| Year |
Citation |
Score |
| 2024 |
Kim G, Jarhad DB, Lee G, Kim G, Hou X, Yu J, Lee CS, Warnick E, Gao ZG, Ahn SY, Kwak D, Park K, Lee SD, Park TU, Jung SY, ... ... Jeong LS, et al. Structural Modification and Biological Evaluation of 2,8-Disubstituted Adenine and Its Nucleosides as A Adenosine Receptor Antagonists: Exploring the Roles of Ribose at Adenosine Receptors. Journal of Medicinal Chemistry. PMID 38845345 DOI: 10.1021/acs.jmedchem.4c01003 |
0.48 |
|
| 2024 |
Kim G, Hou X, Byun WS, Kim G, Jarhad DB, Lee G, Hyun YE, Yu J, Lee CS, Qu S, Warnick E, Gao ZG, Kim JY, Ji S, Shin H, ... ... Jeong LS, et al. Correction to "Structure-Activity Relationship of Truncated 2,8-Disubstituted-Adenosine Derivatives as Dual A/A Adenosine Receptor Antagonists and Their Cancer Immunotherapeutic Activity". Journal of Medicinal Chemistry. PMID 38259147 DOI: 10.1021/acs.jmedchem.3c02442 |
0.451 |
|
| 2023 |
Kim G, Hou X, Byun WS, Kim G, Jarhad DB, Lee G, Hyun YE, Yu J, Lee CS, Qu S, Warnick E, Gao ZG, Kim JY, Ji S, Shin H, ... ... Jeong LS, et al. Structure-Activity Relationship of Truncated 2,8-Disubstituted-Adenosine Derivatives as Dual A/A Adenosine Receptor Antagonists and Their Cancer Immunotherapeutic Activity. Journal of Medicinal Chemistry. PMID 37603705 DOI: 10.1021/acs.jmedchem.3c00806 |
0.512 |
|
| 2022 |
Shiriaeva A, Park D, Kim G, Lee Y, Hou X, Jarhad DB, Kim G, Yu J, Hyun YE, Kim W, Gao ZG, Jacobson KA, Han GW, Stevens RC, Jeong LS, et al. GPCR Agonist-to-Antagonist Conversion: Enabling the Design of Nucleoside Functional Switches for the A Adenosine Receptor. Journal of Medicinal Chemistry. PMID 35977382 DOI: 10.1021/acs.jmedchem.2c00462 |
0.468 |
|
| 2022 |
Nguyen M, An S, Nguyen Y, Hyun YE, Choi H, Pham L, Kim JA, Noh M, Kim G, Jeong LS. Design, Synthesis, and Biological Activity of l-1'-Homologated Adenosine Derivatives. Acs Medicinal Chemistry Letters. 13: 1131-1136. PMID 35859875 DOI: 10.1021/acsmedchemlett.2c00159 |
0.331 |
|
| 2021 |
Lee Y, Hou X, Lee JH, Nayak A, Alexander V, Sharma PK, Chang H, Phan K, Gao ZG, Jacobson KA, Choi S, Jeong LS. Subtle Chemical Changes Cross the Boundary between Agonist and Antagonist: New A Adenosine Receptor Homology Models and Structural Network Analysis Can Predict This Boundary. Journal of Medicinal Chemistry. PMID 34435786 DOI: 10.1021/acs.jmedchem.1c00239 |
0.458 |
|
| 2021 |
Choi H, Jacobson KA, Yu J, Jeong LS. Design and Synthesis of 2,6-Disubstituted-4'-Selenoadenosine-5'-,-Dimethyluronamide Derivatives as Human A Adenosine Receptor Antagonists. Pharmaceuticals (Basel, Switzerland). 14. PMID 33920062 DOI: 10.3390/ph14040363 |
0.527 |
|
| 2020 |
An S, Kim G, Kim HJ, Ahn S, Kim HY, Ko H, Hyun YE, Nguyen M, Jeong J, Liu Z, Han J, Choi H, Yu J, Kim JW, Lee HW, ... ... Jeong LS, et al. Discovery and Structure-Activity Relationships of Novel Template, Truncated 1'-Homologated Adenosine Derivatives as Pure Dual PPARγ/δ Modulators. Journal of Medicinal Chemistry. PMID 33325691 DOI: 10.1021/acs.jmedchem.0c01874 |
0.48 |
|
| 2019 |
Shin YS, Jarhad DB, Jang MH, Kovacikova K, Kim G, Yoon JS, Kim HR, Hyun YE, Tipnis AS, Chang TS, van Hemert MJ, Jeong LS. Identification of 6'-β-fluoro-homoaristeromycin as a potent inhibitor of chikungunya virus replication. European Journal of Medicinal Chemistry. 187: 111956. PMID 31841728 DOI: 10.1016/j.ejmech.2019.111956 |
0.322 |
|
| 2019 |
An S, Yu J, Choi H, Ko H, Ahn S, Shin JC, Pyo JJ, Jeong LS, Noh M. Selenium bioisosteric replacement of adenosine derivatives promoting adiponectin secretion increases the binding affinity to peroxisome proliferator-activated receptor δ. Bioorganic & Medicinal Chemistry. 115226. PMID 31806266 DOI: 10.1016/j.bmc.2019.115226 |
0.319 |
|
| 2017 |
Yu J, Ahn S, Kim HJ, Lee M, Ahn S, Kim J, Jin SH, Lee E, Kim G, Cheong JH, Jacobson KA, Jeong LS, Noh M. Polypharmacology of N6-(3-iodobenzyl)adenosine-5'-N-methyluronamide (IB-MECA) and Related A3 Adenosine Receptor Ligands: Peroxisome Proliferator Activated Receptor (PPAR) γ Partial Agonist and PPAR δ Antagonist Activity Suggests Their Anti-diabetic Potential. Journal of Medicinal Chemistry. PMID 28799755 DOI: 10.1021/Acs.Jmedchem.7B00805 |
0.577 |
|
| 2017 |
Sahu PK, Umme T, Yu J, Kim G, Qu S, Naik SD, Jeong LS. Structure-Activity Relationships of Acyclic Selenopurine Nucleosides as Antiviral Agents. Molecules (Basel, Switzerland). 22. PMID 28704950 DOI: 10.3390/molecules22071167 |
0.337 |
|
| 2017 |
Yu J, Zhao LX, Park J, Lee HW, Sahu PK, Cui M, Moss SM, Hammes E, Warnick E, Gao ZG, Noh M, Choi S, Ahn HC, Choi J, Jacobson KA, ... Jeong LS, et al. N6-Substituted-5'-N-Methylcarbamoyl-4'-selenoadenosines as Potent and Selective A3 Adenosine Receptor Agonists with Unusual Sugar Puckering and Nucleobase Orientation. Journal of Medicinal Chemistry. PMID 28380296 DOI: 10.1021/Acs.Jmedchem.7B00241 |
0.52 |
|
| 2016 |
Qu S, Mulamoottil VA, Nayak A, Ryu S, Hou X, Song J, Yu J, Sahu PK, Zhao LX, Choi S, Lee SK, Jeong LS. Design, synthesis, and anticancer activity of C8-substituted-4'-thionucleosides as potential HSP90 inhibitors. Bioorganic & Medicinal Chemistry. PMID 27283788 DOI: 10.1016/j.bmc.2016.05.041 |
0.388 |
|
| 2016 |
Naik SD, Chandra G, Sahu PK, Kim H, Qu S, Yoon J, Jeong LS. Stereo- and regio-selective synthesis of 3′-C-substituted-(N)-methanocarba adenosines as potential anticancer agents Organic Chemistry Frontiers. 3: 1472-1480. DOI: 10.1039/C6QO00358C |
0.332 |
|
| 2016 |
Qu S, Kim G, Yu J, Sahu PK, Choi Y, Naik SD, Jeong LS. Synthesis and Anti-HIV Activity of 5′-Homo-2′,3′-dideoxy-2′,3′-didehydro-4′-selenonucleosides (5′-Homo-4′-Se-d4 Ns) Asian Journal of Organic Chemistry. 5: 735-741. DOI: 10.1002/Ajoc.201600154 |
0.36 |
|
| 2015 |
Sahu PK, Umme T, Yu J, Nayak A, Kim G, Noh M, Lee JY, Kim DD, Jeong LS. Seleno-acyclovir and -ganciclovir: A Discovery of a New Template for Antiviral Agents. Journal of Medicinal Chemistry. PMID 26460883 DOI: 10.1021/acs.jmedchem.5b00804 |
0.318 |
|
| 2015 |
Kim G, Choi Y, Sahu PK, Yu J, Qu S, Lee D, Jeong LS. Stereoselective Synthesis of d-5-Homo-4-selenoribose as a Versatile Intermediate for 4'-Selenonucleosides. Organic Letters. 17: 4636-9. PMID 26348005 DOI: 10.1021/acs.orglett.5b02393 |
0.315 |
|
| 2015 |
Alexander V, Song J, Yu J, Choi JH, Kim JH, Lee SK, Choi WJ, Jeong LS. Synthesis and biological evaluation of 2'-substituted-4'-selenoribofuranosyl pyrimidines as antitumor agents. Archives of Pharmacal Research. 38: 966-72. PMID 25239109 DOI: 10.1007/s12272-014-0466-6 |
0.367 |
|
| 2015 |
Battisti UM, Sorbi C, Quotadamo A, Franchini S, Tait A, Schols D, Jeong LS, Lee SK, Song J, Brasili L. Diastereoselective Synthesis of (1,3-Dioxan-4-yl)pyrimidine and Purin Nucleoside Analogues European Journal of Organic Chemistry. 2015: 1235-1245. DOI: 10.1002/EJOC.201403473 |
0.323 |
|
| 2014 |
Sahu PK, Kim G, Yu J, Ahn JY, Song J, Choi Y, Jin X, Kim JH, Lee SK, Park S, Jeong LS. Stereoselective synthesis of 4'-selenonucleosides via seleno-Michael reaction as potent antiviral agents. Organic Letters. 16: 5796-9. PMID 25340622 DOI: 10.1021/Ol502899B |
0.331 |
|
| 2014 |
Kim JH, Yu J, Alexander V, Choi JH, Song J, Lee HW, Kim HO, Choi J, Lee SK, Jeong LS. Structure-activity relationships of 2'-modified-4'-selenoarabinofuranosyl-pyrimidines as anticancer agents. European Journal of Medicinal Chemistry. 83: 208-25. PMID 24956556 DOI: 10.1016/j.ejmech.2014.06.031 |
