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Chengran Yang - Publications

Affiliations: 
Washington University School of Medicine, St. Louis, MO, United States 
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25 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Wang C, Yang C, Western D, Ali M, Wang Y, Phuah CL, Budde J, Wang L, Gorijala P, Timsina J, Ruiz A, Pastor P, Fernandez MV, Panyard DJ, Engelman CD, et al. Genetic architecture of cerebrospinal fluid and brain metabolite levels and the genetic colocalization of metabolites with human traits. Nature Genetics. PMID 39528826 DOI: 10.1038/s41588-024-01973-7  0.791
2024 Western D, Timsina J, Wang L, Wang C, Yang C, Phillips B, Wang Y, Liu M, Ali M, Beric A, Gorijala P, Kohlfeld P, Budde J, Levey AI, Morris JC, et al. Proteogenomic analysis of human cerebrospinal fluid identifies neurologically relevant regulation and implicates causal proteins for Alzheimer's disease. Nature Genetics. PMID 39528825 DOI: 10.1038/s41588-024-01972-8  0.818
2024 Anastasi F, Genius P, Rodriguez-Fernandez B, Yang C, Gorijala P, Timsina J, Hernández-Villamizar F, Lorenzini L, Del Campo M, Sanchez-Benavides G, Minguillon C, Navarro A, Cruchaga C, Suárez-Calvet M, Vilor-Tejedor N. Polygenic proxies of age-related plasma protein levels reveal TIMP2 role in cognitive performance. Research Square. PMID 39483923 DOI: 10.21203/rs.3.rs-5267673/v1  0.505
2024 Shen Y, Timsina J, Heo G, Beric A, Ali M, Wang C, Yang C, Wang Y, Western D, Liu M, Gorijala P, Budde J, Do A, Liu H, Gordon B, et al. CSF proteomics identifies early changes in autosomal dominant Alzheimer's disease. Cell. PMID 39332414 DOI: 10.1016/j.cell.2024.08.049  0.778
2024 Anastasi F, Genius P, Rodriguez-Fernandez B, Yang C, Gorijala P, Timsina J, Hernández-Villamizar F, Lorenzini L, Del Campo M, Sánchez-Benavides G, Minguillon C, Navarro A, Cruchaga C, Suárez-Calvet M, Vilor-Tejedor N. Polygenic proxies of age-related plasma protein levels reveal TIMP2 role in cognitive performance. Medrxiv : the Preprint Server For Health Sciences. PMID 39211866 DOI: 10.1101/2024.07.23.24310854  0.544
2024 Cruchaga C, Yang C, Gorijala P, Timsina J, Wang L, Liu M, Wang C, Brock W, Wang Y, Sung YJ. European and African-specific plasma protein-QTL and metabolite-QTL analyses identify ancestry-specific T2D effector proteins and metabolites. Research Square. PMID 39108494 DOI: 10.21203/rs.3.rs-3617016/v1  0.583
2024 Marsh TW, Western D, Timsina J, Gorijala P, Yang C, Pastor P, Liu M, Morris JC, Bateman RJ, Schindler SE, Sung YJ, Cruchaga C. A genetic and proteomic comparison of key AD biomarkers across tissues. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 39077866 DOI: 10.1002/alz.14139  0.676
2024 Debette S, Caro I, Western D, Namba S, Sun N, Kawaguchi S, He Y, Fujita M, Roshchupkin G, D'Aoust T, Duperron MG, Sargurupremraj M, Tsuchida A, Koido M, Ahmadi M, ... Yang C, et al. Proteogenomics in cerebrospinal fluid and plasma reveals new biological fingerprint of cerebral small vessel disease. Research Square. PMID 39011113 DOI: 10.21203/rs.3.rs-4535534/v1  0.724
2024 Yi H, Yang Q, Repaci C, Lee CM, Heo G, Timsina J, Gorijala P, Yang C, Budde J, Wang L, Cruchaga C, Sung YJ. TOPMed imputed genomics enhances genomic atlas of the human proteome in brain, cerebrospinal fluid, and plasma. Scientific Data. 11: 387. PMID 38627416 DOI: 10.1038/s41597-024-03140-3  0.625
2024 Wang L, Nykänen NP, Western D, Gorijala P, Timsina J, Li F, Wang Z, Ali M, Yang C, Liu M, Brock W, Marquié M, Boada M, Alvarez I, Aguilar M, et al. Proteo-genomics of soluble TREM2 in cerebrospinal fluid provides novel insights and identifies novel modulators for Alzheimer's disease. Molecular Neurodegeneration. 19: 1. PMID 38172904 DOI: 10.1186/s13024-023-00687-4  0.748
2023 Loomis SJ, Sadhu N, Fisher E, Gafson AR, Huang Y, Yang C, Hughes EE, Marshall E, Herman A, John S, Runz H, Jia X, Bhangale T, Bronson PG. Genome-wide study of longitudinal brain imaging measures of multiple sclerosis progression across six clinical trials. Scientific Reports. 13: 14313. PMID 37652990 DOI: 10.1038/s41598-023-41099-0  0.351
2023 Phillips B, Western D, Wang L, Timsina J, Sun Y, Gorijala P, Yang C, Do A, Nykänen NP, Alvarez I, Aguilar M, Pastor P, Morris JC, Schindler SE, Fagan AM, et al. Proteome wide association studies of LRRK2 variants identify novel causal and druggable proteins for Parkinson's disease. Npj Parkinson's Disease. 9: 107. PMID 37422510 DOI: 10.1038/s41531-023-00555-4  0.759
