huang J, Liang Y, Lu P, Yuan Z, Jia H, Jiang Z, Zhang X, Kennedy S, et al. HERD-1 mediates multiphase condensate immiscibility to regulate small RNA-driven transgenerational epigenetic inheritance. Nature Cell Biology. PMID 39354132 DOI: 10.1038/s41556-024-01514-8  0.457
2024 Chen X, Wang K, Mufti FUD, Xu D, Zhu C, Huang X, Zeng C, Jin Q, Huang X, Yan YH, Dong MQ, Feng X, Shi Y, Kennedy S, Guang S. Germ granule compartments coordinate specialized small RNA production. Nature Communications. 15: 5799. PMID 38987544 DOI: 10.1038/s41467-024-50027-3  0.478
2022 Wang SY, Kim K, O'Brown ZK, Levan A, Dodson AE, Kennedy SG, Chernoff C, Greer EL. Hypoxia induces transgenerational epigenetic inheritance of small RNAs. Cell Reports. 41: 111800. PMID 36516753 DOI: 10.1016/j.celrep.2022.111800  0.391
2022 Roschdi S, Yan J, Nomura Y, Escobar CA, Petersen RJ, Bingman CA, Tonelli M, Vivek R, Montemayor EJ, Wickens M, Kennedy SG, Butcher SE. An atypical RNA quadruplex marks RNAs as vectors for gene silencing. Nature Structural & Molecular Biology. 29: 1113-1121. PMID 36352138 DOI: 10.1038/s41594-022-00854-z  0.495
2022 Herman C, Bradley C, Gordon A, Wang C, Cooke M, Kohrn B, Kennedy S, Lichtarge O, Ronca S. RNA polymerase inaccuracy underlies SARS-CoV-2 variants and vaccine heterogeneity. Research Square. PMID 35677076 DOI: 10.21203/rs.3.rs-1690086/v1  0.361
2021 Shukla A, Perales R, Kennedy S. piRNAs coordinate poly(UG) tailing to prevent aberrant and perpetual gene silencing. Current Biology : Cb. PMID 34428467 DOI: 10.1016/j.cub.2021.07.076  0.551
2021 Shukla A, Yan J, Pagano DJ, Dodson AE, Fei Y, Gorham J, Seidman JG, Wickens M, Kennedy S. Author Correction: poly(UG)-tailed RNAs in genome protection and epigenetic inheritance. Nature. PMID 33854240 DOI: 10.1038/s41586-021-03364-y  0.376
2021 Wan G, Bajaj L, Fields B, Dodson AE, Pagano D, Fei Y, Kennedy S. ZSP-1 is a Z granule surface protein required for Z granule fluidity and germline immortality in Caenorhabditis elegans. The Embo Journal. e105612. PMID 33438773 DOI: 10.15252/embj.2020105612  0.36
2020 Wan G, Yan J, Fei Y, Pagano DJ, Kennedy S. A Conserved NRDE-2/MTR-4 Complex Mediates Nuclear RNAi in . Genetics. PMID 33055090 DOI: 10.1534/genetics.120.303631  0.466
2020 Shukla A, Yan J, Pagano DJ, Dodson AE, Fei Y, Gorham J, Seidman JG, Wickens M, Kennedy S. poly(UG)-tailed RNAs in genome protection and epigenetic inheritance. Nature. PMID 32499657 DOI: 10.1038/S41586-020-2323-8  0.572
2019 Dodson AE, Kennedy S. Germ Granules Coordinate RNA-Based Epigenetic Inheritance Pathways. Developmental Cell. PMID 31402284 DOI: 10.1016/J.Devcel.2019.07.025  0.605
2019 Fields BD, Kennedy S. Chromatin Compaction by Small RNAs and the Nuclear RNAi Machinery in C. elegans. Scientific Reports. 9: 9030. PMID 31227740 DOI: 10.1038/S41598-019-45052-Y  0.578
2018 Jiao AL, Perales R, Umbreit NT, Haswell JR, Piper ME, Adams BD, Pellman D, Kennedy S, Slack FJ. Human Nuclear RNAi-Defective 2 (NRDE2) is an essential RNA splicing factor. Rna (New York, N.Y.). PMID 30538148 DOI: 10.1261/Rna.069773.118  0.7
2018 Perales R, Pagano D, Wan G, Fields BD, Saltzman AL, Kennedy SG. Transgenerational Epigenetic Inheritance Is Negatively Regulated by the HERI-1 Chromodomain Protein. Genetics. PMID 30389807 DOI: 10.1534/Genetics.118.301456  0.582
2018 Wan G, Fields BD, Spracklin G, Shukla A, Phillips CM, Kennedy S. Spatiotemporal regulation of liquid-like condensates in epigenetic inheritance. Nature. PMID 29769721 DOI: 10.1038/S41586-018-0132-0  0.696
2018 Kennedy S. Decision letter: Reactivation of RNA metabolism underlies somatic restoration after adult reproductive diapause in C. elegans Elife. DOI: 10.7554/Elife.36194.034  0.426
2017 Spracklin G, Fields B, Wan G, Vijayendran D, Wallig A, Shukla A, Kennedy S. Identification and Characterization of Caenorhabditis elegans RNAi Inheritance Machinery. Genetics. PMID 28533440 DOI: 10.1534/Genetics.116.198812  0.589
2013 Juang BT, Gu C, Starnes L, Palladino F, Goga A, Kennedy S, L'Etoile ND. Endogenous nuclear RNAi mediates behavioral adaptation to odor. Cell. 154: 1010-22. PMID 23993094 DOI: 10.1016/J.Cell.2013.08.006  0.448
2012 Buckley BA, Burkhart KB, Gu SG, Spracklin G, Kershner A, Fritz H, Kimble J, Fire A, Kennedy S. A nuclear Argonaute promotes multigenerational epigenetic inheritance and germline immortality. Nature. 489: 447-51. PMID 22810588 DOI: 10.1038/Nature11352  0.616