0.34 |
|
| 2014 |
Nayak A, Chandra G, Hwang I, Kim K, Hou X, Kim HO, Sahu PK, Roy KK, Yoo J, Lee Y, Cui M, Choi S, Moss SM, Phan K, Gao ZG, ... ... Jeong LS, et al. Synthesis and anti-renal fibrosis activity of conformationally locked truncated 2-hexynyl-N(6)-substituted-(N)-methanocarba-nucleosides as A3 adenosine receptor antagonists and partial agonists. Journal of Medicinal Chemistry. 57: 1344-54. PMID 24456490 DOI: 10.1021/Jm4015313 |
0.585 |
|
| 2014 |
Mulamoottil VA, Nayak A, Jeong LS. Recent Advances in the Synthesis of Carbocyclic Nucleosides via Ring-Closing Metathesis Asian Journal of Organic Chemistry. 3: 748-761. DOI: 10.1002/Ajoc.201402032 |
0.353 |
|
| 2013 |
Peters GJ, Smid K, Vecchi L, Kathmann I, Sarkisjan D, Honeywell RJ, Losekoot N, Ohne O, Orbach A, Blaugrund E, Jeong LS, Lee YB, Ahn CH, Kim DJ. Metabolism, mechanism of action and sensitivity profile of fluorocyclopentenylcytosine (RX-3117; TV-1360). Investigational New Drugs. 31: 1444-57. PMID 24048768 DOI: 10.1007/S10637-013-0025-X |
0.317 |
|
| 2013 |
Kim GD, Oh J, Jeong LS, Lee SK. Thio-Cl-IB-MECA, a novel A₃ adenosine receptor agonist, suppresses angiogenesis by regulating PI3K/AKT/mTOR and ERK signaling in endothelial cells. Biochemical and Biophysical Research Communications. 437: 79-86. PMID 23791876 DOI: 10.1016/J.Bbrc.2013.06.040 |
0.313 |
|
| 2013 |
Yu J, Kim JH, Lee HW, Alexander V, Ahn HC, Choi WJ, Choi J, Jeong LS. New RNA purine building blocks, 4'-selenopurine nucleosides: first synthesis and unusual mixture of sugar puckerings. Chemistry (Weinheim An Der Bergstrasse, Germany). 19: 5528-32. PMID 23553943 DOI: 10.1002/Chem.201300741 |
0.3 |
|
| 2012 |
Choi WJ, Chung HJ, Chandra G, Alexander V, Zhao LX, Lee HW, Nayak A, Majik MS, Kim HO, Kim JH, Lee YB, Ahn CH, Lee SK, Jeong LS. Fluorocyclopentenyl-cytosine with broad spectrum and potent antitumor activity. Journal of Medicinal Chemistry. 55: 4521-5. PMID 22524616 DOI: 10.1021/Jm3004009 |
0.412 |
|
| 2012 |
Chandra G, Majik MS, Lee JY, Jeong LS. Stereoselective synthesis of fluoro-homoneplanocin A as a potential antiviral agent. Organic Letters. 14: 2134-7. PMID 22494389 DOI: 10.1021/Ol300667Q |
0.454 |
|
| 2012 |
Hou X, Majik MS, Kim K, Pyee Y, Lee Y, Alexander V, Chung HJ, Lee HW, Chandra G, Lee JH, Park SG, Choi WJ, Kim HO, Phan K, Gao ZG, ... ... Jeong LS, et al. Structure-activity relationships of truncated C2- or C8-substituted adenosine derivatives as dual acting A₂A and A₃ adenosine receptor ligands. Journal of Medicinal Chemistry. 55: 342-56. PMID 22142423 DOI: 10.1021/Jm201229J |
0.583 |
|
| 2012 |
Majik MS, Yu J, Jeong L. A Straightforward Synthesis of K-7174, a GATA-Specific Inhibitor Bulletin of the Korean Chemical Society. 33: 2903-2906. DOI: 10.5012/Bkcs.2012.33.9.2903 |
0.312 |
|
| 2012 |
Peters GJ, Smid K, Vecchi L, Kathmann I, Loosekoot N, Lee YB, Kim DJ, Ahn C, Jeong LS, Orbach A, Ohne O, Blaugrund E. Abstract 1770: Metabolism and mechanism of action of fluorocyclopentenylcytosine (RX-3117) Cancer Research. 72: 1770-1770. DOI: 10.1158/1538-7445.Am2012-1770 |
0.35 |
|
| 2012 |
Choi WJ, Ko YJ, Chandra G, Lee HW, Kim HO, Koh HJ, Moon HR, Jung YH, Jeong LS. Stereoselective synthesis and anti-HCV activity of conformationally restricted 2′-C-substituted carbanucleosides Tetrahedron. 68: 1253-1261. DOI: 10.1016/J.Tet.2011.11.052 |
0.386 |
|
| 2011 |
Lee HW, Choi WJ, Jacobson KA, Jeong LS. Synthesis and Binding Affinity of Homologated Adenosine Analogues as A3 Adenosine Receptor Ligands. Bulletin of the Korean Chemical Society. 32: 1620-1624. PMID 26120223 DOI: 10.5012/Bkcs.2011.32.5.1620 |
0.593 |
|
| 2011 |
Lee SH, Kim IS, Li QR, Dong GR, Jeong LS, Jung YH. Stereoselective amination of chiral benzylic ethers using chlorosulfonyl isocyanate: total synthesis of (+)-sertraline. The Journal of Organic Chemistry. 76: 10011-9. PMID 22022991 DOI: 10.1021/Jo201794K |
0.353 |
|
| 2011 |
Choi MJ, Chandra G, Lee HW, Hou X, Choi WJ, Phan K, Jacobson KA, Jeong LS. Regio- and stereoselective synthesis of truncated 3'-aminocarbanucleosides and their binding affinity at the A3 adenosine receptor. Organic & Biomolecular Chemistry. 9: 6955-62. PMID 21860878 DOI: 10.1039/C1Ob05853C |
0.601 |
|
| 2011 |
Choi IY, Lee JC, Ju C, Hwang S, Cho GS, Lee HW, Choi WJ, Jeong LS, Kim WK. A3 adenosine receptor agonist reduces brain ischemic injury and inhibits inflammatory cell migration in rats. The American Journal of Pathology. 179: 2042-52. PMID 21854743 DOI: 10.1016/J.Ajpath.2011.07.006 |
0.324 |
|
| 2011 |
Lee HS, Chung HJ, Lee HW, Jeong LS, Lee SK. Suppression of inflammation response by a novel A₃ adenosine receptor agonist thio-Cl-IB-MECA through inhibition of Akt and NF-κB signaling. Immunobiology. 216: 997-1003. PMID 21514967 DOI: 10.1016/J.Imbio.2011.03.008 |
0.343 |
|
| 2011 |
Lee HW, Nam SK, Choi WJ, Kim HO, Jeong LS. Stereoselective synthesis of MLN4924, an inhibitor of NEDD8-activating enzyme. The Journal of Organic Chemistry. 76: 3557-61. PMID 21417215 DOI: 10.1021/Jo2001897 |
0.399 |
|
| 2011 |
Lee KM, Choi WJ, Lee Y, Lee HJ, Zhao LX, Lee HW, Park JG, Kim HO, Hwang KY, Heo YS, Choi S, Jeong LS. X-ray crystal structure and binding mode analysis of human S-adenosylhomocysteine hydrolase complexed with novel mechanism-based inhibitors, haloneplanocin A analogues. Journal of Medicinal Chemistry. 54: 930-8. PMID 21226494 DOI: 10.1021/Jm1010836 |
0.326 |
|
| 2011 |
Lee HW, Choi WJ, Jacobson KA, Jeong LS. Synthesis and binding affinity of homologated adenosine analogues as A3 adenosine receptor ligands Bulletin of the Korean Chemical Society. 32: 1620-1624. DOI: 10.5012/bkcs.2011.32.5.1620 |
0.525 |
|
| 2011 |
Lee HW, Nam SK, Choi WJ, Kim HO, Jeong LS. Synthesis of MLN4924 Synfacts. 2011: 704-704. DOI: 10.1055/S-0030-1260479 |
0.347 |
|
| 2011 |
Lee HW, Nam SK, Choi WJ, Kim HO, Jeong LS. Stereoselective synthesis of MLN4924, an inhibitor of NEDD8-activating enzyme (The Journal of Organic Chemistry (2011) DOI:10.1021/jo2001897) Journal of Organic Chemistry. 76: 3614. DOI: 10.1021/Jo2006329 |
0.303 |
|
| 2011 |
Jeong LS, Yu JH, Lee HW, Choi JH, Choi WJ. Design, Synthesis, and Anti-HCV Activity of 2′-Modified-4′-selenonucleosides Antiviral Research. 90: A70. DOI: 10.1016/J.Antiviral.2011.03.147 |
0.303 |
|
| 2010 |
Hou X, Kim HO, Alexander V, Kim K, Choi S, Park SG, Lee JH, Yoo LS, Gao ZG, Jacobson KA, Jeong LS. Discovery of New Human A(2A) Adenosine Receptor Agonists: Design, Synthesis, and Binding Mode of Truncated 2-Hexynyl-4'-thioadenosine. Acs Medicinal Chemistry Letters. 2010: 516-520. PMID 21286238 DOI: 10.1021/ml1001823 |
0.555 |
|
| 2010 |
Lee HW, Kim HO, Choi WJ, Choi S, Lee JH, Park SG, Yoo L, Jacobson KA, Jeong LS. Design, synthesis, and binding of homologated truncated 4'-thioadenosine derivatives at the human A3 adenosine receptors. Bioorganic & Medicinal Chemistry. 18: 7015-21. PMID 20826090 DOI: 10.1016/J.Bmc.2010.08.018 |
0.565 |
|
| 2010 |
Kim H, Kang JW, Lee S, Choi WJ, Jeong LS, Yang Y, Hong JT, Yoon DY. A3 adenosine receptor antagonist, truncated Thio-Cl-IB-MECA, induces apoptosis in T24 human bladder cancer cells. Anticancer Research. 30: 2823-30. PMID 20683018 |
0.321 |
|
