Kuchuan Chen - Publications

Affiliations: 
Boston Children's Hospital/Harvard Medical School 
Area:
Neuroscience

20 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Petrova V, Snavely AR, Splaine J, Zhen S, Singh B, Pandey R, Chen K, Cheng A, Hermawan C, Barrett LB, Smith JA, Woolf CJ. Identification of novel neuroprotectants against vincristine-induced neurotoxicity in iPSC-derived neurons. Cellular and Molecular Life Sciences : Cmls. 81: 315. PMID 39066803 DOI: 10.1007/s00018-024-05340-x  0.41
2024 Petrova V, Snavely AR, Splaine J, Zhen S, Singh B, Pandey R, Chen K, Cheng A, Hermawan C, Barrett LB, Smith JA, Woolf C. Identification of novel neuroprotectants against vincristine-induced neurotoxicity in iPSC-derived neurons. Research Square. PMID 39011110 DOI: 10.21203/rs.3.rs-4545853/v1  0.41
2024 Huang X, Lee S, Chen K, Kawaguchi R, Wiskow O, Ghosh S, Frost D, Perrault L, Pandey R, Klim JR, Boivin B, Hermawan C, Livak KJ, Geschwind DH, Wainger BJ, et al. Downregulation of the silent potassium channel Kv8.1 increases motor neuron vulnerability in amyotrophic lateral sclerosis. Brain Communications. 6: fcae202. PMID 38911266 DOI: 10.1093/braincomms/fcae202  0.669
2021 Huang X, Roet KCD, Zhang L, Brault A, Berg AP, Jefferson AB, Klug-McLeod J, Leach KL, Vincent F, Yang H, Coyle AJ, Jones LH, Frost D, Wiskow O, Chen K, et al. Human amyotrophic lateral sclerosis excitability phenotype screen: Target discovery and validation. Cell Reports. 35: 109224. PMID 34107252 DOI: 10.1016/j.celrep.2021.109224  0.672
2019 Klim JR, Williams LA, Limone F, Guerra San Juan I, Davis-Dusenbery BN, Mordes DA, Burberry A, Steinbaugh MJ, Gamage KK, Kirchner R, Moccia R, Cassel SH, Chen K, Wainger BJ, Woolf CJ, et al. ALS-implicated protein TDP-43 sustains levels of STMN2, a mediator of motor neuron growth and repair. Nature Neuroscience. PMID 30643292 DOI: 10.1038/S41593-018-0300-4  0.446
2018 Lin G, Lee PT, Chen K, Mao D, Tan KL, Zuo Z, Lin WW, Wang L, Bellen HJ. Phospholipase PLA2G6, a Parkinsonism-Associated Gene, Affects Vps26 and Vps35, Retromer Function, and Ceramide Levels, Similar to α-Synuclein Gain. Cell Metabolism. PMID 29909971 DOI: 10.1016/J.Cmet.2018.05.019  0.778
2016 Chen K, Ho TS, Lin G, Tan KL, Rasband MN, Bellen HJ. Loss of Frataxin activates the iron/sphingolipid/PDK1/Mef2 pathway in mammals. Elife. 5. PMID 27901468 DOI: 10.7554/Elife.20732  0.721
2016 Chen K, Lin G, Haelterman NA, Ho TS, Li T, Li Z, Duraine L, Graham BH, Jaiswal M, Yamamoto S, Rasband MN, Bellen HJ. Loss of Frataxin induces iron toxicity, sphingolipid synthesis, and Pdk1/Mef2 activation, leading to neurodegeneration. Elife. 5. PMID 27343351 DOI: 10.7554/Elife.16043  0.741
2016 Li T, Fan J, Blanco-Sánchez B, Giagtzoglou N, Lin G, Yamamoto S, Jaiswal M, Chen K, Zhang J, Wei W, Lewis MT, Groves AK, Westerfield M, Jia J, Bellen HJ. Ubr3, a Novel Modulator of Hh Signaling Affects the Degradation of Costal-2 and Kif7 through Poly-ubiquitination. Plos Genetics. 12: e1006054. PMID 27195754 DOI: 10.1371/Journal.Pgen.1006054  0.747
2016 Ugur B, Chen K, Bellen HJ. Drosophila tools and assays for the study of human diseases. Disease Models & Mechanisms. 9: 235-44. PMID 26935102 DOI: 10.1242/Dmm.023762  0.746