2023 Sung YJ, Yang C, Norton J, Johnson M, Fagan A, Bateman RJ, Perrin RJ, Morris JC, Farlow MR, Chhatwal JP, Schofield PR, Chui H, Wang F, Novotny B, Eteleeb A, et al. Proteomics of brain, CSF, and plasma identifies molecular signatures for distinguishing sporadic and genetic Alzheimer's disease. Science Translational Medicine. 15: eabq5923. PMID 37406134 DOI: 10.1126/scitranslmed.abq5923  0.753
2023 Cruchaga C, Western D, Timsina J, Wang L, Wang C, Yang C, Ali M, Beric A, Gorijala P, Kohlfeld P, Budde J, Levey A, Morris J, Perrin R, Ruiz A, et al. Proteogenomic analysis of human cerebrospinal fluid identifies neurologically relevant regulation and informs causal proteins for Alzheimer's disease. Research Square. PMID 37333337 DOI: 10.21203/rs.3.rs-2814616/v1  0.819
2023 Wang C, Western D, Yang C, Ali M, Wang L, Gorijala P, Timsina J, Ruiz A, Pastor P, Fernandez M, Panyard D, Engelman C, Deming Y, Boada M, Cano A, et al. Unique genetic architecture of CSF and brain metabolites pinpoints the novel targets for the traits of human wellness. Research Square. PMID 37333177 DOI: 10.21203/rs.3.rs-2923409/v1  0.8
2023 Panyard DJ, McKetney J, Deming YK, Morrow AR, Ennis GE, Jonaitis EM, Van Hulle CA, Yang C, Sung YJ, Ali M, Kollmorgen G, Suridjan I, Bayfield A, Bendlin BB, Zetterberg H, et al. Large-scale proteome and metabolome analysis of CSF implicates altered glucose and carbon metabolism and succinylcarnitine in Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 37218097 DOI: 10.1002/alz.13130  0.753
2022 Wisch JK, Butt OH, Gordon BA, Schindler SE, Fagan AM, Henson RL, Yang C, Boerwinkle AH, Benzinger TLS, Holtzman DM, Morris JC, Cruchaga C, Ances BM. Proteomic clusters underlie heterogeneity in preclinical Alzheimer's disease progression. Brain : a Journal of Neurology. PMID 36542469 DOI: 10.1093/brain/awac484  0.548
2022 Yang C, Fagan AM, Perrin RJ, Rhinn H, Harari O, Cruchaga C. Mendelian randomization and genetic colocalization infer the effects of the multi-tissue proteome on 211 complex disease-related phenotypes. Genome Medicine. 14: 140. PMID 36510323 DOI: 10.1186/s13073-022-01140-9  0.749
2021 Yang C, Farias FHG, Ibanez L, Suhy A, Sadler B, Fernandez MV, Wang F, Bradley JL, Eiffert B, Bahena JA, Budde JP, Li Z, Dube U, Sung YJ, Mihindukulasuriya KA, et al. Genomic atlas of the proteome from brain, CSF and plasma prioritizes proteins implicated in neurological disorders. Nature Neuroscience. PMID 34239129 DOI: 10.1038/s41593-021-00886-6  0.735
2020 Ibanez L, Bahena JA, Yang C, Dube U, Farias FHG, Budde JP, Bergmann K, Brenner-Webster C, Morris JC, Perrin RJ, Cairns NJ, O'Donnell J, Álvarez I, Diez-Fairen M, Aguilar M, et al. Functional genomic analyses uncover APOE-mediated regulation of brain and cerebrospinal fluid beta-amyloid levels in Parkinson disease. Acta Neuropathologica Communications. 8: 196. PMID 33213513 DOI: 10.1186/s40478-020-01072-8  0.756
2019 Li Z, Farias FHG, Dube U, Del-Aguila JL, Mihindukulasuriya KA, Fernandez MV, Ibanez L, Budde JP, Wang F, Lake AM, Deming Y, Perez J, Yang C, Bahena JA, Qin W, et al. The TMEM106B FTLD-protective variant, rs1990621, is also associated with increased neuronal proportion. Acta Neuropathologica. PMID 31456032 DOI: 10.1007/S00401-019-02066-0  0.705
2019 Sapkota D, Lake AM, Yang W, Yang C, Wesseling H, Guise A, Uncu C, Dalal JS, Kraft AW, Lee JM, Sands MS, Steen JA, Dougherty JD. Cell-Type-Specific Profiling of Alternative Translation Identifies Regulated Protein Isoform Variation in the Mouse Brain. Cell Reports. 26: 594-607.e7. PMID 30650354 DOI: 10.1016/J.Celrep.2018.12.077  0.402
2019 Li Z, Farias FH, Dube U, Del-Aguila JL, Fernandez V, Ibanez L, Budde JP, Wang F, Lake AM, Robles Y, Perez J, Yang C, Mihindukulasuriya KA, Bradley J, Davenport R, et al. P3-116: TMEM106B PROTECTIVE VARIANT ASSOCIATED WITH INCREASED NEURONAL PROPORTION Alzheimer's & Dementia. 15: P974-P975. DOI: 10.1016/J.Jalz.2019.06.3144  0.72
2017 Dougherty JD, Yang C, Lake AM. Systems biology in the central nervous system: a brief perspective on essential recent advancements. Current Opinion in Systems Biology. 3: 67-76. PMID 29057378 DOI: 10.1016/J.Coisb.2017.04.011  0.417
2017 Hoye ML, Koval ED, Wegener AJ, Hyman TS, Yang C, O'Brien DR, Miller RL, Cole T, Schoch KM, Shen T, Kunikata T, Richard JP, Gutmann DH, Maragakis NJ, Kordasiewicz HB, et al. microRNA profiling reveals marker of motor neuron disease in ALS models. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28416596 DOI: 10.1523/Jneurosci.3582-16.2017  0.341
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