| 2010 |
Choi WJ, Kim YM, Kim HO, Lee HW, Kim DE, Park KS, Chong Y, Jeong LS. Synthesis and anti-hepatitis C virus (HCV) activity of 3'-C-substituted-methyl pyrimidine and purine nucleosides. Bioorganic & Medicinal Chemistry. 18: 4812-20. PMID 20627592 DOI: 10.1016/J.Bmc.2010.05.002 |
0.357 |
|
| 2010 |
Alexander V, Choi WJ, Chun J, Kim HO, Jeon JH, Tosh DK, Lee HW, Chandra G, Choi J, Jeong LS. A new DNA building block, 4'-selenothymidine: synthesis and modification to 4'-seleno-AZT as a potential anti-HIV agent. Organic Letters. 12: 2242-5. PMID 20405850 DOI: 10.1021/Ol1005906 |
0.361 |
|
| 2010 |
Wang Z, Do CW, Avila MY, Peterson-Yantorno K, Stone RA, Gao ZG, Joshi B, Besada P, Jeong LS, Jacobson KA, Civan MM. Nucleoside-derived antagonists to A3 adenosine receptors lower mouse intraocular pressure and act across species. Experimental Eye Research. 90: 146-54. PMID 19878673 DOI: 10.1016/J.Exer.2009.10.001 |
0.55 |
|
| 2010 |
Kim WH, Park AY, Kang JA, Kim J, Kim JA, Lee HR, Chun P, Choi J, Lee CK, Jeong LS, Moon HR. First synthesis of 2′-oxabicyclo[3.1.0]hexyl nucleosides with a north conformation Tetrahedron. 66: 1706-1715. DOI: 10.1016/J.Tet.2010.01.014 |
0.343 |
|
| 2009 |
Park YH, Choi WJ, Tipnis AS, Lee KM, Jeong LS. Truncated fluorocyclopentenyl pyrimidines as S-adenosylhomocysteine hydrolase inhibitors. Nucleosides, Nucleotides & Nucleic Acids. 28: 601-13. PMID 20183604 DOI: 10.1080/15257770903054316 |
0.351 |
|
| 2009 |
Choi WJ, Lee HW, Kim HO, Chinn M, Gao ZG, Patel A, Jacobson KA, Moon HR, Jung YH, Jeong LS. Design and synthesis of N(6)-substituted-4'-thioadenosine-5'-uronamides as potent and selective human A(3) adenosine receptor agonists. Bioorganic & Medicinal Chemistry. 17: 8003-11. PMID 19879151 DOI: 10.1016/J.Bmc.2009.10.011 |
0.535 |
|
| 2009 |
Kim WH, Kang JA, Lee HR, Park AY, Chun P, Lee B, Kim J, Kim JA, Jeong LS, Moon HR. Efficient and practical synthesis of L-hamamelose. Carbohydrate Research. 344: 2317-21. PMID 19818955 DOI: 10.1016/J.Carres.2009.09.011 |
0.351 |
|
| 2009 |
Jeong LS, Tosh DK, Choi WJ, Lee SK, Kang YJ, Choi S, Lee JH, Lee H, Lee HW, Kim HO. Discovery of a new template for anticancer agents: 2'-deoxy-2'-fluoro-4'-selenoarabinofuranosyl-cytosine (2'-F-4'-seleno-ara-C). Journal of Medicinal Chemistry. 52: 5303-6. PMID 19691349 DOI: 10.1021/Jm900852B |
0.379 |
|
| 2009 |
Pal S, Choi WJ, Choe SA, Heller CL, Gao ZG, Chinn M, Jacobson KA, Hou X, Lee SK, Kim HO, Jeong LS. Structure-activity relationships of truncated adenosine derivatives as highly potent and selective human A3 adenosine receptor antagonists. Bioorganic & Medicinal Chemistry. 17: 3733-8. PMID 19375920 DOI: 10.1016/J.Bmc.2009.03.034 |
0.602 |
|
| 2009 |
Lee HR, Kang JA, Park AY, Kim WH, Chun P, Kim J, Kim JA, Lee B, Jeong LS, Moon HR. Synthesis of neplanocin a analog with 2′′-"up"-C-methyl substituent as potential anti-HCV Agent Bulletin of the Korean Chemical Society. 30: 2043-2050. DOI: 10.5012/Bkcs.2009.30.9.2043 |
0.326 |
|
| 2009 |
Yang Z, Kang JA, Kim WH, Park AY, Kim HS, Kim J, Kim JA, Gong P, Jeong LS, Moon HR. Design, synthesis, antitumor activity and mode of action of novel oxiranyl and thiiranyl phenol derivatives Bulletin of the Korean Chemical Society. 30: 1463-1469. DOI: 10.5012/Bkcs.2009.30.7.1463 |
0.328 |
|
| 2009 |
Tosh DK, Jacobson KA, Jeong LS. Nucleoside-based adenosine A3 receptor antagonists as drug candidates Drugs of the Future. 34: 43-52. DOI: 10.1358/Dof.2009.034.01.1286494 |
0.538 |
|
| 2009 |
Lee GE, Joshi BV, Chen W, Jeong LS, Moon HR, Jacobson KA, Kim YC. Corrigendum to "Synthesis and structure-activity relationship studies of tyrosine-based antagonists at the human P2X7 receptor" [Bioorg. Med. Chem. Lett. 18 (2008) 571-575] (DOI:10.1016/j.bmcl.2007.11.077) Bioorganic and Medicinal Chemistry Letters. 19: 556. DOI: 10.1016/J.Bmcl.2008.05.108 |
0.519 |
|
| 2009 |
Yang Z, Kim KR, Park AY, Lee HR, Kang JA, Kim WH, Chun P, Gong P, Lee B, Jeong LS, Moon HR. Highly concise synthesis of 3'-"up"-ethynyl-5'-methylbicyclo- [3.1.0]hexyl purine and pyrimidine nucleoside derivatives using rhodium(II) carbenoid cycloaddition and highly diastereoselective Grignard reaction Chinese Journal of Chemistry. 27: 2405-2412. DOI: 10.1002/Cjoc.201090016 |
0.326 |
|
| 2008 |
Jeong LS, Choi YN, Tosh DK, Choi WJ, Kim HO, Choi J. Design and synthesis of novel 2',3'-dideoxy-4'-selenonucleosides as potential antiviral agents. Bioorganic & Medicinal Chemistry. 16: 9891-7. PMID 18977147 DOI: 10.1016/J.Bmc.2008.10.034 |
0.372 |
|
| 2008 |
Jeong LS, Tosh DK, Choi WJ, Pal S. Synthesis of fluoroneplanocin A Current Protocols in Nucleic Acid Chemistry / Edited by Serge L. Beaucage ... [Et Al.]. PMID 18819082 DOI: 10.1002/0471142700.Nc1406S34 |
0.389 |
|
| 2008 |
Jeong LS, Pal S, Choe SA, Choi WJ, Jacobson KA, Gao ZG, Klutz AM, Hou X, Kim HO, Lee HW, Lee SK, Tosh DK, Moon HR. Structure-activity relationships of truncated D- and l-4'-thioadenosine derivatives as species-independent A3 adenosine receptor antagonists. Journal of Medicinal Chemistry. 51: 6609-13. PMID 18811138 DOI: 10.1021/Jm8008647 |
0.583 |
|
| 2008 |
Liang CW, Choi WJ, Jeong LS. Synthesis of 2-alkynyl substituted 4′-thioadenosine derivatives and their binding affinities at the adenosine receptors Archives of Pharmacal Research. 31: 973-977. PMID 18787783 DOI: 10.1007/S12272-001-1254-X |
0.53 |
|
| 2008 |
Choi WJ, Lee HW, Hou X, Kim HO, Jacobson KA, Jeong LS. Synthesis of 2-chloro-N6-substituted-4'-thioadenosine-5'-N, N-dialkyluronamides as potent and selective A3 adenosine receptor antagonists. Nucleic Acids Symposium Series (2004). 645-6. PMID 18776545 DOI: 10.1093/nass/nrn326 |
0.533 |
|
| 2008 |
Hou X, Pal S, Choi WJ, Kim HO, Tipnis A, Jacobson KA, Jeong LS. Design and synthesis of truncated 4'-thioadenosine derivatives as potent and selective A3 adenosine receptor antagonists. Nucleic Acids Symposium Series (2004). 641-2. PMID 18776543 DOI: 10.1093/nass/nrn324 |
0.566 |
|
| 2008 |
Jeong LS. Development of A3 adenosine receptor ligands. Nucleic Acids Symposium Series (2004). 79-80. PMID 18776262 DOI: 10.1093/nass/nrn040 |
0.353 |
|
| 2008 |
Melman A, Wang B, Joshi BV, Gao ZG, Castro Sd, Heller CL, Kim SK, Jeong LS, Jacobson KA. Selective A(3) adenosine receptor antagonists derived from nucleosides containing a bicyclo[3.1.0]hexane ring system. Bioorganic & Medicinal Chemistry. 16: 8546-56. PMID 18752961 DOI: 10.1016/J.Bmc.2008.08.007 |
0.629 |
|
| 2008 |
Pei X, Choi WJ, Kim YM, Zhao LX, Jeong LS. Synthesis of 3'-C-hydroxymethyl-substituted pyrimidine and purine nucleosides as potential anti-hepatitis C virus (HCV) agents. Archives of Pharmacal Research. 31: 843-9. PMID 18704325 DOI: 10.1007/S12272-001-1236-Z |
0.316 |
|
| 2008 |
Tosh DK, Choi WJ, Kim HO, Lee Y, Pal S, Hou X, Choi J, Choi S, Jeong LS. Stereoselective synthesis and conformational study of novel 2',3'-Didehydro-2',3'-dideoxy-4'-selenonucleosides. The Journal of Organic Chemistry. 73: 4259-62. PMID 18454552 DOI: 10.1021/Jo8003277 |
0.464 |
|
| 2008 |
Chun MW, Choi SW, Kang TK, Choi WJ, Kim HO, Gao ZG, Jacobson KA, Jeong LS. Synthesis of 3'-acetamidoadenosine derivatives as potential A3 adenosine receptor agonists. Nucleosides, Nucleotides & Nucleic Acids. 27: 408-20. PMID 18404574 DOI: 10.1080/15257770801944436 |