2016 Chen K, Ho TS, Lin G, Tan KL, Rasband MN, Bellen HJ. Author response: Loss of Frataxin activates the iron/sphingolipid/PDK1/Mef2 pathway in mammals Elife. DOI: 10.7554/Elife.20732.015  0.529
2016 Chen K, Lin G, Haelterman NA, Ho TS, Li T, Li Z, Duraine L, Graham BH, Jaiswal M, Yamamoto S, Rasband MN, Bellen HJ. Author response: Loss of Frataxin induces iron toxicity, sphingolipid synthesis, and Pdk1/Mef2 activation, leading to neurodegeneration Elife. DOI: 10.7554/Elife.16043.018  0.759
2015 Nagarkar-Jaiswal S, Lee PT, Campbell ME, Chen K, Anguiano-Zarate S, Gutierrez MC, Busby T, Lin WW, He Y, Schulze KL, Booth BW, Evans-Holm M, Venken KJ, Levis RW, Spradling AC, et al. A library of MiMICs allows tagging of genes and reversible, spatial and temporal knockdown of proteins in Drosophila. Elife. 4. PMID 25824290 DOI: 10.7554/Elife.05338  0.734
2015 Nagarkar-Jaiswal S, Lee P, Campbell ME, Chen K, Anguiano-Zarate S, Gutierrez MC, Busby T, Lin W, He Y, Schulze KL, Booth BW, Evans-Holm M, Venken KJ, Levis RW, Spradling AC, et al. Author response: A library of MiMICs allows tagging of genes and reversible, spatial and temporal knockdown of proteins in Drosophila Elife. DOI: 10.7554/Elife.05338.023  0.512
2014 Wong CO, Chen K, Lin YQ, Chao Y, Duraine L, Lu Z, Yoon WH, Sullivan JM, Broadhead GT, Sumner CJ, Lloyd TE, Macleod GT, Bellen HJ, Venkatachalam K. A TRPV channel in Drosophila motor neurons regulates presynaptic resting Ca2+ levels, synapse growth, and synaptic transmission. Neuron. 84: 764-77. PMID 25451193 DOI: 10.1016/J.Neuron.2014.09.030  0.64
2014 Sandoval H, Yao CK, Chen K, Jaiswal M, Donti T, Lin YQ, Bayat V, Xiong B, Zhang K, David G, Charng WL, Yamamoto S, Duraine L, Graham BH, Bellen HJ. Mitochondrial fusion but not fission regulates larval growth and synaptic development through steroid hormone production. Elife. 3. PMID 25313867 DOI: 10.7554/Elife.03558  0.733
2014 Yamamoto S, Jaiswal M, Charng WL, Gambin T, Karaca E, Mirzaa G, Wiszniewski W, Sandoval H, Haelterman NA, Xiong B, Zhang K, Bayat V, David G, Li T, Chen K, et al. A drosophila genetic resource of mutants to study mechanisms underlying human genetic diseases. Cell. 159: 200-14. PMID 25259927 DOI: 10.1016/J.Cell.2014.09.002  0.647
2014 Charng WL, Yamamoto S, Jaiswal M, Bayat V, Xiong B, Zhang K, Sandoval H, David G, Gibbs S, Lu HC, Chen K, Giagtzoglou N, Bellen HJ. Drosophila Tempura, a novel protein prenyltransferase α subunit, regulates notch signaling via Rab1 and Rab11. Plos Biology. 12: e1001777. PMID 24492843 DOI: 10.1371/Journal.Pbio.1001777  0.721
2014 Sandoval H, Yao C, Chen K, Jaiswal M, Donti T, Lin YQ, Bayat V, Xiong B, Zhang K, David G, Charng W, Yamamoto S, Duraine L, Graham BH, Bellen HJ. Author response: Mitochondrial fusion but not fission regulates larval growth and synaptic development through steroid hormone production Elife. DOI: 10.7554/Elife.03558.023  0.72
2012 Chen YC, Lin YQ, Banerjee S, Venken K, Li J, Ismat A, Chen K, Duraine L, Bellen HJ, Bhat MA. Drosophila neuroligin 2 is required presynaptically and postsynaptically for proper synaptic differentiation and synaptic transmission. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 16018-30. PMID 23136438 DOI: 10.1523/Jneurosci.1685-12.2012  0.728
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