2012 Gu SG, Pak J, Guang S, Maniar JM, Kennedy S, Fire A. Amplification of siRNA in Caenorhabditis elegans generates a transgenerational sequence-targeted histone H3 lysine 9 methylation footprint. Nature Genetics. 44: 157-64. PMID 22231482 DOI: 10.1038/Ng.1039  0.446
2011 Burton NO, Burkhart KB, Kennedy S. Nuclear RNAi maintains heritable gene silencing in Caenorhabditis elegans. Proceedings of the National Academy of Sciences of the United States of America. 108: 19683-8. PMID 22106253 DOI: 10.1073/Pnas.1113310108  0.534
2011 Burkhart KB, Guang S, Buckley BA, Wong L, Bochner AF, Kennedy S. A pre-mRNA-associating factor links endogenous siRNAs to chromatin regulation. Plos Genetics. 7: e1002249. PMID 21901112 DOI: 10.1371/Journal.Pgen.1002249  0.545
2010 Guang S, Bochner AF, Burkhart KB, Burton N, Pavelec DM, Kennedy S. Small regulatory RNAs inhibit RNA polymerase II during the elongation phase of transcription. Nature. 465: 1097-101. PMID 20543824 DOI: 10.1038/Nature09095  0.585
2010 Welker NC, Pavelec DM, Nix DA, Duchaine TF, Kennedy S, Bass BL. Dicer's helicase domain is required for accumulation of some, but not all, C. elegans endogenous siRNAs. Rna (New York, N.Y.). 16: 893-903. PMID 20354150 DOI: 10.1261/Rna.2122010  0.496
2010 Gent JI, Lamm AT, Pavelec DM, Maniar JM, Parameswaran P, Tao L, Kennedy S, Fire AZ. Distinct Phases of siRNA Synthesis in an Endogenous RNAi Pathway in C. elegans Soma Molecular Cell. 37: 679-689. PMID 20116306 DOI: 10.1016/J.Molcel.2010.01.012  0.571
2009 Pavelec DM, Lachowiec J, Duchaine TF, Smith HE, Kennedy S. Requirement for the ERI/DICER complex in endogenous RNA interference and sperm development in Caenorhabditis elegans. Genetics. 183: 1283-95. PMID 19797044 DOI: 10.1534/Genetics.109.108134  0.613
2008 Guang S, Bochner AF, Pavelec DM, Burkhart KB, Harding S, Lachowiec J, Kennedy S. An Argonaute transports siRNAs from the cytoplasm to the nucleus. Science (New York, N.Y.). 321: 537-41. PMID 18653886 DOI: 10.1126/Science.1157647  0.593
2006 Duchaine TF, Wohlschlegel JA, Kennedy S, Bei Y, Conte D, Pang K, Brownell DR, Harding S, Mitani S, Ruvkun G, Yates JR, Mello CC. Functional proteomics reveals the biochemical niche of C. elegans DCR-1 in multiple small-RNA-mediated pathways. Cell. 124: 343-54. PMID 16439208 DOI: 10.1016/J.Cell.2005.11.036  0.702
2005 Wang D, Kennedy S, Conte D, Kim JK, Gabel HW, Kamath RS, Mello CC, Ruvkun G. Somatic misexpression of germline P granules and enhanced RNA interference in retinoblastoma pathway mutants. Nature. 436: 593-7. PMID 16049496 DOI: 10.1038/Nature04010  0.714
2005 Sieburth D, Ch'ng Q, Dybbs M, Tavazoie M, Kennedy S, Wang D, Dupuy D, Rual JF, Hill DE, Vidal M, Ruvkun G, Kaplan JM. Systematic analysis of genes required for synapse structure and function. Nature. 436: 510-7. PMID 16049479 DOI: 10.1038/Nature03809  0.678
2005 Kim JK, Gabel HW, Kamath RS, Tewari M, Pasquinelli A, Rual JF, Kennedy S, Dybbs M, Bertin N, Kaplan JM, Vidal M, Ruvkun G. Functional genomic analysis of RNA interference in C. elegans. Science (New York, N.Y.). 308: 1164-7. PMID 15790806 DOI: 10.1126/Science.1109267  0.741
2004 Kennedy S, Wang D, Ruvkun G. A conserved siRNA-degrading RNase negatively regulates RNA interference in C. elegans. Nature. 427: 645-9. PMID 14961122 DOI: 10.1038/Nature02302  0.732
2003 Lee SS, Kennedy S, Tolonen AC, Ruvkun G. DAF-16 target genes that control C. elegans life-span and metabolism. Science (New York, N.Y.). 300: 644-7. PMID 12690206 DOI: 10.1126/Science.1083614  0.617
2003 Li W, Kennedy SG, Ruvkun G. daf-28 encodes a C. elegans insulin superfamily member that is regulated by environmental cues and acts in the DAF-2 signaling pathway. Genes & Development. 17: 844-58. PMID 12654727 DOI: 10.1101/Gad.1066503  0.555
2001 Wert M, Kennedy S, Palfrey HC, Hay N. Myc drives apoptosis in PC12 cells in the absence of Max. Oncogene. 20: 3746-50. PMID 11439337 DOI: 10.1038/Sj.Onc.1204466  0.343
1999 Weihl CC, Ghadge GD, Kennedy SG, Hay N, Miller RJ, Roos RP. Mutant Presenilin-1 Induces Apoptosis and Downregulates Akt/PKB The Journal of Neuroscience. 19: 5360-5369. DOI: 10.1523/Jneurosci.19-13-05360.1999  0.314
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