0.611 |
|
| 2008 |
Kim SJ, Min HY, Chung HJ, Park EJ, Hong JY, Kang YJ, Shin DH, Jeong LS, Lee SK. Inhibition of cell proliferation through cell cycle arrest and apoptosis by thio-Cl-IB-MECA, a novel A3 adenosine receptor agonist, in human lung cancer cells. Cancer Letters. 264: 309-15. PMID 18321638 DOI: 10.1016/J.Canlet.2008.01.037 |
0.409 |
|
| 2008 |
Jeong LS, Lee HW, Kim HO, Tosh DK, Pal S, Choi WJ, Gao ZG, Patel AR, Williams W, Jacobson KA, Kim HD. Structure-activity relationships of 2-chloro-N6-substituted-4'-thioadenosine-5'-N,N-dialkyluronamides as human A3 adenosine receptor antagonists. Bioorganic & Medicinal Chemistry Letters. 18: 1612-6. PMID 18255292 DOI: 10.1016/J.Bmcl.2008.01.070 |
0.523 |
|
| 2008 |
Jeong LS, Tosh DK, Kim HO, Wang T, Hou X, Yun HS, Kwon Y, Lee SK, Choi J, Zhao LX. First synthesis of 4'-selenonucleosides showing unusual Southern conformation. Organic Letters. 10: 209-12. PMID 18088134 DOI: 10.1021/Ol7025558 |
0.32 |
|
| 2008 |
Lee GE, Joshi BV, Chen W, Jeong LS, Moon HR, Jacobson KA, Kim YC. Synthesis and structure-activity relationship studies of tyrosine-based antagonists at the human P2X7 receptor. Bioorganic & Medicinal Chemistry Letters. 18: 571-5. PMID 18078749 DOI: 10.1016/J.Bmcl.2007.11.077 |
0.568 |
|
| 2008 |
Park A, Kim KR, Lee H, Kang J, Kim WH, Chun P, Ahmad P, Jeong LS, Moon HR. Design and Synthesis of 5''-Iodoneplanocin A and Its Analogues as Potential S-Adenosylhomocysteine Hydrolase Inhibitor Bulletin of the Korean Chemical Society. 29: 2487-2490. DOI: 10.5012/Bkcs.2008.29.12.2487 |
0.385 |
|
| 2008 |
Kim AY, Kim HO, Kim MJ, Chun MW, Lee KM, Jacobson KA, Jeong LS. ChemInform Abstract: Synthesis of 3′-(Ureido)adenosine Derivatives and Their High Binding Affinity at the Mutant A3 Adenosine Receptor Cheminform. 39. DOI: 10.1002/CHIN.200829254 |
0.538 |
|
| 2008 |
Jeong LS, et al. ea. ChemInform Abstract: Design, Synthesis, and Antitumor Activity of 4′-Thionucleosides as Potent and Selective Agonists at the Human A3Adenosine Receptor Cheminform. 39. DOI: 10.1002/CHIN.200813256 |
0.328 |
|
| 2008 |
Jeong LS, Gunaga P, Kim HO, Tosh DK, Lee HW, Choe SA, Moon HR, Gao Z, Jacobson KA, Chun MW. ChemInform Abstract: Stereoselective Synthesis of 1′-Functionalized-4′-thionucleosides Cheminform. 39. DOI: 10.1002/CHIN.200811260 |
0.393 |
|
| 2008 |
Jeong LS, Choe SA, Kim AY, Kim HO, Gao Z, Jacobson KA, Chun MW, Moon HR. ChemInform Abstract: Synthesis of N6-Substituted 3′-Ureidoadenosine Derivatives as Highly Potent Agonists at the Mutant A3Adenosine Receptor Cheminform. 39. DOI: 10.1002/CHIN.200811239 |
0.509 |
|
| 2007 |
Chun MW, Lee HW, Kim JH, Kim HO, Lee KM, Pal S, Moon HR, Jeong LS. Stereoselective synthesis of homo-apioneplanocin A as potential inhibitor of S-adenosylhomocysteine hydrolase. Nucleosides, Nucleotides & Nucleic Acids. 26: 729-32. PMID 18066890 DOI: 10.1080/15257770701493559 |
0.36 |
|
| 2007 |
Jeong LS, Lee JA, Moon HR, Kim HO, Lee KM, Lee HJ, Chun MW. Asymmetric synthesis of novel apio carbocyclic nucleoside analogues as potential antiviral and antitumor agent. Nucleosides, Nucleotides & Nucleic Acids. 26: 721-4. PMID 18066888 DOI: 10.1080/15257770701493237 |
0.348 |
|
| 2007 |
Jeong LS, Choe SA, Kim AY, Kim HO, Gao ZG, Jacobson KA, Chun MW, Moon HR. Synthesis of N6-substituted 3'-ureidoadenosine derivatives as highly potent agonists at the mutant A3 adenosine receptor. Nucleosides, Nucleotides & Nucleic Acids. 26: 717-9. PMID 18066887 DOI: 10.1080/15257770701493161 |
0.616 |
|
| 2007 |
Jeong LS, Zhao LX, Choi WJ, Pal S, Park YH, Lee SK, Chun MW, Lee YB, Ahn CH, Moon HR. Synthesis and antitumor activity of fluorocyclopentenyl-pyrimidines. Nucleosides, Nucleotides & Nucleic Acids. 26: 713-6. PMID 18066886 DOI: 10.1080/15257770701490852 |
0.389 |
|
| 2007 |
Moon HR, Park AY, Kim KR, Chun MW, Jeong LS. Asymmetric synthesis and biological activity of L-bicyclocarba-d4T. Nucleosides, Nucleotides & Nucleic Acids. 26: 1653-7. PMID 18066846 DOI: 10.1080/15257770701615599 |
0.375 |
|
| 2007 |
Jeong LS, Lee HW, Kim HO, Jung JY, Gunaga P, Lee SK, Lee EJ, Chun MW, Gao ZG, Jacobson KA, Moon HR. Design, synthesis, and anti-tumor activity of 4'-thionucleosides as potent and selective agonists at the human A3 adenosine receptor. Nucleosides, Nucleotides & Nucleic Acids. 26: 1565-8. PMID 18066827 DOI: 10.1080/15257770701547107 |
0.618 |
|
| 2007 |
Jeong LS, Lee JA, Kim HO, Tosh DK, Moon HR, Lee SJ, Lee KM, Sheen YY, Chun MW. Asymmetric synthesis of cyclopropyl-fused 2'-C-methylcarbanucleosides as potential anti-HCV agents. Nucleosides, Nucleotides & Nucleic Acids. 26: 1021-4. PMID 18058529 DOI: 10.1080/15257770701508612 |
0.323 |
|
| 2007 |
Jeong LS, Gunaga P, Kim HO, Tosh DK, Lee HW, Choe SA, Moon HR, Gao ZG, Jacobson KA, Chun MW. Stereoselective synthesis of 1'-functionalized-4'-thionucleosides. Nucleosides, Nucleotides & Nucleic Acids. 26: 1011-4. PMID 18058527 DOI: 10.1080/15257770701508588 |
0.474 |
|
| 2007 |
Park AY, Moon HR, Kim KR, Chun MW, Jeong LS. Asymmetric synthesis of novel pseudo-D-vinylcyclopropyl nucleosides bearing quaternary carbon as potential anti-herpesvirus agent. Nucleosides, Nucleotides & Nucleic Acids. 26: 1001-4. PMID 18058525 DOI: 10.1080/15257770701508232 |
0.358 |
|
| 2007 |
Moon HR, Park AY, Kim KR, Chun MW, Jeong LS. Synthesis of enantiopure pseudo-L-vinylcyclopropyl nucleosides bearing quaternary carbon as potential anti-herpesvirus agent. Nucleosides, Nucleotides & Nucleic Acids. 26: 975-8. PMID 18058520 DOI: 10.1080/15257770701508372 |
0.361 |
|
| 2007 |
Kim KR, Park AY, Moon HR, Chun MW, Jeong LS. Design, enantiopure synthesis, and biological evaluation of novel iso-D-2',3'-dideoxy-3'-fluorothianucleoside derivatives as a bioisostere of lamivudine. Nucleosides, Nucleotides & Nucleic Acids. 26: 911-5. PMID 18058507 DOI: 10.1080/15257770701506426 |
0.386 |
|
| 2007 |
Hou X, Lee HW, Tosh DK, Zhao LX, Jeong LS. Alternative and improved syntheses of highly potent and selective A3 adenosine receptor agonists, Cl-IB-MECA and thio-Cl-IB-MECA. Archives of Pharmacal Research. 30: 1205-9. PMID 18038898 DOI: 10.1007/Bf02980260 |
0.471 |
|
| 2007 |
Pugliese AM, Coppi E, Volpini R, Cristalli G, Corradetti R, Jeong LS, Jacobson KA, Pedata F. Role of adenosine A3 receptors on CA1 hippocampal neurotransmission during oxygen-glucose deprivation episodes of different duration. Biochemical Pharmacology. 74: 768-79. PMID 17626785 DOI: 10.1016/J.Bcp.2007.06.003 |
0.556 |
|
| 2007 |
Wang T, Lee HJ, Tosh DK, Kim HO, Pal S, Choi S, Lee Y, Moon HR, Zhao LX, Lee KM, Jeong LS. Design, synthesis, and molecular modeling studies of 5'-deoxy-5'-ureidoadenosine: 5'-ureido group as multiple hydrogen bonding donor in the active site of S-adenosylhomocysteine hydrolase. Bioorganic & Medicinal Chemistry Letters. 17: 4456-9. PMID 17582766 DOI: 10.1016/J.Bmcl.2007.06.013 |
0.305 |
|
| 2007 |
Jeong LS, Choe SA, Gunaga P, Kim HO, Lee HW, Lee SK, Tosh DK, Patel A, Palaniappan KK, Gao ZG, Jacobson KA, Moon HR. Discovery of a new nucleoside template for human A3 adenosine receptor ligands: D-4'-thioadenosine derivatives without 4'-hydroxymethyl group as highly potent and selective antagonists. Journal of Medicinal Chemistry. 50: 3159-62. PMID 17555308 DOI: 10.1021/Jm070259T |
0.625 |
|
| 2007 |
Palaniappan KK, Gao ZG, Ivanov AA, Greaves R, Adachi H, Besada P, Kim HO, Kim AY, Choe SA, Jeong LS, Jacobson KA. Probing the binding site of the A1 adenosine receptor reengineered for orthogonal recognition by tailored nucleosides. Biochemistry. 46: 7437-48. PMID 17542617 DOI: 10.1021/Bi7001828 |
0.571 |
|
| 2007 |
Zhao LX, Yun M, Kim HO, Lee JA, Choi WJ, Lee KM, Lee SK, Lee YB, Ahn CH, Jeong LS. Design, synthesis, and anticancer activity of fluorocyclopentenyl-pyrimidines. Nucleic Acids Symposium Series (2004). 107-8. PMID 17150656 DOI: 10.1093/NASS/49.1.107 |
0.361 |
|
| 2007 |
Lee JA, Kim HO, Tosh DK, Moon HR, Kim S, Jeong LS. Stereoselective synthesis of 2'-C-methyl-cyclopropyl-fused carbanucleosides as potential anti-HCV agents. Organic Letters. 8: 5081-3. PMID 17048848 DOI: 10.1021/Ol061959F |
0.348 |
|
| 2007 |
Kim KR, Moon HR, Park AY, Chun MW, Jeong LS. Design, synthesis, and biological evaluation of novel iso-D-2',3'-dideoxy-3'-fluorothianucleoside derivatives. Bioorganic & Medicinal Chemistry. 15: 227-34. PMID 17046264 DOI: 10.1016/J.Bmc.2006.09.066 |
0.404 |
|
| 2006 |
Besada P, Mamedova LK, Palaniappan KK, Gao ZG, Joshi BV, Jeong LS, Civan MM, Jacobson KA. NUCLEOSIDE PRODRUGS OF A ADENOSINE RECEPTOR AGONISTS AND ANTAGONISTS. Collection of Czechoslovak Chemical Communications. 71: 912-928. PMID 34815583 DOI: 10.1135/cccc20060912 |
0.495 |
|
| 2006 |
Park AY, Moon HR, Kim KR, Chun MW, Jeong LS. Synthesis of novel L-N-MCd4T as a potent anti-HIV agent. Organic & Biomolecular Chemistry. 4: 4065-7. PMID 17312958 DOI: 10.1039/B612537A |
0.334 |
|
| 2006 |
Gunaga P, Kim HO, Lee HW, Tosh DK, Ryu JS, Choi S, Jeong LS. Stereoselective functionalization of the 1'-position of 4'-thionucleosides. Organic Letters. 8: 4267-70. PMID 16956203 DOI: 10.1021/Ol061548Z |
0.356 |
|
| 2006 |
Kim SK, Gao ZG, Jeong LS, Jacobson KA. Docking studies of agonists and antagonists suggest an activation pathway of the A3 adenosine receptor. Journal of Molecular Graphics & Modelling. 25: 562-77. PMID 16793299 DOI: 10.1016/J.Jmgm.2006.05.004 |
0.553 |
|
| 2006 |
Yoo BN, Kim HO, Moon HR, Seol SK, Jang SK, Lee KM, Jeong LS. Synthesis of 2-C-hydroxymethylribofuranosylpurines as potent anti-hepatitis C virus (HCV) agents. Bioorganic & Medicinal Chemistry Letters. 16: 4190-4. PMID 16781148 DOI: 10.1016/J.Bmcl.2006.05.089 |
0.335 |
|
| 2006 |
Gao ZG, Duong HT, Sonina T, Kim SK, Van Rompaey P, Van Calenbergh S, Mamedova L, Kim HO, Kim MJ, Kim AY, Liang BT, Jeong LS, Jacobson KA. Orthogonal activation of the reengineered A3 adenosine receptor (neoceptor) using tailored nucleoside agonists. Journal of Medicinal Chemistry. 49: 2689-702. PMID 16640329 DOI: 10.1021/Jm050968B |
0.585 |
|
| 2006 |
Jeong LS, Lee HW, Kim HO, Jung JY, Gao ZG, Duong HT, Rao S, Jacobson KA, Shin DH, Lee JA, Gunaga P, Lee SK, Jin DZ, Chun MW, Moon HR. Design, synthesis, and biological activity of N6-substituted-4'-thioadenosines at the human A3 adenosine receptor. Bioorganic & Medicinal Chemistry. 14: 4718-30. PMID 16603368 DOI: 10.1016/J.Bmc.2006.03.030 |
0.614 |
|
| 2006 |
Chung H, Jung JY, Cho SD, Hong KA, Kim HJ, Shin DH, Kim H, Kim HO, Shin DH, Lee HW, Jeong LS, Kong G. The antitumor effect of LJ-529, a novel agonist to A3 adenosine receptor, in both estrogen receptor-positive and estrogen receptor-negative human breast cancers. Molecular Cancer Therapeutics. 5: 685-92. PMID 16546983 DOI: 10.1158/1535-7163.Mct-05-0245 |
0.348 |
|
| 2006 |
Jeong LS, Lee HW, Jacobson KA, Kim HO, Shin DH, Lee JA, Gao ZG, Lu C, Duong HT, Gunaga P, Lee SK, Jin DZ, Chun MW, Moon HR. Structure-activity relationships of 2-chloro-N6-substituted-4'-thioadenosine-5'-uronamides as highly potent and selective agonists at the human A3 adenosine receptor. Journal of Medicinal Chemistry. 49: 273-81. PMID 16392812 DOI: 10.1021/Jm050595E |
0.594 |
|
| 2006 |
Gao ZG, Joshi BV, Klutz AM, Kim SK, Lee HW, Kim HO, Jeong LS, Jacobson KA. Conversion of A3 adenosine receptor agonists into selective antagonists by modification of the 5'-ribofuran-uronamide moiety. Bioorganic & Medicinal Chemistry Letters. 16: 596-601. PMID 16289820 DOI: 10.1016/J.Bmcl.2005.10.054 |
0.566 |
|
| 2006 |
Besada P, Mamedova LK, Palaniappan KK, Gao ZG, Joshi BV, Jeong LS, Civan MM, Jacobson KA. Nucleoside prodrugs of A3 adenosine receptor agonists and antagonists Collection of Czechoslovak Chemical Communications. 71: 912-928. DOI: 10.1135/Cccc20060912 |
0.599 |
|
| 2006 |
Kim J, Kim HO, Lee KM, Chun MW, Moon HR, Jeong LS. Asymmetric synthesis of homo-apioneplanocin A from d-ribose Tetrahedron. 62: 6339-6342. DOI: 10.1016/J.Tet.2006.04.042 |
0.359 |
|
| 2006 |
Gao Z, Joshi BV, Klutz AM, Kim S, Lee HW, Kim HO, Jeong LS, Jacobson KA. Conversion of A3 Adenosine Receptor Agonists into Selective Antagonists by Modification of the 5′-Ribofuran-uronamide Moiety. Cheminform. 37. DOI: 10.1002/CHIN.200618207 |
0.516 |
|
| 2005 |
Kim AY, Kim HO, Kim MJ, Chun MW, Lee KM, Jacobson KA, Jeong LS. Synthesis of 3'-ureidoadenosines and their high binding affinity at the mutant A3 adenosine receptor. Nucleic Acids Symposium Series (2004). 105-6. PMID 17150655 DOI: 10.1093/nass/49.1.105 |
0.53 |
|
| 2005 |
Jeong LS, Lee HW, Jacobson KA, Lee SK, Chun MW. Development of potent and selective human A3 adenosine receptor agonists. Nucleic Acids Symposium Series (2004). 31-2. PMID 17150618 DOI: 10.1093/nass/49.1.31 |
0.527 |
|
| 2005 |
Chun MW, Lee HW, Kim AY, Kim MJ, Kim HO, Gao ZG, Jacobson KA, Jeong LS. Synthesis of 3'-ureidoadenosine analogues and their binding affinity to the A3 adenosine receptor. Nucleosides, Nucleotides & Nucleic Acids. 24: 1119-21. PMID 16248104 DOI: 10.1081/Ncn-200060079 |
0.609 |
|
| 2005 |
Gunaga P, Kim HO, Kim HJ, Chun MW, Jeong LS. Stereoselective synthesis of novel thioiso dideoxy nucleosides with exocyclic methylene as potential antiviral agents. Nucleosides, Nucleotides & Nucleic Acids. 24: 1115-7. PMID 16248103 DOI: 10.1081/Ncn-200060072 |
0.486 |
|
| 2005 |
Chun MW, Kim JH, Kim MJ, Kim BR, Jeong LS. Synthesis of homo-N-nucleoside with 1,2,4-triazole-3-carboxamide. Nucleosides, Nucleotides & Nucleic Acids. 24: 979-81. PMID 16248076 DOI: 10.1081/Ncn-200059368 |
0.381 |
|
| 2005 |
Chun MW, Kim MJ, Shin JH, Jeong LS. Synthesis of 3'-deoxy-3'-C-hydroxymethyl analogues of tiazofurin and ribavirin. Nucleosides, Nucleotides & Nucleic Acids. 24: 975-7. PMID 16248075 DOI: 10.1081/Ncn-200059338 |
0.423 |
|
| 2005 |
Moon HR, Lee KM, Lee JH, Lee SK, Park SB, Chun MW, Jeong LS. Structure-activity relationship of 5'-substituted fluoro-neplanocin a analogues as potent inhibitors of S-adenosylhomocysteine hydrolase. Nucleosides, Nucleotides & Nucleic Acids. 24: 707-8. PMID 16248019 DOI: 10.1081/Ncn-200060286 |
0.393 |
|
| 2005 |
Choi WJ, Moon HR, Kim HO, Ko YM, Kim HJ, Lee JA, Lee KM, Yun MK, Shin DH, Chun MW, Sheen YY, Kim K, Jeong LS. Stereoselective synthesis of 3-hydroxymethyl-D-cyclopentenone, the versatile intermediate for the synthesis of carbocyclic nucleosides. Nucleosides, Nucleotides & Nucleic Acids. 24: 611-3. PMID 16247998 DOI: 10.1081/Ncn-200061832 |
0.412 |
|
| 2005 |
Lee HW, Shin DH, Jeong JY, Kim HO, Chun MW, Melman N, Gao ZG, Jacobson KA, Jeong LS. D-4'-thioadenosine derivatives as highly potent and selective agonists at the human A3 adenosine receptor. Nucleosides, Nucleotides & Nucleic Acids. 24: 607-9. PMID 16247997 DOI: 10.1081/NCN-200061827 |
0.562 |
|
| 2005 |
Lee EJ, Min HY, Chung HJ, Park EJ, Shin DH, Jeong LS, Lee SK. A novel adenosine analog, thio-Cl-IB-MECA, induces G0/G1 cell cycle arrest and apoptosis in human promyelocytic leukemia HL-60 cells. Biochemical Pharmacology. 70: 918-24. PMID 16051194 DOI: 10.1016/J.Bcp.2005.06.017 |
0.339 |
|
| 2005 |
Lee JA, Moon HR, Kim HO, Kim KR, Lee KM, Kim BT, Hwang KJ, Chun MW, Jacobson KA, Jeong LS. Synthesis of novel apio carbocyclic nucleoside analogues as selective a(3) adenosine receptor agonists. The Journal of Organic Chemistry. 70: 5006-13. PMID 15960499 DOI: 10.1021/Jo0503207 |
0.638 |
|
| 2005 |
Gunaga P, Moon HR, Choi WJ, Shin DH, Park JG, Jeong LS. Recent advances in 4'-thionucleosides as potential antiviral and antitumor agents. Current Medicinal Chemistry. 11: 2585-637. PMID 15544465 DOI: 10.2174/0929867043364478 |
0.311 |
|
| 2005 |
Jeong LS, Lee JA. Recent advances in the synthesis of the carbocyclic nucleosides as potential antiviral agents. Antiviral Chemistry & Chemotherapy. 15: 235-50. PMID 15535045 DOI: 10.1177/095632020401500502 |
0.383 |
|
| 2004 |
Moon HR, Lee HJ, Kim KR, Lee KM, Lee SK, Kim HO, Chun MW, Jeong LS. Synthesis of 5'-substituted fluoro-neplanocin A analogues: importance of a hydrogen bonding donor at 5'-position for the inhibitory activity of S-adenosylhomocysteine hydrolase. Bioorganic & Medicinal Chemistry Letters. 14: 5641-4. PMID 15482939 DOI: 10.1016/J.Bmcl.2004.08.047 |
0.45 |
|
| 2004 |
Jeong LS, Kim MJ, Kim HO, Gao ZG, Kim SK, Jacobson KA, Chun MW. Design and synthesis of 3'-ureidoadenosine-5'-uronamides: effects of the 3'-ureido group on binding to the A3 adenosine receptor. Bioorganic & Medicinal Chemistry Letters. 14: 4851-4. PMID 15341938 DOI: 10.1016/J.Bmcl.2004.07.042 |
0.567 |
|
| 2004 |
Kim MJ, Jeong LS, Kim JH, Shin JH, Chung SY, Lee SK, Chun MW. Synthesis and biological evaluation of novel apio nucleosides with thiazole-4-carboxamide and 1,2,4-triazole-3-carboxamide. Nucleosides, Nucleotides & Nucleic Acids. 23: 715-24. PMID 15200033 DOI: 10.1081/Ncn-120037666 |
0.398 |
|
| 2004 |
Gunaga P, Baba M, Jeong LS. Asymmetric synthesis of novel thioiso dideoxynucleosides with exocyclic methylene as potential antiviral agents. The Journal of Organic Chemistry. 69: 3208-11. PMID 15104467 DOI: 10.1021/Jo035735B |
0.367 |
|
| 2004 |
Gao ZG, Jeong LS, Moon HR, Kim HO, Choi WJ, Shin DH, Elhalem E, Comin MJ, Melman N, Mamedova L, Gross AS, Rodriguez JB, Jacobson KA. Structural determinants of efficacy at A3 adenosine receptors: modification of the ribose moiety. Biochemical Pharmacology. 67: 893-901. PMID 15104242 DOI: 10.1016/J.Bcp.2003.10.006 |
0.602 |
|
| 2004 |
Kim HO, Yoo SJ, Ahn HS, Choi WJ, Moon HR, Lee KM, Chun MW, Jeong LS. Synthesis of fluorinated cyclopentenyladenine as potent inhibitor of S-adenosylhomocysteine hydrolase. Bioorganic & Medicinal Chemistry Letters. 14: 2091-3. PMID 15080985 DOI: 10.1016/J.Bmcl.2004.02.039 |
0.399 |
|
| 2004 |
Kim HO, Baek HW, Moon HR, Kim DK, Chun MW, Jeong LS. Synthesis and biological evaluation of novel tert-azido or tert-amino substituted penciclovir analogs. Organic & Biomolecular Chemistry. 2: 1164-8. PMID 15064793 DOI: 10.1039/B401100G |
0.406 |
|
| 2004 |
Choi WJ, Moon HR, Kim HO, Yoo BN, Lee JA, Shin DH, Jeong LS. Preparative and stereoselective synthesis of the versatile intermediate for carbocyclic nucleosides: effects of the bulky protecting groups to enforce facial selectivity. The Journal of Organic Chemistry. 69: 2634-6. PMID 15049678 DOI: 10.1021/Jo0356762 |
0.376 |
|
| 2004 |
Jin DZ, Kwon SH, Moon HR, Gunaga P, Kim HO, Kim DK, Chun MW, Jeong LS. Synthesis of D- and L-apio nucleoside analogues with 2'-hydroxyl group as potential anti-HIV agents. Bioorganic & Medicinal Chemistry. 12: 1101-9. PMID 14980622 DOI: 10.1016/J.Bmc.2003.12.002 |
0.386 |
|
| 2004 |
Kim HO, Park JG, Moon HR, Gunaga P, Lim MH, Chun MW, Jacobson KA, Kim H, Jeong LS. Design and Synthesis of A3 Adenosine Receptor Ligands, 2′-Fluoro Analogues of Cl-IB-MECA Cheminform. 35. DOI: 10.1002/CHIN.200405189 |
0.528 |
|
| 2004 |
Kim HO, Lim MH, Park JG, Moon HR, Jacobson KA, Kim H, Chun MW, Jeong LS. Design and Synthesis of A3 Adenosine Receptor Ligands, 3′-Fluoro Analogues of Cl-IB-MECA Cheminform. 35. DOI: 10.1002/CHIN.200405188 |
0.528 |
|
| 2003 |
Liang CW, Kim MJ, Jeong LS, Chun MW. Synthesis of 2-(3'-azido- and 3'-amino-3'-deoxy-beta-D-ribofuranosyl)thiazole-4-carboxamide. Nucleosides, Nucleotides & Nucleic Acids. 22: 2039-48. PMID 14680026 DOI: 10.1081/Ncn-120026405 |
0.378 |
|
| 2003 |
Moon HR, Kwon SH, Lee JA, Yoo BN, Kim HO, Chun MW, Kim HD, Kim JH, Jeong LS. Design, synthesis, and in vitro evaluation of APIO analogue of neplanocin A. Nucleosides, Nucleotides & Nucleic Acids. 22: 1475-7. PMID 14565446 DOI: 10.1081/Ncn-120023014 |
0.41 |
|
| 2003 |
Park JH, Choi MH, Jeong LS, Chun MW, Kim HD. Synthesis of [1'-fluoro-2',2'-bis-(hydroxymethyl)cyclopropylmethyl]purines as antiviral agents. Nucleosides, Nucleotides & Nucleic Acids. 22: 955-7. PMID 14565320 DOI: 10.1081/Ncn-120022694 |
0.364 |
|
| 2003 |
Kim HO, Park JG, Moon HR, Gunaga P, Lim MH, Chun MW, Jacobson KA, Kim HD, Jeong LS. Design and synthesis of A3 adenosine receptor ligands, 2'-fluoro analogues of Cl-IB-MECA. Nucleosides, Nucleotides & Nucleic Acids. 22: 927-30. PMID 14565313 DOI: 10.1081/NCN-120022687 |
0.559 |
|
| 2003 |
Kim HO, Lim MH, Park JG, Moon HR, Jacobson KA, Kim HD, Chun MW, Jeong LS. Design and synthesis of A3 adenosine receptor ligands, 3'-fluoro analogues of Cl-IB-MECA. Nucleosides, Nucleotides & Nucleic Acids. 22: 923-5. PMID 14565312 DOI: 10.1081/Ncn-120022701 |
0.613 |
|
| 2003 |
Jeong LS, Park JG, Choi WJ, Moon HR, Lee KM, Kim HO, Kim HD, Chun MW, Park HY, Kim K, Sheen YY. Synthesis of halogenated 9-(dihydroxycyclopent-4'-enyl) adenines and their inhibitory activities against S-adenosylhomocysteine hydrolase. Nucleosides, Nucleotides & Nucleic Acids. 22: 919-21. PMID 14565311 DOI: 10.1081/Ncn-120022686 |
0.417 |
|
| 2003 |
Chun MW, Kim MJ, Kim HO, Kim HD, Kim JH, Moon HR, Jeong LS. Synthesis of 5-azacytidine nucleosides with rigid sugar moiety as potential antitumor agents. Nucleosides, Nucleotides & Nucleic Acids. 22: 915-7. PMID 14565310 DOI: 10.1081/Ncn-120022685 |
0.316 |
|
| 2003 |
Chun MW, Kim MJ, Kim HO, Moon HR, Kim HD, Kim JH, Jeong LS. Synthesis and biological evaluation of pyrimidine nucleosides fused with 3',4'-tetrahydrofuran ring. Nucleosides, Nucleotides & Nucleic Acids. 22: 719-21. PMID 14565262 DOI: 10.1081/Ncn-120022618 |
0.412 |
|
| 2003 |
Park JH, Lee YR, Chun MW, Jeong LS, Lee CK, Kim HD. Synthesis of (Z)-(1-fluoro-2-hydroxymethylcyclopropylmethyl)purines. Nucleosides, Nucleotides & Nucleic Acids. 22: 659-61. PMID 14565247 DOI: 10.1081/Ncn-120022605 |
0.333 |
|
| 2003 |
Jeong LS, Moon HR, Park JG, Shin DH, Choi WJ, Lee KM, Kim HO, Chun MW, Kim HD, Kim JH. Synthesis and biological evaluation of halo-neplanocin A as novel mechanism-based inhibitors of S-adenosylhomocysteine hydrolase. Nucleosides, Nucleotides & Nucleic Acids. 22: 589-92. PMID 14565234 DOI: 10.1081/Ncn-120021961 |
0.345 |
|
| 2003 |
Chun MW, Lim MH, Moon HR, Kim HO, Jacobson KA, Jeong LS. Synthesis of 3'-fluoro analogue of Cl-IB-MECA as adenosine A3 receptor ligand. Nucleic Acids Research. Supplement (2001). 19-20. PMID 14510359 DOI: 10.1093/nass/3.1.19 |
0.542 |
|
| 2003 |
Lee JA, Yoo BN, Choi WJ, Moon HR, Jeong LS. Synthesis of apio analogues of neplanocin A as potential inhibitors of S-adenosylhomocysteine hydrolase. Nucleic Acids Research. Supplement (2001). 15-6. PMID 14510357 DOI: 10.1093/nass/3.1.15 |
0.318 |
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| 2003 |
Kim MJ, Kim HO, Kim HD, Kim JH, Jeong LS, Chun MW. Synthesis and biological evaluation of thymine nucleosides fused with 3',4'-tetrahydrofuran ring. Bioorganic & Medicinal Chemistry Letters. 13: 3499-501. PMID 14505657 DOI: 10.1016/S0960-894X(03)00730-3 |
0.384 |
|
| 2003 |
Jeong LS, Jin DZ, Kim HO, Shin DH, Moon HR, Gunaga P, Chun MW, Kim YC, Melman N, Gao ZG, Jacobson KA. N6-substituted D-4'-thioadenosine-5'-methyluronamides: potent and selective agonists at the human A3 adenosine receptor. Journal of Medicinal Chemistry. 46: 3775-7. PMID 12930138 DOI: 10.1021/Jm034098E |
0.591 |
|
| 2003 |
Lim MH, Kim HO, Moon HR, Lee SJ, Chun MW, Gao ZG, Melman N, Jacobson KA, Kim JH, Jeong LS. Design, synthesis and binding affinity of 3'-fluoro analogues of Cl-IB-MECA as adenosine A3 receptor ligands. Bioorganic & Medicinal Chemistry Letters. 13: 817-20. PMID 12617898 DOI: 10.1016/S0960-894X(03)00027-1 |
0.596 |
|
| 2003 |
Jeong LS, Yoo SJ, Lee KM, Koo MJ, Choi WJ, Kim HO, Moon HR, Lee MY, Park JG, Lee SK, Chun MW. Design, synthesis, and biological evaluation of fluoroneplanocin A as the novel mechanism-based inhibitor of S-adenosylhomocysteine hydrolase. Journal of Medicinal Chemistry. 46: 201-3. PMID 12519056 DOI: 10.1021/Jm025557Z |
0.362 |
|
| 2003 |
Moon HR, Kim HO, Jeong LS. Synthesis of 2′,3′-Didehydro-2′,3′-dideoxy-2′-fluoro Apionucleosides as Potential Antiviral Agents. Cheminform. 34. DOI: 10.1039/B203126D |
0.339 |
|
| 2003 |
Lim MH, Kim HO, Moon HR, Lee SJ, Chun MW, Gao Z, Melman N, Jacobson KA, Kim JH, Jeong LS. Corrigendum to ‘Design, Synthesis and Binding Affinity of 3′-Fluoro Analogues of C1-IB-MECA as Adenosine A3 Receptor Ligands’[Bioorg. Med. Chem. Lett. 13 (2003) 817]† Bioorganic & Medicinal Chemistry Letters. 13: 2087. DOI: 10.1016/S0960-894X(03)00332-9 |
0.599 |
|
| 2002 |
Moon HR, Kim HO, Lee KM, Chun MW, Kim JH, Jeong LS. Stereoselective synthesis of a novel apio analogue of neplanocin A as potential S-adenosylhomocysteine hydrolase inhibitor. Organic Letters. 4: 3501-3. PMID 12323054 DOI: 10.1021/Ol026624M |
0.372 |
|
| 2002 |
Kim HO, Park YH, Moon HR, Jeong LS. Synthesis and biological evaluation of novel D-2'-azido-2',3'-dideoxyarabinofuranosyl-4'-thiopyrimidines and purines. Bioorganic & Medicinal Chemistry Letters. 12: 2403-6. PMID 12161143 DOI: 10.1016/S0960-894X(02)00394-3 |
0.386 |
|
| 2002 |
Moon HR, Kim HO, Lee SK, Choi WJ, Chun MW, Jeong LS. Synthesis and biological evaluation of novel thioapio dideoxynucleosides. Bioorganic & Medicinal Chemistry. 10: 1499-507. PMID 11886812 DOI: 10.1016/S0968-0896(01)00417-5 |
0.407 |
|
| 2002 |
Lim MH, Kim HO, Moon HR, Chun MW, Jeong LS. Synthesis of novel D-2'-deoxy-2'-C-difluoromethylene-4'-thiocytidine as a potential antitumor agent. Organic Letters. 4: 529-31. PMID 11843583 DOI: 10.1021/Ol017112V |
0.34 |
|
| 2002 |
Heo YH, Kim S, Park JE, Jeong LS, Lee SK. Induction of quinone reductase activity by stilbene analogs in mouse Hepa 1c1c7 cells. Archives of Pharmacal Research. 24: 597-600. PMID 11794542 DOI: 10.1007/Bf02975172 |
0.339 |
|
| 2002 |
Yoo SJ, Kim HO, Lim Y, Kim J, Jeong LS. Synthesis of novel (2R,4R)- and (2S,4S)-iso dideoxynucleosides with exocyclic methylene as potential antiviral agents. Bioorganic & Medicinal Chemistry. 10: 215-26. PMID 11738624 DOI: 10.1016/S0968-0896(01)00266-8 |
0.353 |
|
| 2002 |
Moon HR, Choi WJ, Kim HO, Jeong LS. Improved and alternative synthesis of d- and l-cyclopentenone derivatives, the versatile intermediates for the synthesis of carbocyclic nucleosides Tetrahedron: Asymmetry. 13: 1189-1193. DOI: 10.1016/S0957-4166(02)00316-6 |
0.406 |
|
| 2002 |
Choi WJ, Ahn HS, Kim HO, Kim S, Chun MW, Jeong LS. Stereoselective synthesis of amino-substituted apio dideoxynucleosides through a distant neighboring group effect Tetrahedron Letters. 43: 6241-6243. DOI: 10.1016/S0040-4039(02)01295-9 |
0.367 |
|
| 2001 |
Chun MW, Kim MJ, Jo UH, Kim JH, Kim HD, Jeong LS. Synthesis of novel D- and L-3'-deoxy-3'-C-hydroxymethyl nucleoside with exocyclic methylene as potential ribonucleotide reductase inhibitor. Nucleosides, Nucleotides & Nucleic Acids. 20: 703-6. PMID 11563096 DOI: 10.1081/Ncn-100002355 |
0.355 |
|
| 2001 |
Chun MW, Kim MJ, Jo UH, Kim JH, Kim HD, Jeong LS. Synthesis of novel 3'-deoxy-3'-C-hydroxymethyl nucleosides with conformationally rigid sugar moiety as potential antiviral agents. Nucleosides, Nucleotides & Nucleic Acids. 20: 699-702. PMID 11563095 DOI: 10.1081/Ncn-100002354 |
0.399 |
|
| 2001 |
Choi MH, Lee CK, Jeong LS, Chun MW, Kim HD. Novel nucleosides with vinyl fluoride or vinyl bromide moiety as open-chain analogs of neplanocin A. Nucleosides, Nucleotides & Nucleic Acids. 20: 681-4. PMID 11563091 DOI: 10.1081/Ncn-100002350 |
0.348 |
|
| 2001 |
Lee YR, Park JH, Jeon R, Jeong LS, Chun MW, Kim HD. Design and synthesis of novel fluorocyclopropanoid nucleosides. Nucleosides, Nucleotides & Nucleic Acids. 20: 677-9. PMID 11563090 DOI: 10.1081/Ncn-100002349 |
0.333 |
|
| 2001 |
Jeong LS, Kim YH, Kim HO, Yoo SJ, Park YH, Yeon SH, Chun MW, Kim HD. Synthesis and antiviral activity of D- and L-2'-azido-2',3'-dideoxy-4'-thiopyrimidine and purine nucleosides. Nucleosides, Nucleotides & Nucleic Acids. 20: 665-8. PMID 11563087 DOI: 10.1081/Ncn-100002346 |
0.348 |
|
| 2001 |
Jeong LS, Moon HR, Hong JH, Yoo SJ, Choi WJ, Kim HO, Ahn HS, Baek HW, Chun MW, Kim HD, Kim J, Choi JR. Structure-activity relationships of apio nucleosides as potential antiviral agents. Nucleosides, Nucleotides & Nucleic Acids. 20: 657-60. PMID 11563085 DOI: 10.1081/Ncn-100002344 |
0.361 |
|
| 2001 |
Choi WJ, Park JG, Yoo SJ, Kim HO, Moon HR, Chun MW, Jung YH, Jeong LS. Syntheses of D- and L-cyclopentenone derivatives using ring-closing metathesis: versatile intermediates for the synthesis of D- and L-carbocyclic nucleosides. The Journal of Organic Chemistry. 66: 6490-4. PMID 11559205 DOI: 10.1021/Jo015733W |
0.359 |
|
| 2001 |
Hong JH, Kim HO, Moon HR, Jeong LS. Synthesis and antiviral activity of fluoro-substituted apio dideoxynucleosides. Archives of Pharmacal Research. 24: 95-99. PMID 11339639 DOI: 10.1007/Bf02976474 |
0.34 |
|
| 2001 |
Jeong LS, Kim HO, Moon HR, Hong JH, Yoo SJ, Choi WJ, Chun MW, Lee CK. Syntheses and structure--activity relationships of novel apio and thioapio dideoxydidehydronucleosides as anti-HCMV agents. Journal of Medicinal Chemistry. 44: 806-13. PMID 11262090 DOI: 10.1021/Jm000342F |
0.441 |
|
| 2001 |
Kim HO, Kim YH, Suh H, Jeong LS. Synthesis and antiviral activity of novel D- and L-2'-azido-2',3'-dideoxyribofuranosyl-4'-thiopyrimidines and purines. Bioorganic & Medicinal Chemistry Letters. 11: 599-603. PMID 11229780 DOI: 10.1016/S0960-894X(01)00006-3 |
0.407 |
|
| 2000 |
Shin DH, Lee HW, Park SS, Kim JH, Jeong LS, Chun MW. Synthesis of (-)-neplanocin A analogues as potential antiviral agents. Archives of Pharmacal Research. 23: 302-9. PMID 10976574 DOI: 10.1007/Bf02975438 |
0.448 |
|
| 2000 |
Kim HO, Jeong LS, Lee SN, Yoo SJ, Moon HR, Kim KS, Chun MW. A highly efficient synthesis of L-β-2′-deoxy-4′-thio-1′-purine nucleosides as potential antiviral agents Journal of the Chemical Society-Perkin Transactions 1. 1327-1329. DOI: 10.1039/B001240H |
0.33 |
|
| 1999 |
Moon HR, Kim HO, Chun MW, Jeong LS, Marquez VE. Synthesis of Cyclopropyl-Fused Carbocyclic Nucleosides via the Regioselective Opening of Cyclic Sulfites. The Journal of Organic Chemistry. 64: 4733-4741. PMID 11674546 DOI: 10.1021/Jo990010M |
0.511 |
|
| 1999 |
Jeong LS, Lee JH, Jung K, Moon HR, Kim K, Lim H. Synthesis and hybridization property of sugar and phosphate linkage modified oligonucleotides. Bioorganic & Medicinal Chemistry. 7: 1467-1473. PMID 10465421 DOI: 10.1016/S0968-0896(99)00061-9 |
0.36 |
|
| 1999 |
Jeong LS, Yoo SJ, Moon HR, Chun MW, Lee CK. Synthesis and antiviral activity of D- and L-isodideoxy nucleosides with exocyclic-methylene. Nucleosides & Nucleotides. 18: 655-6. PMID 10432660 DOI: 10.1080/15257779908041531 |
0.338 |
|
| 1999 |
Chun MW, Choi SP, Kim MJ, Bae CJ, Moon HR, Kim HD, Jeong LS. Synthesis and antiviral activities of 1,3-oxathiolanyl nucleosides with 5-hydroxymethyl substituent Nucleosides and Nucleotides. 18: 615-616. PMID 10432654 DOI: 10.1080/15257779908041515 |
0.401 |
|
| 1999 |
Jeong LS, Moon HR, Yoo SJ, Lee SN, Kim HD, Chun MW. Synthesis and antiviral activity of L-2'-deoxy-2'-up-fluoro-4'-thionucleosides. Nucleosides & Nucleotides. 18: 571-2. PMID 10432648 DOI: 10.1080/15257779908041497 |
0.337 |
|
| 1999 |
Chun MW, Shin DH, Song SY, Lee YH, Lee CH, Jeong LS, Lee SK. Synthesis of L-Sangivamycin and Toyocamycin Analogues and Their Inhibitory Activities of SER/THR Protein Kinases Nucleosides and Nucleotides. 18: 617-618. DOI: 10.1080/15257779908041516 |
0.311 |
|
| 1998 |
Jeong LS, Lee JE, Kim HO, Chun MW. Synthesis and antiviral activity of 2'-fluorohexopyranosyl nucleosides. Archives of Pharmacal Research. 21: 338-43. PMID 9875454 DOI: 10.1007/Bf02975298 |
0.452 |
|
| 1998 |
Jeong LS, Yoo SJ. Synthesis and antiviral activity of novel isodideoxy nucleosides with exocyclic methylene Bioorganic & Medicinal Chemistry Letters. 8: 847-852. PMID 9871553 DOI: 10.1016/S0960-894X(98)00122-X |
0.376 |
|
| 1998 |
Jeong LS, Yoo SJ, Moon HR, Kim YH, Chun MW. Participation of sulfur occurred during the Mitsunobu reaction: synthesis of novel isodideoxythionucleosides Journal of the Chemical Society-Perkin Transactions 1. 3325-3326. DOI: 10.1039/A806562D |
0.329 |
|
| 1998 |
Jeong LS, Moon HR, Choi YJ, Chun MW, Kim HO. A Short and Efficient Synthesis ofl-Thioarabinose Derivative: A Versatile Synthon for the Synthesis ofl-2‘-Deoxy- 2‘,2‘-disubstituted-4‘-thionucleosides The Journal of Organic Chemistry. 63: 4821-4825. DOI: 10.1021/Jo980196+ |
0.362 |
|
| 1998 |
Jeong LS, Moon HR, Yoo SJ, Lee SN, Chun MW, Lim Y. Ring contraction and rearrangement of 4-thiofuranose derivatives observed during DAST fluorination in the synthesis of l-2′-“up”-fluoro-4′-thiothymidine Tetrahedron Letters. 39: 5201-5204. DOI: 10.1016/S0040-4039(98)01021-1 |
0.353 |
|
| 1997 |
Jeong LS, Bae M, Chun MW, Marquez VE. Synthesis and Anti-HIV Activity of Carbocyclic Ring-Enlarged 4′,1′a-Methano Oxetanocin Analogues Nucleosides and Nucleotides. 16: 1059-1062. DOI: 10.1080/07328319708006132 |
0.394 |
|
| 1997 |
Chun MW, Shin DH, Moon HR, Lee J, Park H, Jeong LS. Syntheses and antiviral activities of 1,3-dioxolanyl-, 1,3-oxathiolanyl- and 1,3-dithiolanylnucleosides with 2-hydroxymethyl substituents Bioorganic & Medicinal Chemistry Letters. 7: 1475-1480. DOI: 10.1016/S0960-894X(97)00250-3 |
0.377 |
|
| 1996 |
Jeong LS, Marquez VE. Use of a cyclic sulfite as an epoxide surrogate in the regioselective synthesis of a carbocyclic ring-enlarged 4′,1′a-methano oxetanocin analogue Tetrahedron Letters. 37: 2353-2356. DOI: 10.1016/0040-4039(96)00289-4 |
0.471 |
|
| 1995 |
Marquez V, Jeong L, Nicklaus M, George C. Synthesis and Biological Activity of Sugar-Fluorinated 2',3'-dideoxy-4'-thioribofuranosyl Nucleosides Nucleosides, Nucleotides and Nucleic Acids. 14: 555-558. DOI: 10.1080/15257779508012426 |
0.361 |
|
| 1995 |
Jeong LS, Marquez VE. First Synthesis of a Dideoxydifluoro Nucleoside with a .beta.-D-lyxo Configuration. An Unprecedented Effect of the cis-Fluorines on the Reactivity of the Aglycon The Journal of Organic Chemistry. 60: 4276-4279. DOI: 10.1021/Jo00118A054 |
0.309 |
|
| 1994 |
Jeong LS, Lim BB, Marquez VE. Synthesis of a 2,3-dideoxy-2,3-difluorofuranose with the D-lyxo configuration. An intramolecular rearrangement of methyl 5-O-benzoyl-2,3-dideoxy-2,3-difluoro-D-lyxofuranoside observed during the attempted synthesis of 1-(2,3-dideoxy-2,3-difluoro-beta-D-lyxofuranosyl)thymine. Carbohydrate Research. 262: 103-14. PMID 7954518 DOI: 10.1016/0008-6215(94)84007-5 |
0.365 |
|
| 1994 |
Jeong LS, Nicklaus MC, George C, Marquez VE. Facile fluorination of deoxy-4′-thiopyrimidine nucleosides with “down” hydroxyl groups. Retention of configuration after fluoride opening of the quaternized N3-MEM anhydronucleosides Tetrahedron Letters. 35: 7573-7576. DOI: 10.1016/S0040-4039(00)78346-8 |
0.304 |
|
| 1992 |
Kim HO, Ahn SK, Alves AJ, Beach JW, Jeong LS, Choi BG, Van Roey P, Schinazi RF, Chu CK. Asymmetric synthesis of 1,3-dioxolane-pyrimidine nucleosides and their anti-HIV activity. Journal of Medicinal Chemistry. 35: 1987-95. PMID 1597854 DOI: 10.1021/Jm00089A007 |
0.346 |
|
| 1992 |
Beach JW, Kim HO, Jeong LS, Nampalli S, Islam Q, Ahn SK, Babu JR, Chu CK. A highly stereoselective synthesis of anti-HIV 2',3'-dideoxy- and 2',3'-didehydro-2',3'-dideoxynucleosides The Journal of Organic Chemistry. 57: 3887-3894. DOI: 10.1021/Jo00040A031 |
0.348 |
|
| 1992 |
Beach JW, Jeong LS, Alves AJ, Pohl D, Kim HO, Chang CN, Doong SL, Schinazi RF, Cheng YC, Chu CK. Synthesis of enantiomerically pure (2'R,5'S)-(-)-1-(2-hydroxymethyloxathiolan-5-yl)cytosine as a potent antiviral agent against hepatitis B virus (HBV) and human immunodeficiency virus (HIV) The Journal of Organic Chemistry. 57: 2217-2219. DOI: 10.1021/Jo00034A006 |
0.34 |
|
| 1991 |
Chu CK, Beach JW, Jeong LS, Choi BG, Comer FI, Alves AJ, Schinazi RF. Enantiomeric synthesis of (+)-BCH-189 [(+)-(2S,5R)-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine] from D-mannose and its anti-HIV activity The Journal of Organic Chemistry. 56: 6503-6505. DOI: 10.1021/Jo00023A010 |
0.334 |
|
| 1990 |
Chu CK, Ullas GV, Jeong LS, Ahn SK, Doboszewski B, Lin ZX, Beach JW, Schinazi RF. Synthesis and structure-activity relationships of 6-substituted 2',3'-dideoxypurine nucleosides as potential anti-human immunodeficiency virus agents. Journal of Medicinal Chemistry. 33: 1553-61. PMID 2342052 DOI: 10.1021/JM00168A006 |
0.354 |
|
| 1990 |
Chu CK, Babu JR, Beach JW, Ahn SK, Huang H, Jeong LS, Lee SJ. A highly stereoselective glycosylation of 2-(phenylselenenyl)-2,3-dideoxyribose derivative with thymine: synthesis of 3'-deoxy-2',3'-didehydrothymidine and 3'-deoxythymidine The Journal of Organic Chemistry. 55: 1418-1420. DOI: 10.1021/Jo00292A006 |
0.397 |
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